449
74
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36879L |
H-Leu-Leu-OMe . HBr
H-Leu-Leu-OMe . HBr (16689-14-8 Free base) |
Others | Others |
H-Leu-Leu-OMe . HBr 是由人单核细胞或多形核白细胞产生的L-亮氨酸甲酯的二肽缩合产物。 H-Leu-Leu-OMe . HBr 诱导内溶酶体途径应激并选择性地消除具有细胞毒性潜力的淋巴细胞。 | |||
T7739 |
L-Leucyl-L-Leucine methyl ester hydrochloride
Leu-Leu-ome hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) 是一种人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物,能够选择性消除具有细胞毒性潜能的淋巴细胞,也能够诱导溶酶体途径应激。 | |||
TP1212 |
N-Boc-Phe-Leu-Phe-Leu-Phe
Boc-FLFLF |
Others | Others |
N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) 是甲酰肽受体 1(FPR1)拮抗剂,能够增加疼痛作用,抑制膜联蛋白的抗疼痛活性。 | |||
TP1164 |
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA
For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA) |
Others | Others |
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA)) (71901-21-8 free base) 是一种甲酰肽受体 (FPR) 激动剂 。人类中性粒细胞。放射性碘化分子具有充分的生物活性。 | |||
T36352 |
Suc-Leu-Tyr-AMC
|
||
Suc-Leu-Tyr-AMC 是钙蛋白酶 I 和 II 以及木瓜蛋白酶(另一种半胱氨酸蛋白酶)的荧光底物,用于测量 20S 蛋白酶体的糜蛋白酶样肽酶活性(Ex-max:360 nm;Em-max:460 nm)。Suc-Leu-Tyr-AMC 也能被大肠杆菌的 Ti 蛋白酶裂解。 | |||
T22752L |
(D-Ser2)-Leu-Enkephalin-Thr
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
(D-Ser2)-Leu-Enkephalin-Thr 是阿片受体的 delta 选择性药物,具有镇痛作用。 | |||
T7665 |
[Leu5]-Enkephalin TFA(58822-25-6(free bas))
Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin |
Opioid Receptor; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience |
[Leu5]-Enkephalin TFA(58822-25-6(free bas)) (Leucyl-enkephalin) 是最有效的 δ 受体。 | |||
TP1399 |
Fmoc-N-Me-Leu-OH
|
Others | Others |
Fmoc-N-Me-Leu-OH 是 N-Fmoc-N-甲基氨基酸的一种,能够用于肽偶联反应。 | |||
T8557 |
N-terminally acetylated Leu-enkephalin
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
N-terminally acetylated Leu-enkephalin 是一种五氨基酸内源性肽,可作为阿片受体激动剂。N-末端乙酰化 Leu-脑啡肽是 Leu-脑啡肽的 N-末端乙酰化形式。 | |||
TP1168 |
N-Formyl-Met-Leu-Phe-Lys
fMLFK |
Others | Others |
N-Formyl-Met-Leu-Phe-Lys (fMLFK) 是一种多肽,是选择性FPR1激动剂,作用于 FPR1(IC50:3.5 nM),FPR2(IC50:6.7 nM) 和 FPR2-D2817.32G(IC50:0.88 nM) 。 | |||
T7091 |
N-Formyl-Met-Leu-Phe
fMLP,N-Formyl-MLF |
TNF | Apoptosis |
N-Formyl-Met-Leu-Phe (N-Formyl-MLF) 是一种趋化肽和N-甲酰基肽受体的特异性配体,可抑制TNF-alpha 的分泌。 | |||
T2154 |
MG-132
Z-LLL-al,Z-Leu-Leu-Leu-CHO |
Apoptosis; Proteasome; Autophagy | Apoptosis; Autophagy; Proteases/Proteasome; Ubiquitination |
MG-132 (Z-Leu-Leu-Leu-al) 是一种 26S 蛋白酶体抑制剂 (IC50=100 nM),具有细胞渗透性、可逆性。MG-132 可作为自噬激活剂,可诱导凋亡。 | |||
TP2206 |
[Leu31,Pro34]-Neuropeptide Y (porcine)
LEU 31, PRO34]-神经肽Y(猪) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
[Leu31,Pro34]- Neuropeptide Y (porcine) 是神经肽 Y (NPY) 的一种类似物,是对NPY Y1受体有选择性的激动作用。它表现出抗焦虑作用。 | |||
T80665 |
Leu-Val
L-leucyl-L-valine |
Parasite; Antifungal | Microbiology/Virology |
Leu-Val (L-leucyl-L-valine) 是一种新型有效的二肽,具有抗菌和抗疟活性。 | |||
TP2305 |
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val
|
Others | Others |
