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47

抑制剂 & 化合物

14

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T6483	EHT 1864 EHT 1864 2HCl	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	EHT 1864 是 Rac 家族 GTPase 抑制剂，对 Rac1、Rac1b、Rac2 和 Rac3的Kd 为 40、50、60 和 250 nM。
T4060	Acelarin N-(2'-脱氧-2',2'-二氟-P-苯基-5'-胞苷酰)-L-丙氨酸苄酯,NUC-1031	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Acelarin (NUC-1031) 是核苷类似物吉西他滨的 ProTide 改造和增强产品。
T31425	Dibenz[a,h]anthracene CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A	DNA	DNA Damage/DNA Repair
	Dibenz[a,h]anthracene (CCRIS 208) 诱导细菌DNA 损伤和基因突变，并在几种哺乳动物细胞培养物中诱导基因突变和转化。
T25284	DAC-2-25 DAC 225,DAC-225,DAC 2 25	Others	Others
	DAC-2-25是 Hydra 头部再生调节剂。它通过诱导 Hydra 的同源转化而起作用。
T13166	TK216	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	TK216 是一种口服有效的 E26 转录因子抑制剂，具有抗癌活性。它直接结合 EWS-FLI1 并抑制 EWS-FLI1 蛋白质相互作用，也可阻止 EWS-FLI1 与 RNA 解旋酶 A 的结合。
T5983	o-Phenanthroline 1,10-菲罗啉,1,10-Phenanthroline	MMP; Others	Others; Proteases/Proteasome
	o-Phenanthroline (1,10-Phenanthroline) 是一种金属螯合剂，能够与 Fe2+形成红色螯合物，在 510 nm 处最大吸收，可防止链脲佐菌素诱导染色体畸变。它也是一种MMP 的抑制剂。
T33762	Fosifloxuridine nafalbenamide NUC-3373,NUC3373,NUC 3373	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Fosifloxuridine nafalbenamide (NUC 3373) 是一种胸腺嘧啶合酶抑制剂，属于嘧啶核苷酸类似物，具有抗癌活性。它能诱发宿主免疫反应，有潜力增强免疫治疗。
T50110	CD532	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	CD532 是一种高效的 Aurora A 激酶抑制剂，IC50 值为 45 nM。CD532 可阻断 Aurora A 激酶活性，驱动 MYCN 降解，可以直接与 AURKA 相互作用并诱导整体构象转变。CD532 可用于研究癌症。
T6017	Linsitinib OSI-906,林西替尼	IGF-1R	Tyrosine Kinase/Adaptors
	Linsitinib (OSI-906) 是选择性的、有效的、具有口服活性的IGF-1和胰岛素受体(IR)的双重抑制剂，IC50分别为 35 和 75 nM。
T68405	KW-2450 free base	IGF-1R	Tyrosine Kinase/Adaptors
	KW-2450 free base 是一种 IGF-1R/IR和酪氨酸激酶多重抑制剂具有抗肿瘤活性。KW-2450 free base 在小鼠 HT-29/GFP 结肠癌异种移植模型中显示出适度的生长抑制活性并抑制 IGF-1 诱导的信号转导。
T4013	SGC2085 HCl	Histone Methyltransferase	Chromatin/Epigenetic
	SGC2085 HCl 是一种有效的选择性辅激活剂相关的精氨酸甲基转移酶 1 (CARM1) 抑制剂，IC50 为 50 nM，选择性比其他 PRMT 高出数倍。 CARM1 是结直肠癌中 Wnt/β-catenin 转录和肿瘤转化的重要正调节因子，也是雌激素刺激的乳腺癌生长的关键因素，其耗竭导致体内髓性白血病细胞增殖减少。
T32464	L 685487 13-Desmethyl FR 900520,L685487,L-685487
	L 685487 is produced by microbial transformation of FR 900520.
TP2437	Sarasinoside A1 Sarasinoside-A1
	Sarasinoside A1 is a triterpenoid saponin that reverses mesenchymal tumor transformation.
T71562	Boxidine
	Boxidine inhibits the transformation of 7-dehydrocholesterol to cholesterol & also inhibits sterol absorption.
T14295	Antipain	Others	Others
	Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations[1][2].
T20755	Trimegestone RU27987,RU-27987,RU 27987
	Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation.
T26836	BLL5 Maleate
	BLL5 Maleate is a first-in-class selective PRMT5 inhibitor, it blocks EBV-driven B lymphocyte transformation and survival while leaving normal B cells unaffected.
T24513	MYRA-A NSC-339585,NSC 339585,NSC339585
	MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.
