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Search Results for " b7 "
Targets Recommended: Others

36

抑制剂 & 化合物

1

天然产物

138

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T3189 B7/CD28 interaction inhibitor 1

CTLA-4 inhibitor

Others Others
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) 是B7.1-CD28相互作用抑制剂(IC50:50 nM)。
T78292 Ifinatamab

Anti-Human B7-H3

Ifinatamab为一抗人B7同源3蛋白(HumanB7-H3)的单克隆免疫球蛋白G1-kappa,属于糖型α免疫调节剂类。
T83846 HOXB7 (8-25) TFA

Homeobox B7 (8-25)

HOXB7 (8-25) 是 homeobox B7 (HOXB7) 的肽段,是细胞增殖的主要调控因子和肿瘤基因途径的激活剂。通过 HOXB7 (8-25) 肽脉冲的树突状细胞展示抗原,这些树突状细胞来源于分离的人类外周血单核细胞(PBMCs),刺激CD4+辅助T细胞的激活和IFN-γ的产生,从而引发特异性和多向性肿瘤反应性的抗肿瘤反应。
T69567L UCB7362 hydrochloride

UCB7362 hydrochloride(2610631-17-7 Free base),UCB7362 HCl

Parasite Microbiology/Virology
UCB7362 hydrochloride (UCB7362 HCl)是一种可口服高效性 plasmepsin X (PMX) 抑制剂(IC50: 7 nM),具有抗疟活性,可抑制寄生虫 (parasite) 生长。
T69567 UCB7362

GLXC-26743

Parasite Microbiology/Virology
UCB7362 (GLXC-26743) 是一种可口服且具有有效性的 plasmepsin X (PMX) 抑制剂,具有抗疟疾活性。UCB7362 可抑制寄生虫 (parasite) 繁殖。
T1808 kb-NB77-78

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
kb-NB77-78 是一种 CID797718 的类似物,但不影响 PKD。它是母体化合物 CID755673(PKD1 抑制剂)的合成副产物。
T4352 SB756050

SB-756050,SB 756050

GPCR19 GPCR/G Protein
SB756050 是TGR5选择性激动剂。它用于二型糖尿病研究的潜力。
T64372 DB722

Others Others
DB722是一种具有DNA 结合活性的呋喃脒类似物。DB722显示抗增殖活性。
T75946 Lei-Dab7 TFA

Lei-Dab7 TFA, a selective and high-affinity blocker of the K Ca 2.2 (SK2) channel with a dissociation constant (K d) of 3.8 nM, demonstrates over 200-fold selectivity for K Ca 2.2 compared to K Ca 2.1, K Ca 2.3, K Ca 3.1, K v, and Kir2.1. Furthermore, Lei-Dab7 TFA enhances theta-burst responses and long-term potentiation (LTP) in rat hippocampal slices in vitro.
T9661 MB710

MB710 是一种氨基苯并噻唑衍生物,是致癌 p53 突变体 Y220C 的稳定剂。MB710 与 Y220C 口袋紧密结合并稳定p53-Y220C,Kd 值为 4 μM。 MB710 在 p53-Y220C 细胞系中显示抗癌活性。
T63412 DB772 hydrate

DB772 hydrate 是一种牛病毒性腹泻病毒 (BVDV) 抑制剂,同时表现出抗朊病毒作用。
T33219 MB725

MB 725,MB-725

MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.
T23966 DB772

DB 772,DB-772

DB772 is a scrapie prion accumulation inhibitor.
T26194 SKLB70326

SKLB 70326,SKLB-70326

SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.
T37374 URB754

URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. There is evidence that the MAGL inhibitory activity of URB754 may be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial preparations. URB754 inhibits rat brain fa...
T26960 CB7833407

CB7833407 is a selective Adenylyl Cyclase isoform-2 (AC2) inhibitor.
T82179 HOXB7 8–25

