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Search Results for " purine "

586

抑制剂 & 化合物

38

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22013	8-Aminoadenine 7H-purine-6,8-diamine,9H-Purine-6,8-diamine	AChR	Neuroscience
	8-Aminoadenine (7H-purine-6,8-diamine) 是一种Adenine Receptor 的配体，Ki 为0.0341 μM。
T9462	2-Amino-6-cyclopropylamino-9H-purine	Others	Others
	2-Amino-6-cyclopropylamino-9H-purine 是阿巴卡韦(abacavir) 的关键中间体，以氰基乙酸乙酯为原料，经亚硝化、盐酸胍在 EtONa 存在下环合、还原得到2,4,5-三氨基-6-羟基嘧啶
T39856	Purine riboside triphosphate PTP,Purine riboside triphosphate
	Purine riboside triphosphate, a derivative of purine riboside, exhibits structural similarity to adenosine. This naturally occurring base analog possesses inhibitory effects on carcinogenic growth, particularly in cancer ascites cells, by strongly impeding RNA and DNA synthesis.
T60390	PI-55 6-(2-hydroxy-3-methylbenzylamino)purine	Others	Others
	PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1].
T7470	6-Chloropurine 6-氯嘌呤,6-Chloro-9H-purine	Others	Others
	6-Chloropurine (6-Chloro-9H-purine) 是一种制备9-烷基嘌呤和6-巯基嘌呤的中间体，是化学合成的砌块，具有抗肿瘤作用。
T36572	N6-Methyladenine 6-(甲氨基)嘌呤,N6-Methyladenine,6-(Methylamino)Purine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N6-Methyladenine (6-(Methylamino)Purine) 是一种修饰的嘌呤，常见于原核生物、原生生物和植物的基因组中。 N6-Methyladenine 影响多种 DNA 功能，包括复制、修复和表达。
T8445	PU02 PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine	Apoptosis; 5-HT Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) 是5-HT3受体的负变构调节剂，是 6-MP 的一个衍生物。它在 HEK293 细胞测得的转染 5-HT3A 和 5-HT3AB 受体后的 IC50值分别为 0.36 和 0.73 μM。
T76096	Purine nucleoside phosphorylase
	Purine nucleoside phosphorylase 是嘌呤代谢中的关键酶，参与嘌呤挽救途径。Purine nucleoside phosphorylase 缺乏导致 T 细胞功能受损。在无机正磷酸盐作为第二底物的存在下，Purine nucleoside phosphorylase 催化核糖和脱氧核糖核苷的糖苷键断裂，生成嘌呤碱和核糖（脱氧核糖）-1-磷酸。
T21632	Myoseverin	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Myoseverina 是多核肌管可逆分裂成单核片段的诱导剂，影响多种生长因子、免疫调节、细胞外基质重塑和应激反应基因的表达，与伤口愈合和组织再生相关通路的激活一致。
T64944	6-(Methylthio)purine
	6-(Methylthio)purine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64944，CAS号为 50-66-8。
T63737	Purine phosphoribosyltransferase-IN-1
	Purinephosphoribosyltransferase-IN-1 (Compound (S,R)-48) 是一种有效的恶性疟原虫 (Pf)、间日疟原虫 (Pv) 和布氏锥虫 (Tbr) 6-氧嘌呤磷酸核糖基转移酶 (PRT) 抑制剂，他们的 Ki 值分别为 50、20 和 2 nM。
T63738	Purine phosphoribosyltransferase-IN-2
	Purine phosphoribosyltransferase-IN-2 是一种有效的恶性疟原虫 (Pf)，间日疟原虫 (Pv) 以及布氏锥虫 (Tbr) 6-氧嘌呤磷酸核糖基转移酶 (PRT) 抑制剂，他们的Ki 值分别为 30、20 和 2 nM。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T2029	Bohemine	ERK; CDK	Cell Cycle/Checkpoint; MAPK