T38704	2-Bromo-6-nitrophenol
	2-Bromo-6-nitrophenol undergoes transformation into 2-bromo-6-aminophenol, which is subsequently converted to N-acetyl-2-bromo-6-aminophenol.
T74208	Pyrocholecalciferol
	Pyrocholecalciferol 一种维生素 D 类似物，由 7-脱氢胆固醇 (7-DHC) 的光化学转化产生。
T21676	SCH 51344
	SCH 51344 抑制Ras 诱导的恶性转化。SCH 51344可防止癌基因转化的成纤维细胞的非锚定生长。
T68755	NZ-28
	NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis.
T37459	Lipoxin A5
	Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes. LXA5 slowly contracts pulmonary parenchymal strips from guinea pig with similar potency to that of LXA4 and LXB4. However, LXA5 does not exert the vasodilatory effects on aortic smooth muscle exhibited by LXA4 and LXB4.
T76164	Lipoxygenase, general
	Lipoxygenase, general (LOX) 是一种在生化研究中常用的双加氧酶，它能催化如亚油酸和花生四烯酸等多不饱和脂肪酸，生成相应的氢过氧化物。
T71837	HBX
	HBX is a deubiquitinase inhibitor. It inhibits HAdV type 5 (species C, HAdV-C5) replication and oncogenic transformation through inhibition of the cellular pro-viral factor ubiquitin-specific protease 7 (USP7). HBX also significantly inhibits virus genome replication and progeny release of all adenovirus types tested, with the exception of types 12 and 31, from tested species.
T39175	CSP1
	CSP1 is a highly potent and selective agonist of the ComD1 receptor, exhibiting an IC50 value of 10.3 nM. It represents a major variant of competence-stimulating peptide (CSP) and plays a crucial role in regulating the genetic transformation of S. pneumoniae through modulation of quorum sensing (QS). Additionally, CSP1 possesses antibacterial activity, further enhancing its potential as an effective antibacterial agent.
T73756	Galactonic acid
	Galactonic acid 是半乳糖代谢中的一种糖酸，通过半乳糖脱氢酶作用，半乳糖转化为半乳糖内酯，随后经自发或酶催化反应转化为 Galactonic acid。
T69051	Aculeacin A
	Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomyces cerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A is a lipopeptide that inhibits β-glucan synthesis in yeasts. The inhibition is due to the selective blockage of glucan synthase. Aculeacin A, an amphophilic antibiotic, inhibits the biosynthesis of β−glucan by selective blockage of β(1→3) glucan synthase.
T36606	(±)7-HDHA
	(±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells and human neutrophils also produces 7-HDHA. However, the enzymatic product is most likely the S-isomer. (±)7-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
T74009	1,1,3-Tribromoacetone
	1,1,3-Tribromoacetone 是甲氨蝶呤的杂质。Methotrexate (Amethopterin) 是一种抗代谢 (antimetabolite) 和抗叶酸剂 (antifolate)，可抑制二氢叶酸还原酶，从而防止叶酸转化为四氢叶酸并抑制 DNA 合成。
T76141	Bilirubin oxidase
	Bilirubin oxidase (BOD) 为一多铜氧化酶，能催化胆红素氧化为胆绿素，同时将分子氧还原成水。该酶在卟啉及叶绿素代谢中起作用，并作为氧还原催化剂在生化研究中广泛应用。
T82006	JM3A
	JM3A为高特异性生物活性肽，针对早期肺癌细胞转化过程中新表达的细胞表面波形蛋白(CSV)。通过与荧光团耦合，JM3A能够检测并标记CSV。
T36602	(±)4-HDHA
	(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells also produces 4-HDHA. However, the enzymatic product is most likely the S-isomer. (±)4-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
