56
106
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21543 |
AP 18
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
AP-18 是选择性的 TRPA1 抑制剂。AP-18 可以抑制 50 μM 肉桂醛诱导的 TRPA1 激活,在小鼠和人中的 IC50 分别为 4.5 μM 和 3.1 μM。AP-18 可以逆转 CFA 诱导的小鼠机械性痛觉过敏。AP-18 可以浓度依赖的方式减弱 30 μM AITC 诱导的 Yo-Pro 摄取(IC50= 10.3 μM)。 | |||
T23344 |
SDZ 220-040
SDZ-220-040 |
NMDAR | Neuroscience |
SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂,可诱导根系生长的部分无重力模式 。 | |||
T83983 |
WAY-239196
|
Others | Others |
WAY-239196 调节植物植物生长调节活性,抑制油菜幼苗的根系生长。 | |||
T24897 |
TP0427736
TP427736,TP-0427736,TP-427736 |
TGF-beta/Smad | Stem Cells |
TP0427736 是一种有效的选择性 ALK5 抑制剂,IC50 为 2.72 nM,比对 ALK3 的抑制作用高 300 倍。 TP0427736 可降低人外根鞘细胞中 TGF-β 诱导的生长抑制,并延长小鼠毛囊中的生长期。 | |||
T0992 |
Carbenoxolone disodium
Biogastrone,Duogastrone,甘珀酸钠,Bioral |
Gap Junction Protein | Cytoskeletal Signaling |
Carbenoxolone disodium (Duogastrone) 是甘草酸的活性代谢物和人11β-HSD 和细菌3α, 20β-HSD 的抑制剂。它是一种缝隙连接的解耦剂,可抑制牛痘病毒生长,用于消化性、食道和口腔溃疡和炎症的相关研究。 | |||
T9625 |
Sandalore
|
Apoptosis | Apoptosis |
Sandalore 通过减少细胞凋亡和增加外根鞘中延长生长期的生长因子 IGF-1 的产生来延长人类头发的生长。 Sandalore 是嗅觉受体 OR2AT4 的选择性激动剂。 | |||
T64368 |
ES9-17
|
Others | Others |
ES9-17 是网格蛋白介导的内吞作用 (CME)的抑制剂。 CME 是植物胞外环境中质膜蛋白和分子内化的主要途径。ES9-17 抑制FM4-64和转铁蛋白的摄取。ES9-17 可以抑制拟南芥 (Arabidopsis) 幼苗的根生长。 | |||
T9495 |
Haloxyfop methyl ester
|
Others | Others |
Haloxyfop methyl ester 是一种选择性除草剂,脂肪酸合成抑制剂,具有内吸作用。茎叶经处理后,迅速被杂草吸收并传递至全株,水解成酸,抑制根、茎分生组织的生长,导致死亡。 | |||
T37739 |
N-decanoyl-L-Homoserine lactone
C10-HSL,N-decanoyl-L-Homoserine lactone |
Reactive Oxygen Species; Antibacterial | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高,增加丝裂原激活蛋白激酶 6 (MPK6) 的活性,并促使一氧化氮 (NO) 的产生。 | |||
T32747 |
Licorice saponin C2
Saponin C2, from licorice,Licoricesaponin C2 |
||
Licorice saponin C2 is an oleanane-type triterpene oligoglycoside extracted from the air-dried root of Glycyrrhiza uralensis. | |||
T32642 |
Lepetine
|
||
Lepetine is an alkaloid extracted from the root of Aconitum psedohuiliense. | |||
T34517 |
Sapriparaquinone
|
||
Sapriparaquinone is a diterpenoid quinone that is isolated from the root of Salvia prionitis Hance. | |||
T17163 |
Trifluralin
|
Others | Others |
Trifluralin is a commonly used pre-emergence herbicide. It inhibits root development by interrupting mitosis and thus can control weeds as they germinate. | |||
T69459 |
Cistifolin
|
||
Cistifolin is an integrin-dependent cell adhesion blocker from the anti-rheumatic herbal drug, gravel root | |||
T33650 |
