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Search Results for " flt-3 "

Targets Recommended: Others PROTACs

21

抑制剂 & 化合物

1

天然产物

71

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T12555	PROTAC FLT-3 degrader 1	Others; PROTACs	Others; PROTAC
	PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.
T11298	FLT3-IN-3	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	FLT3-IN-3 是 FLT3抑制剂，能够抑制 FLT3 WT (IC50:13 nM) 和 FLT3 D835Y (IC50:8 nM) 。
T1938	FLT3-IN-2	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	FLT3-IN-2 是 FLT3 抑制剂(IC50＜1 μM)。
T11299	FLT3-IN-4 FLT3 inhibitor 9u	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	FLT3-IN-4 (FLT3 inhibitor 9u) 是一种口服有效的 Fms 样酪氨酸受体激酶 3 (FLT3; IC50= 7 nM) 抑制剂，可用于急性髓性白血病的研究。
T27011	CHMFL-FLT3-122 CHMFLFLT3122,CHMFL FLT3 122	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	CHMFL-FLT3-122 是一种强效口服 FLT3 激酶抑制剂，用于治疗 FLT3-ITD 阳性急性髓性白血病。CHMFL-FLT3-122能显著抑制 MV4-11细胞异种移植模型（50 mg/kg）的肿瘤生长，且在体内无明显毒性。
T11300	FLT3-IN-6	Others	Others
	FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.
T24067	Flt3 Inhibitor IV Flt3 Inhibitor-IV,Flt3-IN-IV
	Flt3 Inhibitor IV is a potent ATP-competitive Flt3 inhibitor.
T72407	c-Met/MEK1/Flt-3-IN-1
	Antiproliferative against-3 具有良好的抗癌细胞增殖活性，对 Hela、A549 和 MCF-7 的细胞的 IC50值分别为 0.21 µM、0.39 µM 和 0.33 µM。Antiproliferative against-3 (comp 33) 剂量依赖性的诱导 A549 细胞的凋亡，并将细胞阻滞在 G1 期。
T8326	BMS-2 1-(4-氟苯基)-N-[3-氟-4-(1H-吡咯并[2,3-B]吡啶-4-基氧基)苯基]-1,2-二氢-2-氧代-3-吡啶甲酰胺	VEGFR; FLT; c-Met/HGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	BMS-2 是 Met/Flt-3/VEGFR2 酪氨酸激酶抑制剂。
T2272	BPR1J-097 BPR1J097	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	BPR1-J097 是新型的、强效的FLT3抑制剂 (IC50:11 nM)。
T4261	BPR1J-097 hydrochloride (1327167-19-0(free base))	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	BPR1J-097 hydrochloride (1327167-19-0(free base)) 是一种新型小分子 FLT-3抑制剂(IC50=11±7 nM)，具有很好的体内抗肿瘤活性。
T1836	AZD2932	VEGFR; FLT; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	AZD2932是一种多靶点激酶抑制剂，细胞试验中能够抑制 VEGFR2 (IC50:8 nM)，PDGFβ (IC50:4 nM)，PDGFβ (IC50:7 nM) 和 PDGFβ (IC50:9 nM)。
T8496	MAZ51	Apoptosis; VEGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	MAZ51 是一种 VEGFR-3酪氨酸激酶的选择性抑制剂。它抑制 VEGF-C 诱导的 VEGFR-3 激活，而没有阻断 VEGF-C 介导的 VEGFR2 刺激。它阻止增殖并诱导多种肿瘤细胞凋亡，具有抗肿瘤活性。
T4053	AST 487 NVP-AST 487	VEGFR; FLT; c-RET; Bcr-Abl; c-Kit	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	AST 487 (NVP-AST 487) 是 RET 激酶抑制剂 (IC50:880 nM)，能够抑制 RET 自磷酸化，及下游效应器激活，也抑制 Flt-3 (IC50:520 nM)。
T6092	Sapitinib 沙普替尼,AZD-8931	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Sapitinib (AZD-8931) 是可逆的 ATP 竞争型 EGFR 抑制剂，对 EGFR、ErbB2 和 ErbB3的IC50值分别为4、3 和 4 nM。
T2624	OSI-930 OSI 930,噻尔非尼	Apoptosis; c-Fms; Raf; VEGFR; FLT; CSF-1R; Src; c-Kit	Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
	OSI-930 是 Kit，KDR 和 CSF-1R (c-Fms)的口服选择性抑制剂，IC50分别为 80 nM，9 nM 和 15 nM。它具有抗肿瘤活性，靶向肿瘤中的癌细胞增殖和血管生成。它还适度抑制 Flt-1，c-Raf 和 Lck，并且对 PDGFRα/β，Flt-3和 Abl 具有较弱的抑制活性。
T2514	Linifanib 利尼伐尼,ABT-869,RG3635,AL-39324	Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
	Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂，具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂，阻断miR-10b 的生物合成。
T22288	(1E)-CFI-400437 dihydrochloride CFI-400437 dihydrochloride	PLK	Cell Cycle/Checkpoint
	(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) 是一种选择性和有效的 polo 样激酶 4 (PLK4) 抑制剂，IC50为 0.6 nM。它还抑制 Aurora A、 Aurora B、 KDR 和 FLT-3，IC50分别为 0.37、0.21、0.48 和 0.18 μM，具有抗增殖活性。
T39818	Desmorpholinyl Quizartinib-PEG2-COOH Desmorpholinyl Quizartinib-PEG2-COOH
	Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
T19689	Raluridine FddClUrd,935U-83,FCU,DRG-0215,BW-935U-83
	Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-f
T68389	LY2457546
	LY2457546 is a potent and orally bioavailable inhibitor of multiple receptor tyrosine kinases involved in angiogenic and tumorigenic signalling. LY2457546 demonstrates potent activity against targets that include VEGFR2 (KDR), PDGFRβ, FLT-3, Tie-2 and members of the Eph family of receptors. In vivo, LY2457546 inhibited VEGF-driven autophosphorylation of lung KDR in the mouse and rat in a dose and concentration dependent manner. LY2457546 was well tolerated and exhibited efficacy in a 13762 synge...

