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Search Results for " f 1 "

169

抑制剂 & 化合物

50

天然产物

3

同位素

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Cat. No.	Product Name	Target	Signaling Pathways
T11254	F-1	ROS; ALK; ROS Kinase	Angiogenesis; Immunology/Inflammation; Tyrosine Kinase/Adaptors
	F-1 是 ALK 和 ROS1 的双重抑制剂，抑制 ALK 的磷酸化及下游通路，可作用于对 ALKWT (IC50:2.1 nM)，ROS1WT (IC50:2.3 nM)，ALKL1196M (IC50:1.3 nM) 和 ALKG1202R (IC50:3.9 nM)。
T19840	GSK-F1 PI4KA inhibitor-F1	PI4K	PI3K/Akt/mTOR signaling
	GSK-F1 (PI4KA inhibitor-F1) 是一种新型强效 PI4KA 抑制剂。
T67837	(3S)-GSK-F1 PI4KA inhibitor-F1	PI4K	PI3K/Akt/mTOR signaling
	(3S)-GSK-F1是一种选择性PI4KIIIα抑制剂，pIC50=8.3。
T62204	NR2F6 modulator-1	Others	Others
	NR2F6 modulator-1 是一种核受体亚族 2，F 组第 6 号成员 (NR2F6) 的有效调节剂。NR2F6 modulator-1 能够用于研究免疫调节和肿瘤干细胞活性的调节。
T30665	C.I. Direct Red 1, disodium salt Japanol Fast Red 1,COLUMBIA FAST RED F,Chrome Fast Red F,Neonyl Red 2B,Enianil Fast Red F
	C.I. Direct Red 1, disodium salt is a dye.
T72501	CYP4A11/CYP4F2-IN-1	P450	Metabolism
	CYP4A11/CYP4F2-IN-1 是一种高效的小分子细胞色素 P450 (CYP) 4A11 和 CYP4F2 抑制剂，对P450 (CYP) 4A11 的 IC50 值为 19 nM，对 CYP4F2 的 IC50 值为 17 nM。CYP4A11/CYP4F2-IN-1 可用于研究肾脏疾病和心脑血管疾病。
T34652	SK&F 39728-A SK&F39728-A,SK&F 1-39728,SK&F-39728-A,Skf 39728-A	Others	Others
	SK&F 39728-A is a bioactive chemical.
T19688	Lodenosine FddA,3'-dideoxyarabinosyladenine,Fddl,2'-F-dd-ara-A,2'-Fluoro-2',DDG-1	Others	Others
	Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV.
T37919	Prostaglandin F1α PGF1α,Prostaglandin F1α	Others	Others
	Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. [1] PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. [2] It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro. [3]
TP2476	Tnrnflrfamide Thr-asn-arg-asn-phe-leu-arg-phe-NH2,Peptide F(1), lobster,F1 Peptide, lobster,Lobster peptide F1
	Tnrnflrfamide is a SCP (small cardioactive peptide)-like peptide found in lobster neurons; exhibits FMRFamide-like immunoreactivity.
T19618	(R)-(-)-JQ1 Enantiomer (R)-(-)2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂环庚烷-6-基)乙酸叔丁酯	Epigenetic Reader Domain	Chromatin/Epigenetic
	(R)-(-)-JQ1 Enantiomer 是 (+)-JQ1 的立体异构体。 (+)-JQ1 是一种 BET 溴结构域抑制剂，对BRD4(1/2)的IC50 为 77 和 33 nM。
T39606	CE3F4 analog 1	Others	Others
	CE3F4 analog 1 is an analogue of CE3F4.
T36771	11-deoxy Prostaglandin F1α 11-deoxy Prostaglandin F1α	Others	Others
	11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs.
T125155	Schidigerasaponin F1	Others	Others
	Schidigerasaponin F1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125155，CAS号为 266998-42-9。
T84530	Prostaglandin F1β 9β-PGF1α	Others	Others
	PGF1β, a biochemical compound, functions as a pivotal mediator in inflammatory processes and plays an integral role in uterine contractions. It exhibits significant regulatory effects on platelet aggregation and vasodilation, demonstrating its critical importance in cardiovascular health. Additionally, PGF1β contributes to the regulation of kidney function and electrolyte balance, illustrating its widespread impact across various physiological systems.
T79199	F-CRI1	STING	Immunology/Inflammation
	F-CRI1为高效STING激动剂，Kd值达40.62 nM。该化合物通过18F标记成为放射性探针，适用于肿瘤微环境中STING可视化的研究。
T83670	F1 TFA Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide
	F1是一种抗炎肽，由HIV-1 Tat蛋白质转导域与对应于抑制因子NF-κB激酶-相互作用肽（IKIP）46-60残基的15氨基酸肽链接而成。在5 µM浓度下，F1抑制了小鼠腹腔巨噬细胞中LPS诱导的IκB激酶α（IKKα）和IKKβ的磷酸化以及NF-κB（p65）的核内转移。在体内，F1（5 mg/kg）降低了LPS诱导的脓毒症小鼠模型中IL-6、TNF-α和IL-1β的血清水平，并增加了生存率。
T36163	8-iso Prostaglandin F1β 8-iso Prostaglandin F1β	Others	Others
	8-iso PGF1β is a potential autoxidation product of DGLA. There are no published reports on its isolation from any biological source or on its biological activity.
T65682	11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride	Others	Others
	11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65682，CAS号为 111974-74-4。
T126048	Coreanoside F1	Others	Others
	Coreanoside F1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126048，CAS号为 132282-69-0。
T36772	11-deoxy Prostaglandin F1β 11-deoxy Prostaglandin F1β	Others	Others
	11-deoxy PGF1β is a synthetic analog of PGF1β. In contrast to PGF2α and PGF1α, 11-deoxy PGF1β exhibits vasodepressor and bronchodilator activities in guinea pigs at a dose of 500 μg/kg.
T37990	15-keto Prostaglandin F1α 15-keto Prostaglandin F1α	Others	Others
	15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.
T125598	F 11334A1	Others	Others

