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104

抑制剂 & 化合物

32

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0274	Cinoxacin 西诺沙星,Compound 64716	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Cinoxacin (Compound 64716) 是一种喹诺酮类的合成抗生素, 与Oxolinic acid 和 Nalidixic acid 活性相似。
T0495	Aminothiazole 2-Aminothiazole,2-氨基噻唑,2-Thiazolylamine,氨噻唑	Virus Protease; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Aminothiazole (2-Aminothiazole) 是一种甲状腺抑制剂，具有抗菌活性。它是一种典型的杂环胺，是合成多种生物活性分子的前体，包括染料，抗生素，硫磺药物，杀真菌剂和化学反应促进剂。
T38476	Metallo β-lactamase ligand 1	Antibacterial	Microbiology/Virology
	Metallo β-lactamase ligand 1 是B 类β-内酰胺酶的抑制剂，具有抗菌活性。
T16269	Nanaomycin A	DNA Methyltransferase; Dehydrogenase; Parasite	Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Nanaomycin A 是一种醌类抗生素，可重新激活人类癌细胞中沉默的肿瘤抑制基因。 Nanaomycin A 是 DNMT3B 的特异性抑制剂 (IC50 = 500 nM)。
T3657	Dcimc chloride 3-(2,6-二氯苯基)-5-甲基异唑-4-甲酰氯,3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride	Antibiotic	Microbiology/Virology
	Dcimc chloride (3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride) 具有抗生素活性。
T11265	Faropenem daloxate 法罗培南酯,Faropenem medoxil	Antibacterial; Antibiotic	Microbiology/Virology
	Faropenem daloxate (Faropenem medoxil) 是β-内酰胺类口服抗生素。
T32008	GSK299423 GSK-299423,GSK 299423
	GSK299423 (GlaxoSmithKline 299423) is an antibiotic that may have therapeutic effect in patients infected with bacteria expressing New Delhi metal-β-lactamase. Antibiotics inhibit the topoisomerases that the bacteria need to replicate.
T13303	Virginiamycin M1 Pristinamycin IIA,Ostreogrycin A	Antibacterial	Microbiology/Virology
	Virginiamycin M1 (Pristinamycin IIA)是一种大环内酯肽类抗生素，是链菌素a 类抗生素的成员。
T0049	Azlocillin sodium salt Sodium azlocillin,Azlocillin sodium,阿洛西林钠	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Azlocillin sodium salt 是一种半合成青霉素，是内酰胺类广谱抗生素。它具有抗假单胞杆菌的活性，并对抗寄生虫Plasmodium falciparum 有效。
T2469	TP808 TP-808,TP 808	Others	Others
	TP808是一种高度通用的中间体，可用于多种四环素类抗生素的构建。
T12481	Pipecuronium bromide RGH-1106	AChR	Neuroscience
	Pipecuronium bromide (RGH-1106)是一种具有选择性和有效性的 nAChR 拮抗剂，也可当作一种非去极化甾体神经肌肉阻滞剂，可使肌肉松弛，常与抗生素一起使用。
T2096	Framycetin sulfate Neomycin Sulphate B,硫酸新霉素B,Framycetin sulphate	Antibacterial; Antibiotic	Microbiology/Virology
	Framycetin sulfate (Neomycin Sulphate B) 是一种氨基糖苷类抗生素，是 RNase P 裂解活性抑制剂，Ki 为 35 μM。它抑制锤头状核酶，Ki 值为 13.5 μM，可用于肝性脑病和肠致病性大肠杆菌感染的研究。
T1372	2-Methoxybenzylamine	Others	Others
	2-Methoxybenzylamine 广泛用于合成其他化合物，如染料、香料和塑料；还可以用于合成生物活性化合物，如抗生素和抗真菌剂。
TP1329	Nisin	Antibacterial; Antibiotic	Microbiology/Virology
	Nisin 是乳酸链球菌肽，由一组属于乳球菌和链球菌属的革兰氏阳性菌产生。
T3125	Amikacin sulfate Amikacin Sulfate Salt,阿米卡霉素硫酸,硫酸阿米卡星	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Amikacin sulfate 是一种氨基糖苷类抗生素，也是卡那霉素的半合成类似物。它具有杀菌作用，直接作用于 30S 和 50S 细菌核糖体亚基，可抑制蛋白质合成。它抑制大多数革兰氏阴性细菌，还抑制易感诺卡氏菌和非结核分枝杆菌引起的感染。
T124492	Imipenem N-Formimidoyl thienamycin,MK0787	Antifungal	Microbiology/Virology
	Imipenem (MK0787) 是一种噻吩霉素衍生物，属于抗生素类，具有抗菌活性，对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。
