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41

抑制剂 & 化合物

32

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP2411	Sperm-activating peptide 1
	Sperm-activating peptide 1 is a bioactive chemical.
TP2410	Sperm acrosomal peptide P23 Val-ala-lys-lys-pro-lys
	Sperm acrosomal peptide P23 is a peptide obtained from sperm acrosomal protein.
T25049	Allethrin	BCL; Caspase	Apoptosis; Proteases/Proteasome
	Allethrin 是拟除虫菊酯杀虫剂，是主要的驱蚊剂。它在大鼠睾丸癌细胞 (LC540) 中诱导氧化应激、细胞凋亡和钙释放。它还诱导 BCL-2、caspase-3 激活和细胞内钙的释放。
T22260	Aminopurvalanol A	CDK	Cell Cycle/Checkpoint
	Aminopurvalanol A 是一种竞争性、选择性和细胞渗透性的Cyclins/Cdk 复合物抑制剂，优先靶向G2/M 期转变进而抑制癌细胞分化。它通过抑制生理获能依赖性肌动蛋白聚合而抑制精子受精能力。
T19461	N1,N8-Diacetylspermidine	Endogenous Metabolite	Metabolism
	N1,N8-Diacetylspermidine 是人尿中的一种多胺。N1,N8-Diacetylspermidine 可用作癌症和恶性肿瘤的标记物。
T9640	Diethylnorspermine HCl Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride	Others	Others
	Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) 可有效诱导 SSAT (亚精胺/精胺N1-乙酰转移酶) mRNA，并有效稳定 SSAT 酶活性。
T60066	thermospermine N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine,1,12-Diamino-4,8-diazadodecane	Others	Others
	Thermospermine 是精胺的结构异构体，在抑制木质部分化中发挥作用。Thermospermine 可用于作为植物生长调节剂和控制木材生物质生产的研究。
T37170	N1-Acetylspermidine hydrochloride N1-Acetylspermidine (hydrochloride)	Endogenous Metabolite	Metabolism
	N1-Acetylspermidine hydrochloride 是亚精胺的乙酰基衍生物。 N1-Acetylspermidine hydrochloride 是多胺氧化酶的底物，可选择性地提高其在人结直肠腺癌中的水平。
T36416	N1-Acetylspermine trihydrochloride N1-Acetylspermine (hydrochloride)	Others	Others
	N1-Acetylspermine trihydrochloride 是精胺的单乙酰化衍生物，精胺是一种内源性多胺。 N1-Acetylspermine trihydrochloride 可用于研究人体肉毒碱转运蛋白 SLC22A16 对抗癌多胺类似物博莱霉素 A5 的摄取。
T32211	Isoleptospermone
	Isoleptospermone is a bioactive chemical.
T129440	Aspermytin A
	Aspermytin A 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T129440。
T27171	Diethylhomospermine DEHOP,BE-4-4-4,DEHSPM,DE-444
	Diethylhomospermine is a drug potentially for the treatment of AIDS-related chronic diarrhea.Diethylhomospermine also shows promising anticancer activity.
T69600	Spermidine-d6
	Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µM) inhibits the activity of the human inward-rectifying potassium channel Kir2.3 in a patch-clamp assay. It induces autophagy in HeLa cells when used at a concentration of 100 µM and increases the lifespan of D. melanogaster, yeast, and C. elegans. Spermidine (30 mM in the drinki...
T31554	DNA-Spermidine DA-51,DA 51,DA51,DNA Spermidine
	DNA-spermidine influences the activity of restricted endonuclease from several bacterial species.
T70805	Diethylnorspermine HBr
