首页工具

C16 3'-sulfo Galactosylceramide (d18:1/16:0)

产品编号 T38179 CAS 89771-78-8

别名: C16 3'-sulfo Galactosylceramide (d18:1/16:0)

C16 3'-sulfo Galactosylceramide (d18:1/16:0)是硫酸盐类糖脂的一种。C16 3'-sulfo Galactosylceramide (d18:1/16:0)是在猪脑和血浆中发现的一种比较丰富的硫化物，在小鼠的整个发育过程中会有所减少。C16 3'-sulfo Galactosylceramide (d18:1/16:0)在体外可抑制视网膜神经节细胞生长。C16 3'-sulfo Galactosylceramide (d18:1/16:0)已被用作量化大鼠小脑和多发性硬化症患者分离的白质中的硫化物的参照物。

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

C16 3'-sulfo Galactosylceramide (d18:1/16:0) Chemical Structure

C16 3'-sulfo Galactosylceramide (d18:1/16:0), CAS 89771-78-8

规格	价格/CNY		货期	数量
1 mg	￥ 11,680		待询

大包装超大折扣，点击咨询

C16 3'-sulfo Galactosylceramide (d18:1/16:0) 的其他形式现货产品:

C16 Sphingomyelin (d18:1/16:0) C16 Ceramide

其他形式的 C16 3'-sulfo Galactosylceramide (d18:1/16:0):

C16 Sphingomyelin (d18:1/16:0)
现货
C16 Ceramide
现货
13C C16 Sphingomyelin (d18:1/16:0)
询价
C16 Globotriaosylceramide (d18:1/16:0)
询价
C16 Lactosylceramide (d18:1/16:0)
询价
C16 Galactosylceramide (d18:1/16:0)
询价

选择批次

更多批次查询请联系客服

天然产物信息

生物活性

化学信息

存储 & 溶解度

参考文献

结构类型

天然产物 > 其他

产品描述	C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a sulfated glycolipid.C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice.C16 3'-sulfo Galactosylceramide is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice.C16 3'-sulfo Galactosylceramide is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice. C16 3'-sulfo Galactosylceramide (d18:1/16:0) inhibits retinal ganglion cell growth in vitro.C16 3'-sulfo Galactosylceramide (d18:1/16:0) has been used as an internal standard for quantifying C16 3'-sulfo Galactosylceramide (d18:1/16:0) in rat cerebellum and white matter isolated from patients with multiple sclerosis. reference for sulphides.
体外活性	C16:0 sulfatide (20 nmol/ml) inhibits glucose-stimulated insulin secretion by reducing the sensitivity of the K(ATP) channels to ATP. (The half-maximal inhibitory concentration is 10.3 and 36.7 micromol/l in the absence and presence of C16:0 sulfatide, respectively.) [1] C16:0 sulfatide (20 nmol/ml for 30 min) increased whole-cell K(ATP) currents at intermediate glucose levels and reduced the ability of glucose to induce membrane depolarization, reduced electrical activity, and increased the cytoplasmic free Ca2+ concentration. Recordings of cell capacitance revealed that C16:0 sulfatide increased Ca2+-induced exocytosis by 215%. This correlated with a stimulation of insulin secretion by C16:0 sulfatide in intact rat islets exposed to diazoxide and high K+.[1] C16:0 sulfatide (20 nmol/l for 24 h) did not modulate glucagon secretion from intact rat islets.[1]
体内活性	C16:0 sulfatide (1 µmol/kg,1 mL ; Zucker rats) resulted in significantly elevated glucose-stimulated insulin secretion (60-80% increase, p < 0.05), without significant changes in glucose tolerance. The treatment was associated with an ameliorated first-phase insulin response (3-4-fold, p = 0.009, 0.016) and a 60% increase of pancreatic sulfatide content (p = 0.001), possible by an uptake of C16:0 sulfatide. The fasting hyperinsulinaemia and blood glucose levels were unchanged.[2]

别名	C16 3'-sulfo Galactosylceramide (d18:1/16:0)
分子量	780.1
分子式	C40H77NO11S
CAS No.	89771-78-8

存储

store at low temperature　|　Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

Chloroform:Methanol (2:1): Soluble

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

质量

浓度

容积

分子量

浓度 (起始)

容积 (起始)

浓度 (终)

容积 (终)

溶液体积

质量

配液浓度

参考文献

1. Buschard K, et al. C16:0 sulfatide inhibits insulin secretion in rat beta-cells by reducing the sensitivity of KATP channels to ATP inhibition. Diabetes. 2006 ; 55(10):2826-2834. 2. Blomqvist M, et al. In vivo administration of the C16:0 fatty acid isoform of sulfatide increases pancreatic sulfatide and enhances glucose-stimulated insulin secretion in Zucker fatty (fa/fa) rats. Diabetes Metab Res Rev. 2005 ; 21(2):158-166. 3. Blomqvist M, et al. Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models. APMIS. 2003 ; 111(9):867-877. 4. Saxena K, et al. Unusual hydration properties of C16:0 sulfatide bilayer membranes. Biophys J. 2000 ; 79(1):385-393. 5. Buschard K, et al. The C24:0 Sulfatide Isoform as an Important Molecule in Type 1 Diabetes. Front Biosci (Landmark Ed). 2022 ; 27(12):331.

剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

剂量

mg/kg

每只动物体重

给药体积

μL

动物数量

第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

% DMSO+

% +