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57

抑制剂 & 化合物

20

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8734	Choline	Others	Others
	Choline hydroxide 是一种普遍存在的水溶性营养素，通常与 B 族维生素有关。
T8129	Potassium acetate Diuretic salt,Potassium ethanoate,乙酸钾	Antifungal	Microbiology/Virology
	Potassium acetate (Diuretic salt) 是一种钾盐，能够用于补充电解质，恢复水电解质平衡，也能用于制备细菌碱性裂解的中和液，以及纯化 DNA 和蛋白质。
T18888	4-Methylumbelliferyl phosphate 4-甲基伞形酮磷酸酯,4-MUP	Others	Others
	4-Methylumbelliferyl phosphate (4-MUP) 是碱性磷酸酶的荧光底物。
T1587	Exemestane EXE,依西美坦,FCE 24304,PNU155971	Aromatase	Endocrinology/Hormones
	Exemestane (EXE) 是一种选择性的、具有口服活性的、不可逆的甾体芳香酶抑制剂，能够作用于人胎盘芳香酶 (IC50:30 nM) 和大鼠卵巢芳香酶 (IC50:40 nM)，可用于研究激素依赖性乳腺癌。
T14280	AMPPD Lumigen PPD,3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane,PPD,Lumi-Phos Plus	Others	Others
	AMPPD (Lumi-Phos Plus) 是一种超敏碱性磷酸酶底物，是 1,2-dioxo-cyclohexane 衍生物。
T6353	(-)-p-Bromotetramisole Oxalate (-)-对溴四咪唑草酸盐,L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate	Phosphatase; Phosphorylase	Metabolism
	(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) 是一种强效的、非特异性碱性磷酸酶抑制剂。
T60254	Calcium glycerophosphate	Phosphorylase	Metabolism
	Calcium glycerophosphate(CaGP)是肠道碱性磷酸酶 F3 的抑制剂 (intestinal alkaline phosphatase F3)。Calcium glycerophosphate 可作为全肠外营养溶液中钙和磷的来源。
T0017	Phenolphthalein Euchessina,Phthalimetten,酚酞,Phthalin	Others	Others
	Phenolphthalein (Phthalin) 是一种广泛应用的指示剂染料，具有毒性。
T18923	BCIP 5-溴-4-氯-3-吲哚基磷酸酯对甲苯胺盐,BCIP p-toluidine salt,X-phosphate p-toluidine salt	Others	Others
	BCIP (BCIP p-toluidine salt) 是一种显色底物，可用于碱性磷酸酶活性的比色法检测。
T24821	Spizofurone Espizofurona,AG-629	Others	Others
	Spizofurone (Espizofurona) 具有抗溃疡活性，对大鼠胃黏膜具有保护作用，可增加分离的牛蛙十二指肠粘膜中的碱性分泌。
T16859	SBI-425	Others	Others
	SBI-425 是一种有效且具有口服生物利用度的 TNAP 抑制剂。 SBI-425 有效抑制脉管系统中的 TNAP，改善心血管参数和存活率，而骨骼没有检测到变化。
T0494	Tetramisole hydrochloride 盐酸四咪唑,R-829,DL-Tetramisole hydrochloride,(±)-Tetramisole hydrochloride,Tetramisole HCl	Phosphatase; Dehydrogenase; Antibiotic; Parasite	Metabolism; Microbiology/Virology
	Tetramisole hydrochloride (Tetramisole HCl) 抑制碱性磷酸酶, 是一种高纯度抗寄生虫药。
T16554	PNPP	Others	Others
	PNPP 是用于 ELISA 和常规分光光度测定的碱性和酸性磷酸酶的非蛋白质显色底物。
T0745	Disodium monofluorophosphate Sodium Monofluorophosphate,单氟磷酸钠,NSC248	Phosphatase; PKM; Phosphorylase	Metabolism
	Disodium monofluorophosphate (NSC248) 是丙酮酸激酶和碱性磷酸酶的竞争性抑制剂，它也不可逆地抑制磷酸化酶磷酸酶。
T11048L	DIPQUO hydrochloride DIPQUO hydrochloride(1269365-82-3 Free base)	Phosphorylase	Metabolism
	DIPQUO hydrochloride 是一种骨标记碱性磷酸酶 (ALP) 激活剂，在 C2C12 细胞中作用的 EC50 值为 6.27 μM。DIPQUO hydrochloride 通过激活 p38 MAPK-β 促进小鼠和人类的成骨细胞分化。
T67886	Girard's Reagent T Trimethylacetohydrazideammonium Chloride	Others	Others
	Girard's Reagent T (Trimethylacetohydrazideammonium Chloride) 是生化试剂。Girard's Reagent T 在温和的酸性或碱性条件下，与含有α-二羰基官能团的醛类和酮类反应，生成强吸收紫外线的加成化合物
T0192	Levetiracetam 左乙拉西坦,UCB L059,SIB-S1	DNA Methyltransferase; Others; Calcium Channel	Chromatin/Epigenetic; Membrane transporter/Ion channel; Metabolism; Others