	Diethylnorspermine, also known as DENSPM, BE-333, DE-333 and N(1),N(11)-Diethylnorspermine, is a highly potent known inducer of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT). A designed polyamines (PAs) analog which induces cell cycle arrest, inhibits proliferation and induces apoptosis in melanoma, breast, prostate, lung and colon cancer cells..
T32654	Leptospermone
	Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).
T130733	N1,N5,N10,N14-Tetra-trans-p-coumaroylspermine
	N1,N5,N10,N14-Tetra-trans-p-coumaroylspermine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T130733。
T125126	Urospermal
	Urospermal 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125126，CAS号为 28400-14-8。
T19460	N1,N8-Diacetylspermidine hydrochloride	Others	Others
	N1,N8-Diacetylspermidine hydrochloride is a polyamines in the human urine.
T60348	N1,N11-Diethylnorspermine
	N1,N11-Diethylnorspermine (DENSPM) 是一种有效的抗癌剂。N1,N11-Diethylnorspermine 是一种精胺类似物,可激活多胺分解代谢。N1,N11-Diethylnorspermine 诱导细胞色素 c 从线粒体中释放，导致 caspase 3的激活。N1,N11-Diethylnorspermine 通过诱导亚精胺/精胺 N1- 乙酰转移酶 (SSAT) 结合产生过氧化氢杀灭多形胶质母细胞瘤 (GBM) 细胞。
T23036	N-(4-Hydroxyphenylacetyl)spermine	Others	Others
	N-(4-Hydroxyphenylacetyl)spermine is a NMDA receptor antagonist.
T30196	Atherospermidine
	Atherospermidine is a smooth muscle relaxant aporphines from Artabotrys maingayi.
T64076	Spermine Prodrug-1
	Spermine Prodrug-1 是一种氧化还原敏感的精胺前药。Spermine Prodrug-1 对野生型 (CMS-24949) 和精胺合酶基因 (SMS) 突变型 (CMS-26559, 和 CMS-6233) 成纤维细胞具有抑制作用，他们的 IC50 值分别为 326.7, 198.5, 和 244.1 μM。Spermine Prodrug-1 能够用于 Snyder Robinson 综合征的治疗。
T74655	Glutathionylspermidine
	Glutathionylspermidine 是一种多肽，也是大肠杆菌代谢物。
T73767	N1-Acetylspermine
	N1-Acetylspermine 是存在于尿中的内源代谢物，可用于研究白血病。
T40887	N1,N12-Diacetylspermine dihydrochloride N1,N12-Diacetylspermine dihydrochloride,Diacetylspermine 2HCl	Endogenous Metabolite	Metabolism
	N1,N12-Diacetylspermine dihydrochloride (Diacetylspermine 2HCl) 是 Spermine 的二乙酰化衍生物。癌症的发生与 N1,N12-Diacetylspermine dihydrochloride 的上调有关，使其成为检测癌症发生的生物标记物。
T124265	Acanthospermolide
	Acanthospermolide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124265，CAS号为 75744-64-8。
T7487L	Speract TFA(76901-59-2(free base))	Others	Others
	Speract TFA(76901-59-2(free base)) 是一种海胆卵肽，可调节精子活力，也可刺激精子线粒体代谢。
T76373L	Ser-Ala-alloresact acetate Ser-Ala-alloresact acetate(140653-27-6 Free base)	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Ser-Ala-alloresact acetate是一种由海洋无脊椎动物卵释放的精子活化肽(SAP)，在受精过程中扮演重要角色。
T28174	Niridazole BA32644,BA-32644,Ambilhar,BA 32644
	Niridazole (Ambilhar) 是一种具有抗寄生虫活性的化合物，属于硝基咪唑类化合物。Niridazole 主要用于治疗血吸虫病，通过干扰寄生虫的新陈代谢，导致其死亡。Niridazole 在寄生虫体内迅速集中，抑制卵子和精子的发生，抑制磷酸果糖激酶活性。
T28082	Mollugogenol A
