115
46
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0574 |
Diphenyl sulfide
二苯硫醚,Phenyl sulfide |
Others | Others |
Diphenyl sulfide (Phenyl sulfide) 用作农药、医药、染料的中间体 | |||
T37518 |
Diphenyl disulfide
Phenyl disulfide |
Apoptosis; BCL; Endogenous Metabolite | Apoptosis; Metabolism |
Diphenyl disulfide (Phenyl disulfide) 在乳腺癌细胞系中显示出抗癌活性。Diphenyl disulfide 通过Bax 蛋白水解活化和伴随的自噬来诱导并增强乳腺癌细胞的凋亡。Diphenyl disulfide 以剂量依赖性方式抑制细胞增殖和活力,并减少集落形成。Diphenyl disulfide 可用来治疗乳腺癌。 | |||
T0621 |
Diphenyl oxide
Oxydibenzene,Phenyl ether,二苯醚 |
Others | Others |
Diphenyl oxide (Oxydibenzene) 用于制造香料和染料。 | |||
T1348 |
Diphenyl phosphate
磷酸二苯酯,Phenyl hydrogen phosphate |
Others | Others |
Diphenyl phosphate (Phenyl hydrogen phosphate) 能够性别特异性的抑制斑马鱼的生长和能量代谢。 | |||
T18979 |
Diphenyl Blue
台盼蓝,Direct Blue 14 |
Others | Others |
Diphenyl Blue (Direct Blue 14) 是一种可用作偶氮染料组的参考染料。 | |||
T20932 |
Diphenyl cresyl phosphate
Monocresyl diphenyl phosphate,Diphenyl tolyl phosphate |
||
Diphenyl cresyl phosphate is a flame retardant, plasticizers, additives of gasoline, and lubricant. | |||
T20093 |
p-Phenylenediamine, N,N'-diphenyl-
NSC 761,NSC 5761,Flexamine G,NSC-5761,N,N'-二苯基-1,4-苯二胺,DPPD |
Others | Others |
p-Phenylenediamine, N,N'-diphenyl- (NSC-761) 是一种生物活性化学品。它已被用于预防羔羊维生素 E 缺乏症。 | |||
T9936 |
ZX-J-19J
N-(2,3-Diphenyl-6-quinoxalinyl)octanamide |
Others | Others |
ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide) 是 Cyclophilin J 的抑制剂,对肿瘤细胞生长有显着的抑制作用,与环孢素 A 相当,但比 5-氟尿嘧啶强得多。 | |||
T7336 |
ICA-121431
2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl |
Sodium Channel | Membrane transporter/Ion channel |
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) 是强效的、广谱的电压门控钠通道阻滞剂,对人 Nav1.1 和 Nav1.3 亚型具有等效选择性,IC50分别为 13 nM 和 23 nM。它对Nav1.2 的抑制作用较弱,IC50为240 nM,对 Nav1.4、Nav1.6、抗TTX 的人 Nav1.5、Nav1.8 通道表现出大于 1000 倍的选择性,IC50>10 μM。 | |||
T11093 |
DPPH
2,2-联苯基-1-苦基肼基,2,2-Diphenyl-1-picrylhydrazyl |
Others | Others |
DPPH (2,2-Diphenyl-1-picrylhydrazyl) 是一种稳定的自由基,可用于测量抗氧化剂的自由基清除活性。DPPH 中氮原子的奇数电子通过从抗氧化剂吸收氢原子而还原为相应的肼。通过 DPPH 方法可用于水性和非极性有机溶剂中,检查亲水性和亲脂性抗氧化剂。 | |||
T9324 |
1,5-diphenylpyrazole-3-carboxylic acid
1,5-二苯基-1H-吡唑-3-羧酸,1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL- |
Others | Others |
1,5-diphenylpyrazole-3-carboxylic acid (1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL-) 是植物生理上可耐受的盐基或任何所需的酯基。 | |||
T20356 |
2-Propanone, 1,1-diphenyl-
NSC-400472,NSC 400472,NSC400472 |
||
2-Propanone, 1,1-diphenyl- is an agent of biochemical. | |||
TNU0677 |
3,5-Diphenyl pyridine
|
||
Heterocyclic compounds-pyridine, | |||
T31515 |
Dipentyl sebacate
Sebacinsaeurediphenylester,Diphenyl-sebacinat,Decandisaeure-diphenylester,Sebacinsaeure-diphenylester |
||
Dipentyl sebacate is a biochemical. | |||
T31794 |
FireMaster 695
1,2-Bis(pentabromophenoxy)ethane,Decabromo diphenyl ethyl,Ethylene bis(pentabromophenoxide),Decabromodiphenoxyethane |
||
FireMaster 695 is a biochemical. | |||
T65609 | (S)-Diphenyl(pyrrolidin-2-yl)methanol | ||
(S)-Diphenyl(pyrrolidin-2-yl)methanol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65609,CAS号为 112068-01-6。 | |||
T66039 |
Boc-D-Ala(3,3-diphenyl)-OH
|
||
