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Search Results for " myocardial ischemia "

42

抑制剂 & 化合物

10

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9765	TJ-M2010-5	MyD88	Immunology/Inflammation
	TJ-M2010-5 是一种 MyD88 抑制剂，可与 TIR 结构域结合以干扰其同源二聚化并抑制 MyD88 信号传导。 TJ-M2010-5 可用于心肌缺血/再灌注损伤研究。
T1101	Minocycline hydrochloride Minocycline HCl,盐酸米诺环素,美满霉素	HIF/HIF Prolyl-Hydroxylase; Antibacterial; Antibiotic	Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Minocycline hydrochloride (Minocycline HCl) 是四环素抗生素，具有出色的吸收和组织渗透性，可用于多种细菌感染以及痤疮的治疗。米诺环素可导致在开始治疗后 1 至 3 个月内发生的急性肝炎样综合征或通常在长期治疗后具有自身免疫特征的更隐匿的慢性肝炎。
T1046	Mexiletine hydrochloride KOE-1173 (hydrochloride),Mexiletine HCl,KO1173,盐酸美西律	AhR; Sodium Channel	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
	Mexiletine hydrochloride (KOE-1173 hydrochloride) 是一种电压门控钠通道阻滞剂，是 IB 类抗心律失常药。 Mexiletine hydrochloride 通过抑制心肌细胞内钠电流，从而降低心脏动作电位（0相）上升速率，并且降低浦肯野纤维的自律性而发挥抗心律失常作用。
T3230	NLRP3-IN-2 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺,NLRP3 Inflammasome Inhibitor I	NOD-like Receptor (NLR); NOD	Immunology/Inflammation; NF-κB
	NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide) 是一种能够合成格列本脲的中间物，对心肌细胞中NLRP3炎症小体的形成具有抑制作用，在小鼠心肌缺血/再灌注后限制梗死面积，且对代谢无影响。
T34648	Sinitrodil ITF296,ITF-296,ITF 296	Guanylate cyclase	GPCR/G Protein
	Sinitrodil (ITF-296) 是一种鸟苷酸环化酶兴奋剂，可用于治疗心肌缺血和心绞痛。
T83977	BIIB 722 Mesylate	Sodium Channel	Membrane transporter/Ion channel
	BIIB 722 Mesylate 是一种选择性钠氢交换抑制剂，具有心脏保护作用，可用于研究心肌缺血和心肌梗死。
T8687	diaminohydroxypropanetetraacetic acid	Others	Others
	diaminohydroxypropanetetraacetic acid 已被研究用于治疗血管疾病、冠状动脉疾病、心肌缺血、冠状动脉再狭窄和冠状动脉疾病等。
T68088	Iodofiltic acid
	Iodofiltic acid 可用于辅助治疗急性冠脉综合征（Zeus-ACS），可成像以检测心肌缺血。
T61933	MK-0159	CD38	Immunology/Inflammation
	MK-0159 是一种可口服且具有高效性的 CD38 抑制剂，具有心肌损伤保护作，可用于研究心脏缺血和再灌注损伤。
T9180	LUF6096 CF-602	Adenosine Receptor	GPCR/G Protein; Neuroscience
	LUF6096 (CF-602) 是一种有效的腺苷 A3 受体 (adenosine A3 receptor) 变构增强剂。LUF6096 对任何腺苷受体显示出低正构亲和力。LUF6096 在心肌缺血/再灌注损伤中显示出保护作用。
T20563	PD-166793 PD-166793-0000,PD 166793,PD166793	MMP	Proteases/Proteasome
	PD-166793是一种具有口服活性、有效性和选择性的 MMP 抑制剂，对 MMP-2，MMP-3 和 MMP-13 具有抑制作用。PD-166793 在大鼠心力衰竭模型中改善心肌缺血和再灌注损伤。
T23356	Linsidomine hydrochloride SIN-1 chloride	Others	Others
	Linsidomine hydrochloride (SIN-1 chloride) 是莫西多明的代谢产物，具有舒张血管、抑制血小板聚集和抗心绞痛的活性。在心肌缺血-再灌注模型中，Linsidomine hydrochloride 减少心肌坏死和再灌注诱导的内皮功能障碍，与海绵体的作用机制涉及一氧化氮的释放有关。
T37379	Protectin D1 Neuroprotectin D1,NPD1	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Protectin D1 (Neuroprotectin D1) 是神经细胞产生的神经保护素，是一种潜在的心脏保护剂。Protectin D1 通过调节 PI3K/AKT 信号通路缓解心肌缺血/再灌注损伤，抑制咪喹莫特诱导的银屑病样皮肤炎症。
T6633	Ranolazine 雷诺嗪,CVT 303,Ranexa,RS 43285-003	Calcium Channel; Sodium Channel	Membrane transporter/Ion channel; Metabolism
	Ranolazine (RS 43285-003) 具有抗心绞痛和抗缺血的功效，通过抑制内向钠电流的后期作用 (对INa 和IKr 的IC50值分别为 6 μM 和 12 μM) 发挥作用，而不会影响心率或血压。Ranolazine 还是脂肪酸氧化 (FAO) 的部分抑制剂。
T36569	KR-32568	Sodium Channel	Membrane transporter/Ion channel
	KR-32568是一种钠/氢交换器1（NHE-1）抑制剂（IC50：230 nM）。KR-32568具有强大的心脏保护作用。当使用浓度为10μM 时，它能在离体的缺血大鼠心脏模型中恢复心脏收缩功能。KR-32568（0.3mg/kg）在缺血和再灌注损伤的大鼠模型中减少了心肌梗死的大小。
T31117	CVT-2513 RS88681,RS 88681,CVT2513,CVT 2513,RS-88681
	CVT-2513 is a metabolite of Renolazine, which has anti-myocardial ischemia effect.
