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57

抑制剂 & 化合物

21

天然产物

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Cat. No. Product Name Target Signaling Pathways
T39703 ATRA-biotin

ATRA-biotin,Biotin-ATRA-conjugate

ATRA-biotin is a biotin-conjugated form of all-trans retinoic acid (ATRA). It is utilized for the purpose of tracking ATRA within cells or specific tissues.
T35629 ATRA-BA Hybrid

ATRA-BA hybrid is a mutual prodrug form of all-transretinoic acid and butyric acid .1ATRA-BA hybrid is cleaved to release ATRA and BA in isolated mouse plasma. It inhibits the growth of MDA-MB-231 breast and PC3 prostate cancer cells with GI50values of 0.01 and 1.02 μM, respectively. ATRA-BA (20 μM) has 15-fold greater antiproliferative activity in PC3 cells compared to an equimolar concentration of ATRA and BA. 1.Gediya, L.K., Khandelwal, A., Patel, J., et al.Design, synthesis, and evaluation o...
T17733 ATRA-hydroxyimino

CRABP-II ligand 1

Others Others
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].
T67921 Retinoic acid-d5

all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5

Retinoid Receptor Metabolism
Retinoic acid-d5 (Vitamin A acid-d5)是视黄酸的氘标记形式。视黄酸是一种天然的RAR 核受体激动剂, 对 RARα/β/γ 的 IC50 为 14 nM,与 PPARβ/δ 结合的Kd 为 17 nM。视黄酸是维生素a 的代谢物,在细胞生长、分化和器官发育中起着重要作用。视黄酸通过激活视黄酸受体α作为转录因子Nrf2的抑制剂来发挥作用。
T23154 Piclamilast

RPR 73401,RP 73401,吡拉米司特

PDE Metabolism
Piclamilast (RP 73401) 是一种有效的磷酸二酯酶 4(PDE4)的抑制剂,对猪主动脉和可溶性嗜酸性粒细胞中的 IC50值分别为 16 nM 和 2 nM。
T5626 Atrazine

Aktikon,Chromozin,Gesaprim,莠去津,Oleogesaprim,阿特拉津

Others Others
Atrazine (Oleogesaprim) 能够抑制光磷酸化,但通不会在短期内导致致命性或永久性细胞损伤,常用于控制一年生阔叶杂草。
T17265 Ximelagatran

EXANTA,H 376-95,H37695,希美加群,H 376/95,H-37695,H 37695

Thrombin Proteases/Proteasome
Ximelagatran (H 376-95) 是一种口服活性凝血酶抑制剂,可选择性的、竞争性的抑制游离和凝块结合的凝血酶。它是一种抗凝药物,具有快速起效的抗凝作用,可预测的,剂量依赖性的药代动力学和药效学。
T7221 Satraplatin

BMS182751,JM216,顺式-二氯-反式-二乙酸-氨-环己胺合铂,BMY45594

DNA Alkylator/Crosslinker; DNA Alkylation DNA Damage/DNA Repair
Satraplatin (BMS182751) 是一种烷化剂 ,是一种口服的抗肿瘤铂 (IV) 复合物,具有广泛的抗肿瘤效果。
T10951 Dabigatran ethyl ester hydrochloride

N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐

Others; Thrombin Others; Proteases/Proteasome
Dabigatran ethyl ester hydrochloride 是一种核糖基二氢烟酰胺脱氢酶抑制剂,IC50=0.8 μM,也是一种凝血酶的抑制剂。
T1459 Cisatracurium besylate

顺苯磺酸阿曲库铵,顺苯磺阿曲库铵,51W89

Adrenergic Receptor; AChR; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Cisatracurium besylate (51W89) 是一种用于静脉内给药的非去极化骨骼肌松弛剂。
T5133 Dabigatran Etexilate Mesylate

甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate

Thrombin Proteases/Proteasome
Dabigatran Etexilate Mesylate (BIBR 1048MS) 是一种口服具有活性的 Dabigatran 前药,具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。
T6397 Atracurium besylate

Tracrium,51W89,BW-33A,苯磺酸阿曲库铵

AChR Neuroscience
Atracurium besylate (51W89) 是一种神经肌肉阻断剂,ED95为0.2 mg/kg。
T31806 Flovagatran