MDM2 32-46

HOXB7 8–25 (MDM2 32-46)为来源于MDM2的肽段,能够特异性诱导抗原和激活肿瘤反应性的CD4+ T细胞。
TP2007 Lei-Dab7

Lei-Dab 7

High affinity, selective KCa2.2 (SK2) channel blocker (Kd = 3.8 nM). Exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, IK, Kv and Kir2.1. Increases theta-burst responses and increases LTP in rat hippocampal slices in vitro. Convulsive
T78266 Anti-Mouse LAG-3 Antibody (C9B7W)

Anti-MouseLAG-3Antibody为针对小鼠LAG-3的Rat源IgG1抗体抑制剂。
T78274 Omburtamab

Omburtamab是一款针对CD276(亦称为B7-H3)的单克隆抗体,后者为在人类实体肿瘤中表达的B7/CD28免疫球蛋白家族成员。此抗体能够结合肿瘤组织,被应用于多种癌症的研究中。
T9901A-002 Enoblituzumab

MGA271,TJ-271

Others Others
Enoblituzumab 是一种人源化 IgG1κ 单克隆抗体,可以识别人 B7-H3 蛋白 ,可用于研究非小细胞肺癌 (NSCLC)等实体肿瘤。
T77909 Mirzotamab

Mirzotamab clezutoclax(ABBV-155)是一种IgG1κ型靶向CD276/B7-H3的抗体偶联物(ADC),通过与BCL抑制剂Clezutoclax结合而构成。该化合物用于参与针对复发/难治性实体瘤的紫杉烷相关研究。
TP1822L CEF6 acetate(913545-15-0 free base)

Influenza Virus Microbiology/Virology
CEF6 acetate(913545-15-0 free base) 是 HLA-B7限制性流感病毒核蛋白表位,属于 CEF 对照肽。 CEF 对照肽长度为 8-12 个氨基酸,其序列来自人类巨细胞病毒、爱泼斯坦-巴尔病毒和流感病毒。
T7206L 2-Iminobiotin hydrobromide

2-亚氨基生物素,Guanidinobiotin,2-亚氨基生物素盐酸盐

NOS; NO Synthase Immunology/Inflammation
2-Iminobiotin hydrobromide (Guanidinobiotin) 是生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,可作用于小鼠 iNOS(Ki:21.8 μM)和大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。
T77104 Obrindatamab

Obrindatamab 是一种人源化抗 B7-H3/CD3双特异性抗体。Obrindatamab 结合 B7-H3和 CD3,从而介导针对表达 B7-H3的癌细胞的重定向细胞毒性 T 淋巴细胞 (CTL) 活性。Obrindatamab 可用于癌症研究。
T78287 Alsevalimab

Alsevalimab为针对B7-H4的人源化单克隆抗体。
T81345 Puxitatug

Puxitatug是一种针对[Homo sapiens VTCN1 (包含T细胞激活抑制剂1、B7家族成员H4、B7H4、B7-H4的Vset结构域)]的Homo sapiens免疫球蛋白G1-κ型单克隆抗体。
T82613 Danburstotug

STI-3031,IMC-001

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
Danburstotug (IMC-001) 是一种对CD274(程序性细胞死亡 1 配体1、PDL1、B7 同源物 1、B7-H1)具有亲和力的IgG1-lambda人源化单克隆抗体。该抗体不仅能够促进免疫应答,还显示出对抗肿瘤的潜力。
T77905 Vobramitamab

AEX-4089

Vobramitamab为针对人源B7-H3的单克隆抗体(mAb)。该抗体通过一个可切割的连接物与前药seco-DUBA相结合,构成一种抗体-药物偶联物(ADC)名为MGC018。
T74735 Gly-Cyclopropane-Exatecan

Gly-Cyclopropane-Exatecan (compound 5c) 参与合成抗 B7-H4抗体活性分子缀合物 (ADC),含有 DNA 拓扑异构酶 I (TopoisomeraseI) 抑制剂 Exatecan 。Gly-Cyclopropane-Exatecan 参与形成的 ADC 为 hu2F7-Exatecan (compound 34) 具有体内外抗肿瘤活性。
TP1822 CEF6

CEF6, a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in length, with sequences derived from the human cytomegalovirus, Epstein-Barr virus and influenza virus.
T75292 Biotin sodium

