58
18
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T34648 |
Sinitrodil
ITF296,ITF-296,ITF 296 |
Guanylate cyclase | GPCR/G Protein |
Sinitrodil (ITF-296) 是一种鸟苷酸环化酶兴奋剂,可用于治疗心肌缺血和心绞痛。 | |||
T0273 |
Mefexamide
美非沙胺盐酸盐,Mefaxadyne,美非沙胺,Timodyne,Mefexamide hydrochloride |
Others | Others |
Mefexamide hydrochloride 是一种特殊的精神刺激剂。 | |||
T3269 |
Metadoxine
pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil,美他多辛 |
5-HT Receptor; PKA | GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors |
Metadoxine (Metadoxil) 能够阻断蛋白激酶 A- cAMP 反应原件结合蛋白通路,阻断脂肪细胞的分化。 | |||
T19991 |
N-desmethylmirtazapine
米氮平杂质D,N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838 |
Others | Others |
N-desmethylmirtazapine (J1.061.658A) 是mirtazapine 的代谢物。它也常用作抗焦虑药、催眠药、止吐药和食欲兴奋剂。 | |||
T1413 |
Pentetrazol
Metrazole,Pentylenetetrazole,Pentylenetetrazol,戊四唑,PTZ,pentamethylenetetrazol,Cardiazol |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Pentetrazol 是一种 GABA(A) 受体拮抗剂,具有中枢神经系统和呼吸兴奋剂的活性。 | |||
T2191 |
Tacrine hydrochloride (hydrate)
Tacrine,他克林盐酸盐水合物,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine |
AChR; AChE | Neuroscience |
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) 是一种乙酰胆碱酯酶 (AChE) 和丁酰胆碱酯酶 (BChE) 的抑制剂,它们的IC50值分别为 31 nM 和 25.6 nM。 | |||
T0048 |
Nikethamide
N,N-Diethylnicotinamide,Corvotone,Anacardone,烟酰乙胺,Corvin |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Nikethamide 是呼吸中枢激活剂,可用于研究呼吸衰竭。 | |||
T1112 |
2-(Hydroxymethyl)pyridine
吡啶甲醇,Piconol |
PDE | Metabolism |
2-(Hydroxymethyl)pyridine (Piconol) 可用作有机合成与医药化学中间体,用于刺激性泻药比沙可啶的合成,也可用作具有降血糖活性的吡啶醇。 | |||
T30686 |
Cafedrine
l-Cafedrine,Cafedrin |
Others | Others |
Cafedrine (Cafedrin) 存在于茶叶和咖啡中,对中枢神经的兴奋作用。Cafedrine 常与可肾上腺素固定 20:1 组合来研究急性低血压。 | |||
T10830 |
CL 316243
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
CL316243 是一种高效的 β3 肾上腺素受体选择性激动剂,EC50 为 3 nM。它是一种有效的脂肪细胞脂解刺激剂,可增加棕色脂肪组织的产热和代谢率,具有治疗肥胖症、糖尿病和急迫性尿失禁的潜力。 | |||
TQ0159 |
U-73343
U 73343 |
Phospholipase | Metabolism |
U-73343 是一种 U-73122 的无活性类似物,能够剂量依赖性的抑制酸分泌,可作为 U-73122 的阴性对照。其中 U 73122 是一种有效的磷脂酶 C (phospholipase C) 和 5-脂氧合酶 (5-LO (5-lipoxygenase)) 抑制剂,对磷脂酶 C 的 IC50值约为 1-2.1 µM。 | |||
T0869 |
Atomoxetine hydrochloride
Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,盐酸托莫西汀,LY 139603,Atomoxetine HCl,LY 139603 HCl |
Dopamine Receptor; 5-HT Receptor; Norepinephrine | GPCR/G Protein; Neuroscience |
Atomoxetine hydrochloride (LY 139603) 是苯氧基-3-丙胺衍生物和选择性非兴奋剂,是去甲肾上腺素再摄取抑制剂,具有认知增强活性。 与人 NET,SERT 和 DAT 的放射性配体结合的 Ki 分别为5,77和1451 nM。 | |||
T24817 |
Otaplimastat
J3.046.690J,SP8203,SP-8203,SP 8203 |
||
SP-8203 is a reactive oxygen species inhibitor and superoxide dismutase stimulant. | |||
T35153 |
Xamoterol
Xamoterolum |
||
Xamoterol is a cardiac stimulant. | |||
T68977 | Picilorex | ||
Picilorex is a monoamine reuptake inhibitor, a stimulant as well as a derivate of Pyrrolidine. | |||
T32246 |
J-115814
J 115814J-115814, (+/-)-,UNII-81DP93CF8M |
||
J-115814 is a potent feeding stimulant. | |||
T30119 |
Arbutamine hydrochloride
|
||
Arbutamine hydrochloride is a catecholamine which acts as a cardiac stimulant. | |||
T24164 |
Indanorex
