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70

抑制剂 & 化合物

13

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4508	Glycyl-L-Histidyl-L-Lysine	Others	Others
	Glycyl-L-Histidyl-L-Lysine 是一种肝细胞生长因子和一种合成的肝营养剂，可刺激肝红细胞生成因子的产生。
T2014	CCG-1423 CCG1423	LRRK2; Rho; Ras	Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CCG-1423 是一种选择性 RhoA 通路抑制剂，可抑制 SRF 介导的转录，能抑制细胞的转移前列腺癌PC-3细胞侵袭模型。
T11765	KPLH1130	Dehydrogenase; PDK	Metabolism; PI3K/Akt/mTOR signaling
	KPLH1130，一种选择性丙酮酸脱氢酶激酶(PDK)抑制剂，在高脂饮食(HFD)喂养的小鼠中提高了糖耐量。KPLH1130 抑制巨噬细胞极化并减轻了炎症反应。
T7397	GSK547 GSK'547	RIP kinase	Apoptosis; NF-κB
	GSK547 (GSK'547) 是一种高选择性、强效的 RIP1激酶抑制剂，可抑制巨噬细胞介导的胰腺癌适应性免疫耐受。
T13692	Ferric maltol Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate,麦芽酚铁	Others	Others
	Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) 是一种具有口服活性的单一铁离子 (Fe3+) 复合物，可用于研究炎症性肠病缺铁性贫血。
T24695	Quinabactin LC-66C6,ABA mimics 1,AM1,LC66C6,LC 66C6	Others	Others
	Quinabactin (LC-66C6) 是一种有效的磺酰胺脱落酸 ABA 激动剂。Quinabactin 促进成年拟南芥和大豆植物的保卫细胞关闭、抑制水分流失，抑制种子萌发，提高耐旱性。
T27806	Lecozotan HCl SRA-333,SRA333,SRA 333,Lecozotan hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Lecozotan HCl (SRA-333) 是一种强效且具有选择性的 5-HT 拮抗剂。Lecozotan HCl能明显增强氯化钾刺激海马齿状回谷氨酸和乙酰胆碱的释放并具有增强认知能力的特性。在表明 5-HT(1A) 受体功能的行为模型中，长期服用Lecozotan HCl不会诱发 5-HT(1A) 受体耐受或脱敏。
T61202	TDO-IN-1	Others	Others
	TDO-IN-1 是一种具有口服活性、有效性和选择性的色氨酸 2,3-双加氧酶 (TDO)抑制剂，对吲哚胺-2,3-双加氧酶具有抑制作用。TDO-IN-1 具有抗肿瘤活性，能够通过逆转肿瘤组织的局部免疫耐受来发挥作用。
T3312	AM-2394 AM2394	Glucokinase	Metabolism
	AM-2394 是新型的 glucokinase 激活剂 (GKA)。它能够激活葡萄糖激酶 (GK)，EC50=60 nM。
T21979	P32/98 (hemifumarate)
	P32/98 hemifumarate 为二肽基肽酶 IV (DPP4) 抑制剂，可在Zucker糖尿病大鼠模型中改善葡萄糖耐量、提高胰岛素敏感性及增强β细胞反应性，具有预防2型糖尿病的潜力。
T0056	Oxeladin citrate	Others	Others
	Oxeladin citrate 是止咳剂，能够对各种病因引发咳嗽进行有效研究。
T38273	Paclobutrazol (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol	Antifungal	Microbiology/Virology
	Paclobutrazol ((R,R)-paclobutrazol) 是一种含有三唑的植物生长延缓剂，能抑制赤霉素的生物合成。Paclobutrazol 还具有抗真菌 (antifungal) 活性。Paclobutrazol 能抑制脱落酸的合成，诱导植物的耐冷性植物。Paclobutrazol 通常用于赤霉素在植物生物学中作用的研究。
T62238	AMPK activator 4	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	AMPK activator 4 是一种有效且具有选择性的AMPK激活剂，不抑制线粒体复合物 I。AMPK activator 4 选择性地激活肌肉组织中的 AMPK且剂量依赖性地改善正常小鼠的糖耐量，显著降低 db/db 糖尿病小鼠的空腹血糖水平和改善胰岛素抵抗。AMPK activator 4 具有降血糖作用。
T77577	SLU-PP-332	Estrogen/progestogen Receptor	Endocrinology/Hormones
	SLU-PP-332 是一种泛雌激素受体相关受体 (ERR) 激动剂，其对 ERRα, ERRβ 以及 ERRγ 具有很高的亲和力，EC50 值分别为 98、230 以及 430 nM。SLUPP-332 可增强骨骼肌细胞系的线粒体功能和细胞呼吸，增加 IIa 型氧化骨骼肌纤维并增强了运动耐力。SLU-PP-332 具有研究代谢性疾病以及肌肉功能改善的潜力，可能用于改善代谢紊乱和衰老。
T37610	AT-121	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	AT-121 是一种双重μ-阿片和神经肽受体部分激动剂（Kis 分别为 16.49 和 3.67 nM）。它能刺激[35S]GTPγS 与表达μ-阿片受体或神经肽受体的细胞膜结合（EC50s 分别为 19.6 和 34.7 nM）。AT-121（0.003-0.03 mg/kg）能以剂量依赖的方式降低辣椒素诱导的热异感，但不会增加恒河猴的搔抓活动。在恒河猴药物自我给药试验中，AT-121 每次注射剂量为 0.3 至 10 μg/kg，它缺乏强化作用（一种潜在的滥用标志），不能减少食物颗粒的强化作用。AT-121（0.01 或 0.03 毫克/千克）不会诱发恒河猴的超痛觉，超痛觉是产生耐受性的标志。AT-121 是一种安全、无成瘾性的缓解疼痛药，具有抗伤害和止痛作用。
T37816	SB 243213
