348
40
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5457 |
SN 6
SN6 |
Calcium Channel; Na+/Ca2+ Exchanger | Membrane transporter/Ion channel; Metabolism |
SN 6 (SN6) 是选择性NCX 抑制剂,可抑制 NCX1、NCX2 和 NCX3 对45Ca2+的吸收,IC50值分别为 2.9、16 和 8.6 μM。 | |||
T12941 |
SN 2
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
SN 2 是TRPML3离子通道的有效激活剂,EC50为 1.8 μM。它对登革热病毒 2 和寨卡病毒具有有效的抑制作用。 | |||
T9554 |
SN-008
|
STING | Immunology/Inflammation |
SN-008 是 SN-011 的低活性类似物,可作为阴性对照。 | |||
T22463 |
1,2-Dilauroyl-sn-glycerol
1,2-DLG,(S)-1,2-Dilaurin,1,2-二月桂酰-SN-甘油 |
Others | Others |
1,2-Dilauroyl-sn-glycerol ((S)-1,2-Dilaurin) 是饱和二酰甘油的一种,可能在第二信使信号转导中发挥调节作用。 | |||
T35606 |
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium
1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) |
||
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) 可与 DOPC 和 DOPE 一起用于脂质混合物中,作为有效的无毒和非病毒 DNA 载体。 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium 已用于单层囊泡的形成,以研究曲率对膜结构的影响,并用于支持脂质双层的形成,以研究各种支持膜小叶之间脂质重新分布的材料。 | |||
T9204 |
SN-001
|
STING | Immunology/Inflammation |
SN-001 是一种 STING 抑制剂,可抑制 STING 信号通路的激活并预防或治疗 STING 介导的疾病。 | |||
T9137 |
SN-011
[1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901 |
STING | Immunology/Inflammation |
SN-011 (GUN35901) 是选择性 STING 抑制剂,可与环状二核苷酸 (CDN) 竞争 STING 二聚体的结合口袋,从而阻断 CDN 结合和 STING 激活。它用于 STING 驱动的自身免疫和炎症性疾病的研究,抑制 STING 信号传导的 IC50值为 76 nM。 | |||
T22465 |
1,2-Distearoyl-sn-glycerol
|
Others | Others |
1,2-Distearoyl-sn-glycerol 是一种内标物,可用于分离和鉴定 1,2-diacyl-sn-glycerol (DAG) 的分子种类。 | |||
T17731L |
CL2A-SN-38 DCA 1279680-68-0(free base)
|
Others | Others |
CL2A-SN-38 DCA 1279680-68-0(free base) 是一种药物-接头偶联物,由有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成,用于制造抗体药物偶联物 (ADC)。CL2A-SN-38 由有效的 DNA 拓扑异构酶组成I 抑制剂 SN-38 和接头 CL2A 以制造抗体药物偶联物 (ADC)。 CL2A-SN-38 对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 CL2A 是一种不可切割的复杂 PEG8 和含有三唑的 PABC-肽-mc 接头。 CL2A 可通过 pH 敏感性裂解,产生旁观者效应,并通过二硫键在半胱氨酸残基处结合抗体。 | |||
T9788 |
SN32976
|
PI3K | PI3K/Akt/mTOR signaling |
SN32976 是一种泛 PI3K 抑制剂。 SN32976 有效抑制 PI3K 亚型和 mTOR,显示出对 PI3Kα 的优先活性和对 PI3Kδ 的保留。 | |||
T4949 |
1,2-Didecanoyl-sn-glycero-3-phosphocholi
1,2-Didecanoyl Phosphatidylcholine,1,2-Didecanoyl PC,L-A-癸酰磷脂酰胆碱 |
Others | Others |
1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) 是一种合成的、疏水性较低的磷脂,已被发现可用于增强肽类药物和激素(如胰岛素)的吸收。 | |||
T10022 |
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
|
Endogenous Metabolite | Metabolism |
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 是一种人内源性代谢产物。 | |||
TF0112 |
DPPS
12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na |
Others | Others |
DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) 是一种阴离子二酰基磷脂,是磷脂酰丝氨酸(PS)的一种形式,是一种位于细胞膜内小叶的带负电荷的磷脂。DPPS 被用来制作阳离子囊泡和脂质体。 | |||
T35482 |
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine |
||
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-... | |||
T36004 |
1-O-Hexadecyl-sn-glycerol
1-O-Hexadecyl-sn-glycerol,(S)-(+)-Chimyl Alcohol,α-Chimyl Alcohol |
||
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury. [2].Maulik, N., Tosaki, A., Engelman, R.M., et al. Myocardial salvage by chimyl al... | |||
T12942L |
SN50 acetate (213546-53-3 free base)
|
NF-κB | NF-κB |
SN50 acetate (213546-53-3 free base) 是一种可渗透细胞的 NF-κB 易位抑制剂。 | |||
T34665 |
SN-1
SN1 |
||
SN-1 is a zinc chelator which increases steady-state expression level of A3G in the presence of Vif. | |||
T69193 | SN-28049 | ||
SN-28049 SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 has a complex action that may involve poisoning of topo IIalpha, suppression of topo I and inhibition of gene transcription from promoters with SP-1 sites. These actions may contribute to the promising experimental solid tumour anticancer activity of SN 28049. | |||
