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45

抑制剂 & 化合物

18

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T74658	HBPC–GSH
	HBPC-GSH，一种谷胱甘肽衍生物，作为糖醛酸酶(Glo)抑制剂，展示出对cGloII的IC50为0.6 μM，对cGloIII的IC50为1.6 μM，可用于抗疟疾研究。
T80056	Glutathione Peroxidase GSH-Px,EC 1.11.1.9	Glutathione Peroxidase	Metabolism
	Glutathione Peroxidase (GSH-Px; EC 1.11.1.9)，是一种关键的抗氧化酶，能催化GSH与过氧化氢或脂质过氧化物反应，生成GSSG和H2O，从而减缓氧化应激。此酶在生化研究中具有重要应用。
T7831	Nitecapone	Others; Transferase	Metabolism; Others
	Nitecapone 是一个具有口服活性的、短效的儿茶酚-O-甲基转移酶(COMT)的抑制剂。它具有胃肠道保护和抗氧化活性，能够清除活性氧和一氧化氮，防止脂质过氧化。
T38155	N-Acetyl-D-cysteine	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	N-Acetyl-D-cysteine 具有抗氧化活性，机制是通过与巯基反应清除ROS。N-Acetyl-D-cysteine 不能进入谷胱甘肽代谢途径。
T1052	Proglumide 二丙谷酰胺	cholecystokinin	GPCR/G Protein
	Proglumide (Binoside) 是一种非肽的、口服具有活性的胆囊收缩素(CCK)-A/B 受体拮抗剂。它能够选择性阻断 CCK 在中枢神经系统中的作用。它能够抑制胃分泌，具有保护胃十二指肠粘膜的能力，并表现出抗癫痫和抗氧化活性。
T21480	Diethylmaleate Maleic acid, diethyl ester,DIETHYL MALEATE,马来酸二乙酯	NF-κB	NF-κB
	Diethylmaleate (Maleic acid, diethyl ester) 是马来酸二乙酯和一种抑制 NF-kB 的谷胱甘肽消耗化合物。
T14042	4-P-PDOT 4-phenyl-2- propionamidotetralin	Melatonin Receptor; MT Receptor	GPCR/G Protein; Neuroscience
	4-P-PDOT (4-phenyl-2- propionamidotetralin) 是一种选择性和亲和性的褪黑激素受体拮抗剂，可显著抵消褪黑激素介导的抗氧化作用。它对MT2的选择性是 MT1 的 300 倍以上。
T70601	MDK03855
	MDK03855, also known as A2AR antagonist 19, is an adenosine A2A receptor (A2AR) antagonist. MDK03855 has CAS#1454903-85-5. The last five digit of CAS# was used for name.
T5371	L-BUTHIONINE-(S,R)-SULFOXIMINE L-Butionine sulfoximine,丁硫氨酸-亚砜亚胺	Others; Ferroptosis	Apoptosis; Others
	L-Buthionine-(S,R)-sulfoximine 是一种细胞渗透性和不可逆的 γ-谷氨酰半胱氨酸合成酶抑制剂，通过消耗 GSH 诱导细胞中的氧化应激，可降低细胞内谷胱甘肽的水平，其对黑色素瘤、乳腺卵巢癌标本的 IC50值分别为1.9 μM、8.6 μM 和29 μM。
T71439	Opc 4392
	Opc 4392 is an agonist of presynaptic dopamine D(2) receptor.
T28804	Slingshot inhibitor D3 JHN76359	Others	Others
	Slingshot inhibitor D3 (JHN76359) 是具有选择性、竞争性、可逆性的Slingshot 抑制剂。它对Slingshot 1和Slingshot 2具有相似的抑制活性。它对Slingshot 1 的IC50为 3 μM；对Slingshot 2 的Ki 为 3.9 μM。
T38968	GSHtracer
	GSHtracer is a ratiometric probe designed for the quantification of glutathione (GSH) concentrations. This probe demonstrates a measurable shift in its excitation-emission profile, specifically from 520/580 nm to 430/510 nm, upon binding with GSH.
T3646	RSL3 RSL3 1S,1S,3R-RSL3	Ferroptosis; GPX; Glutathione Peroxidase	Apoptosis; Metabolism; oxidation-reduction
	RSL3 (RSL3 1S) 是一种 GPX4 的抑制剂，抑制阻断 GSH 合成的 system xc- (IC50=100 nM)。RSL3 是一种不依赖 VDAC 的铁死亡激活剂，对携带致癌 RAS 的肿瘤细胞具有选择性。
T77650	Topoisomerase II inhibitor 14	Apoptosis; Antioxidant; Topoisomerase; NO Synthase	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; oxidation-reduction
	Topoisomerase II inhibitor 14 是一种有效的拓扑异构酶 II 抑制剂，具有抗癌活性和抗氧化活性。Topoisomerase II inhibitor 14 诱导细胞凋亡，并将细胞周期阻滞在 S 期。Topoisomerase II inhibitor 14 可降低 GSH、MDA 和 NO 的量。
T19028	Monochlorobimane mBBr,Chlorobimane
	Monochlorobimane (mBBr) 是一种荧光染料 ,λex 值为380 nm，λem 值为470 nm。Monochlorobimane 可用于测定细胞中谷胱甘肽 (GSH)。
T5365	Oxothiazolidinecarboxylic acid Oxothiazolidine carboxylate,Procysteine,丙半胱氨酸	Antioxidant	oxidation-reduction
	Oxothiazolidinecarboxylic acid (Procysteine) 是半胱氨酸的前药，是一种抗氧化剂，它是惰性的，在细胞内代谢成半胱氨酸，从而刺激谷胱甘肽的合成。