	SB 243213 is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. SB 243213 shows greater than a 100-fold selectivity over a wide range of neurotransmitter receptors, enzymes and ion channels. SB 243213 has improved anxiolytic profile and has the potential for schizophrenia and motor disorders[1]. SB 243213 shows little affinity (pKi<6) for cloned human 5-HT1A, 5-HT1B, 5-HT1E, 5- HT1F and 5-HT7 receptors. It shows...
T29422	4-(Beta-aminoethyl)thiazole
	4-(Beta-aminoethyl)thiazole is a histamine analog which can induce cross-tolerance to histamine.
T28784	SIRT6-IN-1
	SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.
T38771	P32/98 P32/98
	P32/98 is a potent inhibitor of dipeptidyl peptidase IV . P32/98 improves glucose tolerance, insulin sensitivity and β-cell responsiveness in preclinical studies using the fatty Zucker rat, an animal model for IGT (impaired glucose tolerance).
T30169	ASP-8497 UNII-GC7THT248G,ASP8497,ASP 8497
	ASP8497 is a potent, long-acting DPP-IV inhibitor that improves glucose tolerance by elevating GLP-1 levels in a glucose-dependent insulin-stimulating manner. The compound is used as a therapeutic agent for impaired glucose tolerance and type 2 diabetes.
T28067	ML372 ML 372,ML-372
	ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.
T34921	Tresperimus LF08-0299,LF 08-0299,LF-08-0299
	Tresperimus can induce tolerance after the short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model.
T34921L	Tresperimus HCl Tresperimus trihydrochloride,LF08-0299 trihydrochloride,LF 08-0299 trihydrochloride,LF-08-0299 trihydrochloride
	Tresperimus HCl can induce tolerance after the short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model.
T11583	HWL-088	Others	Others
	HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.
TP1539	AtPep3
	AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants.
TP1614	AtPep3 TFA (902781-14-0 free base) AtPep3 TFA
	AtPep3 TFA is a hormone-like peptide that plays a role in the salinity stress tolerance of plants.
T69607	Dersimelagon phosphate
	Dersimelagon phosphate is a selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure and is being developed to increase light tolerance in EPP/XLP patients.
T61155	D-Cl-amidine hydrochloride
	D-Cl-amidine hydrochloride is a potent and highly selective inhibitor of PAD1. It exhibits excellent tolerance and does not induce significant toxicity [1].
T69853	AR-C117977
	AR-C117977 is a potent MCT1 inhibitor, which can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance.
T68132	quercetin-3'-o-phosphate
	Quercetin-3'-O-phosphate belongs to the class of organic compounds known as flavonols,has been used in trials studying the treatment of Insulin Resistance and Impaired Glucose Tolerance.
T29154	WB403 WB-403,WB 403
	WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores the normal distribution pattern of α-
T71251	DS-1558
	DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDF rats. DS-1558 significantly and dose-dependently improved hyperglycemia and increased insulin secretion during the oral glucose tolerance test in Zucker fatty rats, the model of insulin resistance and glucose intolerance. DS-1558 not only increased the glucose-stimulated insulin secretion by GLP-1 but also potentiated the maximum insulinog...
T82942	AtPep3 TFA
	AtPep3 TFA 为一种具激素特性的肽类化合物，能够提升植物对盐分的耐受能力，并能防止盐分诱导下幼苗叶绿素发生漂白现象。
