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Cat. No. | Product Name | ||
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L5500 | 毒性化合物库 | 262 compounds | |
262 个细胞毒性化合物的特有集合,可用于高通量、高内涵筛选。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15777 |
Loxoribine
RWJ 21757,7-Allyl-8-oxoguanosine,洛索立宾 |
Influenza Virus; TLR | Immunology/Inflammation; Microbiology/Virology |
Loxoribine (RWJ 21757) 是一种鸟苷类似物,是一种口服生物可利用的选择性 Toll 样受体 (TLR) 7 激动剂。 具有抗病毒和抗肿瘤活性。它是一种新型的强效免疫刺激剂,具有较广谱的免疫生物学活性。 | |||
T76691 |
Monalizumab
|
IFNAR; Chk | Cell Cycle/Checkpoint; Immunology/Inflammation |
Monalizumab 是一种新型靶向自然杀伤细胞群 2A (NKG2A) 的免疫检查点抑制剂。Monalizumab 是一种人源化抗 NKG2A 的单克隆抗体,可促使 IFN-γ 产生,从而激活自然杀伤细胞功能。Monalizumab 具有抗肿瘤活性,可用于研究颈部鳞状细胞癌 (HNSCC)。 | |||
T72482 |
Dazostinag disodium
|
STING | Immunology/Inflammation |
Dazostinag disodium (TAK-676) 是一种新型干扰素基因刺激剂 (STING) 激动剂,也是一种免疫系统调节剂,具有抗肿瘤活性,可激活树突状细胞、自然杀伤细胞和 T 细胞。 | |||
T7739 |
L-Leucyl-L-Leucine methyl ester hydrochloride
Leu-Leu-ome hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) 是一种人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物,能够选择性消除具有细胞毒性潜能的淋巴细胞,也能够诱导溶酶体途径应激。 | |||
T77011 |
Flanvotumab
20D7S,IMC 20D7S |
Tyrosinase | Proteases/Proteasome |
Flanvotumab (IMC-20D7S) 是一种人源化针对酪氨酸酶相关蛋白 (TYRP1) 的单克隆抗体。Flanvotumab 具有较强的抗肿瘤活性,通过自然杀伤介导的和抗体依赖的细胞介导的细胞毒作用 (ADCC) 来发挥作用。 | |||
T77423 |
Lirilumab
ONO-4483,IPH2102 |
Virus Protease | Microbiology/Virology |
Lirilumab (IPH2102) 是一种针对杀伤性免疫球蛋白样受体抗体 KIR2D 的抗体,具有抗肿瘤活性,通过 Vav1 依赖性 NF-κB 去抑制增强自然杀伤细胞的抗 HPV+ 宫颈癌活性,可用于研究白血病、头颈部鳞状细胞癌 (SCCHN)。 | |||
T77367 |
Urelumab
BMS-663513,BMS-66513 |
Others | Others |
Urelumab(BMS-66513) 是一种人源化的 IgG4 单克隆抗体,常被当作 CD137 激动剂使用。Urelumab 具有潜在的抗肿瘤活性,可增强 T 细胞和自然杀伤细胞对肿瘤细胞的杀伤作用,并增强 Rituximab 的细胞毒性。Urelumab 可用于研究弥漫性大B细胞淋巴瘤 (DLBCL)合滤泡性淋巴瘤 (FL) 等实体瘤相关疾病。 | |||
T81513 |
Peptide A5K acetate
|
||
Peptide A5K acetate 是 INF7-TAT 衍生物,专用于 CRISPR RNP 传递到 T 细胞。该化合物有效增强 Cas9 RNP 传递到自然杀伤 (NK) 细胞的能力。 | |||
T81669 | NKG2D-IN-2 | ||
NKG2D-IN-2(化合物47)为NKG2D抑制剂,其IC50在NKG2D/MICA及ULBP6 TR-FRET测定中分别为0.1 µM与0.2 µM。 | |||
T81670 | NKG2D-IN-1 | ||
NKG2D-IN-1(compound 21)是一种NKG2D抑制剂,其在NKG2D/MICA和ULBP6 TR-FRET测定中的IC50值分别为0.3 µM和0.7 µM。 | |||
T76315 |
HKPao
|
||
HKPao (Hunter-killer peptide ao) 是一种具有抗肥胖和抗肿瘤促凋亡活性的生物活性肽,能够促使细胞释放囊泡中的细胞色素 c。 | |||
T36858 |
C12 Galactosylceramide (d18:1/12:0)
|
||
C12 Galactosylceramide is a bioactive sphingolipid. It inhibits IL-4 production by 53.84% in EL4 T cells when used at a concentration of 10 μM. C12 Galactosylceramide reduces the growth of human papillomavirus type 16-associated tumors in mice and reduces tumor recurrence following surgical removal or chemotherapy. It also reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus. | |||
T37382 |
1,2,3-Trieicosapentaenoyl-rac-glycerol
|
||
1,2,3-Trieicosapentaenoyl-rac-glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid , which is an ω-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonuclear leukocytes from rabbits and reduces platelet aggregation. It suppresses natural killer cell activity both in vitro and in vivo, in human lymphocytes and murine spleens, respectively, with the in vivo effects lasting up to seven days. | |||
T68755 | NZ-28 | ||
NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis. | |||
T71325 |
ANA-773
|
||
