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Search Results for " fgfr3 "

52

抑制剂 & 化合物

23

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T73146	FGFR3-IN-5
	FGFR3-IN-5 是一种有效的选择性 FGFR3抑制剂，对 FGFR3、FGFR2 和 FGFR1的 IC50值分别为 3、44、和 289 nM。FGFR3-IN-5 可用于癌症的研究。
T64107	FGFR3-IN-1
	FGFR3-IN-1 (compound 1) 是一种成纤维细胞生长因子受体 (FGFR) 抑制剂，可抑制FGFR1 (IC50: 40 nM)，FGFR2 (IC50: 5.1 nM) 和 FGFR3 (IC50: 12 nM)。FGFR3-IN-1 能够用于研究膀胱癌。
T82405	FGFR3-IN-6	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR3-IN-6为FGFR3选择性抑制剂，具有低于350 nM 的IC50，适用于癌症研究领域。
T64215	FGFR3-IN-2
	FGFR3-IN-2 (compound 18b) 是一种有效的、选择性的 FGFR3 抑制剂，能够抑制 FGFR3 (IC50: 4.1 nM) 和 VEGFR2 (IC50: 570 nM)。FGFR3-IN-2 能够用于研究膀胱癌。
T73145	FGFR3-IN-4
	FGFR3-IN-4 是一种选择性的 FGFR3抑制剂，IC50值小于 50 nM。FGFR3-IN-4 对 FGFR3的选择性至少比FGFR1高 10 倍。
T82404	FGFR3-IN-7	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR3-IN-7为高选择性FGFR3抑制剂，显示出小于350 nM 的IC50效价，主要用于癌症相关研究。
T8492	BO-264	Apoptosis; FGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	BO-264 是一种有口服活性的转化酸性卷曲螺旋 3 抑制剂，可特异性阻断 FGFR3-TACC3融合蛋白的功能。它诱导纺锤体检查点依赖的有丝分裂阻滞，DNA 损伤和细胞凋亡，具有广谱抗肿瘤活性。
T6479	Dovitinib lactate hydrate Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258	VEGFR; FGFR; FLT; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂，抑制 FLT3，c-Kit，FGFR1/3，VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1，2，8/9，10/13/8，27/210 nM。
T16364	Infigratinib phosphate NVP-BGJ398 phosphate,BGJ-398 phosphate	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Infigratinib phosphate (BGJ-398 phosphate) 是 FGFR 抑制剂，对 FGFR1，FGFR2 和 FGFR3 的 IC50 分别为0.9，1.4 和 1 nM，比对 FGFR4 和 VEGFR2 的抑制性高40倍，对 Abl，Fyn，Kit，Lck 和 Lyn 几乎无活性。
TQ0228	Derazantinib ARQ-087	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Derazantinib (ARQ-087) 是一种有效的，ATP 竞争型的，具有口服活性的酪氨酸激酶抑制剂，能够抑制软骨细胞FGFR1 (IC50:4.5 nM)、FGFR2 (IC50:1.8 nM)、FGFR3 (IC50:4.35nM)。
T7104	Dovitinib lactate CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate	VEGFR; FGFR; FLT; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Dovitinib lactate (TKI-258 lactate) 是一种多靶点的酪氨酸激酶抑制剂，抑制FLT3，c-Kit，FGFR1/3，VEGFR1/2/3和PDGFRα/β的IC50值分别为 1，2，8/9，10/13/8，27/210 nM。
T12401	Pemigatinib INCB054828	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Pemigatinib (INCB054828) 是一种口服具有活力的，选择性的 FGFR 抑制剂，能够作用于 FGFR1 (IC50:0.4 nM)，FGFR2 (IC50:0.5 nM)，FGFR3 (IC50:1.2 nM)，FGFR4 (IC50:30 nM)，有用于胆管癌的潜力。
