72
14
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0776 |
Phenothiazine
ENT 38,吩噻嗪 |
Dopamine Receptor; Antibacterial; Antibiotic; Antifungal | GPCR/G Protein; Microbiology/Virology; Neuroscience |
Phenothiazine (ENT 38) 是一种抗生素,具有杀虫,抗菌,驱虫和杀真菌活性。它也可研究神经系统疾病。 | |||
T1546 |
Nitazoxanide
NSC 697855,硝唑尼特 |
Others; Influenza Virus; Parasite; Autophagy | Autophagy; Microbiology/Virology; Others |
Nitazoxanide (NSC-697855) 是一种广谱驱虫剂,对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。 它在无菌培养中抑制Giardia lamblia 滋养体增殖,IC50为 2.4 μM。它可研究寄生虫性胃肠炎,具有抗病毒特性。 | |||
T19807 |
Dithiazanine iodide
Delvex,Telmide,Vercidon,Abminthic,Netocyd,NSC 221154 |
Others | Others |
Dithiazanine iodide (Netocyd) 是一种苯并噻唑。它已被用作抗虫剂。它作为纳米颗粒在治疗胶质母细胞瘤方面也很有效。 | |||
T0314 |
Hexylresorcinol
己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol |
Apoptosis; Tyrosinase; Antibacterial; Parasite | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物,具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂,有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。 | |||
T16126 |
Monepantel
AAD1566 |
Others | Others |
Monepantel is an organic anthelmintic. Monepantel is also used for a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits. | |||
T0237 |
Closantel
氯氰碘柳胺,R-31520,氯生太尔 |
Antibacterial; Parasite | Microbiology/Virology |
Closantel (R-31520) 是抗寄生虫活性的卤化水杨酰苯胺。它是高度特异性盘尾丝虫几丁质酶抑制剂。 | |||
T7901 |
Emodepside
Bay 44-4400 |
Parasite | Microbiology/Virology |
Emodepside (Bay 44-4400) 是一种对多种胃肠道线虫有效的驱虫药,具有广谱驱虫活性。 | |||
T10850L |
CMP-5 2HCl
|
Others | Others |
CMP-5 2HCl 是一种驱虫剂。CMP-5 2HCl 体外抗H. contortus 的EC100为5μM。 | |||
T6452 |
Closantel Sodium
|
Antibacterial; Parasite | Microbiology/Virology |
Closantel sodium 是抗寄生虫活性的卤化水杨酰苯胺。它是高度特异性的盘尾丝虫几丁质酶抑制剂。 | |||
T7887 |
8-Hydroxyquinoline hemisulfate
8-羟基喹啉硫酸盐,Oxyquinoline sulfate |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) 是一种单质子双齿螯合剂,具有温和的抑菌、驱虫和杀螨作用。 | |||
T1343L |
Crystal Violet
Methyl Violet 10B,Hexamethylpararosaniline chloride,氯化结晶紫,Basic Violet 3,结晶紫,Gentian Violet |
DNA; Influenza Virus; Antibacterial | DNA Damage/DNA Repair; Microbiology/Virology |
Crystal Violet (Hexamethylpararosaniline chloride) 是革兰氏染色染料。它对H1N1具有抗病毒作用,有显著杀菌活性。 | |||
T7146 |
Piperazine adipate
|
Parasite | Microbiology/Virology |
Piperazine adipate 是一种广谱驱虫剂,可抵抗哺乳动物中很多常见的寄生虫感染。 | |||
T20082 |
Dymanthine
十八烷基二甲基叔胺,Adogen 342D,ADMA 18 |
Others | Others |
Dymanthine (ADMA 18) 是驱虫药,对多种肠道蠕虫感染具有潜在的研究价值。 | |||
T7605 |
Avermectin B1a
阿维菌素 B1a,Abamectin B1a,Avamectin B1a |
Antibiotic; Parasite | Microbiology/Virology |
Avermectin B1a 是能够使线虫瘫痪的一种抗寄生虫剂。 | |||
T16539 |
Piperazine citrate
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Piperazine citrate 是一种六元环化合物,有驱虫的作用。 | |||
T30819 |
CGP 20376
CGP-20376,CGP20376 |
||
CGP 20376 是一种苯并噻唑化合物,是一种驱虫剂,对嗜酸性粒细胞呼吸爆发的双重剂量依赖性调节体外作用,具有抗纤特性。 | |||
T0714 |
Oxfendazole
奥吩达唑,奥芬哒唑,RS-8858 |