	Bohemine 是一种合成的选择性CDK 抑制剂，是嘌呤类似物，具有抗癌活性。它对Cdk2/cyclin E、Cdk2/cyclin A 和Cdk9/cyclin T1的IC50分别为 4.6 μM、83 μM 和 2.7 μM。
TNU0907	6-Chloro-9-methyl-9H-purine
	Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Electrophiles
T20038	2-Fluoroadenine NSC-27364,NSC 27364,NSC27364,2-氟腺嘌呤	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2-Fluoroadenine (NSC-27364) 对非增殖性和增殖性肿瘤细胞具有毒性。2-Fluoroadenine 可用于抗癌症的相关研究。
TNU1104	6-Chloro-2-(trifluoromethyl)-9H-purine
	Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleoside bases; Multi-functional; Scaffolds and Templates
TNU0914	6-Benzoylamino-9H-purine-9-acetic acid
	PNA-related Derivatives; PNA monomer
T8380	Bendamustine SDX105,宾达氮芥	Apoptosis; Others; DNA Alkylator/Crosslinker	Apoptosis; DNA Damage/DNA Repair; Others
	Bendamustine (SDX105) 是一种嘌呤类似物，是一种 DNA 交联剂，具有烷基化、抗癌和抗代谢作用。它可激活 DNA 损伤反应和细胞凋亡。
TNU0669	6-Chloro-9-(tetrahydro-2-pyranyl)purine
	Intermediate and building block-electrophile, heterocyclic compound-purine
TNU0483	6-Methyl-9-(beta-D-xylofuranosyl)purine
	Nucleoside Derivatives - Xylo-nucleosides; 6-Modified purine nucleosides
TNU0912	Benzyl 6-amino-9H-purine-9-acetate
	PNA-related Derivatives
TNU1109	2-Methoxy-9-(beta-D-ribofuranosyl)purine
	Nucleoside Derivatives - 6-De-aminopurine nucleosides, 2-Modified purine nucleosides
TNU1211	2-Chloro-9-(beta-D-ribofuranosyl)purine
	Nucleoside Derivatives - Halo-nucleosides, 6-Deaminopurine nucleosides
TNU0095	9-(2-C-methyl-β-D-ribofuranosyl)purine
	2’-C-Methyl nucleoside; 6-De-aminopurine nucleoside
TNU0016	6-(Furan-2-yl)purine-beta-D-riboside
	Nucleoside Derivatives –6-Modified purine nucleosides
TNU0086	Purine -9-beta-D-(2’-deoxy-2’-fluoro) arabinoriboside
	Fluoro-modified nucleoside; 6-De-aminopurine nucleoside; Arabino-nucleoside
TNU0344	6-(1-Piperizinyl)-9-beta-D-ribofuranosyl)-9H-purine
	Nucleoside Derivatives - 6-Modified purine nucleosides
TNU0058	9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)purine
	Nucleosides - fluoro nucleoside, 6-deaminopurine nucleoside
TNU0595	2-Amino-6-O-methyl-2’-O-methyl purine riboside
	Nucleoside Derivatives –6-Modified purine nucleosides, 2’-Modified nucleosides
TNU0596	6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl)purine
	Nucleoside Derivatives –6-Modified purine nucleosides, 2’-Modified nucleosides
TNU0594	6-Ethoxy-9-beta-D-(2-C-methyl-ribofuranosyl)purine
	Nucleoside Derivatives –6-Modified purine nucleosides, 2’-Modified nucleosides
