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Search Results for " ifn-α "

Targets Recommended: Others IFNAR

42

抑制剂 & 化合物

3

天然产物

38

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11630	IFN alpha-IFNAR-IN-1 hydrochloride	Others; IFNAR	Immunology/Inflammation; Others
	IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应，IC50 为 2-8 μM。
TP1117	IFN-α Receptor Recognition Peptide 1 IRRP1
	IFN-α Receptor Recognition Peptide 1 is a peptide of IFN-α associated with receptor interactions.
T12933	SM-276001	TLR; COX	Immunology/Inflammation; Neuroscience
	SM-276001 是可口服的干扰素诱导剂，是选择性TLR7激动剂，可以诱导抗肿瘤免疫反应。
T8692	(Rac)-Benpyrine	TNF	Apoptosis
	(Rac)-Benpyrine 是一种有效且具有口服活性的 TNF-α 抑制剂，是Benpyrine 的外消旋体。它可研究TNF-α介导的炎症和自身免疫性疾病。
T1781	GW9508 GW 9508	GPR; Potassium Channel	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel
	GW 9508 是一种选择性 G 蛋白偶联受体FFA1(GPR40) 和GPR120激动剂。它是一种葡萄糖敏感性胰岛素促分泌剂和 ATP 敏感性钾通道开放剂，具有抗炎和抗动脉粥样硬化活性。
T11630L	IFN alpha-IFNAR-IN-1	Others	Others
	IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50: 2-8 μM).
T76637	IFN-γ Antagonist 1
	IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI)，一种干扰素γ (IFN-γ) 拮抗剂，通过抑制IC50约为35 μM的IFN-γ诱导的HLR/DR抗原在Colo 205细胞上的表达展现作用。该化合物在免疫调节领域具有潜在应用。
T76638	IFN-γ Antagonist 1 acetate
	IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate 作为一种干扰素 γ (IFN-γ) 拮抗剂，能够在 Colo 205 细胞中抑制 IFN-γ诱导的 HLR/DR 抗原表达，其 IC50 值约为 35 μM，显示出在免疫调节中的潜在应用价值。
T0867	Bufexamac Bufexamic acid,丁苯羟酸	COX; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience
	Bufexamac (Bufexamic acid) 是 HDAC6 和 HDAC10 的抑制剂，也是一种COX 抑制剂，用于释放 IFN-α，具有抗炎、镇痛和解热作用。
T4403	AX-024 hydrochloride AX-024 HCl	IL Receptor; TNF; COX; IFNAR; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience
	AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂，可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂，可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导，具有低毒、高效和高选择性的特点。
T13063	T6167923	MyD88	Immunology/Inflammation
	T6167923是一种有效的、选择性的MyD88依赖性信号通路抑制剂。T6167923 与 MyD88 的 Toll/IL1 受体 (TIR) 结构域结合良好，破坏 MyD88 的同二聚体形成。T6167923 抑制 NF-κB 驱动的葡萄球菌肠毒素AP (SEAP) 活性，并且改善抗炎活性，对 IFN-γ，IL-1β，IL-6 和 TNF-α 的 IC50分别为 2.7 μM，2.9 μM，2.66 μM 和 2.66 μM。
T64280	ODN 2216
	ODN 2216 是一种 TLR9 (toll-like receptor 9) 配体或激动剂，能够诱导产生大量的 IFN-α 和 IFN-β。ODN 2216 可以利用 pDC (浆细胞样 DC) 诱导 IFN-α，以及利用 DC (树突状细胞) 产生IL-12 (p40)。ODN 2216 能够间接的、在 IFN-α/β 介导下刺激外周血单核细胞 (PBMC) 产生 IFN-γ。ODN 2216 可以激活 NK 细胞，诱导 IFN-γ 产生 TCR 触发的 CD4+T 细胞。
T81259	Rontalizumab RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody
	Rontalizumab为针对IFN-α的人源化IgG1型单克隆抗体，适用于系统性红斑狼疮研究领域。
T64278	ODN 2088
	ODN 2088 是一种 TLR3、TLR7 和 TLR9 的有效抑制剂，无细胞毒性，对 IFN-α 和 IL-6 的释放表现出抑制作用。
T76853	Ropeginterferon alfa-2b
	Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) 为单聚乙二醇化IFN-α类化合物，主要应用于骨髓增性肿瘤研究领域。
T83152	AJ2-71
	AJ2-71为SLC15A4抑制剂，具有抑制IFN-α产生的能力，并能阻断SLC15A4介导的MDP转运，适用于炎症研究。
T64279	ODN 21158
	ODN 21158 是一种 G 修饰的 TLR3 和 TLR9 的有效抑制剂，无细胞毒性。ODN 21158 能够剂量依赖性地抑制 IFN-α 分泌。
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur...
T69898	NG25 trihydrochloride
	NG25 trihydrochloride is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38α. NG 25 prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in a concentration...
T74908	ODN 2336
	ODN 2336 是 A 类 CpG ODN（寡脱氧核苷酸），是一种有效的 TLR9激动剂。ODN 2336 诱导 IFN-α 的产生。ODN 2336 上调 IP-10 mRNA 和 IL-18mRNA 的表达。ODN 2336 可用作疫苗的佐剂。
T72017	6(5H)-Phenanthridinone
	6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimenta...
T60266	(Rac)-Indoximod
	(Rac)-Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO). Combined treatment with IFN-γ and (Rac)-Indoximod significantly suppresses the activity of α-SMA-expressing human cardiac myofibroblasts (hCMs) and promotes apoptosis by up-regulating the genes IRF-1, Fas, and FasL. Moreover, this co-treatment effectively improves cardiac fibrosis[1].
T74913	ODN 6016
