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Search Results for " 藜芦醇 "

9

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T3330L	cis-trismethoxy Resveratrol (Z)-3,5,4'-Trimethoxystilbene,顺式白藜芦醇三甲醚	Microtubule Associated	Cytoskeletal Signaling
	cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) 抑制微管蛋白聚合 (IC50 = 4 μM) 并具有抗有丝分裂作用。
T5541	PDM11 1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth,PDM 11	AhR	Immunology/Inflammation; Metabolism
	PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) 是抗氧化剂白藜芦醇的衍生物。它在白藜芦醇活性测定中不活跃。它对辐射分解产生的羟基自由基引发的亚油酸胶束氧化没有明显的保护作用。
T7827	Glycyrrhizinic acid, potassium salt	Others	Others
	Glycyrrhizinic acid, potassium salt 可减轻藜芦醇引起的室性心律失常。
T3585	TMS (E)-2,3',4,5'-tetramethoxystilbene,2,3',4,5'-Tetramethoxystilbene	P450	Metabolism
	TMS (2,3',4,5'-Tetramethoxystilbene) 是一种白藜芦醇的甲基化衍生物，也是具有选择性的CYP1B1竞争性抑制剂，其IC50=6 nM，Ki=3 nM。它对 CYP1A1 (IC50:300 nM) 及 CYP1A2 (IC50:3.1 μM) 的抑制作用较小。它具有抗癌作用。
T36674	DMU-212	Apoptosis; ERK	Apoptosis; MAPK
	DMU-212 是具有口服活性的白藜芦醇的甲基化衍生物，表现出抗分裂、抗增殖、抗氧化和促进细胞凋亡的活性。它通过诱导凋亡和激活ERK1/2蛋白阻止有丝分裂。
T12781	RV01	Others	Others
	RV01 是一种新型的白藜芦醇喹啉取代类似物，可抑制 DNA 损伤，降低乙醇诱导的乙醛脱氢酶 (ALDH2) 的 mRNA 表达，具有清除羟自由基的活性。RV01 降低 iNOS 的表达，具有抗神经炎症作用。RV01降低肿瘤坏死因子-a (TNF-a)和白细胞介素-6 (IL-6) mRNA 水平和分泌，抑制lps 诱导的ROS 生成和烟酰胺腺嘌呤二核苷酸磷酸(NADPH)氧化酶活化，降低toll 样受体4 (TLR4)的蛋白表达，抑制lps 诱导的丝裂原活化蛋白激酶(MAPK)和核转录因子-кB (NF-кB)信号通路的激活。
T36518	Resveratrol-4'-O-D-Glucuronide
	Resveratrol-4'-O-D-Glucuronide 具有抗脂肪堆积的特性，可由白藜芦醇代谢，可用于代谢相关研究。
T74841	NF-κB-IN-9
	NF-κB-IN-9 是一种靶向核因子 NF-κB 的声敏剂 (λex/λem=489/628 nm)。NF-κB-IN-9 由于分子中有两个白藜芦醇单元，而对 NF-κB 信号表现出强烈的抑制作用。NF-κB-IN-9 具有抗肿瘤活性，并对癌细胞表现出显着的声细胞毒性。NF-κB-IN-9 在小鼠移植模型中具有生物安全性。
T60395	Nrf2-ARE/hMAO-B/QR2 modulator 1
	Nrf2-ARE/hMAO-B/QR2 modulator 1是一种新的基于白藜芦醇的多靶点定向配体(MTDL)，显示出良好的平衡 MTDL 特征:细胞激活 Nrf2-ARE 通路(CD = 9.83 μM)，选择性抑制 hMAO-B 和 QR2 (IC50s = 8.05和0.57 μM)，并具有较佳的促进海马神经发生的能力。Nrf2-ARE/hMAO-B/QR2调节剂1在急性和慢性阿尔茨海默症模型中使用海马组织发挥神经保护和抗氧化作用。

