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Search Results for " pk1 "

Targets Recommended: Dopamine Receptor

65

抑制剂 & 化合物

18

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6835	Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。
T39195	YM-244769 dihydrochloride	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	YM-244769 dihydrochloride 是一种有效的 Na+/Ca2+ exchange 3 (NCX3) 抑制剂，IC50 为 18 nM。 YM-244769 dihydrochloride 对神经元和肾脏具有有效的保护作用。
T9888	YM-244769 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) 是一种有效的 Na+/Ca2+ exchange 3 (NCX3) 抑制剂，IC50 为 18 nM。 YM-244769 对神经元和肾脏具有有效的保护作用。
T4459	PK11000	DNA Alkylator/Crosslinker	DNA Damage/DNA Repair
	PK11000 是一种烷化剂，可通过共价半胱氨酸修饰来稳定野生型和突变型p53的 DNA 结合结构域。
T7703	PK11007	Reactive Oxygen Species; p53	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	PK11007 是一种温和的硫醇烷基化剂，具有抗癌活性。它通过两个表面暴露的半胱氨酸的选择性烷基化来稳定 p53。它通过增加活性氧水平诱导突变的 p53癌细胞死亡。
T63055	RIPK1-IN-9	RIP kinase	Apoptosis; NF-κB
	RIPK1-IN-9是是一种强效且具有选择性的 RIPK1抑制剂，是一种二氢萘酮化合物。RIPK1-IN-9对 U937细胞和 L929细胞具有抑制作用，IC50分别为2 nM 和1.3 nM。
T72081	CpCDPK1/TgCDPK1-IN-2	Parasite	Microbiology/Virology
	CpCDPK1/TgCDPK1-IN-2 是 CpCDPK1 和 TgCDPK1 双重抑制剂，对 CpCDPK1 和 TgCDPK1 有抑制这样，IC50 值分别为 12 和 5 nM。CpCDPK1/TgCDPK1-IN-2 可用于研究弓形虫 (T. gondii)、细小隐孢子虫 (C. parvum) 和隐孢子虫 (C. hominus) 等顶复门原生动物感染相关疾病。
T72033	pCDPK1/TgCDPK1-IN-3	Parasite	Microbiology/Virology
	CpCDPK1/TgCDPK1-IN-3 是一种 CpCDPK1 和 TgCDPK1双重抑制剂，对 CpCDPK1 的IC50 为 0.003µM ，对TgCDPK1 的IC50 为 0.0036 µM。CpCDPK1/TgCDPK1-IN-3 可用于研究像弓形虫、细小隐孢子虫和隐孢子虫等顶复门原生动物相关疾病感染。
T12731	RIPK1-IN-7	RIP kinase	Apoptosis; NF-κB
	RIPK1-IN-7 是一种选择性有效的 RIPK1 抑制剂，Kd 值为 4 nM，IC50值为 11 nM。在实验性 B16 黑色素瘤肺转移模型中表现出优异的抗转移活性。
T78605	CpCDPK1/TgCDPK1-IN-1	Bcr-Abl; Src	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	CpCDPK1/TgCDPK1-IN-1 是一种高效的 CpCDPK1 和 TgCDPK1 双重抑制剂，抑制 Abl 和 Src，具有抗寄生虫活性，适用于研究弓形虫感染和隐孢子虫病。
T78268	Anti-Mouse NK1.1 Antibody (PK136)
