36
17
1748
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10503 |
ACAT-IN-1 cis isomer
|
Acyltransferase | Metabolism |
ACAT-IN-1 cis isomer是一种有效的 ACAT 抑制剂(IC50:100 nM),可用于研究免疫系统相关疾病。 | |||
T3470 |
Cis-ACBD
cis-1-aminocyclobutane-1,3-dicarboxylic acid,氨基二羧酸 |
Amino Acids and Derivatives | Metabolism |
Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) 是一种有效的选择性 N-甲基-D-天冬氨酸受体激动剂。 | |||
T41200 |
cis MZ 1
|
||
cis MZ 1 is a negative Control for MZ1. Exhibits no significant VHL binding affinity. | |||
T66121 |
Ketoconazole Intermediate 1e
(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate |
Others | Others |
Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate) 是一种酮康唑中间体。 | |||
T41199 |
cis-SIM1
cis-SIM1 |
||
cis-SIM1 is the negative control for SIM1. | |||
T19089 |
(Z)-Viaminate
Ethyl 4-((2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido)benzoate |
Others | Others |
(Z)-Viaminate is a derivative of Retinoic acid. | |||
TNU0688 |
cis-1-Benzyl-4-(methoxycarbonyl)pyrrolidine-3-carboxylic acid
|
||
cis-1-Benzyl-4-(methoxycarbonyl)pyrrolidine-3-carboxylic acid is a Other heterocyclic compound - pyrrolidine, building block - electrophile. | |||
T77505 |
Chloroallyl methenamine chloride
Quaternium-15 cis-form |
||
cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) 是一种抗菌剂,用于化妆品中作为化妆品防腐剂和抗静电剂。cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride 是一种口服致畸剂,但不是皮肤致畸剂,在大鼠中剂量超过了化妆品的预期累积暴露量。 | |||
T13037 |
Sulindac sulfide
cis-Sulindac sulfide |
Raf; Others; AChR | MAPK; Neuroscience; Others |
Sulindac sulfide (cis-Sulindac sulfide) 是一种非甾体抗炎化合物,对COX-1具有很高的亲和力,是Ras 激活Raf-1的抑制剂。Sulindac sulfide 是 γ-secretase 的一个非竞争性抑制剂, IC50 为 20.2 μM。它是舒林酸的活性代谢物。 | |||
T16538 |
PIN1 inhibitor API-1
|
Others | Others |
PIN1 inhibitor API-1 是特殊的 Pin1抑制剂,可直接特异性地与 Pin1 肽基脯氨酰异构酶结构域结合,并抑制 Pin1 顺反异构活性。它保留 pXPO5 的活性构象,恢复 pXPO5 将前 miRNA 从细胞核转运到细胞质的能力,从而上调抗癌 miRNA 的生物发生,抑制体内外肝癌的发生。 | |||
T74451 |
13-cis-Retinyl acetate
|
||
13-cis-Retinyl acetate (13-cis-Retinol acetate; 13-cis-Vitamin A acetate),视黄醇乙酸酯的13-顺式异构体,是维生素A的一个活性代谢物。 | |||
T82717 |
cis-Indatraline hydrochloride
cis-Lu 19-005 |
||
cis-Indatraline (cis-Lu 19-005) hydrochloride 是一款用于神经退行性疾病研究的活性化合物。 | |||
T13524 |
9-cis-β-Carotene
|
Others | Others |
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo. | |||
T38817 |
Golgicide A-1
GCA-1,Golgicide A-1 |
||
Golgicide A-1 (GCA-1) is a moderately potent cis-diastereomer variant of Golgicide A (GCA) specifically designed to inhibit mosquito reproduction. | |||
T62583 | CBR Agonist-1 | ||
CBR Agonist-1 (27a-cis) 是一种大麻素受体 (CBR) 激动剂,能够作用于 CB1R (Ki: 0.18 μM) 和 CB2R (Ki: 1.22 μM)。CBR Agonist-1 (27a-cis) 能够用于研究内源性大麻素系统相关疾病。 | |||
T73006 |
cis-ccc_R08
|
||
cis-ccc_R08(化合物1)为黄酮衍生物,适用于乙型肝炎病毒(HBV)感染研究,作为cccDNA(共价封闭环状DNA)的抑制剂。 | |||
T75435 |
cis-Vitamin K1
|
||
Cis-Vitamin K1 是一种 Vitamin K 的内源性代谢物。 | |||
T82770 |
CB2R agonist 2
|
Cannabinoid Receptor | GPCR/G Protein |
CB2R agonist 2(compound cis-17-para)为特定CB2R激动剂,具有专一性作用于CB2受体。 | |||
T36077 |
cis-Parinaric Acid
cis-Parinaric Acid,α-Parinaric Acid |
||
cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained wit... | |||
T13064 |
TAB29
|
Others | Others |
TAB29 is a potent peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) inhibitor (IC50 of 874 nM), with therapeutic potential for human cancers. | |||
T124236 |
N-cis-p-Coumaroyltyrosine
|
||