化合物

cis-trismethoxy Resveratrol

Cat.No: T3330L

Synonym: (Z)-3,5,4'-Trimethoxystilbene,顺式白藜芦醇三甲醚

Target: Microtubule Associated

Cat.No: T5541

Synonym: 1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth,PDM 11

Target: AhR

Glycyrrhizinic acid, potassium salt

Cat.No: T7827

Target: Others

Cat.No: T3585

Synonym: (E)-2,3',4,5'-tetramethoxystilbene,2,3',4,5'-Tetramethoxystilbene

Target: P450

Cat.No: T36674

Target: Apoptosis, ERK

Cat.No: T12781

Target: Others

Resveratrol-4'-O-D-Glucuronide

Cat.No: T36518

Cat.No: T74841

Nrf2-ARE/hMAO-B/QR2 modulator 1

Cat.No: T60395

Cat. No.	Product Name	Target	Signaling Pathways
T3840	Dihydroresveratrol 3,4',5-Trihydroxybibenzyl,二氢白藜芦醇,二氢藜芦醇	Estrogen Receptor/ERR; Others	Endocrinology/Hormones; Others
	Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) 是一种激素受体调节剂，是一种植物雌激素。它在皮摩尔和纳摩尔浓度下促进前列腺和乳腺癌细胞增殖。
T0657	Veratryl alcohol 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇	Others	Others
	Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) 是木质素降解真菌的次级代谢产物，通常作为非酚性底物测定木质素分解活性。
T5668	Triacetylresveratrol 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol	BCL; NF-κB; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	Triacetylresveratrol (Acetyl-trans-resveratrol) 是 Resveratrol 的乙酰化类似物，可降低 STAT3和 NF-κB 磷酸化，具有抗癌作用。
T5716	4'-Methoxyresveratrol 白藜芦醇-4'-甲醚,4'-O-Methylresveratrol	advanced glycation end products	Others
	4'-Methoxyresveratrol (4'-O-Methylresveratrol) 是一种多酚类化合物，来源于双翅目植物中，具有抗雄激素、抗真菌和抗炎症作用。它能抑制 RAGE- 介导的 MAPK/NF-κB 信号通路，并激活 NLRP3 炎性体，从而缓解 AGE- 诱导的炎症。
T1558	Resveratrol 白藜芦醇,trans-Resveratrol,SRT 501	Apoptosis; Mitophagy; IκB/IKK; Lipoxygenase; Sirtuin; COX; NADPH; DNA/RNA Synthesis; Nrf2; Antibacterial; Antibiotic; Autophagy; Antifungal	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Resveratrol (SRT 501) 属于多酚类天然产物，是一种植物抗毒素，具有抗氧化和化学预防活性。Resveratrol 的靶点广泛，包括 COX、SIRT、LOC 等。Resveratrol 可以诱导细胞自噬和凋亡。
T11218	ε-Viniferin epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体	P450	Metabolism
	ε-Viniferin (epsilon-Viniferin) 提取自 Vitis vinifera，是 Resveratrol 的二聚体，能够抑制 CYP 家族,其 Ki=0.5~20 μM，具有抗氧化作用。
T3S1068	Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T3330	trans-Trimethoxyresveratrol trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	trans-Trimethoxyresveratrol (MR-3) 是一种 Resveratrol(RSV) 的衍生物，与Resveratrol(RSV)相比，它可能是一个更有效的抗炎、抗血管新生的化合物。
T37911	cis-Resveratrol 顺式白藜芦醇,(Z)-Resveratrol
	Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the &#181M range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase ...
TMA2415	4-Prenyloxyresveratrol 4-异戊烯基氧基白藜芦醇,4'-Prenyloxyresveratrol	Others	Others
	4'-Prenyloxyresveratrol is a natural product from Morus wittiorum.
TN2026	Oxyresveratrol 3'-O-β-D-glucopyranoside Oxyresveratrol 3'-O-beta-D-glucopyranoside,氧化白藜芦醇-3'-O-Β-D-吡喃葡萄糖苷	Tyrosinase	Proteases/Proteasome
	Oxyresveratrol-3'-O-beta-D-glucopyranoside shows tyrosinase inhibitory activity, it may be a potential candidate as skin-whitening agents without posing any serious side effects.
TN2025	Oxyresveratrol 2-O-β-D-glucopyranoside 氧化白藜芦醇-2-O-Β-D-吡喃葡萄糖苷,Oxyresveratrol 2-O-beta-D-glucopyranoside	Others; Tyrosinase	Others; Proteases/Proteasome
	Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
T124477	Resveratrol 4'-(6-galloylglucoside) Resveratrol-4'-O-(6"-galloyl)glucoside	Others	Others
	Resveratrol 4'-(6-galloylglucoside) (Resveratrol-4'-O-(6"-galloyl)glucoside)是一种天然产物，存在于植物掌叶大黄 rhubarb (Rheum palmatum L.)的根中。
TN2144	Resveratroloside	P450; NO Synthase	Immunology/Inflammation; Metabolism
	Resveratroloside 是α-glucosidase 的竞争性抑制剂，可以对血糖水平进行调节，对心脏具有保护作用。
TN3864	Dihydroresveratrol 3-O-glucoside	Others	Others
	Dihydroresveratrol 3-O-glucoside 是一种天然产物，存在于Camellia sinensis var. assamica (J.W. Mast.) Kitam.叶子。
TN5746	Gnetifolin E 买麻藤戊素	Others	Others
	Gnetifolin E 是一种新的白藜芦醇三聚体衍生物，来自 Gnetum brunonianum。
T3843	Pinosylvin 银松素,3,5-stilbenediol,5-Styrylresorcinol	Apoptosis; Others; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Others
	Pinosylvin (5-Styrylresorcinol) 是从Pinus spp 的心材中分离出来的一种白藜芦醇类似物，可诱导白血病细胞凋亡和自噬。它是一种感染前的类苯乙烯类毒素，具有抗菌活性。
T3776	Rhapontigenin 丹叶大黄素,Protigenin	P450; Antibacterial; Antifungal	Metabolism; Microbiology/Virology
	Rhapontigenin (Protigenin) 是一种基于机制的选择性细胞色素 P450 1A1 (IC50: 400 nM) 灭活剂。它是一种芳烃羟化酶，可激活作为致癌物质的多环芳烃。它是白藜芦醇的天然类似物，具有抗癌，抗氧化剂，抗真菌和抗菌活性。
T82262	Grandivine A
	Grandivine A, 类固醇生物碱, 源自毛叶藜芦 (Veratrum grandiflorum) 分离。

