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Targets Recommended: Prostaglandin Receptor Chloride channel

213

抑制剂 & 化合物

24

天然产物

1

化合物库

1

TargetMol 试剂盒

15

重组蛋白

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Cat. No. Product Name
L2195 抗前列腺癌化合物库

2070 compounds
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选

化合物库

抗前列腺癌化合物库
Cat.No: L2195
Compounds: 2070
Cat. No. Product Name Form Specificity Of Inhibition
CL0097 Prostaglandin Receptor antagonist/agonist kit

Prostaglandin Receptor antagonist/agonist kit

TargetMol 试剂盒

Prostaglandin Receptor antagonist/agonist kit
Cat.No: CL0097
Cat. No. Product Name Target Signaling Pathways
T6307 Lubiprostone

芦比前列酮,SPI-0211,RU-0211,鲁比前列酮

Chloride channel Membrane transporter/Ion channel
Lubiprostone (RU-0211) 是一种 ClC-2 氯化物通道的激活剂,用于治疗特发性慢性便秘。
T15718 Latanoprost acid

GPR Endocrinology/Hormones; GPCR/G Protein
Latanoprost acid 是前列腺素受体的选择性激动剂,通过抑制 c-fos/NFATc1 通路抑制 RANKL 诱导的破骨细胞生成和功能。 拉坦前列素酸可用于降低眼内压力的研究。
T2531L Eprosartan

KF-108566J free base,Teveten

RAAS Endocrinology/Hormones
Eprosartan (SKF-108566J free base) 是一种具有选择性和竞争性的非肽类血管紧张素II受体拮抗剂,对AT1受体亚型具有高亲和力,可用作降压剂。Eprosartan 对血管紧张素 II 受体有抑制作用,在大鼠和人类肾上腺皮质膜中的 IC50 值分别为 9.2 nM 和 3.9 nM。
T1673 Acamprosate calcium

calcium acetylhomotaurinate,N-Acetylhomotaurine Calcium,Alcomed,阿坎酸钙,Sobriol,Campral EC,Calcium N-acetylhomotaurinate

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Acamprosate calcium (Campral EC) 是 GABA 受体激动剂和谷氨酸能系统调节剂,用于治疗酒精依赖。
T5171 Treprostinil Sodium

曲前列尼尔钠,UT-15

VEGFR; c-RET; Prostaglandin Receptor Angiogenesis; Apoptosis; GPCR/G Protein; Immunology/Inflammation; Tyrosine Kinase/Adaptors
Treprostinil Sodium (UT-15) 是有效的 DP1、IP 和 EP2 激动剂,EC50分别为0.6、1.9 和 6.2 nM。
T27066 Prostaglandin G/H synthase 1 inhibitor

CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide

Others Others
Prostaglandin G/H synthase 1 inhibitor (CP 74006) 是一种选择性D5D 抑制剂,IC(50)值为20nM。
T5150 Treprostinil

LRX-15,曲前列环素,Orenitram,曲前列尼尔,Remodulin

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Treprostinil (Orenitram) 是有效的 DP1、IP 和 EP2 激动剂,EC50分别为0.6、1.9 和 6.2 nM。
T2528 Latanoprost

Xalatan,PHXA41,拉坦前列腺素,拉坦前列素

GPR; Prostaglandin Receptor; RAR/RXR  Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
Latanoprost (Xalatan) 是前列腺素 F2α 类似物,是一种前列腺素受体激动剂,能够降低眼内压。
T5847 Cloprostenol sodium salt

ICI 80996 sodium salt,DL-Cloprostenol sodium,氯前列烯醇钠,氯前列烯醇纳,Cloprostenol sodium

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Cloprostenol sodium salt (ICI 80996 sodium salt) 是一种合成的前列腺素类似物,是 PGF2α受体的激动剂,具有黄体溶解性。
T2531 Eprosartan Mesylate

SKF-108566J,甲磺酸依普罗沙坦

RAAS Endocrinology/Hormones
Eprosartan Mesylate (SKF-108566J) 是一种具有选择性、竞争性血管紧张素 II 受体拮抗剂,是具有口服活性的非肽。它结合血管紧张素 II 受体,在大鼠和人类肾上腺皮质膜中的IC50值分别为 9.2 nM 和 3.9 nM,可用作降压剂。
TP1970L Prosaptide TX14(A) acetate

