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46

抑制剂 & 化合物

1

天然产物

1742

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T68520	Cl-Necrostatin-1
	Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.
T22672	Cl-4AS-1	Others	Others
	steroidal androgen receptor agonist
T2245	CL-387785 WAY-EKI 785,EKI-785	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	CL-387785 (WAY-EKI 785) 是一种不可逆的EGFR 抑制剂，IC50为 370 pM。
T17477	Azido-PEG1-CH2COO-Cl	Others	Others
	Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker, commonly employed in the synthesis of PROTAC BRD4 Degrader-1[1].
T18637	Boc-C1-PEG2-C4-Cl PROTAC Linker 1	Others	Others
	Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound utilized for the synthesis of PROTACs. This chemical compound serves as a linker in the development of PROTACs[1].
T18626	Dox-Ph-PEG1-Cl PROTAC Linker 34	Others	Others
	Dox-Ph-PEG1-Cl, also referred to as PROTAC Linker 34, is a PEG-based compound employed for the synthesis of PROTACs[1].
T4059	Selamectin UK-124114,司拉克丁,塞拉菌素	Chloride channel; P-gp; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Selamectin (UK-124114) 是半合成的大环内酯，是一种驱虫剂，可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂，可激活神经元和咽肌中的谷氨酸门控氯离子通道，以预防恶丝虫，淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂，IC50为 120 nM。
T20807	Looplure ENT 33266,Pherocon CL,AI3-33266,Cabblemone,(Z)-7-Dodecen-1-olacetate
	Looplure is a chemosterilant, insect attractant and repellent.
T10977	DCEBIO	Potassium Channel	Membrane transporter/Ion channel
	DCEBIO 是1-EBIO 的衍生物，是 T84 结肠细胞中Cl-分泌的极有效的激活剂。DCEBIO 通过激活 hIK1 K+通道和顶端膜的 Cl-传导促进 Cl-的分泌。
T9828	N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide	PAD	Chromatin/Epigenetic
	N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide 是Cl-amidine (S 构型)的消旋形式。Cl-amidine 口服有效的 PAD 抑制剂。
Fr16629	4-(Imidazol-1-yl)phenol
	4-(Imidazol-1-yl)phenol 是一种高效信号增强剂，用于辣根过氧化物酶（HRP）-鲁米诺化学发光（CL）免疫测定。
T13059	T16Ainh-A01	Chloride channel	Membrane transporter/Ion channel
	T16Ainh-A01 是氨基苯基噻唑，是有效的跨膜蛋白 16A 的抑制剂，抑制 TMEM16A 介导的氯离子电流，IC50约为1 µM。TMEM16A (ANO1)起钙激活氯离子通道(CaCC)的作用。
T17996	VH032-PEG5-C6-Cl HaloPROTAC 2	Others	Others
	VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T27037	CL-329167 CL329167,CL 329167
	CL-329167, a angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension.
T17910	(S,R,S)-AHPC-PEG2-C4-Cl E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl	Others	Others
	(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T61155	D-Cl-amidine hydrochloride
	D-Cl-amidine hydrochloride is a potent and highly selective inhibitor of PAD1. It exhibits excellent tolerance and does not induce significant toxicity [1].
T10482L	BB-Cl-Amidine hydrochloride BB-Cl-Amidine hydrochloride (1802637-39-3 free base)	Others	Others
	BB-Cl-Amidine hydrochloride 是一种肽基精氨酸脱胺酶(PAD)的抑制剂。
T18313	Mc-O-Si(di-iso)-Cl	Others	Others
	Mc-O-Si(di-iso)-Cl is a cleavable ADC linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs) like Gemcitabine-O-Si(di-iso)-O-Mc [1].