T36162	8-iso Prostaglandin F1α 8-iso Prostaglandin F1α	Others	Others
	8-iso PGF1α is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy congener at 5-10 μg/ml of seminal plasma.
T72776	NR2F1 agonist 1	Others	Others
	NR2F1 agonist 1 是一种核受体 NR2F1激动剂，可特异性激活恶性细胞的休眠程序。NR2F1 agonist 1 上调 NR2F1 和调节休眠的下游靶基因。NR2F1 agonist 1 通过 NR2F1 激活在头颈部鳞状细胞癌 (HNSCC) 中诱导神经嵴样生长抑制。NR2F1 agonist 1 在小鼠原发肿瘤模型中抑制肿瘤生长。
T69659	MC-1-F2	Others	Others
	MC-1-F2 is the first inhibitor of forkhead Box Protein C2 (FOXC2).
T70074	SB1-F-21	Others	Others
	SB1-F-21 is an UCHL1 inhibitor.
T65991	(S)-4-Phenoxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine	Others	Others
	(S)-4-Phenoxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T65991。
T64437	5-(11bR)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine	Others	Others
	5-(11bR)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64437。
T69947	SB1-F-78	Others	Others
	SB1-F-78 is an USP30 inhibitor.
T37327	Prostaglandin F2α 1,15-lactone Prostaglandin F2α 1,15-lactone	Others	Others
	PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
T65992	(R)-4-Phenoxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine	Others	Others
	(R)-4-Phenoxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T65992。
T36148	13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α	Others	Others
	13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach. The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in vivo production of PGF1α.
T84573	1a,1b-dihomo Prostaglandin F2α 1a,1b-dihomo PGF2α	Others	Others
	1a,1b-Dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α), a hypothetical product of adrenic acid in the COX pathway, is predominantly synthesized in the renal medulla, reflecting the selective distribution of adrenic acid in this region.
T36724	6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro Prostaglandin F1α	Others	Others
	6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. It was shown to enhance intracellular cAMP and cholesterol catabolism in bovine arterial smooth muscle cells.
T84529	Δ17-6-keto Prostaglandin F1α ω-3 6-keto PGF2α	Others	Others
	Δ17-6-keto Prostaglandin F1α (Δ17-6-keto PGF1α), a cyclooxygenase (COX) metabolite produced from eicosapentaenoic acid (EPA) in a variety of tissues including seminal vesicles, lungs, polymorphonuclear leukocytes, and ocular tissues, alongside other 3-series COX products from EPA such as PGF3α, PGE3, and thromboxane B3, is potentially linked to a lower occurrence of glaucoma in individuals consuming a marine-rich (EPA-rich) diet.
T84636	Prostaglandin F2α-1-glyceryl ester PGF2α-1-glyceryl ester	Others	Others
	Prostaglandin F2α-1-glyceryl ester 由15-羟基前列腺素脱氢酶（15-HPGDH）氧化。