T12992	SPR741 acetate SPR741 acetate,NAB741 acetate,SPR741 acetate (1179330-52-9 free base)	Antibacterial	Microbiology/Virology
	SPR741 acetate 是衍生自多粘菌素 B 的阳离子肽，通过增加革兰氏阴性细菌外膜的通透性来抑制严重的革兰氏阴性细菌感从而展现出对革兰氏阴性菌的抗菌活性。SPR741 acetate 常与抗生素联合使用来治疗一些疾病。
T1631	Sulbactam CP45899,舒巴坦,舒巴坦酸	Antibacterial; Antibiotic	Microbiology/Virology
	Sulbactam (CP45899) 是一种竞争性、不可逆的 β-内酰胺酶抑制剂，抑制耐多药不动杆菌-鲍曼不动杆菌复合物。它具有抗菌活性。
T4165	Delpazolid LCB01-0371	Antibacterial; Antibiotic	Microbiology/Virology
	Delpazolid (LCB01-0371) 是一种恶唑烷酮类新型抗生素，能抑制MSSA 和MRSA 的生长，对它们的MIC90值都为 2 μg/mL。
T0983L	DL-Penicillamine 3-Sulfanylvaline,DL-青霉胺	Antibiotic	Microbiology/Virology
	DL-Penicillamine (3-Sulfanylvaline) 是一种螯合剂，推荐用于去除威尔逊病患者体内多余的铜。它仅存在于使用或服用该药物的个体中。它是青霉素类抗生素最具特征的降解产物。它被用作抗风湿药和威尔逊病的螯合剂。
TP2285	Quinupristin-Dalfopristin Complex (mesylate)	Others	Others
	Quinupristin-Dalfopristin Complex is a mixture of two streptogramin antibiotics. Quinupristin-dalfopristin complex is a mixture of two streptogramin antibiotics, dalfopristin, and quinupristin. Streptogramin antibiotics are divided into types A and B, whi
T24246	Kapurimycin A2
	Kapurimycin A2 is an antitumor antibiotics.
T26249	TANDEM (quinoxaline) Tandem
	TANDEM (quinoxaline) is a synthetic analog of antibiotics quinoxaline.
T26153	RU 44790 RU-44790,RU44790
	RU 44790 is a synthetic monocyclic beta-lactam antibiotics.
T34270	Razupenem SMP601,SMP 601,PTZ601,PTZ 601,PTZ-601,SMP-601
	Razupenem ( SMP-601, PTZ601) is a broad-spectrum injectable antibiotic derived from the carbapenem subgroup of β-lactam antibiotics. It has been developed as an alternative drug against bacteria that have developed antibiotic resistance to commonly used a
T11000	Descarbamoyl cefuroxime	Others	Others
	Descarbamoyl cefuroxime is also an intermediate in the synthesis of cephalosporin antibiotics. Decarbamyl cefuroxime is a degradation product of cefuroxime.
T28541	Ritipenem Acoxil Ritipenem acetoxymethyl ester,RIPM-AC
	Ritipenem Acoxil is an antibiotics.
T24247	Kapurimycin A3 Kaphamycin,Kafamycin,Caphamycin
	Kapurimycin A3 is an antitumor antibiotics.
T25587	Kujimycin A Desacetyllankamycin
	Kujimycin A is a macrolide antibiotics agent from various strains of Streptomyces. It has great activity against some Gram-positive bacteria.
T0149	Pheneticillin	Others	Others
	Pheneticillin 是一种具有抗菌性的抗生素。
T26129	RPR 102341 RPR-102341,RPR102341
	RPR 102341 is an antibiotics. It is a benzonaphthydridone, active against both gram-positive and negative bacteria.
T27962	Ancremonam LYS228,LYS-228,LYS 228
	LYS228 is a potent antibiotics against Carbapenem-Resistant Enterobacteriaceae (MIC90 = 2 uM/mL). LYS228 is potent in the presence of all classes of beta-lactamases.
T26185	Septacidin NSC-65104,NSC65104,NSC 65104
	Septacidin represents a group of l-eptopyranoses including nucleoside antibiotics with antitumor, antifungal, and pain-relief activities.
T25183	Bulgecin C
	Bulgecin C is an O-sulfonated glycopeptides that can enhance the antibacterial activity of beta-lactam antibiotics.
T26461	A-10255 A 10255
