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77

抑制剂 & 化合物

14

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1509	Casein Kinase Substrates 3
	Casein Kinase Substrates 3 is a substrate of casein kinase.
T2011	RKI1313 RKI 1313,RKI-1313	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	RKI1313 (RKI-1313) 是一种选择性抑制剂，可抑制 ROCK 依赖性信号传导、细胞骨架变化、不依赖锚定的集落形成、迁移和侵袭。
T6941	PI-1840 PI 1840	PARP; Proteasome	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination
	PI-1840 是一种高效的、选择性的蛋白酶体chymotrypsin-like (CT-L)抑制剂，IC50=27nM。
TD0082	EDANS sodium EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-氨乙基氨)-1-萘磺酸钠盐,5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt	Others	Others
	EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) 是开发基于 FRET 的核酸探针的供体，该探针广泛用于实时 PCR 测定。
T11221	ERAP1-IN-1	Others	Others
	ERAP1-in-1 是一种内质网氨基肽酶 1 (ERAP1) 抑制剂，能竞争性地抑制 ERAP1 对代表性生物底物九聚物肽的作用。
T30677L	C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base) C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)	Others	Others
	C15AlkOPP Tetrabutylamine salt 是一种"可点击"的farnesyl diphosphate (FPP)的炔烃修饰类似物。
T6945	Vps34-PIK-III PIK-III,VPS34-IN2	PI3K; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Vps34-PIK-III (VPS34-IN2) 是 VPS34 酶活性的选择性抑制剂，IC50值为18 nM。它可抑制自噬并导致自噬底物稳定。
T30855	CGP77675 CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675	EGFR; VEGFR; Bcr-Abl; Src	Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	CGP77675 (ZINC1488120) 是一种有效的选择性 Src 家族激酶抑制剂，IC50 为 5-20 和 40 nM，用于肽底物的磷酸化和纯化的 Src 的自磷酸化。 CGP77675 具有抗癌活性。
T1757	ML-323 ML323	DUB	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	ML323 是一种有效的可逆的USP1-UAF1抑制剂，在Ub-Rho 测定实验中，IC50为 76 nM。在使用 K63 连接的双泛素 (di-Ub) 和单泛素化 PCNA 的正交凝胶测定中(Ub-PCNA)分别作为底物。
T19139	4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal	Others	Others
	4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) 是 4-硝基苯基 (pNP) 糖吡喃糖苷的人工底物，可用于 α-半乳糖苷酶活性的检测。它用作底物能够显著增加 pNP 的释放量。
T64339	Apcin A HCL	APC	Cell Cycle/Checkpoint
	Apcin A HCL 是 Apcin 衍生物。它是一种后期促进复合物 (APC) 抑制剂。它与 Cdc20 强烈相互作用，并抑制 Cdc20 底物的泛素化。它可用于合成 PROTAC CP5V。
T71602	C1A
	C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.
TD0028	Super Fluor 680, SE
	This Super Fluor 680, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection.
T25855	NC1153 CN-1153,NC-1153,NC 1153,CN 1153,CN1153
	NC1153 is a blocker of IL-2-induced activation of JAK3 and its downstream substrates STAT5a/b. It promotes long-term allograft survival and sparing the recipient from multiple toxicities.
T10345	Apcin-A	Others	Others
	Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.
T41019	Histone H1-derived Peptide Histone H1-derived Peptide
	Histone H1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (CDKs).
T37835	2-Chloro-4-nitrophenyl-α-D-glucopyranoside
	Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate. For example, CNP-β-D-maltoheptaoside and CNP-α-maltotrioside are chromogenic substrates for α-amylase. 2-Chloro-4-nitrophenyl-α-D-glucopyranoside is a conjugate of CNP and α-D-glucose. The related conjugate between CNP and β-D-glucose, 2-chloro-4-nitrophenyl β-D-glucopyranoside, is used as a chromogenic substrate for glycosyltransfera...
T27946	LY-329146 LY 329146
