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Search Results for " db "

Targets Recommended: Apoptosis Others

269

抑制剂 & 化合物

7

天然产物

17

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10964	DB1976	Apoptosis; Others	Apoptosis; Others
	DB1976 是一种 DB270 的硒烯类似物，是一种高效且可渗透细胞的转录因子 PU.1 的抑制剂。在体外，DB1976 有效抑制 PU.1 结合 (IC50 为 10 nM)，可强烈抑制 PU.1/DNA 复合物 (具有高 DB1976-λB 亲和力，KD 为 12 nM)。DB1976 具有诱导细胞凋亡的作用。
T3200	DB07268	JNK	MAPK
	DB07268 是选择性JNK1抑制剂，IC50值为 9 nM。
T64372	DB722	Others	Others
	DB722是一种具有DNA 结合活性的呋喃脒类似物。DB722显示抗增殖活性。
T9707	DB2313 Carboximidamide	Apoptosis	Apoptosis
	DB2313 (Carboximidamide) 是一种有效的转录因子 PU.1 抑制剂，IC50 为 14 nM。DB2313 破坏了 PU.1 与靶基因启动子的相互作用。DB2313 可诱导急性髓细胞性白血病 (AML) 细胞凋亡 (apoptosis)，并具有抗癌作用。
T15055	DB04760 MMP-13 Inhibitor	MMP	Proteases/Proteasome
	DB04760 是一种高选择性和有效的 MMP-13 非锌螯合抑制剂（IC50：8 nM）。DB04760 能明显降低紫杉醇的神经毒性，并具有抗癌活性。
T24421	LY-2624803 DB-7,LY2624803,HY-10275,LY 2624803	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	LY-2624803 是一种 5-HT2A 受体拮抗剂和组胺受体反向激动剂，可用于改善慢波睡眠。
T27124	DB-959 (salt) T3D959,T-3D-959,T-3D959,DB-959Na,DB959Na
	DB-959, a PPAR agonist, is used potentially for the treatment of Alzheimer's disease.
Fr13634	4-Aminobenzamide 红色基DB-70
	Compound Fr13634 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 Fr13634，CAS号为 2835-68-9。
T31215	DB-766 DB766
	DB-766 is a potential chemotherapeutic candidate for Chagas' disease treatment. DB-766 exhibits strong trypanocidal activity and excellent selectivity for bloodstream trypomastigotes and intracellular amastigotes (Y strain), giving IC(50)s of 60 and 25 nM
T69674	DB-310
	DB-310 is a novel LMP2 inhibitor as a potential treatment for Alzheimer's disease.
T23967	DB-959 (free base)
	DB-959 is a potential agonist of PPAR.
T31425	Dibenz[a,h]anthracene CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A	DNA	DNA Damage/DNA Repair
	Dibenz[a,h]anthracene (CCRIS 208) 诱导细菌DNA 损伤和基因突变，并在几种哺乳动物细胞培养物中诱导基因突变和转化。
T23966	DB772 DB 772,DB-772
	DB772 is a scrapie prion accumulation inhibitor.
T24587	Pafuramidine maleate DB-289,DB289,DB 289
	Pafuramidine is an orally bioavailable prodrug of formamidine which was developed for the treatment of human African trypanosomiasis.
T77925	DB-0646	PROTACs	PROTAC
	DB-0646是一种靶向蛋白降解剂（PROTAC），具有多激酶抑制特性。
T26003	Pyrazinobutazone DB139,Carudol,DB-139,Ranoroc,DB 139
	Pyrazinobutazone is an antipyrene derivative which possesses anti-inflammatory properties.
T68487	DB1055
	DB1055 is a novel HOXA9 Transcription Factor Inhibitor, dedemonstrating for the first time the propensity of sequence-selective DNA ligands to inhibit HOXA9/DNA binding.
