795
83
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38796L |
MBP MAPK Substrate acetate
MBP MAPK Substrate acetate(138028-00-9 free base) |
MAPK | MAPK |
MBP MAPK Substrate acetate 可用作 MAPK 的外源性底物。 | |||
TP1483L |
Abl Cytosolic Substrate acetate
Abl Cytosolic Substrate acetate(168202-46-8 free base) |
Others | Others |
Abl Cytosolic Substrate acetate(168202-46-8 free base) 是 Abelson 酪氨酸激酶 (Abl) 的底物。 | |||
TP1485L |
Calcineurin substrate acetate
|
Autophagy | Autophagy |
Calcineurin substrate acetate 来自 cAMP 依赖性蛋白激酶的调节 RII 亚基。 | |||
T13799 |
NQO1 substrate
|
NADPH | Metabolism |
NQO1 substrate 是一种高效的 NQO1 底物,具有潜在的抗肿瘤活性,可用于研究白血病。 | |||
T37207L |
Cdk5 Substrate acetate
|
CDK | Cell Cycle/Checkpoint |
Cdk5 Substrate acetate 是一种丝氨酸/苏氨酸激酶,主要在神经元组织中具有活性。与 p25 或 p35 一起,Cdk5 磷酸化一系列蛋白质,包括组蛋白 H1 和 tau。 它是一种合成肽 (PKTPKKAKKL),对应于组蛋白 H1 的序列。它被 Cdk5 磷酸化,Km 值为 5 µM。 | |||
TP2205L |
DAPK Substrate Peptide acetate
|
DAPK | Apoptosis |
DAPK Substrate Peptide acetate 是一种死亡相关蛋白激酶 (DAPK, Km = 9 μM) 肽底物。 | |||
T37504L |
Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) |
||
Cathepsin D and E FRET Substrate acetate 是组织蛋白酶 D 和 E 的荧光底物,但不适用于 B、H 或 L。Cathepsin D and E FRET Substrate acetate 可用于组织蛋白酶 D 和 E 研究的机理研究。 | |||
TP1051L |
Protein Kinase C Peptide Substrate acetate
Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) |
Others | Others |
Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) 以依赖于第二信使和特定衔接蛋白的方式靶向特定细胞间隔物,以响应激活 g 蛋白偶联受体、酪氨酸激酶受体或酪氨酸激酶偶联受体的细胞外信号。 | |||
TP1787L |
PKG Substrate acetate(81187-14-6 free base)
|
PKA | Tyrosine Kinase/Adaptors |
PKG Substrate acetate(81187-14-6 free base) 是 cGMP 依赖性蛋白激酶 (PKG) 的选择性底物。PKG Substrate 是蛋白激酶 G (PKG) 的选择性底物,PKG Iα (Km = 59 µM) 优于 PKG II (Km = 305)微米)。 | |||
TP1417L |
Sakamototide substrate peptide acetate
|
Others | Others |
Sakamototide substrate peptide acetate 是 AMPK 激酶家族的肽底物,可用于激酶活性的测定。 | |||
T77698 |
hCYP3A4 Fluorogenic substrate 1
|
Others | Others |
hCYP3A4 Fluorogenic substrate 1 是邻苯二甲酰亚胺衍生物,对 COX 表现出低活性。 | |||
T37207 |
Cdk5 Substrate
Cdk5 Substrate |
||
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 μM. | |||
T83754 |
PKCδ Substrate TFA
Protein Kinase Cδ Substrate |
||
PKCδ substrate是一种用于PKCδ的肽基底,常用于无细胞及细胞内测定中监测PKCδ活性。 | |||
T83759 |
MMP-3 Fluorogenic Substrate TFA
Mca-RPKPVE-Nval-WR-K(Dnp)-NH2,Matrix Metalloproteinase-3 Fluorogenic Substrate,Stromelysin-1 Fluorogenic Substrate |
||
MMP-3 fluorogenic substrate 是一种针对基质金属蛋白酶-3(MMP-3)的荧光底物。当被MMP-3切割后,7-甲氧基香豆素-4-乙酰基(Mca)会释放并且其荧光可用于量化MMP-3活性。Mca的激发/发射峰值分别为328/420 nm。 | |||
T39383 |
Lipase Substrate
|
||
Lipase Substrate is a substrate of lipase to detect activity. | |||
T37021 | Enteropeptidase Fluorogenic Substrate | ||
Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage. Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ac... | |||
T38796 |
MBP MAPK Substrate
|
||
MBP MAPK Substrate is used as an exogenous substrate for MAPK. | |||
T35880 | Renin Fluorogenic Substrate | ||