N-cis-p-Coumaroyltyrosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124236,CAS号为 77201-65-1。 | |||
T73778 |
cis-5-Tetradecenoic acid
|
||
cis-5-Tetradecenoic acid,一种存在于血液中的内源性代谢物,主要用于研究长链3羟酰基CoA脱氢酶缺乏症。 | |||
T73851 |
cis-β-Terpineol
|
||
Cis-β-Terpineol为一类单萜类化合物,主要从土库曼假狼紫草地上部分提取。其茎、叶、花均展现抗菌活性。 | |||
T60359 | cis-4-Br-2,5-F2-PCPA | ||
cis-4-Br-2,5-F2-PCPA (S1024) 抑制 LSD1 和 LSD2,Ki 值分别为 94 nM 和 8.4 μM。癌症干细胞中 LSD1异常表达,cis-4-Br-2,5-F2-PCPA 能够通过增加 CCRF-CEM 细胞中二甲基化组蛋白 H3 的 K4 (H3K4) 水平,抑制 LSD1活性和癌细胞增殖。 | |||
T72436 |
cis,trans-Germacrone
|
||
cis,trans-Germacrone 是 Germacrone 的异构体。Germacrone 具有广泛的抗肿瘤、抗氧化和抗炎作用。Germacrone 抑制肺癌细胞增殖并改变 Akt/MDM2/p53。Germacrone 还能在 G1/S 期阻滞细胞周期。 | |||
T74029 |
cis-11-Methyl-2-dodecenoic acid
|
||
cis-11-Methyl-2-dodecenoic acid 是群体感应 (QS) 信号分子,在微生物及真菌的细胞外通讯系统中扮演扩散信号因子(DSF)的角色。它参与调控多种细菌病原体的毒性及生物膜的生成。 | |||
T82508 |
Eciskafusp alfa
|
PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
Eciskafusp alfa是一种针对程序性细胞死亡1(PDCD1,亦称PD-1)的顺式靶向IL2v免疫细胞因子。它优先选择抗原特异性干细胞样PD-1+ TCF-1+ CD8+ T细胞,并促使这些细胞分化成更高效的效应器细胞。Eciskafusp alfa主要用于癌症与慢性感染的研究领域。 | |||
T24692 |
QAQ dichloride
|
||
QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit this effect. This compound is membrane-impermeant and selectively enters pain-sensing neurons expressing endogenous import channels. QAQ dichloride functions as a light-sensitive analgesic and provides a valuable tool for investigating signaling mechanisms involved in acute and ... | |||
T38220 |
11-cis Retinol
|
||
11-cisRetinol is an isomer of vitamin A . It is formed from vitamin A,viaatrans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual cycle.1,211-cisRetinol is an agonist of salamander and human red rod opsins expressed in COS cells and an inverse agonist of salamander red cone opsin, as well as human red and green cone opsins expressed in COS cells.3It promotes pigment formation in cone, but not rod, photorec... | |||
T35817 |
Photoswitchable PAD Inhibitor (technical grade)
|
||
Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without photoactivation, it is a weak inhibitor of PAD2 (IC50 = >100 μM) and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro (kinact/KIs = 2,300, 600, 1,000, and 10,510 M-1min-1 for PAD1-4, respectively) and does not inhibit histone H3 citrullination in HEK29... | |||
T37971 |
12-oxo-13-HOME
|
||
12-oxo-13-HOME is an oxylipin derived from linoleic acid .1It is formedviaa 13-HpODE intermediate that is produced by lipoxygenase-mediated metabolism of linoleic acid.2,3,112-oxo-13-HOME has been found in corn and sunflower seedlings.4 1.Ogorodnikova, A.V., Gorina, S.S., Mukhtarova, L.S., et al.Stereospecific biosynthesis of (9S,13S)-10-oxo-phytoenoic acid in young maize rootsBiochim. Biophys. Acta1851(9)1262-1270(2015) 2.Veldink, G.A., and Vliegenthart, J.F.G.The enzymic conversions of 13-hydr... | |||
T36745 |
cDPCP
|
||
cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting proliferation of MDCK cells expressing the human transporters with IC50values of 8.1 and 1.5 μM, respectively. cDPCP inhibits RNA polymerase II-mediated transcription in a reporter assay using HeLa cells. It increases survival in murine S180 sarcoma and P388 leukemia models when ad... | |||
T37737 |
N-cis-octadec-9Z-enoyl-L-Homoserine lactone
|
||
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gene... | |||
T37738 |
N-cis-tetradec-9Z-enoyl-L-Homoserine lactone
|
||
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gene... | |||