TGN 255

Thrombin Proteases/Proteasome
Flovagatran (TGN 255) 是一种具有口服活性和有效性的凝血酶和肠外直接因子 II 抑制剂。Flovagatran 可用于研究静脉血栓栓塞。
T6295 Dabigatran

BIBR 953,BIBR 953ZW,达比加群

Thrombin Proteases/Proteasome
Dabigatran (BIBR 953ZW) 是一种口服抗凝剂,是一种可逆的,竞争性的直接凝血酶 (thrombin) 抑制剂,Ki=4.5 nM。它也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。
T30191L Atecegatran TFA

Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA

Others Others
Atecegatran TFA 常被当作一种抗凝血剂,可用来治疗心血管疾病。
T5642 Tegatrabetan

BC2059

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Tegatrabetan (BC2059) 是β-Catenin 拮抗剂,能够破坏 β-catenin 与转导素 β 样蛋白 1 (TBL1) 结合。
T16098 Islatravir

MK-8591

HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Islatravir (MK-8591) 是一种核苷逆转录酶抑制剂,是抗HIV-1药物,对 HIV-1 (WT),HIV-1 (M184V),HIV-1 (MDR) 的EC50值分别为 0.068 nM,3.1 nM 和 0.15 nM。
T25364L Efegatran sulfate

LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate

Thrombin Proteases/Proteasome
Efegatran sulfate (LY294468 sulfate) 是一种有效的凝血酶抑制剂,可用于治疗血栓类疾病。
T0389 Dabigatran etexilate

达比加群酯,BIBR 1048

Thrombin Proteases/Proteasome
Dabigatran etexilate (BIBR 1048) 是一种 Dabigatran 前药,具有口服活性。它具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。
TQ0259 Atrasentan

A-147627,(+)-A 127722,阿曲生坦,ABT-627

Endothelin Receptor GPCR/G Protein
Atrasentan (ABT-627) 是内皮素受体 (endothelin receptor) 拮抗剂,能够抑制 ETA 的活性(IC50:0.0551 nM)。
TQ0270 Atrasentan hydrochloride

(+)-A 127722 hydrochloride,ABT-627 hydrochloride,盐酸阿曲生坦,A-147627 hydrochloride

Endothelin Receptor GPCR/G Protein
Atrasentan hydrochloride (ABT-627 hydrochloride) 是内皮素 A 受体选择性拮抗剂,抑制内皮素 A 受体活性的IC50为 0.0551 nM。
T11994 Melagatran

Thrombin Proteases/Proteasome
Melagatran 是一种直接作用且可口服的凝血酶抑制剂。Melagatran 专一性抑制凝血酶,但不影响凝血级联中的其他酶或纤溶酶。Melagatran不依赖内源性辅因子发挥其抗凝血酶效果,可缓解内毒素血症的有害影响。因此,Melagatran作为预防动脉闭塞的策略显示出前景。
T12015 Methyl homoveratrate

Others Others
Methyl homoveratrate 是血浆、尿液和粪便提取物中 McN5691 的代谢物,是电压依赖性钙通道阻滞剂。
T70198 Atrasentan sodium

Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
T10950 Dabigatran D4 hydrochloride

BIBR-953 D4 hydrochloride

Others Others
Dabigatran D4 hydrochloride is deuterium-labeled dabigatran, which is a reversible and selective direct thrombin inhibitor (DTI) with a Ki value of 4.5 nM.
T76712 Satralizumab

Satralizumab为一种人源化单克隆抗体,有效抑制白细胞介素-6(IL-6)。此抗体能防止dTAA在褐家鼠中的形成与发展,并可应用于视神经脊髓炎(NMOSD)及降胸主动脉动脉瘤(dTAA)的研究。
T78319 Gatralimab

GZ-402668

Gatralimab(GZ-402668)为IgG1类抗CD52单克隆抗体。
T36469 Atrazine Mercapturate

Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine , an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animals, have diverse effects on the reproductive system in animals and humans, and disrupt the normal function of the endocrine system. Atrazine mercapturate is readily measured in urine samples.
T69507 Silatrane

Silatrane is a reversible cholinesterase inhibitor and anti-tumor agent.
T39310 Sofigatran

