44
3
51
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27159 |
DF-1111301
DF1111301,DF 1111301 |
Platelet aggregation; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others |
DF-1111301 是一种具有抗组胺 H1和抗PAF活性的新型抗过敏化合物。 | |||
T25317 |
DF-461
DF 461 |
||
DF-461 is an inhibitor of squalene synthase. | |||
T27158 |
DF-1012
DF 1012 |
||
DF-1012 is a 5-HT3 receptor antagonist and is also an orally-available antitussive, antiasthmatic and anti-inflammatory drug. | |||
T31408 |
DFHBI-1T
DFHBI1T,DF-HBI-1T,DF HBI 1T,DFHBI 1T |
||
DFHBI-1T 是一种可透过细胞膜的 RNA 适配体激活的荧光探针。DFHBI-1T 可以用于活细胞中的 RNA 动态定位成像。 | |||
T27158L |
DF-1012 FA
DF-1012 FA(163220-65-3 Free base) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
DF-1012 FA 是一种 DF-1012 的结构类似物,是一种神经肽类抑制剂,可用于研究哮喘和咳嗽。 | |||
T0217 |
Levodropropizine
(S)-(-)-Dropropizine,左羟丙哌嗪,DF-526 |
5-HT Receptor; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Levodropropizine ((S)-(-)-Dropropizine) 是一种组胺受体抑制剂,可用作外周镇咳药。 | |||
T4163 |
Reparixin
DF 1681Y,Repertaxin,瑞帕利辛 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Reparixin (Repertaxin) 是两种 CXCL8 受体 CXCR1/2 的强效抑制剂,它对 CXCR2 介导的细胞迁移具有微弱的抑制作用 ,IC50为 100 nM。它强烈阻断 CXCR1 介导的趋化性,IC50为 1 nM。 | |||
T0371 |
Gliquidone
AR-DF 26,格列喹酮,Glurenorm |
Potassium Channel | Membrane transporter/Ion channel |
Gliquidone (AR-DF 26) 是一种磺酰脲类的抗糖尿病药物,可用于2型糖尿病的研究。 | |||
T2409L |
Tenofovir Disoproxil Fumarate
GS-1278 Disoproxil Fumarate,Tenofovir DF,富马酸替诺福韦酯 |
HBV; HIV Protease; Reverse Transcriptase | Microbiology/Virology; Proteases/Proteasome |
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) 是一种核苷酸逆转录酶抑制剂,有潜力研究艾滋病和慢性乙型肝炎。 | |||
T27791 |
Ladarixin Sodium
DF 2156A,DF-2156,DF2156A,DF2156,DF 2156,DF-2156A |
||
Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes. | |||
T32533 |
Ladarixin
DF 2156A,DF2156A,DF-2156,DF 2156,DF-2156A,DF2156 |
||
Ladarixin is a dual, non-competitive allosteric inhibitor of CXCR1 and CXCR2 interleukin8 (IL-8a and IL-8b, respectively). The efficacy of CXCR1/2 inhibition prevents inflammation and autoimmune-mediated islet damage. | |||
T68602 |
AZ-DF 265
|
||
AZ-DF 265 is a hypoglycaemic drug which stimulates insulin release. AZ-DF-265 inhibits ATP-sensitive potassium channels and displaces [3H]-glibenclamide from the sulphonylurea receptor. | |||
TP2392 |
Neuropeptide DF2
DF(2) Neuropeptide,Drnflrfamide |
||
Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish. | |||
T82670 |
Crefmirlimab
89Zr-Df-IAB22M2C |
||
Crefmirlimab(89Zr-Df-IAB22M2C)为针对CD8抗原的人源化CD8探针,适用于多种癌症诊断。 | |||
T81849 | MAT-POS-e194df51-1 | SARS-CoV | Microbiology/Virology |
MAT-POS-e194df51-1 是一种非共价、非肽类、口服活性的SARS-CoV-2主蛋白酶 (Mpro) 抑制剂,IC50 值达 37nM。该化合物展现细胞毒性,其在 A549-ACE2-TMPRSS2 和 HeLa-ACE2 细胞线上的 EC50 值分别为 64 nM 和 126 nM。 | |||
T15106 |
DFHBI
|
Others | Others |
DFHBI 是类似于绿色荧光蛋白发色团的小分子。 Spinach-DFHBI 复合物在体外和活细胞中都具有明亮的荧光,而pinach 和 DFHBI 在未结合时基本不发荧光。 | |||
TP2483L |
Cyclo(-RGDfC)acetate
Cyclo(-RGDfC)acetate(862772-11-0 free base) |
Others | Others |
Cyclo(-RGDfC)acetate 是一种整合素 avb3 亲和多肽,一种环状 RGDfc 序列。 | |||
TP1330 |
Cyclo(RADfK)
|
Integrin | Cytoskeletal Signaling |
Cyclo(RADfK) 是选择性 α(v)β(3) 整合素配体,广泛用于新血管生成的研究、治疗和诊断。它是 cyclo (-RGDfK-) 的阴性对照, RGD 肽。 RGD 肽是细胞粘附的调节剂,并被整合素家族的几个成员识别。 | |||