	Levetiracetam (SIB-S1) 是一种化学增敏剂，增强 Temozolomide 对胶质母细胞瘤干细胞增殖和凋亡的影响。它调节 HDAC 水平，最终使 MGMT 沉默从而提高 Temozolomide 的有效性。它是一种抗癫痫药，可结合突触小泡蛋白 SV2A。
T21969	ML-095 hydrochloride CID-25067483 hydrochloride,MLS-0315848 hydrochloride	Phospholipase	Metabolism
	ML-095 hydrochloride (CID-25067483 hydrochloride) 是一种特异性胎盘碱性磷酸酶抑制剂。它抑制 PLAP、TNAP 和 IAP，IC50 分别为 2.1、>100 和 53 μM。
T20913	Light Green SF Yellowish Acid Green 5,C.I. Acid Green 5,C.I. 42095
	Light Green SF Yellowish (Acid Green 5) 是一种碱性染色剂，可用于动物组织染色，可用于植物组织学中作细胞质和纤维染色。
T8321	10-methyl-9-(phenoxycarbonyl) Acridinium	Others	Others
	10-methyl-9-(phenoxycarbonyl) Acridinium 是一种吖啶鎓酯，在碱性条件下与过氧化氢、过硫酸盐和其他氧化剂氧化后会产生荧光 10-methyl-9-acridone。
T34093	pNNP p NNP,p-Nitrophenyl phosphate,p-NNP,Nitrophenylphosphate	Carbonic Anhydrase	Metabolism
	pNNP (Nitrophenylphosphate) 可用作 PP2C 试验的底物。pNNP 对β-碳酸酐酶和α-碳酸酯脱水酶有抑制作用，对幽门螺杆菌幽门螺杆菌也具有抑制作用。pNNP 是一种活性较弱的组织非特异性碱性磷酸酶调节剂。
T19032	Nitro blue tetrazolium chloride NBT,氯化硝基四氮唑兰	NO Synthase	Immunology/Inflammation
	Nitro blue tetrazolium chloride (NBT) 是一种脱氢酶底物，能够与碱性磷酸酶底物 BCIP 一起用于 western blotting 和免疫组化染色。
T20421	Fluorescein diphosphate Fluorescein diphosphate Tetraammonium salt,FDP
	Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases. The sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluorescein monophosphate followed by stro
T11048	DIPQUO	Others	Others
	DIPQUO is an activator of bone marker alkaline phosphatase (ALP). DIPQUO promotes the differentiation of mouse and human osteoblasts by activating p38MAPK-β. The EC50 in C2C12 cells was 6.27 μM.
T25883	N-Retinoylphenylalanine N-Retinoyl-phe
	N-Retinoylphenylalanine is an inhibitor of alkaline phosphatase isoenzymes.
T25056	Alphostatin
	Alphostatin is an alkaline phosphatase inhibitor isolated from Bacillus megaterium.
T20544	C.I. 21010 C.I.-21010,C.I.21010
	C.I. 21010 is an alkaline dye.
T40593	5-FAM-Alkyne
	5-FAM-Alkyne is a highly selective and sensitive fluorescent biosensor designed for detecting alkaline phosphatase (ALP).
T37056	D-erythro-MAPP
	D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
TD0058	6-TRITC 四甲基罗丹明-6-异硫氰酸（单一化合物）,R isomer [Tetramethylrhodamine-6-isothiocyanate]
	6-TRITC can bind to various antibody proteins, and the antibody does not lose its specificity of binding to certain antigens, and has a strong yellow-green fluorescence in alkaline solution.
T38337	Isochlortetracycline
	Isochlortetracycline 是广谱抗生素金霉素降解的无活性碱性产物。
T75366	Naphthol AS-GR phosphate disodium
	Naphthol AS-GR phosphate disodium 为酸性及碱性磷酸酶底物，此化合物展现出强烈绿色荧光，广泛应用于组织化学研究中。
TD0057	5-TRITC G isomer [Tetramethylrhodamine-5-isothiocyanate],四甲基罗丹明-5-异硫氰酸（单一化合物）
	5-TRITC can bind to various antibody proteins, and the antibody does not lose its specificity of binding to certain antigens, and has a strong yellow-green fluorescence in alkaline solution.
T75349	CDP-Star
	CDP-Star 是碱性磷酸酶的化学发光底物。CDP-Star 可用于酶联免疫分析。