化合物

PROTAC FLT-3 degrader 1

Cat.No: T12555

Target: Others, PROTACs

Cat.No: T11298

Target: FLT

Cat.No: T1938

Target: FLT

Cat.No: T11299

Synonym: FLT3 inhibitor 9u

Target: FLT

CHMFL-FLT3-122

Cat.No: T27011

Synonym: CHMFLFLT3122,CHMFL FLT3 122

Target: FLT

Cat.No: T11300

Target: Others

Flt3 Inhibitor IV

Cat.No: T24067

Synonym: Flt3 Inhibitor-IV,Flt3-IN-IV

c-Met/MEK1/Flt-3-IN-1

Cat.No: T72407

Cat.No: T8326

Synonym: 1-(4-氟苯基)-N-[3-氟-4-(1H-吡咯并[2,3-B]吡啶-4-基氧基)苯基]-1,2-二氢-2-氧代-3-吡啶甲酰胺

Target: VEGFR, FLT, c-Met/HGFR

Cat.No: T2272

Synonym: BPR1J097

Target: FLT

BPR1J-097 hydrochloride (1327167-19-0(free base))

Cat.No: T4261

Target: FLT

Cat.No: T1836

Target: VEGFR, FLT, PDGFR, c-Kit

Cat.No: T8496

Target: Apoptosis, VEGFR

Cat.No: T4053

Synonym: NVP-AST 487

Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit

Cat.No: T6092

Synonym: 沙普替尼,AZD-8931

Target: EGFR

Cat.No: T2624

Synonym: OSI 930,噻尔非尼

Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit

Cat.No: T2514

Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324

Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy

(1E)-CFI-400437 dihydrochloride

Cat.No: T22288

Synonym: CFI-400437 dihydrochloride

Target: PLK

Desmorpholinyl Quizartinib-PEG2-COOH

Cat.No: T39818

Synonym: Desmorpholinyl Quizartinib-PEG2-COOH

Cat.No: T19689

Synonym: FddClUrd,935U-83,FCU,DRG-0215,BW-935U-83

Cat.No: T68389

Cat. No.	Product Name	Target	Signaling Pathways
T15542	Hypothemycin	Others	Others
	Hypothemycin is a fungal polyketide and is a multikinase inhibitor (Kis: 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8.4/2.4 μM for VEGFR2/VEGFR1, MEK1/MEK2, FLT-3, PDGFRβ/PDGFRα, and ERK1/ERK2, respectively).