T60423	Etoxadrol
	Etoxadrol (CL-1848C) 是一个有效且高亲和性的 N-methyl-D-aspartic acid (NMDA) 拮抗剂，可用于麻醉研究。
T78560	U-89843A	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	U-89843A为GABAA受体的变构调节剂，能够增强GABA诱导的Cl-电流。
T17926	(S,R,S)-AHPC-PEG6-C4-Cl VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl	Others	Others
	(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8	Others	Others
	(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T74993	A3AR modulator 1
	A3AR modulator 1 (MRS8054) 是口服活性 A3 腺苷受体 (A3AR(Adenosine Receptor)) 正变构调节剂 (PAM)。该化合物显著增强 Cl-IB-MECA 刺激的 [35S]GTPγS 结合 Emax。
T60701	Fludarabine-Cl
	Fludarabine-Cl 抑制 RNA 腺苷脱氨酶1 (ADAR1) ，它可用于预防和/或治疗与肿瘤或癌症相关的疾病。
T18493	NH2-PEG5-C6-Cl	Others	Others
	NH2-PEG5-C6-Cl (K-7) is a PROTAC linker, which refers to the PEG composition. NH2-PEG5-C6-Cl can be used in the synthesis of a series of PROTACs, and it induces degradation of intracellular molecules by autophagy[1].
T36632	BB-Cl-Yne
	BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-CL-Yne inhibits PAD1-4 with Kinact/KI values of 6,400, 3,600, 10,800, and 4,900 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
T17912	(S,R,S)-AHPC-(C3-PEG)2-C6-Cl VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11	Others	Others
	(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T75820	Gap19 TFA
	Gap19 TFA，源自Cx43胞浆环(CL)的九个氨基酸肽，是高效且选择性的连接蛋白43 (Cx43) 半通道阻滞剂。该肽阻止C末端（CT）与CL之间的分子内相互作用，但不影响GJ通道或Cx40/pannexin-1半通道。此外，Gap19 TFA对心肌有保护作用。
T41179	CL 82198 hydrochloride
	CL 82198 hydrochloride is a selective inhibitor of MMP-13 (89% inhibition at 10μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibitsin vitroinvasion by the human pituitary adenoma cell line HP75. Rescues paclitaxel induced axon degradation and reduces associated neurotoxicity in zebrafish.
T78380	Desacetyl bisacodyl	Others	Others
	Desacetyl bisacodyl为泻药比沙可啶的活性代谢产物，可诱导大鼠结肠及直肠上皮Cl(-)分泌增加，对结肠或直肠产生多种作用，包括促进粘液及氯化物的分泌。
T78003	[D-p-Cl-Phe6,Leu17]-VIP TFA
	[D-p-Cl-Phe6,Leu17]-VIP TFA，为竞争性及选择性血管活性肠肽(VIP)受体拮抗剂，其IC50为125.8 nM。该化合物针对胰高血糖素、促胰液素和GRF受体均不表现活性。
T78599	CK2-IN-9
	CK2-IN-9是一种有效的CK2 kinase选择性抑制剂，IC50值为3 nM。它能降低Wnt报告因子的活性，达到IC50为75 nM。在大鼠体内显示出低暴露量（AUC=0.36 μM/h）及高清除率（CL=65 mL/min/kg）。
T35817	Photoswitchable PAD Inhibitor (technical grade)
	Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without photoactivation, it is a weak inhibitor of PAD2 (IC50 = >100 μM) and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro (kinact/KIs = 2,300, 600, 1,000, and 10,510 M-1min-1 for PAD1-4, respectively) and does not inhibit histone H3 citrullination in HEK29...
T81539	PAT1inh-B01
	PAT1inh-B01为选择性SLC26A6抑制剂，抑制PAT1（Cl-/HCO3-交换器）介导的阴离子交换（IC50: 350 nM），并阻断小肠液体吸收，适用于小肠分泌不足相关疾病研究。
T79730	LB244	STING	Immunology/Inflammation
	LB244为BB-Cl-amidine的同系物，为口服有效的STING抑制剂（EC50=0.8 μM），适用于治疗STING依赖性炎症性疾病。药代动力学研究表明，LB244在小鼠中的口服活性受限。
T36254	dTAGV-1 hydrochloride
	Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-NEG also available. Important: It is recommended that DMSO stock solutions of this compound are made and used on the same day and are not subjected to freeze/thaw.
T79447	IRAK4-IN-25	IRAK	Immunology/Inflammation; NF-κB
	IRAK4-IN-25（化合物38）是口服活性IRAK4抑制剂，具有低清除率（Cl=12 mL/min/kg）和IC50值为7.3 nM。它能抑制促炎细胞因子产生，表现出良好的体外安全性和ADME特性。IRAK4-IN-25主要用于研究炎症和自身免疫性疾病。
T60836	PT4
	PT4 可治疗皮肤利什曼病 (CL) ，它通过降低线粒体膜电位并增加活性氧的产生，从而寄生虫死亡。PT4 对两种利什曼原虫均产生效果，其对L. amazonensis 和L. braziliensis 的 IC50值分别为 125.18 和 233.18 μM。PT4 同时在体内具有有效的抗炎活性。
T26855	BMS-665053 BMS665053
	BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM). In addi
T78110	DOTA-LM3 TFA
	DOTA-LM3 TFA是一種特定結合生長抑素受體(SSTR)的拮抗劑。其結構為p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2。這種複合物常以177Lu-DOTA-LM3 TFA和68Ga-DOTA-LM3 TFA的形式被同位素標記，用於腫瘤的體內示踪。68Ga-DOTA-LM3 TFA展示了優異的生物分布特性、高腫瘤吸收率、良好的腫瘤保留性以及較低的安全風險。而177Lu-DOTA-LM3 TFA則被用於研究DOTATOC陰性的肝轉移，例如胰腺神經內分泌腫瘤(NET)和廣泛的腫瘤血栓形成。
T80155	DOTA-LM3
	DOTA-LM3是一款靶向生长抑素受体(SSTR)的拮抗剂，其结构为p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2。该化合物通常通过同位素标记，如177Lu-DOTA-LM3和68Ga-DOTA-LM3，进行体内肿瘤示踪。68Ga-DOTA-LM3显示出有优异的生物分布特性、高度的肿瘤摄取能力、稳定的肿瘤内保留及较低的安全风险。而177Lu-DOTA-LM3则被用于研究DOTATOC阴性的肝转移案例，针对胰腺NET和广泛性的肿瘤血栓形成治疗具有潜在应用价值。
T36107	YW3-56 YW3-56
	YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4. Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-fold increase in PAD4 inhibition (IC sub>50 about 1-5 μM). At 2-4 μM concentrations, YW3-56 displays mainly cytostatic effects by slowing cell division, whereas at higher concentrations, it exerts cytotoxic effects by altering cell morphology and killing cells[1]. [1]. Wang Y, et ...
T37699	Org 24598
	Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM). Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 in vivo. Chue et al (2013) Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1). Curr.Pharm.Des. 19 1311 PMID:23194655 \|Brown et al (2001) Discovery and SAR of org 24598-a selective glycine uptake inhibi...
T35829	CC-90005
	CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by IL-2 expression[1]. CC-90005 shows the exquisite selectivity of CC-90005, with IC50s for all other family members of >3 μM[1].CC-90005 is a moderate inhibitor of both CYP2C9 (IC50=8 μM) and CYP2C19 (IC50=5.9 μM) in human liver microsomes[1].CC-90005 inhibits IL-2 expression in LRS...
T36745	cDPCP
	cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting proliferation of MDCK cells expressing the human transporters with IC50values of 8.1 and 1.5 μM, respectively. cDPCP inhibits RNA polymerase II-mediated transcription in a reporter assay using HeLa cells. It increases survival in murine S180 sarcoma and P388 leukemia models when ad...
T37851	Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
	Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3, and 5 μM, respectively), as well as NALM-6 cells resistant to daunorubicin and vincristine when used at concentrations ranging...

