130
36
40
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22373 |
ADA
ADA buffer,N-(2-Acetamido)-2-Iminodiacetic acid,N-(2-乙酰氨基)-亚氨基二醋酸 |
Others | Others |
ADA (N-(2-Acetamido)-2-Iminodiacetic acid) 是一种生物缓冲液,可用作螯合剂。 | |||
T69727 | ADA-07 | ||
ADA-07 is a TOPK inhibitor which interacts with TOPK at the ATP-binding pocket and inhibits its kinase activity, thereby suppressing SUV-induced phosphorylation of ERK1/2, p38, and JNKs, and subsequently inhibiting AP-1 activity. | |||
T69726 |
Oditrasertib
|
||
Oditrasertib 是一种RIPKl 抑制剂,其IC50值低于 100 nM。Oditrasertib 可用于炎症的研究。 | |||
T66562 |
ADA sodium salt
|
||
ADA sodium salt 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66562,CAS号为 7415-22-7。 | |||
T77793 |
Azodicarbonamide
NSC 674447,ADA,HPH-116 |
||
Azodicarbonamide是一个能通过针对nucleocapsid CCHC domains来抑制HIV-1及多种逆转录病毒的核衣壳抑制剂。在标准细胞抗病毒测试中,该化合物能够抑制HIV-1RF引起的CEM-SS细胞病变,其EC50值为38 µM。 | |||
T1398 |
Tadalafil
Cialis,他达那非,IC-351,西力士 |
Apoptosis; PDE | Apoptosis; Metabolism |
Tadalafil (IC-351) 是一种PDE5抑制剂,IC50为 1.8 nM。 | |||
T22022 |
Adaptaquin
|
HIF | Angiogenesis; Chromatin/Epigenetic |
Adaptaquin 是缺氧诱导因子脯氨酰羟化酶(HIF-PH)的抑制剂。 | |||
T4651 |
Vadadustat
N-(5-(3-氯苯基)-3-羟基吡啶-2-羰基)甘氨酸,PG-1016548,AKB-6548 |
HIF/HIF Prolyl-Hydroxylase; HIF | Angiogenesis; Chromatin/Epigenetic; Metabolism |
Vadadustat 是一种可滴定口服的缺氧诱导因子脯氨酰羟化酶 (HIF-PH) 抑制剂,是一种促红细胞生成剂,在动物慢性肾脏疾病模型中,有用于贫血的研究潜力。 | |||
T78216 |
cis-ent-Tadalafil
(6S,12aR)-Tadalafil,Tadalafil, (6S,12aR)-,cis-ent-IC-351 |
Others | Others |
cis-ent-Tadalafil (cis-ent-IC-351) 是一种具有高效和选择性的 PDE5 抑制剂,可降低血压。 | |||
T5636 |
Adavivint
Adavivint (SM04690) |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Adavivint (Adavivint (SM04690)) (SM04690) 是选择性的典型的Wnt 信号通路抑制剂,在 SW480 细胞中,用高通量 TCF/LEF 报告基因实验,测得EC50=19.5 nM。 | |||
T5825 |
Iadademstat dihydrochloride
ORY-1001(trans) |
Histone Demethylase | Chromatin/Epigenetic |
Iadademstat dihydrochloride (ORY-1001(trans)) 是一种不可逆的选择性赖氨酸特异性脱甲基酶 1A(KDM1A/LSD1) 抑制剂,用于治疗急性白血病。 | |||
T27808 |
Lefradafiban
BIBU 104,BIBU104,BIBU-104 |
Others | Others |
Lefradafiban(BIBU-104) 是一种口服血小板糖蛋白 IIb/IIIa 受体拮抗剂,可用于研究心绞痛和急性冠状动脉综合症。 | |||
T5189 |
Omadacycline
PTK 0796,Amadacycline |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂,是四环素类抗生素。它与 30S 核糖体亚基结合,抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染,感染性肺炎和尿路感染。 | |||
T6147 |
Nortadalafil
Demethyl Tadalafil,去甲基他达那非 |
PDE | Metabolism |
Nortadalafil (Demethyl Tadalafil) 是 demethyl Tadalafil,是一种 PDE5 抑制剂。 | |||
T14124 |
ADAMTS-5 Inhibitor
|
Others | Others |
ADAMTS-5 Inhibitor 是 ADAMTS-5 的抑制剂,IC50 为 1.1 µM,可用于关节炎中软骨破坏的研究。 | |||
T2189 |
Sodium orthovanadate
Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate |
ATPase; Phosphatase | Membrane transporter/Ion channel; Metabolism |
Sodium orthovanadate 是一种蛋白酪氨酸磷酸酶,碱性磷酸酶和一些ATP 酶的抑制剂,有可能充当磷酸盐类似物。它具有胰岛素样作用、对心室肌的正性肌力作用和其他代谢作用。 | |||
T4020 |
Cadazolid
ACT-179811,卡达唑利德 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cadazolid (ACT-179811) 是一种新型恶唑烷酮类抗生素,对Clostridium difficile 有活性。 | |||
T14125 |
Adarotene
ST1926 |
Apoptosis | Apoptosis |
Adarotene (ST1926) 是一种细胞凋亡诱导剂,通过产生 DNA 损伤,来阻止人类肿瘤细胞的增殖。 | |||
T38863 |