Netzahualcoyondiol
|
||
Netzahualcoyondiol 是一种三萜类天然产物,可以从 Cheiloclinium cognatum 的根皮分离得到。 | |||
T32641 |
Lepenine
|
||
Lepenine is an alkaloid extracted from the root of Aconitum psedohuiliense. | |||
T34437 | Rubiatriol | ||
Rubiatriol is a triterpenoid isolated from the root of Rubia cordifolia L. | |||
T20781 |
Maleic hydrazide
Antergon,Antyrost,Hydrazide maleique,Burtolin,抑芽丹 |
||
Maleic hydrazide, a herbicide, inhibits the sprouting in vegetables and stored root crops, prevents sucker production in tobacco plants, controls the growth of foliage, and grass. | |||
T25852 |
Naxillin
|
||
Naxillin is the first non-auxin-like molecule that promotes root branching which acts as a specific lateral root development modulator. | |||
T32640 | Lepedine | ||
Lepedine is a diterpenoid alkaloid extracted from the root of Aconitum psedohuiliense. | |||
T25110 |
AS1069562
AS-1069562,AS 1069562 |
||
AS1069562 is an inhibitor of serotonin (5-HT) and norepinephrine (NE) reuptake which acts by notably restoring reduced insulin-like growth factor 1 and fibroblast growth factor 2 mRNA levels in dorsal root ganglion and spinal cord, respectively. | |||
T30704 |
Capaurine
NSC 404532,NSC-404532,(-)-Capaurine,NSC404532 |
||
Capaurine is an alkaloid extracted from root tubers of Stephania kwangsiensis H.S. Lo. | |||
T4550L |
Ajmaline hydrochloride
|
||
Ajmaline hydrochloride is an alkaloid found in the root of Rauwolfia serpentina, and other plant sources. It is a class of Ia antiarrhythmic agent that apparently works by changing the shape and threshold of cardiac action potentials. | |||
TP1934 |
L-R4W2
|
||
Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo. | |||
T37296 |
GI-530159
|
||
TREK1 and TREK2 channel activator (EC50 = 0.76 μM in Rb efflux assay in TREK1-expressing CHO cells). Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane potential of dorsal root ganglion neurons and depresses neuronal activity in vitro. Loucif et al (2018) GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P) channel opener, reduces rat dorsal root ganglion neuron excitability. Br.J.Pharmacol. 175 2272 PMID... | |||
T61081 |
DFPM
|
||
DFPM, a chemical compound, acts as an activator of the plant resistance protein signaling in roots, thereby causing inhibition of root growth. It also reduces the viability of root cells specifically in the Col-0 accession. Notably, DFPM displays sensitivity to light when dissolved in aqueous solutions. It acquires bioactivity through light-induced and oxygen-dependent modification [1]. | |||