	Anti-Mouse NK1.1 Antibody (PK136) 是鼠源靶向 NK1.1的IgG2a类抗体，可消除外周血、脾脏和肺组织中的NK1.1和NK1.1NKT细胞，抑制 NK1.1 信号传导，可用于研究心肺衰竭。
T9017	HPK1-IN-2 Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2	Others; FLT; Src	Angiogenesis; Others; Tyrosine Kinase/Adaptors
	HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) 是一种有效且具有口服活性的造血祖细胞激酶-1 抑制剂(HPK1；IC50<0.05 µM)。它还抑制 Lck (0.05 µM<IC50<0.5 µM) 和 Flt3 (IC50<0.05 µM) 激酶活性，具有抗肿瘤活性。
T7897	PK150	Others; Antibacterial	Microbiology/Virology; Others
	PK150 是一种 Sorafenib 类似物，具有抗菌活性。它抑制甲氧西林敏感金黄色葡萄球菌，耐甲氧西林金黄色葡萄球菌，万古霉素中介金黄色葡萄球菌的 MIC 分别为 0.3，0.3-1，0.3 µM。
T12730	RIPK1-IN-4	RIP kinase	Apoptosis; NF-κB
	RIPK1-IN-4 是有效的 II 型激酶受体相互作用蛋白1 (RIP1) 激酶抑制剂，并且与 DL1-out 无活性形式的 RIP1 结合。RIPK1-IN-4抑制 RIP1 和 ADP-Glo 激酶，IC50 分别是 16 nM 和 10 nM。
T9470	HPK1-IN-7	MAPK	MAPK
	HPK1-IN-7 是一种口服有活性的、有效的HPK1(造血祖细胞激酶1, MAP4K1) 抑制剂，其IC50值为2.6 nM，具有强大的家族及激酶组选择性。它对 IRAK4 (59 nM) 和 GLK (140 nM) 具有选择性。当它与抗 PD1联合使用时，对 MC38 同基因肿瘤模型表现出极大的疗效。
T11943	MAPK13-IN-1	p38 MAPK	MAPK
	MAPK13-IN-1 是一种有效的 MAPK13 (p38δ) 抑制剂（IC50：620 nM）。
T40350	HPK1-IN-4 HPK1-IN-4	MAPK	MAPK
	HPK1-IN-4是一种HPK1（MAPK41）抑制剂，IC 50为0.061 nM。HPK1-IN-4常被作为临床前免疫治疗工具化合物。
T79790	ALPK1-IN-3	NF-κB	NF-κB
	ALPK1-IN-3 (T007)为ALPK1抑制剂。在脓毒症引起的急性肾损伤动物模型中，ALPK1-IN-3能够降低肾脏促炎基因的表达并增加动物的存活率。
T60862	RIPK1-IN-15
	RIPK1-IN-15 (Compound 2.5) 是 RIPK1 的有效抑制剂，在神经退行性疾病、自身免疫性疾病和炎症性疾病研究中具有潜力。
T39709	HPK1-IN-19 HPK1-IN-19
	HPK1-IN-19 is an inhibitor of hematopoietic progenitor kinase 1 (HPK1).
T62628	HPK1-IN-12
	HPK1-IN-12 是一种 HPK1 的有效抑制剂。HPK1 为造血祖细胞中克隆出来的丝氨酸/苏氨酸蛋白激酶，属于哺乳动物Ste-20相关蛋白激酶MAP4K 家族。HPK1-IN-12 具有潜力进行 HPK1 相关疾病的研究。
T72052	HPK1-IN-34
	HPK1-IN-34是一种造血祖细胞激酶1(HPK1)抑制剂，IC50<100nM。
T12729	RIPK1-IN-3	Others	Others
	RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.
T62742	HPK1-IN-11
	HPK1-IN-11 是一种有效的 HPK1 抑制剂。其中 HPK1 是一种从造血祖细胞中克隆出来的丝氨酸/苏氨酸蛋白激酶，属于哺乳动物 Ste-20 相关蛋白激酶 MAP4K 家族成员。HPK1-IN-11 具有潜力进行 HPK1 相关疾病的研究。
T78688	HPK1-IN-35
	HPK1-IN-35，作为一种选择性的HPK1抑制剂，表现出了3.5 nM的强效IC50。该化合物能够抑制p-SLP76的表达并增强IL-2的分泌。