	Mollugogenol A is a Gammacerane from Mollugo pentaphylla. It is an antifungal saponin with spermatocidal activity. Mollugogenol A also involves sperm membrane damage by increased lipid peroxidation.
T40550	Human β-defensin-1 Human β-defensin-1,HβD-1
	Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by epithelial surfaces, circulatory cells, and cells of the reproductive tract. It exhibits antimicrobial activity against a wide range of sperm bacteria.
T7487	Speract 精子活化肽	Others; Mitochondrial Metabolism	Metabolism; Others
	Speract 是调节精子活力的海胆蛋肽，也能够刺激精子线粒体代谢。
T10810	Chromomycin A3	Others	Others
	Chromomycin A3 is an aureolic acid-type antitumor antibiotic. Chromomycin A3 has a variety of utilities as a staining agent for human sperm chromatin, autophagy inducing agent, and apoptosis inhibitor.
T76373	Ser-Ala-alloresact
	Ser-Ala-alloresact，一种精子激活肽(SAP)，在海洋无脊椎动物卵释放过程中对受精起着关键作用的多肽。
T71913	Bourgeonal
	Bourgeonal is an agonist of human testicular olfactory receptor hOR17-4. It increases cytosolic calcium levels in human spermatozoa, acts as a chemoattractant, and increases swimming speed in sperm chemotaxis assays in a concentration-dependent manner.
T70252	RU1968 bis-TFA salt
	RU1968 bis-TFA salt is an inhibitor of the sperm-specific Ca2+ channel CatSper, thereby inhibiting human Slo3 with about 15-fold lower potency than CatSper.
T83960	VU 0546110
	VU 0546110 是一种针对精子特异性钾通道 SLO3 的选择性抑制剂（IC50= 64 μM），相较于 SLO1 显示出 40 倍的选择性。它能完全阻断异源性 SLO3 电流和内源性 K+ 电流。VU 0546110 抑制精子超极化并阻止其超活跃移动。
T36781	st-Ht31 P st-Ht31 P
	Negative control for st-Ht31 . Gorshkov et al (2017) AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat.Chem.Biol. 13 425 PMID:28192412 \|Vijayaraghavan et al (1997) Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J.Biol.Chem. 272 4747 PMID:9030527 \|Vincent et al (2017) Signaling: Spatial regulation of axonal cAMP. Nat.Chem.Biol. 13 348 PMID:28328917
T69215	Ambrein
	Ambrein is a triterpene alcohol that is the chief constituent of ambergris, a secretion from the digestive system of the sperm whale, and has been suggested as the possible active component producing the supposed aphrodisiac effects of ambergris. It serves as the biological precursor for a number of aromatic derivatives such as ambroxan and is thought to possess fixative properties for other odorants. It has been shown to act as an analgesic and it has been proven to increase sexual behavior in ...
T83683	st-Ht31 ammonium sHt31
	st-Ht31是一种由A-kinase锚定蛋白（AKAPs）的两亲螺旋域衍生的、可穿透细胞的硬脂化肽，它能够结合蛋白激酶A (PKA)。在使用50 µM浓度时，能降低PKA在细胞膜上的锚定，但不影响其在使用BHK-21成纤维细胞进行的报告基因分析中的活性。st-Ht31 (1和3 µM)能减少小鼠精子的电容和超活化，同时阻止体外受精。当使用50 µM浓度时，它还能促进表达ATP结合盒转运蛋白1 (ABCA1)的BHK-21细胞和RAW 264.7巨噬细胞中的胆固醇排出。