T36376 | SB-612111 | ||
SB-612111 is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model[1]. [1]. Paola F Zaratin, et al. Modification of Nociception and Morphine Tolerance by the Selective Opiate Receptor-Like Orphan Receptor Anta... | |||
T35854 |
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
|
||
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22295 |
cis-3-Hexen-1-ol
叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol |
Others | Others |
cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) 是发现于许多新鲜水果和蔬菜中的一种绿色草味化合物,常用作加工食品的附加风味剂,以提供新鲜的绿色品质,也是多种昆虫的引诱剂。 | |||
TCP2830 |
Neryl acetate
Nerol acetate,Acetic acid neryl ester,(Z)-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯,cis-Geranyl acetate |
Others | Others |
Neryl acetate (Acetic acid neryl ester) 是一种分离自柑桔油中的物质。 | |||
T39821 |
cis-Isolimonenol
(1S,4R)-p-Mentha-2,8-dien-1-ol,cis-Isolimonenol |
||
Cis-Isolimonenol ((1S,4R)-p-Mentha-2,8-dien-1-ol) is a constituent of essential oil. | |||
T83515 |
(Z)-Non-2-en-1-ol
Cis-2-Nonen-1-ol |
||
"(Z)-Non-2-en-1-ol (Cis-2-Nonen-1-ol) 是一种天然产物,主要分布在百香果和仙人掌中,它被广泛用于食品工业以增强食品的风味。" | |||
T40637 |
Gondoic acid
cis-11-Eicosenoicacid,顺-11-二十碳烯酸 |
Others | Others |
Gondoic acid (cis-11-Eicosenoicacid) (cis-11-Eicosenoic acid) 在多种植物油和坚果中可以发现的一种单不饱和长链脂肪酸。[1] | |||
T9512 |
Linoleyl alcohol
CIS,CIS-9,12-OCTADECADIENOL,亚麻醇 |
Others | Others |
Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL) 是一种脂肪醇,是一种没有α-羧基的 Linoleic acid 的结构类似物。 | |||
T4S1962 |
beta-Asarone
β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin |
NF-κB; JNK | MAPK; NF-κB |
beta-Asarone (Cis-Isoelemicin) 是一种石菖蒲中的主要成分,具有免疫抑制、促进安定、中枢神经系统抑制、降温等功能。它可透过血脑屏障,能够预防帕金森病。 | |||
T35749 |
Thymohydroquinone
Thymoquinol |
Antioxidant; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Thymohydroquinone (Thymoquinol) 是中药材百里香、牛至和其他唇形科植物中含有的单萜酚类化合物。 Thymohydroquinone 抑制癌细胞生长、减少氧化应激和调节炎症反应,在无细胞实验中清除2,2-二苯基-1-picrylhydrazyl 自由基(IC50 = 2.4 μg/ml),在浓度为1.6至6.4 μg/ml 的氧自由基吸收能力(ORAC)实验中,它的Trolox 当量值为2.6胸腺对苯二酚对A2780、OVCAR-8和CIS-A2780卵巢癌细胞(IC50分别为3.1、8.9和9.8 μM)和人卵巢永生化上皮细胞(IC50 = 14 μM)的生长有抑制作用,体外对恶性疟原虫也有抑制作用(IC50 = 15.9 μM)。 | |||
TN3666 |
cis-Methylisoeugenol
|
Others | Others |
cis-Methylisoeugenol是一种天然产物,属于天南星科菖蒲属,其产品编号为 TN3666,CAS号为 6380-24-1。cis-Methylisoeugenol可用作对照参考。 | |||
T13617 |
cis-p-Menthan-1,8-diol
4-p-Menthan-1,8-diol |
Others | Others |
cis- p- Menthan- 1, 8- diol is a natural menthane monoterpenoid. | |||
T75679 | 13-cis-Vitamin A palmitate | ||
13-cis-Vitamin A palmitate(13-cis-Retinyl palmitate)是一种在玉米片中发现的维生素A棕榈酸酯的13-顺式异构体。其生物活性相当于全反式维生素A棕榈酸酯(维生素A具生物活性形式)的75%。 | |||
T82718 |
cis-Emodin bianthrone
|
||
Cis-Emodin bianthrone为大黄素蒽酮的高聚氧化产物,其丙酮溶液在空气中表现出稳定性。 | |||
T78486 |
cis-Nerolidol
|
||
cis-Nerolidol,一种倍半萜醇,广泛存在于众多植物中,具抗氧化与抗菌活性,并能增强抗生素效果。 | |||
T80018 |
cis-2-Dodecenoic acid
|
||
cis-2-Dodecenoic acid,最初在Burkholderia cenocepacia中被发现,能够干扰细菌的群体感应系统,从而抑制细菌生物膜的形成和毒力因子的产生。 | |||
T82716 |
cis-Melilotoside
|
||
cis-Melilotoside, 一种 o-Coumaric acid 衍生物,显示出强大的抗氧化活性。该化合物针对T. cruzi表现出适度抗原生动物活性,IC50值为78.2 ug/mL。 | |||
T75603 | cis-Ferulic acid 4-O-β-D-glucopyranoside | ||
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7)是一种从西伯利亚白刺分离的酚糖苷,不仅具有抗氧化活性,还能强效抑制磷酸酶PTP1B。 | |||
TN3255 |
7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone
|
Others | Others |