T78075	GBT1118	Others	Others
	GBT1118是一种有效的口服血红蛋白氧亲和力变构调节剂，可增强对严重缺氧的耐受性。
T61798	PARP-1-IN-1
	PARP-1-IN-1 is a highly selective and orally active inhibitor of the enzyme PARP-1, with an IC50 value of 0.96 nM. It exhibits excellent tolerance and demonstrates significant activity in a single dose in the MDA-MB-436 xenotransplantation model [1].
T21921	Valeroyl Salicylate 2-Valeryloxybenzoic acid,戊酰基水杨酸	Others	Others
	Valeroyl Salicylate (2-Valeryloxybenzoic acid) 具有抗炎作用，可延长寿命，延缓随年龄增长而导致的自发活动下降，并提高抗压能力。
TP2020	[Pro3]-GIP (Mouse)
	GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insul
T25739	Linogliride McN-3935,McN3935,McN 3935,Linogliridum,Linoglirida
	Linogliride 是一种基于胍的胰岛素分泌抑制剂，也是 pirogliride 的结构类似物，具有降血糖活性。它可以阻断胰腺β细胞膜上对 ATP 敏感的钾通道，从而刺激胰岛素分泌并改善葡萄糖耐受性。
T63320	Axl-IN-6
	Axl-IN-6 是口服具有活性的 AXL 抑制剂。Axl-IN-6 在 MV-4-11 皮下异种移植瘤模型中，表现出良好的耐受性，并且能够显著的抑制肿瘤生长。
T78354	Subtilisin EC 3.4.21.14
	Subtilisin，一种细菌来源的丝氨酸蛋白酶，通常作为洗涤剂添加剂使用，特征包括热稳定性、对pH的耐受性和钙依赖性稳定性。
TP2019	[D-Ala2]-GIP (human)
	Highly potent GIP receptor agonist (EC50 = 630 ± 119 pM). Displays equivalent cAMP stimulating properties and improved resistance to enzymatic degradation compared to native GIP in cells expressing wild type GIP receptor. Improves glucose tolerance, insul
T35785	N-Oleoyl Leucine
	N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro. N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO2 while slightly decreasing overall locomotor activity.
T35798	Massarigenin C
	Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 μM).2It is also an inhibitor of yeast α-glucosidase (IC50= 1.25 mM).1It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.
T25739L	Linogliride fumarate McN 3935,McN-3935,McN3935
	Linogliride fumarate 是Linogliride 的富马酸盐。Linogliride 是一种基于胍的胰岛素分泌抑制剂，也是pirogliride 的结构类似物，具有降血糖活性。它可以阻断胰腺β细胞膜上对ATP 敏感的钾通道，从而刺激胰岛素分泌并改善葡萄糖耐受性。
T79475	GPR119 agonist 2
	GPR119 agonist2（化合物43）是一种口服活性的GPR119激动剂。在啮齿动物中表现出优良的药代动力学特性，并能有效提高小鼠和大鼠的葡萄糖耐受性。GPR119 agonist2有望用于研究II型糖尿病。
T11056	DLK-IN-1	DNA Alkylation	DNA Damage/DNA Repair
	DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration
T79649	CB1R/AMPK modulator 1	Cannabinoid Receptor	GPCR/G Protein
	CB1R/AMPK modulator 1 (Compound 38-S)为一种口服活性CB1R/AMPK调节剂，具有0.81 nM的Ki及3.9 nM的CB1R IC50。该化合物能够激活AMPK，且能降低食物摄入量和体重，同时改善葡萄糖耐量与胰岛素敏感性。
T60312	FBPase-IN-1
	FBPase-IN-1 is a powerful inhibitor of Fructose-1,6-bisphosphatase (FBPase), a key enzyme involved in Type 2 diabetes (T2D) research. It exhibits an impressive IC50 value of 0.22 μM. Aside from its potency, FBPase-IN-1 also demonstrates the ability to effectively lower blood glucose levels and improve glucose tolerance. Its mechanism of action involves covalently modifying the C128 site, thereby influencing the N125-S124-S123 allosteric pathway of FBPase, ultimately impacting its catalytic activ...
T62542	GPR40 agonist 5
	GPR40 agonist 5 是一种口服具有活力的 GPR40 (G 蛋白偶联受体 40) 激动剂 (EC50: 47 nM)。GPR40 agonist 5 能够减少血糖水平，改善糖耐量。GPR40 agonist 5 对 2 型糖尿病小鼠的高血糖状态表现出充足的控制作用。
T75028	TMV-IN-4
	TMV-IN-4（compound 3）是一种针对烟草花叶病毒（TMV）的抑制剂。该化合物通过与TMV解旋酶交互作用，能够诱导植物产生抗性并提高对TMV感染的耐受性。TMV-IN-4还可增强过氧化物酶和超氧化物歧化酶活性，从而提升烟草的TMV抗性。