JL-11698,Dietor,JL11698,Indanorexum,JL 11698 |
||
Indanorex is a stimulant drug. It has appetite suppressant effects and also has antihyperglycemic effects. | |||
T31559 |
DO-601
|
||
DO-601 is a stimulant that stimulates the central nervous system. | |||
T17298 |
Zylofuramine
|
Others | Others |
Zylofuramine is a stimulant of psychomotor. | |||
T31266 |
Deanol glutamate
|
||
Deanol glutamate is a central stimulant. | |||
T23996 |
Difemetorex
Diphemetoxidine,BA 18189,JB 8035,Difemetorexum,BRN 1651678 |
||
Difemetorex is a stimulant drug of the piperidine class which was used as an appetite suppressant. | |||
T13142 |
Theodrenaline
(±)-Theodrenaline,茶碱那林 |
Others | Others |
Theodrenaline is a cardiac stimulant, also acts as an agent of anti-hypotensive together with cafedrine. | |||
T34329 |
Rimiterol
|
||
Rimiterol, a beta 2 stimulant, therefore affects the cardiovascular system less than isoproterenol. | |||
T32539L |
Laidlomycin propionate potassium
RS11988,RS 11988,RS-11988,Cattlyst |
||
Laidlomycin propionate potassium is a growth stimulant (Veterinary). | |||
T25499 |
Hexoprenaline
|
||
Hexoprenaline is a stimulant of adrenergic beta 2 receptors used as a bronchodilator, antiasthmatic agent, and tocolytic agent. | |||
T17308 |
(R)-Oxiracetam
奥拉西坦,(R)-(+)-Oxiracetam |
Others | Others |
(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant. | |||
T16769 |
Ro 363
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is an effective and highly selective β1-adrenoceptor agonist. | |||
T32343 |
JWU-A021
JWU A021 |
||
JWU-A021 is a particularly potent stimulant of glucagon-like peptides-1 (GLP-1) secretion in vivo. | |||
T69494 |
Toliprolol
|
||
Toliprolol is an adrenergic receptor antagonist with some stimulant action; it has been proposed for angina pectoris. | |||
T24801 |
SKF-77434, (S)-
S-(-)-Apd,J482.833J,S-(-)-SKF-77434 |
||
SKF-77,434 is a drug that acts as a selective dopamine D1 receptor partial agonist. It also has stimulant and anorectic effects. | |||
T24641 |
Pimeclone hydrochloride
NU852,NSC 18727,NU 582,Pimeclone HCl,NU-582 |
||
Pimeclone hydrochloride is a psychostimulant or a respiratory stimulant drug. | |||
T68848 |
Cilobamine mesylate
|
||
Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects. | |||
T33287 |
Mephentermine Sulfate
sulfuric acid,MLS002153976,N,2-dimethyl-1-phenylpropan-2-amine,AC1NWAW7,Mephentermine sodium |
||
Mephentermine sulfate is a cardiac stimulant, before as a stimulant in psychiatry, has been used as a treatment for low blood pressure. Mephentermine sulfate is a sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maint | |||
T31264 |
Deanol acetamidobenzoate
Deanol p-acetamidobenzoate,Elevan,Diforene,Cervoxan,Deaner |
||
Deanol acetamidobenzoate is CNS stimulant. It can be caused elevated blood choline levels, can be used in Treatment of Choreiform Movement Disorders. | |||
T72977 |
Cyprodenate
Actebral |
||
Cyprodenate (Actebral) 是一种强心性脑兴奋剂,具有口服活性。Cyprodenate 可用于代谢研究。 | |||
T34302 |
Retroprogesterone
|
||
Retroprogesterone, a progestin, may be used for menstrual irregularities in adolescence, for the maintenance of threatened pregnancy, and possibly as an ovulation stimulant. | |||