7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone shows diacylglycerol acyltransferase (DGAT)1 inhibition with IC(50) values of 47.0 microM (for rat liver microsomes) and 160.7 microM (for HepG2 cell microsomes), |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01098 |
ACOD1 Protein, Human, Recombinant (His)
Aconitate decarboxylase 1,IRG1,Cis |
Human | E. coli |
ACOD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.6 kDa and the accession number is A6NK06. | |||
TMPH-01189 |
CISH Protein, Human, Recombinant (GST)
Suppressor of cytokine signaling,Cytokine-inducible SH2-cont... |
Human | E. coli |
CISH Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 55.7 kDa and the accession number is Q9NSE2. | |||
TMPH-02585 |
ACOD1 Protein, Mouse, Recombinant (His & Myc)
Cis-aconitate decarboxylase,Cis-aconitic a... |
Mouse | Baculovirus Insect Cells |
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the anti... | |||
TMPY-02076 |
PIN1 Protein, Human, Recombinant (His)
DOD,peptidylprolyl cis/trans isomerase, NIMA-intera... |
Human | E. coli |
PIN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.3 kDa and the accession number is Q13526-1. | |||
TMPY-02114 |
PIN1 Protein, Human, Recombinant
DOD,UBL5,peptidylprolyl cis/trans isomerase, NIMA-i... |
Human | E. coli |
PIN1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is Q13526-1. | |||
TMPH-03606 |
P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc)
|
Streptomyces | E. coli |
Dioxygenase that catalyzes the 2-oxoglutarate-dependent selective hydroxylation of free L-proline to cis-3-hydroxy-L-proline (cis-3-Hyp). D-proline, trans-4-hydroxy-L-proline, cis-4-hydroxy-L-proline, cis-4-hydroxy-D-proline, and 3,4-dehydro-DL-proline are not substrates. P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.0 kDa and the accession number is P96010. | |||
TMPK-01066 |
BTLA Protein, Human, Recombinant (His & Avi)
BTLA,BTLA1,FLJ16065,CD272,MGC1297... |
Human | HEK293 Cells |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ... | |||
TMPH-02518 |
APOM Protein, Mouse, Recombinant (His)
Ng20,ApoM,Apolipoprotein M,Apo-M |
Mouse | P. pastoris (Yeast) |
Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. APOM Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.3 kDa and the accession number is Q9Z1R3. | |||
TMPJ-00919 |
FKBP2 Protein, Human, Recombinant (His)
also named 13 kDa FK506-binding protein,FK506-bindi... |
Human | HEK293 Cells |
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 an... | |||
TMPY-03413 |
PPIL2 Protein, Human, Recombinant (aa 280-457, His)
UBOX7,Cyp-60,CYP60,CYC4,peptidylprolyl isomerase (cyclophili... |
Human | E. coli |
PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of pro... | |||
TMPK-00530 |
BTLA Protein, Cynomolgus, Recombinant (His)
MGC129743,CD272,BTLA,BTLA1,FLJ160... |
Cynomolgus | HEK293 Cells |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15... | |||
TMPY-03285 |
PPIL1 Protein, Human, Recombinant (His)
CGI-124,PPIase,CYPL1,hCyPX,peptidylprolyl ... |
Human | E. coli |
PPIL1 is a member of the cyclophilin family. Cyclophilins are well conserved and ubiquitous. Members of cyclophilin family take a significant part in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL1 is a peptidylprolyl isomerase(PPIase). It increases the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIL1 is involved in proliferation of cancer cells through modulation of phosphorylation of... | |||
TMPJ-01068 |
FKBP25/FKBP3 Protein, Human, Recombinant (His)