T6024	Zoligratinib FF284,CH5183284,Debio 1347	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Zoligratinib (CH5183284) 是一种口服具有活力的，选择性的FGFR 抑制剂，能够抑制FGFR1 (IC50:9.3 nM)，FGFR2 (IC50:7.6 nM)，FGFR3 (IC50:22 nM)，FGFR4 (IC50:290 nM)。
T61304	FGFR2-IN-1	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR2-IN-1是一种 FGFR 抑制剂，对 FGFR1、FGFR2和FGFR3具有抑制作用， IC50 分别为460、140和2200 nM。FGFR2-IN-1 可用于研究与 FGFR2 相关的癌症。
T2361	LY2874455 LY 2874455,LY-2874455	VEGFR; FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	LY2874455 是pan-FGFR 抑制剂，能够抑制FGFR1 (IC50:2.8 nM)，FGFR2 (IC50:2.6 nM)，FGFR3 (IC50:6.4 nM)，FGFR4 (IC50:6 nM)。
T3466	FIIN-3	EGFR; FGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	FIIN-3 是FGFR 的不可逆抑制剂，对FGFR1、FGFR2、FGFR3和FGFR4的IC50值分别为13.1、21、31.4和35.3 nM。
T76877	Vofatamab RG-7444,B-701,MFGR-1877S	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Vofatamab (B-701) 是一种全人源靶向 FGFR3 的单克隆抗体。Vofatamab 具有潜在的抗癌抗肿瘤活性，常与其他化合物联用来治疗癌症。
T6028	PF 477736 PF 00477736,PF-477736,PF-736,PF-00477736,PF477736	c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂，Ki 值为0.49 nM。它也是Chk2抑制剂，Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。
T1777	Nintedanib BIBF 1120,Intedanib,尼达尼布	VEGFR; FGFR; FLT; PDGFR; Src	Angiogenesis; Tyrosine Kinase/Adaptors
	Nintedanib (Intedanib) 是一种三重血管激酶抑制剂，抑制 VEGFR1、VEGFR2、VEGFR3 (IC50=34/13/13 nM)，FGFR1、FGFR2、FGFR3 (IC50=69/37/108 nM)，PDGFRα、PDGFRβ (IC50=59/65 nM)。Nintedanib 具有抗肿瘤活性，通过抑制血管生成来抑制肿瘤生长。
T1948	AZD4547	VEGFR; FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	AZD4547 是FGFR 家族抑制剂，能够作用于FGFR1 (IC50:0.2 nM)，FGFR2 (IC50:2.5 nM)，FGFR3 (IC50:1.8 nM) 和FGFR4 (IC50:165 nM)。
T6435	CCT129202 2-[4-[6-氯-2-(4-二甲基氨基苯基)-3H-咪唑并[4,5-B]吡啶-7-基]哌嗪-1-基]-N-(噻唑-2-基)乙酰胺	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	CCT129202 是一种 ATP 竞争性泛极光激酶抑制剂，作用于 Aurora A、Aurora B 和 Aurora C，IC50 分别为 0.042 μM、0.198 μM 和 0.227 μM。
T6836	FIIN-2	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FIIN2 是一种 FGFR 的不可逆抑制剂，能够抑制 FGFR1 (IC50:3.1 nM)，FGFR2 (IC50:4.3 nM)，FGFR3 (IC50:27 nM) 和 FGFR4 (IC50:45 nM)。
T1975	Infigratinib BGJ-398,NVP-BGJ398	Apoptosis; FGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Infigratinib (NVP-BGJ398) 是一种 FGFR 家族抑制剂，抑制 FGFR1，FGFR2，FGFR3和 FGFR4的 IC50分别为 0.9 nM，1.4 nM，1 nM，60 nM。
T5122	Alofanib RPT835	Apoptosis; FGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Alofanib (RPT835) 是一种高效和选择性的成纤维细胞生长因子受体2的变构抑制剂，具有抗癌和抗血管生成活性。