T24814 |
Sortin2
Sortin-2,Sortin 2 |
||
Sortin2 is a sorting inhibitor that acts upstream from the morphological marker of lateral root primordium formation, the mitotic activity. | |||
T19754 | Cetrimide | ||
Cetrimide is an antiseptic. It is used to irrigate root canals to ensure the disinfection and removal of microbial residues. | |||
TP2070 |
BDS I
|
||
Potent and reversible Kv3.4 potassium channel blocker (IC50 = 47 nM); also attenuates inactivation of sodium currents by acting on Nav1.7 and Nav1.3 channels. Enhances TTX-sensitive sodium currents in rat small dorsal root ganglion neurons. Neuroprotective. | |||
T33401 |
Missourin
|
||
Missouri is a triterpenoid derived from the root of the Missouri iris. In addition, two known triterpenes, iso-iridogermanal, and zeorin, were isolated and identified. | |||
T37086 |
PDDHV
|
||
PDDHV is a resiniferatoxin-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat transient receptor potential cation channel subfamily V member 1 (TRPV1), formerly known as vanilloid receptor 1. It induces Ca2+-uptake by rat dorsal root ganglion neurons with an EC50 value of 70 nM. | |||
T21094 |
Pseudopelletierine free base
NSC 116056,Granatonine,Pseudopelletierine,Granatan-3-one |
||
Pseudopelletierine is the main alkaloid derived from the root-bark of Punica granatum, along with at least three other alkaloids: isopelletierine, methylpelleteirine (C9H17ON) and pelletierine, which yield 1.8, 0.01, 0.20 and 0.52 grams per kilogram of ra | |||
T83007 |
Antitumor agent-120
|
||
Antitumor agent-120 (compound 1) 为一类黄酮化合物,来源于葛根提取。本化合物对LNCaP和PC3癌细胞的抑制作用不明显,表现出IC50s均大于50 μM。 | |||
T80428 |
Jingzhaotoxin-34
|
Sodium Channel | Membrane transporter/Ion channel |
Jingzhaotoxin-34是一种含35个氨基酸残基的多肽神经毒素,能特异性抑制TTX-S钠电流(IC50约85 nM),对大鼠背根神经节TTX-R钠电流无显著作用。 | |||
T16135 |
MRS 1523
|
Others | Others |
MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 receptor antagonist Ki: 18.9 nM and 113 n | |||
T81970 |
Kuwanon T
|
||
Kuwanon T为一种源自桑树根皮的异戊二烯黄酮类化合物,能抵御t-BHP诱导的氧化应激,其EC50值为30.32 μM。 | |||
T78643 |
Penflufen
|
||
Penflufen是一种效率高、谱面广的琥珀酸脱氢酶(SDH)抑制剂,可作为杀菌剂针对多种真菌病害提供广泛的生物活性,涉及作物疾病包括但不限于马铃薯黑皮病、小麦尖眼斑病、水稻纹枯病及花生根腐病等。 | |||
T14218 |
Amicarbazone
BAY314666,胺唑草酮,BAY-MKH 3586 |
Others | Others |
