36
1
138
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3189 |
B7/CD28 interaction inhibitor 1
CTLA-4 inhibitor |
Others | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) 是B7.1-CD28相互作用抑制剂(IC50:50 nM)。 | |||
T78292 |
Ifinatamab
Anti-Human B7-H3 |
||
Ifinatamab为一抗人B7同源3蛋白(HumanB7-H3)的单克隆免疫球蛋白G1-kappa,属于糖型α免疫调节剂类。 | |||
T83846 |
HOXB7 (8-25) TFA
Homeobox B7 (8-25) |
||
HOXB7 (8-25) 是 homeobox B7 (HOXB7) 的肽段,是细胞增殖的主要调控因子和肿瘤基因途径的激活剂。通过 HOXB7 (8-25) 肽脉冲的树突状细胞展示抗原,这些树突状细胞来源于分离的人类外周血单核细胞(PBMCs),刺激CD4+辅助T细胞的激活和IFN-γ的产生,从而引发特异性和多向性肿瘤反应性的抗肿瘤反应。 | |||
T69567L |
UCB7362 hydrochloride
UCB7362 hydrochloride(2610631-17-7 Free base),UCB7362 HCl |
Parasite | Microbiology/Virology |
UCB7362 hydrochloride (UCB7362 HCl)是一种可口服高效性 plasmepsin X (PMX) 抑制剂(IC50: 7 nM),具有抗疟活性,可抑制寄生虫 (parasite) 生长。 | |||
T69567 |
UCB7362
GLXC-26743 |
Parasite | Microbiology/Virology |
UCB7362 (GLXC-26743) 是一种可口服且具有有效性的 plasmepsin X (PMX) 抑制剂,具有抗疟疾活性。UCB7362 可抑制寄生虫 (parasite) 繁殖。 | |||
T1808 |
kb-NB77-78
|
Serine/threonin kinase | Cell Cycle/Checkpoint; Metabolism |
kb-NB77-78 是一种 CID797718 的类似物,但不影响 PKD。它是母体化合物 CID755673(PKD1 抑制剂)的合成副产物。 | |||
T4352 |
SB756050
SB-756050,SB 756050 |
GPCR19 | GPCR/G Protein |
SB756050 是TGR5选择性激动剂。它用于二型糖尿病研究的潜力。 | |||
T64372 |
DB722
|
Others | Others |
DB722是一种具有DNA 结合活性的呋喃脒类似物。DB722显示抗增殖活性。 | |||
T75946 |
Lei-Dab7 TFA
|
||
Lei-Dab7 TFA, a selective and high-affinity blocker of the K Ca 2.2 (SK2) channel with a dissociation constant (K d) of 3.8 nM, demonstrates over 200-fold selectivity for K Ca 2.2 compared to K Ca 2.1, K Ca 2.3, K Ca 3.1, K v, and Kir2.1. Furthermore, Lei-Dab7 TFA enhances theta-burst responses and long-term potentiation (LTP) in rat hippocampal slices in vitro. | |||
T9661 |
MB710
|
||
MB710 是一种氨基苯并噻唑衍生物,是致癌 p53 突变体 Y220C 的稳定剂。MB710 与 Y220C 口袋紧密结合并稳定p53-Y220C,Kd 值为 4 μM。 MB710 在 p53-Y220C 细胞系中显示抗癌活性。 | |||
T63412 | DB772 hydrate | ||
DB772 hydrate 是一种牛病毒性腹泻病毒 (BVDV) 抑制剂,同时表现出抗朊病毒作用。 | |||
T33219 |
MB725
MB 725,MB-725 |
||
MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation. | |||
T23966 |
DB772
DB 772,DB-772 |
||
DB772 is a scrapie prion accumulation inhibitor. | |||
T26194 |
SKLB70326
SKLB 70326,SKLB-70326 |
||
SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells. | |||
T37374 |
URB754
|
||
URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. There is evidence that the MAGL inhibitory activity of URB754 may be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial preparations. URB754 inhibits rat brain fa... | |||
T26960 |
CB7833407
|
||
CB7833407 is a selective Adenylyl Cyclase isoform-2 (AC2) inhibitor. | |||
T82179 |
HOXB7 8–25
MDM2 32-46 |
||
HOXB7 8–25 (MDM2 32-46)为来源于MDM2的肽段,能够特异性诱导抗原和激活肿瘤反应性的CD4+ T细胞。 | |||
TP2007 |
Lei-Dab7
Lei-Dab 7 |
||
High affinity, selective KCa2.2 (SK2) channel blocker (Kd = 3.8 nM). Exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, IK, Kv and Kir2.1. Increases theta-burst responses and increases LTP in rat hippocampal slices in vitro. Convulsive | |||
T78266 |
Anti-Mouse LAG-3 Antibody (C9B7W)
|
||
Anti-MouseLAG-3Antibody为针对小鼠LAG-3的Rat源IgG1抗体抑制剂。 | |||
T78274 |
Omburtamab
|
||
Omburtamab是一款针对CD276(亦称为B7-H3)的单克隆抗体,后者为在人类实体肿瘤中表达的B7/CD28免疫球蛋白家族成员。此抗体能够结合肿瘤组织,被应用于多种癌症的研究中。 | |||
