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41

抑制剂 & 化合物

14

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Cat. No. Product Name Target Signaling Pathways
T80994 Therapeutic agent-1

Therapeutic agent-1 是一种杂芳基化合物,用于戈谢病的葡萄糖脑苷脂酶活性酶替代疗法。
T9340 1-phenyl-3,4-dihydroisochinoline

3,4-Dihydro-1-phenylisoquinoline,1-苯基-3,4-二氢异喹啉

Others Others
1-phenyl-3,4-dihydroisochinoline (3,4-Dihydro-1-phenylisoquinoline) 是神经递质多巴胺的结构类似物,与中枢神经系统中的多巴胺受体相互作用。它已被研究为治疗帕金森病、阿尔茨海默病和亨廷顿舞蹈症等神经疾病的潜在治疗剂。
T16345 NS13001

N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine

Potassium Channel Membrane transporter/Ion channel
NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) 是口服有效的 SK 通道选择性正向变构调节剂。NS13001 对 SK2 和 SK3 通道的 EC50分别为 1.8 μM 和 0.14 μM。NS13001 在脊髓小脑共济失调 2 型和其他小脑共济失调方面具有研究价值。
T50023 PDE4-IN-20

Others Others
ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 又称 EAPT,是一种有效的选择性 PDE4抑制剂,调节细胞内环腺苷酸(cAMP)水平。它已被用于多种科研应用,包括 cAMP 介导的信号转导通路的研究,并有潜力作为治疗炎症和免疫相关疾病的药物。
T19367 Hypoglycemic agent 1

Others Others
Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes.
T61855 Antistaphylococcal agent 1

Antistaphylococcal agent 1 是一种抗葡萄球菌的治疗剂。
T32819 L-Lysine, sulfite (2:1)

L-Lysine, sulfite (2:1) is a drug/ therapeutic agent.
TP1874 Alisporivir intermediate-1

Alisporivir intermediate-1 is a crucial intermediate compound utilized in the synthesis process of Alisporivir, a therapeutic agent employed for the treatment of inflammatory and viral ailments.
T81588 Oximbomotide

Oximmotide为用于主动免疫(抗肿瘤)的药剂。
T82499 Efmoroctocog alfa

Efmoroctocog alfa,一种重组人凝血因子 VIII-Fc 融合蛋白(rFVIIIFc),主要应用于血友病 A 研究。
T30169 ASP-8497

UNII-GC7THT248G,ASP8497,ASP 8497

ASP8497 is a potent, long-acting DPP-IV inhibitor that improves glucose tolerance by elevating GLP-1 levels in a glucose-dependent insulin-stimulating manner. The compound is used as a therapeutic agent for impaired glucose tolerance and type 2 diabetes.
T61252 Antitubercular agent-16

Antitubercular agent-16 (Compound 5q) is a potent antitubercular agent exhibiting high efficacy against various strains of M. tuberculosis, including H37Rv, CF16, CF61, CF76, CF152, and CF161, with MIC 90 values ranging from 0.40 to 23.51 μg/mL. Notably, Antitubercular agent-16 demonstrates minimal cytotoxicity towards macrophages and pulmonary fibroblasts, further highlighting its potential as a therapeutic agent [1].
T21330 JNJ-28312141

JNJ 28312141,JNJ28312141

JNJ-28312141 is an orally active CSF1R inhibitor and a FLT3 inhibitor. JNJ-28312141 is a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth a
T39040 HIF-PHD-IN-1

HIF-PHD-IN-1 is a pharmacological compound that acts as an orally active inhibitor of the hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), displaying an IC50 of 54 nM for hHIF-PHD2. Its potential as a therapeutic agent for renal anemia is highly promising.
T61284 Antibacterial agent 94

Antibacterial agent 94 (compound 5b) is a highly effective antibacterial agent that demonstrates strong activity against various bacterial strains. Notably, Antibacterial Agent 94 is capable of eradicating MRSA persisters, highlighting its potential as a therapeutic solution. Its mechanism of action involves interference with the bacterial membrane and disruption of the phosphatidylglycerol (PG) synthesis pathway [1].
T70704 RB-005

RB-005 is a potent sphingosine kinase isoform 1 (SK1) inhibitor, which may serve as therapeutic agent for proliferative diseases, including hypertension. RB-005, (IC(50) = 3.6 μM), which also induced proteasomal degradation of SK1 in human pulmonary arterial smooth muscle cells.
T39274 Lumasiran sodium

Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, targets glycolate oxidase to reduce hepatic oxalate production, thereby reducing urinary oxalate excretion. This compound shows promise in addressing the underlying cause of progressive kidney failure in individuals with primary hyperoxaluria type 1 (PH1).
T62617 QW24

QW24 利用下调 BMI-1 发挥强大的抗肿瘤作用,并作为一种有效的治疗剂用于临床结直肠癌治疗。
T82645 Cyclic PSAP peptide

Cyclic PSAP peptide(DWLPK)是一种环五肽,具有活性分子特性,在体内能够抑制肿瘤转移扩散和发展。
T81643 NR-NO2

NR-NO2是具备靶向释放功能及基于成像指导潜力的抗肿瘤研究药物,同时表现出抗菌活性。
T79288 Antitubercular agent-38

Antitubercula agent-38,一种具有效抗结核活性的口服苯并噻嗪酮(BTZ)衍生物,其特点为低心脏毒性和低细胞毒性。
T61205 Nrf2/HO-1 activator 1

Nrf2/HO-1 activator 1 (Compound 24) 作为一种有效的Nrf2/HO-1激活剂及神经保护剂,展现了神经保护和抗氧化活性,适用于帕金森病 (PD) 研究。
T77074 Lulizumab pegol

Lulizumab pegol (BMS-931699) 为一种抗CD28抗体拮抗剂,能有效抑制T细胞增殖。其主要应用于肾移植和自身免疫性疾病的研究。
T78581 Selenocystine

Others Others
Selenocystine为一种广谱抗癌剂,能诱导HepG2细胞发生DNA损伤,尤其是 DNA 双链断裂(DSBs)。Selenocystine在靶向DNA修复领域,作为癌症治疗的潜在治疗或辅助剂,展现出显著的应用前景。
T36761 KRAS inhibitor-10

KRAS inhibitor-10 (WO2021005165 A1, compound 11) is a potent and selective inhibitor of RAS proteins, with a specific focus on KRAS proteins. This orally active anti-cancer agent demonstrates strong efficacy in cancer research, specifically in pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer. KRAS inhibitor-10 is classified as a tetrahydroisoquinoline compound. Its inhibitory properties provide valuable insights and potential therapeutic applications in the field of ...
T74364 SDOX

Topoisomerase DNA Damage/DNA Repair
SDOX为Doxorubicin的前体药物,通过脂质体递送至肿瘤细胞内,在GSH过量释放条件下,触发DOX释放。该机制在不损害抗癌效果的同时,极大地降低了对正常组织的毒副作用。
T76785 Brontictuzumab

Brontictuzumab (OMP 52M51) 是一种针对 Notch1 信号抑制作用的单克隆抗体 (MAb),其通过选择性结合 Notch1 负调控区域而发挥作用。该化合物有效抑制肿瘤细胞增殖,并被应用于白血病和淋巴瘤的研究中。
T61814 JAK3-IN-9

JAK3-IN-9 is a potent and orally active inhibitor of the Janus kinase 3 (JAK3) enzyme, displaying an impressive IC50 value of 1.7 nM. It exhibits high selectivity towards the JAK3 signaling pathway, making it a valuable tool for studying autoimmune diseases. Additionally, JAK3-IN-9 possesses desirable characteristics such as low toxicity and excellent oral bioavailability. It also demonstrates promising anti-arthritis activity, thus enhancing its potential as a therapeutic agent [1].
T74405 PEG2000-C-DMG

PEG2000-C-DMG,一种 PEG 化修饰的脂质,可用于制备 Onpattro。Onpattro 是一种肝脏导向的研究性 RNAi 有效试剂,通过靶向甲状腺素运载蛋白 mRNA 的3′非翻译区,利用这一过程减少突变型和野生型甲状腺素运载蛋白的产生。
T82798 C3bot(154-182) TFA

C3bot(154-182) TFA 是C3 肽类化合物,能够通过促进脊髓损伤后下行纤维束的再生,增强其修复效能。此外,C3bot(154-182) TFA 或许能够促进中枢神经系统损伤后的轴突保护与修复,并有助于功能性恢复。
T70256 L-163491

L-163491 is a drug which acts as a partial agonist of angiotensin II receptor type 1, and with lower affinity as an agonist of angiotensin II receptor type 2, mimicking the action of angiotensin II. Its practical applications to date have been limited to scientific research into the function of the angiotensin receptor system, but it has been suggested as a potential therapeutic agent for the treatment of inflammation of the lungs associated with certain viral diseases such as COVID-19.
T79699 anti-TNBC agent-2