	LY-329146 is a selective estrogen receptor modulator (SERM). LY-329146 prevents doxorubicin resistance in tumor cells expressing multidrug resistance-associated protein (MRP) by inhibiting the binding of MRP substrates to the estrogen receptor.
TD0024	Super Fluor 555, SE
	This Super Fluor 555, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection. Super Fluor 555 dye molecules can be attached to proteins at high molar rat
T39185	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors.
T35976	6-Formylpterin
	Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site, resulting in hetero-substrate" inhibition at nanomolar concentrations. However
T19420	Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate	Others	Others
	Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection. Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative,
TD0030	Super Fluor 750, SE
	This Super Fluor 750, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection.
T70695	CP 100356
	CP 100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. The compound has low uM to nM potency for inhibiting several MDR-1 substrates (calcein-AM, digoxin) in transfected MDCKII cells.
T69701	HS-152
	HS-152 is a novel reversible inhibitor of smurf1, directly targeting the catalytic activity of smurf hect domains, significantly blocking auto-ubiquitination and the transfer of ubiquitin from hect domain to the substrates to form isopeptide bond
T10890	CRTh2 antagonist 3	Others	Others
	CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of 8.4 μM. CRTh2 antagonist 3 has the
TP1580	Activated Protein C (390-404), human TFA
	The peptide region containing residues 390-404 in Activated Protein C (APC) is essential for anticoagulant activity and is available for interaction with antibodies or with other proteins, such as the macromolecular substrates Factors Va or VIIIa. APC reg
T35764	S-Farnesyl Thioacetic Acid
	S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine which behaves as a competitive inhibitor of isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). It can also inhibit methylation of both farnesylated and geranylgeranylated substrates.
TP1903	PKG inhibitor peptide cGMP Dependent Kinase Inhibitor Peptide
	Competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by
T38186	6-Amino-8-trifluoromethylphenanthridine
	6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM. 6A-8tFP directly competes with protein substrates for the ribosomal active site.
T31588	Dynasylan 1161 Y 9138
	Dynasylan 1161 是一种双官能有机硅烷，可以与合适的聚合物反应。在水存在时，Dynasylan 1161可与各种无机基材结合。
T28648	S39625 S-39625,S 39625
	S39625, an E-ring camptothecin keto analogue, is a stable, potent, and selective topoisomerase I inhibitor without being substrates of drug efflux transporters. Nanomolar concentrations of S39625 induces intense and persistent histone gamma-H2AX. The chem
T83799	6-alkyne NAD+ sodium β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD
	6-炔基NAD+是一种可点击的信号分子及酶辅因子NAD+形式。它与荧光标签联用，用于检测聚(ADP-核糖)聚合酶(PARP)蛋白质底物。
T61515	5-HT7 receptor ligand 1
	5-HT7 receptor ligand 1 (Compound 5c) is a potent ligand for the 5-HT7 receptor, with a K i value of 8 nM. The compound demonstrates non-hepatotoxic properties and displays moderate potential for drug-drug interactions with substrates of CYP3A4 or CYP2D6 enzymes [1].