Boc-D-Ala(3,3-diphenyl)-OH 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66039,CAS号为 143060-31-5。 | |||
T65489 |
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
|
||
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is used as a probe for luminescent detection and quantitation of oxygen (absorption λmax=455 nm, luminescence λmax=613 nm). It is also used for fibre optic sensors. At the same time, Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used in studies on oxygen in skin and skin tumors as well as measurement of oxygen flux through the skin. | |||
T65141 |
1-(3,3-Diphenyl-N-methylpropylamino)-2-methyl-2-propanol
|
||
1-(3,3-Diphenyl-N-methylpropylamino)-2-methyl-2-propanol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65141,CAS号为 100442-33-9。 | |||
T66791 | 2,6-Bis[[(R)-2-[hydroxy(diphenyl)methyl]-1-pyrrolidinyl]methyl]-4-methylphenol | ||
2,6-Bis[[(R)-2-[hydroxy(diphenyl)methyl]-1-pyrrolidinyl]methyl]-4-methylphenol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T66791。 | |||
T64503 |
2,6-Bis((4S,5S)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl)pyridine
|
||
2,6-Bis((4S,5S)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl)pyridine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64503,CAS号为 1221973-02-9。 | |||
T67266 | N-[(1S,2S)-1,2-Diphenyl-2-(2-(4-methylbenzyloxy)ethylamino)-ethyl]-4-methylbenzene sulfonamide(chloro)ruthenium(II) | ||
N-[(1S,2S)-1,2-Diphenyl-2-(2-(4-methylbenzyloxy)ethylamino)-ethyl]-4-methylbenzene sulfonamide(chloro)ruthenium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67266,CAS号为 1384974-37-1。 | |||
T67324 | (1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide | ||
(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67324,CAS号为 900160-98-7。 | |||
T20253 |
N,N'-Diphenylguanidine
NSC 3272,NSC3272,NSC-3272,二苯胍 |
Others | Others |
N,N'-Diphenylguanidine (NSC-3272) 是一种生化剂。 | |||
T0560 |
3,3-Diphenylpropylamine
|
Others | Others |
3,3-Diphenylpropylamine 用于合成药物 Mepramidil | |||
T50052 |
1,2-diphenylpropan-2-amine
|
Others | Others |
1,2-diphenylpropan-2-amine 是Remacemide 的(S,R)-异构体单盐酸盐代谢产物。1,2-diphenylpropan-2-amine 具有抗惊厥作用。 | |||
T38240 |
2,6-Dichlorodiphenylamine
|
Antibacterial | Microbiology/Virology |
2,6-Dichlorodiphenylamine 是双氯芬酸钠的一种结构类似物,显示出抗白色念珠菌活性。2,6-Dichlorodiphenylamine 是非选择性抗炎剂,为COX 的抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50分别为 4 和 1.3 nM。 | |||
T7191 |
Diphenyleneiodonium chloride
二苯基氯化碘盐,DPI |
NOS; Reactive Oxygen Species; NADPH; TRP/TRPV Channel | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB |
Diphenyleneiodonium chloride (DPI) 是 NADPH 氧化酶抑制剂,也是 TRPA1激活剂,EC50为 1 - 3 μM 。它选择性抑制胞内活性氧。 | |||
T0623 |
Diphenylacetonitrile
二苯乙腈,Dipan,Diphenatrile |
Others | Others |
Diphenylacetonitrile (Dipan) 用作除草剂和工业中间体。 | |||
T4693 |
2-Aminoethyl diphenylborinate
2-Aminoethoxydiphenyl borate,二苯基酸,2-APB |
Calcium Channel; TRP/TRPV Channel | Membrane transporter/Ion channel; Metabolism |
2-Aminoethyl diphenylborinate (2-APB) 是细胞通透性的 IP3R 和 TRP 通道抑制剂,还抑制 store-operated Ca2+(SOC)通道。 | |||
T3193 |
Pimelic diphenylamide 106
Histone Deacetylase Inhibitor VII,TC-H 106,RGFA-8 |
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Pimelic diphenylamide 106 (RGFA-8) 是一种缓慢和紧密结合的I 类HDAC 抑制剂,对HDAC1、 2和3的IC50值分别150、760和370 nM。 | |||