Glucokinase; Microtubule Associated; Parasite | Cytoskeletal Signaling; Metabolism; Microbiology/Virology |
Oxfendazole (RS-8858) 是fenbendazole 的亚砜形式,是广谱苯并咪唑驱虫剂,可保护牲畜免受蛔虫、圆线虫和蛲虫的侵害。 | |||
T15272 |
Febantel
|
Parasite | Microbiology/Virology |
Febantel 是一种用于家禽和家畜的蛔虫、绦虫感染的驱虫剂。 | |||
T0395 |
Pyrantel tartrate
Banminth,酒石酸噻吩嘧啶 |
Antibiotic; Parasite | Microbiology/Virology |
Pyrantel tartrate (Banminth) 是一种四氢嘧啶类广谱牲畜驱虫剂,是烟碱乙酰胆碱受体激动剂。它能引起寄生虫的痉挛性肌肉麻痹。它可研究胃肠道线虫感染。 | |||
T5836 |
Eprinomectin
依普菌素,MK-397 |
Parasite | Microbiology/Virology |
Eprinomectin (MK-397) 是一种阿维菌素,具有驱虫,杀虫杀螨活性。 | |||
T6372 |
Albendazole sulfoxide
Ricobendazole,Albendazole Oxide,阿苯达唑亚砜 |
Microtubule Associated; Parasite | Cytoskeletal Signaling; Microbiology/Virology |
Albendazole sulfoxide (Ricobendazole) 是一种驱虫药阿苯达唑的代谢物,有抗寄生虫活性。 | |||
T30596 |
Brotianide
BAY-VA 4059,Dirian,BAY-VA-4059,BAY-VA4059 |
Parasite | Microbiology/Virology |
Brotianide (BAY-VA4059) 具有驱虫活性,对肝吸虫和胃吸虫侵染具有很高的效力,可用于治疗绵羊的急性、亚急性和慢性肝脏法氏囊病感染。 | |||
T77507 | (-)-Benzotetramisole | ||
(-)-Benzotetramisole 使一种高效且具有选择性的催化剂。(-)-Benzotetramisole 是抗蠕虫化合物四咪唑3 的苯annulated 衍生物,本身也是转化的有效催化剂。 | |||
T7093 |
Rafoxanide
碘醚柳胺,雷复尼特 |
CDK; Parasite | Cell Cycle/Checkpoint; Microbiology/Virology |
Rafoxanide 是口服活性水杨酰苯胺类驱虫剂。它作为抗寄生虫剂,可用于控制羊和牛的 Hemonchus 种和 Fasciola 种的感染。 | |||
T77684 |
4-(2-Aminoethyl)amino-7-chloroquinoline
N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine |
Parasite | Microbiology/Virology |
4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) 具有潜在的抗虫和抗肿瘤活性,可用于研究疟疾。 | |||
T0955 |
Oxyclozanide
Oxiclozanidum,Zanil,Oxyclozanid,Zanilox,氯羟柳胺 |
Antibiotic; Parasite | Microbiology/Virology |
Oxyclozanide (Oxyclozanid) 是一种水杨酰苯胺驱虫药,用于放牧动物的片形吸虫和绦虫感染。 | |||
T77643 |
2-(Chloromethyl)Imidazo[1,2-A]Pyridine
|
Others | Others |
2-(Chloromethyl)imidazo[1,2-a]pyridine 具有潜在的抗虫活性,可用于合成有活性的化合物。 | |||
T62769 |
Tribendimidine
|
AChR | Neuroscience |
Tribendimidine 是一种广谱的、口服具有活力的驱虫剂,也是一种 L 型烟碱乙酰胆碱受体 (nAChR) 激动剂。Tribendimidine 对 A. lumbricoides 和 N. americanus 具有极高的活性。 | |||
T1420 |
Diethylcarbamazine citrate
Caritrol,枸橼酸乙胺嗪,Loxuran,Dicarocide |
Lipoxygenase; COX; Parasite | Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Diethylcarbamazine citrate (Caritrol) 是驱肠虫药,主要用作治疗丝虫病的柠檬酸盐,是丝虫微丝蚴的花生四烯酸代谢抑制剂。 | |||
T0009 |
Flubendazole
氟苯咪唑,Flumoxanal,Flumoxane,NSC 313680,Fluvermal |
Apoptosis; Microtubule Associated; Parasite | Apoptosis; Cytoskeletal Signaling; Microbiology/Virology |
Flubendazole (Flumoxane) 是用于治疗人类蠕虫感染的驱虫药。它通过抑制微管功能等机制发挥抗癌作用。它诱导p53介导的细胞凋亡,抑制 G2/M 细胞周期。 | |||
T0066 |
Dichlorophen
双氯酚,DDM,Dichlorophene |
Antibacterial; Parasite; Antifungal | Microbiology/Virology |
Dichlorophen (DDM) 是一种抗微生物剂,对绦虫,原生动物,真菌和细菌具有活性,通过增加肠道内容物的清除,消除肠道中的绦虫感染。 | |||
T37072 |
Nitroxynil
4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix |
Parasite | Microbiology/Virology |
Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) 为一种广泛用于研究 Fasciola hepatica 感染的驱虫剂,有效作用于寄生虫的成熟及未成熟阶段。 | |||