TD0022	Super Fluor 488, SE
	This Super Fluor 488, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection. Super Fluor 488 dye molecules can be attached to proteins at high molar rat
T37901	UDP-N-acetyl-D-Glucosamine (sodium salt hydrate)
	UDP-N-acetyl-D-Glucosamine is a natural nucleotide sugar that is used by glycosyltransferases to transfer N-acetyl-D-glucosamine residues to substrates.1It is an important component of antibiotic biosynthesis pathways in fungi and lipopolysaccharide production in bacteria.2,3 1.Roseman, S.Reflections on glycobiologyJ. Biol. Chem.276(45)41527-41542(2001) 2.Kudo, F., and Eguchi, T.Biosynthetic genes for aminoglycoside antibioticsJ. Antibiot. (Tokyo)62(9)471-481(2009) 3.Mulrooney, E.F., Poon, K.K.,...
T37121	1,2-bis(heptanoylthio) Glycerophosphocholine
	Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH). Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman's reagent) and DTP.
T62810	ZL-Pin13
	ZL-Pin13 是一种高效细胞活性共价抑制剂，选择性作用于 Pin1 (IC50: 67 nM)。ZL-Pin13 能够有效抑制 MDA-MB-231 细胞的增殖，并下调 Pin1 底物。
T75411	beta-1, 3-N-Acetylhexaminyltransferase (LgtA)
	Beta-1, 3-N-Acetylhexaminyltransferase (LgtA) 是一种糖基转移酶，在生化研究中常见。该酶主要催化作用为将 N-乙酰葡糖胺从 UDP-GlcNAc 转移到 N-乙酰乳糖胺和乳糖上。
T76232	Z-DEVD-AMC
	Z-DEVD-AMC 是一种选择性 caspase-3 底物，可通过荧光光谱法测量。 AMC 可用作基于 AMC 的酶底物 (包括基于 AMC 的半胱天冬酶底物) 的荧光参考标准。
T75397	Hyaluronan synthase (PmHAS)
	Hyaluronan synthase (PmHAS)为膜蛋白，依赖Mg+2及两种糖-UDP底物（GlcUA-UDP与GlcNAc-UDP）合成HA链。该酶负责透明质酸(HA)的生物合成。
T76246	NH2-AKK-COOH
	NH2-AKK-COOH，一种合成三肽，是 ACE 抑制剂，当 FAPGG，HHL 和血管紧张素-I 用作底物时的 IC50值分别为 0.090 μM，0.178 μM 和 420.89 μM。
T31200	Dansylmethionine Dansyl methionine,Dansyl-met
	Dansylmethionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the liver. More than 40 methyl transfe
TD0026	Super Fluor 647, SE	Others	Others
	Super Fluor 647, SE 是一种用于标记抗体、肽、蛋白质、示踪物和扩增底物的活性染料，可优化细胞标记和检测。Super Fluor 647, SE 染料分子可以以高摩尔比附着到蛋白质上，而无需显著的自猝灭，从而实现更明亮的共轭和更灵敏的检测。
T75289	NAD sodium
	NAD sodium（β-Nicotinamide Adenine Dinucleotide sodium）为NAD的同类物，能在有机底物氧化反应中被还原为β-烟酰胺腺嘌呤二核苷酸（NADH）。此外，NAD sodium转化成的NADH能传递至线粒体内，间接促进ATP的生成。
T35503	(±)-5,7-Dimethyltocol
	(±)-5,7-Dimethyltocol is a form of tocopherol. It has similar antioxidant activity to α-tocol, but lower activity than γ-tocol, in antioxidant assays using menhaden oil or squalene as substrates. It also increases microviscosity of rat liver liposomes containing phosphatidylcholine (PC) by 70.6% when used at a molar ratio of 0.2 to PC. (±)-Dimethyltocol has been used as an internal standard for the quantification of 5,7-tocol, α- and γ-tocopherol, and α- and γ-tocopheryl quinone by HPLC.
T82617	D-Ala-Lys-AMCA TFA
	D-Ala-Lys-AMCA是一个已知的PEPT1底物，具有发射蓝色荧光的性质。该化合物可被转运至肝癌细胞及Caco-2细胞。D-Ala-Lys-AMCA能够作为工具用于评估PEPT1的特异性底物或其抑制剂。
T75400	N-Acetylhexosamine kinase (NahK)
	N-Acetylhexosamine kinase（NahK）是一种针对葡萄糖型底物的异头激酶，通过催化GlcNAc或GalNAc与ATP在异头C1位置发生磷酸化反应，生成N-乙酰己糖胺1-磷酸（GlcNAc-1P/GalNAc-1P）。
T81576	PA22-2 IKVAV sequence,Laminin A-chain fragment
	PA22-2（IKVAV序列；层粘连蛋白A链片段）为一生物活性肽，源于小鼠层粘连蛋白a1氨基酸2110至2127残基。构成的细胞外基质能够促进神经突生长。
T73610	Lipoprotein lipase
	Lipoprotein lipase 是来自于脂肪组织、心肌和骨骼肌、胰岛和巨噬细胞的多功能酶。Lipoprotein lipase 促进正常脂蛋白代谢、组织特异性底物的输送和利用。Lipoprotein lipase 催化脂质在血液循环的限速步骤。