T16547	PK14105	Others	Others
	PK14105 has been evaluated biologically as a potential radioligand for positron emission tomography (PET) studies targeting peripheral benzodiazepine binding sites (PBBS) receptors. When administered to rats with unilaterally lesioned striata, PK14105 was observed to quickly cross the blood-brain barrier, displaying significant radioactivity retention in the lesioned striatum, in contrast to the unlesioned striatum or cerebellar vermis. Additionally, PK14105 has the capability to inhibit recepto...
T62723	RIPK1-IN-12
	RIPK1-IN-12 是一种 RIPK1 的有效抑制剂。RIPK1-IN-12 对人和小鼠细胞的坏死性凋亡表现出抑制作用，EC50 值分别为 1.6 和 2.9 nM.
T78852	HPK1-IN-39
	HPK1-IN-39（Compound 10n）为一选择性HPK1抑制剂，IC50值为29 nM。该化合物能抑制SLP76磷酸化，可用于癌症免疫治疗研究。
T79787	HPK1-IN-37
	HPK1-IN-37（又名compound A85）是一种选择性抑制剂，它通过竞争性地结合到激酶的ATP结合位点来抑制HPK1活性。该化合物在体外研究中表现出对HPK1的高度选择性，并且展示了优异的药理学特性。HPK1-IN-37在多种生物学测定中显示了潜在的疗效以及较好的生物可利用性，使其成为HPK1相关疾病研究的重要工具。
T61887	RIPK1-IN-13
	RIPK1-IN-13 (Compound 8) 是一种有效的RIPK1抑制剂（IC50= 1139 nM）。通过抑制 RIPK1，RIPK1-IN-13 能够阻断坏死性凋亡途径的激活。RIPK1-IN-13 在炎症性疾病中具有研究潜力。
T72036	HPK1-IN-36	Others	Others
	HPK1-IN-36（compound 2）作为一种HPK1抑制剂，表现出高效性，其IC50为0.5 nM。
T63176	ALPK1-IN-1
	ALPK1-IN-1 (Compound A001) 是一种 α-激酶 1 (ALPK1) 的有效抑制剂。其中 ALPK1 是一种胞质内丝/苏氨酸蛋白激酶，利用与叉头相关结构域 (TIFA) 依赖的促炎 NF-κB 信号通路的 TRAF 蛋白相互作用，在激活对细菌的先天免疫反应中发挥重要作用。
T79788	HPK1-IN-38
	HPK1-IN-38（化合物15）为MAP4K1/HPK1抑制剂，适用于HPK1相关疾病研究。
T60973	HPK1-IN-24
	HPK1-IN-24 (example 51) 可用于癌症领域研究，它是造血祖细胞激酶 1 (HPK1)的抑制剂 (Ki = 100 nM)。
T73186	HPK1-IN-31
	HPK1-IN-31 是一种具有口服活性的造血祖细胞激酶 1 (HPK1) 抑制剂，IC50值为 0.8 nM。HPK1-IN-31 具有抗肿瘤活性，在免疫治疗方面具有巨大的潜力。
T63541	HPK1-IN-27
	HPK1-IN-27 是 HPK1 的有效抑制剂。其中 MAP4K1 也叫造血祖细胞激酶 1 (HPK1)，是一种生发中心激酶家族的成员，是一种丝氨酸/苏氨酸激酶。HPK1-IN-27 对癌症疾病表现出研究潜力。
T63469	RIPK1-IN-8
	RIPK1-IN-8 是一种氨基咪唑并吡啶，是选择性的 RIPK1 有效抑制剂 (IC50: 4 nM)。RIPK1-IN-8 对炎症性疾病具有研究潜力。
T63270	HPK1-IN-29
	HPK1-IN-29 是 HPK1 有效的抑制剂，其中造血祖细胞激酶 1 (HPK1) 是一种树突状细胞 (DC)、T 细胞和 B 细胞活化反应的负调节剂。HPK1-IN-29 能够提高人体的抗肿瘤免疫力，表现出研究免疫相关疾病，尤其是肿瘤的潜力。