	A-10255 is a complex of thiopeptide antibiotics from Streptomyces gardneri.
T23957	Dactylocycline B
	Dactylocyclines B is a novel tetracycline derivative produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp.
T25013	Aklanonic acid
	Aklanonic acid is an intermediate in the biosynthesis of anthracycline antibiotics from Streptomyces sp. ZIMET 43717.
T23952L	Dactimicin sulfate SF-2052 sulfate,Antibiotic SF 2052 sulfate
	Dactimicin is a new aminoglycoside. It also has in vitro activity, post-antibiotic effect, and interaction with other antibiotics.
T26465	A1-226 A1226
	A1-226 is a cephalosporin of the class of β-lactam antibiotics, it is originally derived from the fungus Acremonium.
T28436	Polyoxin B Polyoxin-B
	Polyoxin B is a nucleoside antibiotics composed of heterocyclic moieties containing nitrogen. Polyoxin B inhibits the biosynthesis of chitin.
T28288	Pacidamycin I A-68567,A 68567,A68567
	Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly.
T40906	2-Nitrosopyridine
	2-Nitrosopyridine is a versatile nitroso compound employed in the synthesis of antibiotics. It serves as a valuable derivatization reagent for Click and Diels-Alder reactions, displaying exceptional dienophile characteristics.
T24992	A-130A Antibiotic A 130A,A 130A,Antibiotic Ro 21 6150,Lenoremycin
	A-130A is a polycyclic polyether compound belonging to the nigericin group of antibiotics generated by Streptomyces hygroscopicus strain.
T39811	D-4-Hydroxyphenylglycine 4-Hydroxy-D-phenylglycine,D-(-)-4-Hydroxyphenylglycine,D-4-Hydroxyphenylglycine
	D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is a crucial raw material in the synthesis of semisynthetic β-lactam antibiotics, including Amoxicillin and Cefadroxil .
T23956	Dactylocycline A
	Dactylocyclines A is novel tetracycline derivatives produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp.
T34740	Sulfacytine Renoquid,CI636,CI-636,CI 636,磺胺西汀,Sulfacitinum
	Sulfacytine is a short-acting sulfonamides antibiotic that is taken orally to treat bacterial infections. Sulfonamides, a group of antibiotics, work by inhibiting bacterial production of folic acid.
T25844	N4Py N-4-Py,N 4 Py
	N4Py is a good synthetic mimic of the Bleomycins (BLMs), which are a family of natural antibiotics used clinically in the treatment of certain cancers.
T23955	Dactylfungin B
	Dactylfungins B is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
T23954	Dactylfungin A
	Dactylfungins A is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
T68866	Ceftolozane
	Ceftolozane, also known as FR-264,205 and CXA-101; is an antibiotic drug from the cephalosporin family, approved for the treatment of infections with gram-negative bacteria, or gram-positive bacteria. Ceftolozane is of great benefit due to its ability to target bacteria that have become resistant to conventional antibiotics. Ceftolozane is combined with the β-lactamase inhibitor tazobactam, as multi-drug resistant bacterial infections will generally show resistance to all β-lactam antibiotics un...

