Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 686 | 35日内发货 | ||
25 mg | ¥ 2,970 | 35日内发货 | ||
50 mg | ¥ 5,440 | 35日内发货 |
产品描述 | ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM. |
体内活性 | In vivo, 6,7-ADTN induces hyperlocomotion in rats when injected bilaterally at a dose of 100 nmol per side into the nucleus accumbens. It increases cAMP production and glycoprotein secretion in the albumen gland of H. duryi (snail). It also reduces sucrose feeding in R. maderae (cockroach) nymphs. |
分子量 | 260.13 |
分子式 | C10H14BrNO2 |
CAS No. | 13575-86-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 100 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 3.8442 mL | 19.2212 mL | 38.4423 mL | 96.1058 mL |
5 mM | 0.7688 mL | 3.8442 mL | 7.6885 mL | 19.2212 mL | |
10 mM | 0.3844 mL | 1.9221 mL | 3.8442 mL | 9.6106 mL | |
20 mM | 0.1922 mL | 0.9611 mL | 1.9221 mL | 4.8053 mL | |
50 mM | 0.0769 mL | 0.3844 mL | 0.7688 mL | 1.9221 mL | |
100 mM | 0.0384 mL | 0.1922 mL | 0.3844 mL | 0.9611 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
ADTN hydrobromide 13575-86-5 ADTN Hydrobromide (±) 2 Amino 6,7 dihydroxy 1,2,3,4 tetrahydronaphthalene (hydrobromide) (±)2Amino6,7dihydroxy1,2,3,4tetrahydronaphthalene (hydrobromide) Inhibitor inhibitor inhibit