T31116	CVT-2512 RS 88640,RS-88640,CVT 2512,UNII-04210SF62M
	CVT-2512 is a metabolite of Renolazine, which has anti-myocardial ischemia effect.
T68878	L-2286
	L-2286 is a novel PARP inhibitor. L-2286 exerted significant protective effect against ischemia-reperfusion-induced myocardial injury in both experimental models. More importantly, L-2286 facilitated the ischemia-reperfusion-induced activation of Akt, extracellular signal-regulated kinase, and p38-MAPK in both isolated hearts and in vivo cardiac injury.
T37697	D-GsMTx4 D-GsMTx4
	TRPC1/6 and Piezo2 inhibitor. Exhibits same effect as L-enantiomer, GsMTx4 (Cat. No. 4912) on TRPC channels. Inhibits mechanosensitive currents by ~70%. Protects against myocardial infarction in mouse ischemia/reperfusion model. Resistant to proteolytic digestion.
T30512	BMS-284640 UNII-XP87V064PV,CHEMBL51879,XP87V064PV
	BMS-284640 is a Na(+)/H(+) exchange agent (NHE) inhibitor that has provided substantial protection in various animal models of myocardial ischemia (MI) and reperfusion in preclinical studies.
T78019	Nangibotide TFA LR12 TFA
	Nangibotide TFA为TREM-1受体抑制剂，调控先天免疫反应。该化合物能降低啮齿动物心肌缺血再灌注模型的系统性及局部炎症。
T72281	Caspase-9 Inhibitor III Ac-LEHD-cmk
	Caspase-9 Inhibitor III (Ac-LEHD-cmk) 是一种 caspase-9抑制剂。Caspase-9 Inhibitor III 对局部缺血-重新灌注诱导的心肌损伤表现出保护作用。
T63649	Ned-K
	Ned-K 是一种烟酸腺嘌呤二核苷酸磷酸 (NAADP) 拮抗剂，对心肌缺血和再灌注 (sIR) 诱导的钙振荡表现出抑制作用。
T36223	MitoA
	MitoA is a ratiometric mass spectrometry probe that can be used for assessing changes in H2S within mitochondria in vivo. MitoA contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its aryl azide moiety selectively reacts with H2S to produce an amine product, MitoN. Quantifying the MitoN/MitoA ratio by LC-MS/MS reflects the mitochondrial matrix H2S concentration. In a mouse model of acute myocardial infarction with MitoA administered prior to ischem...
T73661	Delcasertib hydrochloride
	Delcasertib (KAI-9803) hydrochloride 是有效，选择性的 δ 蛋白激酶 C (δPKC) 抑制剂。Delcasertib (KAI-9803) hydrochloride 可改善急性心肌梗死动物模型的缺血再灌注损伤。
T81707	Nangibotide LR12
	Nangibotide为TREM-1受体抑制剂，具有调节先天免疫反应的作用。在啮齿动物心肌缺血再灌注模型中，Nangibotide能有效减轻全身及原位的炎症反应。
T77163	Pexelizumab
	Pexelizumab (h5G1.1-SC)为一种针对C5补体成分的人源化单克隆抗体。该化合物可抑制凋亡(apoptosis)和白细胞浸润，常用于研究脑缺血再灌注损伤和心肌梗死。
T27302	Falipamil AQ-A 39,AQ-A-39,AQ-A39
	Falipamil is a verapamil derivative and a calcium channel antagonist. Falipamil exerts antitachycardic effects by a direct action on the sinus node. Falipamil decreases HR at exercise in normal subjects and may exert antianginal effects in patients with m
T41251	Taprostene
	Taprostene (CG-4203) 是一种合成的、化学稳定的前列环素 (PGI2) 类似物。Taprostene 对猫急性心肌缺血再灌注后内皮和心肌有保护作用。Taprostene 增强细胞保护作用，同时减少不必要的血液动力学影响。
T68397	Xamoterol fumarate
	Xamoterol fumarate is a selective beta-1-adrenergic partial agonist. Because it is a partial agonist, it acts as an agonist when sympathetic activity is low and as an antagonist when sympathetic activity is high. It reduces myocardial ischemia and improves ventricular function in patients with mild to moderate heart failure. In patients with severe heart failure it has been shown to produce benefits in systolic and diastolic function.
T35871	Bopindolol (malonate)