Luvadaxistat
TAK-831,Luvadaxistat |
||
TAK-831 is a potent and highly selective inhibitor of D-amino acid oxidase (DAAO), offering great potential for utilization in schizophrenia research. | |||
T23631 |
Adatanserin
WY-50324,WY 50324,WAY SEB 324,WY50324 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Adatanserin (WY 50324) 是一种混合型 5-HT1A 受体部分激动剂,也是一种 5-HT2A 和 5-HT2C 受体拮抗剂,具有潜在的神经保护活性,可用于研究焦虑和抑郁症。 | |||
T67787 |
Adafosbuvir PM
AL-335 PM |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Adafosbuvir PM (AL-335 PM) 是一种具有抗病毒活性的化合物。 | |||
T18968 |
Dansylcadaverine
Monodansyl cadaverine,丹酰尸胺 |
Others; Autophagy | Autophagy; Others |
Dansylcadaverine (Monodansyl cadaverine) 是谷氨酰胺转胺酶的高亲和力底物,能阻断受体介导的多种配体的内吞作用。它是一种用于标记自噬空泡的荧光探针。 | |||
T9430 |
Venadaparib
NOV140101,IDX-1197 |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Venadaparib (NOV140101) 是一种选择性和具有口服活性的 PARP 抑制剂,对 PARP1和 PARP2的 IC50分别为 1.4 和 1.0 nM。它可防止 DNA 单链断裂 (SSB) 的修复,可研究实体瘤。 | |||
T9901 |
Adalimumab
|
TNF | Apoptosis |
Adalimumab 是人源的单克隆 IgG1 抗体,靶向肿瘤坏死因子α。 | |||
T0645 |
N-(1-Adamantyl)acetamide
|
Others | Others |
N-(1-Adamantyl)acetamide 用作合成amantadine hydrochloride 的中间体。 | |||
T20013 |
Adamantanine
NSC 145160,NSC145160,NSC-145160,2-氨基金刚烷-2-甲酸 |
Others | Others |
Adamantanine (NSC-145160) 是一种氨基酸转运抑制剂。 | |||
T5659 |
2-Adamantanone
|
Others | Others |
2-Adamantanone 是一种生物活性化学物质。 | |||
T7542 |
Amino Tadalafil
氨基他达那非,氨基他达拉非 |
PDE | Metabolism |
Amino Tadalafil 是一种 Tadalafil 的类似物,是一种磷酸二酯酶 5 抑制剂,可用于多种疾病,如勃起功能障碍,肺动脉高压和下尿路功能障碍。 | |||
T29645 |
Adatanserin hydrochloride
WY50324 hydrochloride |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Adatanserin hydrochloride (WY50324 hydrochloride) 是一种新型 5-HT(1A)/5-HT(2) 受体配体,具有潜在的神经保护作用,抑制内源性氨基酸缺血性外排,可用于研究抑郁症和焦虑症。 | |||
T22553 |
Adaphostin
1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate,NSC 680410 |
Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Adaphostin (NSC-680410) 是 AG957 金刚烷酯,是一种 p210bcr/abl 抑制剂,可诱导 T 淋巴细胞白血病细胞系凋亡。它增加了 CLL B 细胞内活性氧的水平,对慢性和急性髓系白血病细胞具有显著的选择性活性。 | |||
T32039 |
HADA Hydrochloride
HCC-Amino-D-alanine hydrochloride,HADA HCl |
Autophagy | Autophagy |
HADA Hydrochloride (HCC-Amino-D-alanine hydrochloride) 是一种具有蓝色荧光的D 氨基酸 (λem~450 nm)。FDAAs 在肽聚糖 (PG) 合成位点有效地与多种细菌的 PGs 结合。HADA Hydrochloride 而用于在最小干扰下特异性和共价探测细菌的生长。 | |||
T7503 |
Upadacitinib
乌帕替尼,ABT-494 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Upadacitinib (ABT-494) 是高效选择性的,具有口服活性的 JAK1抑制剂,IC50为43 nM,可用于多种自身免疫性疾病的研究。它对 JAK1 的选择性约为 JAK2 的 74 倍。 | |||
T8369 |
Adagrasib
MRTX849 |
Ras | GPCR/G Protein; MAPK |
Adagrasib (MRTX849) 是一种 KRAS G12C 共价抑制剂,具有口服活性和选择性。Adagrasib 与 KRAS G12C 非活性构象的 GDP 状态结合,抑制 KRAS 及其下游信号的传导。Adagrasib 对 KRAS G12C 突变肿瘤具有抑制活性。 | |||
T77018 |
Garadacimab
CSL312 |
Factor Xa | Metabolism |
Garadacimab (CSL312) 是有效的全人 IgG4 单克隆抗体,针对活化因子 XII (FXIIa)。Garadacimab 可用于研究遗传性血管性水肿。 。 | |||
T77505 |
cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride
Quaternium-15 cis-form |
||
cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) 是一种抗菌剂,用于化妆品中作为化妆品防腐剂和抗静电剂。cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride 是一种口服致畸剂,但不是皮肤致畸剂,在大鼠中剂量超过了化妆品的预期累积暴露量。 | |||