T0942 |
Quinacrine dihydrochloride
疟疾平,Mepacrine dihydrochloride,阿的平,SN-390,Quinacrine 2HCl |
Apoptosis; Mitophagy; DNA; Phospholipase; Parasite; Autophagy; Histamine Receptor | Apoptosis; Autophagy; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Quinacrine dihydrochloride (Mepacrine dihydrochloride) 是一种具有口服活性的抗疟剂,抑制 NF-κB 并激活 p53 信号转导,诱导肿瘤细胞发生凋亡,具有抗肿瘤和抗寄生虫活性。 | |||
T17731 |
CL2A-SN-38
|
Others | Others |
CL2A-SN-38 是一种药物-接头偶联物,由一种有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成,用于制造抗体药物偶联物。它对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 | |||
T1439 |
Lacidipine
SN-305,拉西地平,GX-1048,GR-43659X |
Apoptosis; Calcium Channel; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB |
Lacidipine (SN-305) 是一种L 型钙离子通道阻断剂。 | |||
T23373 |
SN 003
|
Others | Others |
SN 003 is a CRF1 antagonist. | |||
T39222 |
Mc-VC-PAB-SN38
Mc-VC-PAB-SN38 |
Others | Others |
Mc-VC-PAB-SN38 由可降解 (cleavable) 的 ADC linker (Mc-VC-PAB) 和 SN38 组成,属于抗体偶联活性分子的一部分,常用来合成靶向作用位点的抗体偶联活性分子 (ADC)。 | |||
T6615 |
Ondansetron
GR-C507/75,GR 38032,昂丹司琼,GR 38032F,SN 307,恩丹西酮 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Ondansetron (GR 38032) 是一种血清素 5-HT3 受体拮抗剂,主要用作止吐剂。 | |||
T37122 |
1,2-Dilinoleoyl-sn-glycerol
|
||
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy. | |||
T37502 |
sn-Glycerol 3-phosphate lithium
|
||
sn-Glycerol 3-phosphate lithium is synthesized via the cytosolic glycerol 3-phosphate dehydrogenase pathway. This process involves the conversion of dihydroxyacetone phosphate to sn-Glycerol 3-phosphate using NADH, which is generated during glycolysis. | |||
T1478 |
Ondansetron hydrochloride dihydrate
盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Ondansetron hydrochloride dihydrate (GR 38032) 是5- HT3受体拮抗剂,可治疗化疗后的恶心和呕吐,有抗焦虑和抗精神病作用。 | |||
T19080 |
DOPE
1,2-二油酰-SN-甘油-3-磷酰乙醇胺 |
Others | Others |
DOPE (DOPE) 是一种阳离子脂质体的中性辅助脂质 (helper lipid),能够与阳离子磷脂结合,增强裸 siRNA 的转染效率。 | |||
T10832 |
CL2-SN-38
|
Others | Others |
CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is an inhibitor of DNA topoisomerase I. | |||
T37623 |
1,2-Dierucoyl-sn-glycero-3-PC
|
||
1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP). | |||
T36451 |
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt),biotin-cap-DPPE |
||
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. [1] It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. [2] In addition, 1,2-dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) has been used i... | |||
T67435 |
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
|
||
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67435,CAS号为 200880-42-8。 | |||
T40972 |
1-Oleoyl-2-acetyl-sn-glycerol
|
||
1-Oleoyl-2-acetyl-sn glycerol, a synthetic, cell-permeable diacylglycerol analog, activates calcium-dependent protein kinase C (PKC) and induces superoxide production. | |||
T29298 | 1-Dodecanoyl-sn-glycerophosphoethanolamine | ||
1-Dodecanoyl-sn-glycerophosphoethanolamine is a bioactive cehmical. | |||
T40757 |
1-Stearoyl-2-arachidonoyl-sn-glycerol
|
||
1-Stearoyl-2-arachidonoyl-sn-glycerol, a diacylglycerol (DAG) encompassing polyunsaturated fatty acids, possesses the ability to activate PKC. Moreover, this compound has the potential to enhance nonselective cation channel (NSCC) activity. | |||
T38356 |
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
|
||
1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation... | |||
T37043 |
1,2-Dihexadecyl-sn-glycero-3-PC
|
||
1,2-Dihexadecyl-sn-glycero-3-PC 可用于生命科学领域的相关研究。其产品编号为 T37043,CAS号为 36314-47-3。 | |||
T6616 |
Ondansetron hydrochloride
SN 307,盐酸昂丹司琼,帕罗西汀杂质A,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Ondansetron hydrochloride (Zofran) 是5-HT3受体的拮抗剂,可用作化疗后止吐剂。 | |||