Amicarbazone (BAY-MKH3586; BAY314666) is a potent PSII inhibitor, disrupting photosynthetic electron transport by binding to the Qb domain of photosystem II. This broad-spectrum herbicide is effective through foliar and root application, showcasing rapid absorption and translocation. However, its effectiveness can be compromised by common PSII inhibitor resistance. With an IC50 value indicating high potency, amicarbazone leads to chlorosis, stunted growth, tissue necrosis, and death in sensitive... | |||
T79246 |
6-Iodoamiloride
|
Sodium Channel | Membrane transporter/Ion channel |
6-Iodoamiloride作为一种有效的酸敏感离子通道1(ASIC1)抑制剂,其IC50值为88 nM。同时,该化合物能够抑制大鼠背根神经节神经元中ASIC3介导的电流,其IC50值为230 nM。 | |||
T80186 |
Hainantoxin-III
|
Sodium Channel | Membrane transporter/Ion channel |
Jingzhaotoxin-V是一种多肽,具有抑制作用,IC50值为604.2 nM,可显著抑制非洲爪蟾卵母细胞的钾电流。此外,Jingzhaotoxin-V对大鼠背根神经节神经元中的河豚毒素抗性钠电流和河豚毒素敏感钠电流也有抑制效果,其IC50值分别为27.6 nM和30.2 nM[1]。 | |||
T80421 |
CSD-CH2(1,8)-NH2
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
CSD-CH2(1,8)-NH2 是一种针对KOR的选择性且竞争性拮抗剂,具有较低的Ki值(6.8 nM),能够抑制DRG神经元内的钙动员,并能拮抗U50,488的抗伤害效应,常用于神经精神疾病研究领域。 | |||
T35699 |
Fosetyl-aluminum
|
||
0 [1]. Fan Z, Jia S, Ding N, et al. Determination of Fosetyl-Aluminium by Ion-Pair Reversed Phase-High Performance Liquid Chromatography With Evaporative Light Scattering Detection. Se Pu. 2009;27(6):849‐851. [2]. TüRK LMEZ , et al. Activity of metalaxyl-M+mancozeb, fosetyl-Al, and phosphorous acid against Phytophthora crown and root rot of apricot and cherry caused by Phytophthora palmivora. Plant Protect. Sci., 53: 216-225. | |||
T80455 |
ω-Conotoxin CVIB
|
Sodium Channel | Membrane transporter/Ion channel |
ω-Conotoxin CVIB为非选择性N型及P/Q型电压门控钙通道(VGCC)拮抗剂,能够抑制背根神经节(DRG)中神经元去极化后激活全细胞VGCC电流,其pIC50值为7.64。 | |||
T82019 |
JA-ACC
Jasmonyl-ACC |
||
JA-ACC(Jasmonyl-ACC)是1-氨基环丙烷-1-羧酸(ACC)衍生物,后者是植物激素乙烯的直接前体。JA-ACC可抑制Arabidopsis根生长,此作用与茉莉酸(JA)信号通路无关。 | |||
T80495 |
mHuwentoxin-IV
|
Sodium Channel | Membrane transporter/Ion channel |
mHuwentoxin-IV是一种经天然修饰的Huwentoxin-IV。该化合物针对背根神经节中河豚毒素敏感(TTX-S)电压门控钠通道(sodium channels)表现出抑制作用,IC50值为54.16 nM。mHuwentoxin-IV对这些钠通道的抑制作用并不会因强去极化电压而逆转。 | |||
T37201 |
CAY10787
|
||
CAY10787 is an oxysterol and a negative allosteric modulator of GABAAreceptors.1,2It reduces GABA-induced currents in HEK cells expressing α1β1γ2or α4β3γ2subunit-containing GABAAreceptors (IC50s = 1.5 and 1 μM, respectively).2CAY10787 (500 nM) reduces GABA-induced depolarization of peptidergic and non-peptidergic nociceptors, C-LTMRs, and cold thermosensors in isolated mouse dorsal root ganglion (DRG) neurons.In vivo, CAY10787 (2, 10, and 50 mg/kg) increases latency to nocifensive behaviors in t... | |||
