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88

抑制剂 & 化合物

41

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T32164	Insect repellent M 3535
	Insect repellent M 3535 is a bug repellant.
T5637	Triflumuron	Others	Others
	Triflumuron 是一种杀虫剂，属于所谓的昆虫生长调节剂。它抑制昆虫幼虫合成甲壳素，导致死亡。
T81087	Stick Insect Hypertrehalosaemic Factor II
	Stick Insect Hypertrehalosaemic Factor II为合成肽，展现出与天然样品一致的FAB光谱、反相高效液相色谱特性以及生物活性，适用于高海藻糖效应的研究。
T8547	DCBA	Drug Metabolite	Metabolism
	DCBA 是驱虫剂 N-N-diethyl-meta-toluamide (DEET) 的代谢物。尿液中 DCBA 的浓度是评估 DEET 暴露程度的指标。
T16044	Methoprene 烯虫酯,ZR-515	Others	Others
	Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂，干扰昆虫的生命周期并阻止其成熟或繁殖。
T13536	Afoxolaner	Chloride channel; GABA Receptor; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Afoxolaner 是一种异恶唑啉杀虫剂/杀螨剂，可对抗犬的肩胛硬蜱。它作用于昆虫的 γ-氨基丁酸(GABA)受体谷氨酸受体，抑制 GABA 和谷氨酸调节的氯离子吸收，导致过度的神经元刺激和节肢动物死亡。
T16531	Picaridin 埃卡瑞丁,Lcaridin	Parasite	Microbiology/Virology
	Picaridin (Lcaridin) 是一种广谱节肢动物驱避剂，作用于蚊子和蜱的嗅觉感应，与其气味受体蛋白相互作用。
T4384	Halofenozide	Others	Others
	Halofenozide 是一种新的昆虫生长调节剂 (IGR)，具有苯甲酰肼结构，也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用，
T6488	Epinastine hydrochloride Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂，是一种可口服的选择性组胺 H1 受体拮抗剂，可抑制 IL-8 释放，具有抗过敏作用。
T67914	Insecticidal agent 364	mTOR; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Insecticidal agent 364是一种雷帕霉素激酶靶蛋白的选择性小分子抑制剂。Insecticidal agent 364具有抗肿瘤活性，通过抑制mTOR, Insecticidal agent 364旨在破坏参与癌细胞生长和存活的信号通路，从而潜在地抑制肿瘤生长。
T82065	Insecticidal agent 3
	Insecticidal agent 3 是一种昆虫生长调节剂 (IGRs)，特别针对 OfChtI, OfChtII 和 OfChi-h 的多几丁质酶抑制剂，Ki 值分别为 0.8 μM，11.9 μM 和 2.3 μM。该化合物通过扰乱正常生长和蜕皮过程，对两种鳞翅目害虫具有显著的杀虫活性。
T82064	Insecticidal agent 6	Parasite	Microbiology/Virology
	Insecticidal agent 6（化合物 Im）是昆虫兰尼碱受体（RyRs）的抑制剂，该化合物对 S. frugiperda RyRs 具有强效的抑制作用，其 EC50 值为0.6308 µM。该化合物在鳞翅目害虫中展现出卓越的杀虫效果，适用于病虫害研究。
T82066	Insecticidal agent 1
	Insecticidal agent 1 展示出比叶绿酮和川楝素更高的杀虫效力。
T79122	Insecticidal agent 2	Parasite	Microbiology/Virology
	Insecticidal agent 2 (example 2)为一种杀虫剂，展现对害虫的强效生长延迟效能。
T79762	Insecticidal agent 4
	4 (IA-8) 是一款针对分枝杆菌具有显著杀虫效果的芳基异恶唑啉衍生物。
T19821	Methoxyfenozide	Others	Others
	Methoxyfenozide 是一种二酰基肼类杀虫剂，其与鳞翅类蜕皮激素受体 (EcRs) 结合 (Kd=0.5 nM) 比对二萜 EcRs 结合 (Kd=124 nM) 的选择性高。
T20688L	Leucokinin I acetate Leucokinin I acetate(104600-89-7 Free base)	Others	Others
	Leucokinin I acetate 是一种抗昆虫肌肽的抗血清。
