80
115
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36105 |
coumarin-SAHA
coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA |
||
Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanilide hydroxamic acid (c-SAHA) is a SAHA derivative where the anilino cap" group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC. [2] The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm | |||
T31017 |
Coumarin-TMP-Halo
Coumarin TMP Halo,CTH |
||
Coumarin-TMP-Halo is a specific fluorescent protein labeling agent. | |||
T5845 |
7ACC1
DEAC,香豆素D1421,Coumarin D 1421,7-(二乙胺基)-2-氧代-2-苯并吡喃-3-羧酸,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421 |
Monocarboxylate transporter | Membrane transporter/Ion channel |
7ACC1 (D 142) 抑制表达MCT1和MCT4肿瘤细胞的乳酸涌入,能选择性干扰肿瘤微环境乳酸通量。 | |||
T117521 |
7-BFC
7-Benzyloxy-4-(trifluoromethyl)coumarin,Y040-0031 |
P450 | Metabolism |
7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) 是一种香豆素类荧光底物,可作为细胞色素 P 450 的生物标记物,可用于研究 CYP 亚型和细胞色素 P 450 代谢。 | |||
T38324 |
Coumarin Boronic Acid
|
||
Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide.It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively. | |||
T37797 | Coumarin-Quinone Conjugate | ||
Coumarin-quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases.1It is comprised of a coumarin fluorophore conjugated to a ubiquinone analog that can be reduced by NADH:ubiquinone oxidoreductases. It has been used to measure the kinetic parameters of apoptosis-inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1). 1.Doll, S., Freitas, F.P., Shah, R., et al.FSP1 is a glutathione-independent ferroptosis suppressorNature575(7784)693-698(20... | |||
T38325 |
Coumarin Boronic Acid pinacolate ester
|
||
Coumarin boronic acid pinacolate ester (CBE) is a more soluble form of coumarin boronic acid that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide. Peroxynitrite oxidizes CBE into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively. | |||
T37926 |
7-Ethoxy-4-(trifluoromethyl)coumarin
|
||
7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively. 1.Buters, J.T.M., Schiller, C.D., and Chou, R.C.A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation o... | |||
T37365 |
7-hydroxy Coumarin sulfate (potassium salt)
|
||
7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS. | |||
T37364 |
7-hydroxy Coumarin Glucuronide (sodium salt)
|
||
7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism. | |||
T31015 |
Coumarin, 3-glyoxyloyl-
3-Glyoxylcoumaric aldehyde,3-Glyoxyloylcoumarin,Aldeide cumarin-3-gliossilica |
||
Coumarin, 3-glyoxyloyl-, is a coumarin analogue for treatment of various diseases. Substituting new functional groups at different positions of coumarin nucleus may be useful in the development of novel compounds for the treatment of cancer. | |||
T31016 |
Coumarin, 3-glyoxyloyl-8-methoxy-
3-Glyoxyloyl-8-methoxycoumarin,3-Glyoxyl-8-methoxycoumaric aldehyde |
||