索非加群,MCC-977

Sofigatran (MCC-977) is an orally active inhibitor of factor IIa, also known as thrombin, and functions as an anticoagulant. It is primarily utilized in cardiovascular disease research.
T25364 Efegatran

LY 294468,LY294468,LY-294468

Efegatran is a hematologic agent and platelet aggregation inhibitor.
T24761 Satranidazole

GO 10213,C 10213 Go

Satranidazole is an anti-bacterial. It is used to treat periodontitis.
T16273 Napsagatran hydrate

Ro 46-6240/010 hydrate,Ro 46-6240 hydrate

Others Others
Napsagatran hydrate is a novel and specific inhibitor of thrombin.
T82717 cis-Indatraline hydrochloride

cis-Lu 19-005

cis-Indatraline (cis-Lu 19-005) hydrochloride 是一款用于神经退行性疾病研究的活性化合物。
T123832 Cynatratoside B

Cynatratoside B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T123832,CAS号为 97399-97-8。
T68488 Indatraline

Indatraline is a nonselective monoamine transporter inhibitor.
T27336 Flovagatran sodium

TGN255,TGN-255,TGN 255

Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.
T69456 Melagatran monohydrate

Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice.
T70233 Efegatran HCl

Efegatran, also known as GYKI-14166, RGH-2958 and LY294468, a thrombin inhibitor which is being developed by IVAX for the potential treatment of thromboembolic disorders.
T31915 Gatratet

Carbobenzoxy-trp-met-asp-phe-amide

Gatratet is a tetrapeptide.
T30191 Atecegatran

metabolite of AZD0837,atecegatran metoxil

Atecegatran 常被当作一种抗凝血剂属于,可用来治疗心血管疾病。
T11659 Inogatran

伊诺加群,H-314-27

Others Others
Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.
T75283 Atracurium

Atracurium (BW-33A free acid)为高效的竞争性非去极化神经肌肉阻滞剂,兼具AChR受体拮抗作用。该化合物能够诱导支气管收缩及实现神经肌肉阻滞,并促进星形胶质细胞分化[5]。
T34535 Satratoxin G

Satratoxin-G

Satratoxin G is a trichothecene mycotoxin of Stachybotrys chartarum and has been shown to selectively induces apoptosis in olfactory sensory neurons (OSNs) of the nose and brain.
T22867 Indatraline hydrochloride

Others Others
Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET)
T20888 Atraton

Atraton is an Agricultural Chemical.
T83873 Dabigatran Acyl-β-D-Glucuronide TFA

Dabigatran β-1-O-Acyl Glucuronide

Dabigatran acyl-β-D-glucuronide是凝血酶抑制剂dabigatran的一种活性代谢产物,主要通过UDP-葡萄糖醛酸转移酶(UGT)的UGT2B15亚型形成。在人体去除血小板的贫血浆中,Dabigatran acyl-β-D-glucuronide (0.46 µM) 能增加活化部分凝血活酶时间(aPTT)。
T30192 Atecegatran metoxil

Atecegatran fexenetil,AZD-0837,AZD 0837,AZD0837

Atecegatran Metoxil (Atecegatran Fexenetil ,AZD0837) is an oral direct thrombin inhibitor,which currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. AZD0837 is a selective and re
T126467 Atractysucrose IIIa

Atractysucrose IIIa 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126467,CAS号为 1053636-75-1。
T35939 Dabigatran Acyl-β-D-Glucuronide

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.