	ODN 6016 是一种 CpG-A 寡核苷酸。ODN 6016 可诱导IFN-α产生，可用于研究免疫紊乱，包括HIV-1引起的免疫缺陷。ODN 6016 序列：T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G。
T78508	Delmitide acetate RDP-58 acetate	IFNAR	Immunology/Inflammation
	Delmitide acetate (RDP58) 是一种 d-异构体十肽，具有抗炎活性和口服活性。该化合物能够抑制 TNF-α、IFN-γ 以及白细胞介素 (IL)-12 的生成，同时提高血红素加氧酶 1 的活性，可用于针对溃疡性结肠炎的研究。
T74910	ODN 24888
	ODN 24888 是一种鸟嘌呤修饰的抑制性寡核苷酸 (INH-ODN)，对TLR7/TLR9介导的信号通路表现出强烈的抑制作用。ODN 24888 损害 IFN-α 水平和NF-κB 激活，抑制IL-6的释放。ODN 24888 参与免疫和炎症应答，可作为疫苗佐剂使用。
T75092	STING agonist-24
	STINGagonist-24 (CF504) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING，增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T74911	ODN 24987
	ODN 24987，一种鸟嘌呤修饰的抑制性寡核苷酸（ODN），作用于TLR9，能够抑制IL-6和IFN-α的释放，适用于免疫紊乱研究。ODN 24987 序列为5’-C-C-T-G-G-C-c7G-G-G-G-3’。
T74907	ODN 21595
	ODN 21595是一种鸟嘌呤修饰的抑制性寡核苷酸(INH-ODN)。该化合物能够抑制IFN-α和IL-6的释放，同时不具有细胞毒性。它还能降低CD86与HLA-DR的表达，显示出对于研究系统性红斑狼疮(SLE)具有潜力。
T78953	SIMR3030	SARS-CoV	Microbiology/Virology
	SIMR3030为一有效的SARS-CoV-2 PLpro抑制剂，具有0.0399 µg/mL的IC50值。该化合物展现出抗病毒活性，能够抑制SARS-CoVspike、ORF1b、IFN-α、IL-6 mRNA的表达，并在小鼠中显示良好的安全性。
T74915	ODN D-SL03
	ODN D-SL03是C类CpG寡核苷酸，能诱导PBMCs产生高水平IFN-α，激活人B细胞、NK细胞和单个核细胞，同时上调PBMCs亚群表面CD80、CD86和HLA-DR的表达，还能抑制肿瘤生长。ODN D-SL03序列：5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'。
T75093	STING agonist-25
	STINGagonist-25 (CF505) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING，增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T75096	STING agonist-28
	STINGagonist-28 (CF510) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING，增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T75094	STING agonist-26
	STINGagonist-26 (CF508) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING，增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T36779	NG 25 (hydrochloride hydrate)
	NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38α (IC50s = 56.4, 82.3, and 102 nM, respectively). NG 25 (100 nM) prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectiv...
T75091	STING agonist-23
	STINGagonist-23 (CF502) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING，增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中 IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和 CCL-5的水平。STINGagonist-23 表现出抗 SARS-CoV 系列的活性。
T38161	STING Agonist C11 STING Agonist C11
	STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses gro...
T76945	Cetrelimab
	Cetrelimab (JNJ 63723283; JNJ 3283) 为人源化IgG4κ单克隆抗体，专门针对PD-1。其与PD-1的结合Kd值为1.72 nM（在HEK293细胞中测得）。Cetrelimab有效阻断PD-1与其配体PD-L1和PD-L2的结合，其IC50值分别为111.7 ng/mL与138.6 ng/mL。此外，Cetrelimab能激活外周T细胞，提升细胞因子（IFN-γ, IL-2, TNF-α）的表达水平，进而抑制肿瘤在体内的生长。
T61071	AX-024
	AX-024 is a novel chemical compound that acts as an orally available inhibitor of the TCR-Nck interaction. Its primary mechanism of action is the selective inhibition of T cell activation triggered by TCR stimulation. With an IC50 value of approximately 1 nM, AX-024 effectively modulates cell signaling by specifically targeting SH3 domains. Additionally, AX-024 demonstrates desirable characteristics such as low acute toxicity, high potency, and excellent selectivity. Notably, it exhibits strong ...
T11482	GSK2245035	Others	Others
	GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood
T83700	IRBP (651-670) (human) TFA IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)
	IRBP651-670（Interphotoreceptor retinoid-binding protein (651-670)）是IRBP（亦称为retinoid-binding protein 3）的肽段，参与色素再生，通过将视黄醇和视黄醛从光感受细胞传输到视网膜色素上皮。在C57BL/6小鼠中，利用IRBP651-670诱导自身免疫性葡萄膜炎，这些小鼠携带H-2b单体型。用IRBP651-670（300 µg/动物）免疫增加了小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平，免疫细胞浸润及光感受器损伤。
T36486	Benpyrine
	Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1]. Benpyrine (5-20 μM; 14 hours; RAW264.7 cells) pretreatment results in a dose-dependent decrease in the phosphorylation of IκBα in RAW264.7 cells (stimulated with 10 ng/mL TNF-α or 1 μg/mL LPS). Benpyrine abo...
T13234	Tyk2-IN-5	Others	Others
	Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).

