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58

抑制剂 & 化合物

18

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Cat. No. Product Name Target Signaling Pathways
T34648 Sinitrodil

ITF296,ITF-296,ITF 296

Guanylate cyclase GPCR/G Protein
Sinitrodil (ITF-296) 是一种鸟苷酸环化酶兴奋剂,可用于治疗心肌缺血和心绞痛。
T0273 Mefexamide

美非沙胺盐酸盐,Mefaxadyne,美非沙胺,Timodyne,Mefexamide hydrochloride

Others Others
Mefexamide hydrochloride 是一种特殊的精神刺激剂。
T3269 Metadoxine

pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil,美他多辛

5-HT Receptor; PKA GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors
Metadoxine (Metadoxil) 能够阻断蛋白激酶 A- cAMP 反应原件结合蛋白通路,阻断脂肪细胞的分化。
T19991 N-desmethylmirtazapine

米氮平杂质D,N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838

Others Others
N-desmethylmirtazapine (J1.061.658A) 是mirtazapine 的代谢物。它也常用作抗焦虑药、催眠药、止吐药和食欲兴奋剂。
T1413 Pentetrazol

Metrazole,Pentylenetetrazole,Pentylenetetrazol,戊四唑,PTZ,pentamethylenetetrazol,Cardiazol

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Pentetrazol 是一种 GABA(A) 受体拮抗剂,具有中枢神经系统和呼吸兴奋剂的活性。
T2191 Tacrine hydrochloride (hydrate)

Tacrine,他克林盐酸盐水合物,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine

AChR; AChE Neuroscience
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) 是一种乙酰胆碱酯酶 (AChE) 和丁酰胆碱酯酶 (BChE) 的抑制剂,它们的IC50值分别为 31 nM 和 25.6 nM。
T0048 Nikethamide

N,N-Diethylnicotinamide,Corvotone,Anacardone,烟酰乙胺,Corvin

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Nikethamide 是呼吸中枢激活剂,可用于研究呼吸衰竭。
T1112 2-(Hydroxymethyl)pyridine

吡啶甲醇,Piconol

PDE Metabolism
2-(Hydroxymethyl)pyridine (Piconol) 可用作有机合成与医药化学中间体,用于刺激性泻药比沙可啶的合成,也可用作具有降血糖活性的吡啶醇。
T30686 Cafedrine

l-Cafedrine,Cafedrin

Others Others
Cafedrine (Cafedrin) 存在于茶叶和咖啡中,对中枢神经的兴奋作用。Cafedrine 常与可肾上腺素固定 20:1 组合来研究急性低血压。
T10830 CL 316243

Adrenergic Receptor GPCR/G Protein; Neuroscience
CL316243 是一种高效的 β3 肾上腺素受体选择性激动剂,EC50 为 3 nM。它是一种有效的脂肪细胞脂解刺激剂,可增加棕色脂肪组织的产热和代谢率,具有治疗肥胖症、糖尿病和急迫性尿失禁的潜力。
TQ0159 U-73343

U 73343

Phospholipase Metabolism
U-73343 是一种 U-73122 的无活性类似物,能够剂量依赖性的抑制酸分泌,可作为 U-73122 的阴性对照。其中 U 73122 是一种有效的磷脂酶 C (phospholipase C) 和 5-脂氧合酶 (5-LO (5-lipoxygenase)) 抑制剂,对磷脂酶 C 的 IC50值约为 1-2.1 µM。
T0869 Atomoxetine hydrochloride

Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,盐酸托莫西汀,LY 139603,Atomoxetine HCl,LY 139603 HCl

Dopamine Receptor; 5-HT Receptor; Norepinephrine GPCR/G Protein; Neuroscience
Atomoxetine hydrochloride (LY 139603) 是苯氧基-3-丙胺衍生物和选择性非兴奋剂,是去甲肾上腺素再摄取抑制剂,具有认知增强活性。 与人 NET,SERT 和 DAT 的放射性配体结合的 Ki 分别为5,77和1451 nM。
T24817 Otaplimastat