天然产物

Cat.No: T15542

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His) VEGFR-3,PCL,FLT41,VEGF Receptor 3...	Human	HEK293 Cells
	VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1.
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Flt-4,VEGFR-3,Chy,fms related tyrosine kin...	Mouse	HEK293 Cells
	VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPK-00445	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) PCL,PCLFLT41,VEGFR3,FLT-4,LMPH1A,...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.4 k...
TMPK-00446	VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated PCL,FLT-41,LMPH1A,FLT-4,VEGFR3,PC...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPY-01069	VEGFR3/FLT4 Protein, Human, Recombinant (hFc) FLT41,fms related tyrosine kinase 4,VEGF Receptor <...	Human	HEK293 Cells
	VEGFR3/FLT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.3 kDa and the accession number is P35916-1.
TMPK-00523	FLT3 Protein, Cynomolgus, Recombinant (hFc) FLT-3,FLK2,STK-1,CD135	Cynomolgus	HEK293 Cells
	FLT3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.58 kDa and the accession number is A0A2K5VQ48.
TMPY-06620	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated PCL,VEGFR-3,LMPH1A,fms related tyrosine kinase 4,	Human	HEK293 Cells
	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 87.80 kDa and the accession number is NP_002011.2.
TMPK-00416	FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated STK-1,FLK2,CD135,FLT-3	Human	CHO Cells
	FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in CHO mammalian cells with C-His-Avi tag. The predicted molecular weight is 61.20 kDa and the accession number is P36888-1.
TMPY-03704	FLT3 Protein, Mouse, Recombinant (His) wmfl,Flk-2,Flk2,Flt-3,CD135,B2	Mouse	HEK293 Cells
	FLT3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.4 kDa and the accession number is EDL05832.1.
TMPY-01937	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) VEGFR-3,fms related tyrosine kinase 4,VEGFR3	Mouse	HEK293 Cells
	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P35917-1.
TMPK-00929	FLT3 Protein, Mouse, Recombinant (hFc) FL,FLT3LG,Flt3L,SL cytok...	Mouse	HEK293 Cells
	Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.78 kDa and the accession number is Q00342.
TMPK-00125	FLT3 Ligand Protein, Human, Recombinant (hFc) FLT3LG,FL,Flt3 ligand,SL...	Human	HEK293 Cells
	Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Ligand Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.8 kDa and the accession number is P49771-1.
TMPY-06986	FGF-8b Protein, Human, Recombinant NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132	Mesothelin Protein, Human, Recombinant MPF,SMRP,Mesothelin	Human	HEK293 Cells
	Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935	CD47 Protein, Human, Recombinant (aa 1-139, His) MER6,CD47 molecule,IAP,OA3	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc) Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191	CD47 Protein, Human, Recombinant, Biotinylated CD47 molecule,MER6,OA3,IAP	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-04683	CD47 Protein, Human, Recombinant MER6,CD47 molecule,OA3,IAP	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His) AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His) L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells) interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-01180	CD86 Protein, Human, Recombinant (His) CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His) PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...	Human	HEK293 Cells
	Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-01897	PRSS3 Protein, Human, Recombinant (His) PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His) NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-04298	CDCP1 Protein, Human, Recombinant (His) TRASK,CD318,CUB domain containing protein 1,SIMA1	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His) HNT,NTRI,IGLON2,neurotrimin	Human	HEK293 Cells
	HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-00480	NCAM1 Protein, Human, Recombinant (His) neural cell adhesion molecule 1,CD56,MSK39,NCAM	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc) CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPY-03621	EphB2 Protein, Mouse, Recombinant (hFc) Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPJ-01288	KLF6 Protein, Human, Recombinant CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...	Human	Baculovirus Insect Cells
	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST) SET and MYND domain containing 3,ZMYND1,KMT3	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03149	CDCP1 Protein, Human, Recombinant (mFc) TRASK,SIMA135,CD318,CUB domain containing ...	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPK-00401	FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPK-00398	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Fibroblast growth factor receptor 2,CD332,...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPJ-00391	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-05514	RANK/TNFRSF11A Protein, Human, Recombinant (mFc) OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-00276	PLGF/PGF Protein, Human, Recombinant (mFc) placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2	Human	HEK293 Cells
	PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-03960	COL9A1 Protein, Human, Recombinant (His) EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...	Human	HEK293 Cells
	COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPY-04015	COL9A1 Protein, Human, Recombinant (mFc) DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...	Human	HEK293 Cells
	COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPY-06411	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated CD357,GITR-D,tumor necrosis factor receptor superfa...	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPK-00400	FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSAM,CD3...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3.
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Keratinocyte growth factor receptor,K-sam,BEK,FGFR2 β (IIIb)...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-03705	VEGF164 Protein, Canine, Recombinant 血管内皮生长因子,vascular endothelial growth factor A	Canine	HEK293 Cells
	VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPY-04157	RANK/TNFRSF11A Protein, Human, Recombinant (His) ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor supe...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3.
TMPK-00729	Siglec-6 Protein, Human, Recombinant (His & Avi) SIGLEC6,OBBP1,CD327,CD33L1,CD...	Human	HEK293 Cells
	Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
TMPY-05590	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated NCAM,MSK39,CD56,neural cell adhesion molecule 1	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3.
TMPJ-00390	FGFR2IIIb Protein, Human, Recombinant (hFc) FGFR2,FGFR2 beta,FGFR2 β,FGFR2IIIb,KGFR,FGF R2b,BFR-1,FGFR2b...	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.
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重组蛋白