化合物

Sperm-activating peptide 1

Cat.No: TP2411

Sperm acrosomal peptide P23

Cat.No: TP2410

Synonym: Val-ala-lys-lys-pro-lys

Cat.No: T25049

Target: BCL, Caspase

Aminopurvalanol A

Cat.No: T22260

Target: CDK

N1,N8-Diacetylspermidine

Cat.No: T19461

Target: Endogenous Metabolite

Diethylnorspermine HCl

Cat.No: T9640

Synonym: Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride

Target: Others

Cat.No: T60066

Synonym: N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine,1,12-Diamino-4,8-diazadodecane

Target: Others

N1-Acetylspermidine hydrochloride

Cat.No: T37170

Synonym: N1-Acetylspermidine (hydrochloride)

Target: Endogenous Metabolite

N1-Acetylspermine trihydrochloride

Cat.No: T36416

Synonym: N1-Acetylspermine (hydrochloride)

Target: Others

Isoleptospermone

Cat.No: T32211

Cat.No: T129440

Diethylhomospermine

Cat.No: T27171

Synonym: DEHOP,BE-4-4-4,DEHSPM,DE-444

Spermidine-d6

Cat.No: T69600

DNA-Spermidine

Cat.No: T31554

Synonym: DA-51,DA 51,DA51,DNA Spermidine

Diethylnorspermine HBr

Cat.No: T70805

Cat.No: T32654

N1,N5,N10,N14-Tetra-trans-p-coumaroylspermine

Cat.No: T130733

Cat.No: T125126

N1,N8-Diacetylspermidine hydrochloride

Cat.No: T19460

Target: Others

N1,N11-Diethylnorspermine

Cat.No: T60348

N-(4-Hydroxyphenylacetyl)spermine

Cat.No: T23036

Target: Others

Atherospermidine

Cat.No: T30196

Spermine Prodrug-1

Cat.No: T64076

Glutathionylspermidine

Cat.No: T74655

N1-Acetylspermine

Cat.No: T73767

N1,N12-Diacetylspermine dihydrochloride

Cat.No: T40887

Synonym: N1,N12-Diacetylspermine dihydrochloride,Diacetylspermine 2HCl

Target: Endogenous Metabolite

Acanthospermolide

Cat.No: T124265

Speract TFA(76901-59-2(free base))

Cat.No: T7487L

Target: Others

Ser-Ala-alloresact acetate

Cat.No: T76373L

Synonym: Ser-Ala-alloresact acetate(140653-27-6 Free base)

