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6

抑制剂 & 化合物

41

天然产物

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Cat. No. Product Name Target Signaling Pathways
T7465 4-Methylbenzylidene camphor

Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC

AChE Neuroscience
4-Methylbenzylidene camphor 是有机的樟脑衍生物,应用于化妆品行业,具有保护皮肤抵抗紫外线(特别是紫外线B 辐射)的能力。
T16807 Rucaparib monocamsylate

瑞卡帕布樟脑磺酸盐,Rucaparib Camsylate

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Rucaparib monocamsylate (Rucaparib Camsylate) 是一种口服有效的 PARP 蛋白抑制剂,对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂,有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T5672 2,4-Diaminophenoxyethanol HCl

Others Others
2,4-Diaminophenoxyethanol HCl 是一种单萜,以及结构相关的 1,8-桉树脑和樟脑,已显示出对癌症的保护作用,对多种微生物的生物活性,和抗氧化特性。
T9048 Ecamsule

Others Others
Ecamsule 是一种亚苄基樟脑衍生物,其中许多以其出色的光稳定性而闻名。 可添加到防晒霜中以过滤掉 UVA 射线。
T33331 Methyl 3-hydroxybenzoate

Methyl 3-hydroxybenzoate is a bioactive chemical.
T20645 Laurifoline

Laurifoline is a potential inhibitor of NF-κB.

化合物

4-Methylbenzylidene camphor
Cat.No: T7465
Synonym: Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC
Target: AChE
Rucaparib monocamsylate
Cat.No: T16807
Synonym: 瑞卡帕布樟脑磺酸盐,Rucaparib Camsylate
Target: PARP
2,4-Diaminophenoxyethanol HCl
Cat.No: T5672
Synonym:
Target: Others
Ecamsule
Cat.No: T9048
Synonym:
Target: Others
Methyl 3-hydroxybenzoate
Cat.No: T33331
Synonym:
Target:
Laurifoline
Cat.No: T20645
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0882 (+)-Camphor

D-(+)-Camphor,D-Camphor,(+)-樟脑,(1R)-(+)-Camphor

Antibacterial; TRP/TRPV Channel Membrane transporter/Ion channel; Microbiology/Virology
(+)-Camphor (D-Camphor) 是一种食品添加剂,在医学上可用作防腐剂。
TMS2262 (-)-CAMPHOR

L-Camphor,左旋樟脑

Others Others
(-)-CAMPHOR (L-Camphor) 是樟脑的手性中间体,在食品中用作风味添加剂和甜味剂。
T2952 Camphor

樟脑,(±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa

Influenza Virus; TRP/TRPV Channel Membrane transporter/Ion channel; Microbiology/Virology
Camphor (2-Camphanone) 是一种双环单萜酮,广泛存在于植物中,尤其是樟脑。 它是一种激动剂,局部用作皮肤止痒剂和抗感染剂,具有抗病毒,镇咳和抗癌活性。
T20191 (-)-Camphoric acid

(-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-

GluR Neuroscience
(-)-Camphoric acid (L-Camphoric acid) 是一种活性较低的樟脑酸对映异构体,樟脑酸可诱导 GluR 表达。
T2981 Xanthoxylin

Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone

Others; Antifungal Microbiology/Virology; Others
Xanthoxylin (Brevifolin)e 是从Zanthoxylum simulans 中分离出来的是一种冰片和樟脑味化合物,有抗真菌和抗癫痫作用。
T0762 Trans-Anethole

茴香烯,(E)​-Anethole,4-Propenylanisole

Others; Endogenous Metabolite Metabolism; Others
Trans-Anethole ((E)​-Anethole) 是一种从Pimpinella 分离得到的苯丙烯衍生物,是茴香、桃金娘、甘草、樟脑等植物中重要气味的组成部分。它在肿瘤细胞系中,低浓度下有雌激素特性,而在高浓度下具有细胞毒性。
T8733 Antrodin A

(2-氯苯基)二苯基甲醇,camphorataanhydride A

Others Others
Antrodin A (camphorataanhydride A) 是固体发酵樟脑菌菌丝体的一种主要活性成分。它能够增强肝脏的抗炎及抗氧化能力,维持肠道菌群的稳定,避免酒精对肝脏的损伤。
T82002 Juniper camphor