T2077 |
Adavosertib
AZD1775,MK-1775,Adavosertib (MK-1775) |
Wee1 | Cell Cycle/Checkpoint |
Adavosertib (MK-1775) 是一种Wee1抑制剂,IC50值为 5.2 nM。它阻碍了 G2 DNA 损伤检查点。 | |||
T8502 |
N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide
|
Influenza Virus | Microbiology/Virology |
N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide 通过与表面糖蛋白结合抑制埃博拉病毒进入宿主细胞,该化合物抑制埃博拉病毒,EC50 为 3.9 μM。 | |||
T1093 |
Adapalene
CD271,阿达帕林 |
Apoptosis; Retinoid Receptor; Autophagy | Apoptosis; Autophagy; Metabolism |
Adapalene (CD271) 是一种合成类视黄醇,局部应用于痤疮。它以非竞争性方式抑制 GOT1的酶活性,具有抗肿瘤活性。它是一种 RAR 激动剂,对 RARβ、RARγ、RARα的AC50值分别为 2.3 nM、9.3 nM 和 22 nM。 | |||
T64479 | (2S,2'S)-1,1'-(2,2'-((3-Hydroxyadamantan-1-yl)azanediyl)bis(acetyl))bis(pyrrolidine-2-carbonitrile) | ||
(2S,2'S)-1,1'-(2,2'-((3-Hydroxyadamantan-1-yl)azanediyl)bis(acetyl))bis(pyrrolidine-2-carbonitrile) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64479。 | |||
T64506 | (1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride dihydrate | ||
(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride dihydrate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64506。 | |||
T23630 | Adapiprazine | ||
Adapiprazine is prochlorperazine that works as an anesthetic drug. | |||
T65005 | Di(adamantan-1-yl)(benzyl)phosphine | ||
Di(adamantan-1-yl)(benzyl)phosphine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65005。 | |||
T75026 | PROTAC TYK2 degradation agent1 | PROTACs | PROTAC |
PROTACTYK2 degradation agent1为亚型选择性TYK2降解剂,表现出杰出的TYK2降解活性,其DC50为14 nM,适用于自身免疫性疾病研究。 | |||
T29295 |
1-Adamantylaspartate
beta-1-Adamantylaspartic acid |
||
1-Adamantylaspartate can be used as a protecting group for protein synthesis. | |||
T72868 | ADAMTS-5-IN-2 | ||
ADAMTS-5-IN-2 是一种有效的ADAMTS-5抑制剂,IC50值为 0.71 µM。ADAMTS-5-IN-2 具有改善骨关节炎的研究潜力。 | |||
T80048 |
Mca-YVADAP-Lys(Dnp)-OH TFA
|
||
Mca-YVADAP-Lys(Dnp)-OH TFA为Caspase-1及血管紧张素转换酶2(ACE2)特异性的荧光底物。 | |||
TD0018 |
Sulfo-Cy7 cadaverine
Cy7,尸胺 |
||
Sulfo-Cyanine7 is an improved analog of Cy7 fluorophore with quantum yield improved by 21%, and higher photostability. This fluorescent dye is especially useful for NIR imaging. | |||
T67239 |
Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II)
|
||
Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67239,CAS号为 909389-99-7。 | |||
T29642 |
Adamantane, 2-chloro-2-nitroso-
|
||
Adamantane, 2-chloro-2-nitroso- is a bioactive chemical. | |||
T20753 |
Omadacycline tosylate
|
||
Omadacycline tosylate is a new tetracycline. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7034 |
1-IODOADAMANTANE
1-Adamantyl Iodide,1-碘金刚烷,Adamantyl iodide |
Others | Others |
1-IODOADAMANTANE (1-Adamantyl Iodide) 用于与烯烃的自由基羰基化反应。 | |||
TN1130 |
Yadanziolide A
鸦胆子素 H,鸦胆子内酯A |
Antiviral | Immunology/Inflammation |
Yadanziolide A 来源于 Brucea javanica 干燥的种子。它具有强的抗病毒作用,能够抗烟草花叶病毒(IC50:5.5 μM)。它具有抗肿瘤活性。 | |||
T5704 |
Entadamide-A-β-D-glucopyranoside
(E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-,榼藤子酰胺A-Β-D-吡喃葡萄糖苷,榼藤子酰胺A-β-D-吡喃葡萄糖 |
Others | Others |
Entadamide-A-β-D-glucopyranoside ((E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-) 是一种菜豆虫种子的主要成分,具有抗补体作用。 | |||