T74101	DB-3-291
	DB-3-291 是一种有效和选择性的CSK 降解剂，Kd 值为 1 nM。
T68359	DB1255
	DB1255 is a ERG/DNA binding inhibitor which targets the DNA-binding activity of the human ERG transcription factor.
T9958	DB818	Others	Others
	DB818 是一种合成的 Homeobox A9 (HOXA9) 抑制剂，可用于治疗与 HOXA9 过表达相关的急性髓细胞白血病。
T31891	Furidarone DB 136,Furidarona,Furidaronum
	Furidarone is a biochemical.
T23898	Clocoumarol Clocoumarolum,BRN 1264788,DB 112
	Clocoumarol is an anticoagulant that prevents blood clotting. It also can inhibit the dilatation of the spleen and the congestion of lymph nodes.
T10964L	DB1976 dihydrochloride DB1976 hydrochloride,DB1976 2HCl	Apoptosis; NF-κB	Apoptosis; NF-κB
	DB1976 dihydrochloride (DB1976 2HCl) ，一种转录因子 PU.1 抑制剂，具有潜在抗炎活性，可在体内实验中减缓小鼠的炎症和纤维化，改善了葡萄糖稳态和血脂异常。DB1976 dihydrochloride 促进细胞凋亡，可用于研究代谢功能障碍和非酒精性脂肪性肝炎。
T38778	DB2115 tertahydrochloride DB2115 tertahydrochloride
	DB2115 (tertahydrochloride) is a powerful inhibitor of the myeloid master regulator PU.1. With significant potential in cancer research, particularly hematologic cancers like leukemia, as well as other conditions linked to PU.1 dysfunction, DB2115 (tertahydrochloride) offers promising avenues of study.
T71585	DB03417
	DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.
T69857	DB293
	DB293 is an inhibitor of PIT-1 and BRN-3 transcription factors. DB293 binds as head-to-tail stacked dimers in the minor groove of 5'-ATGA sequence, thereby leading to an increase in the size of minor groove.
T24414	Lofepramine hydrochloride WHR-2908A,DB-2182,WHR 2908A
	Lofepramine is a serotonin and norepinephrine reuptake inhibitor. Lofepramine is also a psychotropic IMIPRAMINE derivative.
T23994	Dibenzo(a,i)pyrene DB(a,i)p,Benzo(rst)pentaphene
	Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.
T27395	Furamidine dihydrochloride DB 75, DB75, NSC 305831, WR199385,Furamidine HCl
	Furamidine is a cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine binds to strings of AT base pair sequences in DNA′s minor groove. Furamidine targets the enzyme active site and is primarily competitive with t
T2330	Rilpivirine TMC278,R278474,利匹韦林,DB08864	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Rilpivirine (R278474) 是一种二芳基嘧啶衍生物和非核苷逆转录酶抑制剂，具有抗 HIV-1 的抗病毒活性，用于治疗 HIV 感染。
T32737	Liafensine BMS820836,BMS 820836,DB104,BMS-820836	Dopamine Receptor; 5-HT Receptor; Norepinephrine	GPCR/G Protein; Neuroscience
	Liafensine(BMS-820836) 是一种新型且具有选择性的三重单胺再摄取抑制剂，对血清素、去甲肾上腺素和多巴胺的再摄取具有抑制作用，可用于研究重度抑郁症和中枢神经系统疾病。
T15056	DB07107	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