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val 是一种肽。 | |||
TP2507 |
Leu-Tyr-Asp-Lys
|
||
Leu-Tyr-Asp-Lys 是一种四肽化合物,可用于研究与代谢相关的疾病。 | |||
T40768 |
{Boc}-Phe-Leu-Phe-Leu-Phe
|
||
{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a selective antagonist of the formyl peptide receptor (FPR) family, effectively inhibiting receptor activity in response to formyl peptides. | |||
T12628 |
(R)-MG-132
(S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al |
Proteasome | Proteases/Proteasome; Ubiquitination |
(R)-MG-132 (Z-Leu-D-leu-leu-al) 是一种 MG-132 的对映异构体,是一种蛋白酶体 (proteasome) 抑制剂,细胞毒性比 MG-132 弱,是一种比 MG-132 更有效的proteasome 抑制剂。 | |||
T7536 | H-Leu-Leu-Ome.HCl | Others | Others |
H-Leu-Leu-Ome.HCl 又称Stearamidoethyl diethylamine(SDEA)是一种重要的化合物,它是二乙胺的衍生物,广泛用于各种产品的研究和生产,包括用作化妆品中的表面活性剂、食品中的乳化剂和聚合物中的稳定剂。 | |||
T36352L |
Suc-Leu-Tyr-AMC Acetate
Suc-Leu-Tyr-AMC Acetate(94367-20-1 Free base) |
Others | Others |
Suc-Leu-Tyr-AMC Acetate 在高浓度时抑制酪蛋白分解。 | |||
T7173 |
[Leu5]-Enkephalin
亮氨酸脑啡肽,Leucine enkephalin,Leucyl-enkephalin,Leu-enkephalin |
Opioid Receptor; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience |
[Leu5]-Enkephalin (Leu-enkephalin) 是一种参与伤害感受的内源性神经肽,是 δ-阿片和 μ-阿片受体的激动剂,Ki 值分别为 4.0 和 3.4 nM | |||
T32683 |
Leu-phalloidin
|
||
Leu-phalloidin is a phallotoxin. | |||
TP1252 |
N-terminally acetylated Leu-enkephalin acetate
Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH,N-terminally acetylated Leu-enkephalin |
||
N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. | |||
T11840 |
Leu-AMS
|
Others | Others |
Leu-AMS, a leucine analogue and potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, exhibits cytotoxic effects in both cancer and normal cells and hampers bacterial growth. It specifically inhibits LRS's catalytic activity without impacting the leucine-induced activation of mTORC1. | |||
TP1308 |
Suc-Leu-Leu-Val-Tyr-AMC
|
||
Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases. | |||
T125115 |
Cyclo(L-Leu-L-Pro)
|
Antifungal | Microbiology/Virology |
Cyclo(L-Leu-L-Pro) 是一种来自芝麻假单胞菌BC42的化合物,具有抗真菌活性,抑制真菌病原体,抑制黄曲霉增殖。Cyclo(L-Leu-L-Pro) 抑制分生孢子的萌发和分生孢子的形成,可用于农业生物防治。 | |||
T31631 |
Enkephalin-leu, ala(2)-ser(6)-
DALES,2-Ala-6-ser-leu-enkephalin |
||
Enkephalin-leu, ala(2)-ser(6)- is an active compound at the delta (non-complexed) opioid receptor. | |||
T7173L |
[Leu5]-Enkephalin acetate(58822-25-6 free base)
亮氨酸脑啡肽,Leucine enkephalin,Leu-enkephalin,Leucyl-enkephalin |
Opioid Receptor; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience |
[Leu5]-Enkephalin acetate(58822-25-6 free base) 是一种参与伤害感受的内源性神经肽,是 δ-opioid 和 μ-opioid 受体的激动剂(Kis 分别为 4.0 和 3.4 nM) | |||
TQ0143 |
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys
For-Nle-Leu-Phe-Nle-Tyr-Lys-OH |
Others | Others |
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA is a formyl peptide receptor (FPR) agonist. | |||
T36224 |
