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Search Results for " 病毒灵 "

3

抑制剂 & 化合物

24

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0090	Moroxydine hydrochloride 盐酸吗啉胍,ABOB hydrochloride,病毒灵,Moroxydine HCl	Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Moroxydine hydrochloride (ABOB hydrochloride) 是一种合成的杂环双胍类抗病毒药物。它具有抗病毒活性，有助于预防和治疗流感。
T17026	Tecovirimat ST-246,特考韦瑞	Cysteine Protease	Proteases/Proteasome
	Tecovirimat 是一种核心蛋白半胱氨酸蛋白酶抑制剂，可能用于治疗天花感染。Tecovirimat 是一种新型抗病毒药物，对多种正痘病毒具有有效和选择性的活性（EC50：约 10 nM）。通过靶向病毒 p37 蛋白直系同源物来抑制正痘病毒的排出。迄今为止，Tecovirimat 已在所有小动物和非人类灵长类动物预防和治疗痘病毒引起的疾病模型中显示出功效。
T78455	Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
	Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 是一款钌基化合物，既可作为量子点 (QDs) 荧光猝灭剂，也适用于捕获病毒抗原EV71的探针。此外，该化合物还用于作为灵敏的电致化学发光 (ECL) 试剂，用于基质金属蛋白酶 (MMP)[2] 的检测。

化合物

Moroxydine hydrochloride

Cat.No: T0090

Synonym: 盐酸吗啉胍,ABOB hydrochloride,病毒灵,Moroxydine HCl

Target: Antiviral, Influenza Virus

Cat.No: T17026

Synonym: ST-246,特考韦瑞

Target: Cysteine Protease

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2

Cat.No: T78455

Cat. No.	Product Name	Target	Signaling Pathways
TN1059	Ganoderic acid B	IL Receptor; HIV Protease; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂，抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。
T4S0998	Trifolirhizin 红车轴草根甙/三叶豆紫檀苷,三叶豆紫檀苷	TNF; Tyrosinase	Apoptosis; Proteases/Proteasome
	Trifolirhizin 是一种从苦参根中分离出的 pterocarpan 黄酮类化合物。它具有酪氨酸酶高抑制活性，IC50=506 μM。它具有抗炎和抗癌的潜能。
T1664	Meglutol Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托	Endogenous Metabolite; HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Meglutol (3-Hydroxy-3-methylglutaric acid) 是一种抗血脂剂，可降低胆固醇、甘油三酯、血清 β-脂蛋白和磷脂。它抑制胆固醇生物合成中的限速酶羟甲基戊二酰辅酶 A 还原酶的活性。
T5687	WITHAFERIN A 醉茄素 A,醉茄素A	Ferroptosis; NF-κB	Apoptosis; NF-κB
	Withaferin A 是从南非醉茄中分离到的一种甾体内酯，是内皮蛋白 C 受体脱落抑制剂，可以抑制NF-kB 的活性，具有抗炎，抗肿瘤等作用。它是一种新型 NFkappaB 抑制剂，有望成为治疗各种炎症性疾病和癌症的新型抗炎药。
T2770	Gentiopicroside Gentiopicrin,龙胆苦甙,龙胆苦苷	P450; HCV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Gentiopicroside (Gentiopicrin) 是天然环烯醚萜苷，具有抗炎和抗氧化活性。它抑制P450的活性，对 CYP2A6 的 IC50和 Ki 值分别为 61 µM 和 22.8 µM，
T3233	Sophoricoside Genistein sophoricoside,槐苷	Others	Others
	Sophoricoside (Genistein sophoricoside) 是一种异黄酮糖苷，从槐花中分离得到，具有抗炎，抗癌和免疫抑制作活性。
T2786	Oxysophocarpine 氧化槐树碱,氧卡地平	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Oxysophocarpine 是提取自海藻的生物碱。它抑制口腔鳞状细胞癌的生长和转移。它对中枢神经系统和周围神经系统具有神经保护作用和抗伤害感受作用。
TQ0089	Juglanin	Apoptosis; JNK; Autophagy	Apoptosis; Autophagy; MAPK
	Juglanin 是来自金鸡脚的一种黄酮类天然产物，是一种 JNK 的激活剂，能诱导人乳腺癌细胞的凋亡和自噬，具有炎症和抗肿瘤活性。
T6S0232	Eriodictyol 圣草酚,Huazhongilexone	Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物，具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 18 nM。它可诱导Nrf2信号通路。
TN1108	Kaempferol 3-O-sophoroside 槐角黄酮苷,Kaempferol 3-O-beta-sophoroside,山奈酚-3-O-β-D-槐糖苷	Anti-infection	Microbiology/Virology
	Kaempferol 3-O-sophoroside (Kaempferol 3-O-beta-sophoroside) 是一种 Kaempferol 衍生物，从栽培山参 (Panax ginseng) 的叶子中分离得到，具有抗炎作用。
TN6709	6,7-DIMETHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN	Others	Others
	6,7-DIMETHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN 是一种从毛豆中分离出来的天然产物。
T6S1768	Narcissin 水仙苷,Isorhamnetin 3-Rutinoside,Narcissoside	Antioxidant	oxidation-reduction
	Narcissin (Isorhamnetin 3-Rutinoside) 是一种黄连糖苷，能够清除 ONOO-(IC50:3.5 μM)和 SIN-1 衍生的 ONOO-(IC50:9.6 μM)，具有抗氧化作用。
TN1327	7,22,25-Stigmastatrienol	Others	Others
	7,22,25-Stigmastatrienol is a natural product
TN2223	Soyacerebroside I 大豆脑苷 I	IL Receptor; NOS; COX	Immunology/Inflammation; Neuroscience
	Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity.
TN4515	Melilotigenin C	Others	Others
	Melilotigenin C是一种天然产物，属于豆科草木樨属，其产品编号为 TN4515，CAS号为 188970-21-0。Melilotigenin C可用作对照参考。
T32551	Lamprolobine
	Lamprolobine is a bioactive chemical.
TN4425	Lehmannine Lemannine	Others	Others
	Lehmannine是一种天然产物，属于豆科厚果槐属，其产品编号为 TN4425，CAS号为 58480-54-9。Lehmannine可用作对照参考。
TN1347	8-Prenylkaempferol 去甲脱水淫羊藿黄素	p38 MAPK; NF-κB; PI3K	MAPK; NF-κB; PI3K/Akt/mTOR signaling
	8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and
T2S0118	Daurinoline	Calcium Channel; 5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury. Daurinoline could significantly reverse noradrenaline induced constriction of pial arterioles and venules, and increase the number of blood vessels which were decreased by noradrenaline.
TN5139	Thalifoline	Antifection	Microbiology/Virology
	Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
TN1158	(-)-Sparteine Sparteine,(-)-Lupinidine,鹰爪豆碱	Others	Others
	Sparteine is a natural product
TQ0072	Warangalone Scandenolone,攀登鱼藤异黄酮	PKA	Tyrosine Kinase/Adaptors
	Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively.
TN6686	Cyclo(Pro-Pro)
	Cyclo(Pro-Pro) tasted bitter.Verpacamides A-D, a sequence of C11N5 diketopiperazines relating cyclo(Pro-Pro) to cyclo(Pro-Arg), from the marine sponge Axinella vaceleti is possible biogenetic precursors of pyrrole-2-aminoimidazole alkaloids.
TMA0132	Dihydrophaseic acid	Others	Others
	Dihydrophaseic acid 3'-O-b-D-glucopyranoside (D3G) can increase the proliferation and differentiation of osteoblast cells and enhance bone formation, suggests that D3G may be a good candidate for the treatment of osteoporosis.