T9901A-002 |
Enoblituzumab
MGA271,TJ-271 |
Others | Others |
Enoblituzumab 是一种人源化 IgG1κ 单克隆抗体,可以识别人 B7-H3 蛋白 ,可用于研究非小细胞肺癌 (NSCLC)等实体肿瘤。 | |||
T77909 |
Mirzotamab
|
||
Mirzotamab clezutoclax(ABBV-155)是一种IgG1κ型靶向CD276/B7-H3的抗体偶联物(ADC),通过与BCL抑制剂Clezutoclax结合而构成。该化合物用于参与针对复发/难治性实体瘤的紫杉烷相关研究。 | |||
TP1822L |
CEF6 acetate(913545-15-0 free base)
|
Influenza Virus | Microbiology/Virology |
CEF6 acetate(913545-15-0 free base) 是 HLA-B7限制性流感病毒核蛋白表位,属于 CEF 对照肽。 CEF 对照肽长度为 8-12 个氨基酸,其序列来自人类巨细胞病毒、爱泼斯坦-巴尔病毒和流感病毒。 | |||
T7206L |
2-Iminobiotin hydrobromide
2-亚氨基生物素,Guanidinobiotin,2-亚氨基生物素盐酸盐 |
NOS; NO Synthase | Immunology/Inflammation |
2-Iminobiotin hydrobromide (Guanidinobiotin) 是生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,可作用于小鼠 iNOS(Ki:21.8 μM)和大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。 | |||
T77104 | Obrindatamab | ||
Obrindatamab 是一种人源化抗 B7-H3/CD3双特异性抗体。Obrindatamab 结合 B7-H3和 CD3,从而介导针对表达 B7-H3的癌细胞的重定向细胞毒性 T 淋巴细胞 (CTL) 活性。Obrindatamab 可用于癌症研究。 | |||
T78287 |
Alsevalimab
|
||
Alsevalimab为针对B7-H4的人源化单克隆抗体。 | |||
T81345 |
Puxitatug
|
||
Puxitatug是一种针对[Homo sapiens VTCN1 (包含T细胞激活抑制剂1、B7家族成员H4、B7H4、B7-H4的Vset结构域)]的Homo sapiens免疫球蛋白G1-κ型单克隆抗体。 | |||
T82613 |
Danburstotug
STI-3031,IMC-001 |
PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
Danburstotug (IMC-001) 是一种对CD274(程序性细胞死亡 1 配体1、PDL1、B7 同源物 1、B7-H1)具有亲和力的IgG1-lambda人源化单克隆抗体。该抗体不仅能够促进免疫应答,还显示出对抗肿瘤的潜力。 | |||
T77905 |
Vobramitamab
AEX-4089 |
||
Vobramitamab为针对人源B7-H3的单克隆抗体(mAb)。该抗体通过一个可切割的连接物与前药seco-DUBA相结合,构成一种抗体-药物偶联物(ADC)名为MGC018。 | |||
T74735 |
Gly-Cyclopropane-Exatecan
|
||
Gly-Cyclopropane-Exatecan (compound 5c) 参与合成抗 B7-H4抗体活性分子缀合物 (ADC),含有 DNA 拓扑异构酶 I (TopoisomeraseI) 抑制剂 Exatecan 。Gly-Cyclopropane-Exatecan 参与形成的 ADC 为 hu2F7-Exatecan (compound 34) 具有体内外抗肿瘤活性。 | |||
TP1822 |
CEF6
|
||
CEF6, a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in length, with sequences derived from the human cytomegalovirus, Epstein-Barr virus and influenza virus. | |||
T75292 |
Biotin sodium
|
||
Biotin (Vitamin B7) sodium 是一种水溶性维生素 B,是人体五种羧化酶的辅酶,参与脂肪酸、异亮氨酸和缬氨酸的合成,并参与糖异生。Biotin sodium 是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢的必需物质。 | |||
T78107 |
Reltecimod TFA
AB-103 TFA |
||
Reltecimod (AB-103) TFA 是一款针对 T 细胞特异性表面糖蛋白CD28(TP44) 的拮抗剂。该化合物能够有效抵御各类细菌感染、细菌产生的外毒素和内毒素,以及电离辐射。其通过特异性目标定位并调节 CD28/B7-2 共刺激通路以减弱炎症反应,但并不完全抑制该通路。Reltecimod TFA 主要用于坏死性软组织感染(NSTIs)的研究。 | |||
T36136 |
Biotin (R)-Sulfoxide
|
||
Biotin (R)-sulfoxide is a metabolite of the coenzyme biotin .1 1.Carling, R.S., and Turner, C.Methods for assessment of biotin (Vitamin B7)Laboratory assessment of vitamin status193-217(2019) | |||
T36137 |
Biotin (S)-sulfoxide
|
||
Biotin (S)-sulfoxide is an inactive metabolite of the coenzyme biotin .1,2It has also been found inE. coliand is reduced by the biotin sulfoxide reduction system as a source of biotin.3 1.Denkel, L.A., Rhen, M., and Bange, F.-C.Biotin sulfoxide reductase contributes to oxidative stress tolerance and virulence in Salmonella enterica serovar TyphimuriumMicrobiology (Reading)159(Pt 7)1447-1458(2013) 2.Carling, R.S., and Turner, C.Methods for assessment of biotin (Vitamin B7)Laboratory assessment of... | |||
T7206 |
2-Iminobiotin