Prosaptide TX14(A) acetate(196391-82-9 free base)

ERK; GPR Endocrinology/Hormones; GPCR/G Protein; MAPK
Prosaptide TX14(A) acetate 是一种有效的 GPR37L1 和 GPR37 激动剂。 它增加雪旺细胞中的 ERK1 和 ERK2 磷酸化。
T21224 (+)-Fluprostenol

Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
(+)-Fluprostenol (AL-5848) 是前列腺素 F2 α 的类似物,是一种前列腺素 F2α 受体 PTGFR 激动剂,可降低输卵管糖蛋白 1 (OVGP1) 的表达。
T6849 Uprosertib

GSK2141795,GSK795,优普色替

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Uprosertib (GSK2141795) 是一种有效的,选择性的 Akt 广谱抑制剂,对 Akt1/Akt2/Akt3 的 IC50值分别为 180/328/38 nM。
T5841 Travoprost

曲伏前列素,Flu-Ipr,Fluprostenol isopropyl ester,AL6221

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Travoprost (Fluprostenol isopropyl ester) 是一种异丙基酯前药,是一种高亲和力的,选择性的 FP 前列腺素全受体激动剂。它能够降低眼压,有潜力应用于青光眼和眼高压。
T4546 Dinoprost tromethamine salt

Dinoprost Tromethamine,Zinoprost,Prostin F2 alpha,PGF2α THAM,Dinolytic,地诺前列素氨丁三醇,Prostaglandin F2α THAM

Apoptosis; Endogenous Metabolite; Prostaglandin Receptor; Autophagy; PROTAC Linker Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; PROTAC
Dinoprost tromethamine salt (PGF2α THAM) 是一种口服有效的前列腺素 F 受体激动剂。它是在子宫内膜腔上皮和黄体中局部产生的溶酶激素,在分娩过程中起关键作用。
T2538 Bimatoprost

AGN 192024,比马前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Bimatoprost (AGN 192024) 是一种氯前列醇衍生的酰胺,用作治疗开角型青光眼和高眼压症的抗高血压药。
T63349 Treprostinil diethanolamine

UT-15C

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Treprostinil diethanolamine (UT-15C) 是EP2、DP1和IP 的有效激动剂,对EP2、DP1、IP、EP1、EP4、EP3 和 FPKi 的值分别为 3.6、4.4、32.1、212、826、2505 和 4680 nM。Treprostinil diethanolamine 能够促使 cAMP 的上调,进而维持血管系统内的稳态,并造成人肺动脉的血管扩张。
T22285 Carboprost

15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α,卡前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Carboprost (15(S)-15-Methyl Prostaglandin F2α) 是一种前列腺素 F2α 的代谢稳定的合成类似物。它能够刺激子宫收缩并引起流产,可用于子宫收缩乏力引起的产后出血,以及在妊娠中期终止妊娠。
T15719 Latanoprostene bunod

LBN,NCX116

Others Others
Latanoprostene bunod (LBN) 是一氧化氮 (NO) 供体前列腺素 F2a 类似物,有用于开角型青光眼或高眼压 (OHT) 患者降低眼压 (IOP) 的局部眼科的研究潜力。
T20710 Ornoprostil

OU-1308,OU 1308,OU1308,Ronoprost

Ornoprostil, a prostaglandin E1 analogue, acts as a mucosal protectant.
T26925 Butaprost

Butaprostum,TR-4979,(R)-Butaprost

Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2). It exhibits an EC50 of 33 nM and a Ki of 2.4 μM when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-β/Smad2 signaling pathway [1] [2] [3].
T37991 15-keto Prostaglandin F2α

15-keto Prostaglandin F2α,15-keto PGF2α

Endogenous Metabolite; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism
15-keto Prostaglandin F2α 是 Prostaglandin F2α 的代谢物,可降低兔眼压。
T41251 Taprostene

Taprostene (CG-4203) 是一种合成的、化学稳定的前列环素 (PGI2) 类似物。Taprostene 对猫急性心肌缺血再灌注后内皮和心肌有保护作用。Taprostene 增强细胞保护作用,同时减少不必要的血液动力学影响。
T37231 (+)-Cloprostenol methyl ester

