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Cat. No.	Product Name	Target	Signaling Pathways
TQ0091	LY2795050	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	LY2795050 是一种新型特异性 κ-阿片受体拮抗剂，IC50为0.72 nM。
T21620	Adenosine receptor antagonist 4	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Adenosine receptor antagonist 4 是一种腺苷受体拮抗剂。
T78646	Estrogen receptor antagonist 8	Estrogen Receptor/ERR	Endocrinology/Hormones
	Estrogen receptor antagonist8 作为一种雌激素受体ER的有效拮抗剂，在体内展现出抗子宫活性（EC50=4.160 μM）。
TP1422	Interleukin (IL)-6 Receptor	Others	Others
	Interleukin (IL)-6 Receptor 是一种肽，来源于白细胞介素6受体。
T3177	Orexin 2 Receptor Agonist OX2R	OX Receptor	GPCR/G Protein; Neuroscience
	Orexin 2 Receptor Agonist (OX2R) 是一种选择性有效的OX2R 激动剂， EC50为23 nM。
T11349	GABAA receptor agent 1	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	GABAA receptor agent 1 是GABAA 受体的高亲和力配体，有抗惊厥活性。
T9244	σ1 Receptor antagonist-1	Sigma receptor	GPCR/G Protein
	σ1 Receptor antagonist-1 是高选择性的 sigma 1受体拮抗剂，pKi 为10.28。它抑制细胞生长，在 G0/G1 期阻滞细胞周期并诱导 MCF-7/ADR 细胞凋亡。
T9247	Vanilloid receptor antagonist 1 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile	TRP/TRPV Channel	Membrane transporter/Ion channel
	Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) 是香草酸受体的有效拮抗剂。
T5586	cFMS Receptor Inhibitor II	c-Fms	Tyrosine Kinase/Adaptors
	cFMS Receptor Inhibitor II 是 CSF-1R 激酶抑制剂。其中 CSF-1 是细胞因子。
T37792	A2A receptor antagonist 1 CPI-444 analog,A2A receptor antagonist 1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2A receptor antagonist 1 (CPI-444 analog)是腺苷 A2A 和 A1受体的拮抗剂，Ki 值分别为4和264 nM。
T12912	Sigma-1 receptor antagonist 3	Sigma receptor; HER	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Sigma-1 receptor antagonist 3 是 Sigma-1受体选择性拮抗剂，Ki 为 1.14 nM。它抑制 hERG，IC50为 1.54μM。它在神经性疼痛方面有研究的价值。
T4312	GPR120 Agonist 2 GPR120 receptor agonist	GPR	Endocrinology/Hormones; GPCR/G Protein
	GPR120 Agonist 2 是一种选择性 GPR120激动剂。
T37734	AMPA receptor modulator-2	GluR	Neuroscience
	AMPA receptor modulator-2 是 AMPA 受体的有效调节剂，在 TARPγ2 依赖性 AMPA 受体上的pIC50为 10.1。
T13736	Interferon receptor inducer-1	IFNAR	Immunology/Inflammation
	Interferon receptor inducer-1 是一种干扰素(IFN)受体诱导剂，可用于干扰素诱导参与的紊乱性疾病的研究。
T10058	A2B receptor antagonist 1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2B receptor antagonist 1 是一个有效的 A2B 腺苷受体 (A2B adenosine receptor) 拮抗剂。
T12911	Sigma-1 receptor antagonist 2	Sigma receptor	GPCR/G Protein
	Sigma-1 receptor antagonist 2 是有效的sigma 1受体选择性拮抗剂，与 σ1 和 σ2 受体结合的Ki 分别为 3.88 和 1288 nM。
T12910	Sigma-1 receptor antagonist 1	Sigma receptor	GPCR/G Protein
	Sigma-1 receptor antagonist 1 是一种有效、特异性的 sigma-1 受体拮抗剂。 Sigma-1 receptor antagonist 1 具有抗神经性疼痛活性，可用于治疗神经性疼痛研究。
T11211	EP4 receptor antagonist 1	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	EP4 receptor antagonist 1 是一种有效的特异性前列腺素 EP4受体拮抗剂，对人和小鼠 EP4受体的 IC50分别为6.1 nM 和16.2 nM。 EP4 receptor antagonist 1 可用于癌症免疫治疗的研究。
T5829	H4 Receptor antagonist 1	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	H4 Receptor antagonist 1 是选择性组胺 H4受体反向激动剂，其IC50值为19 nM。