T80425 |
Jingzhaotoxin-V
|
Sodium Channel | Membrane transporter/Ion channel |
Jingzhaotoxin-V是Chilobrachys jingzhao蜘蛛毒液中的一种含29个氨基酸残基的多肽。该化合物抑制大鼠背根神经节神经元的河豚毒素抗性和河豚毒素敏感sodium currents,相应IC50值为27.6 nM与30.2 nM。同时,Jingzhaotoxin-V也能抑制表达在爪蟾卵母细胞中的Kv4.2钾电流,IC50值为604.2 nM。 | |||
T80066 |
ShK toxin
|
Potassium Channel | Membrane transporter/Ion channel |
ShK toxin 是从加勒比海葵(Stichodactylu helianthus)的全身提取物中分离出的一种蛋白,能够阻断电压依赖性钾通道(Kv1.3 通道)。在竞争实验中,ShK toxin 与树突毒素 I 及α-树突毒素相互竞争,以与大鼠脑突触体膜结合,从而促进乙酰胆碱的释放。此外,ShK toxin 抑制培养的大鼠背根神经节神经元中的K+ 电流,并且能够抑制T淋巴细胞的增殖。 | |||
T83701 |
TRPV1-Tat TFA
Transient Receptor Potential Vanilloid 1-Tat,736-745-Tat |
||
TRPV1-Tat是一种针对瞬时受体电位范烤苷1 (TRPV1) 的肽类拮抗剂。它由来自TRPV1的A-激酶锚蛋白(AKAP)结合域的736-745个氨基酸以及来自HIV Tat的细胞穿透肽序列组成。TRPV1-Tat (200 µM) 能够在使用初级小鼠背根神经节的整细胞膜片钳技术中抑制由热或棕榈酸酯12-肉豆蔻酸13-醋酸酯(PMA014)引起的电流。当以10或30 µM剂量给药时,它能增加大鼠后爪机械痛阈。 | |||
T83728 |
Tat-AKAP79 (326-336) TFA
Tat-A-kinase Anchor Protein 79 (326-336) |
||
Tat-AKAP79 (326-336) 是一种肽,由HIV-1 Tat蛋白质转导域与对应于A-kinase anchor protein 79 (AKAP79) 326至336残基的11个氨基酸肽链相连组成。在200 µM浓度下,能抑制蛋白激酶A (PKA) 或PKC激活诱导的瞬时受体电位钒通道1 (TRPV1) 在分离的大鼠背根神经节 (DRG) 神经元中的敏感化。在体内,Tat-AKAP79 (326-336) 抑制小鼠由甲醛或phorbol 12-myristate 13-acetate (PMA014) 引发的伤害性行为。它还延长了小鼠对辐射热刺激爪子撤回的潜伏期,并在卡拉胶诱导的炎症性疼痛小鼠模型中增加了爪子撤回的机械阈力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21164 |
Sulfentrazone
甲磺草胺,FP-846 |
Others | Others |
Sulfentrazone (FP-846) 是苯基三唑啉酮除草剂,能够抑制原卟啉原氧化酶,导致脂质细胞膜破裂,可用于控制某些阔叶和禾本科杂草。 | |||
T8283 |
(+)-Bornyl Acetate
Bornyl acetate,1-乙酸冰片酯,(+)-乙酸龙脑酯 |
Others | Others |
(+)-Bornyl Acetate 存在于 Pichtae 精油 (西伯利亚冷杉针油) 中。它能够显著抑制拟南芥幼苗根系生长。 | |||
T12581 |
Puerarin-4'-O-β-D-glucopyranoside
Puerarin4'-O-glucoside,葛根素-4'-Β-D-葡萄糖苷 |
Others | Others |
Puerarin-4'-O-β-D-glucopyranoside (Puerarin4'-O-glucoside) 是一种从葛根 (PLR) 中提取的异黄酮。它具有雌激素活性和抗 MCF-7 人乳腺癌细胞增殖作用。 | |||
TN3008 |
4',4''-Dihydroxyanigorootin
|
Others | Others |
4',4''-Dihydroxyanigorootin is a natural product from Musa cv."Thepanom" (BBB). | |||
TN7066 |
Coryneine
2-(3,4-dihydroxyphenyl)ethyl-trimethylazanium,Quaternary dopamine,Trimethyl(3,4-dihydroxyphenethyl)aminium,棍掌碱,Dopamine methiodide |
Others | Others |
Coryneine (Trimethyl(3,4-dihydroxyphenethyl)aminium) 是从附子根中提取的多巴胺的季铵衍生物。 | |||
T2S2150 |
Noricaritin
诺里卡汀,去甲淫羊藿黄素 |
Others | Others |
Noricaritin 是一种来源于淫羊藿根的黄酮类化合物。 | |||
TMA0835 |
Deapi-platycodin D3
去芹糖桔梗皂苷D3,去芹-桔梗皂苷D3 |
Others | Others |
Deapi-platycodin D3 是一种三萜皂苷,从桔梗根中提取得到。 | |||
T75675 |