N-Hippuryl-His-Leu (hydrate)
|
||
N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors., | |||
T22962 |
Mca-Pro-Leu-NH2
|
Others | Others |
Substrate of matrix metalloproteinases assay | |||
TP1368 |
Ac-Leu-Arg-AMC
|
||
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate. | |||
T18309 |
Mc-Leu-Gly-Arg
|
Others | Others |
Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design. | |||
TP2309 |
NEUROTENSIN TFA (39379-15-2 free base)
Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA(55508-42-4 free base),NEUROTENSIN TFA,神经加压素 |
Others | Others |
Neurotensin TFA (39379-15-2 free base) 是一种内源性 13 个氨基酸的神经肽,具有显着的阿片类非依赖性镇痛作用。它在大脑中充当神经递质,在肠道中充当激素,也充当神经调节剂。由于它与多种神经递质系统如多巴胺能、血清素能、谷氨酸能、GABA 能和胆碱能系统。它具有作为人体代谢物、有丝分裂原、神经递质和创伤的作用。 | |||
T11841 |
Leu-AMS R enantiomer
|
Others | Others |
Leu-AMS R enantiomer 是 Leu-AMS 的 R 对映体。 Leu-AMS 是一种有效的亮氨酰-tRNA 合成酶 (LRS) 抑制剂,可抑制细菌的生长。 | |||
T38130 |
Z-LVG-CHN2
Z-Leu-Val-Gly-diazomethylketone |
||
The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain. | |||
TP1113L |
[Leu5]-Enkephalin, amide acetate
[Leu5]-Enkephalin, amide acetate(60117-24-0 free base) |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
[Leu5]-Enkephalin, amide acetate 是一种 δ 阿片受体激动剂。 | |||
T80542 |
Z-Leu-Leu-Leu-fluoromethyl ketone
Z-LLL-FMK |
||
Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK)为半胱氨酸蛋白酶抑制剂,可抑制SARS感染,并能保护小鼠免遭T. crassiceps侵害。 | |||
TP2169 |
Boc-Leu-Gly-Arg-AMC
|
Others | Others |
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate of the convertases used in enzymatic assays. | |||
T76364 |
Ac-Leu-Leu-Norleucinol
|
||
Ac-Leu-Leu-Norleucinol 是钙蛋白酶抑制剂,可用于研究对 Acetaminophen 引起的急性肝损伤,并能够降低诱导引发的谷草转氨酶 (ALT) 和谷丙转氨酶 (AST) 水平。 | |||
TP2346 |
Peptide 399
(Leu-lys-lys-leu-leu-lys-leu)2 |
||
Peptide 399 is an antimicrobial peptide with an idealized amphiphilic alpha helix. | |||
T40415 |
Fmoc-Leu-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Leu-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T83690 |
[Leu144, Arg147]-PLP (139-151) TFA
[Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH |
||
[Leu144,Arg147]-PLP (139-151)是髓鞘脂蛋白(PLP)的一种突变肽段,包含位于144和147位置的色氨酸到亮氨酸以及组氨酸到精氨酸的替换。使用[Leu144, Arg147]-PLP (139-151)(50 µg)乳化于完全弗氏佐剂(CFA)免疫后,能增加小鼠脾脏中的IL-4水平。它在体外抑制Th1细胞激活,但在体内不抑制,其中它诱导调节性T细胞的产生。用[Leu144, Arg147]-PLP (139-151)预免疫可以延迟由脑炎肽PLP (178-191)、髓磷脂少突细胞蛋白(MOG) (92-106)或髓鞘基础蛋白(MBP)在小鼠中诱导的实验性自身免疫性脑炎(EAE)的发病。 | |||
T82191 |
H-Leu-Leu-Ala-OH
|
||
H-Leu-Leu-Ala-OH,一种三肽,由两个L-亮氨酸单元通过肽键与一个L-丙氨酸单元连接,具备抗氧化活性。 | |||
T80102 |
Z-Leu-Leu-Tyr-COCHO
|
Proteasome | Proteases/Proteasome; Ubiquitination |
Z-Leu-Leu-Tyr-COCHO为胰凝乳蛋白酶样活性抑制剂,具有Ki值为3.0 nM的高效性。 | |||
T18708 |
SPDP-C6-Gly-Leu-NHS ester
|
Others | Others |
SPDP-C6-Gly-Leu-NHS ester is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T41111 |
Fmoc-Leu-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Leu-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T83741 |
