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Cat. No. | Product Name | ||
---|---|---|---|
L4600 | 植物来源化合物库 | 3048 compounds | |
3048 个植物来源天然产物的独特集合,来自277类植物的精心之选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13538 |
AlbA-DCA
|
ROS | Immunology/Inflammation |
AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid subunit. It can induce a marked increase in intracellular ROS and alleviate the accumulation of lactic acid in the tumor microenvironment, and also selectively | |||
T20600 |
Kaolin
Clay 347,Hydrated aluminum silicate,Bolus alba,HSDB 630,Altowhite,China clay,高岭土 |
Others | Others |
Kaolin (Bolus alba) 是一种以高岭石族矿物为主的粘土。 Kaolin 提高了这种监测血友病治疗方法的敏感性。 | |||
T21358 |
Dalbavancin
BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl,达巴万星 |
Antibacterial; Antibiotic | Microbiology/Virology |
Dalbavancin (BI-397) HCl 是一种半合成的脂糖肽抗生素,对革兰氏阳性细菌有杀菌活性。Dalbavancin 抑制金黄色葡萄球菌和炭疽芽孢杆菌的 MIC90分别为 0.06 μg/mL 和 0.25 μg/mL。 | |||
T7725 |
Albaconazole
W 0027,UR-9825,UR9825,W-0027 |
P450; Antifungal | Metabolism; Microbiology/Virology |
Albaconazole (W-0027)是一种小分子真菌细胞色素P450家族成员51 (fungal CYP51A1)抑制剂。它可用于治疗真菌感染、皮肤和肌肉骨骼疾病,可用于研究外阴阴道念珠菌病、Chagas病和泌尿生殖系统疾病。 | |||
T75253 | Dalbavancin hydrochloride | ||
Dalbavancin hydrochloride (MDL-63397 hydrochloride)为半合成脂糖肽类抗生素,有效对抗革兰氏阳性菌。其对金黄色葡萄球菌与炭疽芽孢杆菌的MIC90分别为0.06 μg/mL与0.25 μg/mL。 | |||
T125711 |
Eclalbasaponin IV
|
||
Eclalbasaponin IV 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125711,CAS号为 158511-61-6。 | |||
T29830 |
Albacarcin V
NSC354844,NSC-354844,NSC 354844 |
||
Albacarcin V is a biochemical. | |||
T125712 |
Eclalbasaponin III
|
||
Eclalbasaponin III 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125712,CAS号为 158511-60-5。 | |||
T124310 |
Albanin A
|
||
Albanin A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124310。 | |||
T81970 |
Kuwanon T
|
||
Kuwanon T为一种源自桑树根皮的异戊二烯黄酮类化合物,能抵御t-BHP诱导的氧化应激,其EC50值为30.32 μM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3384 |
Wedelolactone
蟛蜞菊内酯,IKK Inhibitor II |
Apoptosis; NF-κB; Lipoxygenase; Caspase | Apoptosis; Metabolism; NF-κB; Proteases/Proteasome |
Wedelolactone (IKK Inhibitor II) 是来自旱莲草的一种天然产物,通过阻断 IκBα 的磷酸化和降解来抑制细胞中 NF-κB 介导的基因转录,具有抗癌,抗炎和抗氧化活性。 | |||
TN7121 |
d-Epigalbacin
(-)-Zuonin A,表加巴辛 |
JNK | MAPK |
d-Epigalbacin ((-)-Zuonin A) 是一种天然木质素。d-Epigalbacin 是一种强效、选择性的JNKs 抑制剂,JNK1、JNK2和JNK3的IC50s 分别为1.7μM、2.9μM 和1.74μM。 | |||
TN1600 |
Eclalbasaponin I
|
Others | Others |
Eclalbasaponin I 分离自鳢肠中,具有抗肿瘤作用,能够抑制肝癌细胞 smmc-7721 的增殖(IC50:111.1703 μg/ml)。 | |||
TN3371 | Albatrelin G | Others | Others |
Albatrelin G shows weak cytotoxic activity to cell lines HL-60, SMMC-7721, A-549, and MCF-7, in vitro. | |||
T75602 | Albanol B | ||
Albanol B 是一种芳基苯并呋喃衍生物,可从桑葚中分离得到。Albanol B 具有抗阿尔茨海默病、抗菌和抗氧化活性。Albanol B 抑制癌细胞增殖,下调 CDK1表达。Albanol B 还会诱导细胞周期停滞在 G2/M 期,诱导细胞凋亡 (apoptosis)。Albanol B 诱导线粒体 ROS 产生并增加 AKT 和 ERK1/2的磷酸化水平。 | |||
T2S1115 |
Albaspidin AA
|