化合物

ATRA-biotin
Cat.No: T39703
Synonym: ATRA-biotin,Biotin-ATRA-conjugate
Target:
ATRA-BA Hybrid
Cat.No: T35629
Synonym:
Target:
ATRA-hydroxyimino
Cat.No: T17733
Synonym: CRABP-II ligand 1
Target: Others
Retinoic acid-d5
Cat.No: T67921
Synonym: all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5
Target: Retinoid Receptor
Piclamilast
Cat.No: T23154
Synonym: RPR 73401,RP 73401,吡拉米司特
Target: PDE
Atrazine
Cat.No: T5626
Synonym: Aktikon,Chromozin,Gesaprim,莠去津,Oleogesaprim,阿特拉津
Target: Others
Ximelagatran
Cat.No: T17265
Synonym: EXANTA,H 376-95,H37695,希美加群,H 376/95,H-37695,H 37695
Target: Thrombin
Satraplatin
Cat.No: T7221
Synonym: BMS182751,JM216,顺式-二氯-反式-二乙酸-氨-环己胺合铂,BMY45594
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Dabigatran ethyl ester hydrochloride
Cat.No: T10951
Synonym: N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐
Target: Others, Thrombin
Cisatracurium besylate
Cat.No: T1459
Synonym: 顺苯磺酸阿曲库铵,顺苯磺阿曲库铵,51W89
Target: Adrenergic Receptor, AChR, Autophagy
Dabigatran Etexilate Mesylate
Cat.No: T5133
Synonym: 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate
Target: Thrombin
Atracurium besylate
Cat.No: T6397
Synonym: Tracrium,51W89,BW-33A,苯磺酸阿曲库铵
Target: AChR
Flovagatran
Cat.No: T31806
Synonym: TGN 255
Target: Thrombin
Dabigatran
Cat.No: T6295
Synonym: BIBR 953,BIBR 953ZW,达比加群
Target: Thrombin
Atecegatran TFA
Cat.No: T30191L
Synonym: Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA
Target: Others
Tegatrabetan
Cat.No: T5642
Synonym: BC2059
Target: Wnt/beta-catenin
Islatravir
Cat.No: T16098
Synonym: MK-8591
Target: HIV Protease, Reverse Transcriptase
Efegatran sulfate
Cat.No: T25364L
Synonym: LY294468 sulfate,GYKI-14766 sulfate,LY 294468 sulfate,LY-294468 sulfate
Target: Thrombin
Dabigatran etexilate
Cat.No: T0389
Synonym: 达比加群酯,BIBR 1048
Target: Thrombin
Atrasentan
Cat.No: TQ0259
Synonym: A-147627,(+)-A 127722,阿曲生坦,ABT-627
Target: Endothelin Receptor
Atrasentan hydrochloride
Cat.No: TQ0270
Synonym: (+)-A 127722 hydrochloride,ABT-627 hydrochloride,盐酸阿曲生坦,A-147627 hydrochloride
Target: Endothelin Receptor
Melagatran
Cat.No: T11994
Synonym:
Target: Thrombin
Methyl homoveratrate
Cat.No: T12015
Synonym:
Target: Others
Atrasentan sodium
Cat.No: T70198
Synonym:
Target:
Dabigatran D4 hydrochloride
Cat.No: T10950
Synonym: BIBR-953 D4 hydrochloride
Target: Others
Satralizumab
Cat.No: T76712
Synonym:
Target:
Gatralimab
Cat.No: T78319
Synonym: GZ-402668
Target:
Atrazine Mercapturate
Cat.No: T36469
Synonym:
Target:
Silatrane
Cat.No: T69507
Synonym:
Target:
Sofigatran
Cat.No: T39310
Synonym: 索非加群,MCC-977
Target:
Efegatran
Cat.No: T25364
Synonym: LY 294468,LY294468,LY-294468
Target:
Satranidazole
Cat.No: T24761
Synonym: GO 10213,C 10213 Go
Target:
Napsagatran hydrate
Cat.No: T16273
Synonym: Ro 46-6240/010 hydrate,Ro 46-6240 hydrate
Target: Others
cis-Indatraline hydrochloride
Cat.No: T82717
Synonym: cis-Lu 19-005
Target:
Cynatratoside B
Cat.No: T123832
Synonym:
Target:
Indatraline
Cat.No: T68488
Synonym:
Target:
Flovagatran sodium
Cat.No: T27336
Synonym: TGN255,TGN-255,TGN 255
Target:
Melagatran monohydrate
Cat.No: T69456
Synonym:
Target:
Efegatran HCl
Cat.No: T70233
Synonym:
Target:
Gatratet
Cat.No: T31915
Synonym: Carbobenzoxy-trp-met-asp-phe-amide
Target:
Atecegatran
Cat.No: T30191
Synonym: metabolite of AZD0837,atecegatran metoxil
Target:
Inogatran
Cat.No: T11659
Synonym: 伊诺加群,H-314-27
Target: Others
Atracurium
Cat.No: T75283
Synonym:
Target:
Satratoxin G
Cat.No: T34535
Synonym: Satratoxin-G
Target:
Indatraline hydrochloride
Cat.No: T22867
Synonym:
Target: Others
Atraton
Cat.No: T20888
Synonym:
Target:
Dabigatran Acyl-β-D-Glucuronide TFA
Cat.No: T83873
Synonym: Dabigatran β-1-O-Acyl Glucuronide
Target:
Atecegatran metoxil
Cat.No: T30192
Synonym: Atecegatran fexenetil,AZD-0837,AZD 0837,AZD0837
Target:
Atractysucrose IIIa
Cat.No: T126467
Synonym:
Target:
Dabigatran Acyl-β-D-Glucuronide
Cat.No: T35939
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1051 Retinoic acid

