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61

抑制剂 & 化合物

9

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38219 11-cis Retinal

11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low vi...
T39280 Nitrofen

Others Others
Nitrofen 是选择性接触除草剂,也是视原卟啉原氧化酶和网膜脱氢酶抑制剂。
T2055 WS3

EGFR; IκB/IKK Angiogenesis; JAK/STAT signaling; NF-κB; Tyrosine Kinase/Adaptors
WS3 是一种可促进鼠和人原代胰岛的胰腺 β 细胞增殖的增殖分子。它可用于研究 I 型糖尿病。
T2026 CYM5442

S1P Receptor; LPL Receptor GPCR/G Protein
CYM5442 是高选择性和口服活性的鞘氨醇 1-磷酸受体激动剂,EC50为 1.35 nM。它激活依赖 S1P1的 p42/p44-MAPK 磷酸化,具有视网膜神经保护作用,可轻松穿过中枢神经系统。
T21807 INCA-6

Triptycene-1,4-quinone

Others Others
INCA-6 (Triptycene-1,4-quinone) 是细胞渗透性的 NFAT 抑制剂。INCA-6 通过特异性阻断 NFAT 底物靶向钙调神经磷酸酶位点,有效抑制calcineurin (CN)-NFAT 信号传导。
T5194 SPHINX31

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
SPHINX31 是丝氨酸/富含精氨酸的蛋白激酶1的选择性抑制剂,其IC50值为 5.9 nM。它有效抑制丝氨酸/丰富精氨酸的剪接因子1 磷酸化,有用于局部新生血管性眼病的研究潜力。
T34299 Retinaloxime

trans-Retinaloxime

Retinaloxime is a retinoid.
T29395 3-Diazirinophenylretinal

3-Diazirinophenylretinal is a bioactive chemical.
T5913 Sulbutiamine

舒布硫胺,Bisibuthiamine

Antioxidant oxidation-reduction
Sulbutiamine (Bisibuthiamine) 是合成的维生素 B1 类似物,可用于研究无力症。
T62858 hGPR91 antagonist 3

GPR Endocrinology/Hormones; GPCR/G Protein
hGPR91 antagonist 3 是一种具有口服活性、有效性和选择性的 hGPR91 拮抗剂。hGPR91 antagonist 3 可用于研究高血压、自身免疫性疾病和视网膜血管生成方面的疾病。
T25829 Mopidamol

RA233,RA 233,RA-233,Rapenton,OLX 102

PDE Metabolism
Mopidamol (RA 233) 是一种磷酸二酯酶抑制剂,是 dipyridamole 衍生物,具有抗癌活性,可预防实验性糖尿病的视网膜血管缺陷。
T30480 BiP inducer X

BIX

Apoptosis Apoptosis
BiP inducer X (BIX) 是免疫球蛋白重链结合蛋白 (BiP)/GRP78 的选择性诱导剂和 ER 伴侣诱导剂。 BiP inducer X 可防止神经元和视网膜细胞系中的细胞死亡。
T22282 Brr2-IN-3

Brr2 Inhibitor 9,Brr2 Inhibitor C9

Others Others
Brr2-IN-3 (Brr2 Inhibitor C9) 是选择性 Brr2解旋酶变构抑制剂。它呈剂量依赖性地抑制解旋酶(IC50:1.3 μM)。
T72662 NMDAR/TRPM4-IN-2

ERK; TRP/TRPV Channel; NMDAR; iGluR MAPK; Membrane transporter/Ion channel; Neuroscience
NMDAR/TRPM4-IN-2 是一种有效的 NMDAR/TRPM4 相互作用界面抑制剂。NMDAR/TRPM4-IN-2 保护小鼠免受 MCAO 诱导的脑损伤和 NMDA 诱导的视网膜神经节细胞丢失。NMDAR/TRPM4-IN-2 具有神经保护活性, 可预防 NMDA 诱导的海马神经元细胞死亡和线粒体功能障碍,其 IC50 值为 2.1 μM。
T37081 HIOC

Selective TrkB receptor agonist. Protects neurons from excitotoxicity. Protects retinas from light-induced retinal degeneration (LIRD) in vivo. Blood brain barrier and blood-retinal barrier penetrant.
T13524 9-cis-β-Carotene

Others Others
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo.
T70329 SH-11037

SH-11037 is a novel potent seh inhibitor, effectively blocking key angiogenic properties of human retinal endothelial cells (hrecs), inhibiting choroidal sprouting and significantly suppressing cnv lesion volume
TP2393 Neurotensin-related hexapeptide