(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprosteno...
T30452 Bimatoprost isopropyl ester

17-phenyl trinor PGF2α-iPr,17-phenyl trinor PGF2α isopropyl ester

Bimatoprost isopropyl ester is an F-series prostaglandin analog, which has been approved as a hypotensive drug.
T10046 16,16-Dimethyl prostaglandin E2

16,16-dimethyl PGE2

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
T33710 Nocloprost

Nocloprost is a prostaglandin E2 analog with local gastroprotective and ulcer-healing activity.
T36045 1a,1b-dihomo Prostaglandin E2

1a,1b-dihomo Prostaglandin E2

1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid . This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.
T36165 8-iso-13,14-dihydro-15-keto Prostaglandin F2α

8-iso-13,14-dihydro-15-keto Prostaglandin F2α

8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into ra...
T36770 11-deoxy Prostaglandin E1

11-deoxy Prostaglandin E1

11-deoxy Prostaglandin E1 是前列腺素 E1类似物,具有支气管扩张活性,可抑制组胺诱导的支气管收缩,引起离体豚鼠的气管条松弛。
T36147 13,14-dihydro-15-keto Prostaglandin E1

13,14-dihydro-15-keto Prostaglandin E1

13,14-dihydro-15-keto Prostaglandin E1 可抑制 ADP 诱导的人离体富血小板血浆中的血小板聚集(IC50=14.8 μg/mL),也是 PGE1 代谢物。
T20855 Gemeprost

SC-37681,SC 37681,Carprost,Gemeprostum,Cervagem,Preglandin

Gemeprost, an analog of prostaglandin E1, is used for the treatment of obstetric bleeding. It is used to terminate pregnancy up to 24 weeks gestation together with mifepristone.
T31372 Delprostenate

A 2774,A2774,A-2774

Delprostenate is similar to PGF(2alpha), a naturally occurring prostaglandin used in medical labor induction and abortion drugs.
T32977 Luprostenol

Luprostenol is a bioactive chemical.
T73059 Acamprosate

Acamprosate 是一种口服活性原型神经调节剂。Acamprosate 可用于酒精依赖和酒精中毒的研究。
T29860 Alfaprostol

Alfaprostol is a bioactive chemical.
T36829 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimes...
T25362 Ecraprost

AS013,Circulase,AS 013,AS-013,Lipo-pro-prostaglandin E1

Ecraprost is used as a prodrug of prostaglandin E1.
T37919 Prostaglandin F1α

PGF1α,Prostaglandin F1α

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. [1] PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. [2] It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro. [3]
T37946 17-trifluoromethylphenyl trinor Prostaglandin F2α

17-trifluoromethylphenyl trinor Prostaglandin F2α

A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trin...
T29246 Cloprostenol isopropyl ester

(+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester,(+)-Cloprostenol isopropyl ester

Cloprostenol isopropyl ester is a PGF2α agonist and a similar synthetic prostaglandin F2α (PGF2α), which can induce luteal dissolution in mares during the luteal phase without causing clinical side effects or stress responses.
T12047 Misoprostol acid

Others Others
Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.
T36771 11-deoxy Prostaglandin F1α

11-deoxy Prostaglandin F1α

11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs.
T35944 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacologi...
TP1970 Prosaptide TX14(A)

Potent GPR37L1 and GPR37 agonist (EC50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs
T80552 Prostate Specific Antigen Substrate

Prostate Specific Antigen Substrate为前列腺特异性抗原(PSA)的荧光底物,专用于检测PSA的酶活性。
T36728 9-deoxy-9-methylene Prostaglandin E2

9-deoxy-9-methylene Prostaglandin E2

9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2 . 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2.
T24728 Rosaprostol

C 83

Rosaprostol is an agent of the anti-ulcer drug.
T124745 Verproside

Verproside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124745,CAS号为 50932-20-2。
T36546 Prostaglandin I3 (sodium salt)

Prostaglandin I3 (sodium salt)

PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.