T4059 |
Selamectin
UK-124114,司拉克丁,塞拉菌素 |
Chloride channel; P-gp; Parasite | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
Selamectin (UK-124114) 是半合成的大环内酯,是一种驱虫剂,可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂,可激活神经元和咽肌中的谷氨酸门控氯离子通道,以预防恶丝虫,淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂,IC50为 120 nM。 | |||
T0124 |
UK-124114
UNII-A2669OWX9N,西拉菌素,Selamectin |
Others | Others |
UK-124114 (Selamectin) 是伊维菌素的大环内酯衍生物,伊维菌素是一种驱虫剂,可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。在 H. contortus 幼虫发育试验中,赛拉菌素 (0.1 µg/ml) 显示出生长抑制作用。 | |||
T25188 |
Butonate
NSC17872,NSC 17872,NSC-17872 |
||
Butonate is an Anthelmintic agent. | |||
T0323L |
Oxantel
|
||
Oxantel is a fumarate reductase inhibitor with anthelmintic activity. | |||
T21473 |
Naftalofos
Naftalofosum,Rawetin,Maretin,Rametin,Naphthalophos |
||
Naftalofos is an anthelmintic and an insecticide. | |||
T34567 |
Sch 18099
Sch-18099,Sch18099 |
||
Sch 18099 showed anthelmintic activity. | |||
T30968 |
Clioxanide
Tremerad,SYD-230,SYD 230,Clioxanida,Clioxanidum |
||
Clioxanide is an anthelmintic agent. | |||
T34236 |
R 7-45
R 7/45,R7-45,R-7-45 |
||
R 7-45 is an organic arsenical that acts as an anthelmintic agent. | |||
T38675 |
Hikizimycin
Anthelmycin |
||
Hikizimycin is a potent anthelmintic and antibacterial natural product. | |||
T21476 |
Niclofolan
Niclofolano,Bilevon M,Menichlopholan,ME-3625,Niclofolanum |
||
Niclofolan, a biphenyl anthelmintic compound, is used orally towards the treatment of Fasciola hepatica infection. | |||
T20825 |
Diethylcarbamazine
RP3799,Diaethylcarbamazinum,AI3-19612,RP 3799,Bitirazine,RP-3799 |
||
Diethylcarbamazine, an anthelmintic, is used primarily as the citrate in the treatment of filariasis, particularly infestations with Loa loa or Wucheria bancrofti. | |||
T15462 |
Haloxon
|
Others | Others |
Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants. | |||
T13770 |
Melarsonyl
Melarsonic acid |
Others | Others |
Melarsonyl (Melarsonic acid) can inhibit parasite potently. Melarsonyl (Melarsonic acid) is an anthelmintic agent. | |||
T38729 |
Melarsonyl dipotassium
美拉胂钾,Melarsonic acid dipotassium |
||
Melarsonyl dipotassium, also known as melarsonic acid dipotassium, is a potent anthelmintic agent with the ability to effectively inhibit parasites. | |||
T26679 |
Atelocantel
AH 353623,AH-353623,AH353623 |
||
Atelocantel is an anthelmintic agent (veterinary drug). | |||
T34876 |
Ticarbodine
EL-974,EL 974,EL974 |
||
Ticarbodine(EL-974)is an Anthelmintic agent. | |||
T20624 |
Bitriben
Chloxyl,Cloxil,Fluorescent Red Mega 485 NHS-ester,Chloksil,Chloxil |
||
Bitriben is an agent with the anthelmintic effect. | |||
T20960 |
Luxabendazole
HOE 216V |
||
Luxabendazole is a benzimidazole carbamate broad-spectrum anthelmintic agent. It has proved to be effective against immature and adult stages of the major gastrointestinal nematodes, cestodes, and trematodes. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8193 |