化合物

IFN alpha-IFNAR-IN-1 hydrochloride

Cat.No: T11630

Target: Others, IFNAR

IFN-α Receptor Recognition Peptide 1

Cat.No: TP1117

Synonym: IRRP1

Cat.No: T12933

Target: TLR, COX

(Rac)-Benpyrine

Cat.No: T8692

Target: TNF

Cat.No: T1781

Synonym: GW 9508

Target: GPR, Potassium Channel

IFN alpha-IFNAR-IN-1

Cat.No: T11630L

Target: Others

IFN-γ Antagonist 1

Cat.No: T76637

IFN-γ Antagonist 1 acetate

Cat.No: T76638

Cat.No: T0867

Synonym: Bufexamic acid,丁苯羟酸

Target: COX, HDAC

AX-024 hydrochloride

Cat.No: T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

Cat.No: T13063

Target: MyD88

Cat.No: T64280

Cat.No: T81259

Synonym: RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody

Cat.No: T64278

Ropeginterferon alfa-2b

Cat.No: T76853

Cat.No: T83152

Cat.No: T64279

Cat.No: T38008

NG25 trihydrochloride

Cat.No: T69898

Cat.No: T74908

6(5H)-Phenanthridinone

Cat.No: T72017

(Rac)-Indoximod

Cat.No: T60266

Cat.No: T74913

Delmitide acetate

Cat.No: T78508

Synonym: RDP-58 acetate

Target: IFNAR

Cat.No: T74910

STING agonist-24

Cat.No: T75092

Cat.No: T74911

Cat.No: T74907

Cat.No: T78953

Target: SARS-CoV

Cat.No: T74915

STING agonist-25

Cat.No: T75093

STING agonist-28

Cat.No: T75096

STING agonist-26

Cat.No: T75094

NG 25 (hydrochloride hydrate)

Cat.No: T36779

STING agonist-23

Cat.No: T75091

STING Agonist C11

Cat.No: T38161

Synonym: STING Agonist C11

Cat.No: T76945

Cat.No: T61071

Cat.No: T11482

Target: Others

IRBP (651-670) (human) TFA

Cat.No: T83700

Synonym: IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)