T16428	Pafuramidine DB289	Others	Others
	Pafuramidine is an orally bioavailable prodrug of furamidine. It has activity against Pneumocystis pneumonia (IC50 value: 4.5 nM)
T71583	Amlodipine hydrochloride, (R)-
	Amlodipine hydrochloride, (R)-, is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers blood pressure. In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina.
T69841	GC813 sodium
	GC813 is a potent and permeable inhibitor of MERS coronavirus 3CL protease. GC813 is analogue of GC376.
T69856	Pralurbactam
	Pralurbactam 是 β -内酰胺酶抑制剂。Pralurbactam 可用于细菌感染的研究。
T69673	Deucrictibant
	Deucrictibant is a bradykinin receptor antagonist.
T11338	Furamidine DB75,NSC 305831	Others	Others
	Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine (DB75) is abisbenzamidine derivative and an antiparasite agent. Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and ...
T19272	DB04760 analog 1	Others	Others
	DB04760 analog 1 is an analogue of DB04760.
T74642	DB1113
	DB1113 (Example 24) 是一种靶向蛋白激酶降解的双功能化合物。DB1113 可降解 ABL1，ABL2，BLK，CDK11B，CDK4，CSK，EPHA3，FER，GAK，LIMK1，MAP3K20，MAP4K1，MAP4K2，MAP4K3，MAP4K5，MAPK14，MAPK7，MAPK8，MAPK9，MAPKAPK2，MAPKAPK3，NLK，PDIK1L，PTK2B，RIPK1，RPS6KA1，RPS6KA3，SIK2，SIK3，STK35，TNK2 和 ULK1。DB1113 可用于研究异常激酶活性介导的疾病或紊乱。
T73542	DB008
	DB008 是一种有效的选择性PARP16抑制剂，IC50值为 0.27 μM，含有丙烯酰胺亲电试剂。DB008 具有膜渗透性，可选择性标记PARP16。
T74644	DB0614
	DB1113 (Example 24) 是一种靶向蛋白激酶降解的双功能化合物。DB1113 可降解ABL1，ABL2，BLK，CDK11B，CDK4，CSK，EPHA3，FER，GAK，LIMK1，MAP3K20，MAP4K1，MAP4K2，MAP4K3，MAP4K5，MAPK14，MAPK7，MAPK8，MAPK9，MAPKAPK2，MAPKAPK3，NLK，PDIK1L，PTK2B，RIPK1，RPS6KA1，RPS6KA3，SIK2，SIK3，STK35，TNK2 和ULK1。DB1113 可用于研究异常激酶活性介导的疾病或紊乱。
T69842	DB2313 HCl
	DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.
T63412	DB772 hydrate
	DB772 hydrate 是一种牛病毒性腹泻病毒 (BVDV) 抑制剂，同时表现出抗朊病毒作用。
T69354	Enzastaurin 2HCl
	Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
T71853	Enzastaurin HCl
	Enzastaurin HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
T82605	DB21, Galectin-1 Antagonist	Galectin	Immunology/Inflammation
	DB21, Galectin-1 Antagonist 是一种用于抑制galectin-1 (GAL1)与细胞表面聚糖结合的二苯并呋喃缀合肽模拟物。在黑色素瘤、肺腺癌和卵巢癌模型中，该化合物能增强血管生成和肿瘤生长的抑制效果。
T27933	LY243246 LY249543 disodium,LY249543 sodium,LY 249543,LY-249543,S-isomer of lometrexol,DB04322,LY249543
	LY249543, the S-isomer of lometrexol, is an inhibitor of Methylenetetrahydrofolate Dehydrogenase/Cycl.
T15073	DBCO-PEG4-NHS ester	PROTAC Linker	PROTAC
	DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T15067	DBCO-NHS ester	Others	Others
	DBCO-NHS ester 是一种 ADC 连接剂，可裂解的 3 单元 PEG，还可以用于合成抗体药物共轭物 (ADC)。