T75340	4-Methylumbelliferyl phosphate disodium
	4-Methylumbelliferyl phosphate disodium (4-MUP) 是一种阴离子有机磷酸酯，作为酸性和碱性磷酸酶（phosphatase）的荧光底物，同时也用作神经毒剂模拟剂。
T78386	4-Methylumbelliferyl oleate
	4-Methylumbelliferyl oleate是酸性及碱性脂肪酶的荧光底物，能被脂肪酶裂解，从而释放出4-Methylumbelliferyl（Ex/Em=320/450 nm）。
T11314	Fosmanogepix APX001,E1211	Others	Others
	Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections.
T63568	PLAP-IN-1
	PLAP-IN-1 是强效的、选择性的 PLAP 抑制剂，其 IC50值为32 nM，对组织非特异性碱性磷酸酶（TNAP）活性没有明显抑制效果。
T20104	C.I. 37545 NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes
	C.I. 37545 is also known as Azoic dyes. C.I. 37545 is impregnated cotton with an alkaline solution of β-naphthol, then treated it with a diazo solution obtained from aniline, a toluidine, xylidine, naphthylamine, aminoazobenzene or aminoazotoluene, so tha
T37616	Leukotriene A4 methyl ester Leukotriene A4 methyl ester
	白三烯A4甲酯可在大鼠肝脏中主要碱性胞质谷胱甘肽转移酶的催化下转化为白三烯C4单甲酯，可用于代谢相关研究。
T19390	L-Ascorbic acid 2-phosphate 维生素C磷酸酯,2-Phospho-L-ascorbic acid	Others	Others
	L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that can stimulate collagen formation and expression.
T35969	NOC-5
	NOC-5 is a stable nitric oxide (NO)-amine complex that acts as a NO donor. It can release two equivalents of NO in solution under physiological conditions without a cofactor. [1] The half-life of NOC-5 in PBS (pH 7.4) is 93 minutes at 22°C, and it remains relatively stable in alkaline solution (pH >=10.0). [1]
T69066	Forphenicine
	Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 µg/ml for the chicken intestine enzyme). It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 µM. Forphenicine (50 and 500 µg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).
T35777	Nodularin
	The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatotoxic monocylic pentapeptide produced by the N. spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. PP2B is inhibited to a lesser extent with an IC50 of 1.8 μM. No apparent inhibitory eff...
T36410	9(E),11(E),13(E)-Octadecatrienoic Acid
	9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces a...
T78924	TPE-1p
	TPE-1p为级联激活型AIEgen肽探针，具备在水溶液中自组装的能力，并对碱性磷酸酶（ALP）及ChT-L响应，展现出明亮的荧光。该探针适用于无创地评估ChT-L抑制剂在细胞内的抑制效能。
T75377	Thymolphthalein monophosphate disodium hydrate
	Thymolphthalein monophosphate disodium hydrate 是用于测定酸性及碱性磷酸酶显色底物。反应过程中释放的百里酚酞可增加介质pH，促使颜色产生并终止水解作用，特别适合于血清中前列腺磷酸酶的特异性检测。
T36714	Sucrose octasulfate (potassium salt)
	Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 μM) and inhibit its catalytic activity (IC50 = 4.5 μM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by pr...
T76660	pTH (1-37) (human)
	pTH (1-37) (human) 为甲状旁腺激素（PTH）的一段，能诱导cAMP产生并提升碱性磷酸酶活性，进而增强尿毒症动物的生长速度、骨钙含量及骨矿物质密度（BMD），显示出对骨质疏松症研究的应用潜力。
T82147	Hydroxy naphthol blue disodium
	Hydroxy naphthol blue disodium 作为一种钙离子金属指示剂和碱土金属离子比色试剂(λmax = 650 nm)，在pH值介于12至13的环境中表现出明显的颜色变化；该指示剂在钙离子存在时显淡红色，在EDTA二钠作用下则转为深蓝色。