T75403	Glucuronokinase (AtGlcAK)
	Glucuronokinase (AtGlcAK) 为GHMP激酶家族的一员。其对D-葡萄糖醛酸表现出独有的底物特异性，具有0.7 mM的Km值。Glucuronokinase (AtGlcAK) 能催化D-葡萄糖醛酸与ATP反应生成D-葡萄糖醛酸-1-磷酸和ADP。
T76151	Glycerol kinase
	Glycerol kinase (GyK) 甘油激酶是一种细菌糖激酶，常用于生化研究。Glycerol kinase 通过将三醇转化为甘油-3-p (G3P) 来催化甘油代谢。Glycerol kinase 对于调节细胞中不依赖通道/促进因子的甘油摄取至关重要。
T81526	Pegsebrenatide NLY01
	Pegsebrenatide (NLY01) 是一种具有扩展半衰期和优良血脑屏障穿透能力的长效GLP-1R激动剂。该化合物能够抑制A1型星形胶质细胞的活化，降低多巴胺能神经元凋亡，并在帕金森病（PD）小鼠模型中改善运动功能障碍。
T69055	PD153035 nitrate
	PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also...
T80218	GAD65(247-266) epitope TFA	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	GAD65(247-266) epitope TFA 为T细胞表位，与I-Ag7（I型糖尿病相关分子）竞争性结合，亲和力较低。该表位源自胰岛抗原，GAD65 是谷氨酸脱羧酶 65，涉及将谷氨酸转换为γ-氨基丁酸（GABA）。
T76147	3α-Hydroxysteroid dehydrogenase
	3α-Hydroxysteroid dehydrogenase(3α-HSD) 是一种由 AKR1C4 基因编码的酶，可以催化 3-酮类甾体转化为 3α-羟基化合物。3α-Hydroxysteroid dehydrogenase 在雄激素 DHT 的失活中起重要作用，可以将 DHT 转化成雄激素活性很弱的 3α-雄烷二醇，可用于多毛症研究。
T70876	KW-2450 Tosylate
	KW-2450 Tosylate is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 Tosylate selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in t...
T60699	Aditoprime
	Aditoprime (Aditoprim) 是细菌二氢叶酸还原酶(DHFR)的选择性抑制剂。Aditoprime 抑制二氢叶酸向四氢叶酸的转化。Aditoprime 显示出良好的抗菌活性，具有广谱抗菌性，并且显示出良好的药代动力学。Aditoprime 抑制干酪乳杆菌和大肠杆菌 DHFR 的 IC50分别为520和47 nM。
T36836	(4′-Hydroxy)phenoxybenzoic Acid
	(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2 1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988)
T36205	Methylcarbamyl PAF C-16
	Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in platelet-rich plasma. In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc and c-fos and the activation of mitogen-activated protein kinase. Methy...
T22552	AD57 (hydrochloride)	Others	Others
	AD57, as polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer blocks the receptor tyrosine kinase RET in Drosophila (IC50: 2 nM). AD57 effectively suppresses tyrosine kinase RET, weakens the activity of numero
T63902	XP-524
	XP-524 是 BET 和 EP300 的有效抑制剂。 XP-524 在体内具有显著的杀肿瘤作用，能够阻止 KRAS 诱导的体内肿瘤转化，并延长两种侵袭性 PDAC 转基因小鼠模型的存活时间。XP-524 也提高了自身肽的表达及将肿瘤细胞向细胞毒性 T 淋巴细胞的募集。XP-524 对胰腺导管腺癌（PDAC）表现出研究潜力。
T83819	2'-O-Methylguanosine-5'-O-triphosphate sodium 2'-methyl GTP,2'-O-methyl GTP
	2’-O-甲基鸟苷-5'-O-三磷酸（2’-methyl GTP）作为丙肝病毒（HCV）非结构蛋白5B（NS5B；IC50 = 3.5 µM）的抑制剂，同时是前药IDX184的活性代谢产物，通过2’-methylguanosine中间体生成。在50 µM浓度下，2’-methyl GTP还能促进微管蛋白聚合。患有肝细胞癌的患者体内2’-methyl GTP水平，相比于邻近正常组织有所下降。
T38263	TBK1/IKKε-IN-4 TBK1/IKKε-IN-4
	TBK1/IKKε-IN-4 is a 6-aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKKε inhibitor with IC50 values of 13 nM and 59 nM, respectively. TBK1/IKKε-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family members and mTOR[1]. TBK1/IKKε-IN-4 (Compound II; 96 hours; A549 andHCC44 cells) treatmentdisplays selective toxicity in TBK1-dependent cancer cell lines (IC50 of ~ 4.2 μM for H441 cells and IC50 of ~0.4 μM for A549 cells)[1].TBK1/IK...