25 kDa FKBP,FKBP-3,Peptidyl-prolyl cis-trans isomer... |
Human | E. coli |
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a... | |||
TMPJ-00710 |
ALDH1A2 Protein, Human, Recombinant (His)
RALDH(II),Retinal dehydrogenase 2,RALDH2,ALDH1A2,Re... |
Human | E. coli |
Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate norma... | |||
TMPY-00140 |
ABP1/AOC1 Protein, Human, Recombinant (His)
amine oxidase, copper containing 1,DAO,ABP1 |
Human | HEK293 Cells |
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co... | |||
TMPY-04137 |
ATP6V1F Protein, Human, Recombinant (GST)
Vma7,ATPase, H+ transporting, lysosomal 14kDa, V |
Human | E. coli |
ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using reverse transcription polymerase chain reaction and touchdown-polymerase chain reaction, respectively. Topology prediction showed that there is one protein kinase C phosphorylation site, two Casein kinase II phosphorylation sites, and one N-myristoylation site in the ATP6V1F protein. U... | |||
TMPY-03603 |
AHSP Protein, Human, Recombinant
ERAF,alpha hemoglobin stabilizing protein,α hemoglobin stabi... |
Human | E. coli |
AHSP, also known as ERAF, is a conserved mammalian erythroid protein which belongs to the AHSP family. It is expressed in blood and bone marrow. AHSP facilitates the production of Hemoglobin A by stabilizing free α-globin. It rapidly binds to ferrous α with association (k'(AHSP)) and dissociation (k(AHSP)) rate constants of ≈1 μm(-1) s(-1) and .2 s(-1), respectively, at pH 7.4 at 22 ℃. A small slow phase was observed when AHSP binds to excess ferrous αCO. This slow phase appears to be due to cis... | |||
TMPJ-01212 |
ULBP-1 Protein, Mouse, Recombinant (His)
RAET1I,ULBP1,NKG2DL1 |
Mouse | HEK293 Cells |
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or inte... | |||
TMPY-04451 |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1) |
Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone... |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03745 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02030 |
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T... |
Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... | |||
TMPY-01894 |
SIGIRR Protein, Human, Recombinant (His)
TIR8,single immunoglobulin and toll-interleukin 1 r... |
Human | HEK293 Cells |
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1. | |||
TMPY-01247 |
FLT3 Protein, Human, Recombinant (T227M, His)
FLK2,FLK-2,CD135,STK1,fms-related tyrosine... |
Human | HEK293 Cells |
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1. | |||
TMPY-02779 |
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
thyroid peroxidase,MSA,TPX,TDH2A |
Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i... | |||
TMPY-03290 |
HGF Protein, Mouse, Recombinant
hepatocyte growth factor (hepapoietin A,NK1,scatter... |
Mouse | HEK293 Cells |
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1. | |||
TMPY-04970 |
TIGIT Protein, Human, Recombinant (hFc)
WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom... |
Human | HEK293 Cells |
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1. | |||
TMPY-01147 |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
RSPO,CRISTIN3,R-spondin 1 |
Human | HEK293 Cells |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1. | |||
TMPY-04346 |
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPY-00947 |