T84574	Prostaglandin F2α 1,9-lactone PGF2α 1,9-lactone	Others	Others
	Prostaglandin F2α (PGF2α) 1,9-lactone, a lipid-soluble internal ester of PGF2α, demonstrates resistance to hydrolysis by human plasma esterases, maintaining its structure even after 20 hours of incubation under physiological conditions. Unlike PGF2α, this compound exhibits minimal antifertility and vasoactivity.
T83662	2,3-dinor-8-iso Prostaglandin F1α 2,3-dinor-8-iso PGF1α,2,3-dinor-iPF1α-III,2,3-dinor-5,6-dihydro-15-F2t-Isoprostane,2,3-dinor-5,6-dihydro-15-F2t-IsoP	Others	Others
	2,3-dinor-8-iso Prostaglandin F1α（2,3-dinor-8-iso PGF1α）是一种异前列腺素和花生四烯酸的活性代谢物，也是血小板聚集抑制剂8-iso PGF2α的产物。它通过花生四烯酸的非酶促自由基过氧化作用形成。2,3-dinor-8-iso PGF1α在孤立的猪视网膜和大脑微血管中引起血管收缩（EC50s分别为12.8和18.5 nM），但在31 µM的浓度下使用时不会引起孤立的大鼠主动脉环的收缩。在1 µM的浓度下使用时，它能增加孤立的猪大脑切片中的血栓素B2（TXB2）水平，这一效应可以通过血栓素A合成酶抑制剂CGS 12970、电压门控钙通道抑制剂SKF 96365或烟碱型乙酰胆碱受体（nAChR）拮抗剂α-conotoxin来逆转。
T67397	(11aS)-1,11-Bis(diphenylphosphino)dibenzo[d,f][1,3]dioxepine	Others	Others
	(11aS)-1,11-Bis(diphenylphosphino)dibenzo[d,f][1,3]dioxepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67397。
T78341	Human IgG1 (F405L) kappa, Isotype Control
	HumanIgG1(F405L) kappa, Isotype Control为人-鼠嵌合型单克隆抗体，作为HumanIgG1(F405L)κ抗体的同型对照使用。
T67396	(11aR)-1,11-Bis(diphenylphosphino)dibenzo[d,f][1,3]dioxepine	Others	Others
	(11aR)-1,11-Bis(diphenylphosphino)dibenzo[d,f][1,3]dioxepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67396。
T65432	10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine	Others	Others
	10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65432，CAS号为 3159-07-7。
T65416	Pyrrolo[2,1-f][1,2,4]triazin-4-amine	Others	Others
	Pyrrolo[2,1-f][1,2,4]triazin-4-amine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65416，CAS号为 159326-68-8。
T78270	Anti-Mouse PD-L1 Antibody (10F.9G2)	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Anti-MousePD-L1Antibody为针对小鼠PD-L1的IgG2b类免疫抗体，起源宿主为大鼠(Rat)。
T64639	(11AS)-5-(4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine	Others	Others
	(11AS)-5-(4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64639。
T64496	7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine	Others	Others
	7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64496，CAS号为 1770840-43-1。
T66114	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine	Others	Others
	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66114，CAS号为 937046-98-5。
T64513	(11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine	Others	Others
	(11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64513。
T64587	p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R	Others	Others
	p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64587。