化合物

Cat.No: T6483

Synonym: EHT 1864 2HCl

Target: Rho, Ras

Cat.No: T4060

Synonym: N-(2'-脱氧-2',2'-二氟-P-苯基-5'-胞苷酰)-L-丙氨酸苄酯,NUC-1031

Target: DNA/RNA Synthesis

Dibenz[a,h]anthracene

Cat.No: T31425

Synonym: CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A

Target: DNA

Cat.No: T25284

Synonym: DAC 225,DAC-225,DAC 2 25

Target: Others

Cat.No: T13166

Target: Others, DNA/RNA Synthesis

o-Phenanthroline

Cat.No: T5983

Synonym: 1,10-菲罗啉,1,10-Phenanthroline

Target: MMP, Others

Fosifloxuridine nafalbenamide

Cat.No: T33762

Synonym: NUC-3373,NUC3373,NUC 3373

Target: DNA/RNA Synthesis

Cat.No: T50110

Target: Aurora Kinase

Cat.No: T6017

Synonym: OSI-906,林西替尼

Target: IGF-1R

KW-2450 free base

Cat.No: T68405

Target: IGF-1R

Cat.No: T4013

Target: Histone Methyltransferase

Cat.No: T32464

Synonym: 13-Desmethyl FR 900520,L685487,L-685487

Sarasinoside A1

Cat.No: TP2437

Synonym: Sarasinoside-A1

Cat.No: T71562

Cat.No: T14295

Target: Others

Cat.No: T20755

Synonym: RU27987,RU-27987,RU 27987

Cat.No: T26836

Cat.No: T24513

Synonym: NSC-339585,NSC 339585,NSC339585

2-Bromo-6-nitrophenol

Cat.No: T38704

Pyrocholecalciferol

Cat.No: T74208

Cat.No: T21676

Cat.No: T68755

Cat.No: T37459

Lipoxygenase, general

Cat.No: T76164

Cat.No: T71837

Cat.No: T39175

Galactonic acid

Cat.No: T73756

Cat.No: T69051

Cat.No: T36606

1,1,3-Tribromoacetone

Cat.No: T74009

Bilirubin oxidase

Cat.No: T76141

Cat.No: T82006

Cat.No: T36602

Glucuronokinase (AtGlcAK)

Cat.No: T75403

Glycerol kinase

Cat.No: T76151

Cat.No: T81526

Synonym: NLY01

PD153035 nitrate

Cat.No: T69055

GAD65(247-266) epitope TFA

Cat.No: T80218

Target: GABA Receptor

3α-Hydroxysteroid dehydrogenase

Cat.No: T76147

KW-2450 Tosylate

Cat.No: T70876

Cat.No: T60699

(4′-Hydroxy)phenoxybenzoic Acid

Cat.No: T36836

Methylcarbamyl PAF C-16

Cat.No: T36205

AD57 (hydrochloride)