VEGFR3/FLT4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00949

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01936

Species: Mouse

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00445

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated

Cat.No: TMPK-00446

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01069

Species: Human

Expression System: HEK293 Cells

FLT3 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPK-00523

Species: Cynomolgus

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06620

Species: Human

Expression System: HEK293 Cells

FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00416

Species: Human

Expression System: CHO Cells

FLT3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03704

Species: Mouse

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01937

Species: Mouse

Expression System: HEK293 Cells

FLT3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00929

Species: Mouse

Expression System: HEK293 Cells

FLT3 Ligand Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00125

Species: Human

Expression System: HEK293 Cells

FGF-8b Protein, Human, Recombinant

Cat.No: TMPY-06986

Species: Human

Expression System: E. coli

Mesothelin Protein, Human, Recombinant

Cat.No: TMPY-00132

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (aa 1-139, His)

Cat.No: TMPY-04935

Species: Human

Expression System: HEK293 Cells

Neuropilin-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03763

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05191

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant

Cat.No: TMPY-04683

Species: Human

Expression System: HEK293 Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00072

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, His)

Cat.No: TMPY-05748

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04142

Species: Human

Expression System: HEK293 Cells

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-01099

Species: Human

Expression System: HEK293 Cells

CD86 Protein, Human, Recombinant (His)

Cat.No: TMPY-01180

Species: Human

Expression System: HEK293 Cells

Periostin/OSF-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01020

Species: Human

Expression System: HEK293 Cells

PRSS3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01897

Species: Human

Expression System: HEK293 Cells

Neuropilin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00892

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04298

Species: Human

Expression System: HEK293 Cells

HNT/NTM Protein, Human, Recombinant (His)

Cat.No: TMPY-00357

Species: Human

Expression System: HEK293 Cells

NCAM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00480

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, hFc)

Cat.No: TMPK-00447

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03621

Species: Mouse

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

Cat.No: TMPJ-01288

Species: Human

Expression System: E. coli

EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

Cat.No: TMPY-04386

Species: Human

Expression System: Baculovirus Insect Cells

SMYD3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01268

Species: Human

Expression System: Baculovirus Insect Cells

CDCP1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03149

Species: Human

Expression System: HEK293 Cells

FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00401

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Cat.No: TMPK-00398

Species: Human

Expression System: HEK293 Cells

FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

Cat.No: TMPJ-00391

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

Cat.No: TMPY-05514

Species: Human

Expression System: HEK293 Cells

PLGF/PGF Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00276

Species: Human

Expression System: HEK293 Cells

COL9A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03960

Species: Human

Expression System: HEK293 Cells

COL9A1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04015

Species: Human

Expression System: HEK293 Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06411

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00400

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPK-00399

Species: Human

Expression System: HEK293 Cells

VEGF164 Protein, Canine, Recombinant

Cat.No: TMPY-03705

Species: Canine

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (His)

Cat.No: TMPY-04157

Species: Human

Expression System: HEK293 Cells

Siglec-6 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00729

Species: Human

Expression System: HEK293 Cells

NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05590

Species: Human

Expression System: HEK293 Cells

FGFR2IIIb Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00390

Species: Human

Expression System: HEK293 Cells

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