α-Thujone
Thujone,ALPHA-(-)-THUJONE,α-侧柏酮,(-)-α-侧柏酮 |
Apoptosis; Reactive Oxygen Species; GABA Receptor; AChR; Parasite; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB |
α-Thujone 是一种从西方金钟柏精油中分离出来的单萜,可穿透血脑屏障。它是 GABAA 受体的可逆调节剂,在抑制 GABA 诱导的电流时,它的 IC50为 21 μM。它诱导 ROS 依赖性细胞毒性,还诱导细胞凋亡和自噬。它具有抗伤害,抗肿瘤、杀虫和驱虫活性。 | |||
T0956 |
Avermectin B1
Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素 |
Antibiotic; Parasite; Autophagy | Autophagy; Microbiology/Virology |
Avermectin B1 是驱虫杀虫剂。 | |||
T25114 |
Ascaridole
NSC-406266,NSC 406266,NSC406266 |
Parasite | Microbiology/Virology |
Ascaridole (NSC-406266) 可作为驱虫化合物,能驱除人体和植物中的寄生蠕虫(蠕虫),具有较弱的抗疟活性。 | |||
TN6718 |
Dehydrocostuslactone
|
Others | Others |
Dehydrocostuslactone 是一种从奥克兰提取的天然产物。它具有广泛的生物作用,包括抗炎、抗癌、抗病毒、抗菌、抗真菌、抗氧化、抗糖尿病、抗溃疡和驱虫活性。 | |||
T3S0006 |
(E)-Ferulic acid methyl ester
Methyl ferulate,Methyl (E)-ferulate,(E)-阿魏酸甲酯 |
IL Receptor; p38 MAPK; TNF; COX; NO Synthase; JNK; Antifection | Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience |
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) 具有较强 DPPH 和 ABTS+自由基清除特性。 | |||
TN2324 |
Yuankanin
|
Antioxidant | oxidation-reduction |
Yuankanin 是一种是在百里香叶、Daphne gnidium 和Daphne feddei 中发现的天然化合物,是一种 genkwanin-5-bioside,具有抗虫和抗氧化活性并对o- 1葡萄糖苷酶、脂肪酶、胰蛋白酶和黄嘌呤氧化酶具有抑制作用。 | |||
T1157 |
Moxidectin
milbemycin B,CL301423,莫昔克丁,莫西菌素 |
GluCls; Antibiotic; Parasite | Microbiology/Virology |
Moxidectin (CL301423) 是可用于预防和控制心丝虫和蛔虫的一种驱虫剂。 | |||
T16497 |
PF 1022A
|
Others | Others |
PF 1022A is an N-methylated cyclooctadepsipeptides with strong anthelmintic properties. It also acts as an ionosphere. | |||
T35908 |
Paraherquamide E
|
||
Paraherquamide E is a fungal metabolite originally isolated from P. charlesii with anthelmintic and insecticidal activities. It is lethal to C. elegans (LD50 = 6 μg/ml). Paraherquamide E is also lethal to O. fasciatus (LD50 = 0.089 μg/nymph). Oral administration of paraherquamide E (0.5-4 mg/kg) reduces T. colubriformis fecal egg count in gerbils. | |||
T38235 |
16-Keto Aspergillimide
|
||
16-Keto Aspergillimide (SB202327) is a novel anthelmintic compound derived from the Aspergillus strain IMI 337664. | |||
TN4639 |
Neolitsine
|
Others | Others |
Neolitsine has anthelmintic activity, it exhibits EC90 values (concentration at which 90% loss of larval motility is observed) of 6.4 microg/mL.Neolitsine and dicentrine have potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM. | |||
T82706 |
Clonostachydiol
|
||
Clonostachydiol为源于真菌Clonostachys cylindrospora(菌株FH-A 6607)的大分子内酯类驱虫药。 | |||
T75494 | Shinjulactone M | ||
Shinjulactone M 是一种从 Ailanthus 中分离出来的一种苦木苦味素类化合物。Ailanthus 可用作退热药 (抗疟) 和驱虫药,用于慢性支气管炎、癫痫和哮喘的研究。 | |||
T37609 |
(rel)-Asperparaline A
|
||
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces... |