T0544 |
Dichlorodiphenylmethane
二氯二苯甲烷,Benzophenone dichloride |
Others | Others |
Dichlorodiphenylmethane (Benzophenone dichloride) 用作医药中间体。 | |||
T21444 |
Diphenylcyclopropenone
DPCP,Diphencyprone,二苯基环丙烯酮 |
Others | Others |
Diphenylcyclopropenone (DPCP) 是局部免疫调节剂,可用于研究斑秃。 | |||
T18978 |
Diphenylterazine
DTZ |
Others | Others |
Diphenylterazine (DTZ) 是一种生物发光剂。它本身仅产生很少的背景,使其具有极好的信噪比。 | |||
T2716 |
1,3-Diphenylurea
|
Epoxide Hydrolase | Metabolism |
1,3-Diphenylurea 与环氧化物水解酶活性有关。 | |||
T67235 | (S)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(diphenylphosphino)ethyl]ferrocene | ||
(S)-1-[(S)-tert-Butylphosphinoyl]-2-[(S)-1-(diphenylphosphino)ethyl]ferrocene 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67235。 | |||
T67269 | (S)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethoxy]phthalazine | ||
(S)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethoxy]phthalazine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67269。 | |||
T67274 | (R)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethoxy]phthalazine | ||
(R)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethoxy]phthalazine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67274。 | |||
T67390 | R-(+)-6,6'-Bis(diphenylphosphino)-2,2',3,3'-tetrahydro-5,5'-bi-1,4-benzodioxin | ||
R-(+)-6,6'-Bis(diphenylphosphino)-2,2',3,3'-tetrahydro-5,5'-bi-1,4-benzodioxin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67390。 | |||
T67391 | (15aR)-1,15-Bis(diphenylphosphino)-7,8,9,10-tetrahydro-6H-dibenzo[b,d][1,6]dioxacycloundecine | ||
(15aR)-1,15-Bis(diphenylphosphino)-7,8,9,10-tetrahydro-6H-dibenzo[b,d][1,6]dioxacycloundecine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67391。 | |||
T67395 | (12aR)-1,12-Bis(diphenylphosphino)-6,7-dihydrodibenzo[e,g][1,4]dioxocine | ||
(12aR)-1,12-Bis(diphenylphosphino)-6,7-dihydrodibenzo[e,g][1,4]dioxocine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67395。 | |||
T78440 |
1,6-Diphenylhexa-1,3,5-triene
|
||
1,6-Diphenylhexa-1,3,5-triene是荧光探针,具备检测分子相互作用与结构变化的能力。 | |||
T65888 |
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid
|
||
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65888,CAS号为 189937-46-0。 | |||
T83423 |
1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine
|
||
1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine 是一种荧光探针,其极性磷脂酰乙醇胺头基适用于测定脂蛋白与血浆表面脂质的氧化。 | |||
T78414 |
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide
|
||
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide 是一种点击化学反应型并可酸裂解的 Biotin-picolyl azide 衍生物。它作为细胞表面糖蛋白的捕获手柄,适用于蛋白质的标记工作。 | |||
T64928 |
tert-Butyl 2-((diphenylmethylene)amino)acetate
|
||
tert-Butyl 2-((diphenylmethylene)amino)acetate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64928,CAS号为 81477-94-3。 | |||
T20360 |
Chlorodiphenylmethane
AI311230,AI3-11230,AI3 11230 |
||
Chlorodiphenylmethane is an organic compound. It has two phenyl rings. | |||
T20295 |
Diphenylacetamide
NSC3133,NSC 3133,NSC-3133 |
||
Diphenylacetamide is an agent of biochemical. | |||
T66243 |
Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
|
||
Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66243,CAS号为 178306-47-3。 | |||
T19519 |
Pimelic Diphenylamide 106 analog
RGFA-8 analog,TC-H 106 analog |
Others | Others |
Pimelic Diphenylamide 106 analog is an Pimelic Diphenylamide 106 analog . |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN7144 |
3,4-Diphenyl-5H-furan-2-one
3,4-diphenyl-2H-furan-5-one,3,4-二苯基-2,5-二氢呋喃-2-酮,3,4-diphenyl-2,5-dihydrofuran-2-one |
Others | Others |
3,4-Diphenyl-5H-furan-2-one (3,4-diphenyl-2H-furan-5-one) 是一种海洋来源的天然产物,存在于Aspergillus flavipes。 | |||
T2S1702 |
(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one
1,7-双苯-5-羟基-6-庚烯-3-酮,(5R)-trans-1,7-diphenyl-5-hydroxy-6-hept,5-Hydroxy-1,7-diphenyl-6-hepten-3-one |
Antioxidant | oxidation-reduction |
(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one ((5R)-trans-1,7-diphenyl-5-hydroxy-6-hept) 是一种胡桃的二氯甲烷提取物,具有抗氧化作用。 | |||
T4S0176 |
Alnustone
(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one,桤木酮 |
Others | Others |
Alnustone ((4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one) 是一种非酚双苯庚烷类化合物,在草药和香料中发现,是姜黄的成分之一,具有抗吐、抗炎作用。 | |||
T20241 |
Diphenyl phthalate
NSC-4052,NSC 4052,NSC4052 |
||
Diphenyl phthalate is an agent of biochemical. | |||
TN2522 |
1,7-Diphenyl-4-hepten-3-one
|
Others | Others |
1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum. | |||
TMA2008 | 3-Hydroxy-1,5-diphenyl-1-pentanone | ||
(+)-3-Hydroxy-1,5-diphenyl-1-pentanone exhibits both immunomodulatory and anti-tumor activity. | |||
TN6802 | 5-Methoxy-1,7-diphenyl-3-heptanone | ||
5-Methoxy-1,7-diphenyl-3-heptanone is a natural product. | |||
TN2523 | 1,7-Diphenyl-5-hydroxy-4,6-hepten-3-one | Others | Others |
1,7-Diphenyl-5-hydroxy-4,6-hepten-3-one是一种天然产物,属于姜科山姜属,其产品编号为 TN2523,CAS号为 87095-77-0。1,7-Diphenyl-5-hydroxy-4,6-hepten-3-one可用作对照参考。 | |||
T8048 |
Diphenylamine Hydrochloride
|
Others | Others |
Diphenylamine hydrochloride 分离自 coriander ,具有抗氧化作用。在农业中,它可用作杀菌剂及抗菌剂;在工业中,它可用作抗氧化剂及染料媒染剂。 | |||
TN6339 |
(R)-5-Hydroxy-1,7-diphenylheptan-3-one
(5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮 |
Others | Others |
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) 是从中药材高良姜的根茎中提取的。它抑制茶碱刺激的鼠 B16 黑色素瘤 4A5 细胞中的黑色素生成。 | |||
TN6362 | (Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one | ||
(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6362,CAS号为 856007-75-5。 | |||
TN6357 |
5-Hydroxy-1,7-diphenylhept-6-en-3-one
|
||
5-Hydroxy-1,7-diphenylhept-6-en-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6357,CAS号为 155239-30-8。 | |||
TN2505 | 1,5-Diphenylpentan-1-one | AChR | Neuroscience |
1,5-Diphenylpentan-1-one shows poor insecticidal and acetylcholinesterase inhibitory activities. | |||
TN6486 | (3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol | ||
(3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6486,CAS号为 232261-31-3。 | |||
TN5761 | (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol | ||
(3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol has anti-oomycete potential. | |||
TN6361 |
(4Z,6E)-5-Hydroxy-1,7-diphenylhepta-4,6-dien-3-one
|
||
(4Z,6E)-5-Hydroxy-1,7-diphenylhepta-4,6-dien-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6361,CAS号为 478313-96-1。 | |||