T0731	Diethyltoluamide N,N-Diethyl-m-toluamide,避蚊胺,DEET,N,N-Diethyl-meta-toluamide,Delphene,避蚊胺（DEET）	AChE; Parasite	Microbiology/Virology; Neuroscience
	Diethyltoluamide (DEET) 是驱虫剂中常见的活性成分，可保护皮肤，防止蚊虫叮咬。
T5560	Dicyclanil	Others	Others
	Dicyclanil 是一种化学结构与环丙嗪相似的昆虫生长调节剂。
T9751	Transfluthrin	Others	Others
	Transfluthrin 是一种挥发性拟除虫菊酯类杀虫剂，针对昆虫电压门控钠通道 (VGSC)。
T20137	Dimethoate Rogor,Phosphamid,Lurgo,L395,乐果,L 395,L-395	Others	Others
	Dimethoate (L-395) 是一种系统性和接触性杀虫剂，用于控制牛蛴螬和农场动物的某些其他害虫。
T3496	Buprofezin 噻嗪酮,NNI 750,Applaud,Buprofezine	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Buprofezin (Applaud) 是一种杀虫剂，通过抑制几丁质合成起作用，在体外还可以剂量依赖性地增加活性氧的产生。
T60023	CL-278474	Others	Others
	CL-278474 (化合物 I-79) 是有效的 β-N- 乙酰己糖氨基酶 OfHex1 抑制剂。
T0711L	Niclosamide olamine Niclosamide-olamine,Niclosamide Ethanolamine salt	Antibiotic; STAT; Parasite; Autophagy	Autophagy; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Niclosamide olamine (Niclosamide Ethanolamine salt) 是一种驱虫剂，可破坏寄生虫和动物模型中的线粒体代谢。它可逆地抑制雷帕霉素复合物的哺乳动物靶标，从而抑制STAT3(IC50为 0.25 μM) 并刺激自噬反应。
T22928L	Locustatachykinin I acetate	Others	Others
	Locustachykinin I acetate 是 Lacanobia 中脱酰胺酶的底物。它是一种从飞蝗中分离的昆虫速激肽相关肽。
T10618	Broflanilide	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Broflanilide 是昆虫抗狄氏剂 GABA 受体拮抗剂，可代谢为 Desmethyl-Broflanilide，抑制斜纹夜蛾 RDL GABAR，IC50值为 1.3 nM。
T19822	RH-5849 RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine	Others	Others
	RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) 是一种新型昆虫生长调节剂，可用作控制橄榄果蝇的潜在杀虫剂。
T10347L	Apidaecin IB acetate Apidaecin IB acetate (123276-94-8 Free base)	Others	Others
	Apidaecin IB acetate 是一种昆虫抗菌肽。 apidaecin IB acetate 对大肠杆菌（大肠杆菌 ML35、o18k1h7 和 ATCC 25922）的有效浓度为 8 μM。
T7124	Dinotefuran MTI-446,呋虫胺	Others; AChR; Parasite	Microbiology/Virology; Neuroscience; Others
	Dinotefuran (MTI-446) 是一种新型烟碱类杀虫剂, 通过抑制烟碱乙酰胆碱受体而破坏昆虫的神经系统起作用。
T19735	Flucycloxuron 氟螨脲,(E)-flucycloxuron,Andalin	Others	Others
	Flucycloxuron ((E)-flucycloxuron) 是一种甲壳素合成抑制剂，用作杀虫剂。在昆虫模型中，该抑制剂已被证明会影响几种生殖事件，例如产卵前的持续时间。
T11307	Fluxametamide 4-[5-(3,5-二氯苯基)-4,5-二氢-5-(三氟甲基)-3- 异恶唑基]-N-[(甲氧基氨基)亚甲基]-2-甲基苯甲酰胺	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Fluxametamide 是广谱杀虫剂，是 GABA-和谷氨酸门控氯离子通道拮抗剂，对 M. domestica 中 GABACl 和 GluCl 的IC50值分别为 1.95 和 225  nM。
T60127	Chlorantraniliprole Rynaxypyr,Chlorantranilipole,Rynaxpyr	Others	Others
	Chlorantraniliprole (Rynaxypyr) 是一种杀虫剂，能够有效地、选择性地激活鱼尼丁受体 (ryanodine receptor)，对黑腹果蝇和烟芽夜蛾的 ryanodine 受体 EC50 值分别为 40 nM 和 50 nM，对其选择性是对小鼠骨骼肌 2C12 细胞 ryanodine 受体 (EC50，14 μM) 的 300 多倍。