	Bopindolol is a non-selective β-adrenergic receptor antagonist. In vivo, bopindolol decreases heart rate and blood pressure and attenuates ischemia-induced myocardial acidosis in dogs. Formulations containing bopindolol have been used to treat essential and renovascular hypertension.
T78887	ROS-IN-2	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	ROS-IN-2 (compound 85) 为次狼烷三萜衍生物，具有抑制细胞内过量ROS及其他氧化应激源生成的作用，从而保护线粒体避免受损。该化合物在心肌缺血/再灌注（MI/R）损伤研究中具有潜在应用价值。
T83043	Anti-MI/R injury agent 1
	Anti-MI/R injury agent 1 (compound 18) 是一种口服有效的人参三醇衍生物，专用于抗心肌缺血/再灌注 (MI/R) 损伤。该化合物能增强经氧-葡萄糖剥夺和再灌注 (OGD/R) 诱导心肌细胞损伤模型中的细胞活力，显着缩小大鼠心肌梗死面积，减少循环心肌肌钙蛋白 I (cTnI) 的释放，并减轻心脏组织损害。
T21989	SSR 69071
	SSR69071 是一种有效的，具有口服活性的选择性中性粒细胞弹性蛋白酶 (neutrophil elastase) 抑制剂。SSR69071 对人弹性蛋白酶 (Ki=0.0168 nM) 的亲和力高于对大鼠 (Ki=3 nM)、小鼠 (Ki=1.8 nM) 和兔 (Ki=58 nM) 弹性蛋白酶。SSR69071 减少缺血再灌注损伤后的心肌梗死面积。SSR69071 还具有治疗慢性阻塞性肺病、哮喘、肺气肿、囊性纤维化和多种炎症性疾病的潜力。
T83880	C18 Ceramide-1-phosphate (d18:1/18:0) ammonium Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate
	C18 Ceramide-1-phosphate (d18:1/18:0) 是一种在鼠皮肤中发现的长链ceramide-1-phosphate。它能在0.5至5 µM的浓度范围内促进分离的小鼠骨髓来源的多能间充质细胞和人脐静脉内皮细胞（HUVECs）的迁移。与胰腺癌干细胞相比，CFPAC-1胰管腺癌细胞中C18 Ceramide-1-phosphate (d18:1/18:0)的水平有所增加。在Langendorff分离的灌流小鼠心脏的离体缺血模型中，心肌中C18 ceramide-1-phosphate (d18:1/18:0)的水平有所增加。
T71402	Nicorandil-d4
	Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...
T36004	1-O-Hexadecyl-sn-glycerol 1-O-Hexadecyl-sn-glycerol,(S)-(+)-Chimyl Alcohol,α-Chimyl Alcohol
	1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury. [2].Maulik, N., Tosaki, A., Engelman, R.M., et al. Myocardial salvage by chimyl al...
T36722	Deltorphin II (trifluoroacetate salt)
	Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid...
T37697L	D-GsMTx4 TFA	TRP/TRPV Channel; Piezo Channel	Membrane transporter/Ion channel
	D-GsMTx4 TFA 是一种具有选择性的蜘蛛毒液肽，是一种TRPC1 / 6和Piezo2抑制剂，可抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透的机械敏感性通道（MSCs），阻断阳离子选择性的拉伸激活通道（SAC），减弱溶血磷脂酰胆碱（LPC）诱导的星形胶质细胞毒性和小胶质细胞反应性。D-GsMTx4 TFA 在小鼠缺血/再灌注模型中预防心肌梗死，可用于鉴定兴奋性 MSC 在正常生理学和病理学中的作用。
T79446	INF200	NOD-like Receptor (NLR)	Immunology/Inflammation
	INF200（compound 5）是一种磺酰脲衍生的抑制剂，既能抑制NLRP3也能抑制NLRP3介导的焦亡(pyroptosis)。在HFD诱导的大鼠模型上，INF200对心脏代谢表现出有益效果，并且在(10 μM)浓度下减少了人巨噬细胞中IL-1β的释放，表现出抗炎特性。它还能改善血糖控制和脂质水平，降低全身炎症和心功能障碍的标志物（尤其是BNP水平）。此外，INF200在血流动力学评估中还可提升心肌损伤后的缺血/再灌注损伤(IRI)恢复。
T35463	(±)14(15)-EET (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
	(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) induced by oxidized LDL in primary rat pulmonary artery endothelial cells (RPAECs) when used at a concentration of 1 μM.[3] (±)14(15)-EET induces dilation of preconstricted isolated canine coronary arterioles (EC50 = 0.2 pM).[4] It reduces myocardial infarct size as a percentage o...
T37297	Ru360
	Ru360, an oxygen-bridged dinuclear ruthenium amine complex, is a selective mitochondrial calcium uptake inhibitor. Ru360 potently inhibits Ca2+ uptake into mitochondria with an IC50 of 0.184 nM. Ru360 binds to mitochondria with high affinity (Kd of 0.34 nM). Ru360 has antiarrhythmic and cardioprotective effects[1][2]. Ru360 permeates slowly into the cell, and specifically inhibits mitochondrial calcium uptake in intact cardiomyocytes and in isolated heart. 1 μm Ru360 is taken up by myocardial ce...