化合物

Cat.No: T11254

Target: ROS, ALK, ROS Kinase

Cat.No: T19840

Synonym: PI4KA inhibitor-F1

Target: PI4K

Cat.No: T67837

Synonym: PI4KA inhibitor-F1

Target: PI4K

NR2F6 modulator-1

Cat.No: T62204

Target: Others

C.I. Direct Red 1, disodium salt

Cat.No: T30665

Synonym: Japanol Fast Red 1,COLUMBIA FAST RED F,Chrome Fast Red F,Neonyl Red 2B,Enianil Fast Red F

CYP4A11/CYP4F2-IN-1

Cat.No: T72501

Target: P450

Cat.No: T34652

Synonym: SK&F39728-A,SK&F 1-39728,SK&F-39728-A,Skf 39728-A

Target: Others

Cat.No: T19688

Synonym: FddA,3'-dideoxyarabinosyladenine,Fddl,2'-F-dd-ara-A,2'-Fluoro-2',DDG-1

Target: Others

Prostaglandin F1α

Cat.No: T37919

Synonym: PGF1α,Prostaglandin F1α

Target: Others

Cat.No: TP2476

Synonym: Thr-asn-arg-asn-phe-leu-arg-phe-NH2,Peptide F(1), lobster,F1 Peptide, lobster,Lobster peptide F1

(R)-(-)-JQ1 Enantiomer

Cat.No: T19618

Synonym: (R)-(-)2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂环庚烷-6-基)乙酸叔丁酯

Target: Epigenetic Reader Domain

Cat.No: T39606

Target: Others

11-deoxy Prostaglandin F1α

Cat.No: T36771

Synonym: 11-deoxy Prostaglandin F1α

Target: Others

Schidigerasaponin F1

Cat.No: T125155

Target: Others

Prostaglandin F1β

Cat.No: T84530

Synonym: 9β-PGF1α

Target: Others

Cat.No: T79199

Target: STING

Cat.No: T83670

Synonym: Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide

8-iso Prostaglandin F1β

Cat.No: T36163

Synonym: 8-iso Prostaglandin F1β

Target: Others

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride

Cat.No: T65682

Target: Others

Cat.No: T126048

Target: Others

11-deoxy Prostaglandin F1β

Cat.No: T36772

Synonym: 11-deoxy Prostaglandin F1β

Target: Others

15-keto Prostaglandin F1α

Cat.No: T37990

Synonym: 15-keto Prostaglandin F1α

Target: Others

Cat.No: T125598

Target: Others

8-iso Prostaglandin F1α

Cat.No: T36162

Synonym: 8-iso Prostaglandin F1α

Target: Others

NR2F1 agonist 1

Cat.No: T72776

Target: Others

Cat.No: T69659

Target: Others

Cat.No: T70074

Target: Others

(S)-4-Phenoxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine

Cat.No: T65991

Target: Others

5-(11bR)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine

Cat.No: T64437

Target: Others

Cat.No: T69947

Target: Others

Prostaglandin F2α 1,15-lactone

Cat.No: T37327

Synonym: Prostaglandin F2α 1,15-lactone

Target: Others

(R)-4-Phenoxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine

Cat.No: T65992

Target: Others

13,14-dihydro-15-keto Prostaglandin F1α

Cat.No: T36148

Synonym: 13,14-dihydro-15-keto Prostaglandin F1α

Target: Others

1a,1b-dihomo Prostaglandin F2α

Cat.No: T84573

Synonym: 1a,1b-dihomo PGF2α

Target: Others

6,15-diketo-13,14-dihydro Prostaglandin F1α

Cat.No: T36724

Synonym: 6,15-diketo-13,14-dihydro Prostaglandin F1α

Target: Others

Δ17-6-keto Prostaglandin F1α

Cat.No: T84529

Synonym: ω-3 6-keto PGF2α

Target: Others

Prostaglandin F2α-1-glyceryl ester

Cat.No: T84636

Synonym: PGF2α-1-glyceryl ester

Target: Others

Prostaglandin F2α 1,9-lactone

Cat.No: T84574

Synonym: PGF2α 1,9-lactone

Target: Others

2,3-dinor-8-iso Prostaglandin F1α

Cat.No: T83662

Synonym: 2,3-dinor-8-iso PGF1α,2,3-dinor-iPF1α-III,2,3-dinor-5,6-dihydro-15-F2t-Isoprostane,2,3-dinor-5,6-dihydro-15-F2t-IsoP

Target: Others

(11aS)-1,11-Bis(diphenylphosphino)dibenzo[d,f][1,3]dioxepine

Cat.No: T67397

Target: Others

Human IgG1 (F405L) kappa, Isotype Control

Cat.No: T78341

(11aR)-1,11-Bis(diphenylphosphino)dibenzo[d,f][1,3]dioxepine

Cat.No: T67396

Target: Others

10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine

Cat.No: T65432

Target: Others

Pyrrolo[2,1-f][1,2,4]triazin-4-amine

Cat.No: T65416

Target: Others

Anti-Mouse PD-L1 Antibody (10F.9G2)