T5658 |
Adamantane
|
Others | Others |
Adamantane 是许多化合物的结构骨架,也是有机多面体化合物的物理化学和生物学特性,在制药工业中有实际应用。 | |||
TWO2771 |
2-Adamantanol
2-金刚烷醇,Adamantan-2-Ol,2-Hydroxyadamantane |
Others | Others |
2-Adamantanol (2-Hydroxyadamantane) 用于合成抗过敏药物Mizolastine。 | |||
TN3235 | 7-Hydroxycadalene | 5-HT Receptor | GPCR/G Protein; Neuroscience |
7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM. | |||
T75531 | Ladanetin-6-O-β-D-glucopyranoside | ||
Ladanetin-6-O-β-D-glucopyranoside, 一种活性类黄酮, 具备抗氧化功能,并可应用于心脏保护研究。 | |||
TN6113 |
3β-Isodihydrocadambine 4-oxide
|
||
3β-Isodihydrocadambine 4-oxide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6113,CAS号为 1092371-18-0。 | |||
T82463 |
Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside
|
||
Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside (MFLNH I) (compound 5) 是一种从泰国药用植物 Entada rheedei 的种子仁中提取的化合物,具有抑制胃痛的功效。 | |||
TN5270 |
Yadanzioside P
|
Others | Others |
Yadanzioside P has antileukemic and antitumor activities. | |||
TN2317 |
Yadanziolide B
|
Others | Others |
Yadanziolide B exhibits cytotoxic activities with IC50 values of 3.00-5.81 μM. | |||
TN6107 |
3β-Isodihydrocadambine
|
Antioxidant; Parasite | Microbiology/Virology; oxidation-reduction |
3β-Isodihydrocadambine 是卡丹宾衍生物,可从Neolamarckia cadamba 树皮和叶子中提取。3β-Isodihydrocadambine 具有抗疟、抗增殖、抗氧化、抗癌和抗炎活性。 | |||
T16381 |
Okadaic acid
|
Others | Others |
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted from black sponges of the genus Halic | |||
TN4404 |
Ladanein
|
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities against K562, K562R (imatinib-resistant), and 697 human leukemia cell lines. | |||
TN2319 |
Yadanzioside A
鸦胆子苷A,鸦胆子内脂A |
Others | Others |
Yadanzioside A has antileukemic activity. | |||
TN5267 |
Yadanzioside I
|
Antifection | Microbiology/Virology |
Yadanzioside I shows strong antiviral activity. | |||
TN5266 |
Yadanzioside F
|
Others | Others |
Yadanzioside F has antileukemic activity. | |||
TN5269 |
Yadanzioside M
|
Others | Others |
Yadanzioside M has antitumor activity. | |||
TN2321 |
Yadanzioside L
|
Antifection | Microbiology/Virology |
Yadanzioside L shows strong antiviral activity. | |||
TN5265 | Yadanzioside C | Others | Others |
Yadanzioside C has antileukemic activity. | |||
TN3749 |
Dadahol A
|
Others | Others |
Dadahol A 是一种天然产物,存在于桑枝。 | |||
T35235 |
Yadanzioside E
|
||
Yadanzioside E is a biochemical. | |||
TN2320 |
Yadanzioside G
|
Others | Others |
Yadanzioside G has antileukemic activity. | |||
TN5268 |
Yadanzioside K
|
Others | Others |
Yadanzioside K is a natural product from Brucea javanica. | |||
TN2990 |
3alpha-dihydrocadambine
|
Others | Others |
3alpha-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats. | |||
T81956 |
Ladanetin-6-O-β-(6′′-O-acetyl)glucoside
|
||
Ladanetin-6-O-β-(6′′-O-acetyl)glucoside 是一种从甘青青兰 (Dracocephalum tanguticum) 全株中提取的黄酮化合物,具备抗氧化特性。该化合物能够保护H9c2心肌细胞免受Doxorubicin(DOX)引起的细胞毒性。 | |||
T82326 |
Genkwadaphnin
|
||
Genkwadaphnin是一种瑞香烷二萜,能够靶向内输蛋白importin-β1,减少CRPC核心驱动因子在细胞核内的积累,并关闭其下游致癌信号通路。此外,Genkwadaphnin在小鼠体内显现出能显著抑制去势抵抗性前列腺癌(CRPC)发展的抗癌活性。 | |||
TN6130 |
