首页工具

登录

搜索结果

Search Results for " hyperplasia "

50

抑制剂 & 化合物

5

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T0488	Finasteride 非那雄胺,MK-906	Reductase	Endocrinology/Hormones; Metabolism
	Finasteride (MK-906) 是 5α-还原酶的竞争性抑制剂，对 II 型 5α-还原酶的IC50为 4.2 nM，对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。
T0696	Naftopidil KT-611,萘哌地尔,BM-15275	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil (KT-611) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM 、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T1504	Silodosin 西洛多辛,KAD 3213,KMD 3213	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Silodosin (KAD 3213) 是有选择性的、强效的、口服活性的 α1A-adrenergic receptor 阻滞剂，是一种有效且耐受性良好的试剂，可用于研究 LUTS/BPH。它对 α1A-AR 表现出高度的亲和力，是 α1B-AR 和 α1D-AR 亲和力的 162 和 50 倍。
T0197	Terazosin hydrochloride 盐酸特拉唑嗪,Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Terazosin hydrochloride (Hytrin) 是一种竞争性和口服活性的 α1-肾上腺素受体拮抗剂，是一种喹唑啉衍生物。它通过舒张血管和打开膀胱来起作用。它可用于良性前列腺增生和高血压的研究。
T6600	Naftopidil dihydrochloride KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil dihydrochloride (KT-611 2HCl) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T6701	Terazosin hydrochloride dihydrate Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate,盐酸特拉唑嗪(二水合物)	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Terazosin hydrochloride dihydrate (Heitrin dihydrate) 是一种竞争性和口服活性的 α1-肾上腺素受体(α1-adrenoceptor) 拮抗剂，是一种喹唑啉衍生物，通过舒张血管和打开膀胱的方式起作用。它可用于研究良性前列腺增生 (BPH) 和高血压。
T6461	Dapoxetine hydrochloride LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,盐酸达泊西汀,Priligy	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Dapoxetine hydrochloride (LY-210448 hydrochloride) 是一种具有口服活性的、选择性的血清素再摄取 (serotonin reuptake) 抑制剂 (SSRI)，可用于研究早泄 (PE) 。
T9220	Naftopidil hydrochloride 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil hydrochloride (BM-15275 hydrochloride) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力 Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T0039	Dapoxetine 达波西汀,Dapoxetina,Dapoxetinum	Others; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	Dapoxetine (Dapoxetina) 是一种选择性5-羟色胺再摄取抑制剂，用于治疗早泄。
T13703	Gestonorone Capronate	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Gestonorone Capronate 是一种孕激素，在良性前列腺肥大和子宫内膜癌领域有研究价值。
T14843	Bifluranol BX341	Androgen Receptor	Endocrinology/Hormones
	Bifluranol (BX341) 具有抗雄激素活性，在体内实验中显示出显著的抗前列腺活性，可用于治疗良性前列腺增生（BPH）。
T31095	Crinecerfont SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A	CRFR	GPCR/G Protein
	Crinecerfont (SSR-125543) 是促肾上腺皮质激素释放因子 1 受体 (CRF1) 的特异性拮抗剂，可用于经典先天性肾上腺增生的研究。