Cat.No: T78270

Target: PD-1/PD-L1

(11AS)-5-(4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine

Cat.No: T64639

Target: Others

7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine

Cat.No: T64496

Target: Others

7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine

Cat.No: T66114

Target: Others

(11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine

Cat.No: T64513

Target: Others

p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R

Cat.No: T64587

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3401	Ginsenoside F1 人参皂苷 F1,20(S)-Ginsenoside F1	P450; Endogenous Metabolite	Metabolism
	Ginsenoside F1 (20(S)-Ginsenoside F1) 是一种 Ginsenoside Rg1 的酶促修饰衍生物，它竞争性抑制CYP3A4，对 CYP2D6 具有较弱的抑制作用。
T5S2139	Epimedin A1 朝藿定A1,Hexandraside F	Others	Others
	Epimedin A1 (Hexandraside F) 是一种黄酮类化合物，从常用中药淫羊藿中提取得到。
T8716	physalin F 酸浆苦味素F,酸浆苦素 F	Apoptosis	Apoptosis
	Physalin F 是一种分泌型甾体，诱导人外周血单个核细胞凋亡，降低人 T 淋巴细胞 1 型病毒感染后的自发增殖和细胞因子的产生，具有强烈抗炎和免疫调节作用。
TN4161	Goshonoside F1
	Goshonoside F1是半糯米品种水稻的脂质代谢产物，可被当作培育优良水稻的一个指标。
TN1942	Momordicoside F1 苦瓜皂苷 F1	Others	Others
	Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines.
TN6864	Prosaikogenin F 前柴胡皂苷F	Others	Others
	Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) 是一种单糖苷，具有溶血和抗癌特性。
T3920	Pseudoginsenoside F11 Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11	Others; Endogenous Metabolite	Metabolism; Others
	Pseudoginsenoside F11 (Ginsenoside A1) 从人参根和叶中分离得到。PF11在一系列心血管和中枢神经系统疾病中具有广泛的保护作用。
TN1989	Niga-ichigoside F1 苦莓苷F1	Others; Nrf2	Immunology/Inflammation; Others
	Niga-ichigoside F1(NI) has anti-inflammatory, gastroprotective ,antinociceptive, and cytotoxic effects.
TN2341	Cucurbitacin Q1 葫芦素F-25-乙酸酯,葫芦素Q1	Others	Others
	Cucurbitacin Q1 是一种天然的四环三萜，来源于Cucumis prophetarum。
TN2119	Pulsatilla saponin H 白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷	Others	Others
	Pulsatilla saponin H 是一种从 Pulsatilla koreana 的根中分离出来的天然产物。
TN7315	1-O-Ethylpiptocarphin F	Others	Others
	1-O-Ethylpiptocarphin F is a natural product and can be used as a standard reference.
TN1080	Kaji-ichigoside F1 蔷薇苷
	Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema model in mice and rats. Kaji-ichigoside F1 exhibits in vivo hepatoprotective effects, it inhibite
T81853	Marstenacisside F1
	Marstenacisside F1（化合物1）为从通关藤(Marsdenia tenacissima)分离的抗炎聚氧孕烷苷，能抑制脂多糖激活的RAW 264.7细胞产生一氧化氮(NO)，属Tenacigenin B衍生物。
TN6859	Saikogenin F (1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-ene-2,10-diol	Others	Others
	Saikogenin F ((1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-ene-2,10-diol) 是一种具有抗癌活性的天然产物。