T29258	(R)-N-Desmethyl PK11195 (R)-N-Desmethyl PK 11195,(R)-N-Desmethyl PK-11195,(R)-N Desmethyl PK11195,(R) N-Desmethyl PK11195
	(R)-N-Desmethyl PK11195 is a precursor for (R)-[N-Methyl-11C-]PK11195.
T61449	HPK1-IN-18
	HPK1-IN-18 is a highly effective and specific HPK1 inhibitor. HPK1, a MAP kinase kinase kinase kinases (MAP4K) member, was initially isolated from hematopoietic progenitor cells. This compound, known as HPK1-IN-18, is valuable for investigating, preventing, or managing diseases or conditions linked to HPK1 activity, such as cancer[1].
T81268	RIPK1-IN-17	RIP kinase	Apoptosis; NF-κB
	RIPK1/3-IN-1（Compound 10）是RIPK1与RIPK3的抑制剂，其通过抑制RIPK1、RIPK3及MLKL的磷酸化作用，特异性地抑制坏死性凋亡。
T73149	HPK1-IN-33
	HPK1-IN-33（化合物21）是造血祖细胞激酶1（HPK1）的高效抑制剂，其Ki值为1.7 µM。此化合物在Jurkat WT细胞中抑制IL-2产生的EC50为286 nM，而在Jurkat HPK1 KO细胞中的EC50则大于10000 nM。
T62800	HPK1-IN-16
	HPK1-IN-16 是一种选择性的、有效的 HPK1 抑制剂。其中造血祖细胞激酶 1（HPKl）从造血祖细胞中克隆出来，是 MAP 激酶激酶（MAP4Ks）家族的成员之一。HPK1-IN-16 能够用于与 HPK1 活性相关的疾病或病症（如癌症）的研究、预防或改善。
T63659	HPK1-IN-10
	HPK1-IN-10 是 HPK1 的有效抑制剂。HPK1 是一种丝氨酸/苏氨酸蛋白激酶，由造血祖细胞克隆得到，是哺乳动物Ste-20相关蛋白激酶MAP4K 家族成员之一。HPK1-IN-10 对HPK1 相关疾病具有研究潜力。
T62632	HPK1-IN-21
	HPK1-IN-21 是一种有效的、口服具有活力的 HPK1 激酶抑制剂，其 Ki 值为 0.8 nM。。
T62927	HPK1-IN-22
	HPK1-IN-22 (compound ZYF0033) 是一种造血祖细胞激酶 1 (HPK1) 抑制剂，基于 MBP 蛋白的磷酸化抑制作用的 IC50小于 10 nM。HPK1-IN-22 能够减少 SLP76 (丝氨酸 376) 的磷酸化，促进抗癌免疫反应。HPK1-IN-22 可以抑制 4T-1 同基因小鼠模型中的肿瘤生长，增加 DC、NK 细胞和 CD107a+CD8+T 细胞的肿瘤内浸润，但会减少 T 细胞、PD-1+CD8+T 细胞、TIM-3+CD8+T 细胞和 LAG3+CD8+T 细胞的浸润。
T64064	RIPK1-IN-10
	RIPK1-IN-10 是 RIPK1 的有效抑制剂。
T62629	HPK1-IN-13
	HPK1-IN-13 是一种 HPK1 的有效抑制剂。HPK1 为造血祖细胞中克隆出来的丝氨酸/苏氨酸蛋白激酶，属于哺乳动物Ste-20相关蛋白激酶MAP4K 家族。HPK1-IN-13 具有潜力进行 HPK1 相关疾病的研究。
T62315	HPK1-IN-30
	HPK1-IN-30 是一种 HPK1 的有效抑制剂。其中 MAP4K1 也称为造血祖细胞激酶 1 (HPK1)，是一种丝氨酸/苏氨酸激酶，属于生发中心激酶家族。HPK1-IN-30 具有潜力进行癌症疾病的研究。
T63046	HPK1-IN-15
	HPK1-IN-15 是一种选择性的、有效的 HPK1 抑制剂。其中从造血祖细胞克隆的造血祖细胞激酶1 (HPK1) 属于 MAP4Ks 家族。HPK1-IN-15 能够用于与 HPK1 活性相关的疾病或病症 (如癌症) 的研究、预防或改善。