Coumarin, 3-glyoxyloyl-8-methoxy- is a coumarin analogue for treatment of various diseases. Substituting new functional groups at different positions of coumarin nucleus may be useful in the development of novel compounds for the treatment of cancer. | |||
T82679 |
Coumarin hydrazine
|
||
Coumarin hydrazine,作为荧光化学探针(λex=420-450 /λem=468 nm),专用于细胞内蛋白质和脂质结合羰基的标记。 | |||
T66908 |
Coumarin 314
|
||
Coumarin 314 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66908,CAS号为 55804-66-5。 | |||
T82677 |
Coumarin-C2-TCO
|
||
Coumarin-C2-TCO,作为Coumarin的染料衍生物,通过其TCO基团能够与带有四嗪基团的分子发生逆电子需求Diels-Alder反应(iEDDA)。 | |||
T82675 |
Coumarin-PEG3-TCO
|
||
Coumarin-PEG3-TCO,一种含有3个PEG单元的香豆素衍生物,通过其TCO基团参与与含有四唑基团的分子的逆电子需求Diels-Alder反应(iEDDA)发挥作用。 | |||
T82674 |
Coumarin-PEG8-tetrazine
|
||
Coumarin-PEG8-tetrazine是一种含有8个PEG单元的Coumarin衍生物。该化合物具有一个Tetrazine基团,能够与含有TCO基团的分子发生逆电子需求Diels-Alder反应(iEDDA)。 | |||
T82676 |
Coumarin-PEG2-TCO
|
||
Coumarin-PEG2-TCO是一种含有2个PEG单元的香豆素衍生物。该化合物的TCO基团可通过逆电子需求Diels-Alder反应(iEDDA)与含有四唑基团的分子反应。 | |||
T82678 |
Coumarin-C2-exo-BCN
|
||
Coumarin-C2-exoBCN是一种Coumarin染料衍生物。该化合物含有亲脂性双齿大环配体exo-BCN,可用于合成大环复合物。在点击化学中,exo-BCN能在无催化剂条件下与含有叠氮基团的分子发生反应,生成稳定的三唑。 | |||
T123943 |
6,7-Bis(benzyloxy)coumarin
|
||
6,7-Bis(benzyloxy)coumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T123943,CAS号为 909-84-2。 | |||
T18933 |
Calcein Blue
|
Others | Others |
Calcein Blue 是含有亚氨基二乙酸结构的香豆素衍生物,是不渗透膜的荧光染料,也是金属荧光变色指示剂。 | |||
T77557 |
Coumarin343
|
||
Coumarin343对单羧酸转运蛋白 4有抑制作用,IC50值在0.01-100 µM。Coumarin343具有抗癌和抗菌活性。Coumarin343是一种香豆素染料。 | |||
T77674 |
3-Cyano-7-hydroxycoumarin
3-Cyanoumbelliferone |
||
3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) 是一种巨噬细胞游走抑制因子 (MIF) 互变异构酶抑制剂,Ki 为 2.9 μM。3-Cyano-7-hydroxycoumarin 属于香豆素衍生物,可被用作分子探针和荧光染料。 | |||
T77558 |
5,7-Dimethoxy-4-methylcoumarin
|
Antioxidant | oxidation-reduction |
5,7-Dimethoxy-4-methylcoumarin 具有潜在的抗氧化抗增殖和抗癌或活性。 | |||
T10115 |
3-Nitrocoumarin
3-nitrochromen-2-one |
Phospholipase | Metabolism |
3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) 是一个有效的、磷脂酶 C-γ (PLC-γ) 的选择性抑制剂。 | |||
T77564 |
Coumarin102
Exciton 480 |
||
Coumarin102 (Exciton 480)是一种荧光染料。Coumarin102对Monoamine oxidase B、MAO-B和MAO-A具有较弱的抑制活性,可用来研究神经系统疾病。 | |||
T8677 |
3,4 Dichloroisocoumarin
|
Others; Serine Protease; Cysteine Protease | Others; Proteases/Proteasome |
3,4 Dichloroisocoumarin 是一种颗粒酶、组织蛋白酶 G 和中性粒细胞弹性蛋白酶抑制剂 | |||
T7696 |
3-Cyano-7-ethoxycoumarin
|
Others | Others |
3-Cyano-7-ethoxycoumarin 是荧光色素 P-450底物,在酶切时获得蓝色荧光产物。 | |||
TD0078 |
Succinimidyl 7-methoxycoumarin-3-carboxylate
7-甲氧基-3-羧基香豆素琥珀酰亚胺酯,7-Methoxycoumarin-3-carboxylic acid, succinimidyl ester |
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7-Methoxycoumarin-3-carboxylic acid may be used as a reference compound in the purification, separation and analysis of coumarin compounds. | |||
T83363 |
3-Acetyl-6-bromocoumarin
|
||
3-Acetyl-6-bromocoumarin,一种香豆素,具有约56%的强抗氧化活性。 | |||
TD0075 |
7-Hydroxy-4-methylcoumarin-3-acetic acid
|
||