Isodihydrocadambine
|
||
Isodihydrocadambine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6130,CAS号为 55624-02-7。 | |||
TN2318 |
Yadanziolide C
|
Others | Others |
Yadanziolide C induces differentiation with cultured HL-60 promyelocytic leukemia cells. | |||
TN6095 |
Cadambine
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Cadambine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6095,CAS号为 54422-49-0。 | |||
TN4390 |
Kihadanin B
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Akt; PPAR; FOXO1 | Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling |
Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes. | |||
TN4389 |
Kihadanin A
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Others | Others |
Kihadanin A is a natural product from Phellodendron amurense. | |||
T35234 |
Yadanzioside B
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Yadanzioside B 是提取自鸦胆子的苦木素苷类化合物。Yadanzioside B 能够抑制HeLa细胞中的蛋白质合成,但对体外翻译几乎没有影响。 | |||
T8733 |
Antrodin A
(2-氯苯基)二苯基甲醇,camphorataanhydride A |
Others | Others |
Antrodin A (camphorataanhydride A) 是固体发酵樟脑菌菌丝体的一种主要活性成分。它能够增强肝脏的抗炎及抗氧化能力,维持肠道菌群的稳定,避免酒精对肝脏的损伤。 | |||
TN1736 |
Hibifolin
棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷 |
Adenosine deaminase | Metabolism |
Hibifolin 是一种黄酮醇糖苷,是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。 | |||
TN1550 |
Danshenxinkun A
丹参新醌甲,丹参新醌A |
Others | Others |
Danshenxinkun A, Danshenxinkun B and Neocryptotanshinone may intervene thrombotic diseases by adjusting the targets mainly involved in pathways of endocrine system, signal transduction, signaling molecules and interaction, cell motility, environmental ada |
Cat. No. | Product Name | Species | Expression System |
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TMPY-03985 |
Adenosine Deaminase Protein, Human, Recombinant (His)
ADA1,adenosine deaminase,ADA |
Human | Baculovirus Insect Cells |
Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation and function of T and B lymphocytes. Adenosine deaminase is a polymorphic enzyme that has an important role in immune functions and in the regulation of intracellular and extracellular concentrations of adenosine and adenosine receptor activity. ADA activity might be considered as... | |||
TMPY-00516 |
CECR1 Protein, Human, Recombinant (His)
adenosine deaminase 2,ADA2,IDGFL,ADGF,CECR1 |
Human | Baculovirus Insect Cells |
CECR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is AAH51755.1. | |||
TMPK-00933 |
ADAM8/CD156a Protein, Mouse, Recombinant (His)
CD156a,MGC134985,ADAM 8,Ms2,Adam8 |
Mouse | HEK293 Cells |
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... | |||
TMPH-02485 |
ADAMTS5 Protein, Mouse, Recombinant (His)
Implantin,ADAMTS-5,ADAM-TS 5,ADMP-2,Aggrec... |
Mouse | E. coli |
ADAMTS5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.8 kDa and the accession number is Q9R001. | |||
TMPK-00553 |
ADAM9 Protein, Cynomolgus, Recombinant (His)
Adam9,CORD9,mKIAA0021,Meltrin-γ,Meltrin-gamma,A... |
Cynomolgus | HEK293 Cells |
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS. | |||
TMPH-03421 |