Biotin (Vitamin B7) sodium 是一种水溶性维生素 B,是人体五种羧化酶的辅酶,参与脂肪酸、异亮氨酸和缬氨酸的合成,并参与糖异生。Biotin sodium 是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢的必需物质。
T78107 Reltecimod TFA

AB-103 TFA

Reltecimod (AB-103) TFA 是一款针对 T 细胞特异性表面糖蛋白CD28(TP44) 的拮抗剂。该化合物能够有效抵御各类细菌感染、细菌产生的外毒素和内毒素,以及电离辐射。其通过特异性目标定位并调节 CD28/B7-2 共刺激通路以减弱炎症反应,但并不完全抑制该通路。Reltecimod TFA 主要用于坏死性软组织感染(NSTIs)的研究。
T36136 Biotin (R)-Sulfoxide

Biotin (R)-sulfoxide is a metabolite of the coenzyme biotin .1 1.Carling, R.S., and Turner, C.Methods for assessment of biotin (Vitamin B7)Laboratory assessment of vitamin status193-217(2019)
T36137 Biotin (S)-sulfoxide

Biotin (S)-sulfoxide is an inactive metabolite of the coenzyme biotin .1,2It has also been found inE. coliand is reduced by the biotin sulfoxide reduction system as a source of biotin.3 1.Denkel, L.A., Rhen, M., and Bange, F.-C.Biotin sulfoxide reductase contributes to oxidative stress tolerance and virulence in Salmonella enterica serovar TyphimuriumMicrobiology (Reading)159(Pt 7)1447-1458(2013) 2.Carling, R.S., and Turner, C.Methods for assessment of biotin (Vitamin B7)Laboratory assessment of...
T7206 2-Iminobiotin

2-IMINOBIOTIN HYDROBROMIDE,2-亚氨基生物素,Guanidinobiotin

NOS; NO Synthase Immunology/Inflammation
2-Iminobiotin (Guanidinobiotin) 是一种生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,能够作用于小鼠 iNOS(Ki:21.8 μM)及大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。

化合物

B7/CD28 interaction inhibitor 1
Cat.No: T3189
Synonym: CTLA-4 inhibitor
Target: Others
Ifinatamab
Cat.No: T78292
Synonym: Anti-Human B7-H3
Target:
HOXB7 (8-25) TFA
Cat.No: T83846
Synonym: Homeobox B7 (8-25)
Target:
UCB7362 hydrochloride
Cat.No: T69567L
Synonym: UCB7362 hydrochloride(2610631-17-7 Free base),UCB7362 HCl
Target: Parasite
UCB7362
Cat.No: T69567
Synonym: GLXC-26743
Target: Parasite
kb-NB77-78
Cat.No: T1808
Synonym:
Target: Serine/threonin kinase
SB756050
Cat.No: T4352
Synonym: SB-756050,SB 756050
Target: GPCR19
DB722
Cat.No: T64372
Synonym:
Target: Others
Lei-Dab7 TFA
Cat.No: T75946
Synonym:
Target:
MB710
Cat.No: T9661
Synonym:
Target:
DB772 hydrate
Cat.No: T63412
Synonym:
Target:
MB725
Cat.No: T33219
Synonym: MB 725,MB-725
Target:
DB772
Cat.No: T23966
Synonym: DB 772,DB-772
Target:
SKLB70326
Cat.No: T26194
Synonym: SKLB 70326,SKLB-70326
Target:
URB754
Cat.No: T37374
Synonym:
Target:
CB7833407
Cat.No: T26960
Synonym:
Target:
HOXB7 8–25
Cat.No: T82179
Synonym: MDM2 32-46
Target:
Lei-Dab7
Cat.No: TP2007
Synonym: Lei-Dab 7
Target:
Anti-Mouse LAG-3 Antibody (C9B7W)
Cat.No: T78266
Synonym:
Target:
Omburtamab
Cat.No: T78274
Synonym:
Target:
Enoblituzumab
Cat.No: T9901A-002
Synonym: MGA271,TJ-271
Target: Others
Mirzotamab
Cat.No: T77909
Synonym:
Target:
CEF6 acetate(913545-15-0 free base)
Cat.No: TP1822L
Synonym:
Target: Influenza Virus
2-Iminobiotin hydrobromide
Cat.No: T7206L
Synonym: 2-亚氨基生物素,Guanidinobiotin,2-亚氨基生物素盐酸盐
Target: NOS, NO Synthase
Obrindatamab
Cat.No: T77104
Synonym:
Target:
Alsevalimab
Cat.No: T78287
Synonym:
Target:
Puxitatug
Cat.No: T81345
Synonym:
Target:
Danburstotug
Cat.No: T82613
Synonym: STI-3031,IMC-001
Target: PD-1/PD-L1
Vobramitamab
Cat.No: T77905
Synonym: AEX-4089
Target:
Gly-Cyclopropane-Exatecan
Cat.No: T74735
Synonym:
Target:
CEF6
Cat.No: TP1822
Synonym:
Target:
Biotin sodium
Cat.No: T75292
Synonym:
Target:
Reltecimod TFA
Cat.No: T78107
Synonym: AB-103 TFA
Target:
Biotin (R)-Sulfoxide
Cat.No: T36136
Synonym:
Target:
Biotin (S)-sulfoxide
Cat.No: T36137
Synonym:
Target:
2-Iminobiotin
Cat.No: T7206
Synonym: 2-IMINOBIOTIN HYDROBROMIDE,2-亚氨基生物素,Guanidinobiotin
Target: NOS, NO Synthase
Cat. No. Product Name Target Signaling Pathways
T1116 Biotin