7-Hydroxy-4-methylcoumarin-3-acetic acid is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin is increasingly used to label peptides, nucleotides and carbohydrates. | |||
TD0074 |
N-Succinimidyl 7-hydroxycoumarin-3-carboxylate
7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester |
||
7-Hydroxycoumarin-3-carboxylic acid, SE is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. This coumarin is also increasingly used to label peptides, nucleotides and carbohydrates. | |||
T83256 |
7-(Dimethylamino)-4-methylcoumarin
|
||
7-(Dimethylamino)-4-methylcoumarin,一种香豆素,主要用于香豆素荧光增白剂溶液研究。 | |||
T37000 |
7-Azido-4-methylcoumarin
|
||
7-Azido-4-methylcoumarin (AzMC) is a coumarin fluorescent probe for hydrogen sulfide (H2S).1 AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species. AzMC displays excitation/emission maxima of 340/445 nm, respectively. |1. Chen, B., Li, W., Lv, C., et al. Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues. Analyst 138(3), 946-951 (2013). | |||
T7037 |
7-Acetoxy-4-methylcoumarin
7-乙酰氧基-4-甲基香豆素,MU-Ac |
Others | Others |
7-Acetoxy-4-methylcoumarin 是羧酸酯酶的荧光底物,在切割时会产生蓝色荧光溶液。该化合物已用于非质子介质(一种细胞膜环境模拟物),以研究分散在水介质中的模型生物膜的超氧化物和相关的氧自由基反应。由于 AchE 能够裂解和激活 7-Acetoxy-4-methylcoumarin,因此荧光底物已被用于研究 AchE 抑制剂 Tacrine·HCl (sc-200172)。该化合物也已从 Trigonella foenum graceum 中分离出来。 | |||
T83250 |
7-Acetoxy-4-bromomethylcoumarin
|
||
7-Acetoxy-4-bromomethylcoumarin是作为脂肪酸新型荧光探针。 | |||
T32784 |
Liqcoumarin
|
||
Liqcoumarin 属于羟基香豆素类。在细胞内,它主要位于细胞质中。在人体外,它可以在草药、香料和茶中找到。这使得Liqcoumarin 成为这些食品消费的潜在生物标志物。 | |||
T29485 | 7-Lysylalanyl-4-methylcoumarinamide | ||
7-Lysylalanyl-4-methylcoumarinamide is a Fluorogenic substrate for dipeptidyl aminopeptidase. | |||
T124089 | Preethuliacoumarin | ||
Preethuliacoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124089,CAS号为 85431-45-4。 | |||
T40888 |
3-Acetamidocoumarin
|
||
3-Acetamidocoumarin, a compound significant in biology and medicine, exhibits physiological effects and is utilized in treating various conditions, including burns, brucellosis-rheumatic diseases, and cancer. | |||
T83324 |
4-Bromomethyl-6,7-dimethoxycoumarin
|
||
4-Bromomethyl-6,7-dimethoxycoumarin 作为羧酸在色谱检测中的荧光标记物使用。 | |||
TD0073 |
7-Hydroxycoumarin-3-carboxylic acid
|
||
7-Hydroxycoumarin-3-carboxylic acid is a blue fluorophores for labeling proteins and nucleic acids mostly through the in situ formation of its succinimidyl ester catalyzed by EDAC. | |||
T67631 |
4,6-Dimethyl-7-ethylaminocoumarin
|
||
4,6-Dimethyl-7-ethylaminocoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67631,CAS号为 26078-25-1。 | |||
T125085 |
5-Methoxy-7-hydroxycoumarin
|
||
5-Methoxy-7-hydroxycoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125085。 | |||
T124649 |
5,6,7,8-Tetramethoxycoumarin
|
||
5,6,7,8-Tetramethoxycoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124649。 | |||
T130450 |
3,4,8-Trihydroxycoumarin
|
||
3,4,8-Trihydroxycoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T130450。 | |||
T123948 | 6,8-Di-O-methylcitreoisocoumarin | ||
6,8-Di-O-methylcitreoisocoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T123948。 | |||
