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60

抑制剂 & 化合物

12

天然产物

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Cat. No. Product Name Target Signaling Pathways
T7526 JNJ-17203212

TRP/TRPV Channel Membrane transporter/Ion channel
JNJ-17203212 是一种竞争性 TRPV1选择性拮抗剂。它被开发用于疼痛处理的研究。
T2587 Ecabet Sodium

TA-2711E,TA-2711,伊卡倍特钠

Reactive Oxygen Species; Antibacterial Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Ecabet Sodium (TA-2711) 可通过抑制活性氧的产生,促进幽门螺杆菌的根除,可用于胃肠道疾病的相关研究。
T22321 edetate calcium disodium

EDTA calcium disodium,乙二胺四乙酸二钠钙

Others Others
Edetate calcium disodium(EDTA calcium disodium) 是一种螯合剂,主要用于治疗严重的铅中毒。
T60010 BTT-266

Calcium Channel Membrane transporter/Ion channel; Metabolism
BTT-266 是一种电压门控钙通道阻滞剂,用于疼痛管理。
T0715 Chlormezanone

Trancopal,氯美扎酮,芬那露

Others; GABA Receptor Membrane transporter/Ion channel; Neuroscience; Others
Chlormezanone (Trancopal) 是一种非苯二氮卓类药物,用于治疗焦虑症和肌肉痉挛。
T21389 Enprofylline

Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum,恩丙茶碱

Others Others
Enprofylline (Enprofilina) 是具有选择性的 A2B 受体竞争性拮抗剂 (Ki:7 μM) ,也是磷酸二酯酶抑制剂。它可用于研究哮喘、慢性阻塞性肺疾病。
T40811 Eflornithine

RMI71782,α-difluoromethylornithine,DFMO,依氟乌氨酸,MDL71782

Eflornithine is an irreversible inhibitor that specifically targets the enzyme ornithine decarboxylase. It serves as a therapeutic medication for two conditions: the treatment of African trypanosomiasis and the management of excessive facial hair growth in women.
T8834 EST64454 hydrochloride

EST64454

Sigma receptor GPCR/G Protein
EST64454 hydrochloride (EST64454) 是一种可口服的选择性sigma-1受体拮抗剂,Ki 为 22 nM。它有用于疼痛的研究潜力。
T1081 Naftidrofuryl oxalate

萘呋胺酯 草酸盐,Nafronyl oxalate,Nafronyl oxalate salt

5-HT Receptor GPCR/G Protein; Neuroscience
Naftidrofuryl oxalate (Nafronyl oxalate) 是一种用于治疗外周和脑血管疾病的药物,可增加细胞氧化能力,也是一种 5-HT2 受体拮抗剂。
T21419 Diphenhydramine

苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Diphenhydramine (Syntedril) 是第一代具有抗胆碱能作用的H1 受体拮抗剂,它能透过血脑屏障。
T16472 Pericyazine

Propericiazine,氰噻嗪,RP 8909

Dopamine Receptor GPCR/G Protein; Neuroscience
Pericyazine (Propericiazine) 是第一代抗精神病药物,是一种选择性的 D2 多巴胺受体 (D2-dopamine receptor) 拮抗剂,具有肾上腺溶解、抗胆碱能和锥体外系作用,被用作短期管理严重焦虑状态和精神病的辅助药物。
T3141 Bendazac L-lysine

Bendazac lysine,Bendazaco lisina,苄达赖氨酸

Others Others
Bendazac L-lysine (Bendazaco lisina) 是一种能够控制白内障的药物。它可以保护患者的视力水平,延缓手术干预的需要。
T2397 Topiroxostat

托匹司他,FYX-051

P450; ROS; Xanthine Oxidase Immunology/Inflammation; Metabolism
Topiroxostat (FYX-051) 是一种有效的口服黄嘌呤氧化还原酶 (XOR) 抑制剂,IC50=5.3 nM,Ki=5.7 nM。它还表现出弱的CYP3A4抑制活性 (18.6%)。它有用于高尿酸血症的研究潜力。
T0712 Suloctidil