The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleavage by renin, the product (peptide-EDANS) is brightly fluorescent and can be easily analyzed using an excitation wavelength of 340 nm and emission wavelengths of 485-510 nm. | |||
TP1787 |
PKG Substrate
|
||
PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with a strong preference for PKG Iα (Km = 59 µM) over PKG II (Km = 305 µM). | |||
TP1485 |
Calcineurin substrate
|
||
Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase. | |||
T40976 |
Syk Kinase Peptide Substrate
|
||
Syk Kinase Peptide Substrate is a Syk kinase peptide substrate. | |||
T39149 |
Src Optimal Peptide Substrate
|
||
Src Optimal Peptide Substrate, a highly specific substrate of Src, serves as a reliable indicator of Src activity. It enables accurate assessment of Src kinase function. | |||
T38900 |
Renin FRET Substrate I
|
||
Renin FRET Substrate I is a specific compound that functions as a substrate for human renin. It is specifically designed to contain the exact cleavage site found in the N-terminal peptide of human angiotensinogen. | |||
T39729 |
HIV Protease Substrate 1
|
||
HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect. | |||
TP1841 |
MARK Substrate
|
||
MARK Substrate is a MARK substrate peptide. | |||
T11582 |
HSV-TK substrate
|
Others | Others |
HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. | |||
TP1602 |
[pThr3]-CDK5 Substrate
|
||
[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate.[pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1]. | |||
T37022 |
Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)
|
||
Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage.1,2Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ... | |||
T41099 |
EGFR Protein Tyrosine Kinase Substrate
|
||
EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate. | |||
TP1398 |
Calcineurin substrate (TFA)
|
||
Calcineurin substrate (TFA) is a polypeptide derived from the regulatory RII subunit of camp-dependent protein kinase.Calcineurin substrate (TFA) can be used to determine the activity of Calcineurin. | |||
TP1483 |
Abl Cytosolic Substrate
|
||
Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). | |||
TP2205 |
DAPK Substrate Peptide
|
Others | Others |
DAPK Substrate Peptide is a synthetic peptide substrate for death-associated protein kinase (DAPK) (Km = 9 μM). | |||
T40945 |
Phospho-Glycogen Synthase Peptide-2(substrate)
|
||
Phospho-Glycogen Synthase Peptide-2, a substrate for glycogen synthase kinase-3 (GSK-3), serves as a peptide substrate effective in the affinity purification of protein-serine kinases. | |||
TP1660 |
[pThr3]-CDK5 Substrate (TFA)
|
||
[pThr3]-CDK5 Substrate TFA is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM. | |||
TP2175 |
Akt/SKG Substrate Peptide
|
Others | Others |
substrate for Akt/PKB | |||
TP1417 |
Sakamototide substrate peptide TFA
|
||
Sakamototide substrate peptide TFA is a peptide substrate of AMPK kinase family and can be used for the determination of kinase activity. | |||
