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60

抑制剂 & 化合物

10

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9264	ECBN HCL 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)	Others	Others
	ECBN HCL (A-30912A nucleus hydrochloride) 是一种 Echinocandin B 脱酰酶催化反应的产物。
T8459	DNQX disodium salt DNQX Disodium	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	DNQX disodium salt 是一种选择性、强竞争性的非 NMDA 谷氨酸受体 (non-NMDA glutamate receptor) 拮抗剂 (对 AMPA、kainate 和 NMDA 受体的 IC50分别为 0.5、2 和 40 μM)，是一种喹恶啉衍生物。
T7304	DNQX 二硝基喹酮,FG 9041	GluR; iGluR	Membrane transporter/Ion channel; Neuroscience
	DNQX (FG 9041) 是喹恶啉衍生物，是一种选择性和强竞争性的非 NMDA 谷氨酸受体拮抗剂，对 AMPA、kainate 和 NMDA 受体的IC50分别为 0.5、2 和 40 μM。
T11277	FG 7142 ZK 39106,LSU-65	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	FG 7142 (LSU-65) 是一种非选择性苯二氮卓类反向激动剂，对含 α1 亚基的 GABAA 受体具有高亲和力，Ki 为 91 nM。它还调节 GABA 诱导的 GABAA 受体上的氯离子通量，表达 α1 亚基，EC50为 137 nM。它可增加酪氨酸羟基化并导致小鼠大脑皮层中 β-肾上腺素受体的上调。
T4420	4-Hydroxytamoxifen ICI 79280,(Z)-4-hydroxy Tamoxifen,4-羟基他莫昔芬,trans-4-Hydroxytamoxifen	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	4-Hydroxytamoxifen (ICI 79280) 是 Tamoxifen 的活性代谢产物，是一种雌激素受体调节剂 (SERM)，具有选择性和口服有效性。4-Hydroxytamoxifen 具有抗肿瘤活性，可用于乳腺癌的研究。
T83651	AC-263093	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	AC-263093 是一种选择性 NPFFR2 激动剂，具有抗焦虑活性，可增加下丘脑室旁核中的c-Fos蛋白表达。
T12220	NIC3	Others	Others
	NIC3 是伏隔核相关蛋白 1 (NAC1) 的选择性抑制剂，与 NAC1 的保守位点 Leu-90 结合，阻止其同源二聚化，诱导蛋白酶体 NAC1 的降解。具有抗肿瘤作用。
T23854	Carbidine Carbidine dihydrochloride,Karbidin,Carbidin,Karbidine	Others	Others
	Carbidine (Carbidin) 是γ-carboline 的衍生物，一种非典型的抗精神病药物。它可以在体内和体外降低DA 对伏隔核突触体释放3H-DA 和酪氨酸羟化酶活性的抑制作用。
TP1653L	SV40 T-Ag-derived NLS peptide acetate SV40 T-Ag-derived NLS peptide acetate(105425-98-7 free base)	Others	Others
	SV40 T-Ag-derived NLS peptide acetate (SV40 T-Ag-derived NLS peptide acetate)(105425-98-7 free base) 是一种核定位信号肽。用这种肽标记的 DNA 可以有效地转移到细胞核中。
T1844	KPT330,(E)- (E)-RN,KPT-330,KPT330,KPT 330	Others; CRM1	Membrane transporter/Ion channel; Others
	(E)-RN (KPT 330) 是一种 CRM1 选择性核输出抑制剂。它抑制细胞核中的蛋白质运输并诱导间皮瘤细胞中的细胞周期停滞和凋亡。
T1127	Beclometasone dipropionate Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase	Glucocorticoid Receptor	Endocrinology/Hormones
	Beclometasone dipropionate (Vancenase) 是具有口服活性的糖皮质激素，具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物，Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
T2162	Maribavir BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Maribavir (GW257406X) 是一种可口服的苯并咪唑核苷化合物，具有抗巨细胞病毒的活性。
T10904	CWP232228	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	CWP232228 是一种高效的、选择性的Wnt/β-catenin 信号通路抑制剂，在细胞核中，拮抗 β-catenin 与 T 细胞因子结合。它能够抑制乳腺癌和肝癌干细胞的生长，抑制肿瘤的形成和转移，且没有毒性。
T64317	ZZL-7	Serotonin Transporter	Neuroscience
	ZZL-7是一种起效快的抗抑郁药。ZZL-7破坏中缝背核（DRN）神经元一氧化氮合酶（nNOS）和血清素转运蛋白（SERT）之间的相互作用。ZZL-7可以很容易地穿过血脑屏障。ZZL-7在重度抑郁症（MDD）中具有研究价值。
T16538	PIN1 inhibitor API-1	Others	Others
	PIN1 inhibitor API-1 是特殊的 Pin1抑制剂，可直接特异性地与 Pin1 肽基脯氨酰异构酶结构域结合，并抑制 Pin1 顺反异构活性。它保留 pXPO5 的活性构象，恢复 pXPO5 将前 miRNA 从细胞核转运到细胞质的能力，从而上调抗癌 miRNA 的生物发生，抑制体内外肝癌的发生。
T1666	Fludrocortisone acetate 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate	Glucocorticoid Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Fludrocortisone acetate (9α-Fludrocortisone acetate) 是一种合成的盐皮质激素，可减少尿液中钠丢失量，也用于增加血压，有用于阿狄森氏病的研究潜力。