T11014 |
DFP00173
|
Aquaporin | Membrane transporter/Ion channel |
DFP00173 是一种aquaporin-3 (AQP3)的选择性抑制剂。它对 AQP3 的选择性高于同源 AQP 亚型 AQP7 和 AQP9。它能够抑制小鼠和人 AQP3,IC50值为 ~0.1-0.4 μM。 | |||
T5537 |
IDF-11774
|
HIF/HIF Prolyl-Hydroxylase; HIF | Angiogenesis; Chromatin/Epigenetic; Metabolism |
IDF-11774 是新型低氧诱导因子 α (HIFα)-1的抑制剂,其 IC50=3.65 μM。。 | |||
T31409 |
DFHO
|
||
DFHO 是一种激发后可散发黄色荧光的 Corn 同源配体,用于活细胞中 RNA 的成像。 | |||
T6812 |
Cyclo(-RGDfK)
Cyclo (-RGDfK) |
Integrin | Cytoskeletal Signaling |
Cyclo(-RGDfK) (Cyclo (-RGDfK)) 是一种选择性整合素αvβ3的有效抑制剂,IC50值为 0.94 nM。它通过与细胞表面的 αvβ3 整合素结合,特异性靶向肿瘤微血管和癌细胞。 | |||
T6812L |
Cyclo(-RGDfK) TFA
|
Integrin | Cytoskeletal Signaling |
Cyclo(-RGDfK) TFA 是一种选择性整合素αvβ3的有效抑制剂,其IC50值为 0.94 nM。它通过与细胞表面的 αvβ3 整合素结合,特异性靶向肿瘤微血管和癌细胞。 | |||
T80214 |
cRGDfK-thioacetyl ester
|
Integrin | Cytoskeletal Signaling |
cRGDfK-thioacetyl ester 为具选择性亲和力于整合素(integrins)之生物活性多肽。可应用于修饰NIR荧光探针,实现癌症靶向成像。 | |||
T26757 |
BDF 9148
BDF-9148,BDF9148 |
||
BDF 9148, a Na(+)-channel modulator, increases the contractile force of guinea-pig atria and papillary muscles. | |||
T41173 |
FAM-DEALAHypYIPMDDDFQLRSF
|
||
FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluorescence polarization (FP) displacement assay. Excitation/emission maxima (λ) = 485/520 nm. This product is a longer peptide version of FAM-DEALA-Hyp-YIPD. | |||
T37629 |
IDFP
|
||
The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) hydrolyze 2-AG and AEA, respectively, thus terminating their biological function. IDFP is an organophosphorus compound that dually inhibits MAGL and F... | |||
T62106 |
(Rac)-ErSO-DFP
|
||
(Rac)-ErSO-DFP 是一种 ErSO-DFP 的衍生物,也是一种选择性小分子 Erα 生物调节剂。(Rac)-ErSO-DFP 能够过度激活 ERα+ 依赖性的预期未折叠蛋白反应,表现出抗雌激素受体 α 阳性乳腺癌 (包括其抗性肿瘤) 的作用。 | |||
T82642 |
Cyclo(RGDfK(Mal))
|
||
Cyclo(RGDfK(Mal))为一种五肽,能促进人多能干细胞的附着与渗透,适用于三维干细胞培养及其扩增。 | |||
T80130 |
SDF-1α (human)
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
SDF-1α (human) 是一种能够与CXCR4受体相结合的单核细胞趋化剂,它在心肌梗死模型中的干细胞归巢、维持、生存、增殖、心肌细胞修复、血管形成以及心室重构过程扮演关键角色。SDF-1α (human) 常用于心血管病研究。 | |||
T18597 |
dFKBP-1
|
Others | Others |
dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1]. | |||
T82761 |
CDFI
|
||
CDFI为MurJ(脂质II翻转酶)的抑制剂,能够提升β-内酰胺类对抗MRSA的活性。 | |||
T70632 | DFL23448 | ||
DFL23448 is a TRPM8-selective ion channel antagonist, modifying bladder function and reduces bladder overactivity in awake rats. | |||
T15107 |
DFMTI
MK5435 |
Others | Others |
DFMTI can completely block the rmGlu1 L757V glutamate response. | |||
T39022 |
DFHBI-2T
|
||
DFHBI-2T, a membrane-permeable fluorescence probe activated by RNA aptamers (ex/em=500 nm/523 nm), is utilized for imaging RNA within live cells. | |||
T82516 |
E(c(RGDfK))₂
|
||
E(c(RGDfK))是一种针对αvβ3整联蛋白的特异性结合片段,表现出对肿瘤的靶向作用。在人卵巢癌OVCAR-3异种移植肿瘤模型中,该化合物的摄取有所提升,适用于癌症研究领域。 | |||
TP1847 |
GLGPNPCRKKCYKRDFLGR
|
||
GLGPNPCRKKCYKRDFLGR is a synthetic peptide. | |||
T61081 |
DFPM
|
||
DFPM, a chemical compound, acts as an activator of the plant resistance protein signaling in roots, thereby causing inhibition of root growth. It also reduces the viability of root cells specifically in the Col-0 accession. Notably, DFPM displays sensitivity to light when dissolved in aqueous solutions. It acquires bioactivity through light-induced and oxygen-dependent modification [1]. | |||
