首页工具

登录

搜索结果

Search Results for " intake "

105

抑制剂 & 化合物

12

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
TP1898	HS024 HS 024	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	HS024 是一种选择性的MC4受体拮抗剂，可增加食物摄入，对 MC4、MC5、MC3 和 MC1 的Ki 分别为 0.29、3.29、5.45 和 18.6 nM。
T8425	Linoleoyl Ethanolamide	TRP/TRPV Channel	Membrane transporter/Ion channel
	Linoleoyl ethanolamide 是脂肪酸乙醇酰胺。它可弱结合 CB1 和 CB2 受体，并分别抑制[3H]CP-55,940的结合，Ki 分别为 10 和 25μM。它在引起小鼠过氧化氢酶方面的效力是 anandamide 的4倍，且对睡眠时间无延长效果。
T6658	SB-408124 N-(6,8-二氟-2-甲基-4-喹啉)- N-[4-(二甲氨基)苯基]尿素	OX Receptor	GPCR/G Protein; Neuroscience
	SB408124 是一种 OX1 受体的非肽拮抗剂，在全细胞和膜中的 Ki 值分别为 57 和 27 nM，其选择性是 OX2 受体的 50 倍。
T6140	SB-334867 free base SB334867A free base,SB-334867,SB 334867,SB334867	OX Receptor	GPCR/G Protein; Neuroscience
	SB-334867 free base (SB334867A free base) 是一种选择性 orexin-1(OX1) 受体拮抗剂，对 OX2有选择性，pKb 为7.4，对 5-HT2B、5-HT2C 的选择性是 100 倍，pKi 值分别为 5.4 和 5.3。它减少乙醇消耗，还抑制吗啡诱导的体内运动活动敏感性的获得。
TP1793	Nociceptin (1-13), amide	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Nociceptin (1-13), amide 是一种 ORL1 (OP4) 受体激动剂，与大鼠前脑膜结合的 Ki 为 0.75 nM，对小鼠输精管的 pEC50 为 7.9。
T26986	Cevoglitazar LBM-642,LBM 642,LBM642	PPAR	DNA Damage/DNA Repair; Metabolism
	Cevoglitazar (LBM-642) 是一种 PPARɑ 激动剂和 PPARγ激动剂。Cevoglitazar 能有效减少肥胖小鼠和猴的食物摄入量和体重。
T0001	Iron(II) fumarate Ferrous fumarate,Iron Fumarate,富马酸铁 (II),富马酸亚铁	Others	Others
	Iron(II) fumarate (Ferrous fumarate) 是一种口服活性膳食补充剂，是一种富马酸的铁 (II) 盐，可用于研究缺铁性贫血。
T76664	Adropin (34-76) (human, mouse, rat)
	Adropin (34-76) (human, mouse, rat) 是一种多肽，可减轻肝纤维化和胰岛素抵抗，而不依赖于肥胖或食物摄入。
TP1305	LEP(116-130)(mouse)	Others	Others
	LEP(116-130)(mouse) 是合成的瘦素肽片段之一。
T15679	L 152804	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	L 152804 是神经肽 Y Y5 受体的特异性拮抗剂，可调节食物摄入和能量消耗，从而导致饮食诱导的肥胖小鼠体重减轻。
T15006	Dirlotapide CP742033,Slentrol	Others; CETP	Metabolism; Others
	Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加肽YY 释放到循环中。
T11451	GPI-1046 1-(1,2-二氧代-3,3-二甲基戊基)-L脯氨酸-(3-吡啶基)-丙酯	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	GPI-1046 是一种无抗生素作用的亲免素配体，部分通过上调 PFC 和 NAc 核心中的谷氨酸转运蛋白 1 来减少乙醇摄入。
TP1984L	[D-Trp34]-Neuropeptide Y Acetate [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	[D-Trp34]-Neuropeptide Y Acetate 是有效的、选择性的神经肽 Y (NPY) Y5 受体激动剂，在 NPY Y1，Y2，Y4 和 y6 受体上的效力较低。[D-Trp34]-Neuropeptide Y Acetate 可以显著增加大鼠的食物摄入量。
TP1889	MCL0020 MCL 0020	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	MCL0020 是一种有效的选择性黑素皮质素MC4受体拮抗剂，IC50为 11.63 nM。它剂量依赖性减轻束缚应激诱发的厌食症，在体内表现出抗焦虑样活性。
TP1996	MCH(human, mouse, rat) MCH (human, mouse, rat),黑色素聚集激酶素(MCH)( 大鼠)	GPR; Melanin-concentrating Hormone Receptor (MCHR)	Endocrinology/Hormones; GPCR/G Protein
	MCH(human, mouse, rat) 是MCH-R 肽激动剂，对 CHO 细胞系中 MCH-2R 高度敏感，激活 MCH-1R 和 MCH-2R 的IC50 值分别为 0.3 和 1.5 nM，EC50值对分别为 3.9 和 0.1 nM。
TP2279L	Obestatin (rat) acetate	GHSR	GPCR/G Protein
	Obestatin (rat) acetate 是 G 蛋白偶联受体 39 (GPR39) 的内源性配体。它具有抗炎、抗心肌梗塞和抗氧化特性。它抑制食物摄入，抑制空肠收缩，并减少体重增加。