T26196 |
SN34037
SN-34037,SN 34037 |
||
SN34037 is a specific Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) inhibitor. | |||
T36453 |
1-Myristoyl-2-hydroxy-sn-glycero-3-PE
|
||
1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. It induces transient increases in intracellular calcium in PC12 cells. Serum levels of 1-myristoyl-2-hydroxy-sn-glycero-3-PE are elevated in patients with malignant breast cancer compared to healthy controls. | |||
T38217 |
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE
|
||
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid and adrenic acid at thesn-1 andsn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.1 1.Hancock, S.E., Friedrich, M.G., Mitchell, T.W., et al.Decreases in phospholipids containing adrenic and arachidonic acids occur in the human hippocampus over the adult lifespanLipids50(9)861-872(2015) | |||
T35489 |
1-O-Octadecyl-2-O-methyl-sn-glycerol
|
||
1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity. | |||
T18538 |
MAC glucuronide phenol-linked SN-38
|
Others | Others |
MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1]. | |||
T19105 |
2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol
|
Others | Others |
2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride. | |||
T10005 |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate
|
Others | Others |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate, a phosphatidic acid, is a human endogenous metabolite. | |||
T34671 |
SNIPER(CRABP)-11
SN 11,SN11,SN-11 |
||
SNIPER(CRABP)-11 is a potent protein degrader. SNIPER(CRABP)-11 displayed degradation activity toward the mitochondrial CRABP-II protein. | |||
T32418 |
KP-1212
KP1212,SN-1212,SN 1212,SN1212,KP 1212 |
||
KP-1212( SN-1212) is a nucleoside designed for the treatment of HIV by viral mutagenesis. | |||
T67812 |
Tenifatecan
SN2310 |
||
Tenifatecan (SN2310) 是一种高度亲脂性的7-乙基-10-羟基喜树碱(SN)制剂,具有潜在的抗肿瘤活性。 | |||
T38460 |
SN52
|
||
SN52 is a powerful, competitive, and cell-permeable inhibitor of NF-κB2. It is a variant of the SN50 peptide. SN52 effectively prevents the nuclear translocation of p52-RelB heterodimers, exhibiting a robust radiosensitization effect on prostate cancer cells. This compound holds significant potential for cancer research purposes. | |||
T37485 |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
|
||
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1703 |
SN-38
7-乙基-10-羟基喜树碱,NK012,伊立替康杂质B,SN 38 |
DNA/RNA Synthesis; Topoisomerase; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
SN-38 (NK012) 是 DNA 拓扑异构酶 I (Topo I) 抑制剂 Irinotecan 的活性代谢产物,可以抑制 DNA 和 RNA 合成 (IC50=0.077/1.3 μM)。SN-38 具有抗肿瘤活性,可以诱导细胞自噬。 | |||
T5249 |
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
1,2-DSPE,1,2-二硬酯酰-SN-甘油-3-磷酰乙醇胺,1,2-Distearoyl-sn-glycero-3-phosphoethan |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) 是一种磷脂酸乙醇胺 (PE) ,能够用于合成脂质体。 | |||
T8712 |
1-Palmitoyl-sn-glycero-3-phosphocholine
1-十六酰-SN-丙三醇-磷酸胆碱,1-Hexadecanoyl-sn-glycero-3-phosphocholine |
Others | Others |
1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) 是一种用于荧光探针设计的磷酸胆碱。 | |||
T5238 |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
1,2-Dipalmitoyl-sn-glycero-3-PE,L-磷脂酰乙醇胺,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) 是内源性代谢产物的一种。 | |||
T8713 |
1-Oleoyl-sn-glycero-3-phosphocholine
|
Others | Others |
1-Oleoyl-sn-glycero-3-phosphocholine 是分析溶血卵磷脂的参考。 | |||
T9525 |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine
DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL,二肉豆蔻酰磷脂酰胆碱(DMPC) |
Others | Others |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) 是一种用于脂质体和脂质双层的合成磷脂。它可用于脂质单层和双层的研究。 | |||