T35689	MTP 131 acetate	Others	Others
	MTP 131 acetate 是一种小的线粒体靶向四肽。
T34605	Selenodiglutathione Seleno-di-glutathione,Bis(glutathione) selenide
	Selenodiglutathione is a primary Se metabolite conjugated with two glutathione (GSH) moieties.
T78616	Glutathione ethyl ester	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Glutathione ethyl ester 为细胞渗透性的GSH供体，能为卵母细胞提供高效率的谷胱甘肽供给。该化合物通过提升抗氧化防御，对胚胎体外生产具有促进效应。
T82498	Eftansomatropin alfa
	Eftansomatropin alfa是一种融合蛋白，由GH1与IGHG4 Fc结合而成，旨在靶向生长激素受体(GSH)。
T36173	L-Glutathione, oxidized (sodium salt)
	Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The rat...
T74064	ent-Kaurene
	ent-Kaurene 是一种二萜类化合物，通过靶向抗氧化蛋白和消耗 GSH 诱导 ROS 积累，从而触发细胞凋亡和铁死亡。
T69073	COTC
	COTC is a bacterial metabolite that has anticancer activity and inhibits glyoxalase in the presence of glutathione (GSH) and the proliferation of HeLa cells, as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.
T75000	Mal-Pc	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Mal-Pc为基于酞菁和马来酰亚胺设计的多功能分子光敏剂。它能在癌细胞内与GSH反应，耗减GSH并抑制其聚集，进而增强ROS介导的PDT效果。
T28488	Quinuronium Sulfate Pirevan,Zothelone,Acaprin
	Quinuronium sulfate is a drug used to treat Babesia divergens infections in calves. It did not prevent treated animals from being disease carriers. It may also cause hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH).
T35454	γ-Glu-Cys (ammonium salt)
	γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelatins, the heavy metal detoxifying enzymes in plants.2
T36514	QD-394
	QD-394 is an inducer of reactive oxygen species (ROS) production.1It induces lipid peroxidation, increases in intracellular accumulation of reactive oxygen species (ROS), and decreases in the reduced glutathione (GSH) to oxidized GSH (GSSG) ratio in MIA PaCa-2 pancreatic cancer cells when used at concentrations ranging from 0.5 to 10 μM. QD-394 is cytotoxic to MIA PaCa-2, PANC-1, and BxPC-3 cancer cells (IC50s = 0.64, 0.34, and 0.9 μM, respectively). QD-394 acts synergistically with napabucasin ...
T74364	SDOX	Topoisomerase	DNA Damage/DNA Repair
	SDOX为Doxorubicin的前体药物，通过脂质体递送至肿瘤细胞内，在GSH过量释放条件下，触发DOX释放。该机制在不损害抗癌效果的同时，极大地降低了对正常组织的毒副作用。
T74895	Anti-inflammatory agent 31
	Anti-inflammatory agent 31 是一种穿心莲内酯衍生物，是一种抗炎剂 (anti-inflammatoryagent)。Anti-inflammatory agent 31 通过上游阻断PI3K/Akt 和ERK1/2 MAPK 激活来抑制NF-kB 激活。Anti-inflammatory agent 31 能够恢复细胞内 GSH 水平并对肝脏具有保护作用。
T38206	3-Cysteinylacetaminophen (trifluoroacetate salt) APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt)
	3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen.[1],[2] 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic doses of acetaminophen and in the presence and absence of hepatotoxicity.[3],[4] In mice, 3-cysteinylacetaminophen decreases renal glutathione (GSH) levels, an effect that can be blocked by the γ-glutamyl inhibitor acivicin.
T73421	CPT-Se3	Topoisomerase	DNA Damage/DNA Repair
	CPT-Se3为含硒的喜树碱前体活性分子，其杀癌和抗肿瘤效力显著。它通过降低GSH/GSSG比率及总硫醇水平，增加Hep G2细胞中ROS含量，触发癌细胞凋亡。CPT-Se3对HeLa、Hep G2、A549及SMMC-7721细胞线具备显着细胞毒性，IC50值介于2.19-4.7 μM。
T82972	Argininosuccinic acid disodium	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Argininosuccinic acid disodium 在尿素循环的第四步起关键作用，由ASL(精氨酸琥珀酸裂解酶)催化裂解生成精氨酸和富马酸。此外，该化合物能够降低GSH(还原型谷胱甘肽)浓度，并提升大脑皮层与纹状体中的活性氧产生。Argininosuccinic acid disodium 还可能导致脂质过氧化和蛋白质氧化，并在发育中的大鼠脑内触发氧化应激。