TP2015L	HS 014 acetate(207678-81-7 free base)	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	HS 014 acetate(207678-81-7 free base) 是一种有效的选择性黑皮质素 MC4 受体拮抗剂（克隆的人 MC4、MC1、MC3 和 MC5 受体的 Ki 值分别为 3.16、108、54.4 和 694 nM）。体内中枢给药后增加大鼠的食物摄入和小鼠的伤害感受。还抑制室旁下丘脑中 IL-1β 诱导的 Fos 表达。
T8720	PRX-07034 hydrochloride PRX-07034	5-HT Receptor	GPCR/G Protein; Neuroscience
	PRX-07034 hydrochloride 是一种有效的高度选择性5-HT6受体拮抗剂，Ki 为 4-8 nM，IC50为 19 nM，可用于增强工作记忆和认知灵活性的研究。
TP1992L	M40 acetate(143896-17-7 free base)	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	M40 acetate(143896-17-7 free base) 是一种有效的、非选择性的甘丙肽受体拮抗剂（GAL1 和 GAL2 的 Ki 值分别为 1.82 和 5.1 nM），在体外抑制大鼠脑中甘丙肽 (1-29) 的结合 (IC50 = 3 - 15 nM)。减弱氟西汀的抗抑郁作用并阻止甘丙肽诱导的体内食物摄入。在剂量 > 100 nM 时，对外周 GAL2 受体也表现出较弱的部分激动剂活性。
T62929	RLX-33	ERK; RXFP receptor	GPCR/G Protein; MAPK
	RLX-33 是一种有效的、选择性的、能够透过血脑屏障的松弛素家族肽 3 (RXFP3) 拮抗剂，也能够阻断松弛素 3 (relaxin 3) 诱导的 ERK1/2 磷酸化。RLX-33 作用于 RXFP3、ERK1 和 ERK2 磷酸化的 IC50 分别为 2.36 μM、7.82 μM 和 13.86 μM。RLX-33 可以阻断 RXFP3 选择性激动剂 R3/I5 诱导的大鼠食物摄取增加。RLX-33 能够用于研究代谢综合征。
T26305	U 67827E N-Ac-Asp-tyr(So3H)-nle-gly-trp-nle-asp-phe-NH2,U-67827E,U67827E
	U 67827E is a long-lasting cholecystokinin agonist. It acts by decreases food intake.
T16086	MK-0493	Others	Others
	MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.
T31073	CP-671906 CP-671906-01,UNII-GLZ1WA47Q8
	CP-671906 is a neuropeptide Y1 receptor antagonist which increases blood pressure and food intake in rat models.
T68565	ANN33840
	ANN33840 is a novel selective 5-HT2C agonist with >300-fold functional selectivity over 5-HT2B and >70-fold functional selectivity over 5-HT2A, reducing food intake in an acute rat feeding model.
T27550	HMR-1426 HMR 1426,HMR1426
	HMR-1426 is gastric emptying inhibitor. HMR1426 shows an anorectic potential in rats and decreased body weight and fat mass. This was achieved solely by reducing food intake without influencing overall energy expenditure or behavior.
TP2279	Obestatin(rat) Obestatin (rat)	Others	Others
	Endogenous peptide that suppresses food intake and body weight-gain
TP1835	Enterostatin(human,mouse,rat) Enterostatin, human, mouse, rat
	Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.
T26935	C108297 C-108297,C 108297
	C108297 is a glucocorticoid receptor modulator. C108297 prevents both diet-induced obesity and inflammation. C108297 decreased food and fructose intake and increased lipolysis in white adipose tissue (WAT) and free fatty acid levels in plasma, resulting i
T71001	GSK-598809
	GSK598809 is a selective D(3)R antagonist recently progressed in Phase I trials. GSK-598809 may decrease the rewarding effects of contextual cues associated with drug intake preclinically, which may reduce drug craving in humans.
T35793	JMV3002 JMV3002
	Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when test...
T35631	Peptide YY (human) (trifluoroacetate salt) Peptide Tyrosine Tyrosine
	Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation. PYY is cleaved in vivo to PYY (3-36) . Release of PYY occurs postprandially in proportion to calorie intake from intestinal enteroendocrine L cells, indicating it may be a satiety signal. In humans, PYY inhibits food intake and gastrointestinal transit in...
