Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤,核糖和磷酸组成,是信使 RNA 中的一种核苷酸单体。 鸟苷衍生物参与细胞内信号转导,并已鉴定存在于端粒,核糖体 DNA,免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
产品描述 | 5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthylic acid and L-glutamine; which is catalyzed by the enzyme GMP synthase [glutamine-hydrolyzing]. In addition, Guanosine triphosphate and guanosine monophosphate can be biosynthesized from diguanosine tetraphosphate; which is catalyzed by the enzyme bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin action pathway, the telithromycin action pathway, the tobramycin action pathway, and the erythromycin action pathway. Guanosine monophosphate is also involved in several metabolic disorders, some of which include the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria (D and L form) pathway. Outside of the human body, guanosine monophosphate can be found in a number of food items such as onion-family vegetables, millet, chinese water chestnut, and red rice. This makes guanosine monophosphate a potential biomarker for the consumption of these food products. |
别名 | Guanosine 5'-monophosphate disodium salt, 5'-鸟苷酸二钠, 鸟苷钠5'-单磷酸, GMP-5 |
分子量 | 425.2 |
分子式 | C10H14N5Na2O9P |
CAS No. | 5550-12-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mM
DMSO: Insoluble
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 2.3518 mL | 11.7592 mL | 23.5183 mL | 58.7959 mL |
5 mM | 0.4704 mL | 2.3518 mL | 4.7037 mL | 11.7592 mL | |
10 mM | 0.2352 mL | 1.1759 mL | 2.3518 mL | 5.8796 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
5'-Guanylic acid disodium salt 5550-12-9 Metabolism Others Endogenous Metabolite 5'-guanosine monophosphate disodium Inhibitor 5'-Guanylic acid 5'-GMP disodium 1333479 Guanosine 5'-monophosphate disodium salt 5'Guanylic acid disodium salt 5'-鸟苷酸二钠 Guanosine 5'-monophosphate Guanosine 5'-monophosphate disodium GMP5 inhibit 鸟苷钠5'-单磷酸 GMP-5 GMP 5 5' Guanylic acid disodium salt 5'-Guanylic acid disodium inhibitor