T2548	Diflorasone	Glucocorticoid Receptor	Endocrinology/Hormones
	Diflorasone 是一种皮质类固醇激素受体激动剂，具有抗炎和免疫抑制作用。它可通过细胞膜扩散进入细胞，并与细胞质中的糖皮质激素受体结合。它用于研究湿疹、牛皮癣等皮肤病。
T19055	RT-NH2 Real Thiol-NH2	Others	Others
	RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus. It is a RealThiol prototype without the carboxylic acid groups.
T34963	TSPA
	TSPA is an ATF6α translocation inducer which effectively promotes ATF6α translocation into the nucleus and ameliorates glucose homeostasis on db/db mice.
T34903	TO-PRO3 iodide TOPRO3 iodide,TO-PRO3 iodide salt
	TO-PRO3 iodide is a nucleic acid stain that can stain the nucleus of cells in different states, including living, early apoptotic, and necrotic cells.
T71486	NS-0011
	NS-0011 is an inhibitor of CDK5 translocation which increases CDK5 accumulation in the nucleus, suppressing both cancer cell proliferation and xenograft tumorigenesis.
TP1653	SV40 T-Ag-derived NLS peptide
	This peptide, a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus.
T31016	Coumarin, 3-glyoxyloyl-8-methoxy- 3-Glyoxyloyl-8-methoxycoumarin,3-Glyoxyl-8-methoxycoumaric aldehyde
	Coumarin, 3-glyoxyloyl-8-methoxy- is a coumarin analogue for treatment of various diseases. Substituting new functional groups at different positions of coumarin nucleus may be useful in the development of novel compounds for the treatment of cancer.
T37667	True Blue
	True blue is a fluorescent neuronal retrograde tracer that labels the nucleus, nucleolus, cell body, proximal dendrites, and axons of neurons. It displays excitation/emission maxima of 373/404 nm, respectively.
T24693	QD325 QD 325,QD-325
	QD325 is a potent redox modulator for the Treatment of Pancreatic Ductal Adenocarcinoma. Nascent RNA sequencing following treatments with QD325 revealed induction of stress responses in the nucleus, endoplasmic reticulum, and mitochondria of pancreatic ca
T31015	Coumarin, 3-glyoxyloyl- 3-Glyoxylcoumaric aldehyde,3-Glyoxyloylcoumarin,Aldeide cumarin-3-gliossilica
	Coumarin, 3-glyoxyloyl-, is a coumarin analogue for treatment of various diseases. Substituting new functional groups at different positions of coumarin nucleus may be useful in the development of novel compounds for the treatment of cancer.
TP1830L	SV40 large T antigen NLS acetate	Others	Others
	SV40 large T antigen NLS acetate 是从大 T 抗原残基 47 到 55，使蛋白质进入细胞核。
TP2215	Agouti-related Protein (AGRP) (25-82), human	Others	Others
	Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalamus. The appetite-stimulating effect
TP2073	BigLEN(mouse) BigLEN (mouse)
	GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
T36024	FR179642 (hydrate) FR179642 (hydrate)
	FR179642 is the cyclic peptide nucleus of the lipopeptide antifungal FR901379 and an intermediate in the synthesis of the echinocandin antifungal FK463 .1,2 1.Tomishima, M., Ohki, H., Yamada, A., et al.FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activityJ. Antibiot. (Tokyo)52(7)674-676(1999) 2.Ueda, S., Shibata, T., Ito, K., et al.Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907J. Antibiot. (Tokyo)64(2)169-175(2011)
TP1520	Hepatitis B Virus Core (128-140) Hepatitis B Virus Core 128-140
	The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during the cell cycle.
T81698	NBD-LLLLpY
	NBD-LLLLpY Y为通过酶催化生成的核内肽，专门用于靶向毁灭人类诱导多能干细胞。