T62108 | ErSO-DFP | ||
ErSO-DFP 是一种预期的未折叠蛋白反应 (a-UPR) 激活剂。ErSO-DFP 能够提高对雌激素受体α+ (ERα+) 癌细胞的选择性,选择性高于 ErSO。ErSO-DFP 具有抗肿瘤作用,能够明显消除小鼠模型中 MCF-7 肿瘤。 | |||
T61818 | DFBTA | ||
DFBTA is a highly effective and orally active inhibitor of ANO1, specifically the calcium-activated chloride channel anoctamin-1. It exhibits potent inhibitory activity, with an IC 50 of 24 nM. Notably, DFBTA demonstrates significant analgesic efficacy in treating inflammatory pain [1]. | |||
T78433 |
DfTat
|
||
DfTat为TAT细胞穿透肽的荧光标记二聚体,具有极高效率向活细胞输送小分子、多肽和蛋白质的能力。标记有罗丹明的DfTat可用作便于检测的示踪剂。 | |||
T80336 |
DFTamP1
|
||
DFTamP1为抗菌肽,针对金黄色葡萄球菌USA300表现出活性,其最小抑菌浓度(MIC)为3.1 μM。 | |||
T82574 |
DFAME
|
||
DFAME为一种帶有红色荧光的基团(Ex=508 nm,Em=641 nm)。它能与二聚体荧光RNA适体Beetroot及Corn结合,分别形成Beetroot-DFAME复合体(Kd=460 nM)和Corn-DFAME复合体(Kd=3600 nM)。这两种复合体可应用于细胞内RNA组装体的形成,利用RNA结构的自组装特性研究RNA纳米结构。 | |||
T75408 | Batroxobin | ||
Batroxobin (DF-521),一种从Bothrops atrox moojeni获得的蛇毒,能促进血栓溶解,防止血栓复发并具有神经保护作用,显示出在脑静脉血栓性疾病研究中的潜力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75627 | Ganoderic acid Df | ||
Ganoderic acid Df 是一种羊毛甾烷型三萜类化合物,可从灵芝的子实体中分离得到。Ganoderic acid Df 有效抑制醛糖还原酶 (aldose reductase),其 IC50为 22.8 ± 0.6 μM。 | |||
T81920 |
LNnDFH I
Lacto-N-neo-difucohexaose I |
||
LNnDFH I是从人体尿液中分离出的天然产物。 | |||
TN3066 |
4-Oxobedfordiaic acid
|
Others | Others |
4-Oxobedfordiaic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3066,CAS号为 68799-38-2。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02167 |
Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)
DF,Adn,complement factor D (adipsin) |
Mouse | HEK293 Cells |
Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P03953-2. | |||
TMPY-02183 |
Complement Factor D/CFD Protein, Human, Recombinant (His)
PFD,DF,complement factor D (adipsin),ADN,FACTOR D,A... |
Human | HEK293 Cells |
Complement Factor D/CFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P00746. | |||
TMPH-03272 |
Complement factor D Protein, Rat, Recombinant (His)
Adipsin,Df,Adn,C3 convertase activator,Complement f... |
Rat | P. pastoris (Yeast) |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. | |||
TMPK-00671 |
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Adipsin,CFD,ADN,Complement factor D,DF,AMBP-1,EC 3.... |
Rhesus | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Rhesus macaq... | |||
TMPK-00151 |
Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
C3 convertase activator,AMBP-1,PFD,FACTOR D,CFD,ADN,EC 3.4.2... |
Mouse | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recom... | |||
TMPJ-00149 |
Complement Factor D/CFD Protein, Mouse, Recombinant (His)
C3 convertase activator,28 kDa adipocyte protein,Cfd,Adipsin... |
Mouse | HEK293 Cells |
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the... | |||
TMPH-03271 |
Complement factor D Protein, Rat, Recombinant (His & Myc)
Adn,C3 convertase activator,Properdin factor D,Complement fa... |
Rat | HEK293 Cells |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is P32038. | |||
TMPK-00755 |