化合物

Cat.No: T9765

Target: MyD88

Minocycline hydrochloride

Cat.No: T1101

Synonym: Minocycline HCl,盐酸米诺环素,美满霉素

Target: HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Mexiletine hydrochloride

Cat.No: T1046

Synonym: KOE-1173 (hydrochloride),Mexiletine HCl,KO1173,盐酸美西律

Target: AhR, Sodium Channel

Cat.No: T3230

Synonym: 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺,NLRP3 Inflammasome Inhibitor I

Target: NOD-like Receptor (NLR), NOD

Cat.No: T34648

Synonym: ITF296,ITF-296,ITF 296

Target: Guanylate cyclase

BIIB 722 Mesylate

Cat.No: T83977

Target: Sodium Channel

diaminohydroxypropanetetraacetic acid

Cat.No: T8687

Target: Others

Iodofiltic acid

Cat.No: T68088

Cat.No: T61933

Target: CD38

Cat.No: T9180

Synonym: CF-602

Target: Adenosine Receptor

Cat.No: T20563

Synonym: PD-166793-0000,PD 166793,PD166793

Target: MMP

Linsidomine hydrochloride

Cat.No: T23356

Synonym: SIN-1 chloride

Target: Others

Cat.No: T37379

Synonym: Neuroprotectin D1,NPD1

Target: Akt, PI3K

Cat.No: T6633

Synonym: 雷诺嗪,CVT 303,Ranexa,RS 43285-003

Target: Calcium Channel, Sodium Channel

Cat.No: T36569

Target: Sodium Channel

Cat.No: T31117

Synonym: RS88681,RS 88681,CVT2513,CVT 2513,RS-88681

Cat.No: T31116

Synonym: RS 88640,RS-88640,CVT 2512,UNII-04210SF62M

Cat.No: T68878

Cat.No: T37697

Synonym: D-GsMTx4

Cat.No: T30512

Synonym: UNII-XP87V064PV,CHEMBL51879,XP87V064PV

Nangibotide TFA

Cat.No: T78019

Synonym: LR12 TFA

Caspase-9 Inhibitor III

Cat.No: T72281

Synonym: Ac-LEHD-cmk

Cat.No: T63649

Cat.No: T36223

Delcasertib hydrochloride

Cat.No: T73661

Cat.No: T81707

Synonym: LR12

Cat.No: T77163

Cat.No: T27302

Synonym: AQ-A 39,AQ-A-39,AQ-A39

Cat.No: T41251

Xamoterol fumarate

Cat.No: T68397

Bopindolol (malonate)