T22316	Doxazosin UK 33274,多沙唑嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Doxazosin (UK 33274) 是选择性的拮抗突触后的α1肾上腺素受体。
T76978	Siltuximab CNTO-328	IL Receptor	Immunology/Inflammation
	Siltuximab（CNTO-328）是一种靶向 IL-6 且具有抗肿瘤活性的单克隆抗体，可用于研究巨大淋巴结增生症 (MCD) 和 COVID-19。
T27798	Lapisteride CS891B,CS-891,CS-891B,CS891	Others	Others
	Lapisteride (CS-891) 一种类固醇5α-还原酶抑制剂，可用于治疗良性前列腺增生(BPH)和雄激素性脱发，可有效预防或治疗AGA 。
T28922	Taprizosin Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Taprizosin（UK-338003）是一种具有选择性和口服活性的 α1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，可用于舒张血管，用于治疗良性前列腺增生症。
T15688	L-771688 SNAP 6383	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-771688（SNAP 6383）是一种新型有效和选择性的 α1A-肾上腺素受体拮抗剂， Ki 值为 0.43±0.02 nM。L-771688 KE 用于治疗良性前列腺增生。
T26278	Tildacerfont	CRFR	GPCR/G Protein
	Tildacerfont 是 CRF1 的拮抗剂，可降低促肾上腺皮质激素和肾上腺雄激素的水平。 Tildacerfont 可用于先天性肾上腺增生的研究。
T0091	Alfuzosin hydrochloride SL 77499-10,Alfuzosin HCl,盐酸阿夫唑嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Alfuzosin hydrochloride (Alfuzosin HCl) 是一种 α1 肾上腺素受体拮抗剂，可用于良性前列腺增生(BPH)的研究。
T1499	Dutasteride GG 745,Avodart,度他雄胺,GI 198745	Apoptosis; Reductase	Apoptosis; Endocrinology/Hormones; Metabolism
	Dutasteride (GI 198745) 是一种 5α 还原酶同工酶抑制剂，还可能因其结构域 DHT 相似对雄激素受体产生脱靶效应。
T35182	Xinidamine BRN 0891979,Xinidaminum,Xinidamino
	Xinidamine (BRN 0891979) 具有抗肿瘤活性，可用于研究良性前列腺增生、黄斑变性和前列腺上皮内瘤。Xinidamine 对PWR-1E 细胞的增殖具有抑制作用，IC50为4μM。
T11286	Fiduxosin A 185980.1,ABT 980	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fiduxosin 是一种具有选择性和有效性的 α1-adrenoceptor 拮抗剂，对 α1a-adrenoceptor，α1b-adrenoceptor 和 α1d-adrenoceptor 有抑制作用，Ki 值分别为 0.160 nM，24.9 nM 和 0.920 nM。Fiduxosin 可用于治疗良性前列腺增生。
T0210L	Tamsulosin LY253351 free base,HSDB7744,(R)-(-)-YM12617 free base,Harnal-D,Flowmax,HSDB 7744,HSDB-7744	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Tamsulosin ((R)-(-)-YM12617 free base) 是一种肾上腺素能受体α 1A 拮抗剂，用于良性前列腺增生(BPH)的治疗。Tansulosin 用于治疗排尿困难，这是前列腺肥大的一种常见症状。Tansulosin 和其他被称为α受体阻滞剂的药物通过放松膀胱颈部肌肉和前列腺本身的肌肉纤维来发挥作用，使其更容易排尿。
T68123	Oxodipine	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Oxodipine 是一种二氢吡啶型钙拮抗剂，抑制了KCl 诱导的兔主动脉收缩，降低了效力较低的大鼠心室试纸收缩的心脏力量。在大鼠培养的新生儿心室肌细胞中，Oxodipine 降低了L 型Ca 电流（I），IC 为0.24μM，对T 型Ca 电流（I）的IC 为0.41μM。Oxodipine 会使小鼠便秘和狗牙龈增生。
T22232	Alfuzosin
	Alfuzosin 是选择性和竞争性的α1肾上腺素受体拮抗剂，可用于良性前列腺增生（BPH）的研究。
T70396	Fexapotide triflutate
	Fexapotide triflutate is a caspase and TNF signaling pathway activator used to treat benign prostatic hyperplasia (BPH).
T28956	TF-505 FR-146687,FK-687,TF 505,FK687