化合物

Cat.No: T0274

Synonym: 西诺沙星,Compound 64716

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0495

Synonym: 2-Aminothiazole,2-氨基噻唑,2-Thiazolylamine,氨噻唑

Target: Virus Protease, Antibacterial, Antibiotic, Antifungal

Metallo β-lactamase ligand 1

Cat.No: T38476

Target: Antibacterial

Cat.No: T16269

Target: DNA Methyltransferase, Dehydrogenase, Parasite

Cat.No: T3657

Synonym: 3-(2,6-二氯苯基)-5-甲基异唑-4-甲酰氯,3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride

Target: Antibiotic

Faropenem daloxate

Cat.No: T11265

Synonym: 法罗培南酯,Faropenem medoxil

Target: Antibacterial, Antibiotic

Cat.No: T32008

Synonym: GSK-299423,GSK 299423

Virginiamycin M1

Cat.No: T13303

Synonym: Pristinamycin IIA,Ostreogrycin A

Target: Antibacterial

Azlocillin sodium salt

Cat.No: T0049

Synonym: Sodium azlocillin,Azlocillin sodium,阿洛西林钠

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T2469

Synonym: TP-808,TP 808

Target: Others

Pipecuronium bromide

Cat.No: T12481

Synonym: RGH-1106

Target: AChR

Framycetin sulfate

Cat.No: T2096

Synonym: Neomycin Sulphate B,硫酸新霉素B,Framycetin sulphate

Target: Antibacterial, Antibiotic

2-Methoxybenzylamine

Cat.No: T1372

Target: Others

Cat.No: TP1329

Target: Antibacterial, Antibiotic

Amikacin sulfate

Cat.No: T3125

Synonym: Amikacin Sulfate Salt,阿米卡霉素硫酸,硫酸阿米卡星

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T124492

Synonym: N-Formimidoyl thienamycin,MK0787

Target: Antifungal

Cat.No: T12992

Synonym: SPR741 acetate,NAB741 acetate,SPR741 acetate (1179330-52-9 free base)

Target: Antibacterial

Cat.No: T1631

Synonym: CP45899,舒巴坦,舒巴坦酸

Target: Antibacterial, Antibiotic

Cat.No: T4165

Synonym: LCB01-0371

Target: Antibacterial, Antibiotic

DL-Penicillamine

Cat.No: T0983L

Synonym: 3-Sulfanylvaline,DL-青霉胺

Target: Antibiotic

Quinupristin-Dalfopristin Complex (mesylate)

Cat.No: TP2285

Target: Others

Cat.No: T24246

TANDEM (quinoxaline)

Cat.No: T26249

Synonym: Tandem

Cat.No: T26153

Synonym: RU-44790,RU44790

Cat.No: T34270

Synonym: SMP601,SMP 601,PTZ601,PTZ 601,PTZ-601,SMP-601

Descarbamoyl cefuroxime

Cat.No: T11000

Target: Others

Ritipenem Acoxil

Cat.No: T28541

Synonym: Ritipenem acetoxymethyl ester,RIPM-AC

Cat.No: T24247

Synonym: Kaphamycin,Kafamycin,Caphamycin

Cat.No: T25587

Synonym: Desacetyllankamycin

Cat.No: T0149

Target: Others

Cat.No: T26129

Synonym: RPR-102341,RPR102341

Cat.No: T27962

Synonym: LYS228,LYS-228,LYS 228

Cat.No: T26185

Synonym: NSC-65104,NSC65104,NSC 65104

Cat.No: T25183

Cat.No: T26461

Synonym: A 10255

Dactylocycline B

Cat.No: T23957

Cat.No: T25013

Dactimicin sulfate

Cat.No: T23952L

Synonym: SF-2052 sulfate,Antibiotic SF 2052 sulfate

Cat.No: T26465

Synonym: A1226

Cat.No: T28436

Synonym: Polyoxin-B

Cat.No: T28288

Synonym: A-68567,A 68567,A68567

2-Nitrosopyridine

Cat.No: T40906

Cat.No: T24992

Synonym: Antibiotic A 130A,A 130A,Antibiotic Ro 21 6150,Lenoremycin

D-4-Hydroxyphenylglycine

Cat.No: T39811

Synonym: 4-Hydroxy-D-phenylglycine,D-(-)-4-Hydroxyphenylglycine,D-4-Hydroxyphenylglycine