化合物

Cat.No: T8734

Target: Others

Potassium acetate

Cat.No: T8129

Synonym: Diuretic salt,Potassium ethanoate,乙酸钾

Target: Antifungal

4-Methylumbelliferyl phosphate

Cat.No: T18888

Synonym: 4-甲基伞形酮磷酸酯,4-MUP

Target: Others

Cat.No: T1587

Synonym: EXE,依西美坦,FCE 24304,PNU155971

Target: Aromatase

Cat.No: T14280

Synonym: Lumigen PPD,3-(2'-Spiroadamantane)-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane,PPD,Lumi-Phos Plus

Target: Others

(-)-p-Bromotetramisole Oxalate

Cat.No: T6353

Synonym: (-)-对溴四咪唑草酸盐,L-p-Bromotetramisole oxalate,6-Bromolevamisole oxalate,(-)-p-Bromolevamisole oxalate

Target: Phosphatase, Phosphorylase

Calcium glycerophosphate

Cat.No: T60254

Target: Phosphorylase

Phenolphthalein

Cat.No: T0017

Synonym: Euchessina,Phthalimetten,酚酞,Phthalin

Target: Others

Cat.No: T18923

Synonym: 5-溴-4-氯-3-吲哚基磷酸酯对甲苯胺盐,BCIP p-toluidine salt,X-phosphate p-toluidine salt

Target: Others

Cat.No: T24821

Synonym: Espizofurona,AG-629

Target: Others

Cat.No: T16859

Target: Others

Tetramisole hydrochloride

Cat.No: T0494

Synonym: 盐酸四咪唑,R-829,DL-Tetramisole hydrochloride,(±)-Tetramisole hydrochloride,Tetramisole HCl

Target: Phosphatase, Dehydrogenase, Antibiotic, Parasite

Cat.No: T16554

Target: Others

Disodium monofluorophosphate

Cat.No: T0745

Synonym: Sodium Monofluorophosphate,单氟磷酸钠,NSC248

Target: Phosphatase, PKM, Phosphorylase

DIPQUO hydrochloride

Cat.No: T11048L

Synonym: DIPQUO hydrochloride(1269365-82-3 Free base)

Target: Phosphorylase

Girard's Reagent T

Cat.No: T67886

Synonym: Trimethylacetohydrazideammonium Chloride

Target: Others

Cat.No: T0192

Synonym: 左乙拉西坦,UCB L059,SIB-S1

Target: DNA Methyltransferase, Others, Calcium Channel

ML-095 hydrochloride

Cat.No: T21969

Synonym: CID-25067483 hydrochloride,MLS-0315848 hydrochloride

Target: Phospholipase

Light Green SF Yellowish

Cat.No: T20913

Synonym: Acid Green 5,C.I. Acid Green 5,C.I. 42095

10-methyl-9-(phenoxycarbonyl) Acridinium

Cat.No: T8321

Target: Others

Cat.No: T34093

Synonym: p NNP,p-Nitrophenyl phosphate,p-NNP,Nitrophenylphosphate

Target: Carbonic Anhydrase

Nitro blue tetrazolium chloride

Cat.No: T19032

Synonym: NBT,氯化硝基四氮唑兰

Target: NO Synthase

Fluorescein diphosphate

Cat.No: T20421

Synonym: Fluorescein diphosphate Tetraammonium salt,FDP

Cat.No: T11048

Target: Others

N-Retinoylphenylalanine

Cat.No: T25883

Synonym: N-Retinoyl-phe

Cat.No: T25056

Cat.No: T20544

Synonym: C.I.-21010,C.I.21010

Cat.No: T40593

Cat.No: T37056

Cat.No: TD0058

Synonym: 四甲基罗丹明-6-异硫氰酸（单一化合物）,R isomer [Tetramethylrhodamine-6-isothiocyanate]