	TF-505, a steroid 5α-reductase inhibitor, is used potentially for the treatment of benign prostatic hyperplasia.
T20024	Tadalafil, (6R ,12aS)- Tadalafil (6R ,12aS)- Lilly,Tadalafil specified impurity A,(-)-Tadalafil (6R ,12aS) diastereomer
	Tadalafil is a carboline derivative and Phosphodiesterase 5 Inhibitor. It is used primarily to treat Erectile dysfunction, Benign Prostatic Hyperplasia, and Primary Pulmonary Hypertension.
T33826	Osaterone
	Osaterone is effective against prostatic hyperplasia in dogs.
T32029	GYKI-16084 GYKI 16084
	GYKI-16084 is a postsynaptic alpha2 receptor blocker with potential efficacy in the treatment of benign prostatic hyperplasia.
T71793	CDMG1
	CDMG1 is a novel Wnt inhibitor, promoting heart regeneration, injury repair, and myocardial hyperplasia through expansion of the cardiac progenitor cell population
T24378	L-771688 dihydrochloride L 771688 dihydrochloride
	L-771688 is an α1A-adrenoceptor antagonist potentially for the treatment of benign prostatic hyperplasia.
T38697	[Tyr(P)4] Angiotensin II
	[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.
T40398	Crinecerfont hydrochloride SSR-125543A,SSR-125543 hydrochloride
	Crinecerfont hydrochloride (SSR-125543) is a highly potent, orally active, non-peptide antagonist of the CRF1 receptor. It has demonstrated efficacy in the context of Classic congenital adrenal hyperplasia (CAH) research.
T3290L	Pikamilone Sodium GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na
	Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.
T69927	Fiduxosin hydrochloride
	Fiduxosin hydrochloride is an alpha 1a-adrenoceptor antagonist that may be useful in the treatment of Benign Prostatic Hyperplasia.
TP1224	[Sar1, Ile8]-Angiotensin II TFA Angiotensin 2 TFA,AngiotensinII TFA
	[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that exerts various effects on vascular smooth muscle. These effects include the contraction of normal arteries as well as the hypertrophy or hyperplasia of cultured cells or diseased vessels.
T61729	Terazosin
	Terazosin, a quinazoline derivative, is an orally active and competitive antagonist of α1-adrenoceptors. Its mechanism of action involves relaxing blood vessels and promoting bladder opening. Terazosin exhibits therapeutic potential for treating benign prostatic hyperplasia (BPH) and high blood pressure [1][2][3].
T79793	CRF1 receptor antagonist-1	CFTR	Membrane transporter/Ion channel
	CRF1 receptor antagonist-1 (Compound 2)为CRF1受体拮抗剂，适用于先天性肾上腺增生症(CAH)的研究领域。
T28245	ONO-0300302 ONO 0300302
	ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over