TP2200 |
S6 Kinase Substrate Peptide 32
|
Others | Others |
S6 Kinase Substrate Peptide 32 is a peptide that measures the activity of kinases that phosphorylate ribosomal protein S6. It can also be used as a substrate. | |||
TP1634 |
Bacterial Sortase Substrate III, Abz/DNP
|
||
The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DN | |||
TP1807 |
EGF Receptor Substrate 2 Phospho-Tyr5
|
||
EGF Receptor Substrate 2 (Phospho-Tyr5) is a biologically active peptide derived from an autophosphorylation site (Tyr992) of EGFR. | |||
T37504 |
Cathepsin D and E FRET Substrate
|
||
Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A. | |||
TP1051 |
Protein Kinase C Peptide Substrate
PRKCE,Peptide Epsilon,PKCε |
||
Protein Kinase C Peptide Substrate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-coupled receptors, tyrosine Kinase receptors, or | |||
TP1322 |
Bacterial Sortase Substrate III, Abz/DNP (TFA)
|
||
Bacterial Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the f | |||
T82468 |
Endotoxin Substrate
|
||
Endotoxin Substrate (Boc-LGR-pNA) 为显色底物,专用于内毒素定量分析。 | |||
T78625 |
Z-Ala-Arg-Arg-AMC
Z-ARR-AMC,Fluorogenic Proteasome Substrate |
Proteasome | Proteases/Proteasome; Ubiquitination |
Z-Ala-Arg-Arg-AMC (FluorogenicProteasomeSubstrate) 作为荧光底物,专用于检测蛋白酶体中的胰蛋白酶样活性。 | |||
T75740 |
Calcineurin substrate TFA
|
||
Calcineurin substrate (TFA) 是来自 cAMP 依赖性蛋白激酶调节性RII 亚基的多肽。Calcineurin substrate (TFA) 可用于钙调神经磷酸酶活力的测定。 | |||
T76077 |
MMP-13 Substrate
|
||
MMP-13Substrate 是MMP-13的底物。MMP-13Substrate 可用于骨关节炎 (OA) 的研究。 | |||
T76490 |
Fluorescent HIV Substrate
|
||
FluorescentHIVSubstrate 是 HIV 底物。 | |||
T76412 |
PKCδ Peptide Substrate
|
||
PKCδPeptide Substrate 是一种δ-typePKC 的特异性底物,其序列与含有 Thr-431 的小鼠 eEF-1α 序列 422-443 相对应。 | |||
T76443 |
Renin substrate 1
|
||
Reninsubstrate 1 是一种对酶具有高亲和力的肾素 (renin) 底物。 | |||
T83711 |
Abl Substrate Peptide TFA
|
||
Abl底物多肽是酪氨酸激酶Abl的多肽底物。在20 µM浓度下,相较于c-Src激酶,它被Abl选择性磷酸化。Abl底物多肽已被用于体外定量Abl激酶活性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8091 |
trans-4-Hydroxycyclohexanecarboxylic Acid
|
Others | Others |
trans-4-Hydroxycyclohexanecarboxylic acid 是一种合成环己烷酸的底物 (substrate)。它是肠道细菌代谢的副产物 (by-product),能够通过尿路排泄。 | |||
T11351 |
Galanthamine N-Oxide
|
AChE | Neuroscience |
Galanthamine N-Oxide 是分离于Zephyranthes concolor 的球茎中的一种生物碱。它抑制电鳗乙酰胆碱酯酶,EC50=26.2 μM。它是TcAChE,hAChE 和 hBChE 酶活性位点中底物调节的显著抑制剂。 | |||
T4778 |
3-Hydroxybenzaldehyde
|
Others; Dehydrogenase | Metabolism; Others |
3-Hydroxybenzaldehyde 是很多酚类化合物的前体分子。它是人和大鼠醛脱氢酶 (ALDH) 的底物 (substrate)。它具有血管保护的作用。 | |||
TN5088 |
2,6-Dimethoxyphenol
Syringol,2,6-二甲氧基苯酚 |
Others | Others |
2,6-Dimethoxyphenol (Syringol) 是一种天然产物,可用于测量漆酶活性。 | |||
TQ0176 |
(-)-Isocorypalmine
Tetrahydrocolumbamine,(-)-异延胡索单酚碱,(S)-Tetrahydrocolumbamine |
Dopamine Receptor; Antifungal | GPCR/G Protein; Microbiology/Virology; Neuroscience |
(-)-Isocorypalmine ((S)-Tetrahydrocolumbamine) 是一种多巴胺受体配体,从延胡索粗碱中分离得到。重组CYP719A21 对 (-)-Isocorypalmine 具有严格的底物特异性和高亲和力 (Km=4.63 μM)。 | |||
T5087 |