T10250	ADRA1D receptor antagonist 1 HCl ADRA1D receptor antagonist 1 HCl（1191908-24-3 free base）	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	ADRA1D receptor antagonist 1 HCl 是一种具有口服活性、高效性和选择性的 α1D 肾上腺素受体拮抗剂（Ki：1.6 nM），具有潜在的抗增殖活性。
TP1704	Galanin Receptor Ligand M35 TFA	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Galanin Receptor Ligand M35 TFA(142846-71-7 free base) 是一种高亲和力配体和甘丙肽受体拮抗剂 (Kd=0.1 nM)。
T22466	Adenosine receptor A1 antagonist 5	cAMP	GPCR/G Protein
	Adenosine receptor A1 antagonist 5 可作为一种腺苷拮抗剂，是一种氧嘌呤，可作为杀虫剂和虫害防治剂，对血压升高有抑制作用。
T4521	Edg-2 receptor inhibitor 1 SAR-100842	LPA Receptor	GPCR/G Protein
	Edg-2 receptor inhibitor 1 (SAR-100842) 是一种提取的 Edg-2 受体抑制剂 (IC50: <0.1 μM)。
T9579L	GLP-1 receptor agonist 9 citrate GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base)	Glucagon Receptor	GPCR/G Protein
	GLP-1 receptor agonist 9 citrate 是 GLP-1 的激动剂。
T4031	S1p receptor agonist 1 S1p-receptor-agonist-1	S1P Receptor; LPL Receptor	GPCR/G Protein
	S1p receptor agonist 1 (S1p-receptor-agonist-1) 是有口服活性的S1P 受体激动剂，具有诱导 S1P1 内化的活性，EC50为9.83 nM。它有潜力用于关节炎和实验性自身免疫性脑炎)的相关研究。
T14127	Adenosine A1 receptor activator T62	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Adenosine A1 receptor activator T62 是腺苷 A1 受体的变构增强剂，有镇痛作用。
T60075	Dopamine D2 receptor agonist-2 Dopamine D2 Receptor	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) 是靶向多巴胺D2受体的配体。
T38836L	Protease-Activated Receptor-1, PAR-1 Agonist acetate	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-1, PAR-1 Agonist acetate 是一种选择性蛋白酶激活受体 1 (PAR-1) 激动剂肽。它对应于 PAR1 栓系配体，可以选择性地模拟凝血酶通过该受体的作用。
T61901	σ1 Receptor/μ Opioid receptor modulator 1
	σ1 Receptor/μ Opioid receptor modulator 1 (Compound 44) 是一种有效的σ1受体拮抗剂（Ki= 1.86 nM）和μ阿片受体激动剂（Ki=2.1 nM）。σ1 Receptor/μ Opioid receptor modulator 1 具体有效的镇痛活性，可用于神经性疼痛的研究。
T39587	APJ receptor agonist 4
	APJ Receptor Agonist 4 is a potent, orally active apelin receptor (APJ) agonist, demonstrating an EC50 of 0.06 nM and a Ki of 0.07 nM. It exhibits excellent pharmacokinetic profiles in rodent heart failure (HF) models and has shown an acceptable safety profile in preclinical toxicology studies. This compound effectively improves cardiac function, making it valuable for research into HF disease.
T38139	Orexin receptor antagonist 2
	Orexin Receptor Antagonist 2 (compound 30), characterized by its potent antagonistic activity with pKis of 7.69 and 9.78, holds promise for insomnia research[1].
T40307	Adenosine receptor antagonist 1
	Adenosine receptor antagonist 1 is a highly selective antagonist for the A2aR adenosine receptor, exhibiting an IC50 value of 0.29 nM. It demonstrates a remarkable 14-fold selectivity towards the A2aR receptor in comparison to the A2bR receptor.
T37223	Glucagon Receptor Antagonist I
	Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.
T40697	Glucocorticoids receptor agonist 2
	Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflammatory properties without disrupting insulin secretion.
T40808	Glucocorticoids receptor agonist 1
	Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining insulin secretion function.
T40893	Estrogen receptor modulator 6
	Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for ERβ over ERα, as evidenced by its affinity (K i = 8.4 nM).