TQ0015	PRN1371	c-Fms; FGFR; CSF-1R	Angiogenesis; Tyrosine Kinase/Adaptors
	PRN1371 是一种高效的、选择性的FGFR1-4和CSF1R 抑制剂，对FGFR1，FGFR2，FGFR3，FGFR4 和 CSF1R 的IC50值分别为 0.6，1.3，4.1，19.3 和 8.1 nM。
T5001	Nintedanib esylate Intedanib,乙磺酸尼达尼布,BIBF 1120 (esylate),尼达尼布乙磺酸盐,Nintedanib Ethanesulfonate Salt,BIBF 1120	VEGFR; FGFR; PDGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Nintedanib esylate (BIBF 1120 esylate) 是一种有效的三重血管激酶抑制剂，能够抑制 VEGFR1 (IC50:34 nM)、VEGFR2 (IC50:13 nM)、VEGFR3 (IC50:13 nM)，FGFR1 (IC50:69 nM)、FGFR2 (IC50:37 nM)、FGFR3 (IC50:108 nM)，PDGFRα (IC50:59 nM)、PDGFRβ (IC50:65 nM)。
T2609	Masitinib AB1010,马赛替尼	Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit，IC50=200 nM)，它还抑制PDGFRα/β(IC50s=540/800 nM)，Lyn(对 LynB 的IC50=510 nM)，Lck，较小程度上抑制FGFR3和FAK。它有抗增殖，促凋亡活性，且毒性低。
T37426	FIIN-1 FGFR irreversible inhibitor-1	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FIIN-1 (FGFR irreversible inhibitor-1) 是一种不可逆具有选择性的 FGFR 抑制剂，对 FGFR1、FGFR2、FGFR3、FGFR4、 Flt1、Flt14 的 Kd 分别为 2.8、6.9、5.4、120 ，32和120 nM。FIIN-1 对FGFR1、FGFR2、FGFR3和FGFR4 具有抑制作用， IC50 分别是 9.2，6.2，11.9 和 189 nM。
T2347	BLU9931	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	BLU9931 是高度选择性的，不可逆的成纤维细胞生长因子受体 4 抑制剂，其 IC50=3 nM，Kd=6 nM，具有抗肿瘤作用。
T64125	FGFR-IN-8
	FGFR-IN-8 一种高效的、口服具有活力的 FGFR 抑制剂，可抑制野生型和突变型 FGFR。 FGFR-IN-8 能够作用于 FGFR1 (IC50<0.5 nM)、V564F-FGFR2 (IC5016: 189.1 nM)、N549H-FGFR2 (IC50<0.5 nM)、V555M-FGFR3 (IC50: 22.6 nM)、FGFR3 (IC50<0.5 nM) 和 FGFR 4 (IC50: 7.30 nM)。FGFR-IN-8 能够诱导癌细胞凋亡（apoptosis），表现出抗癌效果。
T74462	SNIPER(TACC3)-11
	SNIPER(TACC3)-11是一种针对FGFR3-TACC3的有效抑制剂，能够降低FGFR3-TACC3蛋白水平，并抑制FGFR3-TACC3阳性癌细胞增殖。
T5473	ASP5878 ASP-5878	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂，具有口服活性，具有潜在的抗肿瘤作用。
T76367	VSPPLTLGQLLS
	VSPPLTLGQLLS为一种针对FGFR3的小肽抑制剂，属于肽P3类，具有抑制FGFR3磷酸化的能力。该化合物能阻断9-cisRA诱导的气管淋巴管生成，并抑制淋巴内皮细胞(LEC)的增殖、迁移和小管形成。
T77145	Recifercept
	Recifercept (TA-46) 是一种溶解性重组FGFR3分子，能够作为诱饵/配体陷阱，降低与突变FGFR3受体结合的成纤维细胞生长因子数量，用于研究软骨发育不全。
T72749	E7090 succinate
	E7090 succinate 是具有口服活性的、选择性的、有效的 FGFR1/2/3抑制剂，其对 FGFR1/2/3/4 的 IC50值分别为 0.71 nM、0.50 nM、1.2 nM 和120 nM。
T76368	VSPPLTLGQLLS TFA
	VSPPLTLGQLLS TFA为FGFR3小肽抑制剂，属于肽P3类，可阻断FGFR3磷酸化。该化合物能够抑制9-cisRA诱导的气管淋巴管生成，同时抑止淋巴内皮细胞(LEC)的增殖、迁移及小管形成。
T10997	Derazantinib Racemate ARQ-087 Racemate	Others	Others
	Derazantinib Racemate (ARQ-087 Racemate) 是 Derazantinib 的外消旋体。Derazantinib 是一种有效的，ATP 竞争型的，具有口服活性的酪氨酸激酶抑制剂，能够抑制软骨细胞 FGFR1 (IC50:4.5 nM)、FGFR2 (IC50:1.8 nM)、FGFR3 (IC50:4.5nM)。