Vitamin B7,生物素,D-Biotin,Vitamin H,D-生物素(维生素H)

Biotin (Vitamin H) 是一种水溶性B族维生素,是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢所必需的。

天然产物

Biotin
Cat.No: T1116
Synonym: Vitamin B7,生物素,D-Biotin,Vitamin H,D-生物素(维生素H)
Target:
Cat. No. Product Name Species Expression System
TMPY-02031 B7-H3 Protein, Human, Recombinant (His)

CD276 molecule,B7-H3,4Ig-B7-H3,B7...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-00674 B7-1 Protein, Human, Recombinant

CD28LG1,B7,CD80 molecule,LAB7,B7....

Human HEK293 Cells
B7-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is A0N0P2.
TMPY-04262 B7-H3 Protein, Human, Recombinant (His), Biotinylated

B7H3,4Ig-B7-H3,CD276 molecule,B7R...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-05641 B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated

4Ig-B7-H3,B7-H3,B7H3,CD276 molecu...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 49.8 kDa and the accession number is Q5ZPR3.
TMPY-03524 B7-H4 Protein, Human, Recombinant (His)

PRO1291,B7X,B7H4,B7-H4,VCTN1,...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL1,PDCD1LG1,B7H1,

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-04949 PD-L1 Protein, Human, Recombinant (His), Biotinylated

PDCD1LG1,B7H1,PD-L1,B7-H1,B7-H,CD...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1.
TMPY-04343 PD-L1 Protein, Human, Recombinant (His)

PDL1,B7-H,B7H1,PDCD1LG1,CD274 molecule,PD-...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1.
TMPK-00314 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

B7-H3,PSEC0249,PRO352, 4Ig-B7-H3,B7

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPK-01263 B7-H7 Protein, Cynomolgus, Recombinant (His)

B7H7,B7-H7,HHLA2,B7 Homolog 7

Cynomolgus HEK293 Cells
B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
TMPK-00315 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated

 4Ig-B7-H3,CD276,UNQ309,B7-H3,PRO352,PSEC0...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T...
TMPY-00643 B7-H3 Protein, Human, Recombinant (hFc)

B7RP-2,B7H3,B7-H3,4Ig-B7...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.3 kDa and the accession number is Q5ZPR3-1.
TMPY-05279 B7-H3 Protein, Human, Recombinant (hFc), Biotinylated

B7RP-2,B7-H3,CD276 molecule,B7H3,...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q5ZPR3-1.
TMPY-01063 B7-1 Protein, Human, Recombinant (His)

BB1,CD28LG1,B7-1,CD28LG,B7,B7.1,L...