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
C3 convertase activator,DF,AMBP-1,EC 3.4.21,EC 3.4.... |
Human | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recom... | |||
TMPY-01073 |
GDF-15 Protein, Human, Recombinant (hFc)
PTGFB,PLAB,MIC-1,MIC1,PDF,NAG-1,growth differentiat... |
Human | HEK293 Cells |
GDF-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number is Q99988. | |||
TMPK-01243 |
GDF-15 Protein, Rat, Recombinant (His)
GDF-15,PDF,PTGF-beta,MIC-1,MIC1,GDF |
Rat | E. coli |
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6. | |||
TMPY-02591 |
SDF-1 Protein, Human, Recombinant
SDF1,chemokine (C-X-C motif) ligand 12,TPAR1,SD... |
Human | E. coli |
SDF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.6 kDa and the accession number is P48061-1. | |||
TMPY-00740 |
SDF-1 Protein, Human, Recombinant (hFc)
PBSF,IRH,chemokine (C-X-C motif) ligand 12,SDF1,SCY... |
Human | HEK293 Cells |
SDF-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is P48061-1. | |||
TMPK-01246 |
GDF-15 Protein, Mouse, Recombinant (His)
MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-... |
Mouse | E. coli |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... | |||
TMPY-04727 |
GDF-15 Protein, Human, Recombinant (His)
PLAB,PTGFB,NAG-1,MIC1,GDF-15,PDF,MIC-1,gro... |
Human | P. pastoris (Yeast) |
GDF-15 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 13.7 kDa and the accession number is Q99988. | |||
TMPY-02820 |
SDF-1 Protein, Human, Recombinant (isoform a)
SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB12,T... |
Human | E. coli |
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2. | |||
TMPJ-00693 |
EDF1 Protein, Human, Recombinant (His)
Multiprotein-Bridging Factor 1,EDF-1,Endothelial Di... |
Human | E. coli |
Endothelial Differentiation-Related Factor 1 (EDF1) is a 148 amino acid transcriptional coactivator that contains 1 HTH cro/C1-type DNA-binding domain. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. When endothelial cells are induced to differentiate in vitro, EDF1 is downregulated, leading to inhibition o... | |||
TMPH-01413 |
GDF11 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. GDF11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression... | |||
TMPY-02184 |
SDF-1 Protein, Rhesus, Recombinant (hFc)
chemokine (C-X-C motif) ligand 12 |
Rhesus | HEK293 Cells |
SDF-1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is Q0MSE6. | |||
TMPY-04534 |
GDF-8 Protein, Mouse, Recombinant (hFc)
骨肉瘤源生长因子,Cmpt,myostatin,Gdf8 |
Mouse | HEK293 Cells |
GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF-8 / Myostatin / MSTN is highly expressed in skeletal muscle, and myostatin loss-of-function le... | |||
TMPK-01244 |
GDF-15 Protein, Mouse, Recombinant (hFc)
PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF... |
Mouse | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... | |||
TMPH-01236 |
DFFB Protein, Human, Recombinant (His)
DNA fragmentation factor 40 kDa subunit,Caspase-activated DN... |
Human | E. coli |
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. | |||
TMPJ-00483 |
DFF45 Protein, Human, Recombinant (His)
DNA Fragmentation Factor Subunit Alpha,DFF45,H13,IC... |