TNU1609	6-Mthoxy-9-beta-D-(2-O-methyl-ribofuranosyl)purine
	Nucleoside Derivatives –6-Modified purine nucleosides, 2’-Modified purine nucleosides
T75073	6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine
	6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。
TNU0343	6-(4-Morpholino)-9-(beta-D-ribofuranosyl)-9H-purine
	Nucleoside Derivatives - 6-Modified purine nucleosides
TNU0101	6-Methyl-9-(2-C-Methyl-beta-D-ribofuranosyl) purine
	2’-C-Methyl nucleoside; 2/6/8- modified nucleoside
T75072	2-Amino-6-O-methyl-2’-O-methyl purine riboside
	2-Amino-6-O-methyl-2’-O-methyl purine riboside 是一种嘌呤核苷类似物，以广泛的抗肿瘤活性及靶向惰性淋巴系统恶性肿瘤为特征。其抗癌机制主要通过抑制 DNA 合成和诱导细胞凋亡（apoptosis）实现。
TNU0770	2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)purine
	Fluoro-modified nucleoside; 6-De-aminopurine nucleoside
TNU1411	2,6-Bis(4-morpholinyl)-9-b-D-ribofuranosyl-9H-purine
	Nucleoside Derivatives –6-Subtituted nucleosides；2-Substituted nucleosides
T64613	2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione
	2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64613。
TNU0491	2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine
	Nucleoside Derivatives - 6-Modified purine nucleosides; Thio-nucleoside
TNU0182	9-(2-Deoxy-β-D-erythropentofuranosyl)-6-methyl-9H-purine
	Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; Prodrug of anticancer agent 6-methylpurine; used for gene therapy
TNU1427	6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
	Nucleoside Derivatives - Other modified nucleosides
T65626	8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione
	8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65626，CAS号为 93703-24-3。
TNU0492	2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine
	Nucleoside Derivatives - 6-Modified purine nucleosides; Thio-nucleoside
TNU0269	6-Methoxy-9-(beta-D-5(R)-methylribofuranosyl)-9H-purine
	Nucleoside Derivatives - 5’-Modified nucleoside; 6-Modified purine nucleoside
TNU0915	2-Amino-6-chloro-9H-purine-9-acetic acid phenyl ester
	Intermediates and Building Blocks - Electrophiles; Scaffolds and Templates
TNU0747	6-Chloro-9-(2’,3’-O-isopropylidene-beta-D-ribofuranosyl)purine
	Halo-nucleoside; intermediate - electrophile
TNU1278	2,6-Dichloro-2',3',5'-triacetyl-purine riboside
	Nucleoside Derivatives - Halo-nucleosides; Scaffolds and Templates
TNU0097	2-Amino-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine
	2’-C-Methyl nucleoside; 6-De-aminopurine nucleoside