DL-Isocitric acid trisodium salt
异柠檬酸三钠盐,Isocitric acid trisodium salt |
Others; Endogenous Metabolite | Metabolism; Others |
DL-Isocitric acid trisodium salt 是内源性代谢产物的一种。 | |||
TN1525 |
Convallatoxin
K-毒毛旋花子配质-3-L-鼠李糖甙,铃兰毒苷 |
NF-κB; P-gp; PPAR | DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB |
Convallatoxin 是从铃兰分离得到的一种强心苷。它是 P-糖蛋白底物,并识别 Val982 是参与其转运的重要氨基酸。它是配体诱导的 MOR 胞吞作用的增强剂,通过激活PPARγ和抑制NF-κB 改善结肠炎,具有抗炎和抗增殖特性。 | |||
T4879 |
12-Hydroxydodecanoic acid
12-hydroxylauric acid,12-羟基月桂酸 |
Others; Endogenous Metabolite | Metabolism; Others |
12-Hydroxydodecanoic acid (12-hydroxylauric acid) 是内源性代谢产物的一种。 | |||
T19302 |
D(-)-2-Aminobutyric acid
|
Endogenous Metabolite | Metabolism |
D(-)-2-Aminobutyric acid 是一种 D-氨基酸氧化酶的底物。 | |||
T12540 |
Pristinamycin IA
Mikamycin IA,普利霉素IA,Mikamycin B |
Others; Antibiotic; P-gp | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others |
Pristinamycin IA (Mikamycin B) 是 P-糖蛋白的底物,也是一种环肽类大环内酯抗生素。 | |||
T4891 |
Sodium phenylpyruvate
苯丙酮酸钠,Phenylpyruvic acid, sodium salt |
Others | Others |
Sodium phenylpyruvate (Phenylpyruvic acid, sodium salt) 是phenylpyruvate decarboxylase 和phenylpyruvate tautomerase 互变异构酶的底物。 | |||
T8086 |
Decyl aldehyde
|
Others; Endogenous Metabolite | Metabolism; Others |
Decyl aldehyde 是细菌荧光素酶底物,是十碳醛。 | |||
T10147 |
4-Hydroxymephenytoin
(+/-)-4'-Hydroxymephenytoin |
Others; Drug Metabolite | Metabolism; Others |
4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) 是抗癫痫药 mephenytoin 的代谢产物。Mephenytoin 是 CYP2C19的配体。 | |||
T4755 |
2,3-Diaminopropanoic acid hydrochloride
DL-2,3-Diaminopropionic acid monohydroch,3-Amino-DL-alanine monohydrochloride,DL-2,3-二胺基丙酸盐酸盐 |
Others; Endogenous Metabolite | Metabolism; Others |
2,3-Diaminopropanoic acid hydrochloride (3-Amino-DL-alanine monohydrochloride) 是内源性代谢产物的一种。 | |||
T4086 |
Glycyl-L-leucine
甘氨酰-L-亮氨酸,Gly-Leu |
Others | Others |
Glycyl-L-leucine (Gly-Leu) 是一种可用作糖基亮氨酸二肽酶底物的二肽。 | |||
T7970 |
7-Ethoxycoumarin
|
Others | Others |
7-Ethoxycoumarin 是细胞色素 P450(CYP) 的底物,现已被应用于多种 CYP 的功能表征。 | |||
T0846 |
L-Carnitine
L(-)-Carnitine,Levocarnitine,左旋肉碱 |
Endogenous Metabolite; Fatty Acid Synthase | Metabolism |
L-Carnitine (L(-)-Carnitine) 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。 | |||
TQ0217 |
Gomisin G
戈米辛G,戈米辛 G |
P450; HIV Protease | Metabolism; Microbiology/Virology; Proteases/Proteasome |
Gomisin G 是一种有抗HIV 活性的天然产物。 | |||
TN2107 |
Protoescigenin
|
Others | Others |
Protoescigenin 来自七叶树皂甙混合物,可用作用于选择性保护的探索性化学的底物。 | |||
T0588 |
D-(-)-Arabinose
D-阿拉伯糖,D(-)-Arabinose,D-arabinose |
Others | Others |
D-(-)-Arabinose 是一种单糖,对秀丽隐杆线虫有较强的生长抑制作用(IC50:7.5 mM)。 | |||
T4972 |
2'-Deoxycytidine-5'-diphosphate trisodium
dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐 |
Endogenous Metabolite | Metabolism |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。 | |||
T37635 |
2'-Deoxyadenosine-5'-triphosphate trisodium
dATP trisodium |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) 是一种核苷酸,是 DNA 聚合酶的底物,在细胞中用于 DNA 合成或复制。 | |||
T38475 |