ATPase; Platelet aggregation Membrane transporter/Ion channel; Others
Suloctidil 是一种外周血管扩张剂,作用于大鼠脑突触, 影响Na+/ K+ ATP 酶活性和膜流动性,可治疗痴呆和血栓形成病症。
T1119 Rasagiline

雷沙吉兰,AGN1135,TVP1012

BCL; MAO; Monoamine Oxidase Apoptosis; Metabolism; Neuroscience
Rasagiline (AGN1135) 是不可逆的、高效的、选择性的线粒体单胺氧化酶 (MAO) 抑制剂,抑制大鼠脑 MAO B 和 MAO A 的 IC50分别为 4.43 nM 和 412 nM。
T1531 Mometasone furoate

糠酸莫美他松,糠酸莫米松,Sch32088

Glucocorticoid Receptor Endocrinology/Hormones
Mometasone furoate (Sch32088) 是糖皮质激素受体激动剂,具有抗炎和抗过敏作用。它是皮质固醇类试剂,动物模型中,可局部应用于气道炎症、慢性皮肤湿疹、哮喘。
T1179 Tiotropium bromide

Tiopropium,噻托溴铵,BA679 BR

AChR Neuroscience
Tiotropium bromide (BA679 BR) 是一种毒蕈碱乙酰胆碱受体拮抗剂,可阻断乙酰胆碱配体的结合。
T1551 Tegaserod maleate

HTF-919,马来酸替加色罗,SDZ-HTF-919

5-HT Receptor GPCR/G Protein; Neuroscience
Tegaserod maleate (SDZ-HTF-919) 是选择性5-HT4受体的部分激动剂和5-HT2B 受体的拮抗剂,用于治疗肠易激综合征和便秘。
T2530 Levosimendan

OR1259,OR1855,左西孟旦

Potassium Channel; PDE; Carbonic Anhydrase; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Levosimendan (OR1259) 是一种钙增敏剂,通过以钙依赖性方式与心肌肌钙蛋白 C 结合,增加肌细胞对钙的敏感性来发挥其作用,可治疗急性失代偿性充血性心力衰竭。
T20570 Labetalol

Apo-Labetalol,Albetol,Trandate,Dilevalol,拉贝洛尔,Normodyne

Adrenergic Receptor GPCR/G Protein; Neuroscience
Labetalol (Apo-Labetalol) 是一种抗高血压药物,可用于心血管疾病的研究,如妊娠期高血压。它是一种口服具有活性的选择性 α1- 和非选择性 β-肾上腺素能受体 (adrenergic receptor) 竞争性拮抗剂。
T1442 Pizotifen

Pizotyline,BC-105,苯噻啶

5-HT Receptor GPCR/G Protein; Neuroscience
Pizotifen (Pizotyline) 是5-HT2受体的有效拮抗剂,并对5-HT1C 有高亲和力。它是一种强血清素和色胺拮抗剂,具有较弱的抗胆碱能、抗组胺和抗激肽作用,还具有镇静和刺激食欲的特性。
T36184 Famoxadone

Famoxadone (DPX-JE874) is a widely utilized fungicide in Integrated Pest Management strategies for various agricultural crops, exhibiting broad-spectrum activity against an array of fungi[1].
T25848 Naftidrofuryl

Naftidrofuryl is used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be spasmolytic.
T18717 SPDV

Others Others
SPDV is a cleavable antibody-drug conjugate (ADC) linker utilized in the diagnostic and therapeutic management of cancer and B cell proliferative diseases.
T82735 Chlorthalidone impurity

Chlorthalidoneimpurity,作为Chlorthalidone的代谢物,该物质属于噻嗪类利尿剂,主要用于高血压的研究。
T21235 Alosetron

Lotronex,GR68755,GR-68755,GR 68755,阿洛司琼

Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.
T37913 Picoxystrobin

Picoxystrobin, a prominent primary strobilurin fungicide, is extensively utilized for efficient plant disease management. By obstructing electron transfer at the Qo center of cytochrome b and c1, picoxystrobin effectively halts mitochondrial respiration[1].
T70089 Colterol (free base)