S7 TFA
Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH |
||
S7是一种IL-6受体的肽类拮抗剂,能够浓度依赖性地抑制IL-6与IL-6受体的结合。在C-33 A宫颈癌细胞和RPMI-8226 B细胞淋巴细胞中,S7 (50 µM) 能抑制IL-6诱导的VEGF水平增加。在每两天给药一次,剂量为50 mg/kg的条件下,S7能减少IL-6过表达的C-33 A宫颈癌小鼠异种移植模型中的肿瘤体积。当S7与半胱氨酸结合,并连接到包裹多柔比星的脂质纳米粒子(LNPs)表面时,能增强LNPs对胶质瘤的靶向性,并在U251胶质母细胞瘤小鼠异种移植模型中提高生存率。 | |||
T17281 |
Z-Ile-Leu-aldehyde
Z-IL-CHO,GSI-XII,γ-Secretase inhibitor XII |
Others | Others |
Z-Ile-Leu-aldehyde is an effective and competitive peptide aldehyde inhibitor of γ-secretase and notch. | |||
T32675 |
Leucyl-leucyl-tyrosine
L-Leu-L-leu-L-tyr |
||
Leucyl-leucyl-tyrosine is a bioactive chemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMA2613 |
Cyclo(Pro-Leu)
Cyclo-L-leu-L-pro,Cyclo-L-prolyl-L-leucine,Cyclo(leucyloprolyl) |
Others | Others |
Cyclo(Pro-Leu) (Cyclo-L-prolyl-L-leucine) 是一种源自海洋的天然产物,具有盐水虾的杀伤力。 | |||
TN6444 |
Cyclo(Tyr-Leu)
|
Antifungal | Microbiology/Virology |
Cyclo(Tyr-Leu) 是一种来自马齿苋 Portulaca oleracea Linn 的环状二肽,具有细胞毒性、抗真菌和抗凝血活性。 | |||
TN6681 |
Cyclo(Leu-Leu)
|
||
Cyclo(Leu-Leu) is an efficient supramolecular catalyst. | |||
T4086 |
Glycyl-L-leucine
甘氨酰-L-亮氨酸,Gly-Leu |
Others | Others |
Glycyl-L-leucine (Gly-Leu) 是一种可用作糖基亮氨酸二肽酶底物的二肽。 | |||
T3O2749 |
L-Leucine
(S)-Leucine,Leu,L-亮氨酸,亮氨酸 |
mTOR | PI3K/Akt/mTOR signaling |
L-Leucine ((S)-Leucine) 是必需的支链氨基酸,能够激活 mTOR 信号通路。 | |||
TN6676 |
Cyclo(Ile-Leu)
|
||
Cyclo(Ile-Leu) shows cytotoxic activity in vitro. | |||
TN6447 | Cyclo(Leu-Val) | ||
Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain. | |||
TN6680 |
Cyclo(Hpro-Leu)
|
||
Cyclo(Hpro-Leu) 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6680,CAS号为 1016899-93-6。 | |||
TMA2620 |
Cyclo(Leu-Ala)
|
Others | Others |
Cyclo(Leu-Ala) is the Diketopiperazine. | |||
TN6430 | Cyclo(Phe-Leu) | ||
Cyclo(Phe-Leu) is a new cell cycle inhibitor. | |||
T65240 |
Leu-Leu-OH
|
||
Leu-Leu-OH 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T65240,CAS号为 3303-31-9。 | |||
TN6043 |
Cyclo(D-Leu-L-Pro)
|
||
Cyclo(D-Leu-L-Pro) shows antitumour and antifungal activities. | |||
TN6671 | Cyclo(L-Leu-trans-4-hydroxy-L-Pro) | ||
Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural product from Phellinus igniarius. | |||
T34931 |
Trichodecenin II
Trichodecenin-II,4-Decenoyl-gly-gly-leu-aib-gly-leu-lol |
||
Trichodecenin II is a peptaibol isolated from Trichoderma viride. | |||
T79972 |
Cyclo(L-leucyl-L-valyl)
|
Antifungal | Microbiology/Virology |
Cyclo(L-leucyl-L-valyl) 是从昆明链霉菌 YIM 次级代谢产物中部分离得到的多要化合物,尚未显示出抗菌活性。 | |||
T3662 |
Eleutheroside E
|
NF-κB | NF-κB |
Eleutheroside E 是刺五加的重要成分,具有抗炎,保护缺血心脏的功能。 | |||
T4798 |
N-Acetyl-L-leucine
|
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-L-leucine 是内源性代谢产物的一种。 | |||
T6917 |
Oleuropein
洋橄榄苦甙,橄榄苦苷 |
Apoptosis; Aromatase; ROS; PPAR | Apoptosis; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism |
Oleuropein 在橄榄叶和油中发现的天然产物,通过 p53 依赖性途径以及 Bax 和 Bcl2基因的调控来诱导乳腺癌细胞凋亡,还抑制芳香化酶。它可通过直接抑制 PPARγ转录活性来发挥抗氧化,抗炎和抗动脉粥样硬化作用。 | |||
T0063 |
L-Isoleucine
异亮氨酸,isoleucine,Ile,L-异亮氨酸 |
Amino Acids and Derivatives; Endogenous Metabolite | Metabolism |
L-Isoleucine (Ile) 是一种非极性疏水性氨基酸。它是必需氨基酸。 | |||
T4765 |
L-Norleucine
(S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid,L-2-氨基己酸 |
Influenza Virus; Endogenous Metabolite | Metabolism; Microbiology/Virology |
L-Norleucine ((S)-Norleucine) 是亮氨酸的异构体,特异性影响骨骼肌中的蛋白质合成,具有抗病毒活性。 | |||
T9143 |
D-Isoleucine
(2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine |
Others | Others |
D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) 是一种异亮氨酸立体异构体,是 Asc-1 反转运蛋白的选择性激活剂。它能够释放内源性 D-丝氨酸,提高海马 CA1-CA3 的长期增效作用。 | |||
T7448 |
4-Hydroxyisoleucine
4-羟基-L-异亮氨酸,4-Hydroxy-L-isoleucine |
Others | Others |
4-Hydroxyisoleucine (4-Hydroxy-L-isoleucine) 是从胡芦巴种子中提取和纯化的一种氨基酸,具有促胰岛素作用。 | |||
T4772 |
(±)-Leucine
DL-Leucine,(+/-)-Amino-4-methylpentanoic acid,DL-亮氨酸,DL-2-Aminmo-4-methylvalerianic acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
(±)-Leucine (DL-2-Aminmo-4-methylvalerianic acid) 是亮氨酸的异构体,是一种化学杀菌剂和膳食添加剂,存在于青椒、青西葫芦、意大利甜红辣椒和红甜椒中。 | |||
T5294 |
(S)-Leucic acid
L-alpha-羟基异己酸,L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-2-羟基-4-甲基戊酸,(S)-(−)-2-Hydroxyisocaproic acid |
Others; Endogenous Metabolite | Metabolism; Others |
(S)-Leucic acid (Hydroxyisocaproic acid) 是氨基酸代谢物。 | |||
T9299 |
D-Leucine
D-亮氨酸,(R)-Leucine |
Endogenous Metabolite | Metabolism |
D-Leucine ((R)-Leucine) 具有抗癫痫特性,活性比L-leucine,能够有效终止癫痫发作。在体外,它能够抑制长期点位,但基底突触传递无影响。 | |||
T16552 |
Pleuromutilin
Mutilin 14-glycolate,Drosophilin B,截短侧耳素 |
Antibacterial; Antibiotic | Microbiology/Virology |
Pleuromutilin (Drosophilin B) 通过与细菌的 50S 核糖体亚基结合来抑制细菌蛋白质的合成。 | |||
T6431 |
Levoleucovorin Calcium
左亚叶酸钙,Calcium Levofolinate,CL307782 |
Others; Antifolate | Cell Cycle/Checkpoint; Others |
Levoleucovorin Calcium (CL307782) 是一种亚叶酸的钙盐,在癌症化疗中用作辅助剂。 | |||
T2P2919 |
(2S,3R,4S)-4-Hydroxyisoleucine
(4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine |
PI3K | PI3K/Akt/mTOR signaling |
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分,具有抗糖尿病、抗糖尿病肾病的作用。 | |||
T3607 |
Leucomycin
吉他霉素,Kitasamycin,Leucomycin V,Turimycin |
Antibacterial; Antibiotic | Microbiology/Virology |
Leucomycin (Turimycin) 是一种由 Streptomyces kitasatoensis 产生的大环内酯类抗生素。 | |||
T5219 |
L-Alloisoleucine
L-别异亮氨酸,L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine |
Others; Endogenous Metabolite | Metabolism; Others |
L-Alloisoleucine (L-allo-Isoleucine) 是 L-异亮氨酸的立体异构体,是一种支链氨基酸,是人血浆的常见成分 (尽管水平较低)。 | |||
T12297 |
Oleuropeinic acid
|
Others | Others |
Oleuropeinic acid 是一种抗氧化剂可溶性纤维,存在于橄榄组织中或通过热处理形成,可能是由橄榄苦苷的氧化形成。 | |||
T6564 |
Leupeptin Hemisulfate
亮肽素 |
Serine Protease; Cysteine Protease | Proteases/Proteasome |
