Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Geranoxy-7-methoxycoumarin 是一种香豆素。它诱导细胞凋亡,具有抗癌、抗真菌和抗菌活性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 628 | 现货 | ||
5 mg | ¥ 1,530 | 现货 | ||
10 mg | ¥ 2,280 | 现货 | ||
25 mg | ¥ 3,860 | 现货 | ||
50 mg | ¥ 5,530 | 现货 | ||
100 mg | ¥ 7,730 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,620 | 现货 |
产品描述 | 5-Geranoxy-7-methoxycoumarin shows antifungal activity. |
体外活性 | Two mechanisms of the resistance of citrus fruits against pathogens-preformed and induced antifungal materials-were investigated. METHODS AND RESULTS: Flavedo tissue of lemon contains the following preformed antifungal materials: citral, limettin, 5-Geranoxy-7-methoxycoumarin, and isopimpinellin, which act as the first line of defense against pathogens. Exogenous application of citral to Penicillium-inoculated lemon fruit prevented development of decay. Being subjected to fungal challenge and/or abiotic stress, citrus fruits are elicited to produce the phytoalexin scoparone, considered as another line of fruit defense. According to median effective dose (ED50) of the inhibition of germ-tube elongation or percent germination, scoparone had higher fungitoxicity against Penicillium digitatum Sacc. than the preformed antifungal materials. Different citrus species (lemon, orange, grapefruit, lime, kumquat) varied in their capacities to produce scoparone responding to the combined Penicillium inoculation and heat treatment or to UV illumination. UV illumination of lemon fruit reduced its susceptibility to P. digitatum. CONCLUSIONS: Expression of this effect was directly related to the level of scoparone in illuminated fruit. UV light and citral application were visibly injurious to the flavedo tissues in high dose. |
分子量 | 328.4 |
分子式 | C20H24O4 |
CAS No. | 7380-39-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.28 mg/mL (10 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.0451 mL | 15.2253 mL | 30.4507 mL | 76.1267 mL |
5 mM | 0.609 mL | 3.0451 mL | 6.0901 mL | 15.2253 mL | |
10 mM | 0.3045 mL | 1.5225 mL | 3.0451 mL | 7.6127 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
5-Geranoxy-7-methoxycoumarin 7380-39-4 Microbiology/Virology Anti-infection Antibacterial Antifungal Apoptosis 5 Geranoxy 7 methoxycoumarin Bacterial Fungal antifungal inhibit DNA fragmentation 5Geranoxy7methoxycoumarin Inhibitor inhibitor