T83249 |
7-Aminocoumarin
|
||
7-Aminocoumarin,高荧光性化合物,用于荧光增白及探针应用。 | |||
T126231 |
6,8-Dihydroxy-3-methylisocoumarin
|
||
6,8-Dihydroxy-3-methylisocoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126231,CAS号为 1204-37-1。 | |||
T125251 | 8-Geranyl-7-hydroxycoumarin | ||
8-Geranyl-7-hydroxycoumarin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125251,CAS号为 23660-05-1。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0775 |
Coumarin
|
Factor Xa; Influenza Virus | Metabolism; Microbiology/Virology |
Coumarin 是中国北沙参中的一种主要生物活性成分,具有抗癌、抗炎和抗病毒等活性。它作为几种抗凝剂的前体具有临床价值,尤其是华法林。 | |||
TN1529 |
Coumarin 6
Coumarin VI,香豆素 6 |
Others | Others |
Coumarin 6 (Coumarin VI) 是一种荧光染料,可作为微粒给药系统中的荧光探针,研究药物给药系统的体内跟踪、细胞摄取和转运机制。 | |||
T7960 |
Coumarin 7
香豆素-7,香豆素7 |
Others | Others |
Coumarin 7 是一种在植物中以糖苷的形式存在的香豆素激光染料。 | |||
TJS0341 |
7-Amino-4-(trifluoromethyl)coumarin
香豆素151,Coumarin 151,AFC,7-氨基-4-(三氟甲基)香豆素 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物,其激发和发射波长分别为400和500 nm,可用来灵敏的检测蛋白酶。 | |||
TJS0339 |
Coumarin-3-carboxylic acid
香豆素-3-羧酸,3-Carboxycoumarin |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Coumarin-3-carboxylic acid (3-Carboxycoumarin) 是一种合成香豆素的重要起始化合物。其中香豆素是具有多种生物活性的天然产物。它的镧系复合物对 K-562 细胞具有抗增殖活性。 | |||
TN1243 |
3-Aminocoumarin
3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine |
Others | Others |
3-Aminocoumarin (3-aminochromen-2-one) 是金属配合物的关键中间体。 | |||
T2909 |
Fraxetin
7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀 |
Apoptosis; Others | Apoptosis; Others |
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) 是从秦皮中分离出来的一种天然产物,可诱导细胞凋亡,具有抗肿瘤、抗氧化作用和抗炎作用。 | |||
TN6209 |
7-(3'-Carboxybutoxy)coumarin
|
||
7-(3'-Carboxybutoxy)coumarin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6209,CAS号为 16851-01-7。 | |||
TJS0311 |
Ethyl 3-coumarincarboxylate
3-Ethoxycarbonylcoumarin,香豆素-3-羧酸乙酯,香豆素-3-羧酸乙素,Ethyl 2-Oxo-2H-Chromene-3-Carboxylate,Ethyl coumarin-3-carboxylate,3-Carbethoxycoumarin |
Others | Others |
Ethyl coumarin-3-carboxylate 是香豆素衍生物。它可作为一种伪模板,制备能够特异性识别黄曲霉毒素的分子印迹聚合物 (MIP)。 | |||
TN2024 |
Oxyimperatorin
|
Others | Others |
Oxyimperatorin 是一种香豆素,分离自当归。 | |||
TN6207 | 7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin | ||
7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6207,CAS号为 118584-19-3。 | |||
T37345 |
5,7-Dihydroxycoumarin
|
Antibacterial | Microbiology/Virology |
5,7-Dihydroxycoumarin 是分离自Macaranga triloba 花序的香豆素,具有抗菌活性。 | |||
TN1120 |
Osthenol
|
MAO; Monoamine Oxidase | Metabolism; Neuroscience |
Osthenol 是一种前酰化香豆素,从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用,IC50=0.74 µM,对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的,选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。 | |||
T7934 |
7-Methylcoumarin
|
Others | Others |
7-Methylcoumarin 具有很强的保肝活性。 | |||
TN5888 |
Toddaculin
|
Others | Others |
Toddaculin 是一种天然香豆素,抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡,具有抗炎活性。 | |||
T6S1435 |
Notopterol
|