化合物

Cat.No: T10964

Target: Apoptosis, Others

Cat.No: T3200

Target: JNK

Cat.No: T64372

Target: Others

Cat.No: T9707

Synonym: Carboximidamide

Target: Apoptosis

Cat.No: T15055

Synonym: MMP-13 Inhibitor

Target: MMP

Cat.No: T24421

Synonym: DB-7,LY2624803,HY-10275,LY 2624803

Target: 5-HT Receptor, Histamine Receptor

Cat.No: T27124

Synonym: T3D959,T-3D-959,T-3D959,DB-959Na,DB959Na

4-Aminobenzamide

Cat.No: Fr13634

Synonym: 红色基DB-70

Cat.No: T31215

Synonym: DB766

Cat.No: T69674

DB-959 (free base)

Cat.No: T23967

Dibenz[a,h]anthracene

Cat.No: T31425

Synonym: CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A

Target: DNA

Cat.No: T23966

Synonym: DB 772,DB-772

Pafuramidine maleate

Cat.No: T24587

Synonym: DB-289,DB289,DB 289

Cat.No: T77925

Target: PROTACs

Pyrazinobutazone

Cat.No: T26003

Synonym: DB139,Carudol,DB-139,Ranoroc,DB 139

Cat.No: T68487

Cat.No: T74101

Cat.No: T68359

Cat.No: T9958

Target: Others

Cat.No: T31891

Synonym: DB 136,Furidarona,Furidaronum

Cat.No: T23898

Synonym: Clocoumarolum,BRN 1264788,DB 112

DB1976 dihydrochloride

Cat.No: T10964L

Synonym: DB1976 hydrochloride,DB1976 2HCl

Target: Apoptosis, NF-κB

DB2115 tertahydrochloride

Cat.No: T38778

Synonym: DB2115 tertahydrochloride

Cat.No: T71585

Cat.No: T69857

Lofepramine hydrochloride

Cat.No: T24414

Synonym: WHR-2908A,DB-2182,WHR 2908A

Dibenzo(a,i)pyrene

Cat.No: T23994

Synonym: DB(a,i)p,Benzo(rst)pentaphene

Furamidine dihydrochloride

Cat.No: T27395

Synonym: DB 75, DB75, NSC 305831, WR199385,Furamidine HCl

Cat.No: T2330

Synonym: TMC278,R278474,利匹韦林,DB08864

Target: HIV Protease, Reverse Transcriptase

Cat.No: T32737

Synonym: BMS820836,BMS 820836,DB104,BMS-820836

Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine

Cat.No: T15056

Target: Akt

Cat.No: T16428

Synonym: DB289

Target: Others

Amlodipine hydrochloride, (R)-

Cat.No: T71583

Cat.No: T69841

Cat.No: T69856

Cat.No: T69673

Cat.No: T11338

Synonym: DB75,NSC 305831

Target: Others

DB04760 analog 1

Cat.No: T19272

Target: Others

Cat.No: T74642

Cat.No: T73542

Cat.No: T74644

Cat.No: T69842

Cat.No: T63412

Enzastaurin 2HCl

Cat.No: T69354

Enzastaurin HCl

Cat.No: T71853

DB21, Galectin-1 Antagonist

Cat.No: T82605

Target: Galectin

Cat.No: T27933

Synonym: LY249543 disodium,LY249543 sodium,LY 249543,LY-249543,S-isomer of lometrexol,DB04322,LY249543

DBCO-PEG4-NHS ester

Cat.No: T15073

Target: PROTAC Linker

Cat.No: T15067

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN3484	Bakkenolide Db	Others	Others
	Bakkenolide Db may have cytotoxicity.
T80779	WDB002
	WDB002，一种FK506/雷帕霉素家族的天然产物，靶向CEP250，可应用于COVID-19研究。
T3414	Morroniside 莫诺苷,奎宁树	Apoptosis; MMP; Pyroptosis	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
TN3532	Borapetoside E	Others	Others
	Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice.
T5706	8-epidiosbulbin E acetate	Others	Others
	8-epidiosbulbin E acetate 是亚洲国家广泛使用的传统草药 Dioscorea bulbifera L. (DB) 中含量丰富的二萜内酯。
T38250	L-Sepiapterin
	L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-de...
TN3779	De-O-methyllasiodiplodin	IL Receptor; TNF; ROS; Antifection	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects on induced NO production. De-O-methyllasiodiplodin effectively lowers the blood glucose level in d