Lant-6

Neurotensin-related hexapeptide exists in retinal ganglion cells and in their central projections in pigeons and may be utilized as a neuroactive substance by the central terminals of numerous retinal ganglion cells in birds.
T29809 AL-1

AL 1,AL1

AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variety of adult tissues of BRAIN; HEART;
T81341 Pyr-Gly

Pyr-Gly为抑制肽类化合物,能够抑制视网膜色素上皮(RPE)细胞及成纤维细胞的增殖作用。
T71715 CU239

CU239 is a selective non-retinoid inhibitor of RPE65 which suppresses visual cycle and prevents retinal degeneration.
T71488 Cremastranone

Cremastranone is a natural antiangiogenic homoisoflavanone. Cremastranone inhibits the proliferation, migration, and tube formation ability of human retinal microvascular endothelial cells.
T76574 Arginyl-Glutamine

Arginyl-Glutamine 是一种二肽,可以降低VEGF 水平,并抑制氧诱导视网膜病变小鼠模型中的视网膜新生血管。
T28487 Quininib

Quininib is a regulator of Ocular Angiogenesis. Quininib significantly inhibits angiogenic tubule formation in HMEC-1 cells, angiogenic sprouting in aortic ring explants and retinal revascularisation in OIR mice.
T78404 Pyridinium bisretinoid A2E TFA

A2E TFA

Apoptosis Apoptosis
Pyridinium bisretinoid A2E TFA作为一种荧光团,能从视网膜色素上皮(RPE)的脂褐素中分离得到,是蓝光诱导的细胞凋亡(apoptosis)诱导剂。该化合物具有光活化特性,可介导自噬(autophagy)和活性氧(reactive oxygen species)的产生,常用于视网膜退行性疾病的研究。
T69972 ONL-1204

ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.
T73476 YC-001

YC-001 是一种针对杆状视蛋白的反向激动剂和拮抗剂。它能与视杆视蛋白可逆地结合,从而稳定其结构,保护小鼠免受强光诱导的视网膜变性,显示出研究视网膜变性疾病潜力。
T36617 ent-8-iso Prostaglandin F2α

ent-8-iso Prostaglandin F2α

ent-8-iso Prostaglandin F2α 是猪视网膜和脑微血管的强效血管收缩剂,EC50 值分别为 30.6 和 53.5 nM。
T40680 [Tyr11]-Somatostatin

[Tyr11]-Somatostatin

[Tyr11]-Somatostatin is a neuroactive peptide utilized in proteomics research. It belongs to a class of neuroactive substances that play a role in modulating retinal physiology.
T10408 ATWLPPR Peptide TFA

Others Others
ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor and inhibits VEGF165 binding to NRP-1. It has the potential in reducing the early retinal damage caused by diabetes.
T71722 Angiogenesis inhibitor BT2

Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, angiogenesis, and inflammation, interacting with MEK1, suppressing retinal CD31, pERK, VCAM-1, and VEGF-A165 expression.
T79077 ROCK-IN-6

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
ROCK-IN-6为一有效的ROCK2抑制剂,其IC50值为2.19 nM。该化合物具备用于研究青光眼及视网膜疾病的潜力。
T80443 ω-Conotoxin MVIID

SNX-238

Calcium Channel Membrane transporter/Ion channel; Metabolism
ω-Conotoxin MVIID (SNX-238) 是芋螺肽,能抑制ω-Conotoxin-GVIA敏感的高阈值Ca2+电流于鱼类视网膜神经节细胞。
T68547 SNJ-1945

SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly. SNJ-1945 protects SH-SY5Y cells against MPP(+) and rotenone. SNJ-1945 reduces murine retinal cell death in vitro and in vivo. SNJ-1945 has good aqueous solubility, can prevents the heart from KCl arrest-reperfusion injury associated with the impairment of total Ca(2+) handling by inhibiting the proteolysis of alpha-fodrin a...
T37453 Butyryl-L-carnitine (chloride)

Butyryl-L-carnitine is a butyrate ester of carnitine. It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human retinal pigment epithelial (HRPE) cells (IC50s = 1.5 μM and 4.6 mM, respectively).
T35889 PB2

PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficacy in promoting RGC survival. Notably, PB2 exhibits superior permeability compared to TCEP. Serving as a potent reducing agent, PB2 provides robust neuroprotection for RGCs[1].
T74699 Avacincaptad pegol