T20028 |
Janumet
Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate |
||
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. | |||
T29887 |
Aloe emodin anthrone
|
||
Aloe emodin anthrone is a stimulant-laxative which has been shown to enhance colonic membrane permeability of water-soluble and poorly permeable compounds. | |||
T74442 |
Cytidine 5′-diphosphoethanolamine
|
||
Cytidine 5′-diphosphoethanolamine 是磷脂酰乙醇胺合成的中间体,也是乙酰胆碱合成的刺激剂。 | |||
T69406 |
Sydnophene
|
||
Sydnophene is an intermediate in the synthesis of metabolites of Mesocarb -- a CNS stimulant that acts as a dopamine reuptake inhibitor. | |||
T10996 |
Deramciclane
EGIS-3886 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Deramciclane has high affinity for 5-HT2A and 5-HT2C receptors. It acts as an antagonist in both receptor subtypes and has inverse agonist properties for 5-HT2C receptors, but no direct stimulant agonists. | |||
T21411L |
Isoproterenol bitartrate
|
||
Isoproterenol bitartrate is a beta-sympathomimetic and an isopropyl analog of Epinephrine, which acts on the heart, bronchi, skeletal muscle, and alimentary tract. It is used mainly as a bronchodilator and heart stimulant. | |||
T31864 |
FPFS-1169 HCl
R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169 |
||
FPFS-1169 (BPAP-CPD, R-(-)-BPAP, R- FpFS-1169) is a proto-oncogene protein C-Bcl-2 stimulant that is one of the "catecholaminergic and serotonergic enhancers" and may be used for the treatment of Parkinson's disease. | |||
T22315 |
Doxapram
|
Others | Others |
Doxapram, a central respiratory stimulant with a brief duration of action, is a selective TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel inhibitor with EC50 of 410 nM, 37 μM, 9 μM, respectively. | |||
T68849 | Cilobamine (free base) | ||
Cilobamine (free base) is a drug which acts as a norepinephrine-dopamine reuptake inhibitor and has stimulant and antidepressant effects. It can clearly be seen that the structure is based on dichloroisoprenaline that has been fused onto the bicycloalkane scaffold. | |||
T29213 |
Zelandopam free base
YM-435,YM435,MYD-37,MYD37,Zelandopam |
||
Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodilating and diuretic/natriuretic effe | |||
T79877 |
MTvkPABC-P5
|
||
MTvkPABC-P5d,作为TLR7激动剂,属于免疫刺激剂类。该化合物主要应用于合成免疫刺激抗体偶联物(ISAC)。 | |||
T14932L |
Ceruletide Ammonium acetate
FI-6934 Ammonium acetate,Caerulein Ammonium acetate,Ceruletide Ammonium acetate (17650-98-5 free base) |
cholecystokinin | GPCR/G Protein |
Ceruletide Ammonium acetate (FI-6934 Ammonium acetate) 是一种胆囊收缩素 (CCK) 受体激动剂。它是一种安全有效的胆囊动力剂和小肠和胰腺外分泌兴奋剂。 | |||
T70625 |
Nicotine lactate
|
||
Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19189 |
Allocholic acid
|
Others | Others |
Allocholic acid 是一种胆汁酸,在脊椎动物中发现,在肝脏再生和致癌过程中会重新出现,也是成熟嗅觉系统的特定性刺激物。 | |||
T3S2197 |
Polygalic acid
Senegenic acid,远志皂甙 |
Others | Others |
Polygalic acid (Senegenic acid) 是一种三萜皂苷,是远志 (Polygala tenuifolia) 的一种主要活性成分。 | |||
T1396 |
Bemegride
贝美格,Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Bemegride (3-Ethyl-3-methylglutarimide) 是一种中枢神经系统兴奋剂和巴比妥类中毒的解毒剂。 | |||