T38272	Thiacloprid	AChR; Parasite	Microbiology/Virology; Neuroscience
	Thiacloprid 属于氯烟碱类杀虫剂，主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性，通过疏水或氢相互作用，结合到小沟槽中，改变 DNA 的结构和稳定性。
T2196	Fipronil 氟虫腈,Fluocyanobenpyrazole,Termidor	P450; GluCls; GABA Receptor	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	Fipronil (Fluocyanobenpyrazole) 是昆虫GABA 受体的选择性拮抗剂，可抑制蟑螂神经元中谷氨酸盐引起的脱敏和非脱敏。在分离的大鼠肝微粒体中，它诱导细胞色素 P450 (CYP) 亚型CYP1A1/2、CYP2B1/2和CYP3A1/2的活性。
T0910	Terpin hydrate Terpin Monohydrate,cis-Terpin hydrate,萜品(水合结晶)	Others	Others
	Terpin hydrate 是一种祛痰药，可除去急慢性支气管炎病人的黏液。
T27691	JNJ-DGAT2-A JNJDGAT2A	Transferase	Metabolism
	JNJ-DGAT2-A 是 DGAT2 的特异性抑制剂（IC50 = 0.14 μM），可用于甘油三酯合成的研究。
T27339	Fluazuron Acatak
	Fluazuron is an insect growth regulator.
T31182	Dacrysterone
	Dacrysterone is an insect ecdysis hormone, also a newphytoecdysone.
T20807	Looplure ENT 33266,Pherocon CL,AI3-33266,Cabblemone,(Z)-7-Dodecen-1-olacetate
	Looplure is a chemosterilant, insect attractant and repellent.
T10788	Chitinase-IN-2	Others	Others
	Chitinase-IN-2 is an insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide.
T32117	Hydroprene
	Hydroprene is an insect growth regulator.
T21154	Chlorfluazuron IKI 7899,AI3-29785,CCRIS 2680,CGA 112913,Atabron
	Chlorfluazuron, a chitin synthesis inhibitor, is commonly used as an insect growth regulator for controlling the major insect pests in crops.
T71414	Litophynin A
	Litophynin A is an insect Growth Inhibitory Diterpenoids from the Soft Coral Litophyton sp.
T32519	Lac dye
	Lac dye is a possible food coloring agent which is completely nontoxic at low doses; lac dye is water soluble constituent of stick lac (commercial lac resin); lac resin is hardened secretion of insect Laccifer lacca (lac insect).
T26538	AC-24,055 AC24,055,AC 24,055,AC-24055,AC24055,AC 24055
	AC-24,055 is a synthetic insect feeding repellent.
T10787	Chitinase-IN-1	Others	Others
	Chitinase-IN-1 is an insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide.
T25904	OX3a OX-3a,OX 3a
	OX3a is an orco antagonist agent that acts by inhibiting odorant activation of insect Ors.
T36876	SBP1
	Human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication). Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.
T40613	Butopyronoxyl
	Butopyronoxyl is an insect repellent that can be mainly used to repel mosquitoes.
T71312	Litophynin C
	Litophynin C is an Insect Growth Inhibitory Diterpenoid from a Soft Coral Litophyton sp.