Human | E. coli |
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. | |||
TMPY-02749 |
SDF-1 Protein, Human, Recombinant (His)
SDF1,IRH,chemokine (C-X-C motif) ligand 12,PBSF,TLS... |
Human | E. coli |
SDF-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10kDa and the accession number is P48061-2. | |||
TMPH-01016 |
GDF-10 Protein, Human, Recombinant (His)
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Human | E. coli |
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. GDF-10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is P55107. | |||
TMPY-01817 |
GDF-10 Protein, Mouse, Recombinant (hFc)
growth differentiation factor 10,Bmp3b |
Mouse | HEK293 Cells |
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. In th... | |||
TMPH-01416 |
GDF9 Protein, Human, Recombinant (GST)
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Human | E. coli |
GDF9 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.5 kDa and the accession number is O60383. | |||
TMPJ-00713 |
GDF-11 Protein, Human, Recombinant
Growth/differentiation factor 11,Bone morphogenetic protein ... |
Human | HEK293 Cells |
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The si... | |||
TMPH-03482 |
Sandfly fever sicilian virus (SFS) Nucleoprotein/NP Protein (His)
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SFSV | E. coli |
Sandfly fever sicilian virus (SFS) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.0 kDa and the accession number is P12793. | |||
TMPY-01328 |
PEDF Protein, Human, Recombinant (His)
serpin peptidase inhibitor, clade F,member 1,OI6,OI12,EPC-1,... |
Human | HEK293 Cells |
PEDF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.8 kDa and the accession number is A0A140VKF3. | |||
TMPJ-00663 |
GDF-8 Protein, Human/Mouse/Rat, Recombinant
骨肉瘤源生长因子,Gdf8,Mstn,GDF-8,Growth/differenti... |
Human,Mouse,Rat | HEK293 Cells |
Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically a... | |||
TMPK-00198 |
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF... |
Human | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPK-00664 |
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15,NAG... |
Cynomolgus | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPY-00266 |
PEDF Protein, Rat, Recombinant (His)
serpin peptidase inhibitor, clade F,member 1 |
Rat | HEK293 Cells |
PEDF Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.9 kDa and the accession number is Q68G45. | |||
TMPY-02274 |
SDF-2 Protein, Mouse, Recombinant (His)
stromal cell-derived factor 2,AI853825 |
Mouse | Baculovirus Insect Cells |
SDF-2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is Q9DCT5. | |||
TMPJ-01414 |
GDF-15 Protein, Mouse, Recombinant (His & Flag)
Growth Differentiation Factor 15, Macrophage inhibitory cyto... |
Mouse | HEK293 Cells |
Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito... | |||
TMPY-01112 |
PEDF Protein, Mouse, Recombinant (His)
AI195227,Pedfl,Sdf3,Pedf,EPC-1,se... |
Mouse | HEK293 Cells |
PEDF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.8 kDa and the accession number is P97298. | |||
TMPH-01414 |