T5940 |
Proxyphylline
羟丙茶碱,7-(2-Hydroxypropyl)theophylline |
PDE; Adenosine Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Proxyphylline (7-(2-Hydroxypropyl)theophylline) 是甲基黄嘌呤衍生物,可用作心脏活化剂、血管扩张剂和支气管扩张剂。 | |||
T2205 |
Acefylline
Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid |
TNF; PAD; PKA; HDAC; PDE; Adenosine Receptor | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors |
Acefylline (Theophylline-7-acetic acid) 是黄嘌呤衍生物,是一种腺苷受体拮抗剂。它是蛋白质精氨酸脱亚氨酶 (PAD) 激活剂,也是一种支气管扩张剂,可抑制大鼠肺 cAMP 磷酸二酯酶同工酶。 | |||
T2O2776 |
L-Valine
|
Others; Endogenous Metabolite | Metabolism; Others |
L-Valine 是蛋白二十种氨基酸中的其中一种。它是必需氨基酸。 | |||
T0965 |
Histamine
Ergamine,组胺 |
5-HT Receptor; Endogenous Metabolite; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Histamine (Ergamine) 是通过组胺的酶促脱羧衍生的胺。它是一种强大的胃分泌兴奋剂、支气管平滑肌的收缩剂、血管扩张剂以及中枢作用的神经递质。 | |||
T1083 |
Theophylline
Theo-24,1,3-Dimethylxanthine,茶碱 |
Endogenous Metabolite; HDAC; PDE; Adenosine Receptor; Autophagy | Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience |
Theophylline (1,3-Dimethylxanthine) 是茶中的甲基黄嘌呤衍生物,具有利尿、平滑肌松弛、支气管扩张、心脏和中枢神经系统兴奋作用。 | |||
T0771 |
Casanthranol
美鼠李皮蒽酚苷,鼠李蒽酚 |
Others | Others |
Casanthranol是从Rhamnus p.的干燥树皮(通常称为cascara sagrada)提取的高浓度的蒽酚苷混合物。Casanthranol 主要用于缓解便秘。Casanthranol通过其对肠壁的作用,促进肌肉收缩的增加,从而帮助肠道运动。 | |||
T6534 |
Histamine dihydrochloride
组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl |
Endogenous Metabolite; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Histamine dihydrochloride (Ceplene) 是 Histamine 的二盐酸形式。Histamine 是一种有机氮化合物,是一种强效的胃分泌兴奋剂,支气管平滑肌收缩剂,血管舒张剂,也是一种中枢作用的神经递质。 | |||
T29888 |
Aloe-emodin-glucoside
|
||
Aloe-emodin-glucoside is a stimulant-laxative which has been shown to enhance colonic membrane permeability of water-soluble and poorly permeable compounds. | |||
TN4718 |
Orobanchyl acetate
|
Others | Others |
Orobanchyl acetate is a germination stimulant for root parasitic plants. | |||
T2S2363 |
Corydine
|
IL Receptor; Antifection | Immunology/Inflammation; Microbiology/Virology |
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial | |||
T82300 |
Gluconasturtiin
|
||
Gluconasturtiin 作为P. maculipennis幼虫的摄食诱导剂,但其高浓度会对幼虫产生毒害效应。 | |||
TN3107 |
5-Deoxystrigol
|
Others | Others |
5-Deoxystrigol 是一种高活性的独脚金发芽刺激剂。对 D-半乳糖胺(D-GalN)诱导的小鼠急性肝损伤有保护作用,对 CCl4诱导的小鼠急性肝损伤有保护作用。 | |||
T80862 |
Vitamin B15 hemicalcium
Pangamic Acid hemicalcium |
||
Vitamin B15 (Pangamic Acid) hemicalcium 是一种自然存在于植物种子中的化合物,具有促进细胞呼吸的作用。它包含了D-葡萄糖基二甲基氨基乙酸,并可作为免疫校正剂。Vitamin B15 hemicalcium 在多种疾病研究中有应用。 | |||
T10195 |
7-O-Geranylscopoletin
7-Geranyloxy-6-methoxycoumarin |
Others | Others |
7-O-Geranylscopoletin is a natural coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, antispasmodic, paralysis, hemiplegia, and sti | |||
TN5912 |
Macluraxanthone
3-Hydroxyblancoxanthone |
Antioxidant; TNF | Apoptosis; oxidation-reduction |
Macluraxanthone (3-Hydroxyblancoxanthone) 具有许多生物活性,包括抗胆碱酯酶、抗氧化、抗癌、抗疟疾、抗炎和免疫调节作用。Macluraxanthone 通过增加表达CD86的巨噬细胞的百分比,同时减少其CD14、CD11b 和CD80的表达,来促进M1类促炎症巨噬细胞的极化。Macluraxanthone 在促炎症刺激物脂多糖的存在下明显减少了TNF-α和IL-10细胞因子的产生。 |