化合物

Casein Kinase Substrates 3

Cat.No: TP1509

Cat.No: T2011

Synonym: RKI 1313,RKI-1313

Target: ROCK

Cat.No: T6941

Synonym: PI 1840

Target: PARP, Proteasome

Cat.No: TD0082

Synonym: EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-氨乙基氨)-1-萘磺酸钠盐,5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt

Target: Others

Cat.No: T11221

Target: Others

C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)

Cat.No: T30677L

Synonym: C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)

Target: Others

Cat.No: T6945

Synonym: PIK-III,VPS34-IN2

Target: PI3K, Autophagy

Cat.No: T30855

Synonym: CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675

Target: EGFR, VEGFR, Bcr-Abl, Src

Cat.No: T1757

Synonym: ML323

Target: DUB

4-Nitrophenyl α-D-galactopyranoside

Cat.No: T19139

Synonym: PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal

Target: Others

Cat.No: T64339

Target: APC

Cat.No: T71602

Super Fluor 680, SE

Cat.No: TD0028

Cat.No: T25855

Synonym: CN-1153,NC-1153,NC 1153,CN 1153,CN1153

Cat.No: T10345

Target: Others

Histone H1-derived Peptide

Cat.No: T41019

Synonym: Histone H1-derived Peptide

2-Chloro-4-nitrophenyl-α-D-glucopyranoside

Cat.No: T37835

Cat.No: T27946

Synonym: LY 329146

Super Fluor 555, SE

Cat.No: TD0024

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

Cat.No: T39185

Synonym: pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

Cat.No: T35976

Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate

Cat.No: T19420

Target: Others

Super Fluor 750, SE

Cat.No: TD0030

Cat.No: T70695

Cat.No: T69701

CRTh2 antagonist 3

Cat.No: T10890

Target: Others

Activated Protein C (390-404), human TFA

Cat.No: TP1580

S-Farnesyl Thioacetic Acid

Cat.No: T35764

PKG inhibitor peptide

Cat.No: TP1903

Synonym: cGMP Dependent Kinase Inhibitor Peptide

6-Amino-8-trifluoromethylphenanthridine

Cat.No: T38186

Cat.No: T31588

Synonym: Y 9138

Cat.No: T28648

Synonym: S-39625,S 39625

6-alkyne NAD+ sodium

Cat.No: T83799

Synonym: β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD

5-HT7 receptor ligand 1

Cat.No: T61515

Super Fluor 488, SE

Cat.No: TD0022

UDP-N-acetyl-D-Glucosamine (sodium salt hydrate)

Cat.No: T37901

1,2-bis(heptanoylthio) Glycerophosphocholine

Cat.No: T37121

Cat.No: T62810

beta-1, 3-N-Acetylhexaminyltransferase (LgtA)

Cat.No: T75411

Cat.No: T76232

Hyaluronan synthase (PmHAS)

Cat.No: T75397

Cat.No: T76246

Dansylmethionine

Cat.No: T31200

Synonym: Dansyl methionine,Dansyl-met

Super Fluor 647, SE

Cat.No: TD0026

Target: Others

Cat.No: T75289

(±)-5,7-Dimethyltocol

Cat.No: T35503

D-Ala-Lys-AMCA TFA

Cat.No: T82617

N-Acetylhexosamine kinase (NahK)