Colterol (free base) is a short-acting β2-adrenoreceptor agonist. Bitolterol, a prodrug for colterol, is used in the management of bronchospasm in asthma and chronic obstructive pulmonary disease.
T38451 Clodinafop-propargyl

Clodinafop-propargyl, a prominent member of aryloxyphenoxy-propionate herbicides, is employed for postemergence management of annual grasses in cereals, such as Avena, Lolium, Setaria, Phalaris, and Alopecurus spp.
T69148 Colterol HCl

Colterol HCl is the salt form of Colterol (free base), a short-acting β2-adrenoreceptor agonist. Bitolterol, a prodrug for colterol, is used in the management of bronchospasm in asthma and chronic obstructive pulmonary disease.
T37959 GS-704277

GS-704277, an alanine metabolite derived from Remdesivir, a nucleoside analogue acknowledged for its potent antiviral efficacy, demonstrates remarkable effectiveness in vitro for the management of SARS-CoV-2 (COVID-19) infection[1][2].
T69152 Bromopride hydrochloride

Bromopride hydrochloride is the salt form of Bromopride, a dopamine D2 receptor blocker. Bromopride exerts is a gastrointestinal prokinetic exploited clinically for the management of motor disorders of the upper gastrointestinal tract, including functional dyspepsia, gastric stasis of various origins and emesis.
T80712 α-Glucosidase-IN-38

Glucosidase Metabolism
α-Glucosidase-IN-38 (Compound 11j) is an effective α-glucosidase inhibitor with an IC50 of 12.44±0.38 μM, playing a significant role in diabetes mellitus (DM).
T71758 Ambenonium chloride

Ambenonium Chloride is the chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereb...
T80540 TCMCB07

Melanocortin Receptor GPCR/G Protein; Neuroscience
TCMCB07为环状九肽,是具有口服活性及脑渗透性的黑皮质素受体4 (MC4R) 拮抗剂,在恶病质中具有关键作用。
T69158 Ambenonium chloride tetrahydrate

Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereb...
T35040 Vatiquinone

EPI-743,EPI743,alpha-Tocotrienol quinone. ATQ3,EPI 743

Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, optimizing metabolic control, enhanc
T79430 μ opioid receptor agonist 3

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
μopioid receptor agonist3 (compound 20) 是高效的μOR激动剂,其EC50 值为0.87 nM。该化合物在疼痛和神经精神适应症研究中具备潜在应用价值。
T81415 PPO-IN-3

PPO-IN-3(Compound 8ad)是一种高效的PPO抑制剂,具有0.67 nM的KI值,并表现出显著的芽后除草活性,主要用于杂草控制。
T81261 ROCK2-IN-7

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
ROCK2-IN-7是针对ROCK2的激酶抑制剂,能够抑制ROCK2/pSTAT3信号通路。该化合物在治疗银屑病模型中有着明显效果,通过抑制全身免疫激活,从而减轻炎症。
T32026 GYKI-13324

GYKI 13324,GYKI13324

GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. GYKI-13324 was studied on human colorectal tumor xenograft lines. Given orally in single or multiple daily doses, GYKI-13324 produced long-term or total regression of adenomatous, b
T62122 Chitinase-IN-5

Chitinase-IN-5 (8i) 是一种几丁质酶OfChi-h 的有效抑制剂 (IC50: 0.051 μM),具有良好的杀虫作用。Chitinase-IN-5 能够用于研究绿色害虫防治和管理。
T71157 Neladenoson dalanate

Neladenoson bialanate ; BAY-1067197,BAY-1067197,Neladenoson bialanate

Neladenoson dalanate (Neladenoson bialanate ; BAY-1067197) 是部分腺苷 A1 受体激动剂的前体,具有口服活性。Neladenoson dalanate 具有良好的药代动力学和安全性,可用于慢性心脏疾病的研究。
T33450 ML 23

ML-23,ML23

ML 23 is a melatonin analogue in the treatment and management of Parkinson's disease. ML-23 is a potential clinical candidate for the treatment of PD, and the present study has been undertaken to determine the efficacy of ML-23 in the 1-methyl-4-phenyl, 1
T76847 Imdevimab