化合物

Insect repellent M 3535

Cat.No: T32164

Cat.No: T5637

Target: Others

Stick Insect Hypertrehalosaemic Factor II

Cat.No: T81087

Cat.No: T8547

Target: Drug Metabolite

Cat.No: T16044

Synonym: 烯虫酯,ZR-515

Target: Others

Cat.No: T13536

Target: Chloride channel, GABA Receptor, Parasite

Cat.No: T16531

Synonym: 埃卡瑞丁,Lcaridin

Target: Parasite

Cat.No: T4384

Target: Others

Epinastine hydrochloride

Cat.No: T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

Target: 5-HT Receptor, Histamine Receptor

Insecticidal agent 364

Cat.No: T67914

Target: mTOR, Autophagy

Insecticidal agent 3

Cat.No: T82065

Insecticidal agent 6

Cat.No: T82064

Target: Parasite

Insecticidal agent 1

Cat.No: T82066

Insecticidal agent 2

Cat.No: T79122

Target: Parasite

Insecticidal agent 4

Cat.No: T79762

Methoxyfenozide

Cat.No: T19821

Target: Others

Leucokinin I acetate

Cat.No: T20688L

Synonym: Leucokinin I acetate(104600-89-7 Free base)

Target: Others

Diethyltoluamide

Cat.No: T0731

Synonym: N,N-Diethyl-m-toluamide,避蚊胺,DEET,N,N-Diethyl-meta-toluamide,Delphene,避蚊胺（DEET）

Target: AChE, Parasite

Cat.No: T5560

Target: Others

Cat.No: T9751

Target: Others

Cat.No: T20137

Synonym: Rogor,Phosphamid,Lurgo,L395,乐果,L 395,L-395

Target: Others

Cat.No: T3496

Synonym: 噻嗪酮,NNI 750,Applaud,Buprofezine

Target: Reactive Oxygen Species

Cat.No: T60023

Target: Others

Niclosamide olamine

Cat.No: T0711L

Synonym: Niclosamide-olamine,Niclosamide Ethanolamine salt

Target: Antibiotic, STAT, Parasite, Autophagy

Locustatachykinin I acetate

Cat.No: T22928L

Target: Others

Cat.No: T10618

Target: GABA Receptor

Cat.No: T19822

Synonym: RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine

Target: Others

Apidaecin IB acetate

Cat.No: T10347L

Synonym: Apidaecin IB acetate (123276-94-8 Free base)

Target: Others

Cat.No: T7124

Synonym: MTI-446,呋虫胺

Target: Others, AChR, Parasite

Cat.No: T19735

Synonym: 氟螨脲,(E)-flucycloxuron,Andalin

Target: Others

Cat.No: T11307

Synonym: 4-[5-(3,5-二氯苯基)-4,5-二氢-5-(三氟甲基)-3- 异恶唑基]-N-[(甲氧基氨基)亚甲基]-2-甲基苯甲酰胺

Target: GABA Receptor

Chlorantraniliprole

Cat.No: T60127

Synonym: Rynaxypyr,Chlorantranilipole,Rynaxpyr

Target: Others

Cat.No: T38272

Target: AChR, Parasite

Cat.No: T2196

Synonym: 氟虫腈,Fluocyanobenpyrazole,Termidor

Target: P450, GluCls, GABA Receptor

Cat.No: T0910

Synonym: Terpin Monohydrate,cis-Terpin hydrate,萜品(水合结晶)