Apoptosis Apoptosis
Anti-TNBC agent-2(3j)是一款针对三阴性乳腺癌(TNBC)的嘌呤衍生化合物。它能够引导MDA-MB-231细胞走向凋亡(apoptosis),阻碍其迁移和血管生成能力,并在TNBC异种移植模型中,抑制肿瘤生长与转移,同时下调Ki67和CD31蛋白的表达水平。Anti-TNBC agent-2主要用于三阴性乳腺癌的科研领域。
T5499 gardiquimod TFA salt

Gardiquimod diTFA,咪唑啉类似物TLR7/8激动剂,可特异性抑制巨噬细胞和活化外周血单个核细胞(PBMCs)的HIV-1感染。在浓度低于10 μM时,该化合物特异性激活TLR7。
T79702 Nrf2 activator-9

Nrf2 activator-9 (compound D-36) 是抑制oxLDL和HG诱导的HUVEC细胞凋亡的Nrf2激活剂,有助于预防动脉粥样硬化。该化合物可防止VEC损伤,展现出对心血管疾病的潜在治疗效果。
T74672 Sirtuin modulator 5

Sirtuinmodulator 5 是一种sirtuin 调节剂。Sirtuinmodulator 5 可以激活SIRTl,DC50值 <50 μM。Sirtuinmodulator 5 可用于增加细胞的寿命并用于研究多种疾病,包括例如与衰老或压力、糖尿病、肥胖症、神经退行性疾病、心血管疾病、凝血障碍、 炎症、癌症和/或潮红以及将受益于线粒体活性增加的疾病或病症。
T74633 MS9427

MS9427 是一种有效的PROTACEGFR 降解剂,对野生型EGFR 和突变型EGFRL858R 的Kd 分别为 7.1 nM 和 4.3 nM。MS9427 通过泛素/蛋白酶体系统 (UPS) 和自噬/溶酶体途径选择性地降解突变体,但不降解WTEGFR。MS9427 对 NSCLC 细胞增殖有较强的抑制作用。MS9427 可用于抗癌研究。
T37388 Afizagabar

Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1]. Afizagabar (S44819) is a competitive α5-GABAAR antagonist (Kb=221 nM). Afizagabar selectively inhibits extrasynaptic α5-GABAARs of mouse CA1 pyramidal neurons[1]. Afizagabar (1 and 3 mg/kg; i.p.) significantly diminishes t...
T38145 Eltoprazine

Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.IC50 value:Target: 5-HT1A/1B agonist; 5-HT2C antagonistin vitro: The binding of [3H]eltoprazine to whole tissue sections was saturable and revealed an apparent dissociation constant (Kd) of 11 nM. Specific [3H]eltoprazine binding was completely displaced by 5-HT; conversely, unlabelled eltoprazine reduced [3H]5-HT binding to the levels of no...
T83680 Azurin (50-77) (P. aeruginosa) TFA

Azurin p28,p28

Azurin (50-77)是一种含铜细菌蛋白azurin的肽段,存在于P. aeruginosa中,具有细胞周期停滞、抑制癌细胞增殖和调节血管生成活性。作为VEGFR2的抑制剂(IC20约为10.7 µM),Azurin (50-77)(20 µM)能在MCF-7乳腺癌细胞中诱导G2/M期的细胞周期停滞。在50 µM的浓度下,减少MCF-7和ZR-75-1乳腺癌细胞的增殖。Azurin (50-77)以25 µM的浓度减少VEGF-A诱导的毛细管管腔形成(IC50 = 12 µM),降低人脐静脉内皮细胞(HUVECs)中与细胞膜相关的F-actin、焦点粘附激酶(FAK)和paxillin的水平,并增加胞外的血小板内皮细胞粘附分子-1(PECAM-1)的水平。在体内,Azurin (50-77)(每日10 mg/kg)在MCF-7小鼠异种移植模型中减少肿瘤体积。
T36807 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...
T35683 2-deoxy-D-Glucose-13C6

2-deoxy-D-Glucose-13C6

2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...