TP1830	SV40 large T antigen NLS
	SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
T38980	Mg(II) protoporphyrin IX
	Mg(II) protoporphyrin IX is a crucial compound in the synthesis of chlorophyll in Chlorella. It also serves as a negative regulator of nuclear photosynthetic gene expression. Additionally, Mg(II) protoporphyrin IX is employed as a valuable research tool for investigating the signaling molecule involved in plastid-to-nucleus communication.
T75963	Substance P(1-7) TFA
	Substance P(1-7) TFA，为神经肽P物质(SP)的一个片段，能对孤束核产生抑制和缓和效果。
TP2045	CH 275
	Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin release in the rat nucleus accumbens
T37150	ADTN hydrobromide
	ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM.
T37131	MS 15203
	Potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice. Wardman et al (2016) Identification of a small-molecule ligand that activates the neuropeptide receptor GP...
T70399	TTC-352
	TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells.
T26564	ADCI SGB-017,SGB017,SGB 017
	ADCI is an inhibitor of voltage-activated sodium channels and N-methyl-D-aspartate (NMDA)-receptor-gated channels. Inhibition of sodium channels by ADCI was voltage dependent. High doses of ADCI increased dopamine metabolism in the prefrontal cortex and/o
T12076L	ML218	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	ML218 是一种具有口服活性、选择性、高效性且可穿透血脑屏障的 T 型 Ca2+ 通道抑制剂（Cav3.2 和 Cav3.3 的 IC50 分别为 310 nM 和 270 nM）。ML218 可抑制丘脑下核（STN）神经元的突发性活动。
TP1542	26Rfa, Hypothalamic Peptide, human
	This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area.
T75915	CTOP TFA
	CTOP TFA为高效、高选择性μ-阿片受体(μ-opioid receptor)拮抗剂。其能拮抗吗啡引发的急性镇痛效果及运动能力增强，同时升高伏隔核外多巴胺水平，并呈剂量依赖性增强运动能力。
T27165	Diazaborine Diazaborine compound 2b18,Pkf 84.474,Pkf 84474,Pkf-84474,SA-84474
	Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of the protein from the nucleolus to t
T76301	Agouti-related Protein (AGRP) (83-132) Amide (human)
	Agouti-related Protein (AGRP) (83-132) Amide (human)，一种AGRP的片段，主要在下丘脑弓状核中表达。该化合物主要通过作为黑皮质素-4受体(MC4R)的反向激动剂来增加食物摄入。
T70956	JNJ-pan-AR
	JNJ-pan-AR, a meylated analogue of JNJ-63576253, is a novel pan-AR antagonist with potent activity against wild-type and clinically relevant AR mutations including F877L. JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically binds to both wild-type and certain mutant forms of AR, thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus.
T72646	Asperbisabolane L
	Asperbisabolane L 是一种倍半萜类化合物，通过抑制NF-κB 活化途径发挥抗炎活性。Asperbisabolane L 抑制NF-κB 从细胞质转移到细胞核。Asperbisabolane L 作用于 LPS 激活的 BV-2 小胶质细胞，还抑制 NO 产生。
T82885	BigLEN(mouse) TFA
	BigLEN(mouse) TFA 是一种GPR171激动剂，同时也是源自proSAAS的神经肽。该化合物调节小鼠的食物摄入，并且依赖于突触后G蛋白的激活，抑制谷氨酸释放到下丘脑室旁核的旁核细胞上。
T70987	AT-1001
	AT-1001 is an α3β4 nAChR partial agonist. AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats. AT-1001 also potently and reversibly blocks epibatidine-induced inward currents in HEK cells transfected with α3β4 nAChR. Importantly, AT-1001 potently and dose-dependently blocks nicotine self-administration in rats, without affecting food responding. When tested in a nucleus accumbens (NAcs) synaptosomal prepar...
T37435	PACAP-related Peptide (rat) (trifluoroacetate salt)	PACAP	GPCR/G Protein
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica...

