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Search Results for " redox "

58

抑制剂 & 化合物

18

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T40732	TMPD dihydrochloride
	TMPD dihydrochloride 是酶促转化氧化还原的活性底物和用于还原血红素过氧化物酶的电子供体。
T7545	6-Aminonicotinamide	Others	Others
	6-Aminonicotinamide 是一种竞争性 NADP+依赖性酶，是一种烟酰胺抗代谢药，葡萄糖 6-磷酸脱氢酶抑制剂 (Ki=0.46 μM)。它干扰糖酵解，导致 ATP 耗竭，并与 DNA 交联化学疗法药物，如Cisplatin，协同杀死癌细胞。
T0223	Tetrahydroxyquinone 4-benzoquinone,四羟基苯醌,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone	Apoptosis; Antioxidant; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Tetrahydroxyquinone (Tetroquinone) 是一种苯醌，是一种抗白内障剂，具有氧化还原活性。它可与半醌自由基一起参与氧化还原循环，导致活性氧形成。
T7714	Temocapil	Tyrosinase	Proteases/Proteasome
	Temocapil 是一种酪氨酸激酶抑制剂。
T6698	Temocapril hydrochloride CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利	RAAS	Endocrinology/Hormones
	Temocapril hydrochloride (CS-622 HCl) 是血管紧张素转化酶 (ACE) 抑制剂。Temocapril HCl 能够用于充血性心力衰竭、急性心肌梗死、高血压、胰岛素抵抗和肾脏疾病的研究。
TD0103	Safranin 碱性红 2,Safranine T,Basic Red 2	Others	Others
	Safranin (Basic Red 2) 是一种经典的吩嗪染料，具有平面结构和阳离子电荷，能够轻易插入包括 DNA、蛋白质在内的生物大分子。它在学术领域被广泛用作光谱探针及指示剂，可作为金属离子浓度测定中的氧化还原指示剂。
TP1604L	Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others	Others
	Thioredoxin reductase peptide acetate(950890-23-0 free base) 对应于硫氧还蛋白还原酶 (TrxR) 中的 53–67 位残基，用于硫氧还蛋白还原酶研究。哺乳动物硫氧还蛋白还原酶 (TR) 催化硫氧还蛋白 (Trx) 的氧化还原活性二硫键的还原，并且在结构和谷胱甘肽还原酶的作用机制，除了 C 末端的 16 个氨基酸延伸部分含有一个罕见的连位硒硫键。
T27287	Estredox E 2CDS,E-2-CDS,IDR 90104,E-2CDS,IDR-90104,E 2 CDS
	Estredox, an estrogen receptor agonist, is used potentially for the treatment of vasomotor symptoms.
TP1604	Thioredoxin reductase peptide
	Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfide bond of thioredoxin (Trx) and is
TP1375	Thioredoxin reductase peptide TFA
	Thioredoxin reductase peptide TFA corresponds to residues 53-67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research..
T19245	Cobalt phthalocyanine Cobaltous phthalocyanine,酞菁钴,Phthalocyanine cobalt complex,Cobalt(II) phthalocyanine	Others	Others
	Cobalt phthalocyanine (Phthalocyanine cobalt complex) 是氧化还原反应的催化剂，已经成功催化醛和酮从醛肟和酮肟中的有氧再生。
T7323	BCI-215	Phosphatase	Metabolism
	BCI-215 是高效肿瘤细胞选择性的双重特异性磷酸酶DUSP-MKP 抑制剂。它对肿瘤细胞有细胞毒性，但对正常细胞无毒性。
T38013	Sonlicromanol hydrochloride
	Sonlicromanol hydrochloride (KH176), a derivative of Trolox, is a ROS-redox modulator that effectively crosses the blood-brain barrier. It is specifically employed in the investigation of mitochondrial disorders[1].
T15213	Emeramide BDTH2,N,N'-二(2-巯基乙基)间苯二甲酰胺	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Emeramide (BDTH2) 是一种硫醇氧化还原抗氧化剂，也是一种重金属螯合剂。
T5426	DMNQ	Reactive Oxygen Species; ROS	Immunology/Inflammation; Metabolism; NF-κB
	DMNQ 是氧化还原循环剂，以浓度依赖性方式在细胞内产生超氧化物和过氧化氢，能够诱导ROS 增加。
TD0104	Methyl purple	Others	Others
	Methyl purple 是一种引入的醌-酰亚胺氧化还原染料，已被证明是一种对叶绿体中光系统 I 活性异常敏感的监测器。
T5364	TBHQ tert-Butylhydroquinone,特丁基对苯二酚,叔丁基氢醌	Apoptosis; ERK; Others; Ferroptosis; Nrf2; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; MAPK; Others
	TBHQ (tert-Butylhydroquinone) 是一种抗氧化剂，可通过对氧化还原敏感的转录因子 Nrf2 诱导抗氧化反应。它也是一种ERK 激活剂，逆转 Dehydrocorydaline 对黑素瘤细胞增殖的抑制作用。
T19752	S-Methoprene ZR2458,ZR 2458,ZR-2458,(+)-Methoprene,Preco
	S-Methoprene (ZR2458) 是保幼激素的类似物，可用作杀虫剂。 S-Methoprene 改变细胞色素氧化酶的氧化还原活性并诱导雄性分化。
T4414	Eprenetapopt APR-246,PRIMA-1Met	Apoptosis; Others; Ferroptosis; p53; Autophagy	Apoptosis; Autophagy; Others