Avacincaptad pegol 是核酸适配体,作为 C5 补体抑制剂,用以减轻炎症导致的视网膜色素上皮 (RPE) 损伤。该化合物可用于研究 stargardt 黄斑营养不良 (STGD1) 与地理萎缩 (GA)。
T79080 ROCK-IN-7

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
ROCK-IN-7(compound 9)作为ROCK激酶抑制剂,主要应用于眼部疾病(包括青光眼及视网膜疾病)的研究领域。
T69990 Ruboxistaurin mesylate monohydrate

Ruboxistaurin mesylate monohydrate is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
T37820 Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)

Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retinal ischemia. bFGF (1-24) corresponds to amino acid residues 1-24 of the full length peptide.
T3689L Ruboxistaurin mesylate

LY-333531,LY333531,LY 333531,LY-333531 Mesylate

Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/
T76987 Tarcocimab

Tarcocimab (OG1953) 是一种人源化抗VEGFA 单克隆抗体 (IgG1 型)。Tarcocimab 可用于视网膜静脉阻塞 (RVO) 和湿性老年性黄斑变性 (AMD) 的研究。
T38220 11-cis Retinol

11-cisRetinol is an isomer of vitamin A . It is formed from vitamin A,viaatrans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual cycle.1,211-cisRetinol is an agonist of salamander and human red rod opsins expressed in COS cells and an inverse agonist of salamander red cone opsin, as well as human red and green cone opsins expressed in COS cells.3It promotes pigment formation in cone, but not rod, photorec...
T83681 IRBP (1-20) (human, rat) TFA

IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)

IRBP1-20(1-20)是IRBP的一个十二肽片段,亦称视黄醇结合蛋白3,负责运输视锥细胞中的视黄醇和视黄醛至视网膜色素上皮,参与色素再生。在携带H-2b等位基因型的C57BL/6小鼠中,IRBP1-20用于诱导自身免疫性葡萄膜视网膜炎。IRBP1-20(3 µM)能增加初级小鼠脾淋巴细胞分泌IL-4、IL-5和IL-6的水平。用IRBP1-20免疫并再次挑战,可增加IFN-γ缺乏小鼠的耳部肿胀、眼部血管炎症、免疫细胞浸润和视锥细胞层损伤,以及视网膜脱落。
T37577 Glycogen Phosphorylase Inhibitor

Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic glycogenolysis in vivo. Glycogen phosphorylase inhibitor has been used to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells.
T35888 PB1

PB1 is a highly-effective intracellular disulfide reducing agent with notable attributes such as excellent cell permeability, the capacity to generate a substantial intracellular concentration gradient, and remarkable stability. It serves as a borane-protected TCEP (tris(2-carboxyethyl)phosphine) analogue. PB1 demonstrates the potential to enhance the survival of retinal ganglion cells following axotomy in vitro at concentrations in the nanomolar and picomolar range. Consequently, PB1 has proven...
T38462 PF-04577806

PF-04577806 is a potent, selective, and ATP competitive inhibitor of the protein kinase C (PKC). It exhibits significant inhibitory activity against various isoforms of PKC, including PKCα, PKCβI, PKCβII, PKCγ, and PKCθ, with IC50 values of 2.4 nM, 8.1 nM, 6.9 nM, 45.9 nM, and 29.5 nM, respectively. Furthermore, PF-04577806 has the ability to reverse retinal vascular leakage in diabetic rats.
T61604 PKC-IN-4

PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM. In vitro studies have demonstrated that PKC-IN-4 effectively suppresses NF-κB activity induced by TNF-α. Moreover, this compound effectively impedes the permeability of the retinal vasculature, induced by both VEGF and TNFα. [1]
T35990 ent-8-iso-15(S)-Prostaglandin F2α

ent-8-iso-15(S)-Prostaglandin F2α

Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood pla...
T83700 IRBP (651-670) (human) TFA

IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)

IRBP651-670(Interphotoreceptor retinoid-binding protein (651-670))是IRBP(亦称为retinoid-binding protein 3)的肽段,参与色素再生,通过将视黄醇和视黄醛从光感受细胞传输到视网膜色素上皮。在C57BL/6小鼠中,利用IRBP651-670诱导自身免疫性葡萄膜炎,这些小鼠携带H-2b单体型。用IRBP651-670(300 µg/动物)免疫增加了小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平,免疫细胞浸润及光感受器损伤。