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) VP7 Protein (His & Myc)
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RV-A | E. coli |
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) VP7 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.0 kDa and the accession number is A8D8S8. | |||
TMPH-00581 |
ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)
yljA,ATP-dependent Clp protease adapter protein Clp... |
E. coli | E. coli |
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.2?kDa and the accession number is P0A8Q6. | |||
TMPY-03877 |
ADAM8/CD156a Protein, Rhesus, Recombinant (His)
ADAM metallopeptidase domain 8 |
Rhesus | HEK293 Cells |
ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.6 kDa and the accession number is XP_002805919.1. | |||
TMPH-00959 |
AADAC Protein, Human, Recombinant (His & Myc & SUMO)
EC:3.1.1.3,DAC,AADAC,Arylacetamide deacetylase |
Human | E. coli |
AADAC Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-02484 |
ADAMTS13 Protein, Mouse, Recombinant (His & Myc)
ADAM-TS 1,A disintegrin and metalloproteinase with ... |
Mouse | E. coli |
Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. ADAMTS13 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.7 kDa and the accession number is Q769J6. | |||
TMPH-02629 |
ADAM12 Protein, Mouse, Recombinant (His & Myc)
Disintegrin and metalloproteinase domain-containing protein ... |
Mouse | Baculovirus Insect Cells |
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.4 kDa and the accession number is Q61824. | |||
TMPH-01234 |
ADAM33 Protein, Human, Recombinant (His)
C20orf153,Disintegrin and metalloproteinase domain-containin... |
Human | Baculovirus Insect Cells |
ADAM33 Protein, Human, Recombinant (His) is expressed in Baculovirus with C-terminal 6xHis tag. The predicted molecular weight is 78.0 kDa. Accession number: Q9BZ11 | |||
TMPH-01249 |
ADAR Protein, Human, Recombinant (GST)
DRADA,K88DSRBP,p136,136 kDa double-stranded RNA-bin... |
Human | E. coli |
ADAR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 47.2 kDa and the accession number is P55265. | |||
TMPY-00961 |
ADAM15 Protein, Human, Recombinant (His)
MDC15,ADAM metallopeptidase domain 15 |
Human | HEK293 Cells |
ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10. | |||
TMPY-05932 |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His)
NA Protein |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0G3XQY1. | |||
TMPY-02280 |
ADAM15 Protein, Mouse, Recombinant (His)
metargidin,ADAM metallopeptidase domain 15,MDC15 |
Mouse | HEK293 Cells |
ADAM15 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 74.6 kDa and the accession number is O88839-1. | |||
TMPH-03047 |
NadA Protein, MenC, Recombinant (His)
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MenB | E. coli |
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. NadA Protein, MenC, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.1 kDa and the accession number is A1KVN9. | |||
TMPH-00868 |
ADAMTS7 Protein, Human, Recombinant (His & SUMO)
ADAM-TS7,ADAMTS-7,ADAM-TS 7,A dis... |
Human | E. coli |