化合物

Cl-Necrostatin-1

Cat.No: T68520

Cat.No: T22672

Target: Others

Cat.No: T2245

Synonym: WAY-EKI 785,EKI-785

Target: EGFR

Azido-PEG1-CH2COO-Cl

Cat.No: T17477

Target: Others

Boc-C1-PEG2-C4-Cl

Cat.No: T18637

Synonym: PROTAC Linker 1

Target: Others

Cat.No: T18626

Synonym: PROTAC Linker 34

Target: Others

Cat.No: T4059

Synonym: UK-124114,司拉克丁,塞拉菌素

Target: Chloride channel, P-gp, Parasite

Cat.No: T20807

Synonym: ENT 33266,Pherocon CL,AI3-33266,Cabblemone,(Z)-7-Dodecen-1-olacetate

Cat.No: T10977

Target: Potassium Channel

N-[1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide

Cat.No: T9828

Target: PAD

4-(Imidazol-1-yl)phenol

Cat.No: Fr16629

Cat.No: T13059

Target: Chloride channel

VH032-PEG5-C6-Cl

Cat.No: T17996

Synonym: HaloPROTAC 2

Target: Others

Cat.No: T27037

Synonym: CL329167,CL 329167

(S,R,S)-AHPC-PEG2-C4-Cl

Cat.No: T17910

Synonym: E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl

Target: Others

D-Cl-amidine hydrochloride

Cat.No: T61155

BB-Cl-Amidine hydrochloride

Cat.No: T10482L

Synonym: BB-Cl-Amidine hydrochloride (1802637-39-3 free base)

Target: Others

Mc-O-Si(di-iso)-Cl

Cat.No: T18313

Target: Others

Cat.No: T60423

Cat.No: T78560

Target: GABA Receptor

(S,R,S)-AHPC-PEG6-C4-Cl

Cat.No: T17926

Synonym: VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl

Target: Others

(S,R,S)-AHPC-C6-PEG3-C4-Cl

Cat.No: T17911

Synonym: VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8

Target: Others

A3AR modulator 1

Cat.No: T74993

Cat.No: T60701

Cat.No: T18493

Target: Others

Cat.No: T36632

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl

Cat.No: T17912

Synonym: VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11

Target: Others

Cat.No: T75820

CL 82198 hydrochloride

Cat.No: T41179

Desacetyl bisacodyl

Cat.No: T78380

Target: Others

[D-p-Cl-Phe6,Leu17]-VIP TFA

Cat.No: T78003

Cat.No: T78599

Photoswitchable PAD Inhibitor (technical grade)

Cat.No: T35817

Cat.No: T81539

Cat.No: T79730

Target: STING

dTAGV-1 hydrochloride

Cat.No: T36254

Cat.No: T79447

Target: IRAK

Cat.No: T60836

Cat.No: T26855

Synonym: BMS665053

Cat.No: T78110

Cat.No: T80155

Cat.No: T36107

Synonym: YW3-56

Cat.No: T37699

Cat.No: T35829

Cat.No: T36745

Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)

Cat.No: T37851

Cat. No.	Product Name	Target	Signaling Pathways
TN5033	Skullcapflavone I	IL Receptor; Caspase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se