	Eprenetapopt (PRIMA-1Met) 是一种在 TP53突变细胞中恢复野生型 p53功能的小分子，可引发肿瘤细胞凋亡，还抑制硒蛋白硫氧还蛋白还原酶 1。
T83633	1-N-Methyl-4-mercaptohistidine disulfide	Others	Others
	1-N-Methyl-4-mercaptohistidine disulfide 是一种潜在的杜氏菌叶绿体偶联因子1氧化还原调节剂，是氧化形式的卵硫醇A，抑制光触发的CF1 ATP酶活性。
T39664	Ethaselen BBSKE
	Ethaselen (BBSKE), a selective thioredoxin reductase (TrxR) inhibitor, is orally active with IC50s of 0.5 and 0.35 μM for wild-type human TrxR1 and rat TrxR1, respectively. Ethaselen specifically binds to the unique selenocysteine-cysteine redox pair located in the C-terminal active site of mammalian TrxR1. As an organoselenium compound, it demonstrates potent antitumor activity against non-small cell lung cancer (NSCLC) by targeting TrxR.
T16503	PF-4191834 PF-04191834	Lipoxygenase	Metabolism
	PF-4191834 是 5-Lipoxygenase (5-LOX) 的非铁螯合和非氧化还原抑制剂，IC50 为 229 nM。 PF-4191834 对 5-LOX 的特异性比 12-LOX 和 15-LOX 高约 300 倍，并且对环氧合酶没有活性。 PF-4191834 可用于炎症和疼痛的研究。
Fr14395	2,2'-Bipyridine
	2,2'-Bipyridine 是一种独特的生物活性天然产物分子支架，常用于许多螯合配体的核心结构。2,2'-Bipyridine 在催化中心的排列中起到桥梁的作用。2,2'-Bipyridine 具有良好的氧化还原稳定性和升糖活性。
T27139	Decylubiquinone
	Decylubiquinone is an analog of ubiquinone. It increases mitochondrial function in synaptosomes. Decylubiquinone inhibits the redox-activated mitochondrial permeability transition.
T25773	Mal-RP MalRP,Mal RP
	Mal-RP is a quantitative chemical probe for live-cell labeling and imaging of proteins that are sensitive to redox modifications.
T20014	Patent Blue V calcium salt Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051
	Acid blue is a dark bluish synthetic triphenylmethane dye. It used as a food coloring. The color of the dye is pH-dependent. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. It is usable as a
T72121	Tetrahydroxyquinone monohydrate Tetrahydroxybenzoquinone monohydrate,Tetrahydroxy-1,4-benzoquinone monohydrate,Tetrahydroxy-1,4-benzoquinone monohydrate ; Tetrahydroxybenzoquinone monohydrate
	Tetrahydroxyquinone monohydrate (Tetrahydroxy-1,4-benzoquinone monohydrate)，为一种抗白内障药物，属于具氧化还原活性的苯醌类化合物。此化合物能通过与半醌自由基共同参与氧化还原循环过程中，促进活性氧 (ROS) 的生成。
T31159	Cysteinesulfenic acid L-Alanine, 3-sulfeno-,L-Cysteine sulfoxide,L-Cysteinesulfenic acid,S-(Propylcarbamoyl)cysteine
	Cysteinesulfenic acid is a protein-sulfenic acid involved in enzyme catalysis, redox regulation, and signal transduction.
T40995	Violuric acid
	Violuric acid is a redox mediator employed in the laccase system, specifically in the context of the violuric acid assay. This assay serves to verify and ensure the preservation of the high-redox potential characteristic of laccase throughout the process of directed evolution.
T24693	QD325 QD 325,QD-325
	QD325 is a potent redox modulator for the Treatment of Pancreatic Ductal Adenocarcinoma. Nascent RNA sequencing following treatments with QD325 revealed induction of stress responses in the nucleus, endoplasmic reticulum, and mitochondria of pancreatic ca
T79180	GLX481369
	GLX481369为具有氧化还原活性的化合物，同时作为Nox4抑制剂，展现出抗氧化能力。
T76101	Ascorbate oxidase
	Ascorbate oxidase（即维生素 C 氧化酶），作为一种氧化还原酶，在细胞外基质中的氧化还原调节中起作用。该酶催化抗坏血酸与氧之间的反应，生成脱氢抗坏血酸。
T70733	APX2009
	APX2009 is a second-generation APE1/Ref-1 redox-specific inhibitor. APX2009 significantly reduces NFkB transcriptional activity, survivin mRNA, and survivin protein levels. APX2009 decreases prostate cancer cell proliferation and induces cell cycle arrest.
T32392	Sonlicromanol KH-176,KH 176,KH176