J3.046.690J,SP8203,SP-8203,SP 8203

SP-8203 is a reactive oxygen species inhibitor and superoxide dismutase stimulant.
T35153 Xamoterol

Xamoterolum

Xamoterol is a cardiac stimulant.
T68977 Picilorex

Picilorex is a monoamine reuptake inhibitor, a stimulant as well as a derivate of Pyrrolidine.
T32246 J-115814

J 115814J-115814, (+/-)-,UNII-81DP93CF8M

J-115814 is a potent feeding stimulant.
T30119 Arbutamine hydrochloride

Arbutamine hydrochloride is a catecholamine which acts as a cardiac stimulant.
T24164 Indanorex

JL-11698,Dietor,JL11698,Indanorexum,JL 11698

Indanorex is a stimulant drug. It has appetite suppressant effects and also has antihyperglycemic effects.
T31559 DO-601

DO-601 is a stimulant that stimulates the central nervous system.
T17298 Zylofuramine

Others Others
Zylofuramine is a stimulant of psychomotor.
T31266 Deanol glutamate

Deanol glutamate is a central stimulant.
T23996 Difemetorex

Diphemetoxidine,BA 18189,JB 8035,Difemetorexum,BRN 1651678

Difemetorex is a stimulant drug of the piperidine class which was used as an appetite suppressant.
T13142 Theodrenaline

(±)​-​Theodrenaline,茶碱那林

Others Others
Theodrenaline is a cardiac stimulant, also acts as an agent of anti-hypotensive together with cafedrine.
T34329 Rimiterol

Rimiterol, a beta 2 stimulant, therefore affects the cardiovascular system less than isoproterenol.
T32539L Laidlomycin propionate potassium

RS11988,RS 11988,RS-11988,Cattlyst

Laidlomycin propionate potassium is a growth stimulant (Veterinary).
T25499 Hexoprenaline

Hexoprenaline is a stimulant of adrenergic beta 2 receptors used as a bronchodilator, antiasthmatic agent, and tocolytic agent.
T17308 (R)-Oxiracetam

奥拉西坦,(R)-(+)-Oxiracetam

Others Others
(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant.
T16769 Ro 363

Adrenergic Receptor GPCR/G Protein; Neuroscience
RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is an effective and highly selective β1-adrenoceptor agonist.
T32343 JWU-A021

JWU A021

JWU-A021 is a particularly potent stimulant of glucagon-like peptides-1 (GLP-1) secretion in vivo.
T69494 Toliprolol

Toliprolol is an adrenergic receptor antagonist with some stimulant action; it has been proposed for angina pectoris.
T24801 SKF-77434, (S)-

S-(-)-Apd,J482.833J,S-(-)-SKF-77434

SKF-77,434 is a drug that acts as a selective dopamine D1 receptor partial agonist. It also has stimulant and anorectic effects.
T24641 Pimeclone hydrochloride

NU852,NSC 18727,NU 582,Pimeclone HCl,NU-582

Pimeclone hydrochloride is a psychostimulant or a respiratory stimulant drug.
T68848 Cilobamine mesylate

Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.
T33287 Mephentermine Sulfate

sulfuric acid,MLS002153976,N,2-dimethyl-1-phenylpropan-2-amine,AC1NWAW7,Mephentermine sodium

Mephentermine sulfate is a cardiac stimulant, before as a stimulant in psychiatry, has been used as a treatment for low blood pressure. Mephentermine sulfate is a sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maint
T31264 Deanol acetamidobenzoate

Deanol p-acetamidobenzoate,Elevan,Diforene,Cervoxan,Deaner

Deanol acetamidobenzoate is CNS stimulant. It can be caused elevated blood choline levels, can be used in Treatment of Choreiform Movement Disorders.
T72977 Cyprodenate

Actebral

Cyprodenate (Actebral) 是一种强心性脑兴奋剂,具有口服活性。Cyprodenate 可用于代谢研究。
T34302 Retroprogesterone