天然产物

Skullcapflavone I

Cat.No: TN5033

Target: IL Receptor, Caspase, Prostaglandin Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01884	MMP-8 Protein, Human, Recombinant CLG1,HNC,PMNL-CL,matrix metallope...	Human	HEK293
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a memb...
TMPJ-01303	Collectin-11 Protein, Human, Recombinant (His) Collectin-11,COLEC11,	Human	Human Cells
	Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compa...
TMPK-01286	MMP-8 Protein, Cynomolgus, Recombinant (His) Collagenase 2,HNC,CLG1,MMP8,PMNL-CL	Cynomolgus	HEK293
	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was signifi...
TMPY-04404	DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST) doublecortin-like kinase 1,CL1,DC...	Human	Baculovirus-Insect Cells
	DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCA...
TMPY-04752	DCLK1 Protein, Human, Recombinant doublecortin-like kinase 1,CL1,D<...	Human	Baculovirus-Insect Cells
	DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCA...
TMPY-01377	MMP-8 Protein, Human, Recombinant (His) MMP-8,HNC,matrix metallopeptidase 8,CLG1,P...	Human	HEK293
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a memb...
TMPK-00461	KIR2DL1 Protein, Human, Recombinant (His & Avi) CD158A,CD158Ankat1,p58.1...	Human	HEK293
	KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
TMPK-00462	KIR2DL1 Protein, Human, Recombinant (His & Avi), Biotinylated CD158Ankat1,KIR221,KIR2DL1	Human	HEK293
	KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
TMPY-02001	RTN4 Protein, Human, Recombinant (GST) UNG1,NOGO,reticulon 4,RTN4-A,Nbla00271,NOG...	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that contains one reticulon domain. Isoform 1 of RTN4 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 of RTN4 is widely expressed except for the liver. Isoform 3 of RTN4 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 ...
TMPJ-01055	HBA1 Protein, Human, Recombinant (His) α-globin,Hemoglobin subunit alpha,HBH,HBA-T3,Alpha-globin,He...	Human	E. coli
	Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2, H+, Cl−, and 2,3-DPG (2,3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans, which mediates the transport...
TMPY-03414	ABHD10 Protein, Human, Recombinant (aa 53-306, His) ABHD10,abhydrolase domain containing 10	Human	Baculovirus-Insect Cells
	Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG). It is known that AcMPAG, which may be an immunotoxic metabolite, is deglucuronidated in human liver. AcMPAG deglucuronidation activity was detected in both human liver cytosol (HLC) and microsomes (HLM). By purification from HLC with column chromatographic purification steps, the en...
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Angiopoietin-2,AGPT2,angiopoietin 2,ANG2	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization. ANG-2 mod...
TMPY-01298	CADM1 Protein, Human, Recombinant (His) Necl-2,cell adhesion molecule 1,SYNCAM,BL2...	Human	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular domain of IGSF4 and mediate homophilic or heterophilic interactions independently of Ca2+. The cytoplasmic domain of IGSF4 contains the binding motifs that connect to actin fibers. Since IGSF4 has been characterized by several independent research groups, this molecule is called...
TMPY-04779	BTN3A2 Protein, Human, Recombinant (His) BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...	Human	HEK293
	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted...
TMPY-03363	C-Reactive Protein Protein, Human, Recombinant C-Reactive Protein,C-reactive protein, pentraxin-related,PTX...	Human	HEK293
	C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monit...
TMPY-02512	Alpha-Synuclein Protein, Human, Recombinant PD1,α-Synuclein,PARK4,synuclein, ...	Human	E. coli
	Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the...
TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD28 molecule,Tp44	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc) 1810061I13Rik,Cl	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and...
TMPY-04824	CTLA-4 Protein, Human, Recombinant CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD4,cytotoxic T...	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role i...
TMPY-00986	IL-34 Protein, Mouse, Recombinant (His) interleukin 34,2010004A03Rik,AI593503	Mouse	HEK293
	IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colon...
TMPY-03273	IL-18 Protein, Mouse, Recombinant interleukin 18,白细胞介素,白介素,Il-18,Igif	Mouse	E. coli
	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi...
TMPY-02412	ENO1 Protein, Human, Recombinant (His) PPH,NNE,enolase 1, (alpha),ENO1L1...	Human	E. coli
	The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make ...
TMPY-01834	CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) CD16,Fc receptor, IgG, low affinity III	Mouse	HEK293
	Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as...
TMPY-01912	Cadherin 17/CDH17 Protein, Human, Recombinant (His) HPT-1,cadherin 17, LI cadherin (liver-inte...	Human	HEK293
	Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-01055	IL-4R Protein, Human, Recombinant (His) interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-01608	Decorin Protein, Human, Recombinant (His) PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role...
TMPY-04810	CD47 Protein, Mouse, Recombinant (His) AA407862,CD47 molecule,AW108519,91	Mouse	HEK293
	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-01280	FOLR2 Protein, Human, Recombinant (His) FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...	Human	HEK293
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPY-00843	IL-25/IL17E Protein, Human, Recombinant (hFc) interleukin 25,IL17E	Human	HEK293
	Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–produ...
TMPY-01462	IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) interleukin 11 receptor subunit alpha,hCG_...	Human	HEK293
	Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increas...
TMPY-05277	IL-4R Protein, Human, Recombinant (hFc) IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-03256	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) KLR,killer cell lectin-like receptor subfamily K, member	Human	Baculovirus-Insect Cells
	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim...
TMPY-05579	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated PRR1,ED4,PVRR,nectin-1,OFC7,SK-12...	Human	HEK293
	Poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin-1; CD111), also known as PVRL1 is a cell adhesion molecule belonging to the immunoglobulin superfamily that can bind to virion glycoprotein D (gD) to mediate entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV). CD111/Nectin-1/PVRL1 colocalizes with E-cadherin at adherens junctions in epithelial cells. The disruption of cell junctions can result in the redistribution of nectin-1. To determine whether disruption of ...
TMPY-00939	Thrombopoietin Protein, Mouse, Recombinant (His) thrombopoietin,Mpllg,Tpo,Mgdf,Ml	Mouse	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) angiopoietin 1,AGPT,AGP1,ANG1	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures...
TMPY-03762	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) cadherin 1, type 1, E-cadherin (epithelial...	Human	HEK293
	Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is a calcium-dependent cell adhesion molecule the intact function of which is crucial for the establishment and maintenance of epithelial tissue polarity and structural integrity. Mutations in CDH1 occur in diffuse type gastric cancer, lo...
TMPY-01431	L1CAM Protein, Human, Recombinant (His) N-CAM-L1,MASA,HSAS,L1 cell adhesion molecu...	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif ...
TMPY-01701	IL-12RB1 Protein, Human, Recombinant (His) interleukin 12 receptor, β1,IL12R...	Human	HEK293
	Interleukin 12 receptor, beta 1 is also known as IL-12 receptor beta component, IL-12R subunit beta-1, and CD212 antigen (CD212). IL12RB1(CD212) is a subunit of the interleukin 12 receptor. IL12RB1(CD212) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukin 12 (IL12) with a low affinity and is thought to be a part of the IL12 receptor complex. IL12RB1(CD212) forms a disulfide-linked oligomer, which is required for its IL12 bind...
TMPY-01907	VSIG4 Protein, Human, Recombinant (His) Z39IG,CRIg,V-set and immunoglobulin domain containing 4	Human	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPY-02115	R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) CRISTIN1,THSD2,R-spondin 3,PWTSR	Human	HEK293
	R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s...
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His) NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NF...	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T...
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like...	Human	HEK293
	LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophag...
TMPY-02105	SCF Protein, Mouse, Recombinant (His) Gb,Kitlg,SF,Clo,Mgf,SLF,Sl,KIT ligand,SCF,Con	Mouse	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in ...
TMPY-00828	Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His) MPS2,IDS,SIDS,iduronate 2-sulfatase	Human	HEK293
	Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an...
TMPY-00991	LIFR Protein, Human, Recombinant (His) STWS,CD118,SJS2,LIF-R,leukemia inhibitory ...	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus affects the differentiation, proliferation, and survival of a wide variety of cells in the adult and the embryo. Besides LIF, LIFR can also bind to and activate CNTF (ciliary neurotrophic factor) and CLC (Cardiotrophin Like Cytokine). Evidence showed that in the retina, LIFR activat...
TMPY-03630	MZB1/PERP1 Protein, Human, Recombinant (His) MEDA-7,marginal zone B and B1 cell-specific protein...	Human	HEK293
	MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expressi...
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) CD22 molecule,SIGLEC-2,SIGLEC2	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. In addition to its potential role as a mediator of intercellular interactions, signal transduction through CD22 can activate B cells and modulate antigen receptor signaling in vitro. ...
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重组蛋白