化合物

Fenoldopam mesylate

Cat.No: T6835

Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐

Target: Dopamine Receptor

YM-244769 dihydrochloride

Cat.No: T39195

Target: Calcium Channel

Cat.No: T9888

Synonym: 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-

Target: Calcium Channel

Cat.No: T4459

Target: DNA Alkylator/Crosslinker

Cat.No: T7703

Target: Reactive Oxygen Species, p53

Cat.No: T63055

Target: RIP kinase

CpCDPK1/TgCDPK1-IN-2

Cat.No: T72081

Target: Parasite

pCDPK1/TgCDPK1-IN-3

Cat.No: T72033

Target: Parasite

Cat.No: T12731

Target: RIP kinase

CpCDPK1/TgCDPK1-IN-1

Cat.No: T78605

Target: Bcr-Abl, Src

Anti-Mouse NK1.1 Antibody (PK136)

Cat.No: T78268

Cat.No: T9017

Synonym: Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2

Target: Others, FLT, Src

Cat.No: T7897

Target: Others, Antibacterial

Cat.No: T12730

Target: RIP kinase

Cat.No: T9470

Target: MAPK

Cat.No: T11943

Target: p38 MAPK

Cat.No: T40350

Synonym: HPK1-IN-4

Target: MAPK

Cat.No: T79790

Target: NF-κB

Cat.No: T60862

Cat.No: T39709

Synonym: HPK1-IN-19

Cat.No: T62628

Cat.No: T72052

Cat.No: T12729

Target: Others

Cat.No: T62742

Cat.No: T78688

Cat.No: T16547

Target: Others

Cat.No: T62723

Cat.No: T78852

Cat.No: T79787

Cat.No: T61887

Cat.No: T72036

Target: Others

Cat.No: T63176

Cat.No: T79788

Cat.No: T60973

Cat.No: T73186

Cat.No: T63541

Cat.No: T63469

Cat.No: T63270

(R)-N-Desmethyl PK11195

Cat.No: T29258

Synonym: (R)-N-Desmethyl PK 11195,(R)-N-Desmethyl PK-11195,(R)-N Desmethyl PK11195,(R) N-Desmethyl PK11195