T37131	MS 15203
	Potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice. Wardman et al (2016) Identification of a small-molecule ligand that activates the neuropeptide receptor GP...
T5406	SNAP 94847 SNAP-94847	GPR; Melanin-concentrating Hormone Receptor (MCHR)	Endocrinology/Hormones; GPCR/G Protein
	SNAP 94847 (SNAP-94847) 是一种选择性黑色素浓缩激素受体1 拮抗剂，Ki 为 2.2 nM。它具有抗焦虑和抗抑郁活性，可减少小鼠的食物摄入。
T81625	Obestatin(human) TFA
	Obestatin(human) TFA, 同源于与ghrelin相同的前体多肽，是一种内源性肽。该化合物抑制大鼠食欲并降低体重增加。
TP1916	[D-Phe12,Leu14]-Bombesin
	Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
T62179	rel-O-2050
	rel-O-2050 (Compound O-2050) 是一种中性的大麻素受体 (cannabinoid CB1receptor) 拮抗剂，能够降低小鼠的食物摄入量。
TP1941	Ac-RYYRWK-NH2
	Potent, selective partial agonist peptide for the NOP receptor (Ki = 0.71 nM). Selective over μ, δ and κ opioid receptors (IC50 > 4000 nM). Increases food intake in vivo.
TP1139	Orexin B, human Human orexin B
	Orexin B, human is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. Orexin B is a hypothalamatic neuropeptide stimulating food intake in rats.
TP2073	BigLEN(mouse) BigLEN (mouse)
	GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
TP1148	Glucagon-like peptide 1 (1-37), human HuGLP-1
	Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats and does not en
T29938	AM-3102 KDS-5104,AM 3102,Methyl oleoylethanolamide
	AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding r
T38959	BMS-604992 dihydrochloride EX-1314 dihydrochloride,BMS-604992 dihydrochloride
	BMS-604992 (EX-1314) dihydrochloride is a selective and orally active small-molecule agonist of the growth hormone secretagogue receptor (GHSR). It exhibits high-affinity binding (k i = 2.3 nM) and potent functional activity (EC 50 = 0.4 nM). Furthermore, BMS-604992 dihydrochloride has been shown to stimulate food intake in rodents.
T37371	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid
	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.
T40876	BMS-604992 free base BMS-604992 free base,EX-1314 free base
	BMS-604992 (EX-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. It exhibits high-affinity binding (k i = 2.3 nM) and potent functional activity (EC 50 = 0.4 nM). Moreover, BMS-604992 free base has the ability to stimulate food intake in rodents.
T37783	2,5-Anhydro-D-mannitol
	2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, which decreases available ATP and signals eating behavior in rats through a vagal nerve mechanism.
TP2011	JKC363 JKC 363
	Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, attenuates food intake and reduces forma
T82733	Cholecystokinin CCK-33(human),Cholecystokinin-33(human)
	Cholecystokinin是一种通过抑制食物摄入并促进脂肪及蛋白质消化作用的肽类激素，常用于胃肠系统研究。
T21811	LH 21
	LH-21 是一种有效的体内中性大麻素 CB1受体拮抗剂。LH-21 会导致剂量依赖性进食抑制，减少肥胖 Zucker 大鼠的食物摄入和体重增加。
TP2015	HS014 HS 014
	Potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in v
TP1963	[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
	Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.