Cat.No: T75400

Cat.No: T81576

Synonym: IKVAV sequence,Laminin A-chain fragment

Lipoprotein lipase

Cat.No: T73610

Cat. No.	Product Name	Target	Signaling Pathways
T4706	Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐	DNA/RNA Synthesis; Endogenous Metabolite; P2Y Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) 是一种选择性 P2Y6受体激动剂，EC50为300 nM，对人 P2Y6受体的 pEC50为6.52。它可刺激炎症介质的产生、吞噬作用和血管收缩，催化多种底物的葡糖醛酸糖化反应，用于核酸生物合成。
TN6908	Polyporusterone A (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one
	Polyporusterone A 是一种从 P. umbellatus 的子实体中提取出来的三萜羧酸。Polyporusterone A 抑制自由基诱导的红细胞裂解 (溶血) ，可用于研究头发再生和牛皮癣。
T9257	1,3-BUTANEDIOL	Others; Endogenous Metabolite	Metabolism; Others
	1,3-Butanediol 是乙醇二聚体，能够为人体营养提供热量来源，在体内转化为 β-羟基丁酸酯，并具有脑保护和降血糖作用。
TL0009	coniferin Coniferoside,松柏苷,Abietin	Others; Antifungal	Microbiology/Virology; Others
	Coniferin (Abietin) 是一种松柏醇中的葡萄糖苷。它抑制真菌生长和黑化反应，具有 ATP 依赖性转运活性并具有抗氧化作用。
T5693	Pyrroloquinoline quinone disodium salt 吡咯喹啉醌二钠盐,Methoxatin disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt) 一种阴离子型氧化还原循环原醌，作为氧化还原辅助因子。它是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。它是哺乳动物的必需营养素，对免疫功能很重要。
T5283	NADH disodium salt Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠	Others; Endogenous Metabolite	Metabolism; Others
	NADH disodium salt (Disodium NADH) hydrate 是氧化还原酶的辅酶。NADH disodium salt hydrate 在分解代谢过程中起到再生电子供体的作用，包括糖酵解，柠檬酸循环和β-氧化。
T4904	1-Methylguanidine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	1-Methylguanidine hydrochloride 是内源性代谢产物的一种。
T4947	3-Hydroxybutyric acid Butanoic acid,3-羟基丁酸	Endogenous Metabolite	Metabolism
	3-Hydroxybutyric acid (Butanoic acid) 是一种人内源性代谢物，在 I 型糖尿病中升高。它能够调节膜脂的性质。
TN2799	20-Deoxyingenol 3-angelate	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets,
T4415	Katacine	Others	Others
	Katacine 抑制氧气消耗，并抑制电子通过线粒体呼吸链从氧化底物转移到分子氧的速度。 Katacine 是来自蓼科蓼科蓼属的 A 型原花青素聚合物在不同聚合阶段的混合物。 Katacine 是一种抗缺氧药。
T75676	Orotidine 5′-monophosphate trisodium
	Orotidine 5'-monophosphate trisodium 是一种嘧啶核苷酸。Orotidine 5'-monophosphate trisodium 是通过从头合成途径合成的，用于在大量微生物中合成 DNA，包括 M. tuberculosis、S. cerevisiae、S. typhimurium 和 P. falciparum 等等。乳清酸磷酸核糖基转移酶 (OPRT) 以磷酸核糖焦磷酸 (PRPP) 和乳清酸 (OA) 作为底物催化合成 Orotidine 5'-monophosphate trisodium[1]
TN3983	Ergosta-7,22-dien-3-one	NO Synthase; LTR	Immunology/Inflammation
	Ergosta-7,22-dien-3-one 是一种羊毛甾烷，能够从台湾灵芝的子实体中分离得到。Ergosta-7,22-dien-3-one 具有促炎特性，它能刺激一氧化氮的产生，诱导基因的表达，并诱导 J774A.1 细胞产生 TLRs、细胞因子、趋化因子和细胞粘附分子。
TN5414	Wallichinine
	Wallichinine shows inhibitory activity on platelet aggregation caused by platelet activating factor (PAF). Wallichinine with ABCB1 presents valuable clues for the development of novel MDR reversal reagents from natural products, wallichinine can significa
TN1549	Damnacanthal 丹宁卡	IL Receptor; Akt; Syk	Angiogenesis; Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its inhibitory effects on the HGF/c-Met axis.

天然产物

Uridine-5'-diphosphate disodium salt

Cat.No: T4706

Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐

Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor

Polyporusterone A

Cat.No: TN6908

Synonym: (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one

Cat.No: T9257

Target: Others, Endogenous Metabolite

Cat.No: TL0009

Synonym: Coniferoside,松柏苷,Abietin

Target: Others, Antifungal

Pyrroloquinoline quinone disodium salt

Cat.No: T5693

Synonym: 吡咯喹啉醌二钠盐,Methoxatin disodium salt

Target: Others, Endogenous Metabolite

NADH disodium salt

Cat.No: T5283

Synonym: Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠

Target: Others, Endogenous Metabolite

1-Methylguanidine hydrochloride

Cat.No: T4904

Target: Others, Endogenous Metabolite

3-Hydroxybutyric acid

Cat.No: T4947

Synonym: Butanoic acid,3-羟基丁酸

Target: Endogenous Metabolite

20-Deoxyingenol 3-angelate

Cat.No: TN2799

Target: PKC

Cat.No: T4415

Target: Others

Orotidine 5′-monophosphate trisodium

Cat.No: T75676

Ergosta-7,22-dien-3-one

Cat.No: TN3983

Target: NO Synthase, LTR

Cat.No: TN5414

Cat.No: TN1549

Synonym: 丹宁卡

Target: IL Receptor, Akt, Syk

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