Nepasaikosaponin K
|
Antiviral | Immunology/Inflammation |
Nepasaikosaponin K 是一种从柴胡根中分离出来小分子化合物,具有抗流感和抗病毒活性,可用于研究病毒感染。 | |||
T2984 |
Scopoletin
Chrysatropic acid,东莨菪内酯,Esculetin 6-methyl ether,Gelseminic acid,6-Methylesculetin |
Apoptosis; AChR; AChE | Apoptosis; Neuroscience |
Scopoletin (Esculetin 6-methyl ether) 是一种源自东莨菪根的植物生长因子,可抑制乙酰胆碱酯酶。 | |||
T3149 |
Salvianolic Acid C
丹酚酸C,丹酚酸 C |
Others; P450 | Metabolism; Others |
Salvianolic acid C 是一种细胞色素 P4502C8(CYP2C8)的非竞争性抑制剂及细胞色素 P4502J2(CYP2J2)中等强度的混合抑制剂,对 CYP2C8 和 CYP2J2 的 Ki 分别为 4.82 μM 和 5.75 μM。 | |||
T0724 |
Formononetin
Biochanin B,Flavosil,刺芒柄花素,Formononetol |
Apoptosis; FGFR | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
Formononetin (Flavosil) 是一种 FGFR2抑制剂,IC50约为4.31 μM。 它是一种 O-甲基化的异黄酮,是来自黄芪根的植物雌激素,可有效抑制血管生成和肿瘤生长。 | |||
T6S1500 |
Ginsenoside Rf
人参皂苷 Rf,Ginsenoside-Rf,Panaxoside Rf |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
Ginsenoside Rf (Panaxoside Rf) 是人参根的微量成分,可抑制 N 型 Ca2+通道。 | |||
T5S1645 |
Apiopaeonoside
丹皮酚新苷 |
Others | Others |
Apiopaeonoside 是一种天然产物,分离自Paeonia suffruticosa 根部。 | |||
TN6723 |
Lactiflorin
|
Others | Others |
Lactiflorin 是一种具有肾脏保护作用的单萜苷。 | |||
TN6797 |
Isoneochamaejasmin A
|
Others | Others |
Isoneochamaejasmin A 是一种双黄酮类化合物,是一种广泛使用的中药 stellera chamaejasme L. 干燥根中的主要活性成分之一。 | |||
T5S0733 |
Picroside III
|
Others | Others |
Picroside III(胡黄连苷 III)是一种环烯醚萜苷,分离自传统中药胡黄连中。 | |||
T40807 |
1,3-Dimethylpyrazole
1,3-Dimethyl-1H-pyrazole,2,5-Dimethylpyrazole |
Others | Others |
1,3-Dimethylpyrazole (2,5-Dimethylpyrazole) 是一种存在于毛竹根的生物活性物质。 | |||
T2757 |
Myricitrin
杨梅苷,Myricetrin,Myricitrine |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Myricitrin (Myricitrine) 是从杨梅根皮中分离出来的类黄酮化合物,具有镇痛作用。它是主要的抗氧化剂。 | |||
T67922 |
Lepidiline C
|
Others | Others |
Lepidiline C 是一种 从十字花科Lepidium meenii Walpers 根中提取的新型的咪唑类生物碱 ,对HL-60细胞表现出细胞毒活性(IC50为:27.7 μM)。 | |||
TN6795 |
5-Methoxysuberenone
|
Others | Others |
5-Methoxysuberenone 是 Toddalia asiatica (L.) Lam 根皮的化学成分。 (T. aculeata Pers.),芸香科。 | |||
T4S0675 |
Polygalasaponin V
瓜子金皂苷V,瓜子金皂苷 V |
Others | Others |
Polygalasaponin V 是一种三萜皂苷,分离自Polygala japonica 的地上部分。其中Polygala japonica 是民间的药用植物,在中国南方用作祛痰、抗菌、抗炎、抗抑郁药。 | |||
T3873 |
griffonilide
|
Others | Others |
Griffonilide 是一种提取自Semiaquilegia adoxoides 根中的丁烯内酯类化合物,常与紫草甙一起出现。它是一种传统抗癌药草。 | |||
TN7103 |
13,21-Dihydroeurycomanone
Pasakbumin C |
Anti-infection; Parasite | Microbiology/Virology |
13,21-Dihydroeurycomanone (Pasakbumin C) 是从 Eurycoma longifolia 根部分离得到的一种天然产物,有抗寄生虫活性。 | |||