Retroprogesterone, a progestin, may be used for menstrual irregularities in adolescence, for the maintenance of threatened pregnancy, and possibly as an ovulation stimulant.
T20028 Janumet

Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate

Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator.
T29887 Aloe emodin anthrone

Aloe emodin anthrone is a stimulant-laxative which has been shown to enhance colonic membrane permeability of water-soluble and poorly permeable compounds.
T74442 Cytidine 5′-diphosphoethanolamine

Cytidine 5′-diphosphoethanolamine 是磷脂酰乙醇胺合成的中间体,也是乙酰胆碱合成的刺激剂。
T69406 Sydnophene

Sydnophene is an intermediate in the synthesis of metabolites of Mesocarb -- a CNS stimulant that acts as a dopamine reuptake inhibitor.
T10996 Deramciclane

EGIS-3886

5-HT Receptor GPCR/G Protein; Neuroscience
Deramciclane has high affinity for 5-HT2A and 5-HT2C receptors. It acts as an antagonist in both receptor subtypes and has inverse agonist properties for 5-HT2C receptors, but no direct stimulant agonists.
T21411L Isoproterenol bitartrate

Isoproterenol bitartrate is a beta-sympathomimetic and an isopropyl analog of Epinephrine, which acts on the heart, bronchi, skeletal muscle, and alimentary tract. It is used mainly as a bronchodilator and heart stimulant.
T31864 FPFS-1169 HCl

R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169

FPFS-1169 (BPAP-CPD, R-(-)-BPAP, R- FpFS-1169) is a proto-oncogene protein C-Bcl-2 stimulant that is one of the "catecholaminergic and serotonergic enhancers" and may be used for the treatment of Parkinson's disease.
T22315 Doxapram

Others Others
Doxapram, a central respiratory stimulant with a brief duration of action, is a selective TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel inhibitor with EC50 of 410 nM, 37 μM, 9 μM, respectively.
T68849 Cilobamine (free base)

Cilobamine (free base) is a drug which acts as a norepinephrine-dopamine reuptake inhibitor and has stimulant and antidepressant effects. It can clearly be seen that the structure is based on dichloroisoprenaline that has been fused onto the bicycloalkane scaffold.
T29213 Zelandopam free base

YM-435,YM435,MYD-37,MYD37,Zelandopam

Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodilating and diuretic/natriuretic effe
T79877 MTvkPABC-P5

MTvkPABC-P5d,作为TLR7激动剂,属于免疫刺激剂类。该化合物主要应用于合成免疫刺激抗体偶联物(ISAC)。
T14932L Ceruletide Ammonium acetate

FI-6934 Ammonium acetate,Caerulein Ammonium acetate,Ceruletide Ammonium acetate (17650-98-5 free base)

cholecystokinin GPCR/G Protein
Ceruletide Ammonium acetate (FI-6934 Ammonium acetate) 是一种胆囊收缩素 (CCK) 受体激动剂。它是一种安全有效的胆囊动力剂和小肠和胰腺外分泌兴奋剂。
T70625 Nicotine lactate

Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist.