2-IMINOBIOTIN HYDROBROMIDE,2-亚氨基生物素,Guanidinobiotin |
NOS; NO Synthase | Immunology/Inflammation |
2-Iminobiotin (Guanidinobiotin) 是一种生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,能够作用于小鼠 iNOS(Ki:21.8 μM)及大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1116 |
Biotin
Vitamin B7,生物素,D-Biotin,Vitamin H,D-生物素(维生素H) |
||
Biotin (Vitamin H) 是一种水溶性B族维生素,是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢所必需的。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02031 |
B7-H3 Protein, Human, Recombinant (His)
CD276 molecule,B7-H3,4Ig-B7-H3,B7... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-00674 |
B7-1 Protein, Human, Recombinant
CD28LG1,B7,CD80 molecule,LAB7,B7.... |
Human | HEK293 Cells |
B7-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is A0N0P2. | |||
TMPY-04262 |
B7-H3 Protein, Human, Recombinant (His), Biotinylated
B7H3,4Ig-B7-H3,CD276 molecule,B7R... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-05641 |
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
4Ig-B7-H3,B7-H3,B7H3,CD276 molecu... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 49.8 kDa and the accession number is Q5ZPR3. | |||
TMPY-03524 |
B7-H4 Protein, Human, Recombinant (His)
PRO1291,B7X,B7H4,B7-H4,VCTN1,... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-05208 |
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL1,PDCD1LG1,B7H1, |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-04949 |
PD-L1 Protein, Human, Recombinant (His), Biotinylated
PDCD1LG1,B7H1,PD-L1,B7-H1,B7-H,CD... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-04343 |
PD-L1 Protein, Human, Recombinant (His)
PDL1,B7-H,B7H1,PDCD1LG1,CD274 molecule,PD-... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1. | |||
TMPK-00314 |
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
B7-H3,PSEC0249,PRO352, 4Ig-B7-H3,B7 |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m... | |||
TMPK-01263 |
B7-H7 Protein, Cynomolgus, Recombinant (His)
B7H7,B7-H7,HHLA2,B7 Homolog 7 |
Cynomolgus | HEK293 Cells |
B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. | |||
TMPK-00315 |
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated
4Ig-B7-H3,CD276,UNQ309,B7-H3,PRO352,PSEC0... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T... | |||
TMPY-00643 |
B7-H3 Protein, Human, Recombinant (hFc)
B7RP-2,B7H3,B7-H3,4Ig-B7... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.3 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-05279 |
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated
B7RP-2,B7-H3,CD276 molecule,B7H3,... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-01063 |
B7-1 Protein, Human, Recombinant (His)
BB1,CD28LG1,B7-1,CD28LG,B7,B7.1,L... |
Human | HEK293 Cells |
B7-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0N0P2. | |||
TMPJ-00630 |
B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7,CD80,T-lymphocyte activation antigen CD80,Activa... |
Cynomolgus | HEK293 Cells |
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ... | |||
TMPY-06298 |
B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated
CD28LG1,B7-1,B7.1,BB1,CD28LG,CD80 molecule... |
Human | HEK293 Cells |
B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.12 kDa and the accession number is A0N0P2. | |||