TMA2270	Alisol F 24-acetate	P-gp	Membrane transporter/Ion channel; Neuroscience
	Alisol F 24-acetate 是一种从 Alisma plantago-aquatica Linn [1] 中分离出来的天然产物。 Alisol F 24 Acetate 通过抑制 P-糖蛋白介导的药物流出来增强 MCF-7/DOX 细胞的化学敏感性和凋亡。
T2S0491	Isoeugenol acetate 乙酸异丁香酚酯,Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol,乙酸异丁香酚酯，乙酰基异丁香酚;2-甲氧基-4-丙烯基苯基乙酸酯	AChE; Antifungal	Microbiology/Virology; Neuroscience
	Isoeugenol acetate (Acetylisoeugenol) 是肉豆蔻，丁香和肉桂的精油成分，对某些代谢酶如乙酰胆碱酯酶，能够抑制α-糖苷酶和 α-淀粉酶。它用于医疗和化妆品工业，具有抗氧化，抗癌，抗菌和抗炎作用。
T5S1054	Wilforgine 雷公藤晋碱,雷公藤精碱	Others	Others
	Wilforgine 是一种具有生物活性的倍半萜烯生物碱，存在于Tripterygium wilfordiiHook. F 中。它能诱导分离出丝状体幼虫肌肉的微结构和超微结构变化，其作用部位被认为是肌肉系统中的钙受体或通道。
T4S0498	Glaucocalyxin A 蓝萼甲素,Wangzaozin B,Leukamenin F	Apoptosis; Akt; Caspase; PI3K	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Glaucocalyxin A (Leukamenin F) 是来自日本黑纹病菌的一种对映型月桂基二萜，具有抗肿瘤作用。它通过调节PI3K/Akt 信号通路抑制 GLI1 的核易位，诱导骨肉瘤凋亡。
T36914	2-Hydroxyanthraquinone	Others	Others
	2-Hydroxyanthraquinone 是一种天然产物，显示出抗肿瘤和免疫抑制活性。
T3S0027	Picropodophyllotoxin AXL 1717,Picropodophyllin,苦鬼臼毒素	IGF-1R	Tyrosine Kinase/Adaptors
	Picropodophyllotoxin (AXL 1717) 是一种环木脂素生物碱，存在于五月树(Podophyllum peltatum) 中，是一种具有潜在抗肿瘤活性的胰岛素样生长因子 1 受体 (IGF1R) 的小分子抑制剂。它特异性抑制 IGF1R 的活性并下调细胞表达，而不干扰其他生长因子受体的活性，例如胰岛素受体、表皮生长因子、血小板衍生生长因子、成纤维细胞生长因子和肥大/干细胞生长因子 (KIT) ）。该药剂在抑制肿瘤细胞增殖和诱导肿瘤细胞凋亡方面显示出有效的活性。 IGF1R 是一种在多种人类癌症中过度表达的受体酪氨酸激酶，在多种癌细胞的生长和存活中起关键作用。
T75654	F-14329	Others	Others
	F-14329 是一种四元酸真菌代谢物。
T80864	Virgaureagenin F
	Virgaureagenin F, 一种从Rhizoma bolbostemmae中提取的皂苷。
T83216	Abiesadine F
	Abiesadine F为从Abies georgei Orr分离出的一种二萜化合物。
T83107	Anhuienside F
	Anhuienside F，一种从Anemone vitifolia Buch.-Ham根部提取的天然化合物。
T82399	Fipsomin
	Fipsomin为从F. nipponica果实中提取的天然化合物。
T82738	Chisocheton compound F
	Chisocheton compound F，一种从Melia toosendan茎皮中分离的天然产物。
TN4411	Lappaol F	CDK; P-gp; JNK	Cell Cycle/Checkpoint; MAPK; Membrane transporter/Ion channel; Neuroscience
	1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. <br/> 2. Lappaol F has potential chemosensitizing activity, it may be candidates for developing novel adju
T81093	Sterebin F
	Sterebin F, 一种甾类化合物，来源于Stevia rebaudiana叶的分离提取，表现出降血糖的活性。
T79992	Sarglaroids F	Caspase	Apoptosis; Proteases/Proteasome
	Sarglaroids F（化合物6）为从草珊瑚根部提取的抗炎剂，影响K+外排并降低Caspase-1(P20)水平以抑制LPS/ATP诱导的IL-1β释放，对RAW264.7细胞无细胞毒性。
TMA0593	Broussoflavonol F	Tyrosinase	Proteases/Proteasome
	Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase. Broussoflavonol F
T83565	(2E)-Leocarpinolide F
	（2E）-Leocarpinolide F（化合物20），为从Sigesbeckia orientalis中提取的香叶鹤型倍半萜。
TN6249	(+)-Isoampelopsin F
	(+)-Isoampelopsin F 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6249，CAS号为 354553-38-1。