T39813	APJ receptor agonist 1
	APJ receptor agonist 1, a potent biphenyl acid derivative, acts as an agonist (EC50 of 0.093 nM and 0.12 nM for human and rat APJ receptors, respectively) for the APJ receptor (APJ-R). It exhibits significant in vitro potency towards apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 holds promise for heart failure research.
T40999	NMDA receptor antagonist 2
	NMDA receptor antagonist 2 is a highly potent and orally active NR2B subtype-selective antagonist of the N-methyl-D-aspartate (NMDA) receptor. It exhibits remarkable binding affinities, with an IC50 of 1.0 nM and a Ki value of 0.88 nM. This compound finds valuable application in scientific investigations focusing on neuropathic pain and Parkinson’s disease.
T36580	Glucagon Receptor Antagonist Inactive Control
	Glucagon Receptor Antagonist Inactive Control 是一种 Glucagon 受体拮抗剂，可用于生命科学领域的相关研究。其产品编号为 T36580，CAS号为 362482-00-6。
T39561	Orexin 2 Receptor Agonist 2
	Orexin 2 Receptor Agonist 2 (ORA-2) is a specific agonist for the orexin 2 receptor.
T36553	Thrombin Receptor Peptide Ligand (trifluoroacetate salt)
	Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide in vitro when used at a concentration of 32 μM but does not affect platelet aggregation induced by ADP or collagen. It also inhibits thrombin- and TRAP-induced proliferation of vascular smooth muscle cells (VSMCs). Thrombin receptor peptide ligand (100 μmol/kg bolus, i.v...
T80843	Wasabi Receptor Toxin WaTx
	Wasabi Receptor Toxin通过延长TRPA1通道的开放时间并降低其Ca2+渗透性，从而激活该通道。该化合物被应用于急性与持续性疼痛研究领域。
T40234	Ghrelin receptor full agonist-2
	Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.
T38595	EP4 receptor antagonist 3 EP4 receptor antagonist 3
	EP4 receptor antagonist 3 is a highly potent and specific inhibitor of the EP4 receptor. It is intended for research purposes in studying EP4 receptor-mediated diseases such as acute and chronic pain, osteoarthritis, rheumatoid arthritis, and cancer.
T62953	Estrogen receptor antagonist 6
	Estrogen receptor antagonist 6 是一种 Estrogen receptor 的有效拮抗剂。雌激素受体 (Estrogen receptor) 是一种配体激活的转录调节蛋白，能够与内源性雌激素的相互作用，并介导多种生物效应的诱导。Estrogen receptor antagonist 6 具有潜力进行转移性疾病的研究。
T60842	GABAA receptor agonist 1
	GABAA receptor agonist 1 (compound 3e) 是有效的 GABAA 受体激动剂，它结合在GABAA 受体的 GABAA 结合位点结合以产生 GABA 能效应。GABAA receptor agonist 1 在 FST 和 TST 抑郁症的经典小鼠模型中具有抗抑郁活性，在抑郁症研究中具有潜力。
T62268	μ opioid receptor agonist 1
	μ opioid receptor agonist 1 （Compound H-1a）是一种光学纯的氧杂环取代吡咯并吡唑衍生物，也是一种 MOR 受体激动剂，能够用于研究疼痛及疼痛相关疾病。
T61625	GABAA receptor agonist 2
	GABAA receptor agonist 2 (compound 4c) is a highly potent GABAA receptor agonist which exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, GABAA receptor agonist 2 produces GABAergic effects. Notably, Compound 4c holds promise for depression research [1].
T79430	μ opioid receptor agonist 3	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	μopioid receptor agonist3 (compound 20) 是高效的μOR激动剂，其EC50 值为0.87 nM。该化合物在疼痛和神经精神适应症研究中具备潜在应用价值。
T80512	Thrombin receptor peptide ligand	Thrombin	Proteases/Proteasome
	Thrombin receptor peptide ligand为凝血酶受体的一种拮抗肽，用于抗血栓治疗。