Imdevimab (REGN10987) 是一种人的单克隆抗体,靶向导致 COVID-19 的SARS-CoV-2病毒。Imdevimab 对 COVID-19 变种缺乏疗效。Imdevimab 可与Casirivimab 联合使用,有效降低病毒载量,改善病症。
T78657 Azilsartan mepixetil potassium

QR-01019K

Azilsartan mepixetil potassium (QR-01019K),是一种高效安全的血管紧张素 II 受体拮抗剂,展现出卓越的持久降压效应以及显著且持续的降心率功能,有望用于治疗高血压、慢性心力衰竭和糖尿病肾病。
T61849 AM8936

AM8936 is a well-balanced and highly potent agonist for the cannabinoid receptor type-1 (CB1) in functional assays, with EC50 values of 8.6 nM and 1.4 nM for the rat CB1 (rCB1) and human CB1 (hCB1) receptors, respectively. It demonstrates a strong affinity for the rat CB1 receptor, exhibiting a K i value of 0.55 nM. In vivo studies have confirmed that AM8936 is a powerful and effective agonist for the CB1 receptor. Due to its therapeutic potential, AM8936 is particularly valuable for research fo...
T68663 GPI-15427

GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment...
T77037 Insulin efsitora alfa

Insulinefsitora alfa (LY-3209590) 为选择性胰岛素受体(IR)激动剂,该融合蛋白融合了人胰岛素受体(IR)激动剂与人免疫球蛋白G2(IgG2)的片段可结晶(Fc)结构域,分子量为64.1 kDa。Insulinefsitora alfa展现出良好的耐受性,并在糖尿病治疗中显示出潜在应用价值。
T37374 URB754

URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. There is evidence that the MAGL inhibitory activity of URB754 may be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial preparations. URB754 inhibits rat brain fa...