化合物

Glycyl-L-Histidyl-L-Lysine

Cat.No: T4508

Target: Others

Cat.No: T2014

Synonym: CCG1423

Target: LRRK2, Rho, Ras

Cat.No: T11765

Target: Dehydrogenase, PDK

Cat.No: T7397

Synonym: GSK'547

Target: RIP kinase

Cat.No: T13692

Synonym: Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate,麦芽酚铁

Target: Others

Cat.No: T24695

Synonym: LC-66C6,ABA mimics 1,AM1,LC66C6,LC 66C6

Target: Others

Cat.No: T27806

Synonym: SRA-333,SRA333,SRA 333,Lecozotan hydrochloride

Target: 5-HT Receptor

Cat.No: T61202

Target: Others

Cat.No: T3312

Synonym: AM2394

Target: Glucokinase

P32/98 (hemifumarate)

Cat.No: T21979

Oxeladin citrate

Cat.No: T0056

Target: Others

Cat.No: T38273

Synonym: (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol

Target: Antifungal

AMPK activator 4

Cat.No: T62238

Target: AMPK

Cat.No: T77577

Target: Estrogen/progestogen Receptor

Cat.No: T37610

Target: Opioid Receptor

Cat.No: T37816

4-(Beta-aminoethyl)thiazole

Cat.No: T29422

Cat.No: T28784

Cat.No: T38771

Synonym: P32/98

Cat.No: T30169

Synonym: UNII-GC7THT248G,ASP8497,ASP 8497

Cat.No: T28067

Synonym: ML 372,ML-372

Cat.No: T34921

Synonym: LF08-0299,LF 08-0299,LF-08-0299

Tresperimus HCl

Cat.No: T34921L

Synonym: Tresperimus trihydrochloride,LF08-0299 trihydrochloride,LF 08-0299 trihydrochloride,LF-08-0299 trihydrochloride