Dactylocycline A

Cat.No: T23956

Cat.No: T34740

Synonym: Renoquid,CI636,CI-636,CI 636,磺胺西汀,Sulfacitinum

Cat.No: T25844

Synonym: N-4-Py,N 4 Py

Cat.No: T23955

Cat.No: T23954

Cat.No: T68866

Cat. No.	Product Name	Target	Signaling Pathways
T41044	Naringinase	Glucosidase	Metabolism
	Naringinase 是一种在自然界中广泛存在的水解酶复合物，具有 α-L-鼠李糖苷酶和 β-D-葡萄糖苷酶的活性，主要用于糖苷的水解。
T8347	Rifamycin S	Reactive Oxygen Species; ROS; Antibacterial; Antibiotic	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Rifamycin S 是一种 DNA 依赖性 RNA 聚合酶抑制剂，是一种醌和一种针对革兰氏阳性细菌的抗生素试剂。它是涉及两个电子的可逆氧化还原系统的氧化形式。它能产生活性氧并抑制微粒体脂质过氧化，可研究肺结核和麻风病。
T0989	7-Aminocephalosporanic acid 7-氨基头孢烷酸,7-ACA	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	7-Aminocephalosporanic acid (7-ACA) 用于合成头孢菌素类抗生素及其中间体。
T21498	Phleomycin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Phleomycin 是在链霉菌中发现的，引起 DNA 切割的抗癌糖肽抗生素之一。它类似于博来霉素，它结合并插入 DNA 以破坏双螺旋的完整性。
TN2943	3-Hydroxy-6-methoxyflavone	Others	Others
	3-Hydroxy-6-methoxyflavone 可与抗生素联合用药来治疗 ESKAPE 病原体感染。
TN1493	Chrysosplenol D 猫眼草酚D	IL Receptor; NF-κB; JNK	Immunology/Inflammation; MAPK; NF-κB
	Chrysosplenol D 属于甲氧基黄酮类化合物，可诱导 ERK1/2 介导的三阴性人乳腺癌细胞凋亡。它还显示出抗炎和中等抗锥虫活性。
T1687L	Doxycycline (hyclate) Doxycycline hydrochloride hemiethanolate hemihydrate,盐酸强力霉素,WC2031,Doxycycline hyclate	MMP; ribosome; Antibacterial; Antibiotic	Microbiology/Virology; Proteases/Proteasome
	Doxycycline hyclate (WC2031) 属于四环素类抗生素，是一种广谱的金属蛋白酶 (MMP) 抑制剂，具有口服活性。Doxycycline hyclate 具有抗菌活性和抗肿瘤活性。
T7335	2,3-Diaminopropionic acid L-2,3-二氨基丙酸,L-2,3-Diaminopropionic acid	Endogenous Metabolite	Metabolism
	2,3-Diaminopropionic acid (L-2,3-Diaminopropionic acid) 是一种神经毒性氨基酸 b-oxalyl-L-a, b-diaminopropionic acid 的代谢产物。
T1687	Doxycycline Vibramycin,多西环素,Doxiciclina,Doxytetracycline,Doxycyclinum,强力霉素	MMP; ribosome; Antibacterial; Antibiotic; Parasite	Microbiology/Virology; Proteases/Proteasome
	Doxycycline (Doxiciclina) 属于四环素类抗生素，是一种广谱的金属蛋白酶 (MMP) 抑制剂，具有口服活性。Doxycycline 具有抗菌活性和抗肿瘤活性。
T13229	Tunicamycin	Influenza Virus; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Tunicamycin 是一种抗生素的混合物，通过阻断 GlcNAc 磷酸转移酶 (GPT)，抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性，还具有抗细菌、抗真菌和抗病毒活性。
T0814L	Ampicillin Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid	Antibacterial; Antibiotic	Microbiology/Virology
	Ampicillin (Aminobenzylpenicillin) 属于 β-内酰胺类抗生素，是一种半合成的青霉素。Ampicillin 具有杀菌活性，对各种革兰氏阳性细菌和革兰氏阴性细菌均有抑制活性。
T1130	Gramicidin 短杆菌肽,Gramicidinum,Gramicidine,Gramicidina	MRP; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology
	Gramicidin (Gramicidine) 是一种抗菌肽。它通过组装成膜中的通道，增加其对阳离子的渗透性。
T6062	Brefeldin A BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin	ATPase; Mitophagy; Antibiotic; Autophagy; HSV; CRISPR/Cas9	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Brefeldin A (Cyanein) 属于大环内酯类抗生素，是一种 ATPase 抑制剂 (IC50=0.2 μM)。Brefeldin A 可以诱导肿瘤细胞分化和凋亡，也具有抑制自噬的活性。
T1219	Sisomicin Sulfate 硫酸西索米星,Pathomycin,Extramycin,硫酸西索紫苏	Antibacterial; Antibiotic	Microbiology/Virology
	Sisomicin Sulfate (Pathomycin) 是由Micromonospora inyoensis 产生的一种广谱氨基糖苷类抗生素，对革兰氏阳性细菌有很大活性。