天然产物

Ganoderic acid B

Cat.No: TN1059

Target: IL Receptor, HIV Protease, JAK, STAT

Cat.No: T4S0998

Synonym: 红车轴草根甙/三叶豆紫檀苷,三叶豆紫檀苷

Target: TNF, Tyrosinase

Cat.No: T1664

Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托

Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Cat.No: T5687

Synonym: 醉茄素 A,醉茄素A

Target: Ferroptosis, NF-κB

Gentiopicroside

Cat.No: T2770

Synonym: Gentiopicrin,龙胆苦甙,龙胆苦苷

Target: P450, HCV Protease

Cat.No: T3233

Synonym: Genistein sophoricoside,槐苷

Target: Others

Oxysophocarpine

Cat.No: T2786

Synonym: 氧化槐树碱,氧卡地平

Target: Prostaglandin Receptor

Cat.No: TQ0089

Target: Apoptosis, JNK, Autophagy

Cat.No: T6S0232

Synonym: 圣草酚,Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

Kaempferol 3-O-sophoroside

Cat.No: TN1108

Synonym: 槐角黄酮苷,Kaempferol 3-O-beta-sophoroside,山奈酚-3-O-β-D-槐糖苷

Target: Anti-infection

6,7-DIMETHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN

Cat.No: TN6709

Target: Others

Cat.No: T6S1768

Synonym: 水仙苷,Isorhamnetin 3-Rutinoside,Narcissoside

Target: Antioxidant

7,22,25-Stigmastatrienol

Cat.No: TN1327

Target: Others

Soyacerebroside I

Cat.No: TN2223

Synonym: 大豆脑苷 I

Target: IL Receptor, NOS, COX

Melilotigenin C

Cat.No: TN4515

Target: Others

Cat.No: T32551

Cat.No: TN4425

Synonym: Lemannine

Target: Others

8-Prenylkaempferol

Cat.No: TN1347

Synonym: 去甲脱水淫羊藿黄素

Target: p38 MAPK, NF-κB, PI3K

Cat.No: T2S0118

Target: Calcium Channel, 5-HT Receptor, Histamine Receptor

Cat.No: TN5139

Target: Antifection

Cat.No: TN1158

Synonym: Sparteine,(-)-Lupinidine,鹰爪豆碱

Target: Others

Cat.No: TQ0072

Synonym: Scandenolone,攀登鱼藤异黄酮

Target: PKA

Cat.No: TN6686

Dihydrophaseic acid

Cat.No: TMA0132

Target: Others

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