Cat.No: T36486

Cat.No: T13234

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2539	1beta-Hydroxyalantolactone	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	1beta-Hydroxyalantolactone 是从药用植物大英花的花头中分离出的小分子化合物，可抑制细胞中TNF-α、IL-17、IFN-γ的表达，促进TNF-α、IFN-γ、IL-17的分泌，可防治类风湿性关节炎。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
TN6366	Lupinalbin A 鲁冰花
	Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokines and blocking of IFN-β/STAT1 pathw

天然产物

1beta-Hydroxyalantolactone

Cat.No: TN2539

Target: IL Receptor, TNF

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: TN6366

Synonym: 鲁冰花

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated IFN-R,interferon (α, β and Ω) receptor 2,<...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-04578	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) Interferon α1,IFN-alphaD,IFN-...	Human	P. pastoris (Yeast)
	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.
TMPJ-00746	IFN-alpha 2b/IFNA2 Protein, Human, Recombinant 干扰素,IFNA2,Interferon α-2,Interferon α<...	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the ca...
TMPY-00638	Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) IFN-αB,IFN-alphaB,interferon,	Human	HEK293 Cells
	Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is A0A7R8C381.
TMPJ-00745	IFN-alpha 2a/IFNA2 Protein, Human, Recombinant Interferon α-2,IFNA2,干扰素,IFN ...	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-ter...
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His) interferon (alpha, beta and omega) receptor 1,IFN-<...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPY-02515	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) IFN-alphaJ,干扰素,IFNA-J,IFN-α	Human	HEK293 Cells
	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P01567.
TMPY-02566	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) 干扰素,interferon, α4,MGC142200,interferon, alpha 4,IN...	Human	Baculovirus Insect Cells
	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is P05014.
TMPY-00265	Interferon alpha 2/IFNA2 Protein, Human, Recombinant IFNAB,干扰素,IFNA2B,IFN-alphaA,INFA2...	Human	P. pastoris (Yeast)
	Interferon alpha 2/IFNA2 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 19.3 kDa and the accession number is P01563.1.
TMPY-00830	interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc) IFN-α,INFA5,interferon, alpha 5,IFN	Human	HEK293 Cells
	interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.3 kDa and the accession number is A0A7R8C382.
TMPK-00342	IFNAR1 Protein, Mouse, Recombinant (His & Avi) IFN-α-REC,IFN-R-1,IFNAR1...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is P33896.
TMPK-00325	IFNAR1 Protein, Human, Recombinant (His & Avi) AVP,IFN-alpha-REC,IFN-α/β R1,...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00343	IFNAR1 Protein, Mouse, Recombinant (hFc) AVP,IFNBR,IFN-alpha/β R1,IFNAR,	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
TMPK-00326	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated IFN-alpha/β R1,IFN-α/β R1,IFN...	Human	HEK293 Cells
	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00637	IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) β receptor10,IFNbR2,IFN α/β R2,	Cynomolgus	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-...
TMPY-04855	interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) leIF G,IFN-alpha,interferon-α,INA5,IFN...	Human	P. pastoris (Yeast)
	interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.1 kDa and the accession number is A0A7R8C382.
TMPK-00075	IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) IFN-α-1/13,IFN α1,IF...	Human	HEK293 Cells
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.14 kDa and the accession number is P01562.
TMPK-00074	IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) IFN-α-1/13,IFN alpha1,干扰素,Interfe...	Mouse	HEK293 Cells
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.88 kDa and the accession number is P01572.
TMPK-00889	IFNAR2 Protein, Human, Recombinant (aa 27-243, His) IFN-alpha/beta R2,IFNAR2,IFNbR2,<...	Human	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t...
TMPY-03648	Interferon alpha B/IFNA8 Protein, Human, Recombinant IFN-αB,IFN-alphaB,interferon, alp...	Human	HEK293 Cells
	Interferon alpha B/IFNA8 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38 kDa and the accession number is A0A7R8C381.
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His) IFNARB,IFNABR,interferon (α, β an...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc) interferon (α, β and ω) receptor 2,IFNABR,...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPJ-00747	IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant IFN-Alpha-2,Interferon α-A,IFN	Mouse	E. coli
	At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carbo...
TMPJ-00780	IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His) Interferon α-K,Interferon α-6,IFN...	Human	HEK293 Cells
	Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPY-02634	IFNAR1 Protein, Human, Recombinant (hFc) interferon (α, β and Ω) receptor 1,IFNBR,A...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPJ-00331	IFNAR1 Protein, Rhesus macaque, Recombinant (His) IFN-al,CRF2-1,IFN-alpha/beta receptor 1,hu...	Rhesus	HEK293 Cells
	Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPY-04841	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His) interferon, alpha 7,interferon, α7,IFN-	Human	P. pastoris (Yeast)
	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A7R8C383.
TMPY-00829	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) interferon, α4,IFN-α4a,干扰素,interf...	Human	HEK293 Cells
	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is P05014.
TMPY-02516	Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc) interferon, α10,interferon, alpha 10,IFN-a...	Human	HEK293 Cells
	Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen...
TMPY-06407	Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) IFN-αA,INFA2,干扰素,Interferon α2,	Human	HEK293 Cells
	Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.29 kDa and the accession number is P01563-1.
TMPY-02347	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) interferon, alpha 13,RP23-139P14.1,IFN-α 1...	Mouse	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.5 kDa and the accession number is Q80SU4.
TMPY-03891	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) IFN-α 13,干扰素,interferon, alpha 13,interfer...	Mouse	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q80SU4.
TMPY-03320	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) IFN-α 13,干扰素,interferon, alpha 13,IFN<...	Cynomolgus	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFW4.
TMPY-03375	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) IFNA13,干扰素,interferon, α13,interferon, alp...	Cynomolgus	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is G7NFW4.
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli) Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干...	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ...
TMPJ-01371	Limitin Protein, Mouse, Recombinant (His) Ifnz,Lmtn,IFN-z,IFN-ζ,BGIF,interf...	Mouse	HEK293 Cells
	Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of ...
TMPY-02549	GBP1 Protein, Human, Recombinant (His) guanylate binding protein 1,GBP1	Human	HEK293 Cells
	Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secre...
TMPJ-00177	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated BAFF,Dendritic cell-derived TNF-like molecule,CD257,B lympho...	Human	HEK293 Cells
	B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymor...