天然产物

Cat.No: TN3484

Target: Others

Cat.No: T80779

Cat.No: T3414

Synonym: 莫诺苷,奎宁树

Target: Apoptosis, MMP, Pyroptosis

Cat.No: TN3532

Target: Others

8-epidiosbulbin E acetate

Cat.No: T5706

Target: Others

Cat.No: T38250

De-O-methyllasiodiplodin

Cat.No: TN3779

Target: IL Receptor, TNF, ROS, Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00411	LEPR Protein, Human, Recombinant (hFc) LEPR,Leptin receptor,OB-R,OB receptor,OBR,CD295,DB,...	Human	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS...
TMPJ-00976	LEPR Protein, Mouse, Recombinant (His) OBR,DB,Leptin receptor,OB receptor,CD295,OB-R,LEPR,...	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS...
TMPJ-00977	LEPR Protein, Mouse, Recombinant (mFc) LEPR,CD295,OB-R,LEP-R,HuB219,Leptin receptor,OBR,DB...	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS...
TMPJ-00975	LEPR Protein, Mouse, Recombinant (hFc) CD295,DB,HuB219,OB receptor,LEP-R,Leptin receptor,O...	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS...
TMPH-02492	DBI Protein, Mouse, Recombinant (His & Myc) Endozepine (EP),Diazepam-binding inhibitor,DBI,Acyl...	Mouse	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
TMPH-02972	VDB Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
TMPH-03561	lsdB Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization. Promotes also resistance to hydrogen peroxide and killing by neutrophils.
TMPY-05552	DBT Protein, Human, Recombinant (His) E2,BCKAD-E2,BCKADE2,DBT,BCATE2,RP11-35E17.3,E2B	Human	Baculovirus-Insect Cells
	DBT Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 48.8 kDa. Accession number: P11182
TMPY-03991	DBI Protein, Human, Recombinant (His) diazepam binding inhibitor (GABA receptor modulator, acyl-Co...	Human	E. coli
	The diazepam binding inhibitor (DBI), alternatively known as the acyl-CoA binding protein (ACBP), is involved in multiple biological actions. The polypeptide binds to the peripheral, or mitochondrial, benzodiazepine receptor and facilitates transport of cholesterol to the inner membrane to stimulate steroid synthesis. Through this action, DBI indirectly modulates gamma-aminobutyric acid (GABA)-mediated inhibitory neurotransmission. DBI can be postulated as a candidate gene for psychiatric phenot...
TMPH-02973	VDB Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
TMPH-00890	DBI Protein, Human, Recombinant (aa 2-104, His) Acyl-CoA-binding protein,Diazepam-binding inhibitor,DB	Human	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
TMPH-02178	TARDBP Protein, Human, Recombinant	Human	E. coli
	RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs. In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases. Plays a role in maintaining mitoch...
TMPJ-00759	VDB Protein, Human, Recombinant (His) Group-Specific Component,DBP,VDB,GC,Gc-Glo...	Human	Human Cells
	Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on...
TMPH-02179	TARDBP Protein, Human, Recombinant (His)	Human	Yeast
	RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs. In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases. Plays a role in maintaining mitoch...
TMPH-03235	DBI Protein, Rat, Recombinant (His & Myc) Endozepine (EP),ACBP,DBI,Acyl-CoA-binding protein,D...	Rat	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
TMPK-00839	ITGB6 Protein, Human, Recombinant (His) β6,Integrin β-6,β 6,beta 6,Integrin β 6,Integrin beta-6,Inte...	Human	HEK293
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene.
TMPK-01247	ITGB6 Protein, Mouse, Recombinant (His) ITGB6,Integrin β-6,Integrin beta-6	Mouse	HEK293
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene.

重组蛋白

LEPR Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00411

Species: Human

Expression System: Human Cells

LEPR Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00976

Species: Mouse

Expression System: Human Cells

LEPR Protein, Mouse, Recombinant (mFc)

Cat.No: TMPJ-00977

Species: Mouse

Expression System: Human Cells

LEPR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00975

Species: Mouse

Expression System: Human Cells

DBI Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02492

Species: Mouse

Expression System: E. coli

VDB Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02972

Species: Mouse

Expression System: E. coli

lsdB Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03561

Species: Staphylococcus aureus

Expression System: E. coli

DBT Protein, Human, Recombinant (His)

Cat.No: TMPY-05552

Species: Human

Expression System: Baculovirus-Insect Cells

DBI Protein, Human, Recombinant (His)

Cat.No: TMPY-03991

Species: Human

Expression System: E. coli

VDB Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02973

Species: Mouse

Expression System: Yeast

DBI Protein, Human, Recombinant (aa 2-104, His)

Cat.No: TMPH-00890

Species: Human

Expression System: E. coli

TARDBP Protein, Human, Recombinant

Cat.No: TMPH-02178

Species: Human

Expression System: E. coli

VDB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00759

Species: Human

Expression System: Human Cells

TARDBP Protein, Human, Recombinant (His)

Cat.No: TMPH-02179

Species: Human

Expression System: Yeast

DBI Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03235

Species: Rat

Expression System: E. coli

ITGB6 Protein, Human, Recombinant (His)

Cat.No: TMPK-00839

Species: Human

Expression System: HEK293

ITGB6 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01247

Species: Mouse

Expression System: HEK293

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