T8641	Vancomycin	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Vancomycin 是一种糖肽类抗生素，可以通过改变细胞膜的渗透性并选择性地抑制核糖核酸的合成以发挥抗菌活性。Vancomycin 可以用于治疗所有抗生素均无效的严重感染。
T0983	Penicillamine 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine	Antibiotic	Microbiology/Virology
	Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
T15245	Erythromycin estolate Phtalic anhydride,ilosone	Antibacterial	Microbiology/Virology
	Erythromycin estolate 是红霉素的衍生物，属于大环内酯类抗生素，常用于研究多种细菌感染。酯酸红霉素对胆汁酸转运有抑制作用，可引起肝损伤，主要是胆汁淤积性肝炎。
T6740	Bafilomycin A1 巴佛洛霉素A1,巴佛洛霉素 A1	Apoptosis; Proton pump; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
	Bafilomycin A1 属于大环内酯类抗生素，是一种 V-ATPase (IC50=0.44 nM)，具有特异性和可逆性。Bafilomycin A1 是自噬晚期阶段抑制剂，阻断自噬体与溶酶体的融合。Bafilomycin A1 也诱导凋亡。
T7988	3,4-Diaminotoluene	Others	Others
	3,4-Diaminotoluene 是一种从甲苯中提取的芳香胺，已用于合成各种化合物，如聚氨酯、聚脲和聚酰胺，以及合成氨基酸、肽和蛋白质，它还被用于合成各种药物，如抗生素和抗病毒药物。
T1020	Doxorubicin hydrochloride Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,盐酸多柔比星,盐酸阿霉素,NSC 123127	Apoptosis; Mitophagy; HBV; HIV Protease; Topoisomerase; Antibacterial; Antibiotic; AMPK; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Doxorubicin hydrochloride (Adriamycin) 属于蒽环类抗生素，是人类 DNA 拓扑异构酶 I/II 抑制剂 (IC50=0.8/2.67 μM)。Doxorubicin hydrochloride 具有细胞毒性和抗肿瘤活性。Doxorubicin hydrochloride 可降低 AMPK 及其下游靶蛋白乙酰辅酶 A 羧化酶的磷酸化，还可诱导凋亡和自噬。
T65269	L-Aspartic acid potasium salt Aspartic acid potasium salt,Potassium L-aspartate	Others	Others
	L-aspartic acid potasium salt（VX-548）是一种广泛存在于动植物体内的氨基酸。L-aspartic acid potasium salt驱动氮氧化物的产生，从而促进吞噬作用，有助于提高鱼类的成活率。L-aspartic acid potasium salt 可对抗生素产生刺激，刺激作用可能与参与天冬氨酸-4-半醛生物合成的前体有关。
T24000	Dihydrocarminomycin Dihydrokarminomycin,Carminomycinol,RP-32999
	Dihydrocarminomycin is an anthracycline antibiotics.
TN4319	Isopimaric acid	Antifection	Microbiology/Virology
	Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . Isopimaric acid is also possible that an antagonistic interacti
TN4725	Oxychelerythrine	Antifection	Microbiology/Virology
	Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 192.32 p
T73954	Leucinostatin (mixture of A&B)
	Leucinostatin (mixture of A&B) 是来自Paecilomyces lilacinus 的九肽类复合物，具有抗生素活性。
T78486	cis-Nerolidol
	cis-Nerolidol，一种倍半萜醇，广泛存在于众多植物中，具抗氧化与抗菌活性，并能增强抗生素效果。
T81099	Staphyloferrin A
	Staphyloferrin A，一种铁载体蛋白，与抗生素结合对抗抗药性细菌性皮肤病进行研究。
T36990	Moenomycin Complex
	Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. [1] The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.[1]
T37008	Reveromycin A
	Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in oste...
T35667	Napyradiomycin A1 Napyradiomycin A1
	Napyradiomycin A1is a fungal metabolite originally isolated fromC. rubraand has diverse biological activities.1,2It is active againstS. aureus,M. luteus,B. anthracis,C. bovis, andM. smegmatis(MICs = 1.56-12.5 μg/ml).1Napyradiomycin A1is an estrogen receptor antagonist (IC50= 4.2 μM in rat uterine homogenates).2It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Ant...
T35741	Gliovirin
	Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease...