化合物

Sinitrodil
Cat.No: T34648
Synonym: ITF296,ITF-296,ITF 296
Target: Guanylate cyclase
Mefexamide
Cat.No: T0273
Synonym: 美非沙胺盐酸盐,Mefaxadyne,美非沙胺,Timodyne,Mefexamide hydrochloride
Target: Others
Metadoxine
Cat.No: T3269
Synonym: pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil,美他多辛
Target: 5-HT Receptor, PKA
N-desmethylmirtazapine
Cat.No: T19991
Synonym: 米氮平杂质D,N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838
Target: Others
Pentetrazol
Cat.No: T1413
Synonym: Metrazole,Pentylenetetrazole,Pentylenetetrazol,戊四唑,PTZ,pentamethylenetetrazol,Cardiazol
Target: GABA Receptor
Tacrine hydrochloride (hydrate)
Cat.No: T2191
Synonym: Tacrine,他克林盐酸盐水合物,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine
Target: AChR, AChE
Nikethamide
Cat.No: T0048
Synonym: N,N-Diethylnicotinamide,Corvotone,Anacardone,烟酰乙胺,Corvin
Target: GABA Receptor
2-(Hydroxymethyl)pyridine
Cat.No: T1112
Synonym: 吡啶甲醇,Piconol
Target: PDE
Cafedrine
Cat.No: T30686
Synonym: l-Cafedrine,Cafedrin
Target: Others
CL 316243
Cat.No: T10830
Synonym:
Target: Adrenergic Receptor
U-73343
Cat.No: TQ0159
Synonym: U 73343
Target: Phospholipase
Atomoxetine hydrochloride
Cat.No: T0869
Synonym: Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,盐酸托莫西汀,LY 139603,Atomoxetine HCl,LY 139603 HCl
Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine
Otaplimastat
Cat.No: T24817
Synonym: J3.046.690J,SP8203,SP-8203,SP 8203
Target:
Xamoterol
Cat.No: T35153
Synonym: Xamoterolum
Target:
Picilorex
Cat.No: T68977
Synonym:
Target:
J-115814
Cat.No: T32246
Synonym: J 115814J-115814, (+/-)-,UNII-81DP93CF8M
Target:
Arbutamine hydrochloride
Cat.No: T30119
Synonym:
Target:
Indanorex
Cat.No: T24164
Synonym: JL-11698,Dietor,JL11698,Indanorexum,JL 11698
Target:
DO-601
Cat.No: T31559
Synonym:
Target:
Zylofuramine
Cat.No: T17298
Synonym:
Target: Others
Deanol glutamate
Cat.No: T31266
Synonym:
Target:
Difemetorex
Cat.No: T23996
Synonym: Diphemetoxidine,BA 18189,JB 8035,Difemetorexum,BRN 1651678
Target:
Theodrenaline
Cat.No: T13142
Synonym: (±)​-​Theodrenaline,茶碱那林
Target: Others
Rimiterol
Cat.No: T34329
Synonym:
Target:
Laidlomycin propionate potassium
Cat.No: T32539L
Synonym: RS11988,RS 11988,RS-11988,Cattlyst
Target:
Hexoprenaline
Cat.No: T25499
Synonym:
Target:
(R)-Oxiracetam
Cat.No: T17308
Synonym: 奥拉西坦,(R)-(+)-Oxiracetam
Target: Others
Ro 363
Cat.No: T16769
Synonym:
Target: Adrenergic Receptor
JWU-A021
Cat.No: T32343
Synonym: JWU A021
Target:
Toliprolol
Cat.No: T69494
Synonym:
Target:
SKF-77434, (S)-
Cat.No: T24801
Synonym: S-(-)-Apd,J482.833J,S-(-)-SKF-77434
Target:
Pimeclone hydrochloride
Cat.No: T24641
Synonym: NU852,NSC 18727,NU 582,Pimeclone HCl,NU-582
Target:
Cilobamine mesylate
Cat.No: T68848
Synonym:
Target:
Mephentermine Sulfate
Cat.No: T33287
Synonym: sulfuric acid,MLS002153976,N,2-dimethyl-1-phenylpropan-2-amine,AC1NWAW7,Mephentermine sodium
Target:
Deanol acetamidobenzoate
Cat.No: T31264
Synonym: Deanol p-acetamidobenzoate,Elevan,Diforene,Cervoxan,Deaner
Target:
Cyprodenate
Cat.No: T72977
Synonym: Actebral
Target:
Retroprogesterone
Cat.No: T34302
Synonym:
Target:
Janumet
Cat.No: T20028
Synonym: Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate
Target:
Aloe emodin anthrone
Cat.No: T29887
Synonym:
Target:
Cytidine 5′-diphosphoethanolamine
Cat.No: T74442
Synonym:
Target:
Sydnophene
Cat.No: T69406
Synonym:
Target:
Deramciclane
Cat.No: T10996
Synonym: EGIS-3886
Target: 5-HT Receptor
Isoproterenol bitartrate
Cat.No: T21411L
Synonym:
Target:
FPFS-1169 HCl
Cat.No: T31864
Synonym: R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169
Target:
Doxapram
Cat.No: T22315
Synonym:
Target: Others
Cilobamine (free base)
Cat.No: T68849
Synonym:
Target:
Zelandopam free base
Cat.No: T29213
Synonym: YM-435,YM435,MYD-37,MYD37,Zelandopam
Target:
MTvkPABC-P5
Cat.No: T79877
Synonym:
Target:
Ceruletide Ammonium acetate
Cat.No: T14932L
Synonym: FI-6934 Ammonium acetate,Caerulein Ammonium acetate,Ceruletide Ammonium acetate (17650-98-5 free base)
Target: cholecystokinin
Nicotine lactate
Cat.No: T70625
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T19189 Allocholic acid