维生素A酸,Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin

Retinoid Receptor; Endogenous Metabolite; PPAR; Autophagy Autophagy; DNA Damage/DNA Repair; Metabolism
Retinoic acid (Tretinoin) 是维生素 A 的代谢产物,是一种视黄酸受体 RAR 的天然激动剂,抑制 RARα/β/γ (IC50=14 nM)。Retinoic acid 可以诱导细胞分化、减少细胞增殖和抑制肿瘤发生。
T5657 Veratraldehyde

3,4-Dimethoxybenzaldehyde,藜芦醛

Antifungal Microbiology/Virology
Veratraldehyde (3,4-Dimethoxybenzaldehyde) 是一种能够使用于香料,农业化学和制药工业中的重要化学品。
T3364 Veratramine

NSC17821,黎芦碱,NSC23880,藜芦胺

Sodium Channel Membrane transporter/Ion channel
Veratramine (NSC-23880) 是一种信号转导抑制剂,可作用于肿瘤。
T8170 Carboxyatractyloside

羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt

Others Others
Carboxyatractyloside (Carboxyatractyloside tripotassium salt) tripotassium salt 是一种 ADP/ATP 载体蛋白 (ADP/ATP carrier) 抑制剂,抑制线粒体 ADP/ATP 的转运。它是一种具有毒性的天然产物,
TN1413 Atranorin

荔枝素,巴美灵,荔枝素

Endogenous Metabolite; NO Synthase; Ras GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
Atranorin 是地衣的次生代谢产物,具有显着的抗伤害、抗炎和氧化还原活性,对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
TN3340 Acetylatractylodinol

Tractylodinol acetate,乙酰基仓术呋喃烃醇

Others Others
Acetylatractylodinol (Tractylodinol acetate) 是分离自Atractylodes lancea 中,具有抗氧化作用。
T5S0167 Atractylenolide I

白术内酯 I,白术内酯I;苍术内酯I

IL Receptor; TNF; TLR; JAK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Atractylenolide I 是从白术根中得到的一种倍半萜烯,具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂,在 A375 细胞中,能够降低JAK2和STAT3的磷酸化水平。
TCS1372 Atraric acid

Phosphatase; Androgen Receptor Endocrinology/Hormones; Metabolism
Atraric acid 衍生物作为一种新的化学先导结构,用于作为 AR 拮抗剂的新型治疗化合物,可用于预防或治疗前列腺疾病。它以剂量依赖性方式抑制 PTP1B 活性,IC50 值为 51.5 uM,表明阿特拉酸具有治疗糖尿病的潜力。
T5S0168 Atractylenolide II

2-Atractylenolide,Asterolide,苍术内酯II

Apoptosis; ERK; p38 MAPK; Akt; STAT Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
Atractylenolide II (2-Atractylenolide) 是一种从白术干燥根茎分离的倍半萜类天然产物,具有抗增殖活性。
T3666 Atractylodin

苍术素,Atractydin

Lipid Metabolism
Atractylodin (Atractydin) 是一种Atractylodes lancea 和A. chinensis 的根茎中所含精油的活性成分。它是天然杀虫剂,能够抑制Tribolium castaneum 的活性。
T3902 Atractylenolide III

白术内酯 III,ICodonolactone,8β-Hydroxyasterolide

Apoptosis Apoptosis
Atractylenolide III (ICodonolactone) 是白术根茎主要成分,通过诱导细胞色素 c 的释放、上调 Bax 的表达和易位凋亡诱导因子,是治疗人肺癌的潜力。
T3791 Atractyloside A