天然产物

Cat.No: T41044

Target: Glucosidase

Cat.No: T8347

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

7-Aminocephalosporanic acid

Cat.No: T0989

Synonym: 7-氨基头孢烷酸,7-ACA

Target: Others, Antibacterial, Antibiotic

Cat.No: T21498

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

3-Hydroxy-6-methoxyflavone

Cat.No: TN2943

Target: Others

Chrysosplenol D

Cat.No: TN1493

Synonym: 猫眼草酚D

Target: IL Receptor, NF-κB, JNK

Doxycycline (hyclate)

Cat.No: T1687L

Synonym: Doxycycline hydrochloride hemiethanolate hemihydrate,盐酸强力霉素,WC2031,Doxycycline hyclate

Target: MMP, ribosome, Antibacterial, Antibiotic

2,3-Diaminopropionic acid

Cat.No: T7335

Synonym: L-2,3-二氨基丙酸,L-2,3-Diaminopropionic acid

Target: Endogenous Metabolite

Cat.No: T1687

Synonym: Vibramycin,多西环素,Doxiciclina,Doxytetracycline,Doxycyclinum,强力霉素

Target: MMP, ribosome, Antibacterial, Antibiotic, Parasite

Cat.No: T13229

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Cat.No: T0814L

Synonym: Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid

Target: Antibacterial, Antibiotic

Cat.No: T1130

Synonym: 短杆菌肽,Gramicidinum,Gramicidine,Gramicidina

Target: MRP, Antibacterial, Antibiotic

Cat.No: T6062

Synonym: BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin

Target: ATPase, Mitophagy, Antibiotic, Autophagy, HSV, CRISPR/Cas9

Sisomicin Sulfate

Cat.No: T1219

Synonym: 硫酸西索米星,Pathomycin,Extramycin,硫酸西索紫苏

Target: Antibacterial, Antibiotic

Cat.No: T8641

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T0983

Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Target: Antibiotic

Erythromycin estolate

Cat.No: T15245

Synonym: Phtalic anhydride,ilosone

Target: Antibacterial

Cat.No: T6740

Synonym: 巴佛洛霉素A1,巴佛洛霉素 A1

Target: Apoptosis, Proton pump, Antibacterial, Antibiotic, Autophagy

3,4-Diaminotoluene

Cat.No: T7988

Target: Others

Doxorubicin hydrochloride

Cat.No: T1020

Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,盐酸多柔比星,盐酸阿霉素,NSC 123127

Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy

L-Aspartic acid potasium salt

Cat.No: T65269

Synonym: Aspartic acid potasium salt,Potassium L-aspartate

Target: Others

Dihydrocarminomycin

Cat.No: T24000

Synonym: Dihydrokarminomycin,Carminomycinol,RP-32999

Isopimaric acid

Cat.No: TN4319

Target: Antifection

Oxychelerythrine

Cat.No: TN4725

Target: Antifection

Leucinostatin (mixture of A&B)

Cat.No: T73954

Cat.No: T78486

Staphyloferrin A

Cat.No: T81099

Moenomycin Complex

Cat.No: T36990

Cat.No: T37008

Napyradiomycin A1

Cat.No: T35667

Synonym: Napyradiomycin A1

Cat.No: T35750

Cat.No: T35741

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