Metalloprotease that may play a role in the degradation of COMP. ADAMTS7 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is Q9UKP4. | |||
TMPH-00448 |
SVMP Protein, Crotalus adamanteus, Recombinant (His)
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Crotalus adamanteus | E. coli |
Has no significant hemorrhagic activity, but inactivates serpins by limited proteolysis of their reactive-site loops. SVMP Protein, Crotalus adamanteus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.1 kDa and the accession number is P34179. | |||
TMPH-03045 |
NadA Protein, MenB, Recombinant (His)
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MenB | E. coli |
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | |||
TMPY-02404 |
ADAM9 Protein, Mouse, Recombinant (His)
mKIAA0021,AU020942,ADAM metallopeptidase domain 9,M... |
Mouse | HEK293 Cells |
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential t... | |||
TMPY-01212 |
ADAM12 Protein, Human, Recombinant (His)
ADAM metallopeptidase domain 12,MLTNA,MCMP,CAR10,ML... |
Human | HEK293 Cells |
The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities. Human ADAM12, which is implicated in diseases such as cancer, is expressed in two splice forms, the transmembrane ADAM12-L and the shorter and soluble ADAM12-S. ADAM12, also known as and Meltrin alpha, is a member of the ADAM protein family, which contains one disintegrin domain, one EGF-like domain and one peptidase M12B domain. ADAM12 is synthes... | |||
TMPK-00918 |
ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
CD156a,ADAM 8,MGC134985,Adam8,Ms2 |
Human | HEK293 Cells |
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... | |||
TMPY-05532 |
ADAM8/CD156a Protein, Human, Recombinant (His)
CD156,MS2,CD156a,ADAM metallopeptidase domain 8 |
Human | HEK293 Cells |
ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is Q14C66. | |||
TMPY-03308 |
ADAM17 Protein, Rat, Recombinant (His)
ADAM metallopeptidase domain 17 |
Rat | HEK293 Cells |
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative colitis, a main form of inflammatory bowel disease. The expression of ADAM17 may be inhibited by ethanol. It is involved in the processing of tumor necrosis factor alpha (TNF-α) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. ADAM1... | |||
TMPH-00866 |
ADAMTS14 Protein, Human, Recombinant (His)
A disintegrin and metalloproteinase with thrombospondin moti... |
Human | E. coli |
Has aminoprocollagen type I processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form. ADAMTS14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.2 kDa and the accession number is Q8WXS8. | |||
TMPY-05877 |
Influenza A H1N1 (A/swine/Canada/01093/2006) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Canada/01093/2006) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is A0A0G3XQS0. | |||
TMPH-02493 |
ADAMDEC1 Protein, Mouse, Recombinant (His)
A disintegrin and metalloproteinase domain-like protein decy... |
Mouse | E. coli |
May play an important role in the control of the immune response and during pregnancy. ADAMDEC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q9R0X2. | |||
TMPH-00891 |