化合物

Cat.No: TP1898

Synonym: HS 024

Target: Melanocortin Receptor

Linoleoyl Ethanolamide

Cat.No: T8425

Target: TRP/TRPV Channel

Cat.No: T6658

Synonym: N-(6,8-二氟-2-甲基-4-喹啉)- N-[4-(二甲氨基)苯基]尿素

Target: OX Receptor

SB-334867 free base

Cat.No: T6140

Synonym: SB334867A free base,SB-334867,SB 334867,SB334867

Target: OX Receptor

Nociceptin (1-13), amide

Cat.No: TP1793

Target: Opioid Receptor

Cat.No: T26986

Synonym: LBM-642,LBM 642,LBM642

Target: PPAR

Iron(II) fumarate

Cat.No: T0001

Synonym: Ferrous fumarate,Iron Fumarate,富马酸铁 (II),富马酸亚铁

Target: Others

Adropin (34-76) (human, mouse, rat)

Cat.No: T76664

LEP(116-130)(mouse)

Cat.No: TP1305

Target: Others

Cat.No: T15679

Target: Neuropeptide Y Receptor

Cat.No: T15006

Synonym: CP742033,Slentrol

Target: Others, CETP

Cat.No: T11451

Synonym: 1-(1,2-二氧代-3,3-二甲基戊基)-L脯氨酸-(3-吡啶基)-丙酯

Target: Others, HIV Protease

[D-Trp34]-Neuropeptide Y Acetate

Cat.No: TP1984L

Synonym: [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)

Target: Neuropeptide Y Receptor

Cat.No: TP1889

Synonym: MCL 0020

Target: Melanocortin Receptor

MCH(human, mouse, rat)

Cat.No: TP1996

Synonym: MCH (human, mouse, rat),黑色素聚集激酶素(MCH)( 大鼠)

Target: GPR, Melanin-concentrating Hormone Receptor (MCHR)

Obestatin (rat) acetate

Cat.No: TP2279L

Target: GHSR

HS 014 acetate(207678-81-7 free base)

Cat.No: TP2015L

Target: Melanocortin Receptor

PRX-07034 hydrochloride

Cat.No: T8720

Synonym: PRX-07034

Target: 5-HT Receptor

M40 acetate(143896-17-7 free base)

Cat.No: TP1992L

Target: Neuropeptide Y Receptor

Cat.No: T62929

Target: ERK, RXFP receptor

Cat.No: T26305

Synonym: N-Ac-Asp-tyr(So3H)-nle-gly-trp-nle-asp-phe-NH2,U-67827E,U67827E

Cat.No: T16086

Target: Others

Cat.No: T31073

Synonym: CP-671906-01,UNII-GLZ1WA47Q8

Cat.No: T68565

Cat.No: T27550

Synonym: HMR 1426,HMR1426

Cat.No: TP2279

Synonym: Obestatin (rat)

Target: Others

Enterostatin(human,mouse,rat)

Cat.No: TP1835

Synonym: Enterostatin, human, mouse, rat

Cat.No: T26935

Synonym: C-108297,C 108297

Cat.No: T71001

Cat.No: T35793

Synonym: JMV3002

Peptide YY (human) (trifluoroacetate salt)

Cat.No: T35631

Synonym: Peptide Tyrosine Tyrosine

Cat.No: T37131

Cat.No: T5406

Synonym: SNAP-94847

Target: GPR, Melanin-concentrating Hormone Receptor (MCHR)

Obestatin(human) TFA

Cat.No: T81625

[D-Phe12,Leu14]-Bombesin

Cat.No: TP1916

Cat.No: T62179

Cat.No: TP1941

Orexin B, human

Cat.No: TP1139

Synonym: Human orexin B

Cat.No: TP2073

Synonym: BigLEN (mouse)

Glucagon-like peptide 1 (1-37), human

Cat.No: TP1148

Synonym: HuGLP-1

Cat.No: T29938

Synonym: KDS-5104,AM 3102,Methyl oleoylethanolamide

BMS-604992 dihydrochloride

Cat.No: T38959

Synonym: EX-1314 dihydrochloride,BMS-604992 dihydrochloride

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid

Cat.No: T37371

BMS-604992 free base

Cat.No: T40876

Synonym: BMS-604992 free base,EX-1314 free base

2,5-Anhydro-D-mannitol

Cat.No: T37783

Cat.No: TP2011

Synonym: JKC 363

Cholecystokinin

Cat.No: T82733

Synonym: CCK-33(human),Cholecystokinin-33(human)