	KH-176 is an effective intracellular REDOX regulator that targets reactive oxygen species, which are important in the pathogenesis of mitochondrial oxidative phosphorylation disorders and may be used to treat mitochondrial diseases.
T82186	Homoglutathione
	Homoglutathione，一种在真核生物中普遍存在且不可或缺的三肽，主要功能与细胞的氧化还原调节相关，并具有味觉调节作用。
T74363	Chol-TPP
	Chol-TPP 是一个线粒体靶向脂质体配体，可用于 pH -氧化还原反应。
T62910	Antibacterial agent 62
	Antibacterial agent 62 是一种新型氧化还原循环抗结核化合物，对生长和营养缺乏的表型耐药非生长细菌表现出显著的杀菌作用。
T80849	VU661
	VU661, 一种吩嗪甲酰胺类化合物，作为昼夜节律调节剂能促使昼夜节律周期延长，该小分子具备氧化还原活性。
T71849	STK683963
	STK683963 是细胞ATG4B 活性的强激活剂。STK683963 可以作为细胞中 ATG4B 氧化还原调节的介质。STK683963 可用于癌症研究。
T76116	L-Lactate dehydrogenase
	L-Lactate dehydrogenase (L-乳酸脱氢酶) 是一种氧化还原酶。L-Lactate dehydrogenase 在体内催化 NADH 将丙酮酸还原为 L-乳酸。
T31899	FY26 FY 26,FY-26
	FY26 is a potent Os(II) anticancer drug candidate, exerts its activity by generating reactive oxygen species and disrupting the redox balance in cancer cells Coadministration of FY26 and nontoxic doses of L-BSO allows the potentiation of its anticancer ac
T36066	NADP+ (sodium salt hydrate)
	NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling. For example, binding of NADP+ to β-subunits of Kv channels activates ion transport, whereas NADPH stabilizes channel inactivation. NADP+ is biosynth...
T37612	IBTP (iodide)
	IBTP is a lipophilic cation that is accumulated in mitochondria and forms stable thioether adducts in a thiol-specific manner. As a result, mitochondrial proteins that have changed thiol redox state following oxidative stress are selectively tagged with IBTP and can be separated by two-dimensional electrophoresis and isolated. IBTP-tagged proteins can also be evaluated by immunoblotting using an antibody directed against the triphenylphosphonium moiety of the IBTP molecule. IBTP has also been us...
T64076	Spermine Prodrug-1
	Spermine Prodrug-1 是一种氧化还原敏感的精胺前药。Spermine Prodrug-1 对野生型 (CMS-24949) 和精胺合酶基因 (SMS) 突变型 (CMS-26559, 和 CMS-6233) 成纤维细胞具有抑制作用，他们的 IC50 值分别为 326.7, 198.5, 和 244.1 μM。Spermine Prodrug-1 能够用于 Snyder Robinson 综合征的治疗。
T33631	Neocuproine Neocuproin
	Neocuproine 是一种铜（I）螯合剂，可增强电场刺激引起的输精管收缩的嘌呤能成分，常被用作配位试剂和铜离子检测剂。Neocuproine 与铜离子形成稳定的络合物，并可在某些化学反应和分析方法中起到催化作用。Neocuproine 作为铁和钴上的氧化还原活性配体平台，对NSC34细胞氧化损伤的保护作用。
T38351	DYn-2
	Mild oxidation can convert the sulfhydryl group of cysteine residues on proteins to cysteine-sulfenic acid derivatives (Cys-SOH). Protein sulfenylation, then, is a post-translational modification that is relevant to redox signaling. DYn-2 is a chemoselective probe for detecting sulfenylated proteins in intact cells. DYn-2 consists of 1,3-cyclohexanedione coupled to an alkyne moiety by a 3-carbon spacer. The cyclohexanedione group selectively reacts with protein sulfenic acid modifications. The a...
T36173	L-Glutathione, oxidized (sodium salt)
	Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The rat...
T72280	PBT434 methanesulfonate
	PBT434 methanesulfonate 为一种有效、口服活性并能穿透血脑屏障的α-synuclein aggregation抑制剂，同时担任铁螯合剂和跨细胞铁运输的调节剂。该化合物抑制铁介导的氧化还原活性及α-synuclein聚集，可有效防止SNpc神经元丢失，显示出在PD研究中的应用潜力。
T77252	Dihydrorhodamine 6G
	Dihydrorhodamine 6G (DHR 6G) 为 Rhodamine 6G 的还原型，作为线粒体荧光染料而被广泛应用。该化合物在原状态下无荧光性，但能轻易渗透大部分细胞，并由氧化物或细胞的氧化还原系统氧化为具有荧光的 Rhodamine 6G，进而在线粒体膜中累积。Dihydrorhodamine 6G 主要用于活性氧 (ROS) 的检测，包括超氧化物。
T79601	SPC-180002	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	SPC-180002是一种针对SIRT1/3的双重抑制剂，IC50值分别为1.13 μM和5.41 μM。该化合物可通过诱导ROS产生干扰氧化还原平衡，进而增强p21蛋白的稳定性并引起线粒体功能障碍，同时显著抑制细胞周期进程及癌细胞的增殖，并能激活Nrf2信号通路。