Human HEK293 Cells
B7-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0N0P2.
TMPJ-00630 B7-1 Protein, Cynomolgus, Recombinant (hFc)

B7,CD80,T-lymphocyte activation antigen CD80,Activa...

Cynomolgus HEK293 Cells
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ...
TMPY-06298 B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated

CD28LG1,B7-1,B7.1,BB1,CD28LG,CD80 molecule...

Human HEK293 Cells
B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.12 kDa and the accession number is A0N0P2.
TMPY-01180 CD86 Protein, Human, Recombinant (His)

CD86 antigen,B70,B7.2,B7-2,CD28LG...

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPK-00280 B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated

NCR3LG1,B7H6,DKFZp686O24166,B7-H6,DKFZp686...

Human HEK293 Cells
B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
TMPY-05379 B7-1 Protein, Human, Recombinant (hFc)

B7-1,B7.1,LAB7,CD28LG,CD80 molecu...

Human HEK293 Cells
B7-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is A0N0P2.
TMPY-05016 HHLA2 Protein, Human, Recombinant (His)

HERV-H LTR-associating 2,HHLA2,B7-H7,B7H7

Human HEK293 Cells
HHLA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9UM44-1.
TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His)

Activation B7-1 antigen,T-lymphocyte activation ant...

Rabbit HEK293 Cells
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ...
TMPY-06581 B7-H3 Protein, Human, Recombinant (isoform 2, His)

CD276 molecule,B7H3,B7RP-2,4Ig-B7...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (isoform 2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.52 kDa and the accession number is Q5ZPR3-2.
TMPK-01017 B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)

B7H3,B7-H3,B7 homolog 3,PSEC0249,...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weig...
TMPK-01016 B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

B7H3, UNQ309,PRO352,PSEC0249,B7 homolog 3,...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular w...
TMPK-01018 B7-H3 Protein, Human, Recombinant (aa 29-245, His)

PRO352,B7H3, UNQ309,PSEC0249,CD276,B7-H3,<...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weig...
TMPK-00178 B7-1 Protein, Human, Recombinant (His & Avi)

B71,CD80,BB1,LAB7,B7-1,B7

Human HEK293 Cells
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. B7-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is P33681-1.
TMPK-00882 B7-2 Protein, Human, Recombinant (hFc)

B7-2,FUN-1,B7-2 antigen,CD86,LAB7...

Human HEK293 Cells
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag....
TMPY-04619 B7-H6 Protein, Human, Recombinant (His)

natural killer cell cytotoxicity receptor 3 ligand 1,DKFZp68...

Human HEK293 Cells
B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85.
TMPK-00653 B7-2 Protein, Cynomolgus, Recombinant (His)

B72,MGC34413,LAB72,B7-2,FUN-1,

Cynomolgus HEK293 Cells
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His...
TMPK-00880 B7-2 Protein, Human, Recombinant (His & Avi)

B70,B7-2 antigen,B7-2,CD86 molecu...

Human HEK293 Cells
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...
TMPJ-00959 B7-2 Protein, Rabbit, Recombinant (His)

CD86,T-lymphocyte activation antigen CD86,Activation B7<...

Rabbit HEK293 Cells
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
TMPY-00377 B7-H6 Protein, Human, Recombinant (hFc)

DKFZp686O24166,B7H6,B7-H6,natural killer c...

Human HEK293 Cells
B7-H6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.4 kDa and the accession number is Q68D85.
TMPK-00881 B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated

LAB72,B7-2,B7-2 antigen,FUN-1,CD8...

Human HEK293 Cells
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPY-06178 B7-H6 Protein, Human, Recombinant (His), Biotinylated

natural killer cell cytotoxicity receptor 3 ligand 1,B7<...

Human HEK293 Cells
B7-H6 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85.
TMPK-00179 B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated

B7.1,CD80,B7,CD80 molecule,CD28LG1,B7<...

Human HEK293 Cells
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is P33681-1.
TMPK-00172 B7-H4 Protein, Human, Recombinant (His & Avi)

B7H4,B7x,VTCN1,PRO1291,B7S1,B...