ANA773 is a Toll-like Receptor 7 (TLR7) agonist prodrug with potential immunostimulating activity. Upon oral administration, ANA773 is metabolized into its active form that binds to and activates TLR7, thereby stimulating dendritic cells (DCs) and enhancing natural killer cell (NK) cytotoxicity. This activation results in the production of proinflammatory cytokines, including interferon alpha, and enhanced antibody-dependent cellular cytotoxicity (ADCC). TLR7 is a member of the TLR family, which... | |||
T36323 |
C8 Galactosylceramide (d18:1/8:0)
C8 Galactosylceramide (d18:1/8:0) |
||
C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells when incorporated into the nanoliposomal membrane of nanoliposomal-doxorubicin. C8 Galactosylceramide induces proliferation and cytokine production by splenocytes in vitro at concentrations ranging from 100-1,000 ng/ml but has no effect on natural killer T cell production in vivo.... | |||
T64277 | ODN 1585 | ||
ODN 1585 是一种有效的 IFN 和 TNFα 产生诱导剂,也是一种 NK (natural killer) 的有效刺激剂,可用做疫苗佐剂。ODN 1585 能够增强 CD8+ T 细胞的功能,包括 CD8+ T 细胞介导的 IFN-γ 的产生。ODN 1585 可以诱导小鼠已建立的黑色素瘤消退,对小鼠的疟疾也表现出完全的保护作用。ODN 1585 能够用于研究急性骨髓性白血病 (AML) 和疟疾。 | |||
T77110 | Amivantamab | ||
Amivantamab (JNJ-61186372) 是一种人源 EGFR-MET 双特异性抗体,具有免疫抗癌活性。Amivantamab 可以抑制配体结合,促进受体-抗体复合物的内吞作用和降解,并诱导巨噬细胞的 Fc 依赖性胞吞作用和自然杀伤细胞的抗体依赖性细胞毒性。 | |||
T69944 |
NLG802 HCl
|
||
NLG802 is an orally bioavailable prodrug of indoximod, a methylated tryptophan, with immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, the indoximod prodrug NLG802 is converted to indoximod. Indoximod targets, binds to and inhibits the enzyme indoleamine 2,3-dioxygenase (IDO; IDO1), which converts the essential amino acid tryptophan into the immunosuppressive metabolite kynurenine. By increasing tryptophan levels and decreasing kynurenine levels, indoximod res... | |||
T78218 |
Ilaprazole sodium hydrate
IY-81149 sodium hydrate |
Proton pump | Membrane transporter/Ion channel |
Ilaprazole (IY-81149) sodium hydrate是一种具有口服活性的质子泵抑制剂,可以量依赖性地不可逆抑制H+/K+-ATPase,并在兔壁细胞制剂中展示出IC50为6μM的效力。该化合物主要用于胃溃疡的研究,并已证实是一种有效的T细胞起源蛋白激酶(TOPK)抑制剂。 | |||
T36052 |
Lipoxin A4 methyl ester
LXA4 methyl ester |
||
Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM.[2] LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural... | |||
T74326 | αGalCer-RBD | ||
αGalCer-RBD 是一种佐剂脂蛋白结合物。αGalCer-RBD 可诱导对 SARS-CoV-2及其变异毒株的有效免疫。αGalCer-RBD 结合物诱导 RBD 特异性、产生细胞因子的 T 细胞发育。αGalCer-RBD 有望成为一种有效的 COVID-19 疫苗候选化合物。α-Galactosylceramide (αGalCer) 是一种有效的不变自然杀伤 T 细胞 (iNKT) 激动剂。 | |||
T81917 |
Lorukafusp alfa
hu14.18-IL2,EMD 273063,14.18 mAb |
||
Lorukafusp alfa(14.18 mAb; hu14.18-IL2)是一种由人源化14.18抗GD2抗体和IL210连接而成的免疫细胞因子。该化合物通过其hu14.18-IL2与肿瘤细胞表面的GD2结合,激活抗体依赖性细胞毒性(ADCC)和补体依赖性细胞毒性,以及与效应细胞上Fc受体结合并激活NK和T细胞的活性,从而显现出抗肿瘤效果。 | |||
T37295 |
Ganglioside GM1 Asialo Mixture
|
||
Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive na... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8280 |
Deacetylasperulosidic Acid
去乙酰基车叶草苷酸,去乙酰车叶草苷酸,Desacetyl asperulosidic acid |
IL Receptor; Interleukin | Immunology/Inflammation |
Deacetylasperulosidic Acid 是海巴戟果实的主要植物化学成分。它能够防止体外 4-硝基喹啉1-氧化物诱导的 DNA 损伤,抑制 IL-2的产生以及自然杀伤细胞的活化。它具有抗原活性,抑制仓鼠卵巢细胞和小鼠中染色体畸变的诱导。它可增加超氧化物歧化酶活性,从而具有抗氧化活性。 | |||
T21033 |
Adenanthin
Adenanthin A,Adenanthin-A,AdenanthinA |
||
Adenanthin, a natural inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells. | |||