Others Others
Allocholic acid 是一种胆汁酸,在脊椎动物中发现,在肝脏再生和致癌过程中会重新出现,也是成熟嗅觉系统的特定性刺激物。
T3S2197 Polygalic acid

Senegenic acid,远志皂甙

Others Others
Polygalic acid (Senegenic acid) 是一种三萜皂苷,是远志 (Polygala tenuifolia) 的一种主要活性成分。
T1396 Bemegride

贝美格,Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Bemegride (3-Ethyl-3-methylglutarimide) 是一种中枢神经系统兴奋剂和巴比妥类中毒的解毒剂。
T5940 Proxyphylline

羟丙茶碱,7-(2-Hydroxypropyl)theophylline

PDE; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Proxyphylline (7-(2-Hydroxypropyl)theophylline) 是甲基黄嘌呤衍生物,可用作心脏活化剂、血管扩张剂和支气管扩张剂。
T2205 Acefylline

Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid

TNF; PAD; PKA; HDAC; PDE; Adenosine Receptor Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
Acefylline (Theophylline-7-acetic acid) 是黄嘌呤衍生物,是一种腺苷受体拮抗剂。它是蛋白质精氨酸脱亚氨酶 (PAD) 激活剂,也是一种支气管扩张剂,可抑制大鼠肺 cAMP 磷酸二酯酶同工酶。
T2O2776 L-Valine

Others; Endogenous Metabolite Metabolism; Others
L-Valine 是蛋白二十种氨基酸中的其中一种。它是必需氨基酸。
T0965 Histamine

Ergamine,组胺

5-HT Receptor; Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Histamine (Ergamine) 是通过组胺的酶促脱羧衍生的胺。它是一种强大的胃分泌兴奋剂、支气管平滑肌的收缩剂、血管扩张剂以及中枢作用的神经递质。
T1083 Theophylline

Theo-24,1,3-Dimethylxanthine,茶碱

Endogenous Metabolite; HDAC; PDE; Adenosine Receptor; Autophagy Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Theophylline (1,3-Dimethylxanthine) 是茶中的甲基黄嘌呤衍生物,具有利尿、平滑肌松弛、支气管扩张、心脏和中枢神经系统兴奋作用。
T0771 Casanthranol

美鼠李皮蒽酚苷,鼠李蒽酚

Others Others
Casanthranol是从Rhamnus p.的干燥树皮(通常称为cascara sagrada)提取的高浓度的蒽酚苷混合物。Casanthranol 主要用于缓解便秘。Casanthranol通过其对肠壁的作用,促进肌肉收缩的增加,从而帮助肠道运动。
T6534 Histamine dihydrochloride

组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl

Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Histamine dihydrochloride (Ceplene) 是 Histamine 的二盐酸形式。Histamine 是一种有机氮化合物,是一种强效的胃分泌兴奋剂,支气管平滑肌收缩剂,血管舒张剂,也是一种中枢作用的神经递质。
T29888 Aloe-emodin-glucoside

Aloe-emodin-glucoside is a stimulant-laxative which has been shown to enhance colonic membrane permeability of water-soluble and poorly permeable compounds.
TN4718 Orobanchyl acetate

Others Others
Orobanchyl acetate is a germination stimulant for root parasitic plants.
T2S2363 Corydine