化合物

Cat.No: T22013

Synonym: 7H-purine-6,8-diamine,9H-Purine-6,8-diamine

Target: AChR

2-Amino-6-cyclopropylamino-9H-purine

Cat.No: T9462

Target: Others

Purine riboside triphosphate

Cat.No: T39856

Synonym: PTP,Purine riboside triphosphate

Cat.No: T60390

Synonym: 6-(2-hydroxy-3-methylbenzylamino)purine

Target: Others

Cat.No: T7470

Synonym: 6-氯嘌呤,6-Chloro-9H-purine

Target: Others

N6-Methyladenine

Cat.No: T36572

Synonym: 6-(甲氨基)嘌呤,N6-Methyladenine,6-(Methylamino)Purine

Target: Nucleoside Antimetabolite/Analog

Cat.No: T8445

Synonym: PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine

Target: Apoptosis, 5-HT Receptor

Purine nucleoside phosphorylase

Cat.No: T76096

Cat.No: T21632

Target: Others, Microtubule Associated

6-(Methylthio)purine

Cat.No: T64944

Purine phosphoribosyltransferase-IN-1

Cat.No: T63737

Purine phosphoribosyltransferase-IN-2

Cat.No: T63738

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

Cat.No: T2029

Target: ERK, CDK

6-Chloro-9-methyl-9H-purine

Cat.No: TNU0907

2-Fluoroadenine

Cat.No: T20038

Synonym: NSC-27364,NSC 27364,NSC27364,2-氟腺嘌呤

Target: DNA/RNA Synthesis

6-Chloro-2-(trifluoromethyl)-9H-purine

Cat.No: TNU1104

6-Benzoylamino-9H-purine-9-acetic acid

Cat.No: TNU0914

Cat.No: T8380

Synonym: SDX105,宾达氮芥

Target: Apoptosis, Others, DNA Alkylator/Crosslinker

6-Chloro-9-(tetrahydro-2-pyranyl)purine

Cat.No: TNU0669

6-Methyl-9-(beta-D-xylofuranosyl)purine

Cat.No: TNU0483

Benzyl 6-amino-9H-purine-9-acetate

Cat.No: TNU0912

2-Methoxy-9-(beta-D-ribofuranosyl)purine

Cat.No: TNU1109

2-Chloro-9-(beta-D-ribofuranosyl)purine

Cat.No: TNU1211

9-(2-C-methyl-β-D-ribofuranosyl)purine

Cat.No: TNU0095

6-(Furan-2-yl)purine-beta-D-riboside

Cat.No: TNU0016

Purine -9-beta-D-(2’-deoxy-2’-fluoro) arabinoriboside

Cat.No: TNU0086

6-(1-Piperizinyl)-9-beta-D-ribofuranosyl)-9H-purine

Cat.No: TNU0344

9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)purine

Cat.No: TNU0058

2-Amino-6-O-methyl-2’-O-methyl purine riboside

Cat.No: TNU0595

6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl)purine

Cat.No: TNU0596

6-Ethoxy-9-beta-D-(2-C-methyl-ribofuranosyl)purine

Cat.No: TNU0594

6-Mthoxy-9-beta-D-(2-O-methyl-ribofuranosyl)purine

Cat.No: TNU1609

6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine

Cat.No: T75073

6-(4-Morpholino)-9-(beta-D-ribofuranosyl)-9H-purine

Cat.No: TNU0343

6-Methyl-9-(2-C-Methyl-beta-D-ribofuranosyl) purine

Cat.No: TNU0101

2-Amino-6-O-methyl-2’-O-methyl purine riboside

Cat.No: T75072

2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)purine

Cat.No: TNU0770

2,6-Bis(4-morpholinyl)-9-b-D-ribofuranosyl-9H-purine

Cat.No: TNU1411

2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione

Cat.No: T64613

2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine

Cat.No: TNU0491

9-(2-Deoxy-β-D-erythropentofuranosyl)-6-methyl-9H-purine

Cat.No: TNU0182

6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine

Cat.No: TNU1427

8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione

Cat.No: T65626

2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine

Cat.No: TNU0492

6-Methoxy-9-(beta-D-5(R)-methylribofuranosyl)-9H-purine