T82429 | Euphoheliosnoid A | ||
Euphoheliosnoid A (Compound 24) 为二萜类化合物,以 2.5 μM 浓度显著提升 NK 细胞针对 H1299-luci 及 A549-luci 细胞的杀伤效率。 | |||
T82427 | Euphoscopin C | ||
Euphoscopin C, 一种自Euphorbia helioscopia分离得到的二萜类化合物,可显著增强NK细胞对H1299-luci细胞和A549-luci细胞的杀伤活性。 | |||
T36051 |
Lipoxin A4
脂氧素 A4,LXA4 |
||
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide generation in human neutrophils at 0.1 μM.2 LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.[2],[3],[4] Analytical and biological comparisons of synth... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01185 |
DR5/TRAIL R2 Protein, Human, Recombinant (His)
KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis fac... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1. | |||
TMPY-03686 |
NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc)
killer cell lectin-like receptor subfamily C, membe... |
Cynomolgus,Rhesus | HEK293 Cells |
NKG2A/CD159a Protein, Cynomolgus/Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 30.8 kDa and the accession number is Q68VD2. | |||
TMPY-05074 |
NKG2A/CD159a Protein, Human, Recombinant (aa 94-233, His)
CD159A,NKG2A,killer cell lectin-like receptor subfa... |
Human | HEK293 Cells |
NKG2A/CD159a Protein, Human, Recombinant (aa 94-233, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is P26715-1. | |||
TMPY-03376 |
NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)
NKG2-D,NKG2D,KLRK1,killer cell lectin-like receptor... |
Rhesus | Baculovirus Insect Cells |
NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P61252. | |||
TMPY-05414 |
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
D6H12S2489E,NKG2-D,killer cell lectin-like receptor... |
Mouse | Baculovirus Insect Cells |
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2. | |||
TMPY-03256 |
NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)
KLR,killer cell lectin-like receptor subfamily K, m... |
Human | Baculovirus Insect Cells |
NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is P26718-1. | |||
TMPY-00467 |
NKG2D/CD314 Protein, Human, Recombinant (hFc)
D12S2489E,killer cell lectin-like receptor subfamil... |
Human | CHO Cells |
NKG2D/CD314 Protein, Human, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is A0A024RAP8. | |||
TMPY-00217 |
KIR3DL3 Protein, Human, Recombinant (His)
KIR44,KIR3DL7,CD158Z,KIRC1,killer cell immunoglobul... |
Human | HEK293 Cells |
KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-bas... | |||
TMPY-02629 |
KIR2DL1 Protein, Human, Recombinant (His)
NKAT-1,KIR-K64,XXbac-BPG184J6.7,NKAT1,p58.1,killer ... |
Human | HEK293 Cells |
KIR2DL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q6H2H3. | |||
TMPY-03623 |
NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc)
killer cell lectin like receptor F1,KLRF1 |
Cynomolgus | HEK293 Cells |
NKp80, also known as KLRF1, is an activating homodimeric C-type lectin-like receptor that is expressed on nearly all-natural killer cells and stimulates their cytotoxicity and cytokine release. NKp80 stimulates cytotoxicity upon engagement of its genetically linked ligand: myeloid-specific CTLR activation-induced C-type lectin (AICL). NKp80, but not NKp80 mutated at tyrosine 7 (NKp80/Y7F), is tyrosine phosphorylated. Accordingly, NKp80/Y7F, but not NKp80/Y3F or NKp80/Y37F, failed to induce cytot... | |||