T12500 |
Platycoside E
Platycodin E,桔梗苷E |
Others | Others |
Platycoside E (Platycodin E) 是一种桔梗皂苷元型皂苷,从桔梗的根中分离获得,能够促进 ovalbumin 免疫小鼠中血清 OVA 特异性IgG2a 和IgG2b 抗体的产生。它具有溶血活性和佐剂潜力。 | |||
T0522 |
Diammonium Glycyrrhizinate
甘草酸二铵,Glycyrrhizin |
Dehydrogenase | Metabolism |
Diammonium Glycyrrhizinate (Glycyrrhizin) 是分离自甘草中的化合物,有抗炎作用。 | |||
T8859 |
NITIDINE
|
Others | Others |
NITIDINE 是一种从花椒根中分离出来的具有生物活性的植物苯并菲啶生物碱。它具有抗癌、神经保护、抗疟疾、抗 HIV、镇痛、抗炎和抗真菌活性。 | |||
T0725 |
Isoliquiritigenin
异甘草素,ISL,Isoliquiritigen,GU17 |
Apoptosis; Influenza Virus; Reductase; Autophagy | Apoptosis; Autophagy; Endocrinology/Hormones; Metabolism; Microbiology/Virology |
Isoliquiritigenin (ISL) 是从光果甘草根中分离得到的一种黄酮类天然产物,具有抗肿瘤的活性。它抑制流感病毒复制,EC50为 24.7 μM,还能抑制 aldose reductase 的活性,IC50值为 320 nM。 | |||
T3150 |
Caudatin
告达亭苷元,告达庭 |
Apoptosis; Others | Apoptosis; Others |
Caudatin 是白首乌中的一种甾体类天然产物,具有抗肿瘤和抗血管生成作用。它是一种 C-21 甾体糖苷,可使细胞周期停滞,诱导细胞凋亡。 | |||
T20945 |
2,4-D
Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。 | |||
T4953 |
Neotuberostemonine
|
NOS | Immunology/Inflammation |
Neotuberostemonine 是一种结核分枝杆菌根中主要的止咳生物碱,能够阻碍巨噬细胞的募集和活化,从而减轻博来霉素 (Bleomycin) 诱导的肺纤维化。 | |||
TMS2182 |
trans-Zeatinriboside
Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷 |
Others | Others |
trans-Zeatinriboside (Ribosylzeatin) 是一种细胞分裂素前体,是木质素导管中主要的长距离信号形式,能够调节叶片大小和分生组织活性相关形状。 | |||
T2230 |
Paeoniflorin
芍药苷,Peoniflorin |
HSP; COX | Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; Neuroscience |
Paeoniflorin (Peoniflorin) 是从芍药根中提取的一种蒎烷单萜糖苷,具有抗癌作用、抗氧化应激、抗血小板聚集、血管扩张、降低血液粘度和抗炎活性等多种生物活性。它是一种热休克蛋白诱导剂,通过自噬途径保护 PC12 细胞免受 MPP+和酸性损伤。 | |||
Fr13883 |
3-Methoxyphenylacetic acid
|
Others | Others |
3-Methoxyphenylacetic acid 是 m-hydroxyphenylacetic (m-OHPAA) 的衍生物,茄形假丝酵母中的一种植物毒素。它可用于针对介氧菌根腐烂的毒素介导的生物测定法的开发。 | |||
T2996 |
Tetrandrine
NSC-77037,d-Tetrandrine,Hanfangchin A,粉防己碱,Fanchinine,Sinomenine A,汉防己甲素 |
Potassium Channel; Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Tetrandrine (Sinomenine A) 是来自粉防己的一种双苯基异喹啉生物碱,可抑制电压门控钙离子通道 (ICa) 和 Ca2+激活的钾离子通道。 | |||
TN3861 |
Dihydropinosylvin
山药 |
Anti-infection | Microbiology/Virology |
Dihydropinosylvin 是一种植物抗毒素,对枝孢枝孢菌、Botryodiplodia theobromae、黑曲霉和石化青霉具有抗真菌活性,对蜡状芽孢杆菌、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌也有很强的抗菌活性。双色高粱幼苗的种子和根伸长。 | |||
T5088 |
3-Indoleacetic acid sodium
Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,吲哚乙酸钠,Heteroauxin sodium salt |
Others; Endogenous Metabolite | Metabolism; Others |