IL Receptor; Antifection Immunology/Inflammation; Microbiology/Virology
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial
T82300 Gluconasturtiin

Gluconasturtiin 作为P. maculipennis幼虫的摄食诱导剂,但其高浓度会对幼虫产生毒害效应。
TN3107 5-Deoxystrigol

Others Others
5-Deoxystrigol 是一种高活性的独脚金发芽刺激剂。对 D-半乳糖胺(D-GalN)诱导的小鼠急性肝损伤有保护作用,对 CCl4诱导的小鼠急性肝损伤有保护作用。
T80862 Vitamin B15 hemicalcium

Pangamic Acid hemicalcium

Vitamin B15 (Pangamic Acid) hemicalcium 是一种自然存在于植物种子中的化合物,具有促进细胞呼吸的作用。它包含了D-葡萄糖基二甲基氨基乙酸,并可作为免疫校正剂。Vitamin B15 hemicalcium 在多种疾病研究中有应用。
T10195 7-O-Geranylscopoletin

7-Geranyloxy-6-methoxycoumarin

Others Others
7-O-Geranylscopoletin is a natural coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, antispasmodic, paralysis, hemiplegia, and sti
TN5912 Macluraxanthone

3-Hydroxyblancoxanthone

Antioxidant; TNF Apoptosis; oxidation-reduction
Macluraxanthone (3-Hydroxyblancoxanthone) 具有许多生物活性,包括抗胆碱酯酶、抗氧化、抗癌、抗疟疾、抗炎和免疫调节作用。Macluraxanthone 通过增加表达CD86的巨噬细胞的百分比,同时减少其CD14、CD11b 和CD80的表达,来促进M1类促炎症巨噬细胞的极化。Macluraxanthone 在促炎症刺激物脂多糖的存在下明显减少了TNF-α和IL-10细胞因子的产生。

天然产物

Allocholic acid
Cat.No: T19189
Synonym:
Target: Others
Polygalic acid
Cat.No: T3S2197
Synonym: Senegenic acid,远志皂甙
Target: Others
Bemegride
Cat.No: T1396
Synonym: 贝美格,Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon
Target: GABA Receptor
Proxyphylline
Cat.No: T5940
Synonym: 羟丙茶碱,7-(2-Hydroxypropyl)theophylline
Target: PDE, Adenosine Receptor
Acefylline
Cat.No: T2205
Synonym: Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid
Target: TNF, PAD, PKA, HDAC, PDE, Adenosine Receptor
L-Valine
Cat.No: T2O2776
Synonym:
Target: Others, Endogenous Metabolite
Histamine
Cat.No: T0965
Synonym: Ergamine,组胺
Target: 5-HT Receptor, Endogenous Metabolite, Histamine Receptor
Theophylline
Cat.No: T1083
Synonym: Theo-24,1,3-Dimethylxanthine,茶碱
Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy
Casanthranol
Cat.No: T0771
Synonym: 美鼠李皮蒽酚苷,鼠李蒽酚
Target: Others
Histamine dihydrochloride
Cat.No: T6534
Synonym: 组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl
Target: Endogenous Metabolite, Histamine Receptor
Aloe-emodin-glucoside
Cat.No: T29888
Synonym:
Target:
Orobanchyl acetate
Cat.No: TN4718
Synonym:
Target: Others
Corydine
Cat.No: T2S2363
Synonym:
Target: IL Receptor, Antifection
Gluconasturtiin
Cat.No: T82300
Synonym:
Target:
5-Deoxystrigol
Cat.No: TN3107
Synonym:
Target: Others
Vitamin B15 hemicalcium
Cat.No: T80862
Synonym: Pangamic Acid hemicalcium
Target:
7-O-Geranylscopoletin
Cat.No: T10195
Synonym: 7-Geranyloxy-6-methoxycoumarin
Target: Others
Macluraxanthone
Cat.No: TN5912
Synonym: 3-Hydroxyblancoxanthone
Target: Antioxidant, TNF
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