Target: Calcium Channel

Cat.No: T28174

Synonym: BA32644,BA-32644,Ambilhar,BA 32644

Cat.No: T28082

Human β-defensin-1

Cat.No: T40550

Synonym: Human β-defensin-1,HβD-1

Cat.No: T7487

Synonym: 精子活化肽

Target: Others, Mitochondrial Metabolism

Cat.No: T10810

Target: Others

Ser-Ala-alloresact

Cat.No: T76373

Cat.No: T71913

RU1968 bis-TFA salt

Cat.No: T70252

Cat.No: T83960

Cat.No: T36781

Synonym: st-Ht31 P

Cat.No: T69215

st-Ht31 ammonium

Cat.No: T83683

Synonym: sHt31

Cat. No.	Product Name	Target	Signaling Pathways
T7849	Norspermine	Others	Others
	Norspermine 是一种多胺类似物，用于治疗非小细胞肺癌和乳腺癌。
TN6088	tricoumaroyl spermidine N1,N5,N10-(Z)-tri-p-coumaroylspermidine,N1,N5,N10-(E)-Tri-p-coumaroylspermidine,N1,N5,N10-Tri-p-coumaroylspermidine	5-HT Receptor	GPCR/G Protein; Neuroscience
	Tricoumaroyl spermidine(N1,N5,N10-(Z)-tri-p-coumaroylspermidine) 被发现是一种独特的茶(Camellia sinensis) 花代谢物。
TN3466	Atherosperminine	cAMP; Calcium Channel; AChR; Parasite	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	Atherosperminine 是一种天然生物碱，在体外表现出抗疟原虫活性，IC50为 5.80 μM。它具有DPPH 自由基清除活性，其IC50值为 29.56 µg/mL。它对气管有非特异性的弛缓作用。它是一种良好的还原剂，具有螯合金属的能力。
T3007	Spermine Gerontine,Musculamine,精胺,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine	Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Spermine (Neuridine) 作为一个直接的自由基清除剂，具有抗病毒作用，能够保护 DNA 免受自由基的攻击。
TN6787L	N-Noratherosperminine hydrochloride N-Noratherosperminine hydrochloride (74606-53-4 free base)	Others	Others
	N-Noratherosperminine hydrochloride 是生物碱盐酸盐。 Noratherosperminine 可从 Cryptocarya nigra 中提取。
T5080	Spermidine trihydrochloride Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride,三盐酸亚精胺,亚精胺盐酸盐	NMDAR; Autophagy	Autophagy; Neuroscience
	Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride) 能够维持细胞膜稳定性，提高抗氧化酶特性，改善光系统 II (PSII) 以及相关基因表达，也能够显著抑制 H2O2和 O2.-含量。
T3093	Spermine tetrahydrochloride 精胺盐酸盐,Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Spermine tetrahydrochloride (Musculamine tetrahydrochloride) 是内源性代谢产物的一种。
T3784	Lithospermoside Griffonin,紫草氰苷	Others	Others
	Lithospermoside (Griffonin) 是一种分离自 Ochna schweinfurthiana F.Hoffm 茎皮中的天然产物。
T20793	Magnesium Lithospermate B 丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B	Others	Others
	Magnesium Lithospermate B 是一种咖啡酸四聚体的衍生物，从Salviae miltiorrhizae 中提取得到。它能够抑制神经炎症并减轻神经变性。它被广泛用于心血管疾病的研究，并且可以防止葡萄糖引起的细胞内氧化损伤。
T8299	Dimethyl lithospermate B 丹酚酸B二甲酯,dmLSB	Sodium Channel	Membrane transporter/Ion channel
	Dimethyl lithospermate B (dmLSB) 是 Na+通道的选择性激动剂，减缓钠电流 (INa) 失活，导致动作电位 (AP) 早期内向电流增加。
T19466	N8-Acetylspermidine dihydrochloride N8-乙酰基亚精胺二盐酸盐	Endogenous Metabolite	Metabolism
	N8-Acetylspermidine dihydrochloride 是一种多胺物质。
T3683	lithospermic acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Lithospermic acid 是一种植物来源的多环酚类羧酸，从丹参中分离得到，对 CCl4诱导的急性和体外肝损伤具有抗氧化和保肝活性。
TQ0308	Castanospermine 1,6,7,8-Tetrahydroxyoctahydroindolizine,栗精胺,亚胺糖栗树精胺,(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine	Glucosidase	Metabolism
	Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) 能够抑制α- and β-glucosidases 的所有形式。
T4893	Spermidine N-(3-Aminopropyl)-1,4-diaminobutane,亚精胺,N-(4-Aminobutyl)-1,3-diaminopropane	Endogenous Metabolite	Metabolism
	Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) 能够维持细胞膜稳定性，提高抗氧化酶活性，改善光系统 II 以及相关基因表达。它结合并激活 NMDA，并已显示以浓度依赖性方式增强 NMDA 诱导的电流。
TN6528	Butyrospermol	Others	Others
	Butyrospermol 是一种从乳木果（大戟属植物）中提取的protolimonoid，是首次从天然产物中发现的长链脂肪酸酯，具有拒食和抗肿瘤活性。
T32799	Lithospermidin B
	Lithospermidin B is a minor pigment isolated from the roots of L. erythrorhizon.
TN6556	Safflospermidine B
	Safflospermidine B is a potential natural tyrosinase inhibitor, it shows high antityrosinase activity (IC50 of 31.8μM).
TN6553	N1,N5,N10-(E)-tri-p-coumaroylspermidine
	N1,N5,N10-(E)-tri-p-coumaroylspermidine shows free radical-scavenging activity.
TN4934	Salaspermic acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
TN3109	5-Epilithospermoside	Others	Others
	(-)-5-Epilithospermoside is proposed as a potential marker of botanical origin for phacelia honey.
TN6555	Safflospermidine A
	Safflospermidine A is a potential natural tyrosinase inhibitor,it shows high antityrosinase activity (IC50 of 13.8 μM).
T80937	Tris(dihydrocaffeoyl)spermidine
	Tris(dihydrocaffeoyl)spermidine为活性化合物，从马铃薯(Solanum tuberosum)块茎中分离得到，主要用于代谢研究。
TN3323	Monomethyl lithospermate Lithospermic acid monomethyl ester	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Monomethyl lithospermate (Lithospermic acid monomethyl ester) 具有潜在的抗病毒活性，通过激活PI5K/Akt信号传导，减轻体内大脑中动脉闭塞小鼠缺血性中风损伤，并在体外保护氧葡萄糖剥夺/复氧诱导的SHSY-3Y细胞。Monomethyl lithospermate 能提高 SHSY-5Y 细胞的生存能力，抑制线粒体膜电位 (MMOP) 崩溃，抑制细胞凋亡。Monomethyl lithospermate 还降低中动脉闭塞 (MCAO) 大鼠脑组织中的氧化应激水平，改善缺血性中风 (IS) 大鼠神经损伤。
TN4621	N1,N10-Bis(p-coumaroyl)spermidine	Glucosidase	Metabolism
	N1,N10-Bis(p-coumaroyl)spermidine 对α-葡萄糖苷酶有抑制作用，可从苜蓿的草本植物中提取。
T35770	Cylindrospermopsin
	Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...
TN6787	N-noratherosperminine	Others	Others
	N-noratherosperminine 是 Cryptocarya nigra 茎皮的生物碱提取物。
T81717	N1-Dihydrocaffeoyl, N10-caffeoyl spermidine
	N1-Dihydrocaffeoyl, N10-caffeoyl spermidine为源自Lycium ruthenicum Murr.的天然化合物，可通过分离提取得到。
T3894	Polyphyllin II 重楼皂苷 II,Chonglou Saponin II	Apoptosis; Others	Apoptosis; Others
	Polyphyllin II (Chonglou Saponin II) 是重楼中重要的一种皂苷，具有止血、祛痰、抑菌、抗细胞毒和抗孕杀精作用。它通过 caspases 激活和细胞周期停滞诱导细胞凋亡。
T3229	Cytochalasin D	ATPase; p38 MAPK; Calcium Channel; Akt; PI3K	Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. Cytochalasin D inhibit
T6S2315	Polyphyllin VI	Apoptosis; Antibacterial; Pyroptosis	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Polyphyllin VI 是一种活性皂甙，诱导 G2/M 细胞周期停滞并引发细胞凋亡，具有抗癌活性。它通过诱导非小细胞肺癌中的 ROS/NF-κB/NLRP3/GSDMD 信号轴来诱导 caspase-1 介导的细胞焦亡。
T2S0122	D-(-)-Mandelic acid Mandelic acid,(R)-(-)-Mandelic acid,D-(−)-Mandelic Acid,R-(−)-Mandelic Acid,D-(-)-扁桃酸,扁桃酸；D-扁桃酸;R-扁桃酸;D-苦杏仁酸;苯基乙醇酸	Others	Others
	D-(-)-Mandelic acid ((R)-(-)-Mandelic acid) 是一种提取自苦杏仁中的天然产物。
T40442	Propylparaben sodium Propyl4-hydroxybenzoatesodium,羟苯丙酯钠,Propylparahydroxybenzoatesodium
	Propylparaben sodium (propyl parahydroxybenzoate) is a naturally occurring antimicrobial preservative found in plants and bacteria. Widely utilized in cosmetics, pharmaceuticals, and foods, this compound impairs antral follicle growth and steroidogenic function by modifying the cell-cycle, apoptosis, and steroidogenesis pathways. Additionally, propylparaben sodium reduces sperm count and motility in rats.