ADAMTSL5 Protein, Human, Recombinant (His & Myc)
THSD6,ADAMTS-like protein 5,Thrombospondin type-1 d... |
Human | E. coli |
May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM). ADAMTSL5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.0 kDa and the accession number is Q6ZMM2. | |||
TMPJ-00665 |
ADAMDEC1 Protein, Human, Recombinant (His)
a disintegrin and metalloproteinase domain-like protein decy... |
Human | HEK293 Cells |
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy. | |||
TMPH-01596 |
AADAT Protein, Human, Recombinant (His & SUMO)
2-aminoadipate transaminase,Glycine transaminase AADA |
Human | E. coli |
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). | |||
TMPY-00298 |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H2N2 | Baculovirus Insect Cells |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q4ZH98. | |||
TMPH-00867 |
ADAMTS4 Protein, Human, Recombinant (GST)
ADAMTS-14,ADAM-TS 14,A disintegrin and met... |
Human | E. coli |
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. ADAMTS4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 39.0 kDa and the accession number is O75173. | |||
TMPH-00869 |
ADAMTS7 Protein, Human, Recombinant (His)
ADAM-TS7,ADAM-TS 7,COMPase,ADAMTS... |
Human | P. pastoris (Yeast) |
Metalloprotease that may play a role in the degradation of COMP. ADAMTS7 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is Q9UKP4. | |||
TMPY-06517 |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His)
NA Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.64 kDa and the accession number is AKM14549. | |||
TMPH-01248 |
ADAR Protein, Human, Recombinant (His & SUMO)
ADAR1,IFI-4,136 kDa double-stranded RNA-binding pro... |
Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri... | |||
TMPY-02954 |
ADAMTSL1 Protein, Human, Recombinant (His)
PUNCTIN,ADAMTSL-1,C9orf94,ADAMTS-like 1, |
Human | Baculovirus Insect Cells |
ADAMTSL1 is a secreted molecule resembling members of the ADAMTS protein family of matrix metalloproteinases. Both ADAMTS proteins and ADAM protein family contain a disintegrin and a metalloprotease domain. Metallospondins is collective term for members of ADAMTS protein family. ADAMTS proteins lack the EGF-like domain found normally in members of the ADAM protein family. They also do not possess the canonical disintegrin sequence found in the ADAM protein family. It contains the domains found i... | |||
TMPY-01495 |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H2N2 | HEK293 Cells |
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is Q4ZH98. | |||
TMPH-03279 |
DPP4/CD26 Protein, Rat, Recombinant (His & SUMO)
Dpp4,Dipeptidyl peptidase IV,DPP IV,CD26,Dipeptidyl peptidas... |
Rat | E. coli |
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular ... | |||
TMPH-00708 |
DegP Protein, E. coli, Recombinant (His)
Periplasmic serine endoprotease DegP,Heat shock protein DegP... |
E. coli | P. pastoris (Yeast) |
DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm following heat shock or other stress conditions. DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-spec... |