T8714 |
1-Stearoyl-sn-glycero-3-phosphocholine
1-硬脂酰-SN-甘油-3-磷酰胆碱,1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY |
Others | Others |
1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) 是一种用于脂质代谢研究的化学物质。 | |||
T9510 |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine
DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC,二硬脂酰磷脂酰胆碱 |
Others | Others |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) 是一种脂质纳米颗粒(LNP) 系统中的脂质成分,可用于合成脂质体。 | |||
T19085 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。 | |||
T4950 |
1,2-Dipalmitoyl-sn-glycerol
1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin |
Endogenous Metabolite; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism |
1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) 是内源性代谢产物的一种。 | |||
T22464 |
1,2-Dimyristoyl-sn-glycerol
1,2-DMG,1,2-二肉豆蔻酸甘油酯 |
Others; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Others |
1,2-Dimyristoyl-sn-glycerol (1,2-DMG) 是饱和二酰甘油的一种,可作为激活 PKC 的弱活性第二信使。 | |||
T8011 |
1,2-dioleoyl-sn-glycero-3-phosphocholine
二油酰磷脂酰胆碱,DOPC |
Others | Others |
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 是磷脂的一种,在胶束,脂质体和其他类型的人工膜的生成中通常单独使用或与其他组分一起使用。 | |||
T4439 |
sn-Glycero-3-phosphocholine
Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC |
Endogenous Metabolite; AChE | Metabolism; Neuroscience |
sn-Glycero-3-phosphocholine (Choline glycerophosphate) 是脑磷脂生物合成的前体,能够提高胆碱在神经组织中的生物利用度。它对认知功能有显著影响,同时具有良好的耐受性和安全性,因此能够用于阿尔茨海默病和痴呆症的研究。 | |||
T10005L |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
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Endogenous Metabolite | Metabolism |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 是一种人内源性代谢物,是一种磷酸酯。 | |||
T19343 |
sn-Glycerol 3-phosphate
Glycerol 3-phosphate,SN-甘油3-磷酸 锂盐,sn-Glycerol 3-phosphate lithium salt |
Endogenous Metabolite | Metabolism |
sn-Glycerol 3-phosphate 是一种人内源性化合物,由NADH 还原磷酸二羟基丙酮而产生。 | |||
TN7245 |
DMPS-Na
1,2-Dimyristoyl-sn-glycero-3-phosphoserine sodium salt |
Others | Others |
DMPS-Na 是一种带有毒性的解砷灵,可用于研究细胞膜。 | |||
T5243 |
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate
DMPE,1,2-十四酰基磷脂酰乙醇胺,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE |
Others; Endogenous Metabolite | Metabolism; Others |
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (DMPE) 是内源性代谢产物的一种。 | |||
T7773 |
DPPC
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL,二棕榈酸磷脂酰胆碱,129Y83 |
Endogenous Metabolite | Metabolism |
DPPC (129Y83) 是一种磷酸甘油酯,能够用于制备脂质体单层。DPPC-脂质体能够用作小鼠中诱导针对 GSL 抗原的免疫应答的递送载体。 | |||
T19087 |
1-Arachidoyl-sn-glycero-3-phosphocholine
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Others | Others |
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP). | |||
T37280 |
PE(18:1(9Z)/0:0)
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Endogenous Metabolite | Metabolism |
PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂,是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生,但不增加 IFN-γ 的产生。 在小鼠血清中,PE(18:1(9Z)/0:0)(1 μg/动物)诱导 T 辅助细胞 2 反应。 在寒冷暴露三天后,小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。 | |||
T64571 | 1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt | ||
1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt 是一种天然产物,可用于生命科学领域的相关研究,其产品编号为 T64571。 | |||
T74236 |
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC
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1-Oleoyl-2-palmitoyl-sn-glycero-3-PC,由油酸衍生,用于脂质体合成。 | |||
T36791 |
Lysophosphatidylcholine 18:2
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1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid at thesn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.2 1.Okudaira, M., Inoue, A., Shuto, A., et al.Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MSJ. Lipid Res.55(10)2178-2192(2014) 2.Gall, ... | |||