TMPY-01180 |
CD86 Protein, Human, Recombinant (His)
CD86 antigen,B70,B7.2,B7-2,CD28LG... |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3. | |||
TMPK-00280 |
B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated
NCR3LG1,B7H6,DKFZp686O24166,B7-H6,DKFZp686... |
Human | HEK293 Cells |
B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. | |||
TMPY-05379 |
B7-1 Protein, Human, Recombinant (hFc)
B7-1,B7.1,LAB7,CD28LG,CD80 molecu... |
Human | HEK293 Cells |
B7-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is A0N0P2. | |||
TMPY-05016 |
HHLA2 Protein, Human, Recombinant (His)
HERV-H LTR-associating 2,HHLA2,B7-H7,B7H7 |
Human | HEK293 Cells |
HHLA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9UM44-1. | |||
TMPJ-00958 |
B7-1 Protein, Rabbit, Recombinant (His)
Activation B7-1 antigen,T-lymphocyte activation ant... |
Rabbit | HEK293 Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ... | |||
TMPY-06581 |
B7-H3 Protein, Human, Recombinant (isoform 2, His)
CD276 molecule,B7H3,B7RP-2,4Ig-B7... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (isoform 2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.52 kDa and the accession number is Q5ZPR3-2. | |||
TMPK-01017 |
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
B7H3,B7-H3,B7 homolog 3,PSEC0249,... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weig... | |||
TMPK-01016 |
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
B7H3, UNQ309,PRO352,PSEC0249,B7 homolog 3,... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular w... | |||
TMPK-01018 |
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
PRO352,B7H3, UNQ309,PSEC0249,CD276,B7-H3,<... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weig... | |||
TMPK-00178 |
B7-1 Protein, Human, Recombinant (His & Avi)
B71,CD80,BB1,LAB7,B7-1,B7 |
Human | HEK293 Cells |
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. B7-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is P33681-1. | |||
TMPK-00882 |
B7-2 Protein, Human, Recombinant (hFc)
B7-2,FUN-1,B7-2 antigen,CD86,LAB7... |
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.... | |||
TMPY-04619 |
B7-H6 Protein, Human, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand 1,DKFZp68... |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85. | |||
TMPK-00653 |
B7-2 Protein, Cynomolgus, Recombinant (His)
B72,MGC34413,LAB72,B7-2,FUN-1, |
Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His... | |||
TMPK-00880 |
B7-2 Protein, Human, Recombinant (His & Avi)
B70,B7-2 antigen,B7-2,CD86 molecu... |
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPJ-00959 |
B7-2 Protein, Rabbit, Recombinant (His)
CD86,T-lymphocyte activation antigen CD86,Activation B7<... |
Rabbit | HEK293 Cells |
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071. | |||
TMPY-00377 |
B7-H6 Protein, Human, Recombinant (hFc)
DKFZp686O24166,B7H6,B7-H6,natural killer c... |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.4 kDa and the accession number is Q68D85. | |||
TMPK-00881 |
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
LAB72,B7-2,B7-2 antigen,FUN-1,CD8... |
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPY-06178 |