T76277	Vosoritide
	Vosoritide (BMN 111) 为改良重组CNP (C型钠尿肽) 类似物，作用于NPR-B (B型钠尿肽受体)，能有效降低FGFR3 (成纤维细胞生长因子受体 3) 活性，主要应用于软骨症和侏儒症研究领域。
T3726	Erdafitinib 厄达替尼,JNJ-42756493	Apoptosis; FGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Erdafitinib (JNJ-42756493) 是一种喹喔啉衍生物，是一种具有口服活性的FGFR 家族抑制剂，抑制FGFR1/2/3/4活性的IC50分别为1.2、 2.5、3.0和5.7 nM。
T62652	CPL304110
	CPL304110 是一种口服具有活力的、选择性的、有效的成纤维细胞生长因子受体 FGFR (1-3) 的抑制剂，能够作用于 FGFR1 (IC50: 0.75 nM)、 FGFR2 (IC50: 0.5 nM)、FGFR3 (IC50: 3.05 nM) 。
T62682	FGFR4-IN-10
	FGFR4-IN-10 (compound 5a) 是一种选择性的、有效的 FGFR4 抑制剂 (IC50: 70.7 nM)。FGFR4-IN-10 不能抑制其他 FGFR 家族成员 (即 FGFR1、FGFR2 和 FGFR3)。
T73316	FGFR-IN-9
	FGFR-IN-9 是一种有效的、可逆的、具有口服活性的FGFR 抑制剂，对FGFR4WT、FGFR3、FGFR4V550L、FGFR2 和FGFR1的IC50分别为 17.1、29.6、30.7、46.7 和 64.3 nM。
T39001	FGFR-IN-1
	FGFR-IN-1 is a highly effective inhibitor targeting the Fibroblast Growth Factor Receptor (FGFR) group, comprising FGFR1, FGFR2, and FGFR3, with an impressive inhibitory concentration (IC 50) of less than 100 nM (US20130338134A1, example 219).
T62653	FGFR-IN-2
	FGFR-IN-2 (compound 1) 是一种有效的 FGFR 抑制剂，能够作用于 FGFR1 (IC50: 7.3 nM)、FGFR2 (IC50: 4.3 nM)、FGFR3 (IC50: 7.6 nM) 和 FGFR4 (IC50: 11 nM)。FGFR-IN-2 具有潜力进行癌症研究。
T70276	Roridin E
	Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFRβ, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 μM, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM). It also inhibits proliferation in a panel of additional cancer cell lines (IC50s = <0.01 μM).
T79257	FGFR-IN-11	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	FGFR-IN-11（compound I-5）是一款具备口服活性的共价pan-FGFR抑制剂，对FGFR1至FGFR4的IC50值分别为9.9 nM、3.1 nM、16 nM和1.8 nM。该化合物能够在纳摩尔水平有效抑制多种肿瘤细胞的增殖，并在荷瘤小鼠模型中显著地抑制肿瘤生长。
T73179	HDAC-IN-50
	HDAC-IN-50是一种口服活性的有效FGFR和HDAC双重抑制剂，其IC50值针对FGFR1、FGFR2、FGFR3、FGFR4、HDAC1、HDAC2、HDAC6、HDAC8分别为0.18、1.2、0.46、1.4、1.3、1.6、2.6、13 nM。该化合物能诱导(Apoptosis)及使细胞周期在G0/G1期停滞，降低pFGFR1、pERK、pSTAT3的表达，展现出抗肿瘤活性。
T3274	S49076	FGFR; c-Met/HGFR; TAM Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	S49076 是一种新型 MET、AXL/MER 和 FGFR1/2/3 高效抑制剂，IC50<20 nM。
T7611	ODM-203	VEGFR; FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	ODM-203 是 FGFR 和 VEGFR 家族的抑制剂，具有显著的抗肿瘤活性，能够诱导抗肿瘤免疫。
T1886	TAK-632	Raf; FGFR; PDGFR; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; MAPK; Tyrosine Kinase/Adaptors
	TAK632 是一种有效的pan-RAF 抑制剂，对CRAF、BRAFV600E 和BRAFWT 的IC50分别为 1.4、2.4 和 8.3 nM。