Target: Others

Cat.No: T27691

Synonym: JNJDGAT2A

Target: Transferase

Cat.No: T27339

Synonym: Acatak

Cat.No: T31182

Cat.No: T20807

Synonym: ENT 33266,Pherocon CL,AI3-33266,Cabblemone,(Z)-7-Dodecen-1-olacetate

Cat.No: T10788

Target: Others

Cat.No: T32117

Cat.No: T21154

Synonym: IKI 7899,AI3-29785,CCRIS 2680,CGA 112913,Atabron

Cat.No: T71414

Cat.No: T32519

Cat.No: T26538

Synonym: AC24,055,AC 24,055,AC-24055,AC24055,AC 24055

Cat.No: T10787

Target: Others

Cat.No: T25904

Synonym: OX-3a,OX 3a

Cat.No: T36876

Cat.No: T40613

Cat.No: T71312

Cat. No.	Product Name	Target	Signaling Pathways
T11680	Isoasatone A	P450	Metabolism
	Isoasatone A 是一种具有抗虫作用的天然产物，分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶，产生抗S. litura 作用。
TN1402	Arjungenin 阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸	Antifection; Immunology/Inflammation related	Immunology/Inflammation; Microbiology/Virology
	Arjungenin, a triterpene derived from Terminalia arjuna, exhibits insect feeding-deterrent and growth inhibitory properties.
T40878	Bombykol Hexadeca-10E,12Z-dien-1-ol,蚕蛾醇,(10E,12Z)-hexadeca-10,12-dien-1-ol,10E,12Z-hexadecadien-1-ol,Isobombycol	Others	Others
	Bombykol (Isobombycol) 是一种昆虫性信息素，是为 Bombyx mori 的雌性生产的性吸引剂。
T0845	Cyromazine CGA-72662,Cyromazin,环丙氨嗪	Others; Endogenous Metabolite	Metabolism; Others
	Cyromazine (CGA-72662) 是三聚氰胺的环丙基衍生物，是昆虫生长调节剂，用作杀虫剂和杀螨剂，通过影响某些昆虫幼虫阶段的神经系统而起作用。
T3240	Citronellol dihydrogeraniol,香茅醇,β-香茅醇,(±)-β-Citronellol	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Citronellol ((±)-β-Citronellol) 是一种单萜类化合物，从头状天竺葵中分离到。它可通过上调 TNF-α，RIP1/RIP3 的活性，下调 caspase-3/caspase-8 的活性，以及增加活性氧 (ROS) 的聚集来诱导肿瘤细胞的坏死性凋亡。
T5548	Verbenone 2-Pinen-4-one,马鞭草烯醇,(-)-Verbenone,马鞭草酮	Others	Others
	(-)-Verbenone ((-)-Verbenone) 是一种存在于 Suregada zanzibariensisVerdc 的树叶中的天然的萜烯。Verbenone 具有抗聚集信息素作用，可中断树皮甲虫对其聚集信息素的吸引。
TN6993	Benzylideneacetone Benzalacetone	Phospholipase; Endogenous Metabolite	Metabolism
	Benzylideneacetone 是由昆虫致病细菌 Xenorhabdus nematophila 产生的单萜类化合物，是磷脂酶A2（PLA2）抑制剂，对类花生酸生物合成具有抑制作用，可增强小菜蛾木霉菌的杆状病毒致病性。
T8076	cis-Jasmone 茉莉酮,Jasmone,顺式茉莉酮	Others	Others
	cis-Jasmone 是一种来源于植物中的天然产物。它由许多花组成型释放，有时通过叶子作为传粉者的引诱剂或作为昆虫花食草动物宿主定位的化学提示。它处理作物可以诱导对食草动物的直接防御，并能够释放吸收天敌的挥发性化合物来诱导间接防御。
TN6835	(E)-β-Farnesene (6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene,trans-β-Farnesene	Antifungal	Microbiology/Virology
	(E)-β-Farnesene (trans-β-Farnesene) 是一种存在于 Phlomis aurea Decne中的倍半萜烃，是许多蚜虫报警信息素的主要成分，可中断蚜虫摄食。(E)-β-Farnesene 通过破坏昆虫激素平衡来损害 Chilo suppressalis 幼虫的发育和存活。
T9076	Spinosad	Others	Others
	Spinosad 是在土壤细菌 S. spinosa 中发现的一种杀虫剂，是大环内酯多杀菌素 A 和多杀菌素 D 的混合物，可作为昆虫烟碱乙酰胆碱酯酶受体 (nAChRs) 的激动剂。它具有优良的环境和哺乳动物毒理学特征，以及杀灭幼虫的活性。
T9279	nerolidol acetate	Others	Others
	Nerolidol acetate是一种具有抗癌、抗炎、抗菌和抗虫的活性的天然倍半萜。Nerolidol acetate可抑制寄生虫活动，抑制吸血虫病、线虫病以及疟疾等。Nerolidol acetate可保护细胞免受脂质、蛋白质和 DNA 的氧化损伤，对小鼠海马神经细胞具有保护作用。
T3746	Dimethyl phthalate 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯	Others	Others
	Dimethyl phthalate (Fermine) 是一种邻苯二甲酸酯 (PAEs)，是一种已知的内分泌干扰物，也是一种普遍存在的污染物。它常作为增塑剂，赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。
T16791	Rottlerin Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525	CaMK; Apoptosis; Others; HIV Protease; PKA; PKC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Neuroscience; Others; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Rottlerin (NSC-56346) 是一种从Mallotus Philippinensis 中得到的天然产物，是 PKC 的特异性抑制剂，抑制HIV-1整合和狂犬病病毒感染。它通过活化 caspase 3 诱导细胞凋亡.
T13503	31-Norlanostenol	Others	Others
	31-Norlanostenol is a triterpene isolated from the latex of Euphorbia officinarum. It can act as an efficient insect growth regulator on S. frugiperda and Tenebrio molitor.
T40582	α-Farnesene
	α-Farnesene, a sesquiterpene, is a herbivore-induced plant volatile (HIPV) that plays a significant role in insect resistance across various plant species.