Cat.No: TNU0269

2-Amino-6-chloro-9H-purine-9-acetic acid phenyl ester

Cat.No: TNU0915

6-Chloro-9-(2’,3’-O-isopropylidene-beta-D-ribofuranosyl)purine

Cat.No: TNU0747

2,6-Dichloro-2',3',5'-triacetyl-purine riboside

Cat.No: TNU1278

2-Amino-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine

Cat.No: TNU0097

Cat. No.	Product Name	Target	Signaling Pathways
T4746	Purine 7H-Imidazo(4,5-d)pyrimidine,嘌呤	Others; Endogenous Metabolite	Metabolism; Others
	Purine (7H-Imidazo(4,5-d)pyrimidine) 是内源性代谢产物的一种。
T7444	6-(Dimethylamino)purine N,N-Dimethyladenine,6-二甲基氨基嘌呤	Serine/threonin kinase; CDK	Cell Cycle/Checkpoint; Metabolism
	6-(Dimethylamino)purine (N,N-Dimethyladenine) 是一种丝氨酸苏氨酸蛋白激酶和 CDK 抑制剂。
T5581	6-(γ,γ-Dimethylallylamino)purine N6-(2-lsopentenyl)adenine,三刺皂荚碱,Triacanthine	Others	Others
	6-(γ,γ-Dimethylallylamino)purine (Triacanthine) 是植物生长调节剂。
TNU0052	Nebularine 9-(beta-D-Ribofuranosyl)-9H-purine	Apoptosis	Apoptosis
	Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine)，是一种嘌呤核苷类似物，具有广谱的抗肿瘤活性，针对惰性淋巴恶性肿瘤并诱导凋亡。Nebularine的抗癌机制依赖于抑制DNA合成。
T0064	Adenine Vitamin B4,腺嘌呤,6-Aminopurine	DNA/RNA Synthesis; Endogenous Metabolite; AChR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Neuroscience
	Adenine (6-Aminopurine) 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T6369	Adenine hemisulfate 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T8186	Xanthosine 5'-monophosphate sodium salt XMP,黄苷-5′-单磷酸钠,L-XMP Sodium	Others	Others
	Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) 是嘌呤代谢的一种中间体。它可用于研究遗传密码，核酸结构以及 DNA，RNA 和蛋白质合成。
T6225	Adenine hydrochloride Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T1004	6-Benzylaminopurine 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine	Others	Others
	6-Benzylaminopurine (6-BAP) 是一种细胞分裂素，能够通过刺激细胞分裂引起植物生长和发育，抑制呼吸激酶，从而延长绿色蔬菜的保鲜。
TQ0273	Neopterin D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤	Endogenous Metabolite	Metabolism
	Neopterin (D-(+)-Neopterin) 是三磷酸腺苷的一种分解产物，是细胞免疫系统激活的标志物。
T19382	Isoguanine 2-羟基-6-氨基嘌呤,异鸟嘌呤	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Isoguanine 是一种嘌呤碱基，是鸟嘌呤的异构体，可作为有机合成的砌块。
T7571	1-Methyladenosine	Endogenous Metabolite	Metabolism
	1-Methyladenosine 是 RNA 修饰，主要来自两种不同的反应类型，酶催化反应以及 RNA 与某些烷化剂反应。
T1362	Hypoxanthine 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin	Others; Endogenous Metabolite	Metabolism; Others
	Hypoxanthine (Purin-6-ol)，也被称为 purine-6-ol 或 Hyp，是一种天然存在的嘌呤衍生物，是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下，Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤，黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。
T2218	8-Azaguanine Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	8-Azaguanine (SK 1150) 是一种具有潜在抗肿瘤活性的嘌呤类似物。它易于掺入核糖核酸中，干扰正常的生物合成途径，从而抑制细胞生长，可作为抗代谢药。
T8075	1,3-Dimethyluric acid	Endogenous Metabolite	Metabolism
	1,3-Dimethyluric acid 是尿路结石中的嘌呤成分之一，是一种人体茶碱代谢的产物。
T2A2537	Guanine 鸟嘌呤;2-氨基次黄嘌呤;2-氨基-6-羟基嘌呤;鸟便嘌呤;鸟粪素;海鸟粪碱;鸟粪环;亚氨基二氧化嘌呤,Pearl essence,Mearlmaid,鸟嘌呤,2-Aminohypoxanthine	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Guanine (2-Aminohypoxanthine) 是一种嘌呤碱基，是核酸中核苷酸的组成部分，由具有共轭双键的稠合嘧啶 - 咪唑环系统组成。