天然产物

Dihydroresveratrol

Cat.No: T3840

Synonym: 3,4',5-Trihydroxybibenzyl,二氢白藜芦醇,二氢藜芦醇

Target: Estrogen Receptor/ERR, Others

Veratryl alcohol

Cat.No: T0657

Synonym: 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇

Target: Others

Triacetylresveratrol

Cat.No: T5668

Synonym: 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol

Target: BCL, NF-κB, STAT

4'-Methoxyresveratrol

Cat.No: T5716

Synonym: 白藜芦醇-4'-甲醚,4'-O-Methylresveratrol

Target: advanced glycation end products

Cat.No: T1558

Synonym: 白藜芦醇,trans-Resveratrol,SRT 501

Target: Apoptosis, Mitophagy, IκB/IKK, Lipoxygenase, Sirtuin, COX, NADPH, DNA/RNA Synthesis, Nrf2, Antibacterial, Antibiotic, Autophagy, Antifungal

Cat.No: T11218

Synonym: epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体

Target: P450

Cat.No: T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

trans-Trimethoxyresveratrol

Cat.No: T3330

Synonym: trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene

Target: Reactive Oxygen Species

cis-Resveratrol

Cat.No: T37911

Synonym: 顺式白藜芦醇,(Z)-Resveratrol

4-Prenyloxyresveratrol

Cat.No: TMA2415

Synonym: 4-异戊烯基氧基白藜芦醇,4'-Prenyloxyresveratrol

Target: Others

Oxyresveratrol 3'-O-β-D-glucopyranoside

Cat.No: TN2026

Synonym: Oxyresveratrol 3'-O-beta-D-glucopyranoside,氧化白藜芦醇-3'-O-Β-D-吡喃葡萄糖苷

Target: Tyrosinase

Oxyresveratrol 2-O-β-D-glucopyranoside

Cat.No: TN2025

Synonym: 氧化白藜芦醇-2-O-Β-D-吡喃葡萄糖苷,Oxyresveratrol 2-O-beta-D-glucopyranoside

Target: Others, Tyrosinase

Resveratrol 4'-(6-galloylglucoside)

Cat.No: T124477

Synonym: Resveratrol-4'-O-(6"-galloyl)glucoside

Target: Others

Resveratroloside

Cat.No: TN2144

Target: P450, NO Synthase

Dihydroresveratrol 3-O-glucoside

Cat.No: TN3864

Target: Others

Cat.No: TN5746

Synonym: 买麻藤戊素

Target: Others

Cat.No: T3843

Synonym: 银松素,3,5-stilbenediol,5-Styrylresorcinol

Target: Apoptosis, Others, Antibacterial, Autophagy

Cat.No: T3776

Synonym: 丹叶大黄素,Protigenin

Target: P450, Antibacterial, Antifungal

Cat.No: T82262

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