MMP-8 Protein, Human, Recombinant

Cat.No: TMPY-01884

Species: Human

Expression System: HEK293

Collectin-11 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01303

Species: Human

Expression System: Human Cells

MMP-8 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01286

Species: Cynomolgus

Expression System: HEK293

DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST)

Cat.No: TMPY-04404

Species: Human

Expression System: Baculovirus-Insect Cells

DCLK1 Protein, Human, Recombinant

Cat.No: TMPY-04752

Species: Human

Expression System: Baculovirus-Insect Cells

MMP-8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01377

Species: Human

Expression System: HEK293

KIR2DL1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00461

Species: Human

Expression System: HEK293

KIR2DL1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00462

Species: Human

Expression System: HEK293

RTN4 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02001

Species: Human

Expression System: E. coli

HBA1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01055

Species: Human

Expression System: E. coli

ABHD10 Protein, Human, Recombinant (aa 53-306, His)

Cat.No: TMPY-03414

Species: Human

Expression System: Baculovirus-Insect Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03745

Species: Human

Expression System: HEK293

ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00664

Species: Human

Expression System: HEK293

CADM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01298

Species: Human

Expression System: HEK293

BTN3A2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04779

Species: Human

Expression System: HEK293

C-Reactive Protein Protein, Human, Recombinant

Cat.No: TMPY-03363

Species: Human

Expression System: HEK293

Alpha-Synuclein Protein, Human, Recombinant

Cat.No: TMPY-02512

Species: Human

Expression System: E. coli

CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-05354

Species: Human

Expression System: HEK293

CLEC-2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00586

Species: Mouse

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant

Cat.No: TMPY-04824

Species: Human

Expression System: HEK293

IL-34 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00986

Species: Mouse

Expression System: HEK293

IL-18 Protein, Mouse, Recombinant

Cat.No: TMPY-03273

Species: Mouse

Expression System: E. coli

ENO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02412

Species: Human

Expression System: E. coli

CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)

Cat.No: TMPY-01834

Species: Mouse

Expression System: HEK293

Cadherin 17/CDH17 Protein, Human, Recombinant (His)

Cat.No: TMPY-01912

Species: Human

Expression System: HEK293

IL-4R Protein, Human, Recombinant (His)

Cat.No: TMPY-01055

Species: Human

Expression System: HEK293

Decorin Protein, Human, Recombinant (His)

Cat.No: TMPY-01608

Species: Human

Expression System: HEK293

CD47 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04810

Species: Mouse

Expression System: HEK293

FOLR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01280

Species: Human

Expression System: HEK293

IL-25/IL17E Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00843

Species: Human

Expression System: HEK293

IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)

Cat.No: TMPY-01462

Species: Human

Expression System: HEK293

IL-4R Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05277

Species: Human

Expression System: HEK293

NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)

Cat.No: TMPY-03256

Species: Human

Expression System: Baculovirus-Insect Cells

PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05579

Species: Human

Expression System: HEK293

Thrombopoietin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00939

Species: Mouse

Expression System: HEK293

ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05435

Species: Human

Expression System: HEK293

E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03762

Species: Human

Expression System: HEK293

L1CAM Protein, Human, Recombinant (His)

Cat.No: TMPY-01431

Species: Human

Expression System: HEK293

IL-12RB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01701

Species: Human

Expression System: HEK293

VSIG4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01907

Species: Human

Expression System: HEK293

R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

Cat.No: TMPY-02115

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-04793

Species: Human

Expression System: HEK293

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06076

Species: Human

Expression System: HEK293

SCF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02105

Species: Mouse

Expression System: Baculovirus-Insect Cells

Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)

Cat.No: TMPY-00828

Species: Human

Expression System: HEK293

LIFR Protein, Human, Recombinant (His)

Cat.No: TMPY-00991

Species: Human

Expression System: HEK293

MZB1/PERP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03630

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)

Cat.No: TMPY-05566

Species: Human

Expression System: HEK293

--------- 更多 ---------

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