T22218	2'-Deoxyguanosine Deoxyguanosine,Guanine deoxyriboside	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine (Guanine deoxyriboside) 是一种嘌呤核苷，可被2'-dG-II家族的成员识别。2'-Deoxyguanosine 与衰老、突变和致癌有关，可被分子氧氧化。
T1709	2'-Deoxyinosine Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyinosine (Guanine deoxyriboside) 具有抑制人癌细胞株生长的活性，并发现其与嘌呤核苷磷酸化酶缺乏有关。
T5084	Xanthosine dihydrate 黄苷二水合物	Others; Endogenous Metabolite	Metabolism; Others
	Xanthosine dihydrate 是衍生自黄嘌呤和核糖的核苷，能够提高牛和山羊的乳腺干细胞数量和产奶量。
T6523	Guanosine 鸟苷,DL-Guanosine,Vernine,Guanozin	Endogenous Metabolite; HSV	Metabolism; Microbiology/Virology
	Guanosine (DL-Guanosine) 是由鸟嘌呤与核糖环组成的一种核苷，两者之间由 β-N9-配糖键相连，具有抗HSV 的活性。
T0543	7-Methylxanthine Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	7-Methylxanthine (Heteroxanthine) 是一种黄嘌呤的甲基衍生物，是人尿结石的嘌呤成分。
T5073	Inosine 5'-monophosphate disodium salt hydrate Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt) 或肌苷酸是次黄嘌呤的核糖核苷酸，是嘌呤合成过程中形成的第一个核苷酸。
T19792	1,3,7-Trimethyluric acid	Others	Others
	1,3,7-Trimethyluric acid 是咖啡因的代谢产物。其与咖啡因的代谢比可以反映 CYP3A 活性的变化情况。
T2993	Cordycepin 3'-Deoxyadenosine,虫草素	MMP; TNF; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。
T5282	5-Methyluridine Ribothymidine,5-甲基尿甙,Thymine riboside	Others; Endogenous Metabolite	Metabolism; Others
	5-Methyluridine (Thymine riboside) 是发现于人体液中的内源性甲基化核苷。
T0437	Inosine INO 495,NSC 20262,肌苷	ROS; Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Inosine (NSC-20262) 是由腺苷分解代谢产生的一种内源性嘌呤核苷，是腺苷受体A1R 和A2AR 的激动剂，具有抗炎免疫调节，抗伤害和神经保护作用。
T13539	Allopurinol riboside	Others; Endogenous Metabolite; Parasite; Drug Metabolite	Metabolism; Microbiology/Virology; Others
	Allopurinol riboside 是别嘌醇的代谢产物，具有抗寄生虫作用。 Allopurinol riboside 竞争性抑制嘌呤核苷磷酸化酶对肌苷的作用，Ki 为 277 μM。
T2133	Adenosine monophosphate 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate	Endogenous Metabolite; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Adenosine monophosphate (AMP) 是一种嘌呤核糖核苷5'-单磷酸腺苷，是信号转导和调节能量稳态的关键细胞代谢物。它具有EC 3.1.3.11(果糖-二磷酸酶)抑制剂、EC 3.1.3.1(碱性磷酸酶)抑制剂和腺苷A1受体激动剂的作用。
T0626	Uric Acid 尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species; Endogenous Metabolite; Phosphorylase	Immunology/Inflammation; Metabolism; NF-κB
	Uric Acid (Lithic acid) 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ，如单线态氧和过氧亚硝酸盐，抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。
T0665	Xanthine 2,6-Dihydroxypurine,海生丁（黄嘌呤）,黄嘌呤,Isoxanthine	Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Xanthine (Isoxanthine) 是一种植物生物碱，存在于茶、咖啡和可可中。Xanthine 是温和的中枢神经系统激活剂，也是嘌呤降解途径的中间产物。
T4685	INOSINIC ACID Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P	Endogenous Metabolite	Metabolism
	Inosinic acid (IMP) 是内源性代谢产物。
T3S2296	Gardenoside 羟异栀子苷,栀子苷	Others	Others
	Gardenoside 是一种发现于栀子中的天然化合物，具有保肝作用。它对 FFA 诱导的细胞脂肪变性有抑制作用。它可以调节 P2X3 和 P2X7 受体来抑制慢性缩痛。
T4826	L-Histidine monohydrochloride monohydrat	Others; Endogenous Metabolite	Metabolism; Others
	L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一，即蛋白质的组成部分。
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine (Deoxyribose cytidine) 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
T35954	Allantoic acid
	Allantoic acid, a byproduct of uric acid degradation, is implicated in purine metabolism [1][2][3].
T16837	SAICAR	Others	Others
	SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).