化合物

11-cis Retinal
Cat.No: T38219
Synonym:
Target:
Nitrofen
Cat.No: T39280
Synonym:
Target: Others
WS3
Cat.No: T2055
Synonym:
Target: EGFR, IκB/IKK
CYM5442
Cat.No: T2026
Synonym:
Target: S1P Receptor, LPL Receptor
INCA-6
Cat.No: T21807
Synonym: Triptycene-1,4-quinone
Target: Others
SPHINX31
Cat.No: T5194
Synonym:
Target: Serine/threonin kinase
Retinaloxime
Cat.No: T34299
Synonym: trans-Retinaloxime
Target:
3-Diazirinophenylretinal
Cat.No: T29395
Synonym:
Target:
Sulbutiamine
Cat.No: T5913
Synonym: 舒布硫胺,Bisibuthiamine
Target: Antioxidant
hGPR91 antagonist 3
Cat.No: T62858
Synonym:
Target: GPR
Mopidamol
Cat.No: T25829
Synonym: RA233,RA 233,RA-233,Rapenton,OLX 102
Target: PDE
BiP inducer X
Cat.No: T30480
Synonym: BIX
Target: Apoptosis
Brr2-IN-3
Cat.No: T22282
Synonym: Brr2 Inhibitor 9,Brr2 Inhibitor C9
Target: Others
NMDAR/TRPM4-IN-2
Cat.No: T72662
Synonym:
Target: ERK, TRP/TRPV Channel, NMDAR, iGluR
HIOC
Cat.No: T37081
Synonym:
Target:
9-cis-β-Carotene
Cat.No: T13524
Synonym:
Target: Others
SH-11037
Cat.No: T70329
Synonym:
Target:
Neurotensin-related hexapeptide
Cat.No: TP2393
Synonym: Lant-6
Target:
AL-1
Cat.No: T29809
Synonym: AL 1,AL1
Target:
Pyr-Gly
Cat.No: T81341
Synonym:
Target:
CU239
Cat.No: T71715
Synonym:
Target:
Cremastranone
Cat.No: T71488
Synonym:
Target:
Arginyl-Glutamine
Cat.No: T76574
Synonym:
Target:
Quininib
Cat.No: T28487
Synonym:
Target:
Pyridinium bisretinoid A2E TFA
Cat.No: T78404
Synonym: A2E TFA
Target: Apoptosis
ONL-1204
Cat.No: T69972
Synonym:
Target:
YC-001
Cat.No: T73476
Synonym:
Target:
ent-8-iso Prostaglandin F2α
Cat.No: T36617
Synonym: ent-8-iso Prostaglandin F2α
Target:
[Tyr11]-Somatostatin
Cat.No: T40680
Synonym: [Tyr11]-Somatostatin
Target:
ATWLPPR Peptide TFA
Cat.No: T10408
Synonym:
Target: Others
Angiogenesis inhibitor BT2
Cat.No: T71722
Synonym:
Target:
ROCK-IN-6
Cat.No: T79077
Synonym:
Target: ROCK
ω-Conotoxin MVIID
Cat.No: T80443
Synonym: SNX-238
Target: Calcium Channel
SNJ-1945
Cat.No: T68547
Synonym:
Target:
Butyryl-L-carnitine (chloride)
Cat.No: T37453
Synonym:
Target:
PB2
Cat.No: T35889
Synonym:
Target:
Avacincaptad pegol
Cat.No: T74699
Synonym:
Target:
ROCK-IN-7
Cat.No: T79080
Synonym:
Target: ROCK
Ruboxistaurin mesylate monohydrate
Cat.No: T69990
Synonym:
Target:
Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)
Cat.No: T37820
Synonym:
Target:
Ruboxistaurin mesylate
Cat.No: T3689L
Synonym: LY-333531,LY333531,LY 333531,LY-333531 Mesylate
Target:
Tarcocimab
Cat.No: T76987
Synonym:
Target:
11-cis Retinol
Cat.No: T38220
Synonym:
Target:
IRBP (1-20) (human, rat) TFA
Cat.No: T83681
Synonym: IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)
Target:
Glycogen Phosphorylase Inhibitor
Cat.No: T37577
Synonym:
Target:
PB1
Cat.No: T35888
Synonym:
Target:
PF-04577806
Cat.No: T38462
Synonym:
Target:
PKC-IN-4
Cat.No: T61604
Synonym:
Target:
ent-8-iso-15(S)-Prostaglandin F2α
Cat.No: T35990
Synonym: ent-8-iso-15(S)-Prostaglandin F2α
Target:
IRBP (651-670) (human) TFA
Cat.No: T83700
Synonym: IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)
Target:
Cat. No. Product Name Target Signaling Pathways
T5256 All-trans-retinal