Antifection | Microbiology/Virology |
Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal activity against L4 stage larvae. | |||
T29831 |
Albaspidin
|
||
Albaspidin is a biochemical. | |||
TN3370 |
Albatrelin C
|
Others | Others |
Albatrelin C is a natural product from Albatrellus ovinus. | |||
TN3369 |
Albatrelin A
|
Others | Others |
Albatrelin A is a natural product from Albatrellus ovinus. | |||
TN1365 |
Albaspidin AP
|
Fatty Acid Synthase | Metabolism |
Albaspidin-AP, -PP, -PB inhibit Fatty acid synthase (FAS) with IC50 values ranging from 23.1+/-1.4 to 71.7+/-3.9 microM, they could be considered to be a promising class of FAS inhibitors, and FAS is emerging as a potential therapeutic target to treat can | |||
T13706 |
Glucosinalbate
|
Others | Others |
Glucosinalbate 是一种天然产物,分离自拟南芥。 | |||
TN2212 |
Glucosinalbate potassium
白芥子钾盐,Sinalbin potassium salt |
Others | Others |
Sinalbin potassium salt is a natural product | |||
TQ0301 |
Kuwanon A
|
NO Synthase | Immunology/Inflammation |
Kuwanon A 抑制一氧化氮的产生 (IC50: 10.5 μM)。Kuwanon A 是从桑树 (Morus alba L.) 中分离出来的黄酮衍生物。 | |||
TN1261 |
3-O-Caffeoylquinic acid methyl ester
|
Others | Others |
3-O-Caffeoylquinic acid methyl ester 是 Pyrrosia calvata 的成分之一。 | |||
TN7027 |
Benzoylalbiflorin
Paeonivayin,苯甲酰芍药内酯苷 |
Others | Others |
Benzoylalbiflorin (Paeonivayin) 是一种分离自 Radix Paeoniae Alba 的单萜。其中 Radix Paeoniae Alba 是传统中药,已用于研究类风湿关节炎,能够缓解炎症,闭经,鼻出血,腹痛和其他症状。 | |||
TN1949 |
Moracin C
桑辛素 C,5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇 |
ROS; NO Synthase | Immunology/Inflammation |
Moracin C 是一种发现于Morus mesozygia、Morus alba var. multicaulis 中的天然化合物,是一种抗炎剂。Moracin C 可抑制细胞中的一氧化氮(NO)释放和LPS 激活的活性氧(ROS)。 | |||
T5742 |
Isodemethylwedelolactone
异去甲蟛蜞菊内酯,Isodemethylwedelolacton |
Others | Others |
Isodemethylwedelolactone (Isodemethylwedelolacton) 是一种促凝剂,也是溶血性成分,分离自 Eclipta alba。 | |||
T5S0689 |
Demethylwedelolactone
去甲蟛蜞菊内酯,去甲基蟛蜞内酯 |
Serine Protease | Proteases/Proteasome |
Demethylwedelolactone 是一种分离自 Eclipta alba 中的 coumestan 天然产物。它能抑制乳腺癌细胞的移动和侵袭,是一种有效的trypsin 抑制剂(IC50:3.0 μM)。 | |||
T3773 |
Oxypaeoniflorin
氧化芍药苷,Oxypaeoniflora |
Others | Others |
Oxypaeoniflorin (Oxypaeoniflora) 从 Paeoniae 中分离得到的单萜糖苷化合物,是一种抗氧化剂,是具有神经保护和抗炎作用。 | |||
TN1252 |
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone
|
Apoptosis | Apoptosis |
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone 是一种来自桑叶的黄酮类化合物,具有细胞毒性,可诱导细胞凋亡。 | |||
T2830 |
Betulinic acid
白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid |
Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy | Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物,是真核细胞拓扑异构酶 I 的抑制剂,IC50值为 5 μM,具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。 | |||
TN1956 |
Mulberrofuran G
|
Phosphatase; HBV; Glucosidase | Metabolism; Microbiology/Virology |
Mulberrofuran G分离自自 Morus alba L.,具有抗乙型肝炎病毒活性,可保护缺血损伤诱导的细胞死亡。Mulberrofuran G 是一种 PTP1B 和 α-葡萄糖苷酶的双重抑制剂,可用于研究阿尔茨海默症。 | |||
TN1950 |
Moracin M