天然产物

Cat.No: T4746

Synonym: 7H-Imidazo(4,5-d)pyrimidine,嘌呤

Target: Others, Endogenous Metabolite

6-(Dimethylamino)purine

Cat.No: T7444

Synonym: N,N-Dimethyladenine,6-二甲基氨基嘌呤

Target: Serine/threonin kinase, CDK

6-(γ,γ-Dimethylallylamino)purine

Cat.No: T5581

Synonym: N6-(2-lsopentenyl)adenine,三刺皂荚碱,Triacanthine

Target: Others

Cat.No: TNU0052

Synonym: 9-(beta-D-Ribofuranosyl)-9H-purine

Target: Apoptosis

Cat.No: T0064

Synonym: Vitamin B4,腺嘌呤,6-Aminopurine

Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR

Adenine hemisulfate

Cat.No: T6369

Synonym: 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐

Target: DNA/RNA Synthesis, Endogenous Metabolite

Xanthosine 5'-monophosphate sodium salt

Cat.No: T8186

Synonym: XMP,黄苷-5′-单磷酸钠,L-XMP Sodium

Target: Others

Adenine hydrochloride

Cat.No: T6225

Synonym: Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride

Target: DNA/RNA Synthesis, Endogenous Metabolite

6-Benzylaminopurine

Cat.No: T1004

Synonym: 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine

Target: Others

Cat.No: TQ0273

Synonym: D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤

Target: Endogenous Metabolite

Cat.No: T19382

Synonym: 2-羟基-6-氨基嘌呤,异鸟嘌呤

Target: Nucleoside Antimetabolite/Analog

1-Methyladenosine

Cat.No: T7571

Target: Endogenous Metabolite

Cat.No: T1362

Synonym: 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin

Target: Others, Endogenous Metabolite

Cat.No: T2218

Synonym: Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

1,3-Dimethyluric acid

Cat.No: T8075

Target: Endogenous Metabolite

Cat.No: T2A2537

Synonym: 鸟嘌呤;2-氨基次黄嘌呤;2-氨基-6-羟基嘌呤;鸟便嘌呤;鸟粪素;海鸟粪碱;鸟粪环;亚氨基二氧化嘌呤,Pearl essence,Mearlmaid,鸟嘌呤,2-Aminohypoxanthine

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

2'-Deoxyguanosine

Cat.No: T22218

Synonym: Deoxyguanosine,Guanine deoxyriboside

Target: Endogenous Metabolite

2'-Deoxyinosine

Cat.No: T1709

Synonym: Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷

Target: Others, Endogenous Metabolite

Xanthosine dihydrate

Cat.No: T5084

Synonym: 黄苷二水合物

Target: Others, Endogenous Metabolite

Cat.No: T6523

Synonym: 鸟苷,DL-Guanosine,Vernine,Guanozin

Target: Endogenous Metabolite, HSV

7-Methylxanthine

Cat.No: T0543

Synonym: Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Inosine 5'-monophosphate disodium salt hydrate

Cat.No: T5073

Synonym: Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate

Target: Others, Endogenous Metabolite

1,3,7-Trimethyluric acid

Cat.No: T19792

Target: Others

Cat.No: T2993

Synonym: 3'-Deoxyadenosine,虫草素

Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy

5-Methyluridine

Cat.No: T5282

Synonym: Ribothymidine,5-甲基尿甙,Thymine riboside

Target: Others, Endogenous Metabolite

Cat.No: T0437

Synonym: INO 495,NSC 20262,肌苷

Target: ROS, Endogenous Metabolite, Adenosine Receptor

Allopurinol riboside

Cat.No: T13539

Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite

Adenosine monophosphate

Cat.No: T2133

Synonym: 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate

Target: Endogenous Metabolite, AMPK

Cat.No: T0626

Synonym: 尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

Cat.No: T0665

Synonym: 2,6-Dihydroxypurine,海生丁（黄嘌呤）,黄嘌呤,Isoxanthine

Target: Endogenous Metabolite, Adenosine Receptor

Cat.No: T4685

Synonym: Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P

Target: Endogenous Metabolite

Cat.No: T3S2296

Synonym: 羟异栀子苷,栀子苷

Target: Others

L-Histidine monohydrochloride monohydrat

Cat.No: T4826

Target: Others, Endogenous Metabolite

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

Cat.No: T35954

Cat.No: T16837

Target: Others

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