Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 μg | ¥ 2,100 | 35日内发货 | ||
50 μg | ¥ 3,990 | 35日内发货 | ||
100 μg | ¥ 7,520 | 35日内发货 |
产品描述 | Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay. |
别名 | ent-8-iso-15(S)-Prostaglandin F2α |
分子量 | 354.48 |
分子式 | C20H34O5 |
CAS No. | 214748-66-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): >10 mg/mL
DMF: >100 mg/mL
DMSO: >100 mg/mL
10 mM Na2CO3: >6.5 mg/mL
Ethanol: >100 mg/mL
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
ent-8-iso-15(S)-Prostaglandin F2α 214748-66-0 ent-8-iso-15Prostaglandin F2a ent-8-iso-15Prostaglandin F2alpha ent-8-iso-15(S)-Prostaglandin F-2α ent8iso15(S)Prostaglandin F2α ent 8 iso 15(S) Prostaglandin F2α ent-8-iso-15Prostaglandin F2α Inhibitor inhibitor inhibit