化合物

JNJ-17203212
Cat.No: T7526
Synonym:
Target: TRP/TRPV Channel
Ecabet Sodium
Cat.No: T2587
Synonym: TA-2711E,TA-2711,伊卡倍特钠
Target: Reactive Oxygen Species, Antibacterial
edetate calcium disodium
Cat.No: T22321
Synonym: EDTA calcium disodium,乙二胺四乙酸二钠钙
Target: Others
BTT-266
Cat.No: T60010
Synonym:
Target: Calcium Channel
Chlormezanone
Cat.No: T0715
Synonym: Trancopal,氯美扎酮,芬那露
Target: Others, GABA Receptor
Enprofylline
Cat.No: T21389
Synonym: Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum,恩丙茶碱
Target: Others
Eflornithine
Cat.No: T40811
Synonym: RMI71782,α-difluoromethylornithine,DFMO,依氟乌氨酸,MDL71782
Target:
EST64454 hydrochloride
Cat.No: T8834
Synonym: EST64454
Target: Sigma receptor
Naftidrofuryl oxalate
Cat.No: T1081
Synonym: 萘呋胺酯 草酸盐,Nafronyl oxalate,Nafronyl oxalate salt
Target: 5-HT Receptor
Diphenhydramine
Cat.No: T21419
Synonym: 苯海拉明,Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255
Target: Histamine Receptor
Pericyazine
Cat.No: T16472
Synonym: Propericiazine,氰噻嗪,RP 8909
Target: Dopamine Receptor
Bendazac L-lysine
Cat.No: T3141
Synonym: Bendazac lysine,Bendazaco lisina,苄达赖氨酸
Target: Others
Topiroxostat
Cat.No: T2397
Synonym: 托匹司他,FYX-051
Target: P450, ROS, Xanthine Oxidase
Suloctidil
Cat.No: T0712
Synonym:
Target: ATPase, Platelet aggregation
Rasagiline
Cat.No: T1119
Synonym: 雷沙吉兰,AGN1135,TVP1012
Target: BCL, MAO, Monoamine Oxidase
Mometasone furoate
Cat.No: T1531
Synonym: 糠酸莫美他松,糠酸莫米松,Sch32088
Target: Glucocorticoid Receptor
Tiotropium bromide
Cat.No: T1179
Synonym: Tiopropium,噻托溴铵,BA679 BR
Target: AChR
Tegaserod maleate
Cat.No: T1551
Synonym: HTF-919,马来酸替加色罗,SDZ-HTF-919
Target: 5-HT Receptor
Levosimendan
Cat.No: T2530
Synonym: OR1259,OR1855,左西孟旦
Target: Potassium Channel, PDE, Carbonic Anhydrase, Autophagy
Labetalol
Cat.No: T20570
Synonym: Apo-Labetalol,Albetol,Trandate,Dilevalol,拉贝洛尔,Normodyne
Target: Adrenergic Receptor
Pizotifen
Cat.No: T1442
Synonym: Pizotyline,BC-105,苯噻啶
Target: 5-HT Receptor
Famoxadone
Cat.No: T36184
Synonym:
Target:
Naftidrofuryl
Cat.No: T25848
Synonym:
Target:
SPDV
Cat.No: T18717
Synonym:
Target: Others
Chlorthalidone impurity
Cat.No: T82735
Synonym:
Target:
Alosetron
Cat.No: T21235
Synonym: Lotronex,GR68755,GR-68755,GR 68755,阿洛司琼
Target:
Picoxystrobin
Cat.No: T37913
Synonym:
Target:
Colterol (free base)
Cat.No: T70089
Synonym:
Target:
Clodinafop-propargyl
Cat.No: T38451
Synonym:
Target:
Colterol HCl
Cat.No: T69148
Synonym:
Target:
GS-704277
Cat.No: T37959
Synonym:
Target:
Bromopride hydrochloride
Cat.No: T69152
Synonym:
Target:
α-Glucosidase-IN-38
Cat.No: T80712
Synonym:
Target: Glucosidase
Ambenonium chloride
Cat.No: T71758
Synonym:
Target:
TCMCB07
Cat.No: T80540
Synonym:
Target: Melanocortin Receptor
Ambenonium chloride tetrahydrate
Cat.No: T69158
Synonym:
Target:
Vatiquinone
Cat.No: T35040
Synonym: EPI-743,EPI743,alpha-Tocotrienol quinone. ATQ3,EPI 743
Target:
μ opioid receptor agonist 3
Cat.No: T79430
Synonym:
Target: Opioid Receptor
PPO-IN-3
Cat.No: T81415
Synonym:
Target:
ROCK2-IN-7
Cat.No: T81261
Synonym:
Target: ROCK
GYKI-13324
Cat.No: T32026
Synonym: GYKI 13324,GYKI13324
Target:
Chitinase-IN-5
Cat.No: T62122
Synonym:
Target:
Neladenoson dalanate
Cat.No: T71157
Synonym: Neladenoson bialanate ; BAY-1067197,BAY-1067197,Neladenoson bialanate
Target:
ML 23
Cat.No: T33450
Synonym: ML-23,ML23
Target:
Imdevimab
Cat.No: T76847
Synonym:
Target:
Azilsartan mepixetil potassium
Cat.No: T78657
Synonym: QR-01019K
Target:
AM8936
Cat.No: T61849
Synonym:
Target:
GPI-15427
Cat.No: T68663
Synonym:
Target:
Insulin efsitora alfa
Cat.No: T77037
Synonym:
Target:
URB754
Cat.No: T37374
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3212 Digoxigenin

地谷新配基,异羟基洋地黄毒苷元

Others Others
Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases
TN6959 Tetradecane

Others Others
Tetradecane 是一种天然产物,可用于害虫防治研究。
TN2277 Torachrysone-8-O-b-D-glucoside

芦荟大黄素 8-葡萄糖甙,Torachrysone 8-O-glucoside

Antifection Microbiology/Virology
Torachrysone-8-O-b-D-glucoside 可从 Polygonum multiflorum 分离得到。它对 DPCs(真皮乳头细胞)的增殖具有促进作用。
T17303 α-Cyclodextrin

Alfadex,NSC269470,α-环糊精,NSC 269470,NSC-269470

Others Others
α-Cyclodextrin (Alfadex) 是一种多功能可溶性膳食纤维,可作为纤维原料销售。
T2S0731 Trilobatin