B7-H6 Protein, Human, Recombinant (His), Biotinylated
natural killer cell cytotoxicity receptor 3 ligand 1,B7<... |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85. | |||
TMPK-00179 |
B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated
B7.1,CD80,B7,CD80 molecule,CD28LG1,B7<... |
Human | HEK293 Cells |
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is P33681-1. | |||
TMPK-00172 |
B7-H4 Protein, Human, Recombinant (His & Avi)
B7H4,B7x,VTCN1,PRO1291,B7S1,B... |
Human | HEK293 Cells |
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status . | |||
TMPJ-00632 |
B7-2 Protein, Cynomolgus, Recombinant (hFc)
T-lymphocyte activation antigen CD86 isoform 1,Activation |
Cynomolgus | HEK293 Cells |
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4. | |||
TMPJ-00641 |
B7-2 Protein, Rhesus macaque, Recombinant (His)
Activation B7-2 antigen,T-lymphocyte activation ant... |
Rhesus | HEK293 Cells |
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8. | |||
TMPK-00192 |
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)
B7RP1B7-like protein Gl50,B7-H2 |
Human | HEK293 Cells |
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01264 |
B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)
B7H2,CD275,B7-H2,B7RP1B7... |
Cynomolgus | HEK293 Cells |
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His... | |||
TMPY-05280 |
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated
B7S1,B7X,VCTN1,B7h.5,V-set domain... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-04957 |
PD-L2 Protein, Human, Recombinant (His), Biotinylated
B7DC,Btdc,B7-DC,bA574F11.2,PDL2,programmed... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPJ-00175 |
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
V-set domain containing T cell activation inhibitor 1,B7... |
Rhesus | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the s... | |||
TMPK-00193 |
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated
B7H2,B7RP-1,ICOS ligand,GL50,B7-H... |
Human | HEK293 Cells |
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPY-05080 |
B7-H4 Protein, Human, Recombinant (mFc)
B7H4,VCTN1,V-set domain containing T cell activatio... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-03009 |
B7-H4 Protein, Human, Recombinant (hFc)
B7h.5,B7X,PRO1291,B7S1,B7 |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-04346 |
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,p... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPY-03219 |
VISTA Protein, Human, Recombinant (His)
DD1α,V-set immunoregulatory receptor,SISP1,DD1alpha,B7 |
Human | HEK293 Cells |
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1. | |||
TMPY-05322 |
B7-H4 Protein, Mouse, Recombinant (His)
BC032925,B7h4,B7x,V-set domain containing ... |
Mouse | HEK293 Cells |
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5. | |||
TMPK-01186 |
B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)
VSIR,B7H5,4632428N05Rik,SISP1,PP2135,Dies1,PD-1H,VI... |
Human | HEK293 Cells |
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-H5/Gi24/VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 19 kDa and the accession number is Q9H7M9. | |||
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