化合物

Therapeutic agent-1
Cat.No: T80994
Synonym:
Target:
1-phenyl-3,4-dihydroisochinoline
Cat.No: T9340
Synonym: 3,4-Dihydro-1-phenylisoquinoline,1-苯基-3,4-二氢异喹啉
Target: Others
NS13001
Cat.No: T16345
Synonym: N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine
Target: Potassium Channel
PDE4-IN-20
Cat.No: T50023
Synonym:
Target: Others
Hypoglycemic agent 1
Cat.No: T19367
Synonym:
Target: Others
Antistaphylococcal agent 1
Cat.No: T61855
Synonym:
Target:
L-Lysine, sulfite (2:1)
Cat.No: T32819
Synonym:
Target:
Alisporivir intermediate-1
Cat.No: TP1874
Synonym:
Target:
Oximbomotide
Cat.No: T81588
Synonym:
Target:
Efmoroctocog alfa
Cat.No: T82499
Synonym:
Target:
ASP-8497
Cat.No: T30169
Synonym: UNII-GC7THT248G,ASP8497,ASP 8497
Target:
Antitubercular agent-16
Cat.No: T61252
Synonym:
Target:
JNJ-28312141
Cat.No: T21330
Synonym: JNJ 28312141,JNJ28312141
Target:
HIF-PHD-IN-1
Cat.No: T39040
Synonym:
Target:
Antibacterial agent 94
Cat.No: T61284
Synonym:
Target:
RB-005
Cat.No: T70704
Synonym:
Target:
Lumasiran sodium
Cat.No: T39274
Synonym:
Target:
QW24
Cat.No: T62617
Synonym:
Target:
Cyclic PSAP peptide
Cat.No: T82645
Synonym:
Target:
NR-NO2
Cat.No: T81643
Synonym:
Target:
Antitubercular agent-38
Cat.No: T79288
Synonym:
Target:
Nrf2/HO-1 activator 1
Cat.No: T61205
Synonym:
Target:
Lulizumab pegol
Cat.No: T77074
Synonym:
Target:
Selenocystine
Cat.No: T78581
Synonym:
Target: Others
KRAS inhibitor-10
Cat.No: T36761
Synonym:
Target:
SDOX
Cat.No: T74364
Synonym:
Target: Topoisomerase
Brontictuzumab
Cat.No: T76785
Synonym:
Target:
JAK3-IN-9
Cat.No: T61814
Synonym:
Target:
PEG2000-C-DMG
Cat.No: T74405
Synonym:
Target:
C3bot(154-182) TFA
Cat.No: T82798
Synonym:
Target:
L-163491
Cat.No: T70256
Synonym:
Target:
anti-TNBC agent-2
Cat.No: T79699
Synonym:
Target: Apoptosis
gardiquimod TFA salt
Cat.No: T5499
Synonym:
Target:
Nrf2 activator-9
Cat.No: T79702
Synonym:
Target:
Sirtuin modulator 5
Cat.No: T74672
Synonym:
Target:
MS9427
Cat.No: T74633
Synonym:
Target:
Afizagabar
Cat.No: T37388
Synonym:
Target:
Eltoprazine
Cat.No: T38145
Synonym:
Target:
Azurin (50-77) (P. aeruginosa) TFA
Cat.No: T83680
Synonym: Azurin p28,p28
Target:
Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
Cat.No: T36807
Synonym:
Target:
2-deoxy-D-Glucose-13C6
Cat.No: T35683
Synonym: 2-deoxy-D-Glucose-13C6
Target:
Cat. No. Product Name Target Signaling Pathways
T5S1895 Norisoboldine

Laurelliptine,去甲异波尔定,(+)-Laurelliptine

MAPK; Adenosine Receptor GPCR/G Protein; MAPK; Neuroscience
Norisoboldine ((+)-Laurelliptine) 是一种可口服的芳基烃受体激动剂,是乌药中主要的异喹啉类生物碱,可用于类风湿性关节炎和溃疡性结肠炎的研究。
T6S0232 Eriodictyol

圣草酚,Huazhongilexone

Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物,具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 18 nM。它可诱导Nrf2信号通路。
T5S0754 Isoquercetin

3-Glucosylquercetin,Hirsutrin,Isoquercitrin,异槲皮苷,Quercetin 3-o-glucopyranoside,槲皮素-3-葡萄糖苷

NF-κB; Wnt/beta-catenin; NO Synthase Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; Stem Cells
Isoquercetin (3-Glucosylquercetin) 是天然存在的多酚,具有抗氧化,抗增殖和抗炎特性。它通过调节核因子-κB 转录调节系统调节一氧化氮合酶 2 的表达。它通过 Nrf2/ARE 抗氧化剂信号传导途径减轻乙醇诱导的肝毒性,氧化应激和炎症反应。它具有高生物利用度和低毒性,是预防糖尿病妊娠出生缺陷的有希望的候选药物。
T4S0797 Berberine