化合物

Lubiprostone
Cat.No: T6307
Synonym: 芦比前列酮,SPI-0211,RU-0211,鲁比前列酮
Target: Chloride channel
Latanoprost acid
Cat.No: T15718
Synonym:
Target: GPR
Eprosartan
Cat.No: T2531L
Synonym: KF-108566J free base,Teveten
Target: RAAS
Acamprosate calcium
Cat.No: T1673
Synonym: calcium acetylhomotaurinate,N-Acetylhomotaurine Calcium,Alcomed,阿坎酸钙,Sobriol,Campral EC,Calcium N-acetylhomotaurinate
Target: GABA Receptor
Treprostinil Sodium
Cat.No: T5171
Synonym: 曲前列尼尔钠,UT-15
Target: VEGFR, c-RET, Prostaglandin Receptor
Prostaglandin G/H synthase 1 inhibitor
Cat.No: T27066
Synonym: CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide
Target: Others
Treprostinil
Cat.No: T5150
Synonym: LRX-15,曲前列环素,Orenitram,曲前列尼尔,Remodulin
Target: Prostaglandin Receptor
Latanoprost
Cat.No: T2528
Synonym: Xalatan,PHXA41,拉坦前列腺素,拉坦前列素
Target: GPR, Prostaglandin Receptor, RAR/RXR 
Cloprostenol sodium salt
Cat.No: T5847
Synonym: ICI 80996 sodium salt,DL-Cloprostenol sodium,氯前列烯醇钠,氯前列烯醇纳,Cloprostenol sodium
Target: Prostaglandin Receptor
Eprosartan Mesylate
Cat.No: T2531
Synonym: SKF-108566J,甲磺酸依普罗沙坦
Target: RAAS
Prosaptide TX14(A) acetate
Cat.No: TP1970L
Synonym: Prosaptide TX14(A) acetate(196391-82-9 free base)
Target: ERK, GPR
(+)-Fluprostenol
Cat.No: T21224
Synonym: Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸
Target: Prostaglandin Receptor
Uprosertib
Cat.No: T6849
Synonym: GSK2141795,GSK795,优普色替
Target: Akt
Travoprost
Cat.No: T5841
Synonym: 曲伏前列素,Flu-Ipr,Fluprostenol isopropyl ester,AL6221
Target: Prostaglandin Receptor
Dinoprost tromethamine salt
Cat.No: T4546
Synonym: Dinoprost Tromethamine,Zinoprost,Prostin F2 alpha,PGF2α THAM,Dinolytic,地诺前列素氨丁三醇,Prostaglandin F2α THAM
Target: Apoptosis, Endogenous Metabolite, Prostaglandin Receptor, Autophagy, PROTAC Linker
Bimatoprost
Cat.No: T2538
Synonym: AGN 192024,比马前列素
Target: Prostaglandin Receptor
Treprostinil diethanolamine
Cat.No: T63349
Synonym: UT-15C
Target: Prostaglandin Receptor
Carboprost
Cat.No: T22285
Synonym: 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α,卡前列素
Target: Prostaglandin Receptor
Latanoprostene bunod
Cat.No: T15719
Synonym: LBN,NCX116
Target: Others
Ornoprostil
Cat.No: T20710
Synonym: OU-1308,OU 1308,OU1308,Ronoprost
Target:
Butaprost
Cat.No: T26925
Synonym: Butaprostum,TR-4979,(R)-Butaprost
Target:
15-keto Prostaglandin F2α
Cat.No: T37991
Synonym: 15-keto Prostaglandin F2α,15-keto PGF2α
Target: Endogenous Metabolite, Prostaglandin Receptor
Taprostene
Cat.No: T41251
Synonym:
Target:
(+)-Cloprostenol methyl ester
Cat.No: T37231
Synonym:
Target:
Bimatoprost isopropyl ester
Cat.No: T30452
Synonym: 17-phenyl trinor PGF2α-iPr,17-phenyl trinor PGF2α isopropyl ester
Target:
16,16-Dimethyl prostaglandin E2
Cat.No: T10046
Synonym: 16,16-dimethyl PGE2
Target: Prostaglandin Receptor
Nocloprost
Cat.No: T33710
Synonym:
Target:
1a,1b-dihomo Prostaglandin E2
Cat.No: T36045
Synonym: 1a,1b-dihomo Prostaglandin E2
Target:
8-iso-13,14-dihydro-15-keto Prostaglandin F2α
Cat.No: T36165
Synonym: 8-iso-13,14-dihydro-15-keto Prostaglandin F2α
Target:
11-deoxy Prostaglandin E1
Cat.No: T36770
Synonym: 11-deoxy Prostaglandin E1
Target:
13,14-dihydro-15-keto Prostaglandin E1
Cat.No: T36147
Synonym: 13,14-dihydro-15-keto Prostaglandin E1
Target:
Gemeprost
Cat.No: T20855
Synonym: SC-37681,SC 37681,Carprost,Gemeprostum,Cervagem,Preglandin
Target:
Delprostenate
Cat.No: T31372
Synonym: A 2774,A2774,A-2774
Target:
Luprostenol
Cat.No: T32977
Synonym:
Target:
Acamprosate
Cat.No: T73059
Synonym:
Target:
Alfaprostol
Cat.No: T29860
Synonym:
Target:
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
Cat.No: T36829
Synonym: 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
Target:
Ecraprost
Cat.No: T25362
Synonym: AS013,Circulase,AS 013,AS-013,Lipo-pro-prostaglandin E1
Target:
Prostaglandin F1α
Cat.No: T37919
Synonym: PGF1α,Prostaglandin F1α
Target:
17-trifluoromethylphenyl trinor Prostaglandin F2α
Cat.No: T37946
Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α
Target:
Cloprostenol isopropyl ester
Cat.No: T29246
Synonym: (+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester,(+)-Cloprostenol isopropyl ester
Target:
Misoprostol acid
Cat.No: T12047
Synonym:
Target: Others
11-deoxy Prostaglandin F1α
Cat.No: T36771
Synonym: 11-deoxy Prostaglandin F1α
Target:
15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
Cat.No: T35944
Synonym: 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
Target:
Prosaptide TX14(A)
Cat.No: TP1970
Synonym:
Target:
Prostate Specific Antigen Substrate
Cat.No: T80552
Synonym:
Target:
9-deoxy-9-methylene Prostaglandin E2
Cat.No: T36728
Synonym: 9-deoxy-9-methylene Prostaglandin E2
Target:
Rosaprostol
Cat.No: T24728
Synonym: C 83
Target:
Verproside
Cat.No: T124745
Synonym:
Target:
Prostaglandin I3 (sodium salt)
Cat.No: T36546
Synonym: Prostaglandin I3 (sodium salt)
Target:
Cat. No. Product Name Target Signaling Pathways
T14865 Carboprost tromethamine