T35665	Pregnanetriol
	Pregnanetriol is a metabolite of 17α-hydroxyprogesterone .1,2It is formed from 17α-hydroxyprogesterone by reduction of the C-20 ketone.2Urinary levels of pregnanetriol are elevated in patients with 21-hydroxylase deficiency and congenital adrenal hyperplasia.3,4 1.Kamrath, C., Hartmann, M.F., Boettcher, C., et al.Diagnosis of 21-hydroxylase deficiency by urinary metabolite ratios using gas chromatography-mass spectrometry analysis: Reference values for neonates and infantsJ. Steroid Biochem. Mol...
T83428	1-Myristoyl-3-chloropropanediol
	1-Myristoyl-3-chloropropanediol 是一种MCPD (3-一氯丙二醇) 脂肪酸酯。慢性口服该化合物可导致肾病、小管增生和腺瘤形成，在大鼠中也观察到生育能力下降，不育发生率增加，以及免疫功能受到抑制。
T35519	Aflatoxin B2-13C17 Aflatoxin B2-13C17
	Aflatoxin B2-13C17(AFB2-13C17) is intended for use as an internal standard for the quantification of AFB2by GC- or LC-MS. AFB2is a mycotoxin that has been found inA. terricola.1It induces hepatic autophagy and apoptosis in broiler chickens when administered at doses of 0.2, 0.4, and 0.8 mg/kg.2AFB2(0.5 and 1 mg/animal) also induces parenchymal cell hyperplasia in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Alimen...
T76275	Fexapotide
	Fexapotide (NX-1207 free acid) 在细胞水平上通过选择性诱导细胞凋亡，降低前列腺体积。它主要用于研究下尿路症状(LUTS)与良性前列腺增生(BPH)。
T21814	ONO 4817
	ONO-4817 是一种广谱基质金属蛋白酶 (MMP) 抑制剂。抑制基质金属蛋白酶 (MMP) 有望抑制动脉粥样硬化新内膜增殖，从而限制动脉粥样硬化斑块的进展。ONO-4817 抑制实验性高脂血症兔主动脉内膜增生的发展。
T37983	GM 1489
	GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2'-deoxycytidine-induced increases in MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, and MMP-14 expression as well as cell invasion in AsPC-1, BxPC-3, Hs766T, MiaPaCa2, and PANC-1 cancer cells. Topical administration of GM 1489 (100 μg) inhibits increases in ear thickness and epidermal hyperplasia induced by phor...
T76242	MMI-0100
	MMI-0100 是一种细胞渗透性肽抑制剂，抑制丝裂原活化蛋白激酶活化蛋白激酶 II (MK2)。MMI-0100 在体内外减少内膜增生。MMI-0100 抑制IL-6表达而不影响IL-8表达。MMI-0100 抑制纤维化过程，例如静脉移植疾病。
T21668	Finasteride acetate
	Finasteride (MK-906) acetate 是一种高效的5α-还原酶 (5α-reductase) 竞争性抑制剂，其对 II 型 5α-还原酶的IC50值仅为 4.2 nM，其对该型酶的亲和力是对 I 型酶亲和力的约100倍。因此，Finasteride acetate 主要在良性前列腺增生症 (BPH) 和雄激素性脱发研究领域中应用。
T36380	GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
	GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans...
T35579	PKSI-527
	PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and λ-carrageenan ex vivo in human plasma. It also prolongs partial thromboplastin and euglobulin clot lysis times. In vivo, PKSI-527 (300 mg/kg per day) reduces hyperplasia, pannus formation, and infiltration of in...

化合物

Cat.No: T0488

Synonym: 非那雄胺,MK-906

Target: Reductase

Cat.No: T0696

Synonym: KT-611,萘哌地尔,BM-15275

Target: Adrenergic Receptor

Cat.No: T1504

Synonym: 西洛多辛,KAD 3213,KMD 3213

Target: Adrenergic Receptor

Terazosin hydrochloride

Cat.No: T0197

Synonym: 盐酸特拉唑嗪,Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic

Target: Adrenergic Receptor

Naftopidil dihydrochloride

Cat.No: T6600

Synonym: KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl

Target: 5-HT Receptor, Adrenergic Receptor

Terazosin hydrochloride dihydrate

Cat.No: T6701

Synonym: Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate,盐酸特拉唑嗪(二水合物)

Target: Adrenergic Receptor

Dapoxetine hydrochloride

Cat.No: T6461

Synonym: LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,盐酸达泊西汀,Priligy

Target: 5-HT Receptor, Serotonin Transporter

Naftopidil hydrochloride

Cat.No: T9220

Synonym: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride

Target: Adrenergic Receptor

Cat.No: T0039

Synonym: 达波西汀,Dapoxetina,Dapoxetinum

Target: Others, 5-HT Receptor

Gestonorone Capronate

Cat.No: T13703

Target: Prostaglandin Receptor

Cat.No: T14843

Synonym: BX341

Target: Androgen Receptor

Cat.No: T31095

Synonym: SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A

Target: CRFR

Cat.No: T22316

Synonym: UK 33274,多沙唑嗪

Target: Adrenergic Receptor

Cat.No: T76978

Synonym: CNTO-328

Target: IL Receptor

Cat.No: T27798

Synonym: CS891B,CS-891,CS-891B,CS891

Target: Others

Cat.No: T28922

Synonym: Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003

Target: Adrenergic Receptor

Cat.No: T15688

Synonym: SNAP 6383

Target: Adrenergic Receptor

Cat.No: T26278

Target: CRFR

Alfuzosin hydrochloride

Cat.No: T0091

Synonym: SL 77499-10,Alfuzosin HCl,盐酸阿夫唑嗪

Target: Adrenergic Receptor

Cat.No: T1499

Synonym: GG 745,Avodart,度他雄胺,GI 198745

Target: Apoptosis, Reductase

Cat.No: T35182

Synonym: BRN 0891979,Xinidaminum,Xinidamino

Cat.No: T11286

Synonym: A 185980.1,ABT 980

Target: Adrenergic Receptor

Cat.No: T0210L

Synonym: LY253351 free base,HSDB7744,(R)-(-)-YM12617 free base,Harnal-D,Flowmax,HSDB 7744,HSDB-7744

Target: Adrenergic Receptor

Cat.No: T68123

Target: Calcium Channel

Cat.No: T22232

Fexapotide triflutate

Cat.No: T70396

Cat.No: T28956

Synonym: FR-146687,FK-687,TF 505,FK687

Tadalafil, (6R ,12aS)-

Cat.No: T20024

Synonym: Tadalafil (6R ,12aS)- Lilly,Tadalafil specified impurity A,(-)-Tadalafil (6R ,12aS) diastereomer

Cat.No: T33826

Cat.No: T32029

Synonym: GYKI 16084

Cat.No: T71793

L-771688 dihydrochloride

Cat.No: T24378

Synonym: L 771688 dihydrochloride

[Tyr(P)4] Angiotensin II

Cat.No: T38697

Crinecerfont hydrochloride

Cat.No: T40398

Synonym: SSR-125543A,SSR-125543 hydrochloride

Pikamilone Sodium

Cat.No: T3290L

Synonym: GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na

Fiduxosin hydrochloride

Cat.No: T69927

[Sar1, Ile8]-Angiotensin II TFA

Cat.No: TP1224

Synonym: Angiotensin 2 TFA,AngiotensinII TFA

Cat.No: T61729

CRF1 receptor antagonist-1

Cat.No: T79793

Target: CFTR

Cat.No: T28245

Synonym: ONO 0300302

Cat.No: T35665

1-Myristoyl-3-chloropropanediol

Cat.No: T83428

Aflatoxin B2-13C17

Cat.No: T35519

Synonym: Aflatoxin B2-13C17

Cat.No: T76275

Cat.No: T21814

Cat.No: T37983

Cat.No: T76242

Finasteride acetate

Cat.No: T21668

GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)

Cat.No: T36380

Cat.No: T35579

Cat. No.	Product Name	Target	Signaling Pathways
TN5031	Sitostenone 豆甾-4-烯-3-酮	Others	Others
	Sitostenone 具有抗氧化活性。 Stigmasta-4-en-3-one(Sitostenone)可用于治疗雄激素依赖性疾病，尤其是治疗良性前列腺增生。
T36915	21-Deoxycortisol
	21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. 1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive...
TN1061	Ganoderol B	Androgen Receptor	Endocrinology/Hormones
	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy through suppressing the function of andr
TN4582	Moracin T	c-Myc; COX	Cell Cycle/Checkpoint; Immunology/Inflammation; Neuroscience
	Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermo
TN4819	(-)-Praeruptorin A	ATPase; IL Receptor; Calcium Channel; P-gp	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs.

天然产物

Cat.No: TN5031

Synonym: 豆甾-4-烯-3-酮

Target: Others

21-Deoxycortisol

Cat.No: T36915

Cat.No: TN1061

Target: Androgen Receptor

Cat.No: TN4582

Target: c-Myc, COX

(-)-Praeruptorin A

Cat.No: TN4819

Target: ATPase, IL Receptor, Calcium Channel, P-gp

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