重组蛋白

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04799

Species: Human

Expression System: HEK293 Cells

Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04578

Species: Human

Expression System: P. pastoris (Yeast)

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

Cat.No: TMPJ-00746

Species: Human

Expression System: E. coli

Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)

Cat.No: TMPY-00638

Species: Human

Expression System: HEK293 Cells

IFN-alpha 2a/IFNA2 Protein, Human, Recombinant

Cat.No: TMPJ-00745

Species: Human

Expression System: E. coli

IFNAR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02647

Species: Human

Expression System: HEK293 Cells

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02515

Species: Human

Expression System: HEK293 Cells

Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02566

Species: Human

Expression System: Baculovirus Insect Cells

Interferon alpha 2/IFNA2 Protein, Human, Recombinant

Cat.No: TMPY-00265

Species: Human

Expression System: P. pastoris (Yeast)

interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00830

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00342

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00325

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00343

Species: Mouse

Expression System: HEK293 Cells

IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00326

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)

Cat.No: TMPK-00637

Species: Cynomolgus

Expression System: HEK293 Cells

interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)

Cat.No: TMPY-04855

Species: Human

Expression System: P. pastoris (Yeast)

IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00075

Species: Human

Expression System: HEK293 Cells

IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00074

Species: Mouse

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (aa 27-243, His)

Cat.No: TMPK-00889

Species: Human

Expression System: HEK293 Cells

Interferon alpha B/IFNA8 Protein, Human, Recombinant

Cat.No: TMPY-03648

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01642

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01640

Species: Human

Expression System: HEK293 Cells

IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant

Cat.No: TMPJ-00747

Species: Mouse

Expression System: E. coli

IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00780

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02634

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00331

Species: Rhesus

Expression System: HEK293 Cells

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)

Cat.No: TMPY-04841

Species: Human

Expression System: P. pastoris (Yeast)

Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00829

Species: Human

Expression System: HEK293 Cells

Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02516

Species: Human

Expression System: HEK293 Cells

Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06407

Species: Human

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02347

Species: Mouse

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03891

Species: Mouse

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03320

Species: Cynomolgus

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03375

Species: Cynomolgus

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (E. coli)

Cat.No: TMPY-06983

Species: Human

Expression System: E. coli

Limitin Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01371

Species: Mouse

Expression System: HEK293 Cells

GBP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02549

Species: Human

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated

Cat.No: TMPJ-00177

Species: Human

Expression System: HEK293 Cells

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