TMPY-05477 |
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated
DR5,tumor necrosis factor receptor superfamily, member 10b,T... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is O14763-1. | |||
TMPY-02237 |
KIR2DL3 Protein, Human, Recombinant (His)
NKAT2,MGC129943,KIR-K7c,NKAT2B,CU464054.1,NKAT,KIR-023GB,p58... |
Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.9 kDa and the accession number is Q32WE4. | |||
TMPY-05388 |
DR5/TRAIL R2 Protein, Human, Recombinant (hFc)
tumor necrosis factor receptor superfamily, member 10b,TRAIL... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is AAB67103.1. | |||
TMPY-06835 |
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated
TRICK2A,DR5,tumor necrosis factor receptor superfamily, memb... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.54 kDa and the accession number is NP_003833.4. | |||
TMPK-00277 |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
TRAIL R2,TNFRSF10B,TRICK2,KILLER,DR5,TRAIL receptor... |
Human | HEK293 Cells |
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. | |||
TMPY-00327 |
B7-H6 Protein, Rat, Recombinant (hFc)
B7H6,natural killer cell cytotoxicity receptor 3 li... |
Rat | HEK293 Cells |
B7-H6 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.4 kDa and the accession number is XP_006223356.1. | |||
TMPY-06363 |
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
B7H6,natural killer cell cytotoxicity receptor 3 li... |
Cynomolgus | HEK293 Cells |
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.76 kDa and the accession number is XP_005578557.1. | |||
TMPY-06436 |
CD94 Protein, Human, Recombinant (His)
killer cell lectin-like receptor subfamily D, membe... |
Human | HEK293 Cells |
CD94 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.50 kDa and the accession number is Q13241-1. | |||
TMPJ-00063 |
CD160 Protein, Human, Recombinant (hFc)
CD160 Antigen,CD160,BY55,Natural Killer Cell Recept... |
Human | HEK293 Cells |
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain. It is weakly homologous to KIR2DL4. CD160 is expressed in the spleen, peripheral blood, and small intestine. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD16... | |||
TMPJ-00083 |
NCR3 Protein, Human, Recombinant (hFc)
Activating Natural Killer Receptor p30,CD337,NKp30,... |
Human | HEK293 Cells |
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) matur... | |||
TMPY-06199 |
NKG2A/CD159a Protein, Human, Recombinant (hFc)
NKG2A,NKG2,killer cell lectin-like receptor subfami... |
Human | HEK293 Cells |
NKG2A/CD159a Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is P26715-1. | |||
TMPY-05397 |
NKG2A/CD159a Protein, Human, Recombinant (His), Biotinylated
CD159A,NKG2,NKG2A,killer cell lectin-like receptor ... |
Human | HEK293 Cells |
NKG2A/CD159a Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is P26715-1. | |||
TMPJ-00245 |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
Dr5,CD262,Death receptor 5,Tnfrsf10b,Killer,MK,Tumo... |
Mouse | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 20-40 KDa and the accession number is Q9QZM4. | |||
TMPY-00656 |
2B4/CD244 Protein, Human, Recombinant (hFc)
NKR2B4,2B4,Nmrk,CD244 molecule, natural killer cell... |
Human | HEK293 Cells |
2B4/CD244 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49 kDa and the accession number is Q9BZW8-2. | |||