T6354 |
(+)-Usnic acid
D-Usnic Acid,松萝酸,(+)-Usniacin,(+)-地衣酸 |
Antiviral; Antibacterial; mTOR | Immunology/Inflammation; Microbiology/Virology; PI3K/Akt/mTOR signaling |
(+)-Usnic acid (D-Usnic Acid) 是地衣中的二苯并呋喃衍生物,可结合 mTOR 的 ATP 结合口袋,抑制 mTORC1/2的活性。它诱导自噬,有抗菌和抗肿瘤活性。 | |||
T8198 |
Visnagin
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Others | Others |
Visnagin 是一种抗氧化剂呋喃香豆素衍生物。它具有预防Cerulein 诱导的急性胰腺炎的潜力。它在血管平滑肌中具有良好的血管扩张作用。它具有抗炎作用,可用于缓解疼痛的研究。 | |||
T2731 |
Usnic Acid
Usniacin,松萝酸,地衣酸 |
Antibacterial; Autophagy | Autophagy; Microbiology/Virology |
Usnic Acid (Usniacin) 是地衣次生代谢产物,具有独特的二苯并呋喃骨架。它是一种抗菌剂、抗肿瘤剂和酶抑制剂。 | |||
T5694 |
Usnic Acid sodium
2,6-二乙酰基-7,9-二羟基-8,9b-二甲基二苯并呋喃-1,3(2H,9bH)-二酮单钠盐 |
Others | Others |
Usnic Acid sodium 是一种天然产品。 | |||
T81618 |
Officinalisnin-II
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Officinalisnin-II为Asparagus filicinus根中检出的自然皂苷。 | |||
TN3585 |
Canusesnol A
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Others | Others |
Canusesnol A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3585,CAS号为 816456-90-3。 | |||
TN5565 |
Jasnervoside G
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Jasnervoside G 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5565,CAS号为 1622337-40-9。 | |||
TN5736 |
Jasnervoside C
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Jasnervoside C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5736,CAS号为 1622337-36-3。 | |||
T82429 |
Euphoheliosnoid A
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Euphoheliosnoid A (Compound 24) 为二萜类化合物,以 2.5 μM 浓度显著提升 NK 细胞针对 H1299-luci 及 A549-luci 细胞的杀伤效率。 | |||
T83569 |
(25R)-Officinalisnin-II
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(25R)-Officinalisnin-II(化合物 5)作为一种呋甾烷醇糖苷,主要分布于Asparagus curillus果实中。 | |||
T5S0483 |
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside
(-)-丁香树脂酚-4-O-beta-D-呋喃芹糖基-(1→2)-beta-D-吡喃葡萄糖苷,(-)-Syringaresnol-4-O-beta-D-apiofuranos |
Others | Others |
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) 是从Albizzia myriophylla 的树皮部分分离得到。 | |||
T0486L |
Irinotecan Hydrochloride
盐酸伊立替康,伊立替康盐酸盐,Camptothecin 11 hydrochloride,CPT-11 hydrochloride |
Topoisomerase; Autophagy | Autophagy; DNA Damage/DNA Repair |
Irinotecan Hydrochloride (CPT-11 hydrochloride) 是喜树碱半合成衍生物的盐酸盐,是一种拓扑异构酶 I 抑制剂,可研究结肠癌和直肠癌。 | |||
T38141 |
Glycerophospholipids, cephalins
Phosphatidylethanolamines (egg) |
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Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。 | |||
T6S1559 |
Aurantio-obtusin
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Others | Others |
Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物,具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应,具有研究过敏相关疾病的潜力。在大鼠中,它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉,是潜在的新型血管扩张剂。 | |||
TQ0260 |
Cerulenin
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Antibiotic; Antifungal; Fatty Acid Synthase | Metabolism; Microbiology/Virology |
Cerulenin 是广泛使用的天然脂肪酸合成酶抑制剂。它是由真菌Cephalosporium caeruleus 产生的。它抑制拓扑异构酶I 催化活性并增强 SN-38 诱导的细胞凋亡。它具有抗真菌和抗肿瘤活性。 | |||
T37884 |
1,3-Linolein-2-Olein
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1,3-Dilinoleoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains linoleic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. It has been found in grape seed, pumpkin seed, soybean, sunflower, and wheat germ oils, with the highest content in grape seed oil. | |||
T35577 |
Phosphatidylserines (bovine)
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Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi... |