TN4990	Seneganolide	Antifection	Microbiology/Virology
	Seneganolide has insect antifeeding activity. Seneganolide A has antifungal activity.
T24175	Xanthumin
	Xanthumin is a naturally occurring insect development inhibitor against Drosophila melanogaster. Xanthumin is also an antibacterial compound.
T32326	Juvabione
	Juvabione is the methyl ester of todomatuic acid, both of which are sesquiterpenes (C15) found in the wood of true firs of the genus Abies. They exist as part of a mixture of sesquiterpenes based on the bisabolane scaffold. Sesquiterpenes of this family,
TN3159	6-Deoxy-9alpha-hydroxycedrodorin	Others	Others
	6-Deoxy-9alpha-hydroxycedrodorin shows potential value in the selection of insect-resistant clones for timber plantations.
TN4926	Rubrosterone	Others	Others
	Rubrosterone is an insect-molting C19-steroid.
TN1401	Arjunetin	Others	Others
	Arjunetin, an insect feeding-deterrent and growth inhibitor, shows antioxidant and anti-inflammatory activities.
T83545	(E)-(-)-Aspongopusamide B
	(E)-(-)-Aspongopusamide B (Compound 9) 是从昆虫Aspongopus chinensis 分离得到的一种天然产物。
T13449	(R)-(+)-Citronellal (+)-Citronellal,(R)-(+)-香茅醛	Others	Others
	(R)-(+)-Citronellal is a natural product isolated from citrus,used for insect repellent and antifungal properties.
TN4254	Inokosterone	Others	Others
	Inokosterone is an analgesic drug. It also shows high insect moulting hormone activity.
TN2306	Wilfordine	ATPase; Potassium Channel; Sodium Channel	Membrane transporter/Ion channel
	Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TN4403	Lactupicrin	Antifection	Microbiology/Virology
	Lactupicrin has antimicrobial and anti-cancer effects, it also protect the plant from insect feeding.
T83242	7-Hydroxy-5-methoxycoumarin
	7-Hydroxy-5-methoxycoumarin为间苯三酚类呋喃香豆素化合物，具备显著的天然昆虫拒食活性。
TN2287	Turkesterone	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions.
TN4795	Piperenone	PAFR	GPCR/G Protein
	Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.
T11009	Destruxin B	Others	Others
	Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through the Bcl-2 family-dependent mitochond
TN2727	Jatrophane 2	P-gp; Antifection	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera). Jatrophane 2 also demonstrates the mo
TN2723	Jatrophane 3	Antifection	Microbiology/Virology
	(2R,3R,4S,5R,7S,8S,9S,l3S,14S,15R)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R,3R, 4S,5R,7S,8S,9S,l3S,14S,15R)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene(Jatrophane 3) exhibit significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with EC50 values of 0.36 and 0.43 ug/cm2, respectively...
T83437	18-O-Demethylpederin
	18-O-Demethylpederin 是 pederin 的一种类似物，原先自隐翅虫科昆虫中分离得到。作为一种天然聚酮化合物，pederin 是非蛋白质昆虫毒素，展现了包含抗菌、抗病毒和抗肿瘤在内的广泛生物活性。
T83440	17-Hydroxyjolkinolide A Caudicifolin,Fischeriana A
	17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) 是一种从大戟根中提取的昆虫摄食抑制剂。它能有效诱导玉米夜蛾 (S. zeamais) 与赤霉成虫 (T. castaneum) 对谷物产生拒食行为，其EC50s 值分别为 631.9 ppm 和 656.5 ppm。
TN5228	Vestitol	Antifection	Microbiology/Virology
	Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemica...
T79985	Cryptosporioptide A	Phosphatase	Metabolism
	Cryptosporioptide A (Compound 3)是一种从昆虫寄生真菌Cordyceps gracilioides中分离出的色素蛋白酪氨酸磷酸酶抑制剂，针对PTP1B、SHP2、CDC25B、LAR和SHP1等酶展示了抑制作用，其IC50值分别为7.3、5.7、7.6、>50、4.9 μg/mL。
TN4659	Nimbin	COX	Immunology/Inflammation; Neuroscience
	Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect
TN2728	Jatrophane 4	Antifection	Microbiology/Virology
	(2R,3R,4S,5R,7S,8S,9S,l3S,14S,15R)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R,3R, 4S,5R,7S,8S,9S,l3S,14S,15R)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobut
TN4223	Homopterocarpin	Antifection	Microbiology/Virology
	Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...
T37609	(rel)-Asperparaline A
	Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces...