2,6-Dimethylpyrazine
|
Others | Others |
2,6-Dimethylpyrazine 是食品工业中不可缺少的调味添加剂,也是生产降糖和抗脂解化合物的重要底物。 | |||
TN1328 |
7-Amino-4-methylcoumarin-3-acetic acid
7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin |
Others | Others |
7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) 是荧光蛋白质标记剂,能够被紫外光(350 nm) 激活,可在蓝色区域 (440-460 nm) 发光。 | |||
T3756 |
Allitol
Allodulcit,蒜糖醇,Allodulcitol,d-allitol |
Others | Others |
Allitol (d-allitol) 是一种罕见的可作为甜味剂天然多元醇。它是制备 azasugars 的重要中间体,可用于制备抗癌症、糖尿病及包括艾滋病在内的病毒感染的药物。 | |||
T3313 |
D-Luciferin
Firefly luciferin,D-萤光素,D-荧光素,D-(-)-Luciferin |
Others | Others |
D-Luciferin (D-(-)-Luciferin) 是一种萤光素酶的底物,能够催化生物发光昆虫产生典型的黄绿光。 | |||
T4731 |
2'-Deoxycytidine-5'-monophosphoric acid
dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate |
Others; Endogenous Metabolite | Metabolism; Others |
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) 被用作尿苷单磷酸(UMP)或胞苷单磷酸(CMP)激酶的底物,形成 dCDP,在磷酸化成 dCTP 后支持 DNA 的生物合成。 | |||
T4929 |
L-2-Phosphoglyceric acid
L-GLYCERATE 3-PHOSPHATE 二钠盐,L-2-Phosphoglyceric acid disodium salt h |
Others; Endogenous Metabolite | Metabolism; Others |
L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) 是内源性代谢产物的一种。 | |||
T60237 |
L-Cysteine S-sulfate
S-Sulfo-L-cysteine |
NMDAR | Neuroscience |
L-Cysteine S-sulfate (S-Sulfo-L-cysteine) 是有效的 N-methyl-d-aspartate (NMDA) 谷氨酸受体激动剂。L-Cysteine S-sulfate 是胱氨酸裂解酶的底物。 | |||
T0657 |
Veratryl alcohol
3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇 |
Others | Others |
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) 是木质素降解真菌的次级代谢产物,通常作为非酚性底物测定木质素分解活性。 | |||
T5578 |
L-Gulono-1,4-lactone
|
Others; Endogenous Metabolite | Metabolism; Others |
L-Gulono-1,4-lactone 是一种 L-古洛糖酸-γ-内酯氧化还原酶的作用底物,该酶能促进维生素 C 合成的末步。它是动物、植物和一些原生生物中维生素 C 的直接前体。 | |||
T4829 |
3-Hydroxyphenylacetic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
3-Hydroxyphenylacetic acid 是内源性代谢产物的一种。 | |||
T4702 |
(3-Carboxypropyl)trimethylammonium chloride
γ-Butyrobetaine hydrochloride,(3-羧丙基)三甲基氯化铵,(3-Carboxypropyl)trimethylammonium chlor |
Endogenous Metabolite | Metabolism |
(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) 一种血管病变性中间代谢物,是由肠道微生物代谢产生,这些微生物以红肉中的肉碱为食。 | |||
T3949 |
Myristic acid
肉豆蔻酸,Crodacid,Tetradecanoic acid,n-Tetradecanoic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Myristic acid (Crodacid) 是饱和的 14 碳脂肪酸,存在于大多数动物、植物的脂肪中,特别是乳脂,椰子油,棕榈油和肉豆蔻油。 | |||
T4779 |
4-Methylcatechol
p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene |
Others; Endogenous Metabolite | Metabolism; Others |
4-Methylcatechol (3,4-Dihydroxytoluene) 是 p-toluate 的代谢物,它是 Catechol 2,3-Dioxygenase 的自杀性底物抑制剂。 | |||
T8078 |
Gamma-decalactone
Decan-4-olide,γ-Decalactone,丙位癸内酯 |
Others | Others |
Gamma-decalactone (Decan-4-olide) 是一种具有果味桃子味的食品添加剂。蓖麻油酸 (12-羟基-十八烷基-9-烯酸) 常作为 γ-Decalactone 的生产过程中的底物。 | |||
T8072 |
S-Methyl-L-cysteine
S-甲基-L-半胱氨酸,S-Methylcysteine |
Antioxidant; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
S-Methyl-L-cysteine (S-Methylcysteine) 是一种催化抗氧化系统中甲硫氨酸硫氧化物还原酶 A 的作用底物,是一种天然产物,具有抗氧化、神经保护及减肥的功效。 | |||