化合物

Cat.No: TQ0091

Target: Opioid Receptor

Adenosine receptor antagonist 4

Cat.No: T21620

Target: Adenosine Receptor

Estrogen receptor antagonist 8

Cat.No: T78646

Target: Estrogen Receptor/ERR

Interleukin (IL)-6 Receptor

Cat.No: TP1422

Target: Others

Orexin 2 Receptor Agonist

Cat.No: T3177

Synonym: OX2R

Target: OX Receptor

GABAA receptor agent 1

Cat.No: T11349

Target: GABA Receptor

σ1 Receptor antagonist-1

Cat.No: T9244

Target: Sigma receptor

Vanilloid receptor antagonist 1

Cat.No: T9247

Synonym: 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile

Target: TRP/TRPV Channel

cFMS Receptor Inhibitor II

Cat.No: T5586

Target: c-Fms

A2A receptor antagonist 1

Cat.No: T37792

Synonym: CPI-444 analog,A2A receptor antagonist 1

Target: Adenosine Receptor

Sigma-1 receptor antagonist 3

Cat.No: T12912

Target: Sigma receptor, HER

GPR120 Agonist 2

Cat.No: T4312

Synonym: GPR120 receptor agonist

Target: GPR

AMPA receptor modulator-2

Cat.No: T37734

Target: GluR

Interferon receptor inducer-1

Cat.No: T13736

Target: IFNAR

A2B receptor antagonist 1

Cat.No: T10058

Target: Adenosine Receptor

Sigma-1 receptor antagonist 2

Cat.No: T12911

Target: Sigma receptor

Sigma-1 receptor antagonist 1

Cat.No: T12910

Target: Sigma receptor

EP4 receptor antagonist 1

Cat.No: T11211

Target: Prostaglandin Receptor

H4 Receptor antagonist 1

Cat.No: T5829

Target: Histamine Receptor

ADRA1D receptor antagonist 1 HCl

Cat.No: T10250

Synonym: ADRA1D receptor antagonist 1 HCl（1191908-24-3 free base）

Target: Adrenergic Receptor

Galanin Receptor Ligand M35 TFA

Cat.No: TP1704

Target: Neuropeptide Y Receptor

Adenosine receptor A1 antagonist 5

Cat.No: T22466

Target: cAMP

Edg-2 receptor inhibitor 1

Cat.No: T4521

Synonym: SAR-100842

Target: LPA Receptor

GLP-1 receptor agonist 9 citrate

Cat.No: T9579L

Synonym: GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base)

Target: Glucagon Receptor

S1p receptor agonist 1

Cat.No: T4031

Synonym: S1p-receptor-agonist-1

Target: S1P Receptor, LPL Receptor

Adenosine A1 receptor activator T62

Cat.No: T14127

Target: Adenosine Receptor

Dopamine D2 receptor agonist-2

Cat.No: T60075

Synonym: Dopamine D2 Receptor

Target: Dopamine Receptor

Protease-Activated Receptor-1, PAR-1 Agonist acetate

Cat.No: T38836L

Target: Protease-activated Receptor

σ1 Receptor/μ Opioid receptor modulator 1

Cat.No: T61901

APJ receptor agonist 4

Cat.No: T39587

Orexin receptor antagonist 2

Cat.No: T38139

Adenosine receptor antagonist 1

Cat.No: T40307

Glucagon Receptor Antagonist I

Cat.No: T37223

Glucocorticoids receptor agonist 2

Cat.No: T40697

Glucocorticoids receptor agonist 1

Cat.No: T40808

Estrogen receptor modulator 6

Cat.No: T40893

APJ receptor agonist 1

Cat.No: T39813

NMDA receptor antagonist 2

Cat.No: T40999

Glucagon Receptor Antagonist Inactive Control

Cat.No: T36580

Orexin 2 Receptor Agonist 2

Cat.No: T39561

Thrombin Receptor Peptide Ligand (trifluoroacetate salt)

Cat.No: T36553

Wasabi Receptor Toxin

Cat.No: T80843

Synonym: WaTx

Ghrelin receptor full agonist-2

Cat.No: T40234

EP4 receptor antagonist 3

Cat.No: T38595

Synonym: EP4 receptor antagonist 3

Estrogen receptor antagonist 6

Cat.No: T62953

GABAA receptor agonist 1

Cat.No: T60842

μ opioid receptor agonist 1

Cat.No: T62268

GABAA receptor agonist 2

Cat.No: T61625

μ opioid receptor agonist 3

Cat.No: T79430

Target: Opioid Receptor

Thrombin receptor peptide ligand

Cat.No: T80512

Target: Thrombin

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