化合物

TMPD dihydrochloride

Cat.No: T40732

6-Aminonicotinamide

Cat.No: T7545

Target: Others

Tetrahydroxyquinone

Cat.No: T0223

Synonym: 4-benzoquinone,四羟基苯醌,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Cat.No: T7714

Target: Tyrosinase

Temocapril hydrochloride

Cat.No: T6698

Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利

Target: RAAS

Cat.No: TD0103

Synonym: 碱性红 2,Safranine T,Basic Red 2

Target: Others

Thioredoxin reductase peptide acetate

Cat.No: TP1604L

Synonym: Thioredoxin reductase peptide acetate(950890-23-0 free base)

Target: Others

Cat.No: T27287

Synonym: E 2CDS,E-2-CDS,IDR 90104,E-2CDS,IDR-90104,E 2 CDS

Thioredoxin reductase peptide

Cat.No: TP1604

Thioredoxin reductase peptide TFA

Cat.No: TP1375

Cobalt phthalocyanine

Cat.No: T19245

Synonym: Cobaltous phthalocyanine,酞菁钴,Phthalocyanine cobalt complex,Cobalt(II) phthalocyanine

Target: Others

Cat.No: T7323

Target: Phosphatase

Sonlicromanol hydrochloride

Cat.No: T38013

Cat.No: T15213

Synonym: BDTH2,N,N'-二(2-巯基乙基)间苯二甲酰胺

Target: Reactive Oxygen Species

Cat.No: T5426

Target: Reactive Oxygen Species, ROS

Cat.No: TD0104

Target: Others

Cat.No: T5364

Synonym: tert-Butylhydroquinone,特丁基对苯二酚,叔丁基氢醌

Target: Apoptosis, ERK, Others, Ferroptosis, Nrf2, Autophagy

Cat.No: T19752

Synonym: ZR2458,ZR 2458,ZR-2458,(+)-Methoprene,Preco

Cat.No: T4414

Synonym: APR-246,PRIMA-1Met

Target: Apoptosis, Others, Ferroptosis, p53, Autophagy

1-N-Methyl-4-mercaptohistidine disulfide

Cat.No: T83633

Target: Others

Cat.No: T39664

Synonym: BBSKE

Cat.No: T16503

Synonym: PF-04191834

Target: Lipoxygenase

2,2'-Bipyridine

Cat.No: Fr14395

Decylubiquinone

Cat.No: T27139

Cat.No: T25773

Synonym: MalRP,Mal RP

Patent Blue V calcium salt

Cat.No: T20014

Synonym: Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051

Tetrahydroxyquinone monohydrate

Cat.No: T72121

Synonym: Tetrahydroxybenzoquinone monohydrate,Tetrahydroxy-1,4-benzoquinone monohydrate,Tetrahydroxy-1,4-benzoquinone monohydrate ; Tetrahydroxybenzoquinone monohydrate

Cysteinesulfenic acid

Cat.No: T31159

Synonym: L-Alanine, 3-sulfeno-,L-Cysteine sulfoxide,L-Cysteinesulfenic acid,S-(Propylcarbamoyl)cysteine

Cat.No: T40995

Cat.No: T24693

Synonym: QD 325,QD-325

Cat.No: T79180

Ascorbate oxidase

Cat.No: T76101

Cat.No: T70733

Cat.No: T32392

Synonym: KH-176,KH 176,KH176

Homoglutathione

Cat.No: T82186

Cat.No: T74363

Antibacterial agent 62

Cat.No: T62910

Cat.No: T80849

Cat.No: T71849

L-Lactate dehydrogenase

Cat.No: T76116

Cat.No: T31899

Synonym: FY 26,FY-26

NADP+ (sodium salt hydrate)

Cat.No: T36066

Cat.No: T37612

Spermine Prodrug-1

Cat.No: T64076

Cat.No: T33631

Synonym: Neocuproin

Cat.No: T38351

L-Glutathione, oxidized (sodium salt)