Juniper camphor为倍半萜烯类化合物,可通过分馏樟脑蓝油的高沸点馏分进行分离。
T8088 Furfuryl acetate

乙酸糠醇酯,乙酸糠酯

Others Others
Furfuryl acetate 可用于合成 5-乙酰氧基甲基-2-呋喃和 5-羟甲基-2-呋喃。
TN1568 Deoxyartemisinin

2-deoxyartemisinin

Deoxyartemisinin (2-deoxyartemisinin) 是一种口服有效的抗炎和抗溃疡化合物,可从青蒿素青蒿中分离得到。
T21065 Artemisitene

Others Others
Artemisitene 是青蒿素的氧化形式,是一种抗疟药。青蒿素前体是青蒿素生物合成的重要基础物质,包括青蒿素 B、青蒿素、青蒿酸等。
T2754 Oxymatrine

Oxysophoridine,氧化苦参碱,Matrine N-oxide

Influenza Virus; Autophagy; TGF-beta/Smad Autophagy; Microbiology/Virology; Stem Cells
Oxymatrine (Oxysophoridine) 是来自槐属物种根部的一种生物碱,具有抗炎,抗纤维化和抗肿瘤的作用。它是一种用于治疗乙型肝炎病毒的中药。它可抑制博卡病毒 MVC 复制,降低病毒基因表达并减少病毒感染诱导的细胞凋亡。它还可以抑制 iNOS 的表达和 TGF-β/Smad 通路。
T22446 NADP disodium salt

Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Others Others
NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子,是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子,可以被交替氧化 (NADP+) 和还原 (NADPH)。
T0433 Artesunate

WR-256283,青蒿琥酯

Virus Protease; Ferroptosis; STAT; Parasite Apoptosis; JAK/STAT signaling; Microbiology/Virology; Stem Cells
Artesunate (WR-256283) 是治疗疟疾的青蒿素组药物的一部分。 它是青蒿素的半合成衍生物,具有水溶性。
T8948 Ferroheme

protoheme,Hematin,heme

Others Others
Ferroheme (protoheme) 是一种亚铁离子和卟啉的复合物,也是脂肪酸结合大鼠肝脏脂肪酸结合蛋白的同位异构抑制剂。
T4S1452 Artemisic acid

(+)-Artemisinic Acid,青蒿酸,Artemisinic acid

Antibacterial Microbiology/Virology
Artemisic acid ((+)-Artemisinic Acid) 是黄花蒿中分离得到的一种倍半萜,具有多种药理活性,如抗疟、抗菌和抗肿瘤活性,以及解热、化感和抗脂肪生成作用。
TN1039 Tamarixetin

柽柳黄素,4'-O-Methyl Quercetin

Endogenous Metabolite; Immunology/Inflammation related Immunology/Inflammation; Metabolism
Tamarixetin (4'-O-Methyl Quercetin) 是一种槲皮素的天然类黄酮衍生物,具有抗氧化、抗炎作用,能够防止心肌肥厚。
T6S1538 Neochlorogenic acid

新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid

TNF; NF-κB; COX; Antibacterial; Interleukin Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) 是在干果和其他植物中发现的一种多酚类天然产物,可抑制iNOS 和COX-2蛋白表达,抑制TNF-α和IL-1β产生,还抑制磷酸化的NF-κB p65和p38 MAPK 活化。
T3254 PHYTOL

植醇,trans-Phytol,(E)-Phytol

Antibacterial; PPAR; Parasite DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
PHYTOL (trans-Phytol) 是一种从叶绿素中提取的二萜醇,广泛应用于食品添加剂和医药领域,具有很好的抗血吸虫特性。它具有抗伤害、抗氧化、抗炎、抗过敏等作用。它对结核分枝杆菌和金黄色葡萄球菌具有抗菌活性。
TN1296 5-Feruloylquinic acid

5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸

Tyrosinase; Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
5-Feruloylquinic acid (5-FQA) 表现出抗氧化作用和酪氨酸酶抑制作用。
T8086 Decyl aldehyde

Others; Endogenous Metabolite Metabolism; Others
Decyl aldehyde 是细菌荧光素酶底物,是十碳醛。
T2S1158 4,5-Dicaffeoylquinic acid