Cat.No: T22552

Target: Others

Cat.No: T63902

2'-O-Methylguanosine-5'-O-triphosphate sodium

Cat.No: T83819

Synonym: 2'-methyl GTP,2'-O-methyl GTP

TBK1/IKKε-IN-4

Cat.No: T38263

Synonym: TBK1/IKKε-IN-4

Cat. No.	Product Name	Target	Signaling Pathways
T2987	(-)-Epigallocatechin 表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC	MMP; Autophagy	Autophagy; Proteases/Proteasome
	(-)-Epigallocatechin (Epigallocatechin) 是绿茶中含量最丰富的黄酮类天然产物，可与未折叠的天然多肽结合，阻止转化为淀粉样蛋白原纤维。
T3S1513	(20R)-Protopanaxadiol Protopanaxadiol,20R-Protopanaxadiol,(20R)-原人参二醇,(20R)-Protopanaxdiol	Others; Antibacterial	Microbiology/Virology; Others
	(20R)-Protopanaxadiol ((20R)-Protopanaxdiol) 是黑参中20(R)-人参皂甙 Rg3的一种三萜皂苷代谢物。它抑制幽门螺杆菌的生长，有抗肿瘤活性和细胞毒性。
TN2063	Physalin B NSC-287088	Apoptosis; NF-κB; Akt; PI3K; Nrf2; NOD	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
	Physalin B 是茄科植物的主要活性化合物之一，具有广泛的生物活性，可用于治疗炎症湿疹和疱疹等疾病。Physalin B 通过激活 PI3K/Akt 通路抑制 NF-κB 和 NLRP3，从而改善脂多糖诱导的急性肺损伤造成的炎症反应。Physalin B 通过激活 Nrf2 通路抑制 PDGF-BB 诱导的 VSMC 增殖、迁移和表型转化。Physalin B 通过抑制 LAP2α-HDAC1 介导的胶质瘤相关癌基因 1 的去乙酰化和肝星状细胞活化来发挥抗肿瘤活性。
T4703	(2-Aminoethyl)phosphonic acid 2-Aminoethylphosphonic acid,2-氨基乙基膦酸,Ciliatine,2-AEP	Others; Endogenous Metabolite	Metabolism; Others
	(2-Aminoethyl)phosphonic acid (2-Aminoethylphosphonic acid) 主要在尿液中检测到。(2-Aminoethyl)phosphonic acid 参与许多酶促反应，也是其他转化产物的母体化合物，包括但不限于神经酰胺 2-(甲氨基)乙基膦酸酯、N-(2-膦乙基)胆酰胺和 CMP-2-氨基乙基膦酸酯。
T5S0018	Betulonic acid 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite; HSV	Microbiology/Virology
	Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物，具有抗肿瘤，抗炎，抗寄生虫和抗病毒的活性。
T4861	trans-Aconitic acid	ATPase; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	trans-Aconitic acid 是反式丙酮酸2-甲基转移酶的底物，存在于正常人尿液中，大量存在于 Reye 综合征和有机酸尿症。
T4855	Tricosanoic acid Tricosan-1-oic acid,二十三烷酸	Endogenous Metabolite	Metabolism
	Tricosanoic acid (Tricosan-1-oic acid) 是毛发生长激活剂，是长链脂肪酸。
T3S0013	Ethyl trans-caffeate 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester	Others	Others
	Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) 具有抗炎作用。它是一种有前途的天然化合物，未来在慢性肝病中的应用。它是一种有效的化学预防化合物，可防止因太阳紫外线照射引起的皮肤癌变。它是与人胰腺α-淀粉酶复合的代表性抑制剂的高分辨率结构。它强烈抑制 JB6 Cl41细胞的肿瘤转化，无毒性。 PI3K、ERK1/2 和 p38 激酶活性在体外通过与 HOEC 直接结合而受到抑制。
TN4014	Esculentoside B	Antifection	Microbiology/Virology
	Phytolaccoside B(Esculentoside B) is an antifungal monodesmoside triterpenoid glycoside, it has potent inhibitory activity against agrobacterial plant transformation.
TN6651	Picrasidine Q
	Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
T83362	3-epi-Bufalin
	3-epi-Bufalin (化合物2a) 是一种从蟾蜍二烯内酯通过微生物转化得到的产物。
T83804	5-(3'-Hydroxyphenyl)-γ-Valerolactone (3’-hydroxy)-PVL,δ-(3’-Hydroxyphenyl)-γ-VL,5-(3’-Hydroxyphenyl)-γ-VL,δ-(3’-Hydroxyphenyl)-γ-Valerolactone
	5-(3'-羟基苯基)-γ-戊内酯是多种多酚的代谢产物，包括(+)-儿茶素和(−)-表儿茶素。这种化合物由肠道微生物从这些多酚中形成。
TN3979	Epiyangambin	PAFR	GPCR/G Protein
	Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using 24-well plates. Epiyangambin exhibits significant inhibition of the transformation of murine epidermal JB6 cells, with the IC50 value of 0.15 microg/mL. (+)-Epiyangambin also has anti-platelet aggregation activity.
T82445	Erinacine P
	Erinacine P（化合物1）为担子菌猴头菇YB4-6237菌丝体分离得到的木犀草素亲代代谢产物。其在温和条件下可化学转化为猴头素B，继而可转化为猴头素A。

天然产物

(-)-Epigallocatechin

Cat.No: T2987

Synonym: 表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC

Target: MMP, Autophagy

(20R)-Protopanaxadiol

Cat.No: T3S1513

Synonym: Protopanaxadiol,20R-Protopanaxadiol,(20R)-原人参二醇,(20R)-Protopanaxdiol

Target: Others, Antibacterial

Cat.No: TN2063

Synonym: NSC-287088

Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD

(2-Aminoethyl)phosphonic acid

Cat.No: T4703

Synonym: 2-Aminoethylphosphonic acid,2-氨基乙基膦酸,Ciliatine,2-AEP

Target: Others, Endogenous Metabolite

Cat.No: T5S0018

Synonym: 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Target: Parasite, HSV

trans-Aconitic acid

Cat.No: T4861

Target: ATPase, Endogenous Metabolite

Tricosanoic acid

Cat.No: T4855

Synonym: Tricosan-1-oic acid,二十三烷酸

Target: Endogenous Metabolite

Ethyl trans-caffeate

Cat.No: T3S0013

Synonym: 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester

Target: Others

Esculentoside B

Cat.No: TN4014

Target: Antifection

Cat.No: TN6651

Cat.No: T83362

5-(3'-Hydroxyphenyl)-γ-Valerolactone

Cat.No: T83804

Synonym: (3’-hydroxy)-PVL,δ-(3’-Hydroxyphenyl)-γ-VL,5-(3’-Hydroxyphenyl)-γ-VL,δ-(3’-Hydroxyphenyl)-γ-Valerolactone

Cat.No: TN3979

Target: PAFR

Cat.No: T82445

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