TMPY-04617 |
B7-H6 Protein, Cynomolgus, Recombinant (hFc)
natural killer cell cytotoxicity receptor 3 ligand ... |
Cynomolgus | HEK293 Cells |
B7-H6 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.2 kDa and the accession number is XP_005578557.1. | |||
TMPY-04495 |
B7-H6 Protein, Rat, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand ... |
Rat | HEK293 Cells |
B7-H6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.1 kDa and the accession number is XP_006223356.1. | |||
TMPY-04618 |
B7-H6 Protein, Cynomolgus, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand ... |
Cynomolgus | HEK293 Cells |
B7-H6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the accession number is XP_005578557.1. | |||
TMPY-06198 |
CD94 Protein, Human, Recombinant (hFc)
killer cell lectin-like receptor subfamily D, membe... |
Human | HEK293 Cells |
CD94 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is Q13241-1. | |||
TMPY-06294 |
2B4/CD244 Protein, Human, Recombinant (His & Avi), Biotinylated
NKR2B4,2B4,Nmrk,CD244 molecule, natural killer cell... |
Human | HEK293 Cells |
2B4/CD244 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.52 kDa and the accession number is Q9BZW8-2. | |||
TMPY-05442 |
KIR2DL3 Protein, Human, Recombinant (hFc)
KIR-K7b,CU464054.1,killer cell immunoglobulin like ... |
Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q32WE4. | |||
TMPK-00276 |
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
ZTNFR9,DR5TRICK2B,DR5,TRAIL receptor 2,TRICKB,TNFRSF10B,TRIC... |
Human | HEK293 Cells |
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. | |||
TMPY-06280 |
2B4/CD244 Protein, Human, Recombinant (hFc & Avi), Biotinylated
NAIL,SLAMF4,NKR2B4,Nmrk,2B4,CD244 molecule, natural kill... |
Human | HEK293 Cells |
2B4/CD244 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 50.80 kDa and the accession number is Q9BZW8-2. | |||
TMPJ-00604 |
KIR2DL4 Protein, Human, Recombinant (His)
CD158 Antigen-Like Family Member D,KIR2DL4,MHC Class I NK Ce... |
Human | HEK293 Cells |
Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of ... | |||
TMPH-03652 |
Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His)
|
UmV6 | P. pastoris (Yeast) |
This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cellular receptors before interaction of the complex with KP6 beta, precipitating cell death. Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.6 kDa and the accession number is P16948. | |||
TMPY-04619 |
B7-H6 Protein, Human, Recombinant (His)
natural killer cell cytotoxicity receptor 3 ligand ... |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85. | |||
TMPY-01437 |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His)
TRAILR2,MK,TRICKB,TRICK2B,TRICK2A,Ly98,DR5,KILLER,t... |
Mouse | HEK293 Cells |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is Q9QZM4. | |||
TMPY-01452 |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)
TRICK2B,DR5,tumor necrosis factor receptor superfamily, memb... |
Mouse | HEK293 Cells |
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4. | |||
TMPY-01568 |
2B4/CD244 Protein, Human, Recombinant (His)
2B4,CD244 molecule, natural killer cell receptor 2B... |
Human | HEK293 Cells |
2B4/CD244 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is Q9BZW8-2. | |||