Cat.No: T35871

Cat.No: T78887

Target: Reactive Oxygen Species

Anti-MI/R injury agent 1

Cat.No: T83043

Cat.No: T21989

C18 Ceramide-1-phosphate (d18:1/18:0) ammonium

Cat.No: T83880

Synonym: Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate

Cat.No: T71402

1-O-Hexadecyl-sn-glycerol

Cat.No: T36004

Synonym: 1-O-Hexadecyl-sn-glycerol,(S)-(+)-Chimyl Alcohol,α-Chimyl Alcohol

Deltorphin II (trifluoroacetate salt)

Cat.No: T36722

Cat.No: T37697L

Target: TRP/TRPV Channel, Piezo Channel

Cat.No: T79446

Target: NOD-like Receptor (NLR)

Cat.No: T35463

Synonym: (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET

Cat.No: T37297

Cat. No.	Product Name	Target	Signaling Pathways
TN6490	Regaloside C	Others	Others
	Regaloside C 是一种从百合属的中分离出来的甘油葡糖苷，具有抗炎作用。
T3S0289	Araloside X	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi
T2S0500	Ilexsaponin A 毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1	Others	Others
	Ilexsaponin A (Ilexsaponin A1)1 是分离自冬凌草的根中，利用抗凋亡途径减轻缺血再灌注引起的心肌损伤。它能够减少心肌梗塞的大小，减少 LDH，AST 和 CK-MB 的血清水平，促进细胞活力并抑制缺氧/复氧心肌细胞的凋亡。
T5S2178	Fargesin 辛夷脂素,(+/-)-Fargesin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fargesin ((+/-)-Fargesin) 是一种活性新木脂素，从木兰植物中分离得到，具有抗高血压和抗炎活性。
T3920	Pseudoginsenoside F11 Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11	Others; Endogenous Metabolite	Metabolism; Others
	Pseudoginsenoside F11 (Ginsenoside A1) 从人参根和叶中分离得到。PF11在一系列心血管和中枢神经系统疾病中具有广泛的保护作用。
T5S1632	Barlerin 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01	VEGFR; TNF; NF-κB; Akt; Caspase	Angiogenesis; Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Barlerin (8-O-Acetylshanzhiside methyl ester) 是一种环孢菌素葡萄糖苷，从中国西藏民间药用植物中分离得到，能够抑制NF-κB 活性。
T4518	Licochalcone D	ERK; NF-κB	MAPK; NF-κB
	Licochalcone D 是一种 NF-κB p65的有效抑制剂，是一种存在于 Glycyrrhiza inflate 中的黄酮类化合物，具有抗氧化、抗炎、抗癌等作用。
TN1101	20(R)-Notoginsenoside R2 R-三七皂苷R2,20(R)-三七皂苷R	Others	Others
	20(R)-Notoginsenoside R2 is a natural product with Promote blood circulation and improve myocardial ischemia
TN1431	Baohuoside VII 宝藿苷,宝藿苷VII	Others	Others
	Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Baohuoside VII in vivo exhibits significant anti
TN3914	Echinatine	ATPase; IL Receptor; TNF	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin can inhibit DNP-ATPase activity whil

天然产物

Cat.No: TN6490

Target: Others

Cat.No: T3S0289

Target: Calcium Channel

Cat.No: T2S0500

Synonym: 毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1

Target: Others

Cat.No: T5S2178

Synonym: 辛夷脂素,(+/-)-Fargesin

Target: Adrenergic Receptor

Pseudoginsenoside F11

Cat.No: T3920

Synonym: Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11

Target: Others, Endogenous Metabolite

Cat.No: T5S1632

Synonym: 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01

Target: VEGFR, TNF, NF-κB, Akt, Caspase

Cat.No: T4518

Target: ERK, NF-κB

20(R)-Notoginsenoside R2

Cat.No: TN1101

Synonym: R-三七皂苷R2,20(R)-三七皂苷R

Target: Others

Cat.No: TN1431

Synonym: 宝藿苷,宝藿苷VII

Target: Others

Cat.No: TN3914

Target: ATPase, IL Receptor, TNF

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