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Carboprost tromethamine 是合成的前列腺素 F2α的15-甲基类似物,能有效促进子宫的规律收缩,显着减少产中及产后出血量。
TQ0203 Tafluprost

MK2452,AFP-168,他氟前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Tafluprost 是一种抗青光眼前列腺素(PG)类似物。
TN7109 Prosaikogenin G

RAAS Endocrinology/Hormones
Prosaikogenin G 是一种从柴胡的根中分离出的化合物,是 Saikosaponin d 在胃肠道中的衍生物。Prosaikogenin G 对 Angiotensin II 诱导的大鼠系膜细胞增殖具有明显的抑制作用,同时对肾脏有保护作用。
T20939 Bimatoprost acid

17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α

GPR Endocrinology/Hormones; GPCR/G Protein
Bimatoprost acid (17-phenyl trinor PGF2α) 是一种代谢稳定的 PGF2α 类似物,对 FP 受体具有潜在的拮抗活性。与 PGF2α 相比,它与绵羊黄体细胞上的 FP 受体结合的相对效力为 756%。
TN6864 Prosaikogenin F

前柴胡皂苷F

Others Others
Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) 是一种单糖苷,具有溶血和抗癌特性。
TN2335 Prosaikogenin D

Prosapogenin D,柴胡次皂苷D

Others Others
Prosaikogenin D (Prosapogenin D) 是一种天然产物,从柴胡 Buleurum bicaule Helm 的根中提取,具有抗癌活性。
T1626 Prostaglandin E1