TMPJ-00246 |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
MK,CD262,Tnfrsf10b,Dr5,Tumor necrosis factor receptor superf... |
Mouse | HEK293 Cells |
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9QZM4. | |||
TMPY-05086 |
KIR2DL5 Protein, Human, Recombinant (hFc)
KIR2DL5.1,CD158F,KIR2DL5.3,killer cell immunoglobul... |
Human | HEK293 Cells |
KIR2DL5A (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A) is a Protein Coding gene. The encoded protein belongs to the immunoglobulin superfamily. The most recently described member of the KIR family, KIR2DL5, is represented in human populations by at least four gene variants, whose exons differ by two to eight nucleotides. KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells... | |||
TMPY-02894 |
NKG2A/CD159a Protein, Human, Recombinant (aa 100-233, His)
NKG2A,CD159A,NKG2,killer cell lectin-like receptor ... |
Human | HEK293 Cells |
NKG2A/CD159a Protein, Human, Recombinant (aa 100-233, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P26715-1. | |||
TMPY-03778 |
NKG2A/CD159a Protein, Mouse, Recombinant (His)
CD159a,NKG2A,killer cell lectin-like receptor subfa... |
Mouse | HEK293 Cells |
NKG2A/CD159a Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is Q9WU31. | |||
TMPY-00377 |
B7-H6 Protein, Human, Recombinant (hFc)
DKFZp686O24166,B7H6,B7-H6,natural killer cell cytot... |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.4 kDa and the accession number is Q68D85. | |||
TMPY-06178 |
B7-H6 Protein, Human, Recombinant (His), Biotinylated
natural killer cell cytotoxicity receptor 3 ligand ... |
Human | HEK293 Cells |
B7-H6 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.1 kDa and the accession number is Q68D85. | |||
TMPJ-01094 |
CD161 Protein, Human, Recombinant (C-hFc)
Killer cell lectin-like receptor subfamily B member... |
Human | HEK293 Cells |
CD161 Protein, Human, Recombinant (C-hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-70 KDa and the accession number is Q12918. | |||
TMPJ-01095 |
CD161 Protein, Human, Recombinant (N-hFc)
Killer cell lectin-like receptor subfamily B member... |
Human | HEK293 Cells |
CD161 Protein, Human, Recombinant (N-hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 55-70 KDa and the accession number is Q12918. | |||
TMPY-06827 |
NKG2D/CD314 Protein, Human, Recombinant (mFc)
killer cell lectin-like receptor subfamily K, membe... |
Human | Baculovirus Insect Cells |
NKG2D/CD314 Protein, Human, Recombinant (mFc) is expressed in Baculovirus insect cells with mFc tag. The predicted molecular weight is 41.83 kDa and the accession number is P26718-1. | |||
TMPJ-00122 |
NKG2D/CD314 Protein, Mouse, Recombinant (His)
KLR,NKG2-D type II integral membrane protein,CD314,NKG2-D-ac... |
Mouse | HEK293 Cells |
NKG2D/CD314 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is O54709. | |||
TMPJ-00097 |
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
member 1,NK cell receptor D,NKG2-D-activating NK receptor, |
Cynomolgus | HEK293 Cells |
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P61252. | |||
TMPY-02381 |
NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc)
Nkrp1f,MGC130066,MGC130065,Nkrp1-f,killer cell lect... |
Mouse | HEK293 Cells |
NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q8VD98. | |||
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