Cat.No: T11583

Target: Others

Cat.No: TP1539

AtPep3 TFA (902781-14-0 free base)

Cat.No: TP1614

Synonym: AtPep3 TFA

Dersimelagon phosphate

Cat.No: T69607

D-Cl-amidine hydrochloride

Cat.No: T61155

Cat.No: T69853

quercetin-3'-o-phosphate

Cat.No: T68132

Cat.No: T29154

Synonym: WB-403,WB 403

Cat.No: T71251

Cat.No: T82942

Cat.No: T78075

Target: Others

Cat.No: T61798

Valeroyl Salicylate

Cat.No: T21921

Synonym: 2-Valeryloxybenzoic acid,戊酰基水杨酸

Target: Others

[Pro3]-GIP (Mouse)

Cat.No: TP2020

Cat.No: T25739

Synonym: McN-3935,McN3935,McN 3935,Linogliridum,Linoglirida

Cat.No: T63320

Cat.No: T78354

Synonym: EC 3.4.21.14

[D-Ala2]-GIP (human)

Cat.No: TP2019

N-Oleoyl Leucine

Cat.No: T35785

Cat.No: T35798

Linogliride fumarate

Cat.No: T25739L

Synonym: McN 3935,McN-3935,McN3935

GPR119 agonist 2

Cat.No: T79475

Cat.No: T11056

Target: DNA Alkylation

CB1R/AMPK modulator 1

Cat.No: T79649

Target: Cannabinoid Receptor

Cat.No: T60312

GPR40 agonist 5

Cat.No: T62542

Cat.No: T75028

Cat. No.	Product Name	Target	Signaling Pathways
PDK0101	4-Methylcinnamic acid 对甲基肉桂酸,对甲基肉桂	Antifungal	Microbiology/Virology
	4-Methylcinnamic acid 是一种肉桂酸类似物，可用作克服抗真菌耐受性的干预催化剂。它可提高细胞壁破坏剂的效力。
T5S0669	Bergamottin 5-Geranoxypsoralen,Bergamotine,Bergaptin,佛手柑素	P450	Metabolism
	Bergamottin (5-Geranoxypsoralen) 是竞争性CYP1A1抑制剂(Ki:10.703 nM)。
T9790	Lactoferrin Lactoferrin (Bovine)	Endogenous Metabolite	Metabolism
	Lactoferrin 由哺乳动物分泌，具有广泛的生物学作用，包括提高应用良好的益生菌菌株的耐寒性。
T2740	trans-Cinnamic acid Isocinnamic acid,反式肉桂酸,Cinnamic acid,trans-3-Phenylacrylic acid,Phenylacrylic acid,Cinnamylic acid,3-Phenylacrylic acid,肉桂酸,Myricitrine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	trans-Cinnamic acid (Myricitrine) 通过改善体内葡萄糖耐量和体外刺激胰岛素分泌而发挥抗糖尿病活性。它是一种杀菌剂，对鱼的病原菌温和气单胞菌的 MIC 值为 250 μg/mL。
T5S0662	Gelsemine 钩吻碱,Gelsemin	Antioxidant	oxidation-reduction
	Gelsemine (Gelsemin) 是一种从中草药 Gelsemium elegans 中获得的生物碱，具有抗伤害和促进睡眠活性，可有效缓解慢性疼痛。
T4785	Oxfenicine 4-羟基-L-苯甘氨酸,4-Hydroxy-L-phenylglycine	Others	Others
	Oxfenicine (4-Hydroxy-L-phenylglycine) 是具有口服活性的肉碱棕榈酰转移酶-1 抑制剂。它在缺血期间保护心脏免受坏死组织的损害。它可抑制心脏中脂肪酸的氧化。
T3849	Kinsenoside 金线莲苷,(+)-Kinsenoside	Apoptosis; Nrf2	Apoptosis; Immunology/Inflammation
	Kinsenoside ((+)-Kinsenoside) 是从金盏花属植物中分离得到的主要活性成分，以 Nrf2 依赖的方式保护髓核细胞在氧化应激下的生存能力，防止细胞凋亡、衰老和线粒体功能障碍。它显示出显着的抗肝毒性和抗炎活性。
T38596	9,10-Dihydroxystearic acid