Human HEK293 Cells
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status .
TMPJ-00632 B7-2 Protein, Cynomolgus, Recombinant (hFc)

T-lymphocyte activation antigen CD86 isoform 1,Activation

Cynomolgus HEK293 Cells
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4.
TMPJ-00641 B7-2 Protein, Rhesus macaque, Recombinant (His)

Activation B7-2 antigen,T-lymphocyte activation ant...

Rhesus HEK293 Cells
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8.
TMPK-00192 B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)

B7RP1B7-like protein Gl50,B7-H2

Human HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...
TMPK-01264 B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)

B7H2,CD275,B7-H2,B7RP1B7...

Cynomolgus HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His...
TMPY-05280 B7-H4 Protein, Human, Recombinant (hFc), Biotinylated

B7S1,B7X,VCTN1,B7h.5,V-set domain...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1.
TMPY-04957 PD-L2 Protein, Human, Recombinant (His), Biotinylated

B7DC,Btdc,B7-DC,bA574F11.2,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPJ-00175 B7-H4 Protein, Rhesus macaque, Recombinant (hFc)

V-set domain containing T cell activation inhibitor 1,B7...

Rhesus HEK293 Cells
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the s...
TMPK-00193 B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated

B7H2,B7RP-1,ICOS ligand,GL50,B7-H...

Human HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPY-05080 B7-H4 Protein, Human, Recombinant (mFc)

B7H4,VCTN1,V-set domain containing T cell activatio...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q7Z7D3-1.
TMPY-03009 B7-H4 Protein, Human, Recombinant (hFc)

B7h.5,B7X,PRO1291,B7S1,B7

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,p...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-03219 VISTA Protein, Human, Recombinant (His)

DD1α,V-set immunoregulatory receptor,SISP1,DD1alpha,B7

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
TMPY-05322 B7-H4 Protein, Mouse, Recombinant (His)

BC032925,B7h4,B7x,V-set domain containing ...

Mouse HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5.
TMPK-01186 B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)

VSIR,B7H5,4632428N05Rik,SISP1,PP2135,Dies1,PD-1H,VI...

Human HEK293 Cells
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-H5/Gi24/VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 19 kDa and the accession number is Q9H7M9.
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重组蛋白

B7-H3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02031
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant
Cat.No: TMPY-00674
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04262
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05641
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03524
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04949
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04343
Species: Human
Expression System: HEK293 Cells
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00314
Species: Human
Expression System: HEK293 Cells
B7-H7 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01263
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00315
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00643
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05279
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01063
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00630
Species: Cynomolgus
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06298
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
Cat.No: TMPY-01180
Species: Human
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00280
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05379
Species: Human
Expression System: HEK293 Cells
HHLA2 Protein, Human, Recombinant (His)
Cat.No: TMPY-05016
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00958
Species: Rabbit
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (isoform 2, His)
Cat.No: TMPY-06581
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
Cat.No: TMPK-01017
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
Cat.No: TMPK-01016
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
Cat.No: TMPK-01018
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00178
Species: Human
Expression System: HEK293 Cells
B7-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00882
Species: Human
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (His)
Cat.No: TMPY-04619
Species: Human
Expression System: HEK293 Cells
B7-2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00653
Species: Cynomolgus
Expression System: HEK293 Cells
B7-2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00880
Species: Human
Expression System: HEK293 Cells
B7-2 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00959
Species: Rabbit
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00377
Species: Human
Expression System: HEK293 Cells
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00881
Species: Human
Expression System: HEK293 Cells
B7-H6 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-06178
Species: Human
Expression System: HEK293 Cells
B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated
Cat.No: TMPK-00179
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00172
Species: Human
Expression System: HEK293 Cells
B7-2 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00632
Species: Cynomolgus
Expression System: HEK293 Cells
B7-2 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00641
Species: Rhesus
Expression System: HEK293 Cells
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00192
Species: Human
Expression System: HEK293 Cells
B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01264
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05280
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04957
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00175
Species: Rhesus
Expression System: HEK293 Cells
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00193
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05080
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03009
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (His)
Cat.No: TMPY-03219
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05322
Species: Mouse
Expression System: HEK293 Cells
B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)
Cat.No: TMPK-01186
Species: Human
Expression System: HEK293 Cells
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