GDF2 Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. GDF2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is Q9UK05. | |||
TMPK-00197 |
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTGF-beta,P<... |
Human | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPH-02137 |
FDFT1 Protein, Human, Recombinant (His)
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Human | E. coli |
FDFT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 52.0 kDa and the accession number is P37268. | |||
TMPH-02914 |
SDF2L1 Protein, Mouse, Recombinant (His & Myc)
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Mouse | P. pastoris (Yeast) |
SDF2L1 Protein, Mouse, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 24.4 kDa and the accession number is Q9ESP1. | |||
TMPK-00665 |
GDF-15 Protein, Cynomolgus, Recombinant (His)
PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β... |
Cynomolgus | E. coli |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... | |||
TMPK-01245 |
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
RG-1,GDF15,Placental TGF-beta,GDF-15,PTGFB... |
Mouse | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPK-00663 |
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTG... |
Cynomolgus | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... | |||
TMPY-03580 |
SDF-1 Protein, Canine, Recombinant
chemokine (C-X-C motif) ligand 12 |
Canine | E. coli |
SDF-1 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.6 kDa and the accession number is A0A8C0NWR9. | |||
TMPK-00196 |
GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated
NAG-1,Placental TGF-beta,PTGFBPTGF-β,PDF,Placental ... |
Human | E. coli |
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession nu... | |||
TMPH-00353 |
GDF-8 Protein, Feline, Recombinant
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Feline | E. coli |
GDF-8 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 40.7 kDa and the accession number is M3WPT7. | |||
TMPJ-00966 |
GDF-5 Protein, Human, Recombinant
Lipopolysaccharide-associated protein 4,Cartilage-derived mo... |
Human | E. coli |
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor protein consisting of a 354 amino acid (aa) Nterminal proregion and a 120 aa C-terminal mature peptide. Mature human GDF-5 shares 99% aa sequence identity with both mature mouse and rat GDF-5. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a ty... | |||
TMPK-00569 |
GDF-15 Protein, Canine, Recombinant (His)
GDF15,MIC1,MIC-1,PLAB,GDF-15,PDF,... |
Canine | E. coli |
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6. | |||
TMPH-02317 |
YTHDF1 Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability by promoting degradation of m6A-containing mRNAs via interaction with the CCR4-NOT complex. The YTHDF paralogs (YTHDF1, YTHDF2 and YTHDF3) shares m6A-containing mRNAs targets and act redundantly to mediate mRNA degradatio... | |||
TMPY-03289 |
SDF-1 Protein, Mouse, Recombinant
Scyb12,Tpar1,Pbsf,chemokine (C-X-C motif) ligand 12,Sdf<... |
Mouse | E. coli |
SDF-1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.1 kDa and the accession number is P40224-1. | |||
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