化合物

Cat.No: T73146

Cat.No: T64107

Cat.No: T82405

Target: FGFR

Cat.No: T64215

Cat.No: T73145

Cat.No: T82404

Target: FGFR

Cat.No: T8492

Target: Apoptosis, FGFR

Dovitinib lactate hydrate

Cat.No: T6479

Synonym: Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Infigratinib phosphate

Cat.No: T16364

Synonym: NVP-BGJ398 phosphate,BGJ-398 phosphate

Target: FGFR

Cat.No: TQ0228

Synonym: ARQ-087

Target: FGFR

Dovitinib lactate

Cat.No: T7104

Synonym: CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Cat.No: T12401

Synonym: INCB054828

Target: FGFR

Cat.No: T6024

Synonym: FF284,CH5183284,Debio 1347

Target: FGFR

Cat.No: T61304

Target: FGFR

Cat.No: T2361

Synonym: LY 2874455,LY-2874455

Target: VEGFR, FGFR

Cat.No: T3466

Target: EGFR, FGFR

Cat.No: T76877

Synonym: RG-7444,B-701,MFGR-1877S

Target: FGFR

Cat.No: T6028

Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase

Cat.No: T1777

Synonym: BIBF 1120,Intedanib,尼达尼布

Target: VEGFR, FGFR, FLT, PDGFR, Src

Cat.No: T1948

Target: VEGFR, FGFR

Cat.No: T6435

Synonym: 2-[4-[6-氯-2-(4-二甲基氨基苯基)-3H-咪唑并[4,5-B]吡啶-7-基]哌嗪-1-基]-N-(噻唑-2-基)乙酰胺

Target: Aurora Kinase

Cat.No: T6836

Target: FGFR

Cat.No: T1975

Synonym: BGJ-398,NVP-BGJ398

Target: Apoptosis, FGFR

Cat.No: T5122

Synonym: RPT835

Target: Apoptosis, FGFR

Cat.No: TQ0015

Target: c-Fms, FGFR, CSF-1R

Nintedanib esylate

Cat.No: T5001

Synonym: Intedanib,乙磺酸尼达尼布,BIBF 1120 (esylate),尼达尼布乙磺酸盐,Nintedanib Ethanesulfonate Salt,BIBF 1120