化合物

Cat.No: T9264

Synonym: 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)

Target: Others

DNQX disodium salt

Cat.No: T8459

Synonym: DNQX Disodium

Target: NMDAR, iGluR

Cat.No: T7304

Synonym: 二硝基喹酮,FG 9041

Target: GluR, iGluR

Cat.No: T11277

Synonym: ZK 39106,LSU-65

Target: GABA Receptor

4-Hydroxytamoxifen

Cat.No: T4420

Synonym: ICI 79280,(Z)-4-hydroxy Tamoxifen,4-羟基他莫昔芬,trans-4-Hydroxytamoxifen

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T83651

Target: Neuropeptide Y Receptor

Cat.No: T12220

Target: Others

Cat.No: T23854

Synonym: Carbidine dihydrochloride,Karbidin,Carbidin,Karbidine

Target: Others

SV40 T-Ag-derived NLS peptide acetate

Cat.No: TP1653L

Synonym: SV40 T-Ag-derived NLS peptide acetate(105425-98-7 free base)

Target: Others

Cat.No: T1844

Synonym: (E)-RN,KPT-330,KPT330,KPT 330

Target: Others, CRM1

Beclometasone dipropionate

Cat.No: T1127

Synonym: Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase

Target: Glucocorticoid Receptor

Cat.No: T2162

Synonym: BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94

Target: Others, HCV Protease

Cat.No: T10904

Target: Wnt/beta-catenin

Cat.No: T64317

Target: Serotonin Transporter

PIN1 inhibitor API-1

Cat.No: T16538

Target: Others

Fludrocortisone acetate

Cat.No: T1666

Synonym: 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate

Target: Glucocorticoid Receptor, Autophagy

Cat.No: T2548

Target: Glucocorticoid Receptor

Cat.No: T19055

Synonym: Real Thiol-NH2

Target: Others

Cat.No: T34963

Cat.No: T34903

Synonym: TOPRO3 iodide,TO-PRO3 iodide salt

Cat.No: T71486

SV40 T-Ag-derived NLS peptide

Cat.No: TP1653

Coumarin, 3-glyoxyloyl-8-methoxy-

Cat.No: T31016

Synonym: 3-Glyoxyloyl-8-methoxycoumarin,3-Glyoxyl-8-methoxycoumaric aldehyde

Cat.No: T37667

Cat.No: T24693

Synonym: QD 325,QD-325

Coumarin, 3-glyoxyloyl-

Cat.No: T31015

Synonym: 3-Glyoxylcoumaric aldehyde,3-Glyoxyloylcoumarin,Aldeide cumarin-3-gliossilica

SV40 large T antigen NLS acetate

Cat.No: TP1830L

Target: Others

Agouti-related Protein (AGRP) (25-82), human

Cat.No: TP2215

Target: Others

Cat.No: TP2073

Synonym: BigLEN (mouse)

FR179642 (hydrate)

Cat.No: T36024

Synonym: FR179642 (hydrate)