3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C

Others; HBV; Endogenous Metabolite Metabolism; Microbiology/Virology; Others
4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) 是一种天然产物,有抗病毒、抗肝毒性活性。
TN2386 (±)-Lariciresinol

Others Others
(±)-Lariciresinol is a natural product from plants
TN4572 Mirandin B

Others Others
Mirandin B是一种天然产物,属于樟科蜜樟属,其产品编号为 TN4572,CAS号为 62163-24-0。Mirandin B可用作对照参考。
TN2509 (2S)-2alpha-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5alpha-methoxy-3beta-methyl-5-allyl-2H-benzofuran-6-one

Others Others
(2S)-2alpha-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5alpha-methoxy-3beta-methyl-5-allyl-2H-benzofuran-6-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2509,CAS号为 57430-03-2。
TN1834 Kobusin

去甲槟郎碱,自旋七叶素

Others; NOS; NF-κB Immunology/Inflammation; NF-κB; Others
Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-express...
TN5528 Mikanin

Mikanin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5528,CAS号为 4324-53-2。
TN3473 Axillarin

Axillarin has antioxidant activity, it shows xanthine oxidase inhibitory activity ( IC(50) :36.0 uM). Axillarin can strongly protect primary cultured neurons against glutamate-induced oxidative stress.
TN6143 5-Hydroxy-3,6,7,4'-tetramethoxyflavone

5-Hydroxy-3,6,7,4'-tetramethoxyflavone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6143,CAS号为 14787-34-9。
T30435 Beta-terpineol

AI3-00731,AI3 00731,AI300731

Terpineol is a monoterpene alcohol that has been isolated from a variety of sources such as petitgrain oil.
TN6519 Saucerneol

Saucerneol has significant cardiovascular effects such as vasorelaxant and negative inotropic actions.
T3837 Mearnsetin

Antioxidant oxidation-reduction
Mearnsetin 具有抗氧化活性。
TN6014 Norcepharadione B

鱼腥草

Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3,
TN4489 Manassantin A

ERK; cAMP; TNF; NF-κB; MAPK; COX; HIF; Prostaglandin Receptor; JNK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB act
TN3451 Arteannuin A

Others Others
Arteannuin A is a natural product from Artemisia annua.
TN3444 Aristolactam BII

HIV Protease Microbiology/Virology; Proteases/Proteasome
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts its significant neuroprotective ef
TN4490 Manassantin B

ERK; BCL; p38 MAPK; TNF; NF-κB; JNK; STAT; Antifection Apoptosis; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in pa...
TN3443 Aristolactam AII

PAFR GPCR/G Protein
Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity.
T21101 1-Decanol

1-Hydroxydecane,Caprinic alcohol,Decyl alcohol,Decanol,n-Decanol,Alcohol C-10

1-Decanol is used in the production of lubricants, surfactants, plasticizers, and solvents. It is also used to study the thermal properties of polymer-monolithic stationary phases and is used to enhance the homomeric glycine receptor function. It is used
TN1062 Peonidin chloride

ERK; COX Immunology/Inflammation; MAPK; Neuroscience
Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast cancer cells.
TN1235 3,4,5-Tricaffeoylquinic acid

TNF; Akt; HIV Protease Apoptosis; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor 4 expression-mediated activation of the Akt, ERK and NF-κB pathways, it may exert an inhibitory effect against the pro-inflammatory mediator-induced skin disease.