T37720	Difluorinated H2S Fluorescent Probe 1
	Difluorinated H2S probe 1 is a fluorescent probe for hydrogen sulfide (H2S).1It selectively fluoresces in the presence of H2S over Zn2+, Fe3+, S2O32-, ClO-, SO32-, H2O2, NO2-, cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) when used at a concentration of 1 μM. Difluorinated H2S probe 1 displays excitation/emission maxima of 365/450 nm, respectively. 1.Zhang, J., Gao, Y., Kang, X., et al.o,o-Difluorination of aromatic azide yields a fast-response fluorescent probe for H2S detection and...
T11357	Gamma-glutamylcysteine TFA γ-glutamylcysteine (TFA),Gamma-glutamylcysteine (TFA)	IL Receptor	Immunology/Inflammation
	Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes. Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx).
T61312	Antioxidant agent-3
	Antioxidant agent-3 (Compound 14q) 是一种抗氧化剂，具有有效的DPPH 自由基清除活性和ABTS+清除活性，IC50分别为 26.58 和 30.31 μM。Antioxidant agent-3 作用于 H2O2处理的 HepG2 细胞，可增加活性氧 (ROS)、超氧化物歧化酶 (SOD) 和谷胱甘肽 (GSH)，并减少乳酸脱氢酶(LDH)。
T38370	CAY10731
	CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm, respectively. CAY10731 is selective for H2S over glutathione (GSH), cysteine, H2O3-, SO3-, and H2O2 as well as tBuO and OH radicals. It has been used to detect H2S in rat hippocampal slices and nematodes.
T79388	Anticancer agent 154	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Anticanceragent 154 (Compound 8h) 增加活性氧水平、导致线粒体损伤，并诱导细胞凋亡和 DNA 损伤。此外，该化合物通过降低 GSH 和 GPX4 水平，增加脂质过氧化，进而诱导铁死亡。Anticanceragent 154 对多种癌细胞株（HT29、H1975、A549 及 MCF-7）显示抑制作用，IC50 值在 1.0-1.9 μM 范围。
T81485	Phoenixin-14 TFA PNX-14 TFA
	Phoenixin-14 (PNX-14) TFA 是具抗焦虑、心脏保护及神经保护效果的穿透大脑屏障神经肽。它通过上调GnRH受体mRNA调控垂体促性腺激素分泌，并促进胰岛素释放。此外，Phoenixin-14 TFA保护小鼠免受缺血/再灌注(IR)伤害，通过降低ROS、提高GSH减缓氧化应激。
T73422	CPT-Se4	Topoisomerase	DNA Damage/DNA Repair
	CPT-Se4为含硒前体活性分子的喜树碱(CPT)衍生物，对癌细胞具有较高杀伤力和抑制肿瘤生长效果。在降低GSH/GSSG比率和总硫醇的同时，CPT-Se4能够增加Hep G2细胞中的ROS水平，触发癌细胞凋亡。此化合物对HeLa、Hep G2、A549和SMMC-7721细胞系显示出显著的细胞毒性，IC50值范围为2.54-6.4 μM。
T36073	S-Acetyl-L-glutathione
	S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases ...
T69978	Brostallicin HCl
	Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent ...
T36610	(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
	(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde ...
T81233	S-(p-Nitrobenzyl)glutathione
	S-(p-Nitrobenzyl)glutathione 是一种竞争性谷胱甘肽酶(GGT)抑制剂，能被大鼠肾微粒体转化成相应的半胱氨酸衍生物。该化合物用于研究谷胱甘肽酶系统中GSH的代谢及其降解过程。
T83768	Zofenoprilat Zofenopril-SH,SQ 26,333
	Zofenoprilat是一种血管紧张素转换酶(ACE; IC50 = 8 nM for the rabbit lung enzyme)的抑制剂，同时也是前体药zofenopril的活性代谢产物。它能够抑制分离的豚鼠小肠中由血管紧张素I或缓激肽诱导的收缩(EC50s = 3 and 1 nM, respectively)。在人类脐静脉内皮细胞(HUVECs)中，Zofenoprilat (10 nM)降低基础内皮素-1分泌和一氧化氮(NO)生成，并阻止TNF-α诱导的活性氧种(ROS)增加以及谷胱甘肽(GSH)水平降低。Zofenoprilat (10 µM)保护初级人类心脏微血管内皮细胞免受多柔比星诱导的细胞毒性。此外，Zofenoprilat (10 µM)还能增加HUVECs中的硫化氢(H2S)生成，以及细胞的黏着、迁移和增殖。在以400 µM浓度使用时，它可以减少Langendorff分离的大鼠心脏灌流缺血再灌注损伤模型中的舒张末压和乳酸脱氢酶(LDH)释放。
T36507	Tetrachlorohydroquinone
	Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes. In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.