T80941	Triptonoterpene Me ether
	Triptonoterpene Me ether（compound 5）为一种从中药雷公藤（Tripterygium wilfordii Hook. f.）分离出的松香烷型二萜类化合物。
T81941	Leocarpinolide F
	Leocarpinolide F，一天然提取自Siegesbeckia orientalis的类倍半萜烯。
TN5988	16,25-Di-O-acetylcucurbitacin F 16,25-O-Diacetyl-cucurbitane F,Cucurbitacin F 16,25-diacetate
	16,25-Di-O-acetylcucurbitacin F 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5988，CAS号为 2062685-10-1。
T83108	Anhuienoside B	Others	Others
	Anhuienoside B为从C. anhuiensis K. F. Wu鲜叶中提取的天然产物，能应对CuCl2诱导的非生物胁迫。
T82338	Ganoapplanoid F
	Ganoapplanoid F，一种三萜类化合物，源自Ganoderma applanatum，具有抑制脂肪细胞脂质积累的功能，适用于肥胖研究领域。
TN4977	Scutebata F	Others	Others
	Scutebata F 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4977，CAS号为 1207181-62-1。
T79937	Mortatarin F	Glucosidase	Metabolism
	Mortatarin F (Compound 1) 是一种具有戊烯基化类黄酮结构的葡萄糖苷酶抑制剂，其IC50值为8.7 μΜ。该化合物可从桑叶中提取，并应用于研究降低血糖效果。
T82067	Inonotusol F
	Inonotusol F, 一种三萜化合物，可在Inonotus obliquus中分离出。该化合物对D-半乳糖胺诱导的WB-F344细胞损伤显示出保肝效应。
T80002	Wulfenioidin F	Virus Protease	Microbiology/Virology
	Wulfenioidin F是从Orthosiphon wulfenioides全草分离的二萜类化合物。该化合物对抗寨卡病毒(ZIKV)活性显著，其半数有效浓度(EC50)为8.07 μM。Wulfenioidin F的抗病毒机制通过抑制ZIKV包膜(E)蛋白的表达，从而干扰病毒复制。
T82459	Epicornuin F
	Epicornuin F，一种源自Epimedium brevicornu叶片的异戊二烯黄酮化合物，展现了对HepG2细胞线的显著细胞毒性，IC50为33.4 μM，适用于癌症研究领域。
T82986	Apigenin triacetate
	Apigenin triacetate, 作为禾谷镰刀菌的代谢产物，其含量可通过壳聚糖处理以实现下调。该化合物系由芹菜素派生。
T83479	1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione
	1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione 是一种从丹参酮 (Salvia miltiorrhiza f. alba) 中提取的化学物质，具有二氢异丹参酮结构，显示出细胞毒性和抗肿瘤的活性。
TMA1012	Ganoderiol F	Androgen Receptor; HIV Protease; Autophagy	Autophagy; Endocrinology/Hormones; Microbiology/Virology; Proteases/Proteasome
	Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS)-induced nitric oxide (NO) production.
T81676	NG-012
	NG-012为一种神经生长因子(NGF)增强剂，来源于Penicillium verruculosum F-4542的培养液。该化合物能在大鼠嗜铬细胞瘤细胞系(PC12)中提升NGF引导的神经突生长效应。
T81531	Pedunculosumoside F
	Pedunculosumoside F，一种从Ophioglossum pedunculosum分离得到的同型黄酮苷，对HepG2 2.2.15细胞表现出细胞毒性，其CC50值为56.7 μM，但缺乏抗HBV活性。然而，其类似物能够抑制HBV感染的HepG2 2.2.15细胞中HBsAg的分泌。
T75540	Ipomoeassin F	Others	Others
	Ipomoeassin F 是一种高效且具有选择性的内质网(ER)蛋白转位抑制剂，它通过作用于ER膜上的Sec61复合物（Sec61α）的成孔亚基来实现其功能。此化合物能特异性抑制SARS-CoV-2蛋白在ER膜上的转位，同时阻碍分泌蛋白和I型跨膜蛋白（TMP）的ER转运，但对III型TMP的转运不产生影响。
T36000	3-Hydroxyterphenyllin	Others	Others
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...
T36954	Nemorosone	Others	Others
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...
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天然产物