视黄醛,All trans-Retinal,Retinaldehyde,Vitamin A aldehyde

Others; Endogenous Metabolite Metabolism; Others
All-trans-retinal (Vitamin A aldehyde) 是视网膜中维生素A 代谢物之一。 生理条件下,它再生为视觉发色团,11-顺式-视黄醛。
T19169 9-cis-Retinal

Others Others
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and maturation of rod photoreceptors in r
T12095 Monomethyl fumarate

GPR; Drug Metabolite Endocrinology/Hormones; GPCR/G Protein; Metabolism
Monomethyl fumarate 是 Dimethyl fumarate 的活性代谢产物。Monomethyl fumarate 是一种 GPR109A 激动剂。Monomethyl fumarate 是一种 GPR109A 激动剂具有用于多种神经保护途径和其他视网膜疾病模型的潜力。
T0685 Retinyl acetate

Vitamin A acetate,Retinyl (Retinol) Acetate,视黄醇乙酸酯(维生素A醋酸酯),Retinol acetate,视黄醇乙酸酯

Retinyl acetate (Vitamin A acetate) 是一种视黄醇的合成乙酸酯形式衍生物,有抗肿瘤和化学预防活性的潜能。
T40942 (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, an antiangiogenic homoisoflavonoid, exhibits activity against human retinal microvascular endothelial cells.
T75608 Myricetin 3-O-α-L-arabinopyranoside

Myricetin 3-O-α-L-arabinopyranoside 抑制 A2E 光氧化诱导的RPE 细胞死亡。Myricetin 3-O-α-L-arabinopyranoside 对视网膜变性具有保护作用,可保护蓝光 (BL) 诱导对 RPE 细胞和小鼠模型的损伤。
TQ0199 Ginsenoside Rh3

人参皂苷 RH3

Antioxidant; Nrf2; Antifungal Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
Ginsenoside Rh3 是一种从人参 C. A. Mey 中提取的天然产品。Ginsenoside Rh3 具有抗真菌和抗氧化活性,处理人视网膜细胞可诱导 Nrf2 。
T10348 Apigenin-7-diglucuronide

Others Others
Apigenin-7-diglucuronide is a flavonoid glycoside that exists in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. It protects retinas against bright light-induced photoreceptor degeneration through the inhibition of reti
T38179 C16 3'-sulfo Galactosylceramide (d18:1/16:0)

C16 3'-sulfo Galactosylceramide (d18:1/16:0)

Others Others
C16 3'-sulfo Galactosylceramide (d18:1/16:0)是硫酸盐类糖脂的一种。C16 3'-sulfo Galactosylceramide (d18:1/16:0)是在猪脑和血浆中发现的一种比较丰富的硫化物,在小鼠的整个发育过程中会有所减少。C16 3'-sulfo Galactosylceramide (d18:1/16:0)在体外可抑制视网膜神经节细胞生长。C16 3'-sulfo Galactosylceramide (d18:1/16:0)已被用作量化大鼠小脑和多发性硬化症患者分离的白质中的硫化物的参照物。

天然产物

All-trans-retinal
Cat.No: T5256
Synonym: 视黄醛,All trans-Retinal,Retinaldehyde,Vitamin A aldehyde
Target: Others, Endogenous Metabolite
9-cis-Retinal
Cat.No: T19169
Synonym:
Target: Others
Monomethyl fumarate
Cat.No: T12095
Synonym:
Target: GPR, Drug Metabolite
Retinyl acetate
Cat.No: T0685
Synonym: Vitamin A acetate,Retinyl (Retinol) Acetate,视黄醇乙酸酯(维生素A醋酸酯),Retinol acetate,视黄醇乙酸酯
Target:
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
Cat.No: T40942
Synonym:
Target:
Myricetin 3-O-α-L-arabinopyranoside
Cat.No: T75608
Synonym:
Target:
Ginsenoside Rh3
Cat.No: TQ0199
Synonym: 人参皂苷 RH3
Target: Antioxidant, Nrf2, Antifungal
Apigenin-7-diglucuronide
Cat.No: T10348
Synonym:
Target: Others
C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Cat.No: T38179
Synonym: C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Target: Others
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