三叶苷,三叶甙,P-Phlorizin

Amylase Metabolism
Trilobatin (P-Phlorizin) 是源自Lithocarpus polystachyusRehd 的甜味剂,是一种HIV-1抑制剂,靶向 Gp41 包膜蛋白,具有神经保护作用。它还是SGLT1/2抑制剂,可选择性诱导人肝母细胞瘤细胞增殖。
T3874 Diosgenin glucoside

延龄草苷,地索苷,Disogluside,Trillin

Apoptosis; Others; Autophagy Apoptosis; Autophagy; Others
Diosgenin glucoside (Trillin) 是一种来自蒺藜的皂苷元类天然产物,可通过调节自噬和减轻细胞凋亡来保护脊髓免受损伤。它通过调节小胶质细胞 M1 极化提供神经保护,和其他具有类似活性的合成糖苷可用于治疗高胆固醇血症和动脉粥样硬化。
T22583 Arcaine sulfate

NMDAR Neuroscience
Arcaine sulfate 是一种多胺,是 N-甲基-d-天冬氨酸 (NMDA) 受体多胺结合位点的拮抗剂。 Arcaine 是一种胍丁胺类似物,与 ifenprodil 一起,可能有可能用于治疗癫痫疾病。
TN6337 Lupichromone

鲁冰花,5,7-Dihydroxy-6,8-diprenylchromone,5,7-二羟基-6,8-二异戊烯基色原酮

Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management.
T34611 Semduramicin

UK 61,689,Aviax,UK-61,689,UK61,689

Semduramicin is a carboxylic acid ionophore for management of chicken coccidiosis.
T34611L Semduramicin sodium

UK-61,689-2,UK 61,689-2,UK 61689-2,UK-61689-2,UK61689-2

Semduramicin sodium is a carboxylic acid ionophore for management of chicken coccidiosis.
TN2517 1,7-Dihydroxy-2,3-dimethoxyxanthone

Others Others
1,7-Dihydroxy-2,3-dimethoxyxanthone may have medicinal use in the management of inflammation, asthma and allergy, it antagonises in a non competitive but, reversible manner the contractions induced by chemical inflammatory mediators in the guinea pig trac
T73073 PTP1B-IN-21

PTP1B-IN-21 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.56 μM),抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP;IC50>100 μM),PTP1B 是抑制 2 型糖尿病的重要靶点。

天然产物

Digoxigenin
Cat.No: T3212
Synonym: 地谷新配基,异羟基洋地黄毒苷元
Target: Others
Tetradecane
Cat.No: TN6959
Synonym:
Target: Others
Torachrysone-8-O-b-D-glucoside
Cat.No: TN2277
Synonym: 芦荟大黄素 8-葡萄糖甙,Torachrysone 8-O-glucoside
Target: Antifection
α-Cyclodextrin
Cat.No: T17303
Synonym: Alfadex,NSC269470,α-环糊精,NSC 269470,NSC-269470
Target: Others
Trilobatin
Cat.No: T2S0731
Synonym: 三叶苷,三叶甙,P-Phlorizin
Target: Amylase
Diosgenin glucoside
Cat.No: T3874
Synonym: 延龄草苷,地索苷,Disogluside,Trillin
Target: Apoptosis, Others, Autophagy
Arcaine sulfate
Cat.No: T22583
Synonym:
Target: NMDAR
Lupichromone
Cat.No: TN6337
Synonym: 鲁冰花,5,7-Dihydroxy-6,8-diprenylchromone,5,7-二羟基-6,8-二异戊烯基色原酮
Target:
Semduramicin
Cat.No: T34611
Synonym: UK 61,689,Aviax,UK-61,689,UK61,689
Target:
Semduramicin sodium
Cat.No: T34611L
Synonym: UK-61,689-2,UK 61,689-2,UK 61689-2,UK-61689-2,UK61689-2
Target:
1,7-Dihydroxy-2,3-dimethoxyxanthone
Cat.No: TN2517
Synonym:
Target: Others
PTP1B-IN-21
Cat.No: T73073
Synonym:
Target:
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