前列地尔,PGE1,列腺素E1,Alprostadil

Endogenous Metabolite; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism
Prostaglandin E1 (Alprostadil) 是一种前列腺素受体配体,对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集,可作为血管扩张剂用于外周血管疾病的研究。
T0883 Tramiprosate

Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸

Beta Amyloid; GABA Receptor Membrane transporter/Ion channel; Neuroscience
Tramiprosate (Alzhemed) 是一种具有口服活性的、可透过血脑屏障的天然氨基酸,存在于各种红色海藻中,能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的活性。
T5014 Prostaglandin E2

地诺前列酮,前列腺素 E2,PGE2,Dinoprostone,Prostaglandin E2 (PGE2)

Endogenous Metabolite; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism
Prostaglandin E2 (PGE2) 是一种天然激素,参与人体内的各种生理过程,包括平滑肌收缩和放松、调节血管扩张和收缩、调节血压和炎症调节。
T15133 Dinoprost

Prostaglandin F2a,PGF2α,地诺前列素

Endogenous Metabolite Metabolism
Dinoprost (Prostaglandin F2a) 是口服有效的、内源性的前列腺素 F 受体激动剂。它是在子宫内膜腔上皮和黄体中局部产生的溶酶激素。它在分娩过程中起关键作用。
T5S1252 Prosapogenin A

重楼皂苷E,Progenin III

Apoptosis; Others Apoptosis; Others
Prosapogenin A (Progenin III) 是藜芦中的一种天然产物,通过抑制 STAT3 信号通路和糖酵解,可诱导人癌细胞凋亡,有抗癌作用。
TN2105 Proscillaridin A

Topoisomerase DNA Damage/DNA Repair
Proscillaridin A 是从Drimia robusta 中提取的一种天然产物。是强力的拓扑异构酶 I 和 II 的抑制剂,IC50值分别为 30 nM 和 100 nM。
TN4833 Prostephanaberrine

Others Others
Prostephanaberrine is a natural product from Stephania japonica.
TN2104 Prosapogenin CP6

次皂甙元CP6

Others Others
Prosapogenin CP6 is a natural product
T22473 15-deoxy-Δ-12,14-Prostaglandin J2

Others Others
15-deoxy-Δ-12,14-Prostaglandin J2 is a PPARγ agonist.
T21441 Prostratin

12-Deoxyphorbol-13-acetate

Prostratin, a protein kinase C activator, has been shown to exhibit promising therapeutic potential against other diseases such as cancer and Alzheimer's disease. Prostratin has the potential to be useful in the treatment of HIV as it could flush viral re
T41137 Prosaikogenin A

Prosaikogenin A, a triterpene saponin extracted from Clinopodium chinense, exhibits notable platelet aggregation promotion activity, indicated by an EC 50 value of 12.2 μM.
T41138 Prosaikogenin H

Prosaikogenin H, an intestinal metabolite derived from saikosaponin, exhibits weak hemolytic activity.
T13831 Prostaglandin D2

PGD2

Endogenous Metabolite Metabolism
Prostaglandin D2 (PGD2) (PGD2) 是哺乳动物大脑中主要产生的前列腺素之一,为最有效的内源性睡眠促进剂之一,并通过抑制炎症发挥保护作用。
T37164 8-Isoprostaglandin F2α

8-iso Prostaglandin F2α

8-Isoprostaglandin F2α 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T37164,CAS号为 27415-26-5。
TN6085 6-Methoxyspirotryprostatin B

Spirotryprostatin G

6-Methoxyspirotryprostatin B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6085,CAS号为 1031727-28-2。
TN6083 Spirotryprostatin A

Spirotryprostatin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6083,CAS号为 182234-25-9。
T82460 Epicoprostanol

Epicoprostanol是一种存在于脂肪粒中的化学化合物。
TN5190 Tryprostatin A

Topoisomerase; Antifection DNA Damage/DNA Repair; Microbiology/Virology
Tryprostatin A is an inhibitor of breast cancer resistance protein. Tryprostatin A and tryprostatin B are indole alkaloid-based fungal products that inhibit mammalian cell cycle at the G2/M phase.