Apoptosis; Others | Apoptosis; Others |
Notopterol 是从羌活提取的一种香豆素,可诱导细胞凋亡,具有解热、缓解疼痛和抗炎作用。它有用于急性髓细胞性白血病的潜力。 | |||
T8002 |
3-Hydroxycoumarin
|
Lipoxygenase | Metabolism |
3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂,近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。 | |||
T8038 |
7-Ethoxy-4-Methylcoumarin
|
Others | Others |
7-Ethoxy-4-Methylcoumarin 具有独特气味的芳香化合物。它被认为是细胞中酶的抑制剂,已被用于酶抑制的研究,并已被用于研究各种药物对人体的影响。 | |||
T3872 |
Nodakenin
紫花前胡苷,(+)-Marmesinin |
AChE | Neuroscience |
Nodakenin ((+)-Marmesinin) 是一种Peucedanum decursivum Maxim 根中的主要香豆素苷。它能够抑制乙酰胆碱酯酶活性,IC50=84.7 μM。 | |||
T3888 |
Scopolin
Murrayin,东莨菪甙,Scopoloside,东莨菪苷 |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Scopolin (Scopoloside) 是从拟南芥根中分离出来的香豆素,可通过激活SIRT1介导的信号级联反应减轻了肝脂肪变性。 | |||
T4S0592 |
Toddalolactone
(+)-Toddalolactone,飞龙掌血内酯,毛两面针素 |
PAI-1 | Metabolism |
Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分,能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性, IC50=37.31 μM。 | |||
TN1328 |
7-Amino-4-methylcoumarin-3-acetic acid
7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin |
Others | Others |
7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) 是荧光蛋白质标记剂,能够被紫外光(350 nm) 激活,可在蓝色区域 (440-460 nm) 发光。 | |||
TJS0328 |
Nordalbergin
6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素 |
Others | Others |
Nordalbergin 是一种香豆素,分离自Dalbergia sissoo 的木皮中。 它能够显著性的诱导 HL-60 细胞的分化。 | |||
TJS0312 |
7-hydroxy-4-methyl-8-nitrocoumarin
|
Others | Others |
7-Hydroxy-4-methyl-8-nitrocoumarin 是香豆素衍生物的一种。 | |||
T5647 |
6-Methylcoumarin
Toncarine,6-甲基香豆素 |
Others | Others |
6-Methylcoumarin (Toncarine) 是一种合成香料,广泛用于化妆品中。 | |||
TJS0318 |
6-Hydroxy-4-methylcoumarin
6-羟基-4-甲基香豆素,6-Hydroxy-4-Methyl-2H-Chromen-2-One,6-羟基-4-甲基香豆素;6-羟基-4-甲基-2H-1-苯并吡喃-2-酮 |
Others | Others |
6-Hydroxy-4-methylcoumarin (6-Hydroxy-4-Methyl-2H-Chromen-2-One) 是一种香豆素的次级代谢产物,具有抗癌作用。 | |||
PDK0015 |
4-Hydroxycoumarin
|
Endogenous Metabolite; Antibacterial; AChR | Metabolism; Microbiology/Virology; Neuroscience |
4-Hydroxycoumarin 是香豆素衍生物,也是通用的杂环支架之一,具有亲电和亲核性质。 | |||
Fr12277 |
4-Hydroxy-6-methylcoumarin
|
Others | Others |
4-Hydroxy-6-methylcoumarin(4-HMC)是一种天然存在的酚类化合物,是香豆素的衍生物,存在于各种植物、真菌和细菌中,具有抗炎和抗肿瘤活性。4-HMC 在食品工业中用作调味剂、防腐剂和抗氧化剂。 | |||
T4137 |
4,7-DIHYDROXYCOUMARIN
|
Others | Others |
4,7-DIHYDROXYCOUMARIN 是一种天然存在的香豆素衍生物,存在于多种植物中,包括欧芹和洋甘菊。已经发现它可以抑制几种酶的活性,包括细胞色素P450、环氧合酶和脂氧合酶;也可以与DNA 结合,调节基因表达,并抑制细胞周期进展;还可以诱导肿瘤细胞凋亡并减轻炎症。 | |||
TN1552 |
7,8-Dimethoxycoumarin
7,8-dimethoxychromen-2-one,Daphnetin dimethyl ether |
Others | Others |
7,8-Dimethoxycoumarin 是一种从 Artemisia caruifolia 和 Wikstroemia indica 中分离出来的天然产物。 | |||
T7993 |
8-Acetyl-7-Hydroxycoumarin
|
Antifungal | Microbiology/Virology |
8-Acetyl-7-Hydroxycoumarin 是一种天然化合物,具有抗真菌和抗菌活性。 | |||
T2S0357 |
6-Hydroxycoumarin
6-hydroxychromen-2-one,6-羟基香豆素 |
Others; Carbonic Anhydrase | Metabolism; Others |
6-Hydroxycoumarin (6-hydroxychromen-2-one) 是一种香豆素。其中香豆素具有抗炎,支气管扩张,解热,血管扩张,抗氧化,抗菌,抗真菌,抑菌和抗肿瘤作用。 | |||
TJS0314 |
5,7-Dihydroxy-4-methylcoumarin
Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin |
Others; Antibacterial; Antifungal | Microbiology/Virology; Others |
5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) 是墨西哥龙蒿中的一种香豆素衍生物。它抑制人类中性粒细胞氧化代谢和弹性蛋白酶活性,有抗真菌和抗细菌活性。 | |||
T5744 |
7-Prenyloxycoumarin
7-(异戊烯基氧基)香豆素,Nsc267697,7-O-Prenylumbelliferone,7-异戊烯氧基香豆素 |
Antifungal | Microbiology/Virology |
7-Prenyloxycoumarin (Nsc267697) 是一种 Heracleum dissectum 的天然产物,对乳腺癌具有预防和治疗作用。 | |||
Fr12596 |
3-Acetylcoumarin
|
Others | Others |
3-Acetylcoumarin 作为室温下铜催化 CN 偶联反应的实用配体。它具有神经保护和杀螨特性。 | |||
Fr12290 |
4-Methoxycoumarine
|
Others | Others |
4-Methoxycoumarine 具有抗肿瘤作用。 | |||
Fr12662 |
4-Ethoxycoumarin
|
Others | Others |
4-Ethoxycoumarin 具有抗菌活性。 | |||
T7970 |
7-Ethoxycoumarin
|
Others | Others |
7-Ethoxycoumarin 是细胞色素 P450(CYP) 的底物,现已被应用于多种 CYP 的功能表征。 | |||
TN1702 |
Glycycoumarin
甘草香豆素 |
P450; JNK; AMPK; Autophagy | Autophagy; Chromatin/Epigenetic; MAPK; Metabolism; PI3K/Akt/mTOR signaling |
Glycycoumarin 是甘草中的一种香豆素,能直接靶向 T-LAK 细胞源蛋白激酶发挥抗肝癌活性 。它通过激活自噬,抑制内质网应激介导的 JNK 和 GSK-3 介导的线粒体途径,来抑制肝细胞脂性凋亡。它是一种雌激素激动剂,对 CYP1A2 和 CYP2B6 有中度抑制作用。 | |||
T2S0300 |
Dihydrocoumarin
二氢香豆素,Chroman-2-one,Hydrocoumarin,melilotin,2-chromanone,3,4-dihydrocoumarin,二氢香豆素;氢化肉桂酸内酯、1,2-苯并二氢吡喃酮、二氢色满酮、二羟基香豆素;苯并二氢吡喃酮;二氢香豆酯、二氢香兰素 |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Dihydrocoumarin (melilotin) 是在草木犀中发现的一种天然产物。它是酵母 Sir2p 抑制剂,还抑制人 SIRT1和SIRT2,IC50分别为 208 和 295 μM。 | |||
TN3110 |
5-Geranoxy-7-methoxycoumarin
|
Anti-infection; Antibacterial; Antifungal | Microbiology/Virology |
5-Geranoxy-7-methoxycoumarin 是一种香豆素。它诱导细胞凋亡,具有抗癌、抗真菌和抗菌活性。 | |||
T8113 |
4-Methyl-6-Methoxycoumarin
|
Others | Others |
4-Methyl-6-Methoxycoumarin 是一种从 Eupatorium pauciflorum 中分离出来的天然产物。 | |||
TJP2865 |
7-methoxy-8-hydroxy-4-methylcoumarin
|
Others | Others |
7-methoxy-8-hydroxy-4-methylcoumarin 是分离自酸橙 (Citrus aurantium) 的一种化合物。 | |||
TJS0368 |
4-Phenyl-7,8-dihydroxycoumarin
7,8-二羟基-4-苯基香豆素,7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin |
Others | Others |
4-Phenyl-7,8-dihydroxycoumarin (7,8-Dihydroxy-4-phenylcoumarin) 是香豆素衍生物,可用于研究支气管扩张。 | |||
T81334 |
Qianhucoumarin B
|
||
Qianhucoumarin B, 香豆素类衍生物,源自中药Peucedanum praeruptorum根部提取。 | |||
T81333 | Qianhucoumarin C | ||
Qianhucoumarin C是从白前胡(Peucedanum praeruptorum)根部提取的香豆素类化合物,已研究其具有抗炎、抗氧化和抗癌等潜在药用活性。Qianhucoumarin C亦在多个工业流程中发挥重要作用,尤其是在制药和草药制造过程中。 | |||
T11683 |
Isoglycycoumarin
|
Others | Others |
Isoglycycoumarin, a flavonoid derived from the roots of Glycyrrhiza uralensis, serves as a highly selective probe for human cytochrome P450 2A6. | |||
TN4880 |
Qianhucoumarin A
|
Others | Others |
Qianhucoumarin A是一种天然产物,属于伞形科前胡属,其产品编号为 TN4880,CAS号为 150135-35-6。Qianhucoumarin A可用作对照参考。 | |||
TN3271 |
8-Acetyl-7-methoxycoumarin
|
Others | Others |
8-Acetyl-7-methoxycoumarin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3271,CAS号为 89019-07-8。 | |||
T82966 | Arnocoumarin | ||
Arnocoumarin为自X. arnottianum MAXIM分离出的天然化合物。 | |||
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