天然产物

Cat.No: T7849

Target: Others

tricoumaroyl spermidine

Cat.No: TN6088

Synonym: N1,N5,N10-(Z)-tri-p-coumaroylspermidine,N1,N5,N10-(E)-Tri-p-coumaroylspermidine,N1,N5,N10-Tri-p-coumaroylspermidine

Target: 5-HT Receptor

Atherosperminine

Cat.No: TN3466

Target: cAMP, Calcium Channel, AChR, Parasite

Cat.No: T3007

Synonym: Gerontine,Musculamine,精胺,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine

Target: Influenza Virus, Endogenous Metabolite

N-Noratherosperminine hydrochloride

Cat.No: TN6787L

Synonym: N-Noratherosperminine hydrochloride (74606-53-4 free base)

Target: Others

Spermidine trihydrochloride

Cat.No: T5080

Synonym: Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride,三盐酸亚精胺,亚精胺盐酸盐

Target: NMDAR, Autophagy

Spermine tetrahydrochloride

Cat.No: T3093

Synonym: 精胺盐酸盐,Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride

Target: Others, Endogenous Metabolite

Lithospermoside

Cat.No: T3784

Synonym: Griffonin,紫草氰苷

Target: Others

Magnesium Lithospermate B

Cat.No: T20793

Synonym: 丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B

Target: Others

Dimethyl lithospermate B

Cat.No: T8299

Synonym: 丹酚酸B二甲酯,dmLSB

Target: Sodium Channel

N8-Acetylspermidine dihydrochloride

Cat.No: T19466

Synonym: N8-乙酰基亚精胺二盐酸盐

Target: Endogenous Metabolite

lithospermic acid

Cat.No: T3683

Target: HIV Protease

Castanospermine

Cat.No: TQ0308

Synonym: 1,6,7,8-Tetrahydroxyoctahydroindolizine,栗精胺,亚胺糖栗树精胺,(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine

Target: Glucosidase

Cat.No: T4893

Synonym: N-(3-Aminopropyl)-1,4-diaminobutane,亚精胺,N-(4-Aminobutyl)-1,3-diaminopropane

Target: Endogenous Metabolite

Cat.No: TN6528

Target: Others

Lithospermidin B

Cat.No: T32799

Safflospermidine B

Cat.No: TN6556

N1,N5,N10-(E)-tri-p-coumaroylspermidine

Cat.No: TN6553

Salaspermic acid

Cat.No: TN4934

Target: HIV Protease

5-Epilithospermoside

Cat.No: TN3109

Target: Others

Safflospermidine A

Cat.No: TN6555

Tris(dihydrocaffeoyl)spermidine

Cat.No: T80937

Monomethyl lithospermate

Cat.No: TN3323

Synonym: Lithospermic acid monomethyl ester

Target: Akt, PI3K

N1,N10-Bis(p-coumaroyl)spermidine

Cat.No: TN4621

Target: Glucosidase

Cylindrospermopsin

Cat.No: T35770

N-noratherosperminine

Cat.No: TN6787

Target: Others

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine

Cat.No: T81717

Cat.No: T3894

Synonym: 重楼皂苷 II,Chonglou Saponin II

Target: Apoptosis, Others

Cat.No: T3229

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Cat.No: T6S2315

Target: Apoptosis, Antibacterial, Pyroptosis

D-(-)-Mandelic acid

Cat.No: T2S0122

Synonym: Mandelic acid,(R)-(-)-Mandelic acid,D-(−)-Mandelic Acid,R-(−)-Mandelic Acid,D-(-)-扁桃酸,扁桃酸；D-扁桃酸;R-扁桃酸;D-苦杏仁酸;苯基乙醇酸

Target: Others

Propylparaben sodium

Cat.No: T40442

Synonym: Propyl4-hydroxybenzoatesodium,羟苯丙酯钠,Propylparahydroxybenzoatesodium

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