|
PDE | Metabolism |
Moracin M 是桑白皮中的一种酚类成分,有效的磷酸二酯酶 4 (PDE4) 抑制剂,对于 PDE4D2,PDE4B2,PDE5A1 和 PDE9A2 的 IC50 分别为 2.9 μM,4.5 μM,> 40 μM 和 > 100 μM。Moracin M 具有抗炎活性。 | |||
T82054 |
Ipalbine
|
||
Ipalbine为源自Ipomoea alba L的六氢吲哚生物碱类化合物。 | |||
T81742 |
Mulberrofuran B
|
||
Mulberrofuran B,一种从Morus alba乙醇提取物中分离得到的化合物,展现了抗氧化活性。 | |||
T38524 |
Paeoniflorin sulfite
|
||
During the sulfur-fumigation process of Paeoniae Radix Alba, Paeoniflorin, which serves as a principal constituent, can be converted into Paeoniflorin sulfite. | |||
TN2814 |
23-Hydroxybetulin
|
Others | Others |
23-Hydroxybetulin is a natural product from Betula alba L. | |||
TN4401 |
Kuwanol C
|
Others | Others |
Kuwanol C 是一种天然产物,存在于Morus alba L。 | |||
TN2453 |
Kuwanol A
|
Others | Others |
Kuwanol A is a natural product from Morus alba L. | |||
T83479 |
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione
|
||
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione 是一种从丹参酮 (Salvia miltiorrhiza f. alba) 中提取的化学物质,具有二氢异丹参酮结构,显示出细胞毒性和抗肿瘤的活性。 | |||
TN1953 |
Morusinol
桑根皮醇,桑树醇 |
ERK; MEK; Autophagy; Ras | Autophagy; GPCR/G Protein; MAPK |
Morusinol 是从桑树根皮中提取出的类黄酮。 Morusinol 具有抗血小板和抗癌活性,在体内抑制动脉血栓形成,通过诱导自噬、G2/M 细胞周期阻滞、抑制细胞侵袭和迁移以及靶向 Ras/MEK/ERK 通路发挥抗肿瘤活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03193 |
Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO)
DNA/RNA-binding protein Alba |
Pyrococcus furiosus | E. coli |
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes. Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molec... | |||
TMPY-03962 |
AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF |
Human | HEK293 Cells |
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... | |||
TMPH-03197 |
Que a 1 Protein, Quercus alba, Recombinant (B2M & His)
|
Quercus alba | E. coli |
N/A. Que a 1 Protein, Quercus alba, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 19.4 kDa and the accession number is P85126. | |||
TMPY-04523 |
Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is A4U7A6.1. | |||
TMPY-04886 |
Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/Albany/12/1951) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is A4U7A6. | |||
TMPY-05006 |
Alpha Lactalbumin/LALBA Protein, Human, Recombinant (His)
α Lactalbumin/LALBA,LYZL7,lactalbumin alpha,lactalb... |
Human | HEK293 Cells |
Alpha Lactalbumin/LALBA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is A0A080YV01. | |||
TMPY-00187 |
Alpha Lactalbumin/LALBA Protein, Human, Recombinant (mFc)
LYZL7,lactalbumin α,lactalbumin alpha,α Lactalbumin/LALB... |
Human | HEK293 Cells |
Alpha Lactalbumin/LALBA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.5 kDa and the accession number is A0A080YV01. | |||
TMPY-05938 |
Influenza A H3N2 (A/Albany/18/1968) Neuraminidase/NA Protein (His)
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Albany/18/1968) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is A4JZ31. |