天然产物

Carboprost tromethamine
Cat.No: T14865
Synonym:
Target: Prostaglandin Receptor
Tafluprost
Cat.No: TQ0203
Synonym: MK2452,AFP-168,他氟前列素
Target: Prostaglandin Receptor
Prosaikogenin G
Cat.No: TN7109
Synonym:
Target: RAAS
Bimatoprost acid
Cat.No: T20939
Synonym: 17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α
Target: GPR
Prosaikogenin F
Cat.No: TN6864
Synonym: 前柴胡皂苷F
Target: Others
Prosaikogenin D
Cat.No: TN2335
Synonym: Prosapogenin D,柴胡次皂苷D
Target: Others
Prostaglandin E1
Cat.No: T1626
Synonym: 前列地尔,PGE1,列腺素E1,Alprostadil
Target: Endogenous Metabolite, Prostaglandin Receptor
Tramiprosate
Cat.No: T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸
Target: Beta Amyloid, GABA Receptor
Prostaglandin E2
Cat.No: T5014
Synonym: 地诺前列酮,前列腺素 E2,PGE2,Dinoprostone,Prostaglandin E2 (PGE2)
Target: Endogenous Metabolite, Prostaglandin Receptor
Dinoprost
Cat.No: T15133
Synonym: Prostaglandin F2a,PGF2α,地诺前列素
Target: Endogenous Metabolite
Prosapogenin A
Cat.No: T5S1252
Synonym: 重楼皂苷E,Progenin III
Target: Apoptosis, Others
Proscillaridin A
Cat.No: TN2105
Synonym:
Target: Topoisomerase
Prostephanaberrine
Cat.No: TN4833
Synonym:
Target: Others
Prosapogenin CP6
Cat.No: TN2104
Synonym: 次皂甙元CP6
Target: Others
15-deoxy-Δ-12,14-Prostaglandin J2
Cat.No: T22473
Synonym:
Target: Others
Prostratin
Cat.No: T21441
Synonym: 12-Deoxyphorbol-13-acetate
Target:
Prosaikogenin A
Cat.No: T41137
Synonym:
Target:
Prosaikogenin H
Cat.No: T41138
Synonym:
Target:
Prostaglandin D2
Cat.No: T13831
Synonym: PGD2
Target: Endogenous Metabolite
8-Isoprostaglandin F2α
Cat.No: T37164
Synonym: 8-iso Prostaglandin F2α
Target:
6-Methoxyspirotryprostatin B
Cat.No: TN6085
Synonym: Spirotryprostatin G
Target:
Spirotryprostatin A
Cat.No: TN6083
Synonym:
Target:
Epicoprostanol
Cat.No: T82460
Synonym:
Target:
Tryprostatin A
Cat.No: TN5190
Synonym:
Target: Topoisomerase, Antifection
Cat. No. Product Name Species Expression System
TMPY-03848 Protein S/PROS1 Protein, Human, Recombinant (His)

PS21,PSA,PS23,PS22,THPH6,PS25,Protein S,THPH5,protein S (α),...

Human HEK293 Cells
Protein S/PROS1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 74.1 kDa and the accession number is P07225.
TMPY-06708 Protein S/PROS1 Protein, Mouse, Recombinant (His)

protein S (α),AW214361,protein S (alpha)

Mouse HEK293 Cells
Protein S/PROS1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.75 kDa and the accession number is Q08761.
TMPY-06315 Protein S/PROS1 Protein, Cynomolgus, Recombinant (His)

protein S (alpha),protein S (α)

Cynomolgus HEK293 Cells
Protein S/PROS1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 74.18 kDa and the accession number is A0A7N9CCZ7.
TMPY-03120 Prostaglandin D2 Synthase Protein, Human, Recombinant (His)

PDS,L-PGDS,PGDS,PGDS2,LPGDS,PGD2,prostaglandin D2 s...

Human HEK293 Cells
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222.
TMPY-04510 PSAP/Prosaposin Protein, Human, Recombinant (His)

prosaposin,SAP1,GLBA

Human HEK293 Cells
Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previously localized to 10q21-->q22 by isotopic in situ hybridization using a human prosaposin cDNA as a probe. Using fluorescence in situ hybridization with a mouse genomic prosaposin fragment as probe, confirms the localization of PSAP and precisely maps it to band 10q22.1. PSAP/Pro...
TMPY-02672 Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)

5'-NT,9.104100899-104272570.1,Ppal,A030005E02Rik,PAP,Lap,aci...