天然产物

(+)-Camphor
Cat.No: T0882
Synonym: D-(+)-Camphor,D-Camphor,(+)-樟脑,(1R)-(+)-Camphor
Target: Antibacterial, TRP/TRPV Channel
(-)-CAMPHOR
Cat.No: TMS2262
Synonym: L-Camphor,左旋樟脑
Target: Others
Camphor
Cat.No: T2952
Synonym: 樟脑,(±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa
Target: Influenza Virus, TRP/TRPV Channel
(-)-Camphoric acid
Cat.No: T20191
Synonym: (-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-
Target: GluR
Xanthoxylin
Cat.No: T2981
Synonym: Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone
Target: Others, Antifungal
Trans-Anethole
Cat.No: T0762
Synonym: 茴香烯,(E)​-Anethole,4-Propenylanisole
Target: Others, Endogenous Metabolite
Antrodin A
Cat.No: T8733
Synonym: (2-氯苯基)二苯基甲醇,camphorataanhydride A
Target: Others
Juniper camphor
Cat.No: T82002
Synonym:
Target:
Furfuryl acetate
Cat.No: T8088
Synonym: 乙酸糠醇酯,乙酸糠酯
Target: Others
Deoxyartemisinin
Cat.No: TN1568
Synonym: 2-deoxyartemisinin
Target:
Artemisitene
Cat.No: T21065
Synonym:
Target: Others
Oxymatrine
Cat.No: T2754
Synonym: Oxysophoridine,氧化苦参碱,Matrine N-oxide
Target: Influenza Virus, Autophagy, TGF-beta/Smad
NADP disodium salt
Cat.No: T22446
Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐
Target: Others
Artesunate
Cat.No: T0433
Synonym: WR-256283,青蒿琥酯
Target: Virus Protease, Ferroptosis, STAT, Parasite
Ferroheme
Cat.No: T8948
Synonym: protoheme,Hematin,heme
Target: Others
Artemisic acid
Cat.No: T4S1452
Synonym: (+)-Artemisinic Acid,青蒿酸,Artemisinic acid
Target: Antibacterial
Tamarixetin
Cat.No: TN1039
Synonym: 柽柳黄素,4'-O-Methyl Quercetin
Target: Endogenous Metabolite, Immunology/Inflammation related
Neochlorogenic acid
Cat.No: T6S1538
Synonym: 新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid
Target: TNF, NF-κB, COX, Antibacterial, Interleukin
PHYTOL
Cat.No: T3254
Synonym: 植醇,trans-Phytol,(E)-Phytol
Target: Antibacterial, PPAR, Parasite
5-Feruloylquinic acid
Cat.No: TN1296
Synonym: 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸
Target: Tyrosinase, Sirtuin
Decyl aldehyde
Cat.No: T8086
Synonym:
Target: Others, Endogenous Metabolite
4,5-Dicaffeoylquinic acid
Cat.No: T2S1158
Synonym: 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C
Target: Others, HBV, Endogenous Metabolite
(±)-Lariciresinol
Cat.No: TN2386
Synonym:
Target: Others
Mirandin B
Cat.No: TN4572
Synonym:
Target: Others
(2S)-2alpha-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5alpha-methoxy-3beta-methyl-5-allyl-2H-benzofuran-6-one
Cat.No: TN2509
Synonym:
Target: Others
Kobusin
Cat.No: TN1834
Synonym: 去甲槟郎碱,自旋七叶素
Target: Others, NOS, NF-κB
Mikanin
Cat.No: TN5528
Synonym:
Target:
Axillarin
Cat.No: TN3473
Synonym:
Target:
5-Hydroxy-3,6,7,4'-tetramethoxyflavone
Cat.No: TN6143
Synonym:
Target:
Beta-terpineol
Cat.No: T30435
Synonym: AI3-00731,AI3 00731,AI300731
Target:
Saucerneol
Cat.No: TN6519
Synonym:
Target:
Mearnsetin
Cat.No: T3837
Synonym:
Target: Antioxidant
Norcepharadione B
Cat.No: TN6014
Synonym: 鱼腥草
Target:
Manassantin A
Cat.No: TN4489
Synonym:
Target: ERK, cAMP, TNF, NF-κB, MAPK, COX, HIF, Prostaglandin Receptor, JNK, STAT
Arteannuin A
Cat.No: TN3451
Synonym:
Target: Others
Aristolactam BII
Cat.No: TN3444
Synonym:
Target: HIV Protease
Manassantin B
Cat.No: TN4490
Synonym:
Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection
Aristolactam AII
Cat.No: TN3443
Synonym:
Target: PAFR
1-Decanol
Cat.No: T21101
Synonym: 1-Hydroxydecane,Caprinic alcohol,Decyl alcohol,Decanol,n-Decanol,Alcohol C-10
Target:
Peonidin chloride
Cat.No: TN1062
Synonym:
Target: ERK, COX
3,4,5-Tricaffeoylquinic acid
Cat.No: TN1235
Synonym:
Target: TNF, Akt, HIV Protease
TargetMol Loading
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