Cat.No: T21811

Cat.No: TP2015

Synonym: HS 014

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

Cat.No: TP1963

Synonym: cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide

Cat. No.	Product Name	Target	Signaling Pathways
T12045	(-)-Hydroxycitric acid lactone 藤黄内酯,Garcinia lactone	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种有效的 ATP-柠檬酸裂解酶抑制剂，能够催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。它是一种减肥药，是一种广受欢迎的减肥食品补充剂。
T0948L	Corticosterone 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Corticosterone (Kendall's compound B) 是一种肾上腺皮质类固醇，有盐皮质激素和糖皮质激素的活性，具有口服活性。Corticosterone 参与体内能量、免疫反应和应激反应的调节。
T9297	Perseitol	Others	Others
	Perseitol 是一种产生于成熟的鳄梨植物的化合物。它能够转变为 D-甘露庚酮糖，可提供能量以及运输碳水。
TN6764	Simmondsin	Others	Others
	Simmondsin 是一种来自Simmondsia chinensis——荷荷巴的天然产物。它减少了大鼠的食物摄入量和体重，而没有明显的负面影响。
TN1740	Homoeriodictyol 高胜草酚,高圣草酚	5-HT Receptor; transporter; Sodium Channel; Drug Metabolite	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Homoeriodictyol 是 Eriocitrin 的代谢物，属于黄酮类。Eriocitrin 是强效抗氧化剂。
T11590	(-)-Hydroxycitric acid Garcinia acid,(-)-羟基柠檬酸	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid (Garcinia acid) 是Garcinia cambogia 果皮中的主要酸。它是 ATP 柠檬酸裂解酶的竞争性抑制剂，能够抑制脂肪酸的合成，减少脂肪生成，控制食物摄入，从而减轻体重。
T3727	Methyl syringate Syringic Acid Methyl Ester,丁香酸甲酯	TRP/TRPV Channel	Membrane transporter/Ion channel
	Methyl syringate (Syringic Acid Methyl Ester) 是水仙花蜜的化学标记物，是有效的细菌和真菌漆酶酚介质。它也是TRPA1激动剂。
T2P2923	Stearic acid 硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase; Endogenous Metabolite	Metabolism
	Stearic acid (Cetylacetic acid) 是长链饱和脂肪酸，存在于许多动植物油脂中。
T4903	Heptadecanoic acid	Others; Endogenous Metabolite	Metabolism; Others
	Heptadecanoic acid 是奇链饱和脂肪酸，与一些疾病（如冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症）有关。
T4877	L-Homocystine	Endogenous Metabolite	Metabolism
	L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子，也是研究心血管疾病发生机制的内质网应激反应的诱导剂。
T13752	L-(+)-Arabinose	Endogenous Metabolite	Metabolism
	L-(+)-Arabinose 能够选择性抑制肠道蔗糖酶，并抑制因蔗糖摄入而导致的血浆葡萄糖提高。
TN1751	Hydroxycitric acid	ERK; p38 MAPK; Fatty Acid Synthase	MAPK; Metabolism
	(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis.

天然产物

(-)-Hydroxycitric acid lactone

Cat.No: T12045

Synonym: 藤黄内酯,Garcinia lactone

Target: ATP Citrate Lyase

Cat.No: T0948L

Synonym: 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

Cat.No: T9297

Target: Others

Cat.No: TN6764

Target: Others

Homoeriodictyol

Cat.No: TN1740

Synonym: 高胜草酚,高圣草酚

Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite

(-)-Hydroxycitric acid

Cat.No: T11590

Synonym: Garcinia acid,(-)-羟基柠檬酸

Target: ATP Citrate Lyase

Methyl syringate

Cat.No: T3727

Synonym: Syringic Acid Methyl Ester,丁香酸甲酯

Target: TRP/TRPV Channel

Cat.No: T2P2923

Synonym: 硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid

Target: Phosphatase, Endogenous Metabolite

Heptadecanoic acid

Cat.No: T4903

Target: Others, Endogenous Metabolite

Cat.No: T4877

Target: Endogenous Metabolite

L-(+)-Arabinose

Cat.No: T13752

Target: Endogenous Metabolite

Hydroxycitric acid

Cat.No: TN1751

Target: ERK, p38 MAPK, Fatty Acid Synthase

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