AChR Neuroscience
Atractyloside A 是存在于一些植物中的贝壳杉类二萜糖苷,具有降血压、降血糖、抗肿瘤等活性。
T3S0156 Atractyloside potassium salt

Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐

Others Others
Atractyloside potassium salt (Atractyloside Dipotassium Salt) 是一种从苍术果实中分离出得到的二萜苷类化合物,具有毒性。它能抑制大鼠心脏线粒体膜的氯离子通道。它是高效、特异性的线粒体 ADP/ATP 转运 (ADP/ATP transport) 抑制剂。
TN3304 8beta-Methoxyatractylenolide I

Others Others
8beta-Methoxyatractylenolide I is a natural product from Atractylodes macrocephala.
TN6469 Biatractylolide

Biatractylolide has a neuroprotective effect on glutamate-induced injury in PC12 and SH-SY5Y cells through a mechanism of the PI3K-Akt-GSK3β-dependent pathways. The molecular mechanisms of inhibitory activities of biatractylolide on AChE are not only thro
T82634 Cynatratoside D

Cynatratoside D为从白黎芦醇根部分离提取的一种寡糖苷。
T34536 Satratoxin H

Satratoxin-H

Satratoxin H is an air- and food-borne mycotoxin, which has been implicated in human health damage.
TN3747 Cynatratoside A

Antifection Microbiology/Virology
Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis.
T3S0165 Atractylone

Atractylon,苍术酮

Others Others
Atractylone (Atractylon) 具有保肝、降血糖、抗菌、抗肿瘤、抗病毒等作用。
TN3468 Atractylochromene

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Atractylochromene is an inhibitor of β-catenin dependent Wnt pathway, it may be a potential chemotherapeutic agent for the prevention and treatment of human colon cancer.
T6S1315 Oroxylin A

千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮,具有较强的抗癌作用。

天然产物

Retinoic acid
Cat.No: T1051
Synonym: 维生素A酸,Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin
Target: Retinoid Receptor, Endogenous Metabolite, PPAR, Autophagy
Veratraldehyde
Cat.No: T5657
Synonym: 3,4-Dimethoxybenzaldehyde,藜芦醛
Target: Antifungal
Veratramine
Cat.No: T3364
Synonym: NSC17821,黎芦碱,NSC23880,藜芦胺
Target: Sodium Channel
Carboxyatractyloside
Cat.No: T8170
Synonym: 羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt
Target: Others
Atranorin
Cat.No: TN1413
Synonym: 荔枝素,巴美灵,荔枝素
Target: Endogenous Metabolite, NO Synthase, Ras
Acetylatractylodinol
Cat.No: TN3340
Synonym: Tractylodinol acetate,乙酰基仓术呋喃烃醇
Target: Others
Atractylenolide I
Cat.No: T5S0167
Synonym: 白术内酯 I,白术内酯I;苍术内酯I
Target: IL Receptor, TNF, TLR, JAK, STAT
Atraric acid
Cat.No: TCS1372
Synonym:
Target: Phosphatase, Androgen Receptor
Atractylenolide II
Cat.No: T5S0168
Synonym: 2-Atractylenolide,Asterolide,苍术内酯II
Target: Apoptosis, ERK, p38 MAPK, Akt, STAT
Atractylodin
Cat.No: T3666
Synonym: 苍术素,Atractydin
Target: Lipid
Atractylenolide III
Cat.No: T3902
Synonym: 白术内酯 III,ICodonolactone,8β-Hydroxyasterolide
Target: Apoptosis
Atractyloside A
Cat.No: T3791
Synonym:
Target: AChR
Atractyloside potassium salt
Cat.No: T3S0156
Synonym: Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐
Target: Others
8beta-Methoxyatractylenolide I
Cat.No: TN3304
Synonym:
Target: Others
Biatractylolide
Cat.No: TN6469
Synonym:
Target:
Cynatratoside D
Cat.No: T82634
Synonym:
Target:
Satratoxin H
Cat.No: T34536
Synonym: Satratoxin-H
Target:
Cynatratoside A
Cat.No: TN3747
Synonym:
Target: Antifection
Atractylone
Cat.No: T3S0165
Synonym: Atractylon,苍术酮
Target: Others
Atractylochromene
Cat.No: TN3468
Synonym:
Target: Wnt/beta-catenin
Oroxylin A
Cat.No: T6S1315
Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy
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