化合物

Cat.No: T74658

Glutathione Peroxidase

Cat.No: T80056

Synonym: GSH-Px,EC 1.11.1.9

Target: Glutathione Peroxidase

Cat.No: T7831

Target: Others, Transferase

N-Acetyl-D-cysteine

Cat.No: T38155

Target: Reactive Oxygen Species

Cat.No: T1052

Synonym: 二丙谷酰胺

Target: cholecystokinin

Cat.No: T21480

Synonym: Maleic acid, diethyl ester,DIETHYL MALEATE,马来酸二乙酯

Target: NF-κB

Cat.No: T14042

Synonym: 4-phenyl-2- propionamidotetralin

Target: Melatonin Receptor, MT Receptor

Cat.No: T70601

L-BUTHIONINE-(S,R)-SULFOXIMINE

Cat.No: T5371

Synonym: L-Butionine sulfoximine,丁硫氨酸-亚砜亚胺

Target: Others, Ferroptosis

Cat.No: T71439

Slingshot inhibitor D3

Cat.No: T28804

Synonym: JHN76359

Target: Others

Cat.No: T38968

Cat.No: T3646

Synonym: RSL3 1S,1S,3R-RSL3

Target: Ferroptosis, GPX, Glutathione Peroxidase

Topoisomerase II inhibitor 14

Cat.No: T77650

Target: Apoptosis, Antioxidant, Topoisomerase, NO Synthase

Monochlorobimane

Cat.No: T19028

Synonym: mBBr,Chlorobimane

Oxothiazolidinecarboxylic acid

Cat.No: T5365

Synonym: Oxothiazolidine carboxylate,Procysteine,丙半胱氨酸

Target: Antioxidant

MTP 131 acetate

Cat.No: T35689

Target: Others

Selenodiglutathione

Cat.No: T34605

Synonym: Seleno-di-glutathione,Bis(glutathione) selenide

Glutathione ethyl ester

Cat.No: T78616

Target: Reactive Oxygen Species

Eftansomatropin alfa

Cat.No: T82498

L-Glutathione, oxidized (sodium salt)