TN1788 |
Isookanin
|
Amylase | Metabolism |
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。 | |||
T3383 |
Cimifugin
升麻素,Cimitin |
Others | Others |
Cimifugin (Cimitin) 是中草药Saposhnikovia divaricate 的一种生物活性成分。它能够调节紧密连接减少上皮衍生的主动关键因子,对过敏性炎症产生抑制作用。 | |||
T5S0281 |
Tubuloside A
|
NOS | Immunology/Inflammation |
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。 | |||
TN2211 |
Silybin B
Silibinin B |
Apoptosis; Beta Amyloid; Bcr-Abl | Angiogenesis; Apoptosis; Cytoskeletal Signaling; Neuroscience; Tyrosine Kinase/Adaptors |
Silybin B (Silibinin B) 是雷洛昔芬4′-和6-葡萄糖醛酸化的有效抑制剂,是水飞蓟素有效的抗纤维原性和抗低聚物成分,具有清除1,1-二苯基-2-吡啶酰肼(DPPH)自由基的活性 ,可通过减轻 DNA 损伤和细胞凋亡对顺铂诱导的神经毒性具有保护作用。Silybin B 对人慢性髓系白血病 K562细胞的生长抑制和诱导凋亡有较强的作用。 | |||
TN7229 |
Baihuaqianhuoside
Praeroside |
Others | Others |
Baihuaqianhuoside (Praeroside) 是一种香豆素苷。Baihuaqianhuoside 可以从西番莲和 Hindenia solanacea 的根部分离出来,是首次从 P. japonicum 身上分离出来的。Baihuaqianhuoside 在体外具有抗炎活性,可以用于炎症的研究。Baihuaqianhuoside 对1,1-二苯基-2-丙烯酰肼自由基的清除作用,以及对2,2'-偶氮双(2-脒基丙烷)二盐酸盐诱导的脂质体氧化的抑制作用。 | |||
T35749 |
Thymohydroquinone
Thymoquinol |
Antioxidant; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Thymohydroquinone (Thymoquinol) 是中药材百里香、牛至和其他唇形科植物中含有的单萜酚类化合物。 Thymohydroquinone 抑制癌细胞生长、减少氧化应激和调节炎症反应,在无细胞实验中清除2,2-二苯基-1-picrylhydrazyl 自由基(IC50 = 2.4 μg/ml),在浓度为1.6至6.4 μg/ml 的氧自由基吸收能力(ORAC)实验中,它的Trolox 当量值为2.6胸腺对苯二酚对A2780、OVCAR-8和CIS-A2780卵巢癌细胞(IC50分别为3.1、8.9和9.8 μM)和人卵巢永生化上皮细胞(IC50 = 14 μM)的生长有抑制作用,体外对恶性疟原虫也有抑制作用(IC50 = 15.9 μM)。 | |||
TN4754 | Persicoside | Others | Others |
Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. | |||
TN3193 | 6-O-Vanilloylajugol | Others | Others |
6-O-Vanilloylajugol demonstrates scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. | |||
T36513 |
Pyranonigrin A
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Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs). | |||
TN3381 |
Alnusdiol
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Others | Others |
Alnusdiol exhibits the good scavenging activities against 2, 2-diphenyl-1-picryhydrazyl (DPPH), shows moderate anti-oxidant effects. | |||
T82699 |
Cochliodinol
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Cochliodinol(化合物1)是Apis mellifera ligustica代谢产物,表现出强效的2,2-二苯基-1-苦基肼(DPPH)自由基清除能力(IC50=3.06 μg/mL)。 | |||
TN3677 |
Cleroindicin B
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Others | Others |
Cleroindicin B shows weak scavenging action on 2,2-diphenyl-l-picrylhydrazyl and hydroxyl radicals. | |||
TN3056 | 4-O-Galloylbergenin | Others | Others |
4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC50 = 28.3 uM). | |||
TN5052 |
Ssioriside
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Others | Others |
Ssioriside shows moderate antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. | |||
T75547 | Maritimetin | ||
Maritimein,一种可从雪菊提取的橙酮,具有显著的对diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) 自由基清除能力,IC50值仅为4.12 μM。该化合物因此被广泛应用于心血管疾病的研究领域。 | |||
TN4000 |
Erythristemine
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Others | Others |
(+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical. | |||
TN1503 |
Cistanoside F
肉苁蓉苷F,肉苁蓉苷 F |
NADPH-oxidase | Immunology/Inflammation |
Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.). | |||
TN1265 |
3'-O-Methylorobol
3'-O-METHYLOROBOL,3'-O-甲基香豌豆苷元 |
Others | Others |
3'-O-Methylorobol exhibits moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay, it also exerts potential analgesic properties. 3'-O-Methylorobol can increase osteoblast differentiation. | |||
TN4342 | Izalpinine | Others | Others |
Izalpinin exhibits potent antioxidant activities in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Izalpinin exhibits inhibitory role of muscarinic receptor-related detrusor contractile activity, and it may be a promising lead compound to treat overactiv | |||
TN2798 |
20-Deoxocarnosol
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ROS; Antifection | Immunology/Inflammation; Microbiology/Virology |
20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity. | |||
TN5240 |
Vitedoin A
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Others | Others |
Vitedoin A shows stronger antioxidative activity than alpha-tocopherol using the ferric thiocyanate method, it also shows higher radical-scavenging effect on the stable free radical, 1,1-diphenyl-2-picrylhydrazyl, than L-cysteine. | |||
TMA0593 | Broussoflavonol F | Tyrosinase | Proteases/Proteasome |
Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase. Broussoflavonol F | |||
T79963 |
Feralolide
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Feralolide是从芦荟树脂的甲醇提取物中分离出的一种二氢异香豆素。其作为AChE和BuChE的双抑制剂,具有IC50s分别为55 μg/mL和52 μg/mL。该化合物还表现出抗氧化活性,能够抑制2,2-diphenyl-1-picrylhydrazyl (DPPH) 和 2, 2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS)。在认知障碍如阿尔茨海默病的研究中,Feralolide可能应用于恢复和增强记忆功能。 | |||
TN4399 | Kushenol C | SGLT; NF-κB; ROS; BACE; Antifection | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB |
Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutan | |||
TN2243 |
Sugiol
10-Deoxoxanthoperol |
IL Receptor; TNF; ROS | Apoptosis; Immunology/Inflammation |
Sugiol (10-Deoxoxanthoperol) 是一种枞烷二萜,可从台湾板栗树 (Calocedrus formosana) 的树皮中分离出来。Sugiol 具有抗炎活性,可有效减少脂多糖 (LPS) 刺激巨噬细胞后的活性氧 (ROS) 产生。 | |||
T35758 | Butyrolactone V | ||
Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM).2,1 Butyrolactone V (227 and 454.1 μM) is also active against adult S. mansoni worms.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS radicals with IC50 values of 20.7 and 3.7 μM, respectively, in cell-free assays.3 Butyrolactone V also... | |||
T36179 |
Aspulvinone O
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Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu... | |||
TN4064 |
Flavoglaucin
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Phosphatase; IL Receptor; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Autophagy | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB |
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammato | |||
T36000 |
3-Hydroxyterphenyllin
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3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi... | |||
TN4584 |
Morolic acid
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IL Receptor; COX; HIV Protease | Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro |