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Search Results for " uva "

75

抑制剂 & 化合物

24

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9048	Ecamsule	Others	Others
	Ecamsule 是一种亚苄基樟脑衍生物，其中许多以其出色的光稳定性而闻名。可添加到防晒霜中以过滤掉 UVA 射线。
T19310	Ensulizole 2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID,苯基苯丙咪唑磺酸,2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid,Phenylbenzimidazole sulfonic acid	Others	Others
	Ensulizole (2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID) 是磺化的紫外线吸收剂，可以强烈吸收 UVB 和部分 UVA。在紫外线或阳光照射下，它可以产生活性氧，进而破坏 DNA。
T7769	Nonapeptide-1 Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,九胜肽-1,Melanostatine™ 5	Others	Others
	Nonapeptide-1 (Melanostatine™ 5) 可以抑制黑色素的合成，这使得它对治疗某些皮肤病很感兴趣。
T77695	Muvalaplin LY3473329	Others	Others
	Muvalaplin (LY3473329) 是一种具有口服活性的脂蛋白 (a) Lp (a) 抑制剂，可阻断 apo(a)-apo B100 相互作用来抑制 Lp(a) 的形成。
T12652	(Rac)-5-Keto Fluvastatin 5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin	Others	Others
	(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) 是 Fluvastatin 的杂质，Fluvastatin 是一种 HMG-CoA 还原酶的抑制剂。
T1487	Fluvastatin sodium XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Fluvastatin sodium (Fluvastatin sodium salt) salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
T21405	Fluvastatin Canef,XU-62320,Vastin,Cranoc,Lescol	HMG-CoA Reductase	Metabolism
	Fluvastatin (XU-62320) 是一种具有高效性和竞争性的 HMG-CoA 还原酶抑制剂（IC50 ：8 nM），可通过依赖 Nrf2 通路抑制血管平滑肌细胞免受氧化应激，用于降低血浆胆固醇水平和预防心血管疾病。
T38863	Luvadaxistat TAK-831,Luvadaxistat
	TAK-831 is a potent and highly selective inhibitor of D-amino acid oxidase (DAAO), offering great potential for utilization in schizophrenia research.
T2516	Amuvatinib MP470,HPK 56	Apoptosis; FLT; c-Met/HGFR; c-RET; DNA/RNA Synthesis; PDGFR; c-Kit	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors
	Amuvatinib (MP470) 是一种多靶点酪氨酸激酶抑制剂，对突变 c-Kit，PDGFRα，Flt3，c-Met 和 c-Ret 具有活性。它还是一种 DNA 修复抑制剂，靶向蛋白 DNA 修复 RAD51，从而破坏 DNA 损伤修复，具有抗肿瘤活性。
T1510	Rosuvastatin calcium ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂，具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用，还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，延迟心脏复极化，来延长动作电位持续时间和校正 QT 间期间隔。
T11684	Isoguvacine hydrochloride 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride,异四氢烟酸	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) 是 GABA 受体激动剂。它与大鼠突触皮质膜结合并激活 α1β2γ2S、α2β2γ2S、α3β2γ2S、α5β2γ2S 和 ρ1 亚基 GABAA 受体。
T68018	Tuvatexib	VDAC	Membrane transporter/Ion channel
	Tuvatexib 是一种小分子VDAC/HK2双调节剂。
T1676	Rosuvastatin 罗伐他汀,ZD 4522,瑞舒伐他汀	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin (ZD 4522) 是一种抗血脂药，可竞争性抑制羟甲基戊二酰辅酶 A 还原酶，用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，IC50为 195 nM，延迟心脏复极化，延长动作电位持续时间和校正 QT 间期间隔。
T11306	Fluvastatin D6 sodium XU 62-320 (D6)	Others	Others
	Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium.
T10129	(3S,5R)-Fluvastatin sodium (3S,5R)-XU 62-320	Others	Others
	(3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-
T19551	Rosuvastatin D6 Calcium	Others	Others
	Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
TP2121	Sauvagine
	Corticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively.
T78351	Phosphoenolpyruvate carboxylase PEPC
	Phosphoenolpyruvate carboxylase (PEPC) 是将磷酸烯醇丙酮酸同碳酸氢盐在 Mg2+ 存在下以不可逆的过程转变成草酰乙酸和无机磷的二氧化碳固定酶。该酶在催化景天酸代谢植物中二氧化碳(CO(2))的初级同化过程中发挥关键作用，并在植物代谢的昼夜模式设定中扮演主要角色。
T80060	Pyruvate carboxylase	Endogenous Metabolite	Metabolism
	Pyruvate carboxylase是一种催化反应中丙酮酸与HCO3−和MgATP进行依赖性羧化生成草酰乙酸的含生物素酶。它在调控肝脏糖异生、脂肪细胞脂肪酸合成及胰腺β细胞胰岛素分泌方面，对全身能量平衡发挥关键作用。
T125971	Isotriuvaretin
	Isotriuvaretin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125971，CAS号为 137397-72-9。
T34325	Ribuvaptan
	Ribuvaptan is a antagonist of vasopressin receptor .
T10126	(3R,5R)-Rosuvastatin	Others	Others
	(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).
T81257	Rosuvastatin zinc salt Rosuvastatin zinc
	Rosuvastatin zinc salt (Rosuvastatin zinc)，为Rosuvastatin的含锌盐形态，属于HMG-CoA还原酶抑制剂类药物，常用于动脉粥样硬化的研究领域。
T60341	Pyruvate Carboxylase-IN-1
	Pyruvate Carboxylase-IN-1 (compound 37) 是一种有效的丙酮酸羧化酶(PC) 抑制剂，对于基于细胞裂解物和基于细胞的 PC 活性，IC50s 分别为 0.204 和 0.104 μM。Pyruvate Carboxylase-IN-1 是毛兰素的天然类似物。Pyruvate Carboxylase-IN-1 抑制 PC 的酶活性，介导人肝细胞癌 (HCC) 的抗癌作用。
T61154	Colistin adjuvant-2
	Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].
T62125	Colistin adjuvant-1
	Colistin adjuvant-1 是一种粘菌素佐剂 (colistin adjuvant)，对革兰氏阴性细菌具有增强的粘菌素增强活性。Colistin adjuvant-1 对 NF-κB 表现出抑制作用 (IC50: 0.209 μM)。
T124547	Diuvaretin
	Diuvaretin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124547，CAS号为 61463-04-5。
T76143	Pyruvate oxidase
	Pyruvate oxidase(PoxB) 是一种焦磷酸硫胺素依赖型的氧化酶，可以催化丙酮酸氧化脱羧生成乙酰磷酸、二氧化碳和水。Pyruvate oxidase 是细菌代谢中的一种重要酶，常用于生化研究。
T75894	Sauvagine TFA
	Sauvagine TFA，是一种来自青蛙皮肤的 40 个氨基酸的神经肽，是哺乳动物 CRF 激动剂。Sauvagine TFA 可有效从大鼠垂体细胞释放 ACTH。Sauvagine TFA 在利尿，心血管系统和内分泌腺体方面具有许多药理作用。
T69178	Rosuvastatin lactone
	Rosuvastatin lactone is the lactone form of the HMG-CoA reductase inhibitor rosuvastatin. It is found in vivo following rosuvastatin administration. Rosuvastatin lactone is an inhibitor of the cytochrome P450 (CYP) isoforms CYP2C9.1 and CYP2C9.3 (IC50s = 8.52 and 4.1 µM, respectively).
T63430	Rosuvastatin Sodium
	Rosuvastatin Sodium 是竞争性HMG-CoA 还原酶 (HMGCR) 抑制剂 (IC50: 11 nM)，能够有效阻断hERG 电流 (IC50: 195 nM)。Rosuvastatin Sodium 可以有效减少低密度脂蛋白 (LDL) 胆固醇，甘油三酯和 C- 反应蛋白水平。Rosuvastatin Sodium 能够减少成熟 hERG 的表达，并抑制及热休克蛋白 70 (Hsp70) 与 hERG 蛋白的相互作用。
T125561	Uvarigranol E
	Uvarigranol E 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125561。
T69237	Phosphoenol-3-bromopyruvate
	Phosphoenol-3-bromopyruvate is a mechanism-based inhibitor of phosphoenolpyruvate carboxylase from maize
T124682	Uvamalol D
	Uvamalol D 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124682。
TMIH-0242	Fluvastatin-d6 Sodium Salt
	Fluvastatin-d6 Sodium Salt 是 Fluvastatin Sodium Salt 的氘代化合物。Fluvastatin Sodium Salt 的 CAS 号为 93957-55-2。Fluvastatin sodium salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
T10128	(3S,5R)-Fluvastatin D6 sodium (3S,5R)-XU 62-320 D6	Others	Others
	(3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM).
T10338	Antisauvagine-30 TFA (220673-95-0 free base) Antisauvagine-30 TFA,aSvg-30 TFA	Others	Others
	Antisauvagine-30 TFA (aSvg-30 TFA) is a highly selective and competitive antagonist of CRF2 receptor peptidic. It shows a Kd of 1.4 nM and 150 nM for mCRFR2β and CRFR1, respectively.
T77187	Zeluvalimab
	Zeluvalimab (AMG-404) 是一种靶向PD-1受体的单克隆抗体，可用于癌症的研究。
T39036	(3R,5S)-Fluvastatin (3R,5S)-Fluvastatin,(3R,5S)-XU 62-320 free acid
	(3R,5S)-Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.
T80559	Duvakitug
	Duvakitug为针对TNFSF15/TL1A的人源IgG1-λ2型单克隆抗体，在CHOK1SV细胞系的内源性谷氨酰胺合成酶(GS)阳性细胞中表达，适用于克罗恩病（Crohn's Disease, CD）研究。
T12759	Rosuvastatin D6 Sodium	Others	Others
	Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T10131	(3S,5R)-Rosuvastatin	Others	Others
	(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).
T19132	(3R,5R)-Rosuvastatin Lactone	Others	Others
	(3R,5R)-Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone.
TP2091	Antisauvagine-30
	Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells
TMIH-0052	3S,5R-Fluvastatin-d6
	3S,5R-Fluvastatin-d6 是 3S,5R-Fluvastatin 的氘代化合物。3S,5R-Fluvastatin 的 CAS 号为 94061-81-1。
T68381	Tuvatidine
	Tuvatidine is a histamine 2 receptor antagonist.
T61961	Pyruvate Carboxylase-IN-2
	Pyruvate Carboxylase-IN-2 是毛兰素的天然类似物。Pyruvate Carboxylase-IN-2 (compound 29) 是有效的丙酮酸羧化酶(pyruvate carboxylase) 抑制剂。在基于细胞裂解物和基于细胞的 PC 活性中，Pyruvate Carboxylase-IN-2的 IC50s 分别为 0.065 和 0.097 μM。Pyruvate Carboxylase-IN-2介导人肝细胞癌 (HCC) 的抗癌作用。
T70592	Makaluvamine A
	Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.
T39611	Enuvaptan Enuvaptan,BAY-2327949
	Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.
T76115	Pyruvate kinase
	Pyruvate kinase 是一种糖酵解酶，催化磷酸烯醇式丙酮酸和 ADP 转化为丙酮酸和 ATP。

化合物

Cat.No: T9048

Target: Others

Cat.No: T19310

Synonym: 2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID,苯基苯丙咪唑磺酸,2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid,Phenylbenzimidazole sulfonic acid

Target: Others

Cat.No: T7769

Synonym: Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,九胜肽-1,Melanostatine™ 5

Target: Others

Cat.No: T77695

Synonym: LY3473329

Target: Others

(Rac)-5-Keto Fluvastatin

Cat.No: T12652

Synonym: 5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin

Target: Others

Fluvastatin sodium

Cat.No: T1487

Synonym: XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T21405

Synonym: Canef,XU-62320,Vastin,Cranoc,Lescol

Target: HMG-CoA Reductase

Cat.No: T38863

Synonym: TAK-831,Luvadaxistat

Cat.No: T2516

Synonym: MP470,HPK 56

Target: Apoptosis, FLT, c-Met/HGFR, c-RET, DNA/RNA Synthesis, PDGFR, c-Kit

Rosuvastatin calcium

Cat.No: T1510

Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Isoguvacine hydrochloride

Cat.No: T11684

Synonym: 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride,异四氢烟酸

Target: GABA Receptor

Cat.No: T68018

Target: VDAC

Cat.No: T1676

Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Fluvastatin D6 sodium

Cat.No: T11306

Synonym: XU 62-320 (D6)

Target: Others

(3S,5R)-Fluvastatin sodium

Cat.No: T10129

Synonym: (3S,5R)-XU 62-320

Target: Others

Rosuvastatin D6 Calcium

Cat.No: T19551

Target: Others

Cat.No: TP2121

Phosphoenolpyruvate carboxylase

Cat.No: T78351

Synonym: PEPC

Pyruvate carboxylase

Cat.No: T80060

Target: Endogenous Metabolite

Cat.No: T125971

Cat.No: T34325

(3R,5R)-Rosuvastatin

Cat.No: T10126

Target: Others

Rosuvastatin zinc salt

Cat.No: T81257

Synonym: Rosuvastatin zinc

Pyruvate Carboxylase-IN-1

Cat.No: T60341

Colistin adjuvant-2

Cat.No: T61154

Colistin adjuvant-1

Cat.No: T62125

Cat.No: T124547

Pyruvate oxidase

Cat.No: T76143

Cat.No: T75894

Rosuvastatin lactone

Cat.No: T69178

Rosuvastatin Sodium

Cat.No: T63430

Uvarigranol E

Cat.No: T125561

Phosphoenol-3-bromopyruvate

Cat.No: T69237

Cat.No: T124682

Fluvastatin-d6 Sodium Salt

Cat.No: TMIH-0242

(3S,5R)-Fluvastatin D6 sodium

Cat.No: T10128

Synonym: (3S,5R)-XU 62-320 D6

Target: Others

Antisauvagine-30 TFA (220673-95-0 free base)

Cat.No: T10338

Synonym: Antisauvagine-30 TFA,aSvg-30 TFA

Target: Others

Cat.No: T77187

(3R,5S)-Fluvastatin

Cat.No: T39036

Synonym: (3R,5S)-Fluvastatin,(3R,5S)-XU 62-320 free acid

Cat.No: T80559

Rosuvastatin D6 Sodium

Cat.No: T12759

Target: Others

(3S,5R)-Rosuvastatin

Cat.No: T10131

Target: Others

(3R,5R)-Rosuvastatin Lactone

Cat.No: T19132

Target: Others

Antisauvagine-30

Cat.No: TP2091

3S,5R-Fluvastatin-d6

Cat.No: TMIH-0052

Cat.No: T68381

Pyruvate Carboxylase-IN-2

Cat.No: T61961

Cat.No: T70592

Cat.No: T39611

Synonym: Enuvaptan,BAY-2327949

Pyruvate kinase

Cat.No: T76115

Cat. No.	Product Name	Target	Signaling Pathways
T0473	Arbutin Uva,p-Arbutin,p-Arbutin,熊果苷,β-Arbutin	Tyrosinase	Proteases/Proteasome
	Arbutin (p-Arbutin) 是一种从熊果植物 Arctostaphylos uvaursi 中分离出的天然多酚，具有抗氧化，抗炎和抗肿瘤特性。它是一种脱色剂，也是一种黑色素细胞中酪氨酸酶的竞争性抑制剂，对单酚酶的 Kiapp 值为 1.42 mM；对二酚酶Kiapp 的值为 0.9 mM。
T4891	Sodium phenylpyruvate 苯丙酮酸钠,Phenylpyruvic acid, sodium salt	Others	Others
	Sodium phenylpyruvate (Phenylpyruvic acid, sodium salt) 是phenylpyruvate decarboxylase 和phenylpyruvate tautomerase 互变异构酶的底物。
T7557	Guvacine hydrochloride	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Guvacine hydrochloride 是从槟榔中得到的一种生物碱，是 GABA 摄取抑制剂，IC50为 10 μM。它对几种克隆的 GABA 转运体具有适度的选择性。
T8030	Ethyl pyruvate	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Ethyl pyruvate 是一种内源性代谢物丙酮酸的衍生物，是一种抗炎剂。
T5805	Guvacoline hydrochloride 1,2,5,6-四氢吡啶-3-甲酸甲酯盐酸盐,Norarecoline hydrochloride,去甲槟榔碱	AChR	Neuroscience
	Guvacoline hydrochloride (Norarecoline hydrochloride) 是从三药槟榔中发现的一种吡啶生物碱，可作为心房和回肠的毒蕈碱激动剂。
TN2290	Uvaol	Endogenous Metabolite; JNK; PPAR	DNA Damage/DNA Repair; MAPK; Metabolism
	Uvaol 存在于橄榄和初榨橄榄油中，具有抗炎、抗增殖和血管舒张活性。
TN1717	Guvacine	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Guvacine can enhance the inhibition of spinal neurones by GABA.
T80014	Guvacine hydrobromide	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Guvacine hydrobromide为槟榔中提取的生物碱，具有作为GABA摄取抑制剂的活性。该化合物对大鼠GAT-1、GAT-2和GAT-3的GABA摄取抑制作用具有不同的IC50值，分别为39 μM、58 μM及378 μM。
TN3824	Demethylluvangetin	Others	Others
	Demethylluvangetin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3824，CAS号为 64652-10-4。
TN6381	Grandiuvarin A
	Grandiuvarin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6381，CAS号为 882692-93-5。
TN4465	Luvangetin	COX; Prostaglandin Receptor; Antifection	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection against pylorus-ligated and aspirin-induced gastric ulcers in rats and cold restraint stress-induced
TN2292	Uvarigranol C	Others	Others
	Uvarigranol C is a natural product
T80887	Uvaol diacetate
	Uvaol diacetate (Compound 5)，一种从Nerium oleander L.叶提取的三萜化合物。
TJS0123	Guvacine ethyl ester 槟榔碱,PT00442-2	Others	Others
	Guvacine ethyl ester (Arecoline) 是一种生物碱，存在于槟榔中，可用于 GABA 摄取抑制剂的合成。
T40695	Isouvaretin
	Isouvaretin demonstrates potent antibacterial activity against B. subtilis and S. epidermidis.
TN2291	Uvarigranol B	Others	Others
	Uvarigranol B is a natural product
T80886	Uvariol 21-Hydroxylanosterol
	Uvariol (21-Hydroxylanosterol)为一自Piptostigma fugax根部提取得到的天然化合物。
T32326	Juvabione
	Juvabione is the methyl ester of todomatuic acid, both of which are sesquiterpenes (C15) found in the wood of true firs of the genus Abies. They exist as part of a mixture of sesquiterpenes based on the bisabolane scaffold. Sesquiterpenes of this family,
T40665	Uvaretin
	Uvaretin demonstrates potent antibacterial activity against B. subtilis (EC50: 8.7 μM) and S. epidermidis (IC50: 7.9 μM).
T13956	Uvarigrin	Others	Others
	Uvarigrin induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation. Uvarigrin is isolated from the roots of Uvaria calamistrata.
TN7117	regaloside I	Others	Others
	Regaloside I 是百合中的单体成分,可能是保护人类皮肤成纤维细胞免受 UVA 诱导的形态变化的主要成分。
TN6988	Pterine-6-carboxylic acid 6-Carboxypterin	DNA; PDE	DNA Damage/DNA Repair; Metabolism
	Pterine-6-carboxylic acid (6-Carboxypterin) 是叶酸的光降解产物，可被用作光敏感剂研究UVA 破环DNA 结构的分子机制。
TN1060	Ganoderol A 灵芝醇 A,灵芝醇A	Others	Others
	Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis.
TN1542	Cycloheterophyllin	NADPH-oxidase; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Tyrosine Kinase/Adaptors
	Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be used in the research on and prevention of skin photoaging.

天然产物

Cat.No: T0473

Synonym: Uva,p-Arbutin,p-Arbutin,熊果苷,β-Arbutin

Target: Tyrosinase

Sodium phenylpyruvate

Cat.No: T4891

Synonym: 苯丙酮酸钠,Phenylpyruvic acid, sodium salt

Target: Others

Guvacine hydrochloride

Cat.No: T7557

Target: GABA Receptor

Cat.No: T8030

Target: Apoptosis, Antioxidant

Guvacoline hydrochloride

Cat.No: T5805

Synonym: 1,2,5,6-四氢吡啶-3-甲酸甲酯盐酸盐,Norarecoline hydrochloride,去甲槟榔碱

Target: AChR

Cat.No: TN2290

Target: Endogenous Metabolite, JNK, PPAR

Cat.No: TN1717

Target: GABA Receptor

Guvacine hydrobromide

Cat.No: T80014

Target: GABA Receptor

Demethylluvangetin

Cat.No: TN3824

Target: Others

Cat.No: TN6381

Cat.No: TN4465

Target: COX, Prostaglandin Receptor, Antifection

Uvarigranol C

Cat.No: TN2292

Target: Others

Uvaol diacetate

Cat.No: T80887

Guvacine ethyl ester

Cat.No: TJS0123

Synonym: 槟榔碱,PT00442-2

Target: Others

Cat.No: T40695

Uvarigranol B

Cat.No: TN2291

Target: Others

Cat.No: T80886

Synonym: 21-Hydroxylanosterol

Cat.No: T32326

Cat.No: T40665

Cat.No: T13956

Target: Others

Cat.No: TN7117

Target: Others

Pterine-6-carboxylic acid

Cat.No: TN6988

Synonym: 6-Carboxypterin

Target: DNA, PDE

Cat.No: TN1060

Synonym: 灵芝醇 A,灵芝醇A

Target: Others

Cycloheterophyllin

Cat.No: TN1542

Target: NADPH-oxidase, PKA, PKC

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