	9,10-Dihydroxystearic acid, an oxidation derivative of oleic acid, exhibits beneficial effects on glucose tolerance and insulin sensitivity in KKAy mice.
T38394	PSMα3
	PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation process induced by TLR2 or TLR4. Additionally, PSMα3 inhibits the production of both pro- and anti-inflammatory cytokines and decreases antigen uptake. Notably, PSMα3 is a significant virulence factor released by the most pathogenic strains of methicillin-resistant Staphylococcus...
T36348	Cerebroside C
	Cerebroside C is a fungal metabolite and glycosphingolipid that has been found in the rice pathogenic fungusM. grisea.1It induces production of the phytoalexin momilactone A when applied to wounded rice leaves, indicating that cerebroside C is an elicitor of the hypersensitive response in rice. Cerebroside C increases germination rate and reduces germination time in wheat seeds in a concentration-dependent manner at 4°C.2It also increases root length, fresh weight, and dry weight of wheat seedli...
T80007	Stevisalioside A	Phosphatase	Metabolism
	Stevisalioside A (Compound 2)，一种从甜叶菊根提取的化合物，展现出抗糖尿病的口服活性。该化合物有效抑制PTP1B，IC50为526.8 μM，并能降低Stevisalioside A引起的高血糖小鼠血糖水平，改善餐后血糖峰值及口服葡萄糖和胰岛素耐量测试结果。
T73074	Phanginin A
	Phanginin A 是有效的口服活性SIK1激活剂，通过抑制糖异生、增加p-SIK1表达及降低p-CREB表达，达到降低血糖水平、改善葡萄糖耐量和血脂异常的效果，显示出其在2型糖尿病研究中的潜力。
TN3070	4beta-Hydroxywithanolide E	PARP; HSP; NF-κB; COX	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by mo

天然产物

4-Methylcinnamic acid

Cat.No: PDK0101

Synonym: 对甲基肉桂酸,对甲基肉桂

Target: Antifungal

Cat.No: T5S0669

Synonym: 5-Geranoxypsoralen,Bergamotine,Bergaptin,佛手柑素

Target: P450

Cat.No: T9790

Synonym: Lactoferrin (Bovine)

Target: Endogenous Metabolite

trans-Cinnamic acid

Cat.No: T2740

Synonym: Isocinnamic acid,反式肉桂酸,Cinnamic acid,trans-3-Phenylacrylic acid,Phenylacrylic acid,Cinnamylic acid,3-Phenylacrylic acid,肉桂酸,Myricitrine

Target: Endogenous Metabolite, Antibacterial

Cat.No: T5S0662

Synonym: 钩吻碱,Gelsemin

Target: Antioxidant

Cat.No: T4785

Synonym: 4-羟基-L-苯甘氨酸,4-Hydroxy-L-phenylglycine

Target: Others

Cat.No: T3849

Synonym: 金线莲苷,(+)-Kinsenoside

Target: Apoptosis, Nrf2

9,10-Dihydroxystearic acid

Cat.No: T38596

Cat.No: T38394

Cat.No: T36348

Stevisalioside A

Cat.No: T80007

Target: Phosphatase

Cat.No: T73074

4beta-Hydroxywithanolide E

Cat.No: TN3070

Target: PARP, HSP, NF-κB, COX

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