Hepatitis B Virus Core (128-140)

Cat.No: TP1520

Synonym: Hepatitis B Virus Core 128-140

Cat.No: T81698

SV40 large T antigen NLS

Cat.No: TP1830

Mg(II) protoporphyrin IX

Cat.No: T38980

Substance P(1-7) TFA

Cat.No: T75963

Cat.No: TP2045

ADTN hydrobromide

Cat.No: T37150

Cat.No: T37131

Cat.No: T70399

Cat.No: T26564

Synonym: SGB-017,SGB017,SGB 017

Cat.No: T12076L

Target: Calcium Channel

26Rfa, Hypothalamic Peptide, human

Cat.No: TP1542

Cat.No: T75915

Cat.No: T27165

Synonym: Diazaborine compound 2b18,Pkf 84.474,Pkf 84474,Pkf-84474,SA-84474

Agouti-related Protein (AGRP) (83-132) Amide (human)

Cat.No: T76301

Cat.No: T70956

Asperbisabolane L

Cat.No: T72646

BigLEN(mouse) TFA

Cat.No: T82885

Cat.No: T70987

PACAP-related Peptide (rat) (trifluoroacetate salt)

Cat.No: T37435

Target: PACAP

Cat. No.	Product Name	Target	Signaling Pathways
T3849	Kinsenoside 金线莲苷,(+)-Kinsenoside	Apoptosis; Nrf2	Apoptosis; Immunology/Inflammation
	Kinsenoside ((+)-Kinsenoside) 是从金盏花属植物中分离得到的主要活性成分，以 Nrf2 依赖的方式保护髓核细胞在氧化应激下的生存能力，防止细胞凋亡、衰老和线粒体功能障碍。它显示出显着的抗肝毒性和抗炎活性。
T4104	Ophiopojaponin C 麦冬皂苷C,Ophiopogonin C	Others	Others
	Ophiopogonin C' pharmacological activities may be related to the substances in nucleus mainly.
T3S1692	Octahydrocurcumin	Anti-infection; NF-κB; Reactive Oxygen Species; ROS	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Octahydrocurcumin 是一种姜黄素的氢化衍生物，是姜黄素的代谢物。
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
T5S1805	5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮	Others; Virus Protease; PARP; Caspase; Nrf2	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Others; Proteases/Proteasome
	5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) 是一种Cudrania tricuspidata 的提取物，通过激活 Nrf2/ARE 信号对 6-OHDA 诱导的氧化应激和细胞凋亡发挥神经保护作用。它抑制 6-OHDA 诱导的 SH-SY5Y 细胞中活化的caspase-3，caspase-9以及切割的PARP 表达。
T1168	Desonide Tridesilon,地索奈德,Locapred,Prednacinolone	Glucocorticoid Receptor	Endocrinology/Hormones
	Desonide (Prednacinolone) 是一种非氟化皮质类固醇抗炎剂，能够作用于糖皮质激素受体。
T0798	Triamcinolone Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone	Glucocorticoid Receptor; COX	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Triamcinolone (Aristocort) 是一种皮质类固醇激素受体激动剂，也是一种合成的长效糖皮质激素，具有抗炎活性。
T6S1315	Oroxylin A 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy	Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮，具有较强的抗癌作用。
T39077	Aeruginosin 865
	Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp . Luke ová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Aeruginosin 865 has anti-inflammatory effect
TN6394	Alisol B acetate
	Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B aceta

天然产物

Cat.No: T3849

Synonym: 金线莲苷,(+)-Kinsenoside

Target: Apoptosis, Nrf2

Ophiopojaponin C

Cat.No: T4104

Synonym: 麦冬皂苷C,Ophiopogonin C

Target: Others

Octahydrocurcumin

Cat.No: T3S1692

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

5,7-Dihydroxychromone

Cat.No: T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Cat.No: T1168

Synonym: Tridesilon,地索奈德,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

Cat.No: T0798

Synonym: Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Cat.No: T6S1315

Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Aeruginosin 865

Cat.No: T39077

Alisol B acetate

Cat.No: TN6394

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