VCAM-1 Protein, Human, Recombinant (hFc)
INCAM-100,CD106,VCAM-1,vascular c... |
Human | HEK293 Cells |
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1. | |||
TMPY-01949 |
CD19 Protein, Human, Recombinant (His)
CD19 molecule,B4,CVID3 |
Human | HEK293 Cells |
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1. | |||
TMPY-04165 |
FGFR3 Protein, Human, Recombinant (His)
JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1. | |||
TMPY-00820 |
IgG1 Fc Protein, Human, Recombinant (C103S)
Ighg1,IgG1 Fc |
Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1. | |||
TMPY-01146 |
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
HHF5,CD220,insulin receptor |
Human | HEK293 Cells |
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. | |||
TMPY-04348 |
CTLA-4 Protein, Human, Recombinant (His)
ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ... |
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1. | |||
TMPY-02813 |
ErbB4 Protein, Human, Rhesus, Recombinant (His)
erb-b2 receptor tyrosine kinase 4 |
Human,Rhesus | HEK293 Cells |
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1. | |||
TMPY-05220 |
TSLP Protein, Human, Recombinant (R127A & R130S, His)
thymic stromal lymphopoietin |
Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. | |||
TMPY-01827 |
CD30/TNFRSF8 Protein, Human, Recombinant (His)
D1S166E,tumor necrosis factor receptor sup... |
Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. | |||
TMPY-00853 |
IL-1RA Protein, Human, Recombinant
DIRA,IL1RA,interleukin 1 receptor antagoni... |
Human | E. coli |
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1. | |||
TMPY-01850 |
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC11987... |
Human | HEK293 Cells |
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... | |||
TMPY-02245 |
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ |
Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... | |||
TMPY-00203 |
LOXL2 Protein, Mouse, Recombinant (His)
1110004B06Rik,4930526G1<... |
Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act... | |||
TMPY-01851 |
CD73 Protein, Human, Recombinant (His)
eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD... |
Human | HEK293 Cells |
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1. | |||
TMPY-01281 |
ACVR2B Protein, Mouse, Recombinant (His)
ActRIIB,activin A receptor, type IIB,4930516B21... |
Mouse | HEK293 Cells |
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1. | |||
TMPY-03967 |
BTN3A3 Protein, Human, Recombinant (His)
BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3 |
Human | HEK293 Cells |
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1. | |||
TMPY-02525 |
RGMA Protein, Human, Recombinant (His)
repulsive guidance molecule family member a,RGM |
Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form... | |||
TMPY-05208 |
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL<... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-00978 |
Progranulin Protein, Human, Recombinant (His)
PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli... |
Human | HEK293 Cells |
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1. | |||
TMPY-03407 |
NQO1 Protein, Human, Recombinant (His)
NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1... |
Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex... | |||
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