Isochlortetracycline

Cat.No: T38337

Naphthol AS-GR phosphate disodium

Cat.No: T75366

Cat.No: TD0057

Synonym: G isomer [Tetramethylrhodamine-5-isothiocyanate],四甲基罗丹明-5-异硫氰酸（单一化合物）

Cat.No: T75349

4-Methylumbelliferyl phosphate disodium

Cat.No: T75340

4-Methylumbelliferyl oleate

Cat.No: T78386

Cat.No: T11314

Synonym: APX001,E1211

Target: Others

Cat.No: T63568

Cat.No: T20104

Synonym: NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes

Leukotriene A4 methyl ester

Cat.No: T37616

Synonym: Leukotriene A4 methyl ester

L-Ascorbic acid 2-phosphate

Cat.No: T19390

Synonym: 维生素C磷酸酯,2-Phospho-L-ascorbic acid

Target: Others

Cat.No: T35969

Cat.No: T69066

Cat.No: T35777

9(E),11(E),13(E)-Octadecatrienoic Acid

Cat.No: T36410

Cat.No: T78924

Thymolphthalein monophosphate disodium hydrate

Cat.No: T75377

Sucrose octasulfate (potassium salt)

Cat.No: T36714

pTH (1-37) (human)

Cat.No: T76660

Hydroxy naphthol blue disodium

Cat.No: T82147

Cat. No.	Product Name	Target	Signaling Pathways
T35951	Alkaline Phosphatase	Others	Others
	Alkaline phosphatase 是一种膜结合糖蛋白，在碱性条件下可催化磷酸单酯的水解。它可用于分子生物学和酶免分析。
TN1124	Neoeriocitrin	AChE	Neuroscience
	Neoeriocitrin 是一种有效的乙酰胆碱酯酶抑制剂，分离于自百日草，在 MC3T3-E1 中显示出对增殖和成骨分化的活性。
T4852	Trimyristin Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol	Phosphatase; Endogenous Metabolite; AChE	Metabolism; Neuroscience
	Trimyristin (Tritetradecanoin) 是一种 Myristica fragransHoutt 的有效成分，能够显著抑制乙酰胆碱酯酶 (AChE)，酸性和碱性磷酸酶 (ACP/ALP) 特性。它对 AChE，ACP 和 ALP 的 IC50分别为 0.11、0.16 和 0.18 mM。
T8103	H-HoArg-OH	Endogenous Metabolite; Phosphorylase	Metabolism
	H-HoArg-OH 是人骨和肝脏碱性磷酸酶(alkaline phosphatase)的强效抑制剂，是一种精氨酸的同系物。
T3938	H-HomoArg-OH.HCl NSC 145416,L-Homoarginine hydrochloride,L-高精氨酸盐酸盐,L(+)-Homoarginine hydrochloride	Endogenous Metabolite; Phosphorylase	Metabolism
	H-HomoArg-OH.HCl (L-Homoarginine hydrochloride) 是内源性代谢产物的一种。
T18930	Bromothymol Blue	Others	Others
	Bromothymol Blue 是 pH 指示剂，在测定弱酸弱碱时使用，在酸性条件下为黄色，在碱性条件下为蓝色。
T3855	Tracheloside	Estrogen Receptor/ERR; Phosphorylase	Endocrinology/Hormones; Metabolism
	Tracheloside 是抗雌激素木质素，利用 ERK1/2 刺激促进角质形成细胞增殖，是一种良好的促进伤口愈合的药物。
TN7243	Fallaxsaponin A
	Fallaxsaponin A 是从远志中总皂苷的碱性水解产物中分离出来的。
T5244	Aminomalonic acid 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate	Others; Endogenous Metabolite	Metabolism; Others
	Aminomalonic acid (Aminomalonate) 是氨基内源性代谢产物，在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的 L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M，小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。
T6S0071	Fraxinellone	HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
	Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物，是PD-L1抑制剂，可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1，有用于癌症免疫的潜力。
T2133	Adenosine monophosphate 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate	Endogenous Metabolite; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Adenosine monophosphate (AMP) 是一种嘌呤核糖核苷5'-单磷酸腺苷，是信号转导和调节能量稳态的关键细胞代谢物。它具有EC 3.1.3.11(果糖-二磷酸酶)抑制剂、EC 3.1.3.1(碱性磷酸酶)抑制剂和腺苷A1受体激动剂的作用。
T10109	3-Carene Delta-3-Carene	COX; Antifungal	Immunology/Inflammation; Microbiology/Virology; Neuroscience