Cat.No: T3401

Synonym: 人参皂苷 F1,20(S)-Ginsenoside F1

Target: P450, Endogenous Metabolite

Cat.No: T5S2139

Synonym: 朝藿定A1,Hexandraside F

Target: Others

Cat.No: T8716

Synonym: 酸浆苦味素F,酸浆苦素 F

Target: Apoptosis

Cat.No: TN4161

Momordicoside F1

Cat.No: TN1942

Synonym: 苦瓜皂苷 F1

Target: Others

Prosaikogenin F

Cat.No: TN6864

Synonym: 前柴胡皂苷F

Target: Others

Pseudoginsenoside F11

Cat.No: T3920

Synonym: Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11

Target: Others, Endogenous Metabolite

Niga-ichigoside F1

Cat.No: TN1989

Synonym: 苦莓苷F1

Target: Others, Nrf2

Cucurbitacin Q1

Cat.No: TN2341

Synonym: 葫芦素F-25-乙酸酯,葫芦素Q1

Target: Others

Pulsatilla saponin H

Cat.No: TN2119

Synonym: 白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷

Target: Others

1-O-Ethylpiptocarphin F

Cat.No: TN7315

Target: Others

Kaji-ichigoside F1

Cat.No: TN1080

Synonym: 蔷薇苷

Marstenacisside F1

Cat.No: T81853

Cat.No: TN6859

Synonym: (1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-ene-2,10-diol

Target: Others

Alisol F 24-acetate

Cat.No: TMA2270

Target: P-gp

Isoeugenol acetate

Cat.No: T2S0491

Synonym: 乙酸异丁香酚酯,Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol,乙酸异丁香酚酯，乙酰基异丁香酚;2-甲氧基-4-丙烯基苯基乙酸酯

Target: AChE, Antifungal

Cat.No: T5S1054

Synonym: 雷公藤晋碱,雷公藤精碱

Target: Others

Glaucocalyxin A

Cat.No: T4S0498

Synonym: 蓝萼甲素,Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

2-Hydroxyanthraquinone

Cat.No: T36914

Target: Others

Picropodophyllotoxin

Cat.No: T3S0027

Synonym: AXL 1717,Picropodophyllin,苦鬼臼毒素

Target: IGF-1R

Cat.No: T75654

Target: Others

Virgaureagenin F

Cat.No: T80864

Cat.No: T83216

Cat.No: T83107

Cat.No: T82399

Chisocheton compound F

Cat.No: T82738

Cat.No: TN4411

Target: CDK, P-gp, JNK

Cat.No: T81093

Cat.No: T79992

Target: Caspase

Broussoflavonol F

Cat.No: TMA0593

Target: Tyrosinase

(2E)-Leocarpinolide F

Cat.No: T83565

(+)-Isoampelopsin F

Cat.No: TN6249

Triptonoterpene Me ether

Cat.No: T80941

Leocarpinolide F

Cat.No: T81941

16,25-Di-O-acetylcucurbitacin F

Cat.No: TN5988

Synonym: 16,25-O-Diacetyl-cucurbitane F,Cucurbitacin F 16,25-diacetate

Cat.No: T83108

Target: Others

Ganoapplanoid F

Cat.No: T82338

Cat.No: TN4977

Target: Others

Cat.No: T79937

Target: Glucosidase

Cat.No: T82067

Cat.No: T80002

Target: Virus Protease

Cat.No: T82459

Apigenin triacetate

Cat.No: T82986

1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione

Cat.No: T83479

Cat.No: TMA1012

Target: Androgen Receptor, HIV Protease, Autophagy

Cat.No: T81676

Pedunculosumoside F

Cat.No: T81531

Cat.No: T75540

Target: Others

3-Hydroxyterphenyllin

Cat.No: T36000

Target: Others

Cat.No: T36954

Target: Others

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Cat. No.	Product Name	Target	Signaling Pathways
T35698	Octanoic Acid-13C
	Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d...
T35515	3-Acetyldeoxy Nivalenol-13C17 3-Acetyldeoxy Nivalenol-13C17
	3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50= 70 mg/kg) in mice.2 1.Jiao, F., Kawakami, A., and Nakajima, T.Effects of different carbon sources on trichothecene production and Tri gene expression by Fusarium grami...
T35775	HT-2 Toxin-13C22 HT-2 Toxin-13C22
	HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...

同位素

Octanoic Acid-13C

Cat.No: T35698

3-Acetyldeoxy Nivalenol-13C17

Cat.No: T35515

Synonym: 3-Acetyldeoxy Nivalenol-13C17

HT-2 Toxin-13C22

Cat.No: T35775

Synonym: HT-2 Toxin-13C22

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