小檗碱,Berberin,Umbellatine,黄连素

Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Berberine (Umbellatine) 属于生物碱类天然产物,可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。
T6S0721 Orientin

荭草苷,Lutexin,Luteolin-8-glucoside

Others Others
Orientin (Luteolin-8-glucoside) 是天然存在的生物活性类黄酮,是一种有前景的神经保护剂,具有多种生物特性,如抗炎、抗肿瘤、抗氧化、保护心脏等。它有用于神经性疼痛研究潜力。
T3673 Mollugin

大叶茜草素,Rubimaillin

HER; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Mollugin (Rubimaillin) 是Rubia cordifolia L.中主要的生物活性成分。它能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。它通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。
T5S0055 Chelidonine

Helidonine,Khelidonin,白屈菜碱,Stylophorin

Apoptosis; Others; Influenza Virus Apoptosis; Microbiology/Virology; Others
Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱,有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞,诱导 caspase 依赖和非依赖性的细胞凋亡。
T6S1487 Ginsenoside Rg5

人参皂苷Rg5,人参皂甙 Rg5

NF-κB; COX; IGF-1R Immunology/Inflammation; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
Ginsenoside Rg5 是红参的主要成分,可阻断IGF-1与其受体的结合,IC50约为90 nM。它还通过抑制NF-κB p65的 DNA 结合活性来抑制COX-2的 mRNA 表达。它可促进血管生成和改善高血压,具有抗炎和治疗阿尔茨海默病的潜力。
T4S2126 Ginkgetin

银杏双黄酮,银杏素

Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
Ginkgetin 是从银杏叶中分离得到的一种双黄酮,具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂,IC50值为 5.92 μM。
T6S1315 Oroxylin A

千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮,具有较强的抗癌作用。
TN3003 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol

ERK; p38 MAPK MAPK
(E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypopigmentation-associated diseases.
TN3882 Dodoviscin A

cAMP; Tyrosinase; transporter GPCR/G Protein; Metabolism; Proteases/Proteasome
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote adipocyte differentiation as charact
T78492 D-Mannuronic acid sodium

D-Mannuronic acid sodium,一种可从Macrocystis pyrifera中分离得到的化合物,显示出在自身免疫性脑脊髓炎(EAE)、佐剂性关节炎(AIA)、肾病综合征以及急性肾小球肾炎的研究中具有潜在应用价值。
T14317 ar-Turmerone

(+)-ar-Turmerone

Others Others
ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation.

天然产物

Norisoboldine
Cat.No: T5S1895
Synonym: Laurelliptine,去甲异波尔定,(+)-Laurelliptine
Target: MAPK, Adenosine Receptor
Eriodictyol
Cat.No: T6S0232
Synonym: 圣草酚,Huazhongilexone
Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite
Isoquercetin
Cat.No: T5S0754
Synonym: 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,异槲皮苷,Quercetin 3-o-glucopyranoside,槲皮素-3-葡萄糖苷
Target: NF-κB, Wnt/beta-catenin, NO Synthase
Berberine
Cat.No: T4S0797
Synonym: 小檗碱,Berberin,Umbellatine,黄连素
Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy
Orientin
Cat.No: T6S0721
Synonym: 荭草苷,Lutexin,Luteolin-8-glucoside
Target: Others
Mollugin
Cat.No: T3673
Synonym: 大叶茜草素,Rubimaillin
Target: HER, JAK
Chelidonine
Cat.No: T5S0055
Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin
Target: Apoptosis, Others, Influenza Virus
Ginsenoside Rg5
Cat.No: T6S1487
Synonym: 人参皂苷Rg5,人参皂甙 Rg5
Target: NF-κB, COX, IGF-1R
Ginkgetin
Cat.No: T4S2126
Synonym: 银杏双黄酮,银杏素
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Oroxylin A
Cat.No: T6S1315
Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy
4-(3,4-Dimethoxyphenyl)-3-buten-1-ol
Cat.No: TN3003
Synonym:
Target: ERK, p38 MAPK
Dodoviscin A
Cat.No: TN3882
Synonym:
Target: cAMP, Tyrosinase, transporter
D-Mannuronic acid sodium
Cat.No: T78492
Synonym:
Target:
ar-Turmerone
Cat.No: T14317
Synonym: (+)-ar-Turmerone
Target: Others
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