Target: VEGFR, FGFR, PDGFR

Cat.No: T2609

Synonym: AB1010,马赛替尼

Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck

Cat.No: T37426

Synonym: FGFR irreversible inhibitor-1

Target: FGFR

Cat.No: T2347

Target: FGFR

Cat.No: T64125

SNIPER(TACC3)-11

Cat.No: T74462

Cat.No: T5473

Synonym: ASP-5878

Target: FGFR

Cat.No: T76367

Cat.No: T77145

E7090 succinate

Cat.No: T72749

VSPPLTLGQLLS TFA

Cat.No: T76368

Derazantinib Racemate

Cat.No: T10997

Synonym: ARQ-087 Racemate

Target: Others

Cat.No: T76277

Cat.No: T3726

Synonym: 厄达替尼,JNJ-42756493

Target: Apoptosis, FGFR

Cat.No: T62652

Cat.No: T62682

Cat.No: T73316

Cat.No: T39001

Cat.No: T62653

Cat.No: T70276

Cat.No: T79257

Target: FGFR

Cat.No: T73179

Cat.No: T3274

Target: FGFR, c-Met/HGFR, TAM Receptor

Cat.No: T7611

Target: VEGFR, FGFR

Cat.No: T1886

Target: Raf, FGFR, PDGFR, Aurora Kinase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) CEK2,HSFGFR3EX,fibroblast growth factor re...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPK-00387	FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated HSFGFR3EX,FGF R3,EC 2.7.10,CD...	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPK-00384	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) CD333,EC 2.7.10,JTK4,FGFR	Human	HEK293 Cells
	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
TMPK-00391	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated HSFGFR3EX,FGFR3,FGF R	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPY-04165	FGFR3 Protein, Human, Recombinant (His) JTK4,CEK2,fibroblast growth factor receptor 3,HS	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPK-00686	FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) CEK,CD333,HSFGFR3	Mouse	HEK293 Cells
	FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9.
TMPK-00385	FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) FGFR3,EC 2.7.10,FGFR3 β ...	Human	HEK293 Cells
	FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P22607-1.
TMPK-00389	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) FGFR3,FGFR3 β (IIIb),CD<...	Human	HEK293 Cells
	FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa and the accession number is P22607-2.
TMPK-00386	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated ACH,CD333,EC 2.7.10,FGFR...	Human	HEK293 Cells
	FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
TMPK-00390	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated FGFR3,JTK4,ACH,FGF R3,FGFR	Human	HEK293 Cells
	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
TMPK-00388	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) HSFGFR3EX,FGF R3,ACH,CD3...	Human	HEK293 Cells
	FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
TMPY-00389	FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) ACH,HSFGFR3EX,fibroblast growth factor rec...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is P22607-2.
TMPY-04200	FGFR3 Protein, Human, Recombinant (hFc) CD333,HSFGFR3EX...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is P22607-1.
TMPY-01208	FGFR3 Protein, Mouse, Recombinant (His) fibroblast growth factor receptor 3,Mfr3,H...	Mouse	HEK293 Cells
	FGFR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is Q7TSI8.
TMPY-00257	FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His) fibroblast growth factor receptor 3	Cynomolgus,Rhesus	HEK293 Cells
	FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is XP_005554344.1.
TMPY-02853	FGFR3 Protein, Cynomolgus, Recombinant (hFc) fibroblast growth factor receptor 3	Cynomolgus	HEK293 Cells
	FGFR3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is F7FZR9.
TMPY-00973	FGFR3 Protein, Mouse, Recombinant (His & hFc) FR3,Fgfr-3,Flg-2,CD3...	Mouse	HEK293 Cells
	FGFR3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q7TSI8.
TMPY-03104	FGF-17 Protein, Human, Recombinant fibroblast growth factor 17,HH20,FGF-13,FGF-17	Human	E. coli
	FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol...
TMPY-02907	FGF-19 Protein, Human, Recombinant fibroblast growth factor 19,FGF19	Human	E. coli
	FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPH-00369	FGF-2 Protein, Chicken, Recombinant (His & Myc)	Chicken	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.8 kDa and the accession number is P48800.
TMPH-00368	FGF-2 Protein, Chicken, Recombinant (His)	Chicken	P. pastoris (Yeast)
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P48800.
TMPH-03203	FGFb Protein, Rabbit, Recombinant (His & SUMO)	Rabbit	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp...
TMPY-02240	STAT1 Protein, Human, Recombinant (His & GST) IMD31A,IMD31B,IMD31C,STAT91,CANDF...	Human	Baculovirus Insect Cells
	STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands, including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. It is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),...

重组蛋白

FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

Cat.No: TMPY-00341

Species: Human

Expression System: HEK293 Cells

FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00387

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00384

Species: Human

Expression System: HEK293 Cells

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00391

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04165

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00686

Species: Mouse

Expression System: HEK293 Cells

FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00385

Species: Human

Expression System: HEK293 Cells

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00389

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00386

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00390

Species: Human

Expression System: HEK293 Cells

FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00388

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)

Cat.No: TMPY-00389

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04200

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01208

Species: Mouse

Expression System: HEK293 Cells

FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-00257

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

FGFR3 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-02853

Species: Cynomolgus

Expression System: HEK293 Cells

FGFR3 Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-00973

Species: Mouse

Expression System: HEK293 Cells

FGF-17 Protein, Human, Recombinant

Cat.No: TMPY-03104

Species: Human

Expression System: E. coli

FGF-19 Protein, Human, Recombinant

Cat.No: TMPY-02907

Species: Human

Expression System: E. coli

FGF-2 Protein, Chicken, Recombinant (His & Myc)

Cat.No: TMPH-00369

Species: Chicken

Expression System: E. coli

FGF-2 Protein, Chicken, Recombinant (His)

Cat.No: TMPH-00368

Species: Chicken

Expression System: P. pastoris (Yeast)

FGFb Protein, Rabbit, Recombinant (His & SUMO)

Cat.No: TMPH-03203

Species: Rabbit

Expression System: E. coli

STAT1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02240

Species: Human

Expression System: Baculovirus Insect Cells

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