Mouse HEK293 Cells
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
TMPY-04624 Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)

Ptgs3,L-PGDS,prostaglandin D2 synthase 21kDa (brain...

Mouse HEK293 Cells
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1.
TMPJ-01439 Asprosin Protein, Mouse, Recombinant (His)

Fbn-1,Fbn1,Fibrillin-1,Asprosin

Mouse HEK293 Cells
Asprosin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-8xHis tag. The predicted molecular weight is 30 KDa and the accession number is AAA56840.1.
TMPJ-01451 Asprosin Protein, Human, Recombinant (His)

Asprosin,FBN,Fibrillin-1,FBN1

Human HEK293 Cells
Asprosin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-8xHis tag. The predicted molecular weight is 25-35 KDa and the accession number is P35555.
TMPY-00905 Prostasin/PRSS8 Protein, Human, Recombinant (His)

CAP1,protease, serine, 8,PROSTASIN

Human HEK293 Cells
Prostasin/PRSS8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q16651-1.
TMPY-02783 Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His)

C79772,CAP1,protease, serine, 8,fr,AI313909,2410039E18Rik,mC...

Mouse Baculovirus Insect Cells
Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.3 kDa and the accession number is EDL17608.1.
TMPY-00209 PSAP/Prosaposin Protein, Rat, Recombinant (His)

prosaposin

Rat HEK293 Cells
Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previously localized to 10q21-->q22 by isotopic in situ hybridization using a human prosaposin cDNA as a probe. Using fluorescence in situ hybridization with a mouse genomic prosaposin fragment as probe, confirms the localization of PSAP and precisely maps it to band 10q22.1. PSAP/Pro...
TMPY-02155 Prostatic Acid Phosphatase Protein, Human, Recombinant (His)

5'-NT,acid phosphatase, prostate,PAP,ACP-3,ACP3

Human HEK293 Cells
Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2.
TMPY-05069 Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)

prostaglandin D2 synthase 21kDa (brain)

Rat HEK293 Cells
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A6JT70.
TMPY-04997 Prostasin/PRSS8 Protein, Rat, Recombinant (His)

protease, serine, 8

Rat HEK293 Cells
Prostasin/PRSS8 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.9 kDa and the accession number is Q9ES87.

重组蛋白

Protein S/PROS1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03848
Species: Human
Expression System: HEK293 Cells
Protein S/PROS1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06708
Species: Mouse
Expression System: HEK293 Cells
Protein S/PROS1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06315
Species: Cynomolgus
Expression System: HEK293 Cells
Prostaglandin D2 Synthase Protein, Human, Recombinant (His)
Cat.No: TMPY-03120
Species: Human
Expression System: HEK293 Cells
PSAP/Prosaposin Protein, Human, Recombinant (His)
Cat.No: TMPY-04510
Species: Human
Expression System: HEK293 Cells
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02672
Species: Mouse
Expression System: HEK293 Cells
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04624
Species: Mouse
Expression System: HEK293 Cells
Asprosin Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01439
Species: Mouse
Expression System: HEK293 Cells
Asprosin Protein, Human, Recombinant (His)
Cat.No: TMPJ-01451
Species: Human
Expression System: HEK293 Cells
Prostasin/PRSS8 Protein, Human, Recombinant (His)
Cat.No: TMPY-00905
Species: Human
Expression System: HEK293 Cells
Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His)
Cat.No: TMPY-02783
Species: Mouse
Expression System: Baculovirus Insect Cells
PSAP/Prosaposin Protein, Rat, Recombinant (His)
Cat.No: TMPY-00209
Species: Rat
Expression System: HEK293 Cells
Prostatic Acid Phosphatase Protein, Human, Recombinant (His)
Cat.No: TMPY-02155
Species: Human
Expression System: HEK293 Cells
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)
Cat.No: TMPY-05069
Species: Rat
Expression System: HEK293 Cells
Prostasin/PRSS8 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04997
Species: Rat
Expression System: HEK293 Cells
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