Cat.No: T36173

Cat.No: T74064

Cat.No: T69073

Cat.No: T75000

Target: Reactive Oxygen Species

Quinuronium Sulfate

Cat.No: T28488

Synonym: Pirevan,Zothelone,Acaprin

γ-Glu-Cys (ammonium salt)

Cat.No: T35454

Cat.No: T36514

Cat.No: T74364

Target: Topoisomerase

Anti-inflammatory agent 31

Cat.No: T74895

3-Cysteinylacetaminophen (trifluoroacetate salt)

Cat.No: T38206

Synonym: APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt)

Cat.No: T73421

Target: Topoisomerase

Argininosuccinic acid disodium

Cat.No: T82972

Target: Reactive Oxygen Species

Difluorinated H2S Fluorescent Probe 1

Cat.No: T37720

Gamma-glutamylcysteine TFA

Cat.No: T11357

Synonym: γ-glutamylcysteine (TFA),Gamma-glutamylcysteine (TFA)

Target: IL Receptor

Antioxidant agent-3

Cat.No: T61312

Cat.No: T38370

Anticancer agent 154

Cat.No: T79388

Target: Reactive Oxygen Species

Phoenixin-14 TFA

Cat.No: T81485

Synonym: PNX-14 TFA

Cat.No: T73422

Target: Topoisomerase

S-Acetyl-L-glutathione

Cat.No: T36073

Brostallicin HCl

Cat.No: T69978

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

Cat.No: T36610

S-(p-Nitrobenzyl)glutathione

Cat.No: T81233

Cat.No: T83768

Synonym: Zofenopril-SH,SQ 26,333

Tetrachlorohydroquinone

Cat.No: T36507

Cat. No.	Product Name	Target	Signaling Pathways
T1085	L-Glutathione reduced 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion	Ferroptosis; Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	L-Glutathione reduced (Glutathione) 属于天然三肽，存在与细胞中，是一种内源性抗氧化剂，可以清除氧自由基。L-Glutathione reduced 是某些酶的辅助因子，参与蛋白质二硫键重排并减少过氧化物。
T2800	L-Theanine L-茶氨酸,左旋茶氨酸	Apoptosis; Others	Apoptosis; Others
	L-Theanine 是一种存在于绿茶叶片中的非蛋白氨基酸物质，能阻断大脑中谷氨酸与谷氨酸受体结合，具有神经保护和抗氧化活性。它通过口服能抑制皮层神经元兴奋从而产生抗应激作用。
T7024	Qingyangshengenin 青阳参甙元,Qingyangshengenin A,Cynanchagenin	Others	Others
	Qingyangshengenin (Cynanchagenin) 是一种孕烷糖苷，是一种分离自Cychuchumot ophyllum(Asclepiadaceae) 的根中的 C21 类固醇糖苷配基。它具有抗癌作用。
TMS1461	Qingyangshengenin B 青阳参甙元B,青阳参苷元B,Otophylloside B	Beta Amyloid	Neuroscience
	Qingyangshengenin B (Otophylloside B) 是一种分离自 Qingyangshen 的 C-21 甾体苷。它能够在 mRNA 水平上抑制 Aβ 的表达来减少 Aβ 的沉积，对 Aβ 的毒性有保护作用。它具有抗癫痫作用。
TN5301	Qingyangshengenin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside
	Qingyangshengenin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5301，CAS号为 1808159-02-5。
TN4432	Liangshanin A	Others	Others
	Liangshanin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4432，CAS号为 122717-54-8。
TN5309	Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside
	Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5309，CAS号为 1186628-87-4。
TN5094	Tangshenoside I	Glucokinase	Metabolism
	Tangshenoside I might be a potential bioactive marker related to the hematopoietic and immunologic functions of Codonopsis Radix, which could be recommended as the index compound. It has α-glucosidase inhibition activity.
TMS1460	Qingyangshengenin A	Others	Others
	Qingyangshengenin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TMS1460，CAS号为 106644-33-1。
TN5306	Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside
	Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5306，CAS号为 1186628-88-5。
Fr14207	(-)-Isopulegol	Others	Others
	(-)-Isopulegol 具有抗氧化和神经活性特性。它还具有由异胡薄荷醇诱导的胃保护作用，似乎至少部分由内源性前列腺素介导，K+ATP 通道开放和与 GSH 相关的抗氧化特性增加。
T5S1097	Neferine (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱	Apoptosis; NF-κB; Autophagy	Apoptosis; Autophagy; NF-κB
	Neferine ((-)-Neferine) 是一种双苄基异喹啉类生物碱，可强效抑制NF-κB 激活，具有抗肿瘤活性。
T6S0735	Flavokawain B 黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone	Apoptosis; Others	Apoptosis; Others
	Flavokawain B (Flavokavain B) 是从卡瓦醉椒的根提取物中，分离出的查尔酮。它是一种凋亡诱导剂，可抑制各种癌细胞株生长。它以极低的无毒浓度抑制人脑内皮细胞的迁移和血管形成，具有抗血管生成活性。
T60789	L-Cystine dihydrochloride
	L-Cystine dihydrochloride 是合成谷胱甘肽 (GSH) 的含硫前体。L-Cystine dihydrochloride 的稳态对谷胱甘肽的功能很重要。L-Cystine dihydrochloride 可用作细胞培养组分。
T82046	Irisquinone
	Irisquinone，一种具有抗癌活性的天然产物，同时作为癌症放射增敏剂。该化合物通过降低GSH水平并抑制DNA单链断裂修复，展现其药理作用。
TN4779	Physalin O	IκB/IKK	NF-κB
	Physalin O possesses anti-inflammatory activity, it exhibited conjugating abilities with GSH and also showed significant nitric oxide (NO) production inhibiting activities.
T5S0313	Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside Liquiritin apioside,甘草苷元-7-O-D-芹糖-4'-O-D-葡萄糖苷	Others; TNF	Apoptosis; Others
	Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress, might be as protective agent against epithelial
T83915	Norbixin hydrate
	Norbixin是一种在B. orellana中发现的类胡萝卜素，具有多样的生物活性。在无细胞测试中，它与过氧化物酶体增殖物激活受体γ (PPARγ)结合（Ki = 1.15 µM）。在心脑血管代谢综合征大鼠模型中，Norbixin (47.7 mg/kg) 能够减轻高血糖、高胰岛素血症和胰岛素抗性，降低血清脂质水平及心脏中硫代巴比妥酸反应性物质（TBARS）和谷胱甘肽（GSH）的水平。在胆固醇诱导的动脉粥样硬化兔模型中，它降低氧化型LDL和主动脉蛋白氧化水平，并减少动脉粥样硬化面积。Norbixin（每天0.1和1 mg/kg）减少汞诱导的大鼠肝细胞和白细胞DNA损伤。此外，它还能预防与年龄相关的黄斑变性（AMD）Abca4-/- Rdh8-/-小鼠模型中的光感受器退化。

天然产物

L-Glutathione reduced

Cat.No: T1085

Synonym: 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase

Cat.No: T2800

Synonym: L-茶氨酸,左旋茶氨酸

Target: Apoptosis, Others

Qingyangshengenin

Cat.No: T7024

Synonym: 青阳参甙元,Qingyangshengenin A,Cynanchagenin

Target: Others

Qingyangshengenin B

Cat.No: TMS1461

Synonym: 青阳参甙元B,青阳参苷元B,Otophylloside B

Target: Beta Amyloid

Qingyangshengenin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside

Cat.No: TN5301

Cat.No: TN4432

Target: Others

Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside

Cat.No: TN5309

Tangshenoside I

Cat.No: TN5094

Target: Glucokinase

Qingyangshengenin A

Cat.No: TMS1460

Target: Others

Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside

Cat.No: TN5306

Cat.No: Fr14207

Target: Others

Cat.No: T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱

Target: Apoptosis, NF-κB, Autophagy

Cat.No: T6S0735

Synonym: 黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone

Target: Apoptosis, Others

L-Cystine dihydrochloride

Cat.No: T60789

Cat.No: T82046

Cat.No: TN4779

Target: IκB/IKK

Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside

Cat.No: T5S0313

Synonym: Liquiritin apioside,甘草苷元-7-O-D-芹糖-4'-O-D-葡萄糖苷

Target: Others, TNF

Norbixin hydrate

Cat.No: T83915

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