Cat.No: T36173

PBT434 methanesulfonate

Cat.No: T72280

Dihydrorhodamine 6G

Cat.No: T77252

Cat.No: T79601

Target: Sirtuin

Cat. No.	Product Name	Target	Signaling Pathways
T8002	3-Hydroxycoumarin	Lipoxygenase	Metabolism
	3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂，近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。
T5692	Pyrroloquinoline quinone	Others; Endogenous Metabolite	Metabolism; Others
	Pyrroloquinoline quinone 是氧化还原辅助因子，一种阴离子型氧化还原循环原醌。它是哺乳动物的必需营养素，对免疫功能很重要。它是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。
T5693	Pyrroloquinoline quinone disodium salt 吡咯喹啉醌二钠盐,Methoxatin disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt) 一种阴离子型氧化还原循环原醌，作为氧化还原辅助因子。它是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。它是哺乳动物的必需营养素，对免疫功能很重要。
T65172	Flavin adenine dinucleotide FAD	Endogenous Metabolite	Metabolism
	Flavin adenine dinucleotide (FAD) 是一种氧化还原辅因子，是蛋白质的辅基，参与机体多种代谢反应。
T2844	Hyperoside Quercetin 3-galactoside,金丝桃甙,金丝桃苷,Hyperin	Others; Influenza Virus; Antifungal	Microbiology/Virology; Others
	Hyperoside (Hyperin) 是一种从Camptotheca acuminate 提取的黄酮，具有多种生物活性，如心肌保护、抗氧化还原和抗炎活性。
TN7087	2,5-dimethoxycyclohexa-2,5-diene-1,4-dio 2,5-二甲氧基-1,4-苯醌,2,5-DMBQ,Thermophillin,2,5-Dimethoxybenzoquinone,2,5-Dimethoxybenzo-1,4-quinone	Others	Others
	2,5-dimethoxycyclohexa-2,5-diene-1,4-dio (Thermophillin) 是一种天然产物。它的氧化还原循环是木材褐腐真菌腐烂中Fe2+和H2O2再生的还原当量来源。
TN1413	Atranorin 荔枝素，巴美灵,荔枝素	Endogenous Metabolite; NO Synthase; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
	Atranorin 是地衣的次生代谢产物，具有显着的抗伤害、抗炎和氧化还原活性，对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
TN1480	Cephaeline 吐根鹼,吐根酚碱	Virus Protease; Influenza Virus; HIF	Angiogenesis; Chromatin/Epigenetic; Microbiology/Virology
	Cephaeline 对受保护的原代 CLL 细胞具有高度活性（相对 IC50 为 35nM），并通过抑制 HIF-1α± 和扰乱细胞内氧化还原稳态发挥作用。
T22446	NADP disodium salt Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐	Others	Others
	NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子，是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子，可以被交替氧化 (NADP+) 和还原 (NADPH)。
T3415	Secoisolariciresinol diglucoside 亚麻木酚素,LGM2605	ROS	Immunology/Inflammation
	Secoisolariciresinol diglucoside (LGM2605) 在铁过载诱导的氧化还原炎症损伤的体外模型中具有细胞保护作用。 Secoisolariciresinol Diglucoside(25 mg/kg b.w.) 通过抑制 ROS 水平介导的酶和非酶抗氧化剂水平升高来防止肝脏受到过氧化损伤，从而发挥抗高血糖作用。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
T4721	β-Nicotinamide mononucleotide β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸	Others; Endogenous Metabolite	Metabolism; Others