Cat.No: T61449

Cat.No: T81268

Target: RIP kinase

Cat.No: T73149

Cat.No: T62800

Cat.No: T63659

Cat.No: T62632

Cat.No: T62927

Cat.No: T64064

Cat.No: T62629

Cat.No: T62315

Cat.No: T63046

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02945	Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His) PK1,EGVEGF,PRK1,prokineticin ...	Human	Baculovirus Insect Cells
	EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) i...
TMPY-04765	PKLR Protein, Human, Recombinant (His) PKRL,PKR,RPK,PKL,PK<...	Human	E. coli
	Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pathway and the most common cause of hereditary nonspherocytic hemolytic anemia. Over 250 PKLR-gene mutations have been described, including missense/nonsense, splicing and regulatory mutations, small insertions, small and gross deletions, causing PKD and hemolytic anemia of variabl...
TMPY-04567	SRPK1 Protein, Human, Recombinant (His & GST) SRSF protein kinase 1,SFRSK1,RP3-422H1...	Human	Baculovirus Insect Cells
	Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Isoform 2 of SRPK1 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 of SRPK1 is only seen in th...
TMPH-02786	MAPK14 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	MAPK14 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.6 kDa and the accession number is P47811.
TMPY-04531	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro P38 δ/MAPK13,MAPK13,PRKM...	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPH-02964	UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9DBP5.
TMPY-04551	p38 delta/MAPK13 Protein, Human, Recombinant (GST) MAPK13,p38δ,PRKM13,MAPK-...	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPH-03631	CDPK1 Protein, Toxoplasma gondii, Recombinant (His) Calmodulin-domain protein kinase 1,CDPK	Toxoplasma gondii	E. coli
	N/A. CDPK1 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 63.3 kDa and the accession number is Q9BJF5.
TMPY-04430	p38 gamma/MAPK12 Protein, Human, Recombinant mitogen-activated protein kinase 12,SAPK-3...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
TMPY-04417	DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST) DAPK,death-associated protein kinase 1,ROC...	Human	Baculovirus Insect Cells
	Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK1 contains tenANK repeats, onedeath domain and oneprotein kinase domain. DAPK1 is a calcium / calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. DAPK1 gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 g...
TMPY-04429	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) ERK3,SAPK3,PRKM12,ERK6,P38γ,P38GAMMA,mitog...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cyt...	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi...
TMPH-02007	RIPK1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	RIPK1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.4 kDa and the accession number is Q13546.
TMPH-01639	MAPK1IP1L Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	N/A. MAPK1IP1L Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q8NDC0.
TMPH-00922	ALPK1 Protein, Human, Recombinant (His & Myc) KIAA1527,Lymphocyte alpha-protein kinase,Alpha-prot...	Human	Baculovirus Insect Cells
	ALPK1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-04773	TPK1 Protein, Human, Recombinant (His) THMD5,PP20,HTPK1,thiamin pyrophosphokinase...	Human	E. coli
	Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.
TMPH-02876	RIPK1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold functions regulating inflammatory signaling and cell survival. Has kinase-independent scaffold functions: upon binding of TNF to TNFR1, RIPK1 is recruited to the TNF-R1 signaling complex (TNF-RSC also known as complex I) where it acts as a scaffold protein promoting cell survival, i...
TMPY-04478	IP6K1/IHPK1 Protein, Human, Recombinant (His & GST) inositol hexakisphosphate kinase 1,IHPK	Human	Baculovirus Insect Cells
	IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth-suppressive and...

重组蛋白

Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

Cat.No: TMPY-02945

Species: Human

Expression System: Baculovirus Insect Cells

PKLR Protein, Human, Recombinant (His)

Cat.No: TMPY-04765

Species: Human

Expression System: E. coli

SRPK1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04567

Species: Human

Expression System: Baculovirus Insect Cells

MAPK14 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02786

Species: Mouse

Expression System: E. coli

p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro

Cat.No: TMPY-04531

Species: Human

Expression System: Baculovirus Insect Cells

UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02964

Species: Mouse

Expression System: E. coli

p38 delta/MAPK13 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04551

Species: Human

Expression System: Baculovirus Insect Cells

CDPK1 Protein, Toxoplasma gondii, Recombinant (His)

Cat.No: TMPH-03631

Species: Toxoplasma gondii

Expression System: E. coli

p38 gamma/MAPK12 Protein, Human, Recombinant

Cat.No: TMPY-04430

Species: Human

Expression System: Baculovirus Insect Cells

DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

Cat.No: TMPY-04417

Species: Human

Expression System: Baculovirus Insect Cells

p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04429

Species: Human

Expression System: Baculovirus Insect Cells

UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04480

Species: Human

Expression System: Baculovirus Insect Cells

RIPK1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02007

Species: Human

Expression System: E. coli

MAPK1IP1L Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01639

Species: Human

Expression System: HEK293 Cells

ALPK1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00922

Species: Human

Expression System: Baculovirus Insect Cells

TPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04773

Species: Human

Expression System: E. coli

RIPK1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02876

Species: Mouse

Expression System: E. coli

IP6K1/IHPK1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04478

Species: Human

Expression System: Baculovirus Insect Cells

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