T6808 |
Coelenterazine
Oplophorus luciferin,Coelenteramine,腔肠素 |
Others | Others |
Coelenterazine (Coelenteramine) 是一种 apoaequorin 和 Renilla 荧光素酶的发光酶底物。它是超氧阴离子敏感化学发光探针,可用于检测过氧亚硝酸盐的化学发光。其中 Renilla 荧光素酶和底物 coelenterazine 被用作生物发光共振能量转移中检测蛋白质-蛋白质相互作用的生物发光供体。 | |||
T13655 |
DL-Norepinephrine hydrochloride
去甲肾上腺素盐酸盐,Lys,DL-lysine |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
DL-Norepinephrine hydrochloride (DL-lysine) 是一种靶向α1 adrenoceptor 和β1 adrenoceptor 的神经递质,可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。 | |||
T4739 |
Sodium creatine phosphate dibasic tetrahydrate
磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) 主要存在于脊椎动物的骨骼肌中,是测定肌酸激酶的底物,能够用于骨骼肌收缩过程中 ATP 的再生。 | |||
T4928 |
L-Kynurenine
L-犬尿氨酸,(S)-Kynurenine |
AhR; Aryl Hydrocarbon Receptor; Endogenous Metabolite | Immunology/Inflammation; Metabolism |
L-Kynurenine ((S)-Kynurenine) 是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。 | |||
TN7244 |
Egg PG
Phosphatidylglycerols(egg) |
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Egg PG(Phosphatidylglycerols(egg)) 是一种食物和生物组织的主要磷脂酰甘油之一,常存在于细菌和动物细胞的膜中,可作为 sPMCA,反应中的阴离子磷脂底物。 | |||
T3095 |
Tyramine
4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine |
MAO; Endogenous Metabolite | Metabolism; Neuroscience |
Tyramine (Uteramine) 是天然存在于体内或某些食物中的氨基酸。Tyramine 有助于调节血压。 | |||
T10148 |
4-Hydroxynonenal
4-羟基壬烯醛,4-HNE |
Dehydrogenase; Endogenous Metabolite | Metabolism |
4-Hydroxynonenal (4-HNE) 是一种 α,β 不饱和羟基烯醛,可作为氧化/亚硝化应激生物标志物。它是ALDH2的底物和抑制剂。它可以调节许多信号传导过程,主要是通过与蛋白质,核酸和膜脂质中具有亲核官能团的共价加合物形成的。它通过线粒体在癌症中起重要作用。 | |||
T4897 |
Inosine-5'-triphosphate trisodium salt
ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt |
Others; Endogenous Metabolite | Metabolism; Others |
Inosine-5'-triphosphate trisodium salt (ITP) 是三磷酸核苷,能够作为 ATPases 和 GTPases 的底物。 | |||
T10938 |
D-Kynurenine
D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 |
GPR; AhR; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism |
D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。 | |||
T2P2919 |
(2S,3R,4S)-4-Hydroxyisoleucine
(4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine |
PI3K | PI3K/Akt/mTOR signaling |
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分,具有抗糖尿病、抗糖尿病肾病的作用。 | |||
T3950 |
Tridecanoic acid
n-Tridecoic Acid,n-Tridecanoic Acid,十三酸,Tridecylic Acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Tridecanoic acid (Tridecylic Acid) 是一种存在于乳制品中的 13 碳饱和脂肪酸,也是正十六烷厌氧生物降解的产物。 它是磷脂酶 A2 的底物,可作为抗粘剂和抗生物膜剂,用于研究细菌感染。它抑制大肠杆菌的持久性和生物膜形成。 | |||
T7998 |
1,7-Diaminoheptane
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Others | Others |
1,7-Diaminoheptane 是一种脂族胺家族的化合物。它可用于合成肽、拟肽和其他化合物,也被用作酶反应中的底物,金属配合物中的配体,以及有机合成中的试剂。 | |||
T5216 |
Calcium L-Threonate
L-苏糖酸钙,L-Threonic acid Calcium Salt |
Others; Endogenous Metabolite | Metabolism; Others |
Calcium L-Threonate (L-Threonic acid Calcium Saltr) 是一种抗骨质疏松症,能够刺激抗坏血酸的吸收,常用于钙补充剂。 | |||
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