	3-Carene（Delta-3-Carene）是西部落叶松和花旗松中提取的双环单萜烯，可做为植物杀菌剂。3-Carene 对痛觉刺激引起的炎症浸润和 COX-2 过表达有抑制作用。3-Carene 具有抗伤害作用，能促进成骨细胞分化的早期标志物碱性磷酸酶的活性和表达。
TN6926	Paeonoside	Others	Others
	Paeonoside 发现与P. suffruticosa 中，具有生物活性，可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性，可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用，以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶（ALP）染色及其活性。
T4723	D-Tagatose 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos	Others; Endogenous Metabolite	Metabolism; Others
	D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖，具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物，也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品，也是口香糖、果汁和饮料等食品中的低热量甜味剂。
TN3215	7,4'-Dihydroxy-8-methylflavan	Others	Others
	7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 7,4'-Dihydroxy-8-methylflavan also has free radical scavenging properties.
T14368	Azadirachtin B	Others	Others
	Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and osteogenic effects. It is effective against the Epstein-Barr virus early antigen (EBV-EA), enhances alkaline phosphatase (ALP) activity, and promotes osteoblast differentiation[1][2][3].
TN3380	Alloisoimperatorin	AChR	Neuroscience
	Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoimperatorin has estrogenic activity
T81428	Polypectate sodium pectate sodium
	Polypectate sodium作为细胞壁多糖（果胶）的关键组分，充当碳源及多聚半乳糖醛酸酶诱导剂。此外，Polypectate sodium适用于评估链霉菌属果胶酸裂解酶的碱性活性与稳定性，同时用于黄腐藻多聚半乳糖醛酸酶生产及反应条件的优化研究。
TN4999	Serratenediol	BCL; PARP; Caspase	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote
T35415	α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
	α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...

天然产物

Alkaline Phosphatase

Cat.No: T35951

Target: Others

Cat.No: TN1124

Target: AChE

Cat.No: T4852

Synonym: Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol

Target: Phosphatase, Endogenous Metabolite, AChE

Cat.No: T8103

Target: Endogenous Metabolite, Phosphorylase

H-HomoArg-OH.HCl

Cat.No: T3938

Synonym: NSC 145416,L-Homoarginine hydrochloride,L-高精氨酸盐酸盐,L(+)-Homoarginine hydrochloride

Target: Endogenous Metabolite, Phosphorylase

Bromothymol Blue

Cat.No: T18930

Target: Others

Cat.No: T3855

Target: Estrogen Receptor/ERR, Phosphorylase

Fallaxsaponin A

Cat.No: TN7243

Aminomalonic acid

Cat.No: T5244

Synonym: 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate

Target: Others, Endogenous Metabolite

Cat.No: T6S0071

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Adenosine monophosphate

Cat.No: T2133

Synonym: 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate

Target: Endogenous Metabolite, AMPK

Cat.No: T10109

Synonym: Delta-3-Carene

Target: COX, Antifungal

Cat.No: TN6926

Target: Others

Cat.No: T4723

Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Target: Others, Endogenous Metabolite

7,4'-Dihydroxy-8-methylflavan

Cat.No: TN3215

Target: Others

Cat.No: T14368

Target: Others

Alloisoimperatorin

Cat.No: TN3380

Target: AChR

Polypectate sodium

Cat.No: T81428

Synonym: pectate sodium

Cat.No: TN4999

Target: BCL, PARP, Caspase

α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

Cat.No: T35415

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