3-Indoleacetic acid sodium (Heteroauxin sodium salt) 是一种天然存在的植物生长素类激素。能刺激细胞伸长和分裂,促进植物生长发育。然而,高浓度时,它表现出生长抑制作用,包括生长和阻止茎和根的生长。后一种效应形成了合成生长素被开发为农业除草剂和生物调节剂的基础。 | |||
T6S0735 |
Flavokawain B
黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone |
Apoptosis; Others | Apoptosis; Others |
Flavokawain B (Flavokavain B) 是从卡瓦醉椒的根提取物中,分离出的查尔酮。它是一种凋亡诱导剂,可抑制各种癌细胞株生长。它以极低的无毒浓度抑制人脑内皮细胞的迁移和血管形成,具有抗血管生成活性。 | |||
TMM2618 |
Gibberllin A7
Gibberellin A7,Gibberllin 7,赤霉素GA7 |
Others | Others |
Gibberllin A7 (Gibberllin 7) 是重要的植物生长激素,可促进植物细胞生长和伸长。它可促进茎和根的快速生长,诱导有丝分裂并启动(打破休眠)并提高种子发芽率。它还参与诸如作为向地力、张力和花卉展示。Gibberellin A3(G1025, G7645) 和 A4 (G7276) 可用作植物生长培养基如 Murashige 和 Skoog 培养基的补充剂。 A3 和 A4 或 Gebberellins 组合的具体作用应在具体的植物应用中确定。 | |||
T32745 |
Liconeolignan
|
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Liconeolignan is extracted from the root of Glycyrrhiza uralensis. | |||
T30170 |
Aspafilioside A
|
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Aspafilioside A is a steroidal saponin isolated from the root of Asparagus filicinus. | |||
TN6480 |
Benzoylmesaconine hydrochloride
|
||
Benzoylmesaconine hydrochloride has used as the reference standard to evaluate the quality of processed aconite root and powdered processed aconite root. | |||
TN4718 |
Orobanchyl acetate
|
Others | Others |
Orobanchyl acetate is a germination stimulant for root parasitic plants. | |||
T25653 |
Leiocarpaquinone
|
||
Leiocarpaquinone is a bioactive chemical from root of Uentilago leiocarpa Benth. (Rhamnaceae). | |||
TN2338 |
Guanfu base G
Guan-fu base G,关附庚素 |
Others | Others |
Guan-fu base G is derived from the tuberous root of the Aconitum aurantium plant. | |||
T13654 |
DL-m-Tyrosine
|
Others | Others |
DL-m-Tyrosine shows effects on Arabidopsis root growth. | |||
T13885 |
Siraitic Acid A
|
Others | Others |
Siraitic Acid A is a natural product(cucurbitane triterpenoid) isolated from the root of S. grosvenori . | |||
T29794 |
Akagerine
|
||
Akagerine is derived from the root bark of South American Strychnos. | |||
TN4249 |
Ilicol
|
Others | Others |
Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. They reduce Allium cepa cell | |||
T82634 |
Cynatratoside D
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Cynatratoside D为从白黎芦醇根部分离提取的一种寡糖苷。 | |||
T83112 |
Angulatin B
|
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Angulatin B,一种天然产物,存在于Celastrus angulatus根皮中。 | |||
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