	β-Nicotinamide mononucleotide (β-NM) 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物。β-nicotinamide mononucleotide 的作用包括其在细胞生化功能、心脏保护、糖尿病、肥胖相关并发症和阿尔茨海默病中的作用。
T4838	(S)-Malic acid L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是天然存在的二羧酸，是水果酸甜味的来源，常用作食品添加剂。
T27218	Dunnione (+/-)-Dunnione,dl-Dunnione
	Dunnione is an antifungal agent exerting its action primarily through initiation of redox cycling.
T35981	Biliverdin hydrochloride	Antioxidant	oxidation-reduction
	Biliverdin hydrochloride 是一种由血红素氧化形成的四吡咯水溶性化合物，具有潜在的抗氧化活性，参与胆绿素-胆红素氧化还原系统。
T4448	NADP
	NADP，也称为烟酰胺腺嘌呤二核苷酸磷酸，是各种代谢过程中电子转移所必需的重要氧化还原辅因子。它在促进细胞能量产生和维持细胞内氧化还原平衡方面发挥着关键作用。
T38036	Lumisterol
	Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. [1]. Anyamanee Chaiprasongsuk, et al. Protective Effects of Novel Derivatives of Vitamin D 3 and Lumisterol Against UVB-induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms. Redox Biol. 2019 Jun;24:101206.
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

3-Hydroxycoumarin

Cat.No: T8002

Target: Lipoxygenase

Pyrroloquinoline quinone

Cat.No: T5692

Target: Others, Endogenous Metabolite

Pyrroloquinoline quinone disodium salt

Cat.No: T5693

Synonym: 吡咯喹啉醌二钠盐,Methoxatin disodium salt

Target: Others, Endogenous Metabolite

Flavin adenine dinucleotide

Cat.No: T65172

Synonym: FAD

Target: Endogenous Metabolite

Cat.No: T2844

Synonym: Quercetin 3-galactoside,金丝桃甙,金丝桃苷,Hyperin

Target: Others, Influenza Virus, Antifungal

2,5-dimethoxycyclohexa-2,5-diene-1,4-dio

Cat.No: TN7087

Synonym: 2,5-二甲氧基-1,4-苯醌,2,5-DMBQ,Thermophillin,2,5-Dimethoxybenzoquinone,2,5-Dimethoxybenzo-1,4-quinone

Target: Others

Cat.No: TN1413

Synonym: 荔枝素，巴美灵,荔枝素

Target: Endogenous Metabolite, NO Synthase, Ras

Cat.No: TN1480

Synonym: 吐根鹼,吐根酚碱

Target: Virus Protease, Influenza Virus, HIF

NADP disodium salt

Cat.No: T22446

Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Target: Others

Secoisolariciresinol diglucoside

Cat.No: T3415

Synonym: 亚麻木酚素,LGM2605

Target: ROS

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

β-Nicotinamide mononucleotide

Cat.No: T4721

Synonym: β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸

Target: Others, Endogenous Metabolite

Cat.No: T4838

Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸

Target: Others, Endogenous Metabolite

Cat.No: T27218

Synonym: (+/-)-Dunnione,dl-Dunnione

Biliverdin hydrochloride

Cat.No: T35981

Target: Antioxidant

Cat.No: T4448

Cat.No: T38036

Cat.No: T35624

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