天然产物

Cat.No: T11680

Target: P450

Cat.No: TN1402

Synonym: 阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸

Target: Antifection, Immunology/Inflammation related

Cat.No: T40878

Synonym: Hexadeca-10E,12Z-dien-1-ol,蚕蛾醇,(10E,12Z)-hexadeca-10,12-dien-1-ol,10E,12Z-hexadecadien-1-ol,Isobombycol

Target: Others

Cat.No: T0845

Synonym: CGA-72662,Cyromazin,环丙氨嗪

Target: Others, Endogenous Metabolite

Cat.No: T3240

Synonym: dihydrogeraniol,香茅醇,β-香茅醇,(±)-β-Citronellol

Target: Reactive Oxygen Species

Cat.No: T5548

Synonym: 2-Pinen-4-one,马鞭草烯醇,(-)-Verbenone,马鞭草酮

Target: Others

Benzylideneacetone

Cat.No: TN6993

Synonym: Benzalacetone

Target: Phospholipase, Endogenous Metabolite

Cat.No: T8076

Synonym: 茉莉酮,Jasmone,顺式茉莉酮

Target: Others

(E)-β-Farnesene

Cat.No: TN6835

Synonym: (6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene,trans-β-Farnesene

Target: Antifungal

Cat.No: T9076

Target: Others

nerolidol acetate

Cat.No: T9279

Target: Others

Dimethyl phthalate

Cat.No: T3746

Synonym: 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯

Target: Others

Cat.No: T16791

Synonym: Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

31-Norlanostenol

Cat.No: T13503

Target: Others

Cat.No: T40582

Cat.No: TN4990

Target: Antifection

Cat.No: T24175

Cat.No: T32326

6-Deoxy-9alpha-hydroxycedrodorin

Cat.No: TN3159

Target: Others

Cat.No: TN4926

Target: Others

Cat.No: TN1401

Target: Others

(E)-(-)-Aspongopusamide B

Cat.No: T83545

(R)-(+)-Citronellal

Cat.No: T13449

Synonym: (+)-Citronellal,(R)-(+)-香茅醛

Target: Others

Cat.No: TN4254

Target: Others

Cat.No: TN2306

Target: ATPase, Potassium Channel, Sodium Channel

Cat.No: TN4403

Target: Antifection

7-Hydroxy-5-methoxycoumarin

Cat.No: T83242

Cat.No: TN2287

Target: Calcium Channel

Cat.No: TN4795

Target: PAFR

Cat.No: T11009

Target: Others

Cat.No: TN2727

Target: P-gp, Antifection

Cat.No: TN2723

Target: Antifection

18-O-Demethylpederin

Cat.No: T83437

17-Hydroxyjolkinolide A

Cat.No: T83440

Synonym: Caudicifolin,Fischeriana A

Cat.No: TN5228

Target: Antifection

Cryptosporioptide A

Cat.No: T79985

Target: Phosphatase

Cat.No: TN4659

Target: COX

Cat.No: TN2728

Target: Antifection

Homopterocarpin

Cat.No: TN4223

Target: Antifection

Cat.No: T35779

(rel)-Asperparaline A

Cat.No: T37609

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