Leupeptin hemisulfate 是一种蛋白酶抑制剂,具有细胞膜渗透性、可逆性、竞争性和口服活性。Leupeptin hemisulfate 可以抑制 Cathepsin B、Cathepsin H、Cathepsin L 的活性,阻断两性溶酶体的融合。Leupeptin hemisulfate 还具有抗炎活性。 | |||
TN2331 |
Eleutheroside B1
刺五加苷B1 |
Influenza Virus | Microbiology/Virology |
Eleutheroside B1是具有广谱抗人流感病毒的一种香豆素。它抑制多种趋化因子基因和流感病毒核蛋白基因的 mRNA 表达。它具有抗病毒、抗流感和抗炎活性,且细胞毒性小。 | |||
T8373 |
6-Diazo-5-oxo-L-nor-Leucine
DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine |
Influenza Virus; Glutaminase; Antibacterial; Antibiotic | Microbiology/Virology; Proteases/Proteasome |
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) 是一种谷氨酰胺拮抗剂,具有抗菌、抗病毒和抗癌作用,其Ki 值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力 ,在体外表现出遗传毒性。 | |||
T2886 |
Aleuritic Acid
9,10,16-trihydroxy-palmitic acid,Aleuritolic acid,紫胶酮酸,紫胶桐酸 |
Others | Others |
Aleuritic Acid (9,10,16-trihydroxy-palmitic acid) 是紫胶中的一种主要成分,可用于香料工业。 | |||
T3S1390 |
Leucoside
堪非醇3-O-桑布双糖苷,Kaempferol 3-sambubioside,Kaempferol 3-O-sambubioside |
Others | Others |
Leucoside (Kaempferol 3-sambubioside) 是一种天然产物,分离自茶籽提取物。 | |||
TN3503 | Beta-Furoyleupatolide | Others | Others |
Beta-Furoyleupatolide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3503,CAS号为 114437-24-0。 | |||
T4S0280 | Eleutheroside D | ||
Eleutheroside has protective effect to myocardial ischemic-reperfusion injury(IRI) in isolated rats. | |||
TN2339 |
Eleutherol
红葱甲素,红葱酚 |
Others | Others |
Eleutherol Derived from Eleutherine plicata. | |||
TN2375 |
Isoeleutherin
|
Others | Others |
Isoeleutherin Has anti-cancer and anti-inflammatory effects. | |||
TN2667 |
1beta,10beta-Epoxydehydroleucodin
|
Others | Others |
1beta,10beta-Epoxydehydroleucodin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2667,CAS号为 130858-00-3。 | |||
T19496 |
Oleuroside
|
Others | Others |
Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. | |||
T81221 |
Salvileucalin A
|
||
Salvileucalin A是一种新型氯烷类二萜化合物,从鼠尾草(Salvia spp.)的地上部分提取。 | |||
TN4558 |
Methyleugenolglycol
|
Others | Others |
Methyleugenolglycol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4558,CAS号为 26509-45-5。 | |||
TN4429 |
Leucodin
|
MMP; TNF | Apoptosis; Proteases/Proteasome |
Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosaminidase release from RBL-2H3 cells in a dose-dependent manner with IC50 of 80 microM. | |||
TN3780 | Deacetyleupaserrin | Others | Others |
Deacetyleupaserrin is an antileukemic sesquiterpene lactone. | |||
TN2464 |
Eleutherin
|
Topoisomerase | DNA Damage/DNA Repair |
Eleutherin is a natural product from Eleutherine americana | |||
T81220 |
Salvileucantholide
|
||
Salvileucantholide为一种从S. leucantha中提取的二萜类化合物。 | |||
T29477 |
6R-Leucovorin
(6R,2'S)-Folinic acid,Dextrofolinic acid |
||
6R-Leucovorin is a derivative of Folic Acid. | |||
TN4431 |
Leucosceptoside A
|
RAAS; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones |
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE) | |||
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